Nuno Sousa - Publications

Affiliations: 
ECS University of Minho, Portugal 

168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Correia R, Coimbra B, Domingues AV, Wezik M, Vieitas-Gaspar N, Gaspar R, Sousa N, Pinto L, Rodrigues AJ, Soares-Cunha C. Involvement of nucleus accumbens D2-medium spiny neurons projecting to the ventral pallidum in anxiety-like behaviour. Journal of Psychiatry & Neuroscience : Jpn. 48: E267-E284. PMID 37437920 DOI: 10.1503/jpn.220111  0.541
2023 Martins-Macedo J, Mateus-Pinheiro A, Alves C, Veloso F, Gomes ED, Ribeiro I, Correia JS, Silveira-Rosa T, Alves ND, Rodrigues AJ, Bessa JM, Sousa N, Oliveira JF, Patrício P, Pinto L. StressMatic: A Novel Automated System to Induce Depressive- and Anxiety-like Phenotype in Rats. Cells. 12. PMID 36766724 DOI: 10.3390/cells12030381  0.777
2022 Soares-Cunha C, Domingues AV, Correia R, Coimbra B, Vieitas-Gaspar N, de Vasconcelos NAP, Pinto L, Sousa N, Rodrigues AJ. Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior. Cell Reports. 38: 110380. PMID 35172164 DOI: 10.1016/j.celrep.2022.110380  0.546
2022 Machado-Santos AR, Loureiro-Campos E, Patrício P, Araújo B, Alves ND, Mateus-Pinheiro A, Correia JS, Morais M, Bessa JM, Sousa N, Rodrigues AJ, Oliveira JF, Pinto L. Beyond New Neurons in the Adult Hippocampus: Imipramine Acts as a Pro-Astrogliogenic Factor and Rescues Cognitive Impairments Induced by Stress Exposure. Cells. 11. PMID 35159199 DOI: 10.3390/cells11030390  0.741
2021 Silveira-Rosa T, Mateus-Pinheiro A, Correia JS, Silva JM, Martins-Macedo J, Araújo B, Machado-Santos AR, Alves ND, Silva M, Loureiro-Campos E, Sotiropoulos I, Bessa JM, Rodrigues AJ, Sousa N, Patrício P, et al. Suppression of adult cytogenesis in the rat brain leads to sex-differentiated disruption of the HPA axis activity. Cell Proliferation. e13165. PMID 34970787 DOI: 10.1111/cpr.13165  0.722
2021 Lima S, Sousa N, Patrício P, Pinto L. The underestimated sex: A review on female animal models of depression. Neuroscience and Biobehavioral Reviews. 133: 104498. PMID 34953920 DOI: 10.1016/j.neubiorev.2021.12.021  0.562
2021 Loureiro-Campos E, Mateus-Pinheiro A, Patrício P, Soares-Cunha C, Silva J, Sardinha VM, Mendes-Pinheiro B, Silveira-Rosa T, Domingues AV, Rodrigues AJ, Oliveira J, Sousa N, Alves ND, Pinto L. Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods. Elife. 10. PMID 34859784 DOI: 10.7554/eLife.70685  0.718
2021 Patrício P, Mateus-Pinheiro A, Machado-Santos AR, Alves ND, Correia JS, Morais M, Bessa JM, Rodrigues AJ, Sousa N, Pinto L. Cell Cycle Regulation of Hippocampal Progenitor Cells in Experimental Models of Depression and after Treatment with Fluoxetine. International Journal of Molecular Sciences. 22. PMID 34769232 DOI: 10.3390/ijms222111798  0.726
2021 Mateus-Pinheiro A, Patrício P, Alves ND, Martins-Macedo J, Caetano I, Silveira-Rosa T, Araújo B, Mateus-Pinheiro M, Silva-Correia J, Sardinha VM, Loureiro-Campos E, Rodrigues AJ, Oliveira JF, Bessa JM, Sousa N, et al. Hippocampal cytogenesis abrogation impairs inter-regional communication between the hippocampus and prefrontal cortex and promotes the time-dependent manifestation of emotional and cognitive deficits. Molecular Psychiatry. PMID 34521994 DOI: 10.1038/s41380-021-01287-8  0.745
2021 Coimbra B, Domingues AV, Soares-Cunha C, Correia R, Pinto L, Sousa N, Rodrigues AJ. Laterodorsal tegmentum-ventral tegmental area projections encode positive reinforcement signals. Journal of Neuroscience Research. PMID 34374447 DOI: 10.1002/jnr.24931  0.56
2020 Gomes ED, Ghosh B, Lima R, Goulão M, Moreira-Gomes T, Martins-Macedo J, Urban MW, Wright MC, Gimble JM, Sousa N, Silva NA, Lepore AC, Salgado AJ. Combination of a Gellan Gum-Based Hydrogel With Cell Therapy for the Treatment of Cervical Spinal Cord Injury. Frontiers in Bioengineering and Biotechnology. 8: 984. PMID 32984278 DOI: 10.3389/Fbioe.2020.00984  0.8
2020 Patrício P, Mateus-Pinheiro A, Alves ND, Morais M, Rodrigues AJ, Bessa JM, Sousa N, Pinto L. miR-409 and miR-411 Modulation in the Adult Brain of a Rat Model of Depression and After Fluoxetine Treatment. Frontiers in Behavioral Neuroscience. 14: 136. PMID 32848656 DOI: 10.3389/Fnbeh.2020.00136  0.724
2020 Azevedo O, Marques N, Reis L, Cruz I, Craveiro N, Antunes H, Lourenço C, Gomes R, Guerreiro RA, Faria R, Sá F, Lima R, Gaspar P, Faria R, Miltenberger-Miltenyi G, ... Sousa N, et al. Predictors of Fabry disease in patients with hypertrophic cardiomyopathy: How to guide the diagnostic strategy? American Heart Journal. 226: 114-126. PMID 32531501 DOI: 10.1016/J.Ahj.2020.04.006  0.526
2020 Monteiro-Fernandes D, Sousa N, Almeida OFX, Sotiropoulos I. Sex Hormone Depletion Augments Glucocorticoid Induction of Tau Hyperphosphorylation in Male Rat Brain. Neuroscience. PMID 32512138 DOI: 10.1016/J.Neuroscience.2020.05.049  0.303
2020 Guerra-Gomes S, Cunha-Garcia D, Marques Nascimento DS, Duarte-Silva S, Loureiro-Campos E, Morais Sardinha V, Viana JF, Sousa N, Maciel P, Pinto L, Oliveira JF. IP R2 null mice display a normal acquisition of somatic and neurological development milestones. The European Journal of Neuroscience. PMID 32166822 DOI: 10.1111/Ejn.14724  0.584
2020 Antunes C, Da Silva JD, Guerra-Gomes S, Alves ND, Ferreira F, Loureiro-Campos E, Branco MR, Sousa N, Reik W, Pinto L, Marques CJ. Tet3 ablation in adult brain neurons increases anxiety-like behavior and regulates cognitive function in mice. Molecular Psychiatry. PMID 32103150 DOI: 10.1038/S41380-020-0695-7  0.748
2020 Soares da Costa D, Sousa JC, Dá Mesquita S, Petkova-Yankova NI, Marques F, Reis RL, Sousa N, Pashkuleva I. Bioorthogonal Labeling Reveals Different Expression of Glycans in Mouse Hippocampal Neuron Cultures during Their Development. Molecules (Basel, Switzerland). 25. PMID 32059500 DOI: 10.3390/Molecules25040795  0.463
2020 Castelhano-Carlos MJ, Aslani S, Sousa N. The impact of physical enrichment in the structure of the medial prefrontal cortex and nucleus accumbens of the adult male rat brain. Neuroscience. 454: 51-60. PMID 32058067 DOI: 10.1016/J.Neuroscience.2020.01.040  0.326
