Year |
Citation |
Score |
2014 |
Ye R, Carneiro AM, Han Q, Airey D, Sanders-Bush E, Zhang B, Lu L, Williams R, Blakely RD. Quantitative trait loci mapping and gene network analysis implicate protocadherin-15 as a determinant of brain serotonin transporter expression. Genes, Brain, and Behavior. 13: 261-75. PMID 24405699 DOI: 10.1111/Gbb.12119 |
0.757 |
|
2014 |
Ye R, Carneiro AM, Airey D, Sanders-Bush E, Williams RW, Lu L, Wang J, Zhang B, Blakely RD. Evaluation of heritable determinants of blood and brain serotonin homeostasis using recombinant inbred mice. Genes, Brain, and Behavior. 13: 247-60. PMID 24102824 DOI: 10.1111/Gbb.12092 |
0.768 |
|
2012 |
Veenstra-VanderWeele J, Muller CL, Iwamoto H, Sauer JE, Owens WA, Shah CR, Cohen J, Mannangatti P, Jessen T, Thompson BJ, Ye R, Kerr TM, Carneiro AM, Crawley JN, Sanders-Bush E, et al. Autism gene variant causes hyperserotonemia, serotonin receptor hypersensitivity, social impairment and repetitive behavior. Proceedings of the National Academy of Sciences of the United States of America. 109: 5469-74. PMID 22431635 DOI: 10.1073/Pnas.1112345109 |
0.51 |
|
2012 |
Sanders-Bush E, Nichols CD. Serotonin Receptors and Neurotransmission Primer On the Autonomic Nervous System. 83-86. DOI: 10.1016/B978-0-12-386525-0.00017-2 |
0.624 |
|
2010 |
Olaghere da Silva UB, Morabito MV, Canal CE, Airey DC, Emeson RB, Sanders-Bush E. Impact of RNA editing on functions of the serotonin 2C receptor in vivo. Frontiers in Neuroscience. 4: 26. PMID 20582266 DOI: 10.3389/Neuro.23.001.2010 |
0.831 |
|
2010 |
Canal CE, Olaghere da Silva UB, Gresch PJ, Watt EE, Sanders-Bush E, Airey DC. The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen. Psychopharmacology. 209: 163-74. PMID 20165943 DOI: 10.1007/s00213-010-1784-0 |
0.816 |
|
2009 |
Lanfranco MF, Seitz PK, Morabito MV, Emeson RB, Sanders-Bush E, Cunningham KA. An innovative real-time PCR method to measure changes in RNA editing of the serotonin 2C receptor (5-HT(2C)R) in brain. Journal of Neuroscience Methods. 179: 247-57. PMID 19428534 DOI: 10.1016/J.Jneumeth.2009.01.027 |
0.518 |
|
2009 |
Canal CE, Mahautmr KC, Cao C, Sanders-Bush E, Airey DC. RNA editing of the serotonin 2C receptor and expression of Galpha(q) protein: genetic mouse models do not support a role for regulation or compensation. Journal of Neurochemistry. 108: 1136-42. PMID 19154337 DOI: 10.1111/j.1471-4159.2008.05852.x |
0.77 |
|
2009 |
Shelton RC, Sanders-Bush E, Manier DH, Lewis DA. Elevated 5-HT 2A receptors in postmortem prefrontal cortex in major depression is associated with reduced activity of protein kinase A. Neuroscience. 158: 1406-15. PMID 19111907 DOI: 10.1016/J.Neuroscience.2008.11.036 |
0.541 |
|
2008 |
Sanders-Bush E, Airey DC. Centennial perspective: serotonin receptors. Molecular Interventions. 8: 200-3. PMID 19015382 DOI: 10.1124/mi.8.5.1 |
0.765 |
|
2008 |
Hahn MK, Blackford JU, Haman K, Mazei-Robison M, English BA, Prasad HC, Steele A, Hazelwood L, Fentress HM, Myers R, Blakely RD, Sanders-Bush E, Shelton R. Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression. Genes, Brain, and Behavior. 7: 487-95. PMID 18081710 DOI: 10.1111/J.1601-183X.2007.00384.X |
0.736 |
|
2008 |
Benneyworth MA, Smith RL, Sanders-Bush E. Chronic phenethylamine hallucinogen treatment alters behavioral sensitivity to a metabotropic glutamate 2/3 receptor agonist. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2206-16. PMID 17957214 DOI: 10.1038/sj.npp.1301600 |
0.778 |
|
2007 |
Benneyworth MA, Xiang Z, Smith RL, Garcia EE, Conn PJ, Sanders-Bush E. A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. Molecular Pharmacology. 72: 477-84. PMID 17526600 DOI: 10.1124/Mol.107.035170 |
0.824 |
|
2007 |
Garcia EE, Smith RL, Sanders-Bush E. Role of G(q) protein in behavioral effects of the hallucinogenic drug 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane. Neuropharmacology. 52: 1671-7. PMID 17493641 DOI: 10.1016/J.Neuropharm.2007.03.013 |
0.712 |
|
2007 |
Hackler EA, Turner GH, Gresch PJ, Sengupta S, Deutch AY, Avison MJ, Gore JC, Sanders-Bush E. 5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation. The Journal of Pharmacology and Experimental Therapeutics. 320: 1023-9. PMID 17138863 DOI: 10.1124/Jpet.106.113357 |
0.803 |
|
2007 |
Gresch PJ, Barrett RJ, Sanders-Bush E, Smith RL. 5-Hydroxytryptamine (serotonin)2A receptors in rat anterior cingulate cortex