2020 Cunha AM, Teixeira FG, Guimarães MR, Esteves M, Pereira-Mendes J, Soares AR, Almeida A, Sousa N, Salgado AJ, Leite-Almeida H. Unilateral accumbal dopamine depletion affects decision-making in a side-specific manner. Experimental Neurology. 327: 113221. PMID 32027930 DOI: 10.1016/J.Expneurol.2020.113221  0.537
2020 Cristóvão AC, Campos FL, Je G, Esteves M, Guhathakurta S, Yang L, Beal MF, Fonseca BM, Salgado AJ, Queiroz J, Sousa N, Bernardino L, Alves G, Yoon KS, Kim YS. Characterization of a Parkinson's disease rat model using an upgraded paraquat exposure paradigm. The European Journal of Neuroscience. PMID 31958881 DOI: 10.1111/Ejn.14683  0.54
2020 Santiago M, Antunes C, Guedes M, Iacovino M, Kyba M, Reik W, Sousa N, Pinto L, Branco MR, Marques CJ. Correction to: Tet3 regulates cellular identity and DNA methylation in neural progenitor cells. Cellular and Molecular Life Sciences : Cmls. PMID 31919574 DOI: 10.1007/S00018-019-03443-4  0.585
2019 Machado-Santos AR, Alves ND, Araújo B, Correia JS, Patrício P, Mateus-Pinheiro A, Loureiro-Campos E, Bessa JM, Sousa N, Pinto L. Astrocytic plasticity at the dorsal dentate gyrus on an animal model of recurrent depression. Neuroscience. PMID 31747562 DOI: 10.1016/J.Neuroscience.2019.10.032  0.758
2019 Santiago M, Antunes C, Guedes M, Iacovino M, Kyba M, Reik W, Sousa N, Pinto L, Branco MR, Marques CJ. Tet3 regulates cellular identity and DNA methylation in neural progenitor cells. Cellular and Molecular Life Sciences : Cmls. PMID 31646359 DOI: 10.1007/S00018-019-03335-7  0.617
2019 Antunes C, Sousa N, Pinto L, Marques CJ. TET enzymes in neurophysiology and brain function. Neuroscience and Biobehavioral Reviews. PMID 31078565 DOI: 10.1016/J.Neubiorev.2019.05.006  0.606
2019 Miranda AM, Bravo FV, Chan RB, Sousa N, Di Paolo G, Oliveira TG. Differential lipid composition and regulation along the hippocampal longitudinal axis. Translational Psychiatry. 9: 144. PMID 31028243 DOI: 10.1038/S41398-019-0478-6  0.317
2019 Dioli C, Patrício P, Sousa N, Kokras N, Dalla C, Guerreiro S, Santos-Silva MA, Rego AC, Pinto L, Ferreiro E, Sotiropoulos I. Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields. Translational Psychiatry. 9: 143. PMID 31028242 DOI: 10.1038/S41398-019-0477-7  0.627
2019 Magalhães R, Novais A, Barrière DA, Marques P, Marques F, Sousa JC, Cerqueira J, Cachia A, Jay TM, Bottlaender M, Sousa N, Mériaux S, Boumezbeur F. A resting-state functional MR Imaging and Spectroscopy Study of the Dorsal Hippocampus in the Chronic Unpredictable Stress Rat Model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30804096 DOI: 10.1523/Jneurosci.2192-18.2019  0.313
2019 Ferreira AC, Novais A, Sousa N, Sousa JC, Marques F. Voluntary running rescues the defective hippocampal neurogenesis and behaviour observed in lipocalin 2-null mice. Scientific Reports. 9: 1649. PMID 30733506 DOI: 10.1038/S41598-018-38140-Y  0.333
2018 Novais A, Silva A, Ferreira AC, Falcão AM, Sousa N, Palha JA, Marques F, Sousa JC. Adult Hippocampal Neurogenesis Modulation by the Membrane-Associated Progesterone Receptor Family Member Neudesin. Frontiers in Cellular Neuroscience. 12: 463. PMID 30534059 DOI: 10.3389/Fncel.2018.00463  0.317
2018 Soares AR, Esteves M, Moreira PS, Cunha AM, Guimarães MR, Carvalho MM, Raposo-Lima C, Morgado P, Carvalho AF, Coimbra B, Melo A, Rodrigues AJ, Salgado AJ, Pêgo JM, Cerqueira JJ, ... ... Sousa N, et al. Trait determinants of impulsive behavior: a comprehensive analysis of 188 rats. Scientific Reports. 8: 17666. PMID 30518850 DOI: 10.1038/S41598-018-35537-7  0.721
2018 Kokras N, Sotiropoulos I, Besinis D, Tzouveka EL, Almeida OFX, Sousa N, Dalla C. Neuroplasticity-related correlates of environmental enrichment combined with physical activity differ between the sexes. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 30497839 DOI: 10.1016/J.Euroneuro.2018.11.1107  0.309
2018 Duarte JM, Gaspar R, Caetano L, Patrício P, Soares-Cunha C, Mateus-Pinheiro A, Alves ND, Santos AR, Ferreira SG, Sardinha V, Oliveira JF, Fontes-Ribeiro C, Sousa N, Cunha RA, Ambrósio AF, et al. Region-specific control of microglia by adenosine A receptors: uncoupling anxiety and associated cognitive deficits in female rats. Glia. PMID 30461068 DOI: 10.1002/Glia.23476  0.744
2018 Guerra-Gomes S, Viana JF, Nascimento DSM, Correia JS, Sardinha VM, Caetano I, Sousa N, Pinto L, Oliveira JF. The Role of Astrocytic Calcium Signaling in the Aged Prefrontal Cortex. Frontiers in Cellular Neuroscience. 12: 379. PMID 30455631 DOI: 10.3389/Fncel.2018.00379  0.611
2018 Ferreira AC, Sousa N, Bessa JM, Sousa JC, Marques F. Metabolism and adult neurogenesis: towards an understanding of the role of lipocalin-2 and iron-related oxidative stress. Neuroscience and Biobehavioral Reviews. PMID 30267731 DOI: 10.1016/J.Neubiorev.2018.09.014  0.357
2018 Soares-Cunha C, Coimbra B, Borges S, Domingues AV, Silva D, Sousa N, Rodrigues AJ. Mild Prenatal Stress Causes Emotional and Brain Structural Modifications in Rats of Both Sexes. Frontiers in Behavioral Neuroscience. 12: 129. PMID 30034328 DOI: 10.3389/Fnbeh.2018.00129  0.314
2018 Mateus-Pinheiro A, Alves ND, Sousa N, Pinto L. AP2γ: A New Player on Adult Hippocampal Neurogenesis Regulation. Journal of Experimental Neuroscience. 12: 1179069518766897. PMID 29636632 DOI: 10.1177/1179069518766897  0.744
2018 Gomes ED, Mendes SS, Assunção-Silva RC, Teixeira FG, Pires AO, Anjo SI, Manadas B, Leite-Almeida H, Gimble JM, Sousa N, Lepore AC, Silva NA, Salgado AJ. Co-Transplantation of Adipose tissue-derived Stromal Cells and Olfactory Ensheathing Cells for Spinal Cord Injury Repair. Stem Cells (Dayton, Ohio). PMID 29352743 DOI: 10.1002/Stem.2785  0.8
2018 Teixeira FG, Gago MF, Marques P, Moreira PS, Magalhães R, Sousa N, Salgado AJ. Safinamide: a new hope for Parkinson's disease? Drug Discovery Today. PMID 29339106 DOI: 10.1016/J.Drudis.2018.01.033  0.525
2018 Chowdhury HH, Cerqueira SR, Sousa N, Oliveira JM, Reis RL, Zorec R. The uptake, retention and clearance of drug-loaded dendrimer nanoparticles in astrocytes - electrophysiological quantification. Biomaterials Science. PMID 29336451 DOI: 10.1039/C7Bm00886D  0.774
2017 Guerra-Gomes S, Sousa N, Pinto L, Oliveira JF. Functional Roles of Astrocyte Calcium Elevations: From Synapses to Behavior. Frontiers in Cellular Neuroscience. 11: 427. PMID 29386997 DOI: 10.3389/Fncel.2017.00427  0.597
2017 Magalhães R, Barrière DA, Novais A, Marques F, Marques P, Cerqueira J, Sousa JC, Cachia A, Boumezbeur F, Bottlaender M, Jay TM, Mériaux S, Sousa N. The dynamics of stress: a longitudinal MRI study of rat brain structure and connectome. Molecular Psychiatry. 23: 1998-2006. PMID 29203852 DOI: 10.1038/Mp.2017.244  0.312
2017 Vieira N, Bessa C, Rodrigues AJ, Marques P, Chan FY, de Carvalho AX, Correia-Neves M, Sousa N. Sorting nexin 3 mutation impairs development and neuronal function in Caenorhabditis elegans. Cellular and Molecular Life Sciences : Cmls. PMID 29196797 DOI: 10.1007/S00018-017-2719-2  0.304
2017 Lima R, Monteiro S, Lopes JP, Barradas P, Vasconcelos NL, Gomes ED, Assunção-Silva RC, Teixeira FG, Morais M, Sousa N, Salgado AJ, Silva NA. Systemic Interleukin-4 Administration after Spinal Cord Injury Modulates Inflammation and Promotes Neuroprotection. Pharmaceuticals (Basel, Switzerland). 10. PMID 29064422 DOI: 10.3390/Ph10040083  0.771
2017 Sevivas N, Teixeira FG, Portugal R, Direito-Santos B, Espregueira-Mendes J, Oliveira FJ, Silva RF, Sousa N, Sow WT, Luong N, Ng KW, Salgado AJ. Mesenchymal Stem Cell Secretome Improves Tendon Cell Viability In Vitro and Tendon-Bone Healing In Vivo When a Tissue Engineering Strategy Is Used in a Rat Model of Chronic Massive Rotator Cuff Tear. The American Journal of Sports Medicine. 363546517735850. PMID 29053925 DOI: 10.1177/0363546517735850  0.549
2017 Sardinha VM, Guerra-Gomes S, Caetano I, Tavares G, Martins M, Reis JS, Correia JS, Teixeira-Castro A, Pinto L, Sousa N, Oliveira JF. Astrocytic signaling supports hippocampal-prefrontal theta synchronization and cognitive function. Glia. PMID 28885722 DOI: 10.1002/Glia.23205  0.609
2017 Alves ND, Patrício P, Correia JS, Mateus-Pinheiro A, Machado-Santos AR, Loureiro-Campos E, Morais M, Bessa JM, Sousa N, Pinto L. Chronic stress targets adult neurogenesis preferentially in the suprapyramidal blade of the rat dorsal dentate gyrus. Brain Structure & Function. PMID 28852856 DOI: 10.1007/S00429-017-1490-3  0.761
2017 Carvalho MM, Campos FL, Marques M, Soares-Cunha C, Kokras N, Dalla C, Leite-Almeida H, Sousa N, Salgado AJ. Effect of Levodopa on Reward and Impulsivity in a Rat Model of Parkinson's Disease. Frontiers in Behavioral Neuroscience. 11: 145. PMID 28848409 DOI: 10.3389/Fnbeh.2017.00145  0.721
2017 Sevivas N, Ferreira N, Andrade R, Moreira P, Portugal R, Alves D, Vieira da Silva M, Sousa N, Salgado AJ, Espregueira-Mendes J. Reverse shoulder arthroplasty for irreparable massive rotator cuff tears: a systematic review with meta-analysis and meta-regression. Journal of Shoulder and Elbow Surgery. PMID 28684233 DOI: 10.1016/J.Jse.2017.03.039  0.492
2017 Martins LF, Costa RO, Pedro JR, Aguiar P, Serra SC, Teixeira FG, Sousa N, Salgado AJ, Almeida RD. Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF. Scientific Reports. 7: 4153. PMID 28646200 DOI: 10.1038/S41598-017-03592-1  0.54
2017 Cengiz IF, Pereira H, Pêgo JM, Sousa N, Espregueira-Mendes J, Oliveira JM, Reis RL. Segmental and regional quantification of 3D cellular density of human meniscus from osteoarthritic knee. Journal of Tissue Engineering and Regenerative Medicine. 11: 1844-1852. PMID 28586544 DOI: 10.1002/Term.2082  0.422
2017 Morais M, Patrício P, Mateus-Pinheiro A, Alves ND, Machado-Santos AR, Correia JS, Pereira J, Pinto L, Sousa N, Bessa JM. The modulation of adult neuroplasticity is involved in the mood-improving actions of atypical antipsychotics in an animal model of depression. Translational Psychiatry. 7: e1146. PMID 28585931 DOI: 10.1038/Tp.2017.120  0.347
2017 Dioli C, Patrício P, Trindade R, Pinto LG, Silva JM, Morais M, Ferreiro E, Borges S, Mateus-Pinheiro A, Rodrigues AJ, Sousa N, Bessa JM, Pinto L, Sotiropoulos I. Tau-dependent suppression of adult neurogenesis in the stressed hippocampus. Molecular Psychiatry. PMID 28555078 DOI: 10.1016/S0924-977X(17)31043-X  0.323
2017 Ferreira AC, Santos T, Sampaio-Marques B, Novais A, Mesquita SD, Ludovico P, Bernardino L, Correia-Neves M, Sousa N, Palha JA, Sousa JC, Marques F. Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours. Molecular Psychiatry. PMID 28485407 DOI: 10.1038/Mp.2017.95  0.336
2017 Pires AO, Teixeira FG, Mendes-Pinheiro B, Serra SC, Sousa N, Salgado AJ. Old and New Challenges in Parkinson's Disease Therapeutics. Progress in Neurobiology. PMID 28457671 DOI: 10.1016/J.Pneurobio.2017.04.006  0.526
2017 Kafetzopoulos V, Kokras N, Sotiropoulos I, Oliveira JF, Leite-Almeida H, Vasalou A, Sardinha VM, Papadopoulou-Daifoti Z, Almeida OFX, Antoniou K, Sousa N, Dalla C. The nucleus reuniens: a key node in the neurocircuitry of stress and depression. Molecular Psychiatry. 23: 579-586. PMID 28397837 DOI: 10.1038/Mp.2017.55  0.301
2017 Alves ND, Correia JS, Patrício P, Mateus-Pinheiro A, Machado-Santos AR, Loureiro-Campos E, Morais M, Bessa JM, Sousa N, Pinto L. Adult hippocampal neuroplasticity triggers susceptibility to recurrent depression. Translational Psychiatry. 7: e1058. PMID 28291258 DOI: 10.1038/Tp.2017.29  0.323
2017 Teixeira FG, Carvalho MM, Panchalingam KM, Rodrigues AJ, Mendes-Pinheiro B, Anjo S, Manadas B, Behie LA, Sousa N, Salgado AJ. Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal Behavior in a Rat Model of Parkinson's Disease. Stem Cells Translational Medicine. 6: 634-646. PMID 28191785 DOI: 10.5966/Sctm.2016-0071  0.754
2017 Yu S, Zutshi I, Stoffel R, Zhang J, Ventura-Silva AP, Sousa N, Costa PS, Holsboer F, Patchev A, Almeida OF. Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool. Translational Psychiatry. 7: e990. PMID 28045461 DOI: 10.1038/Tp.2016.255  0.349
2017 Mendes-Pinheiro B, Teixeira F, Anjo S, Manadas B, Behie L, Sousa N, Salgado A. Mesenchymal stem cells secretome: a new therapeutic tool for Parkinson’s disease regenerative medicine? European Neuropsychopharmacology. 27: S687-S688. DOI: 10.1016/S0924-977X(17)31277-4  0.536
2016 Jacinto LR, Mata R, Novais A, Marques F, Sousa N. The habenula as a critical node in chronic stress-related anxiety. Experimental Neurology. PMID 27940019 DOI: 10.1016/J.Expneurol.2016.12.003  0.333
2016 Melo A, Leite-Almeida H, Ferreira C, Sousa N, Pêgo JM. Exposure to Ketamine Anesthesia Affects Rat Impulsive Behavior. Frontiers in Behavioral Neuroscience. 10: 226. PMID 27932959 DOI: 10.3389/Fnbeh.2016.00226  0.312
2016 Mateus-Pinheiro A, Alves ND, Patrício P, Machado-Santos AR, Loureiro-Campos E, Silva JM, Sardinha VM, Reis J, Schorle H, Oliveira JF, Ninkovic J, Sousa N, Pinto L. AP2γ controls adult hippocampal neurogenesis and modulates cognitive, but not anxiety or depressive-like behavior. Molecular Psychiatry. PMID 27777416 DOI: 10.1038/Mp.2016.169  0.348
2016 Caetano L, Pinheiro H, Patrício P, Mateus-Pinheiro A, Alves ND, Coimbra B, Baptista FI, Henriques SN, Cunha C, Santos AR, Ferreira SG, Sardinha VM, Oliveira JF, Ambrósio AF, Sousa N, et al. Adenosine A2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety. Molecular Psychiatry. PMID 27725661 DOI: 10.1038/Mp.2016.173  0.322
2016 Teixeira FG, Carvalho MM, Panchalingam KM, Rodrigues AJ, Mendes-Pinheiro B, Anjo S, Manadas B, Behie LA, Sousa N, Salgado AJ. Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal Behavior in a Rat Model of Parkinson's Disease. Stem Cells Translational Medicine. PMID 27659216 DOI: 10.5966/sctm.2016-0071  0.737
2016 Duarte AR, Maniglio D, Sousa N, Mano JF, Reis RL, Migliaresi C. From honeycomb- to microsphere-patterned surfaces of poly(lactic acid) and a starch-poly(lactic acid) blend via the breath figure method. Journal of Applied Biomaterials & Functional Materials. 0. PMID 27647384 DOI: 10.5301/Jabfm.5000281  0.336
2016 Gomes ED, Mendes SS, Leite-Almeida H, Gimble JM, Tam RY, Shoichet MS, Sousa N, Silva NA, Salgado AJ. Combination of a peptide-modified gellan gum hydrogel with cell therapy in a lumbar spinal cord injury animal model. Biomaterials. 105: 38-51. PMID 27505621 DOI: 10.1016/J.Biomaterials.2016.07.019  0.804
2016 Sevivas N, Teixeira FG, Portugal R, Araújo L, Carriço LF, Ferreira N, Vieira da Silva M, Espregueira-Mendes J, Anjo S, Manadas B, Sousa N, Salgado AJ. Mesenchymal Stem Cell Secretome: A Potential Tool for the Prevention of Muscle Degenerative Changes Associated With Chronic Rotator Cuff Tears. The American Journal of Sports Medicine. PMID 27501832 DOI: 10.1016/J.Arthro.2017.08.034  0.549
2016 Oliveira JF, Gomes CA, Vaz SH, Sousa N, Pinto L. Editorial: Glial Plasticity in Depression. Frontiers in Cellular Neuroscience. 10: 163. PMID 27378858 DOI: 10.3389/Fncel.2016.00163  0.621
2016 Soares-Cunha C, Coimbra B, David-Pereira A, Borges S, Pinto L, Costa P, Sousa N, Rodrigues AJ. Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation. Nature Communications. 7: 11829. PMID 27337658 DOI: 10.1038/Ncomms11829  0.599
2016 Teixeira FG, Panchalingam KM, Assunção-Silva R, Serra SC, Mendes-Pinheiro B, Patrício P, Jung S, Anjo SI, Manadas B, Pinto L, Sousa N, Behie LA, Salgado AJ. Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation. Scientific Reports. 6: 27791. PMID 27301770 DOI: 10.1038/Srep27791  0.724
2016 Pires A, Pinheiro B, Teixeira FG, Anjo S, Samy S, Gomes E, Serra S, Silva NA, Manadas B, Sousa N, Salgado AJ. Unveiling the Differences of Secretome of Human Bone Marrow Mesenchymal Stem Cells, Adipose Tissue derived Stem Cells and Human Umbilical Cord Perivascular Cells: A Proteomic Analysis. Stem Cells and Development. PMID 27226274 DOI: 10.1089/scd.2016.0048  0.751
2016 Teixeira FG, Vasconcelos NL, Gomes ED, Marques F, Sousa JC, Sousa N, Silva NA, Assunção-Silva R, Lima R, Salgado AJ. Bioengineered cell culture systems of central nervous system injury and disease. Drug Discovery Today. PMID 27132519 DOI: 10.1016/J.Drudis.2016.04.020  0.781
2016 Vasconcelos NL, Gomes ED, Oliveira EP, Silva CJ, Lima R, Sousa N, Salgado AJ, Silva NA. Combing neuroprotective agents: effect of riluzole and magnesium in a rat model of thoracic spinal cord injury. The Spine Journal : Official Journal of the North American Spine Society. PMID 27109831 DOI: 10.1016/J.Spinee.2016.04.013  0.777
2016 Lopes S, Teplytska L, Vaz-Silva J, Dioli C, Trindade R, Morais M, Webhofer C, Maccarrone G, Almeida OF, Turck CW, Sousa N, Sotiropoulos I, Filiou MD. Tau Deletion Prevents Stress-Induced Dendritic Atrophy in Prefrontal Cortex: Role of Synaptic Mitochondria. Cerebral Cortex (New York, N.Y. : 1991). PMID 27073221 DOI: 10.1093/Cercor/Bhw057  0.306
2016 Vyas S, Rodrigues AJ, Silva JM, Tronche F, Almeida OF, Sousa N, Sotiropoulos I. Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration. Neural Plasticity. 2016: 6391686. PMID 27034847 DOI: 10.1155/2016/6391686  0.309
2016 Cerqueira SR, Oliveira JM, Silva NA, Leite-Almeida H, Ribeiro-Samy S, Almeida A, Mano JF, Sousa N, Salgado AJ, Reis RL. Microglia Response and In Vivo Therapeutic Potential of Methylprednisolone-Loaded Dendrimer Nanoparticles in Spinal Cord Injury. Small (Weinheim An Der Bergstrasse, Germany). 12: 972. PMID 26890375 DOI: 10.1002/smll.201503492  0.778
2016 Cerqueira SR, Silva BL, Oliveira JM, Mano JF, Sousa N, Salgado AJ, Reis RL. Multifunctionalized CMCht/PAMAM Dendrimer Nanoparticles Modulate the Cellular Uptake by Astrocytes and Oligodendrocytes in Primary Cultures of Glial Cells. Macromolecular Bioscience. 16: 299. PMID 26864734 DOI: 10.1002/Mabi.201500419  0.778
2016 Patricio P, Mateus-Pinheiro A, Machado-Santos AR, Alves ND, Morais M, Bessa JM, Sousa N, Pinto L. Cell cycle regulation of the hippocampal progenitor cells in an animal model of depression and after fluoxetine treatment European Neuropsychopharmacology. 26. DOI: 10.1016/S0924-977X(16)31475-4  0.313
2016 Fraga J, Silva N, Lourenço A, Gonçalves V, Neves N, Reis R, Rodrigues A, Manadas B, Sousa N, Salgado A. Corrigendum to ‘Unveiling the effects of the secretome of mesenchymal progenitors from the umbilical cord in different neuronal cell populations’ [Biochimie 95–12 (2013) 2297–2303] Biochimie. 121: 336. DOI: 10.1016/J.Biochi.2015.11.025  0.716
2015 Assunção-Silva RC, Oliveira CC, Ziv-Polat O, Gomes ED, Sahar A, Sousa N, Silva NA, Salgado AJ. Induction of neurite outgrowth in 3D hydrogel-based environments. Biomedical Materials (Bristol, England). 10: 051001. PMID 26480959 DOI: 10.1088/1748-6041/10/5/051001  0.752
2015 Canha-Gouveia A, Rita Costa-Pinto A, Martins AM, Silva NA, Faria S, Sousa RA, Salgado AJ, Sousa N, Reis RL, Neves NM. Hierarchical scaffolds enhance osteogenic differentiation of human Wharton's jelly derived stem cells. Biofabrication. 7: 035009. PMID 26335618 DOI: 10.1088/1758-5090/7/3/035009  0.699
2015 Oliveira JF, Sardinha VM, Guerra-Gomes S, Araque A, Sousa N. Do stars govern our actions? Astrocyte involvement in rodent behavior. Trends in Neurosciences. 38: 535-49. PMID 26316036 DOI: 10.1016/J.Tins.2015.07.006  0.313
2015 Salgado AJ, Sousa JC, Costa BM, Pires AO, Mateus-Pinheiro A, Teixeira FG, Pinto L, Sousa N. Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities. Frontiers in Cellular Neuroscience. 9: 249. PMID 26217178 DOI: 10.3389/Fncel.2015.00249  0.716
2015 Teixeira FG, Panchalingam KM, Anjo SI, Manadas B, Pereira R, Sousa N, Salgado AJ, Behie LA. Do hypoxia/normoxia culturing conditions change the neuroregulatory profile of Wharton Jelly mesenchymal stem cell secretome? Stem Cell Research & Therapy. 6: 133. PMID 26204925 DOI: 10.1186/S13287-015-0124-Z  0.565
2015 Ferreira AC, Dá Mesquita S, Sousa JC, Correia-Neves M, Sousa N, Palha JA, Marques F. From the periphery to the brain: Lipocalin-2, a friend or foe? Progress in Neurobiology. 131: 120-36. PMID 26159707 DOI: 10.1016/J.Pneurobio.2015.06.005  0.329
2015 Assunção-Silva RC, Gomes ED, Sousa N, Silva NA, Salgado AJ. Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration. Stem Cells International. 2015: 948040. PMID 26124844 DOI: 10.1155/2015/948040  0.77
2015 Pojo M, Gonçalves CS, Xavier-Magalhães A, Oliveira AI, Gonçalves T, Correia S, Rodrigues AJ, Costa S, Pinto L, Pinto AA, Lopes JM, Reis RM, Rocha M, Sousa N, Costa BM. A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. Oncotarget. 6: 7657-74. PMID 25762636 DOI: 10.18632/Oncotarget.3150  0.612
2015 Oliveira TG, Chan RB, Bravo FV, Miranda A, Silva RR, Zhou B, Marques F, Pinto V, Cerqueira JJ, Di Paolo G, Sousa N. The impact of chronic stress on the rat brain lipidome. Molecular Psychiatry. PMID 25754084 DOI: 10.1038/Mp.2015.14  0.308
2015 Lamas NJ, Serra SC, Salgado AJ, Sousa N. Failure of Y-27632 to improve the culture of adult human adipose-derived stem cells. Stem Cells and Cloning : Advances and Applications. 8: 15-26. PMID 25609984 DOI: 10.2147/SCCAA.S66597  0.5
2015 Teixeira FG, Carvalho MM, Neves-Carvalho A, Panchalingam KM, Behie LA, Pinto L, Sousa N, Salgado AJ. Secretome of mesenchymal progenitors from the umbilical cord acts as modulator of neural/glial proliferation and differentiation. Stem Cell Reviews. 11: 288-97. PMID 25420577 DOI: 10.1007/S12015-014-9576-2  0.803
2015 Patrício P, Mateus-Pinheiro A, Irmler M, Alves ND, Machado-Santos AR, Morais M, Correia JS, Korostynski M, Piechota M, Stoffel R, Beckers J, Bessa JM, Almeida OF, Sousa N, Pinto L. Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 338-49. PMID 25035085 DOI: 10.1038/Npp.2014.176  0.747
2015 Cengiz IF, Pereira H, Pêgo JM, Sousa N, Espregueira-Mendes J, Oliveira JM, Reis RL. Segmental and regional quantification of 3D cellular density of human meniscus from osteoarthritic knee Journal of Tissue Engineering and Regenerative Medicine. DOI: 10.1002/term.2082  0.332
2014 Soares-Cunha C, Coimbra B, Borges S, Carvalho MM, Rodrigues AJ, Sousa N. The motivational drive to natural rewards is modulated by prenatal glucocorticoid exposure. Translational Psychiatry. 4: e397. PMID 25928947 DOI: 10.1038/Tp.2014.45  0.652
2014 Sevivas N, Serra SC, Portugal R, Teixeira FG, Carvalho MM, Silva N, Espregueira-Mendes J, Sousa N, Salgado AJ. Animal model for chronic massive rotator cuff tear: behavioural and histologic analysis Knee Surgery, Sports Traumatology, Arthroscopy. 23: 608-618. PMID 25416674 DOI: 10.1007/S00167-014-3441-3  0.763
2014 Morais M, Santos PA, Mateus-Pinheiro A, Patrício P, Pinto L, Sousa N, Pedroso P, Almeida S, Filipe A, Bessa JM. The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition. Journal of Psychopharmacology (Oxford, England). 28: 1178-83. PMID 25315831 DOI: 10.1177/0269881114553646  0.618
2014 Pires AO, Neves-Carvalho A, Sousa N, Salgado AJ. The Secretome of Bone Marrow and Wharton Jelly Derived Mesenchymal Stem Cells Induces Differentiation and Neurite Outgrowth in SH-SY5Y Cells. Stem Cells International. 2014: 438352. PMID 25132857 DOI: 10.1155/2014/438352  0.582
2014 Aslani S, Harb MR, Costa PS, Almeida OF, Sousa N, Palha JA. Day and night: diurnal phase influences the response to chronic mild stress. Frontiers in Behavioral Neuroscience. 8: 82. PMID 24672446 DOI: 10.3389/Fnbeh.2014.00082  0.301
2014 Mateus-Pinheiro A, Patrício P, Alves ND, Machado-Santos AR, Morais M, Bessa JM, Sousa N, Pinto L. The Sweet Drive Test: refining phenotypic characterization of anhedonic behavior in rodents. Frontiers in Behavioral Neuroscience. 8: 74. PMID 24639637 DOI: 10.3389/Fnbeh.2014.00074  0.727
2014 Wrobel S, Serra SC, Ribeiro-Samy S, Sousa N, Heimann C, Barwig C, Grothe C, Salgado AJ, Haastert-Talini K. In vitro evaluation of cell-seeded chitosan films for peripheral nerve tissue engineering. Tissue Engineering. Part A. 20: 2339-49. PMID 24606318 DOI: 10.1089/Ten.Tea.2013.0621  0.536
2014 Lima A, Sardinha VM, Oliveira AF, Reis M, Mota C, Silva MA, Marques F, Cerqueira JJ, Pinto L, Sousa N, Oliveira JF. Astrocyte pathology in the prefrontal cortex impairs the cognitive function of rats. Molecular Psychiatry. 19: 834-41. PMID 24419043 DOI: 10.1038/Mp.2013.182  0.345
2014 Lucassen PJ, Pruessner J, Sousa N, Almeida OF, Van Dam AM, Rajkowska G, Swaab DF, Czéh B. Neuropathology of stress. Acta Neuropathologica. 127: 109-35. PMID 24318124 DOI: 10.1007/S00401-013-1223-5  0.302
2014 Silva NA, Sousa N, Reis RL, Salgado AJ. From basics to clinical: a comprehensive review on spinal cord injury. Progress in Neurobiology. 114: 25-57. PMID 24269804 DOI: 10.1016/J.Pneurobio.2013.11.002  0.714
2013 Borges S, Coimbra B, Soares-Cunha C, Ventura-Silva AP, Pinto L, Carvalho MM, Pêgo JM, Rodrigues AJ, Sousa N. Glucocorticoid programing of the mesopontine cholinergic system. Frontiers in Endocrinology. 4: 190. PMID 24379803 DOI: 10.3389/Fendo.2013.00190  0.748
2013 Campos FL, Carvalho MM, Cristovão AC, Je G, Baltazar G, Salgado AJ, Kim YS, Sousa N. Rodent models of Parkinson's disease: beyond the motor symptomatology. Frontiers in Behavioral Neuroscience. 7: 175. PMID 24324416 DOI: 10.3389/Fnbeh.2013.00175  0.725
2013 Jacinto LR, Reis JS, Dias NS, Cerqueira JJ, Correia JH, Sousa N. Stress affects theta activity in limbic networks and impairs novelty-induced exploration and familiarization. Frontiers in Behavioral Neuroscience. 7: 127. PMID 24137113 DOI: 10.3389/Fnbeh.2013.00127  0.322
2013 Salgado AJ, Oliveira JM, Martins A, Teixeira FG, Silva NA, Neves NM, Sousa N, Reis RL. Tissue engineering and regenerative medicine: past, present, and future. International Review of Neurobiology. 108: 1-33. PMID 24083429 DOI: 10.1016/B978-0-12-410499-0.00001-0  0.694
2013 Novais A, Ferreira AC, Marques F, Pêgo JM, Cerqueira JJ, David-Pereira A, Campos FL, Dalla C, Kokras N, Sousa N, Palha JA, Sousa JC. Neudesin is involved in anxiety behavior: structural and neurochemical correlates. Frontiers in Behavioral Neuroscience. 7: 119. PMID 24058337 DOI: 10.3389/Fnbeh.2013.00119  0.328
2013 Haastert-Talini K, Geuna S, Dahlin LB, Meyer C, Stenberg L, Freier T, Heimann C, Barwig C, Pinto LF, Raimondo S, Gambarotta G, Samy SR, Sousa N, Salgado AJ, Ratzka A, et al. Chitosan tubes of varying degrees of acetylation for bridging peripheral nerve defects. Biomaterials. 34: 9886-904. PMID 24050875 DOI: 10.1016/J.Biomaterials.2013.08.074  0.498
2013 Ribeiro-Samy S, Silva NA, Correlo VM, Fraga JS, Pinto L, Teixeira-Castro A, Leite-Almeida H, Almeida A, Gimble JM, Sousa N, Salgado AJ, Reis RL. Development and characterization of a PHB-HV-based 3D scaffold for a tissue engineering and cell-therapy combinatorial approach for spinal cord injury regeneration. Macromolecular Bioscience. 13: 1576-92. PMID 24038969 DOI: 10.1002/Mabi.201300178  0.789
2013 Silva NA, Moreira J, Ribeiro-Samy S, Gomes ED, Tam RY, Shoichet MS, Reis RL, Sousa N, Salgado AJ. Modulation of bone marrow mesenchymal stem cell secretome by ECM-like hydrogels. Biochimie. 95: 2314-9. PMID 23994751 DOI: 10.1016/J.Biochi.2013.08.016  0.792
2013 Falcão AM, Palha JA, Ferreira AC, Marques F, Sousa N, Sousa JC. Unbiased stereological method to assess proliferation throughout the subependymal zone. Methods in Molecular Biology (Clifton, N.J.). 1035: 141-52. PMID 23959988 DOI: 10.1007/978-1-62703-508-8_12  0.328
2013 Ferreira AC, Pinto V, Dá Mesquita S, Novais A, Sousa JC, Correia-Neves M, Sousa N, Palha JA, Marques F. Lipocalin-2 is involved in emotional behaviors and cognitive function. Frontiers in Cellular Neuroscience. 7: 122. PMID 23908604 DOI: 10.3389/Fncel.2013.00122  0.326
2013 Fraga JS, Silva NA, Lourenço AS, Gonçalves V, Neves NM, Reis RL, Rodrigues AJ, Manadas B, Sousa N, Salgado AJ. Unveiling the effects of the secretome of mesenchymal progenitors from the umbilical cord in different neuronal cell populations. Biochimie. 95: 2297-303. PMID 23851197 DOI: 10.1016/J.Biochi.2013.06.028  0.72
2013 Bessa JM, Morais M, Marques F, Pinto L, Palha JA, Almeida OF, Sousa N. Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens. Translational Psychiatry. 3: e266. PMID 23736119 DOI: 10.1038/Tp.2013.39  0.35
2013 Mateus-Pinheiro A, Patrício P, Bessa JM, Sousa N, Pinto L. Cell genesis and dendritic plasticity: a neuroplastic pas de deux in the onset and remission from depression. Molecular Psychiatry. 18: 748-50. PMID 23711984 DOI: 10.1038/Mp.2013.56  0.309
2013 Ventura-Silva AP, Melo A, Ferreira AC, Carvalho MM, Campos FL, Sousa N, Pêgo JM. Excitotoxic lesions in the central nucleus of the amygdala attenuate stress-induced anxiety behavior. Frontiers in Behavioral Neuroscience. 7: 32. PMID 23626528 DOI: 10.3389/Fnbeh.2013.00032  0.659
2013 Carvalho MM, Campos FL, Coimbra B, Pêgo JM, Rodrigues C, Lima R, Rodrigues AJ, Sousa N, Salgado AJ. Behavioral characterization of the 6-hydroxidopamine model of Parkinson's disease and pharmacological rescuing of non-motor deficits. Molecular Neurodegeneration. 8: 14. PMID 23621954 DOI: 10.1186/1750-1326-8-14  0.764
2013 Patrício P, Mateus-Pinheiro A, Sousa N, Pinto L. Re-cycling paradigms: cell cycle regulation in adult hippocampal neurogenesis and implications for depression. Molecular Neurobiology. 48: 84-96. PMID 23471746 DOI: 10.1007/S12035-013-8422-X  0.622
2013 Teixeira FG, Carvalho MM, Sousa N, Salgado AJ. Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration? Cellular and Molecular Life Sciences : Cmls. 70: 3871-82. PMID 23456256 DOI: 10.1007/S00018-013-1290-8  0.751
2013 Mateus-Pinheiro A, Pinto L, Bessa JM, Morais M, Alves ND, Monteiro S, Patrício P, Almeida OF, Sousa N. Sustained remission from depressive-like behavior depends on hippocampal neurogenesis. Translational Psychiatry. 3: e210. PMID 23321807 DOI: 10.1038/Tp.2012.141  0.308
2013 Silva NA, Gimble JM, Sousa N, Reis RL, Salgado AJ. Combining adult stem cells and olfactory ensheathing cells: the secretome effect. Stem Cells and Development. 22: 1232-40. PMID 23316915 DOI: 10.1089/Scd.2012.0524  0.725
2013 Lopes A, Torres DB, Rodrigues AJ, Cerqueira J, Pêgo JM, Sousa N, Gontijo JAR, Boer PA. Gestational protein restriction induces CA3 dendritic atrophy in dorsal hippocampal neurons but does not alter learning and memory performance in adult offspring International Journal of Developmental Neuroscience. 31: 151-156. PMID 23280060 DOI: 10.1016/J.Ijdevneu.2012.12.003  0.301
2013 Cerqueira SR, Oliveira JM, Silva NA, Leite-Almeida H, Ribeiro-Samy S, Almeida A, Mano JF, Sousa N, Salgado AJ, Reis RL. Microglia response and in vivo therapeutic potential of methylprednisolone-loaded dendrimer nanoparticles in spinal cord injury. Small (Weinheim An Der Bergstrasse, Germany). 9: 738-49. PMID 23161735 DOI: 10.1002/Smll.201201888  0.785
2013 Silva NA, Sousa RA, Fraga JS, Fontes M, Leite-Almeida H, Cerqueira R, Almeida A, Sousa N, Reis RL, Salgado AJ. Benefits of spine stabilization with biodegradable scaffolds in spinal cord injured rats. Tissue Engineering. Part C, Methods. 19: 101-8. PMID 22779715 DOI: 10.1089/Ten.Tec.2012.0264  0.764
2013 Pojo M, Cerqueira SR, Mota T, Xavier-Magalhães A, Ribeiro-Samy S, Mano JF, Oliveira JM, Reis RL, Sousa N, Costa BM, Salgado AJ. In vitro evaluation of the cytotoxicity and cellular uptake of CMCht/PAMAM dendrimer nanoparticles by glioblastoma cell models Journal of Nanoparticle Research. 15. DOI: 10.1007/S11051-013-1621-6  0.778
2012 Sousa N, Almeida OF. Disconnection and reconnection: the morphological basis of (mal)adaptation to stress. Trends in Neurosciences. 35: 742-51. PMID 23000140 DOI: 10.1016/J.Tins.2012.08.006  0.316
2012 Ventura-Silva AP, Pêgo JM, Sousa JC, Marques AR, Rodrigues AJ, Marques F, Cerqueira JJ, Almeida OF, Sousa N. Stress shifts the response of the bed nucleus of the stria terminalis to an anxiogenic mode. The European Journal of Neuroscience. 36: 3396-406. PMID 22928804 DOI: 10.1111/J.1460-9568.2012.08262.X  0.301
2012 Falcão AM, Marques F, Novais A, Sousa N, Palha JA, Sousa JC. The path from the choroid plexus to the subventricular zone: go with the flow! Frontiers in Cellular Neuroscience. 6: 34. PMID 22907990 DOI: 10.3389/Fncel.2012.00034  0.35
2012 Oliveira AL, Sousa EC, Silva NA, Sousa N, Salgado AJ, Reis RL. Peripheral mineralization of a 3D biodegradable tubular construct as a way to enhance guidance stabilization in spinal cord injury regeneration. Journal of Materials Science. Materials in Medicine. 23: 2821-30. PMID 22903600 DOI: 10.1007/S10856-012-4741-0  0.715
2012 Falcão AM, Palha JA, Ferreira AC, Marques F, Sousa N, Sousa JC. Topographical analysis of the subependymal zone neurogenic niche. Plos One. 7: e38647. PMID 22745673 DOI: 10.1371/Journal.Pone.0038647  0.352
2012 Silva NA, Cooke MJ, Tam RY, Sousa N, Salgado AJ, Reis RL, Shoichet MS. The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fate Biomaterials. 33: 6345-6354. PMID 22698724 DOI: 10.1016/J.Biomaterials.2012.05.050  0.724
2012 Ribeiro CA, Fraga JS, Grãos M, Neves NM, Reis RL, Gimble JM, Sousa N, Salgado AJ. The secretome of stem cells isolated from the adipose tissue and Wharton jelly acts differently on central nervous system derived cell populations. Stem Cell Research & Therapy. 3: 18. PMID 22551705 DOI: 10.1186/Scrt109  0.627
2012 Silva-Correia J, Miranda-Gonçalves V, Salgado AJ, Sousa N, Oliveira JM, Reis RM, Reis RL. Angiogenic potential of gellan-gum-based hydrogels for application in nucleus pulposus regeneration: in vivo study. Tissue Engineering. Part A. 18: 1203-12. PMID 22439824 DOI: 10.1089/Ten.Tea.2011.0632  0.594
2012 Pinto L, Mateus-Pinheiro A, Morais M, Bessa JM, Sousa N. Immuno-Golgi as a tool for analyzing neuronal 3D-dendritic structure in phenotypically characterized neurons. Plos One. 7: e33114. PMID 22427964 DOI: 10.1371/Journal.Pone.0033114  0.609
2012 Cerqueira SR, Silva BL, Oliveira JM, Mano JF, Sousa N, Salgado AJ, Reis RL. Multifunctionalized CMCht/PAMAM dendrimer nanoparticles modulate the cellular uptake by astrocytes and oligodendrocytes in primary cultures of glial cells. Macromolecular Bioscience. 12: 591-7. PMID 22411735 DOI: 10.1002/Mabi.201100294  0.778
2012 Silva NA, Sousa RA, Pires AO, Sousa N, Salgado AJ, Reis RL. Interactions between Schwann and olfactory ensheathing cells with a starch/polycaprolactone scaffold aimed at spinal cord injury repair. Journal of Biomedical Materials Research. Part A. 100: 470-6. PMID 22125000 DOI: 10.1002/Jbm.A.33289  0.723
2012 Rodrigues AJ, Leão P, Pêgo JM, Cardona D, Carvalho MM, Oliveira M, Costa BM, Carvalho AF, Morgado P, Araújo D, Palha JA, Almeida OF, Sousa N. Mechanisms of initiation and reversal of drug-seeking behavior induced by prenatal exposure to glucocorticoids. Molecular Psychiatry. 17: 1295-305. PMID 21968930 DOI: 10.1038/Mp.2011.126  0.664
2011 Mateus-Pinheiro A, Pinto L, Sousa N. Epigenetic (de)regulation of adult hippocampal neurogenesis: implications for depression. Clinical Epigenetics. 3: 5. PMID 22414227 DOI: 10.1186/1868-7083-3-5  0.617
2011 Yu S, Yang S, Holsboer F, Sousa N, Almeida OF. Glucocorticoid regulation of astrocytic fate and function. Plos One. 6: e22419. PMID 21811605 DOI: 10.1371/Journal.Pone.0022419  0.33
2011 Ribeiro CA, Salgado AJ, Fraga JS, Silva NA, Reis RL, Sousa N. The secretome of bone marrow mesenchymal stem cells-conditioned media varies with time and drives a distinct effect on mature neurons and glial cells (primary cultures). Journal of Tissue Engineering and Regenerative Medicine. 5: 668-72. PMID 21774090 DOI: 10.1002/Term.365  0.72
2011 Pereira DR, Silva-Correia J, Caridade SG, Oliveira JT, Sousa RA, Salgado AJ, Oliveira JM, Mano JF, Sousa N, Reis RL. Development of gellan gum-based microparticles/hydrogel matrices for application in the intervertebral disc regeneration. Tissue Engineering. Part C, Methods. 17: 961-72. PMID 21574937 DOI: 10.1089/Ten.Tec.2011.0115  0.6
2011 Carvalho MM, Teixeira FG, Reis RL, Sousa N, Salgado AJ. Mesenchymal stem cells in the umbilical cord: phenotypic characterization, secretome and applications in central nervous system regenerative medicine. Current Stem Cell Research & Therapy. 6: 221-8. PMID 21476975 DOI: 10.2174/157488811796575332  0.759
2011 Marques F, Sousa JC, Coppola G, Gao F, Puga R, Brentani H, Geschwind DH, Sousa N, Correia-Neves M, Palha JA. Transcriptome signature of the adult mouse choroid plexus. Fluids and Barriers of the Cns. 8: 10. PMID 21349147 DOI: 10.1186/2045-8118-8-10  0.313
2011 Rodrigues AJ, Leão P, Carvalho M, Almeida OF, Sousa N. Potential programming of dopaminergic circuits by early life stress. Psychopharmacology. 214: 107-20. PMID 21088961 DOI: 10.1007/S00213-010-2085-3  0.653
2011 Pereira VH, Salgado AJ, Oliveira JM, Cerqueira SR, Frias AM, Fraga JS, Roque S, Falcão AM, Marques F, Neves NM, Mano JF, Reis RL, Sousa N. In vivo biodistribution of carboxymethylchitosan/poly(amidoamine) dendrimer nanoparticles in rats Journal of Bioactive and Compatible Polymers. 26: 619-627. DOI: 10.1177/0883911511425567  0.77
2010 Salgado AJ, Oliveira JM, Pirraco RP, Pereira VH, Fraga JS, Marques AP, Neves NM, Mano JF, Reis RL, Sousa N. Carboxymethylchitosan/poly(amidoamine) dendrimer nanoparticles in central nervous systems-regenerative medicine: effects on neuron/glial cell viability and internalization efficiency. Macromolecular Bioscience. 10: 1130-40. PMID 20602413 DOI: 10.1002/Mabi.201000005  0.597
2010 Yu S, Patchev AV, Wu Y, Lu J, Holsboer F, Zhang JZ, Sousa N, Almeida OF. Depletion of the neural precursor cell pool by glucocorticoids. Annals of Neurology. 67: 21-30. PMID 20186952 DOI: 10.1002/Ana.21812  0.35
2010 Salgado AJ, Reis RL, Sousa NJ, Gimble JM. Adipose tissue derived stem cells secretome: soluble factors and their roles in regenerative medicine. Current Stem Cell Research & Therapy. 5: 103-10. PMID 19941460  0.57
2010 Salgado AJ, Fraga JS, Mesquita AR, Neves NM, Reis RL, Sousa N. Role of human umbilical cord mesenchymal progenitors conditioned media in neuronal/glial cell densities, viability, and proliferation. Stem Cells and Development. 19: 1067-74. PMID 19705968 DOI: 10.1089/Scd.2009.0279  0.642
2010 Silva NA, Salgado AJ, Sousa RA, Oliveira JT, Pedro AJ, Leite-Almeida H, Cerqueira R, Almeida A, Mastronardi F, Mano JF, Neves NM, Sousa N, Reis RL. Development and characterization of a novel hybrid tissue engineering-based scaffold for spinal cord injury repair. Tissue Engineering. Part A. 16: 45-54. PMID 19614546 DOI: 10.1089/Ten.Tea.2008.0559  0.724
2010 Oliveira JM, Salgado AJ, Sousa N, Mano JF, Reis RL. Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies - A review Progress in Polymer Science (Oxford). 35: 1163-1194. DOI: 10.1016/J.Progpolymsci.2010.04.006  0.587
2009 Bessa JM, Ferreira D, Melo I, Marques F, Cerqueira JJ, Palha JA, Almeida OF, Sousa N. The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling. Molecular Psychiatry. 14: 764-73, 739. PMID 18982002 DOI: 10.1038/Mp.2008.119  0.325
2009 Salgado AJ, Sousa RA, Fraga JS, Pego JM, Silva BA, Malva JO, Neves NM, Reis RL, Sousa N. Effects of Starch/ Polycaprolactone-based Blends for Spinal Cord Injury Regeneration in Neurons/Glial Cells Viability and Proliferation Journal of Bioactive and Compatible Polymers. 24: 235-248. DOI: 10.1177/0883911509104081  0.648
2008 Gonçalves L, Silva R, Pinto-Ribeiro F, Pêgo JM, Bessa JM, Pertovaara A, Sousa N, Almeida A. Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala of the rat. Experimental Neurology. 213: 48-56. PMID 18599044 DOI: 10.1016/J.Expneurol.2008.04.043  0.318
2008 Silva R, Mesquita AR, Bessa J, Sousa JC, Sotiropoulos I, Leão P, Almeida OF, Sousa N. Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta. Neuroscience. 152: 656-69. PMID 18291594 DOI: 10.1016/J.Neuroscience.2007.12.026  0.332
2008 Cerqueira JJ, Almeida OF, Sousa N. The stressed prefrontal cortex. Left? Right! Brain, Behavior, and Immunity. 22: 630-8. PMID 18281193 DOI: 10.1016/J.Bbi.2008.01.005  0.304
2008 Sousa N, Cerqueira JJ, Almeida OF. Corticosteroid receptors and neuroplasticity. Brain Research Reviews. 57: 561-70. PMID 17692926 DOI: 10.1016/J.Brainresrev.2007.06.007  0.334
2008 Salgado AJ, Sousa N, Silva NA, Neves NM, Reis RL. Hydrogels for spinal cord injury regeneration Natural-Based Polymers For Biomedical Applications. 570-594. DOI: 10.1533/9781845694814.4.570  0.637
2007 Cerqueira JJ, Mailliet F, Almeida OF, Jay TM, Sousa N. The prefrontal cortex as a key target of the maladaptive response to stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2781-7. PMID 17360899 DOI: 10.1523/Jneurosci.4372-06.2007  0.302
2007 Leão P, Sousa JC, Oliveira M, Silva R, Almeida OF, Sousa N. Programming effects of antenatal dexamethasone in the developing mesolimbic pathways. Synapse (New York, N.Y.). 61: 40-9. PMID 17068773 DOI: 10.1002/Syn.20341  0.342
2006 Mesquita AR, Tavares HB, Silva R, Sousa N. Febrile convulsions in developing rats induce a hyperanxious phenotype later in life. Epilepsy & Behavior : E&B. 9: 401-6. PMID 16950656 DOI: 10.1016/J.Yebeh.2006.07.012  0.313
2006 Silva R, Lu J, Wu Y, Martins L, Almeida OF, Sousa N. Mapping cellular gains and losses in the postnatal dentate gyrus: implications for psychiatric disorders. Experimental Neurology. 200: 321-31. PMID 16624303 DOI: 10.1016/J.Expneurol.2006.02.119  0.325
2005 Lu J, Wu Y, Sousa N, Almeida OF. SMAD pathway mediation of BDNF and TGF beta 2 regulation of proliferation and differentiation of hippocampal granule neurons. Development (Cambridge, England). 132: 3231-42. PMID 15958511 DOI: 10.1242/Dev.01893  0.322
2005 Lu J, Némethy Z, Pego JM, Cerqueira JJ, Sousa N, Almeida OFX. Cellular and molecular analysis of stress-induced neurodegeneration – methodological considerations Techniques in the Behavioral and Neural Sciences. 15: 729-749. DOI: 10.1016/S0921-0709(05)80039-2  0.321
2002 Sousa N, Almeida OF. Corticosteroids: sculptors of the hippocampal formation. Reviews in the Neurosciences. 13: 59-84. PMID 12013026 DOI: 10.1515/Revneuro.2002.13.1.59  0.334
2000 Sousa N, Lukoyanov NV, Madeira MD, Almeida OF, Paula-Barbosa MM. Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement. Neuroscience. 97: 253-66. PMID 10799757 DOI: 10.1016/S0306-4522(00)00050-6  0.302
1998 Sousa N, Madeira MD, Paula-Barbosa MM. Effects of corticosterone treatment and rehabilitation on the hippocampal formation of neonatal and adult rats. An unbiased stereological study. Brain Research. 794: 199-210. PMID 9622630 DOI: 10.1016/S0006-8993(98)00218-2  0.302
1997 Sousa N, Madeira MD, Paula-Barbosa MM. Structural alterations of the hippocampal formation of adrenalectomized rats: an unbiased stereological study. Journal of Neurocytology. 26: 423-38. PMID 9278871 DOI: 10.1023/A:1018573105987  0.326
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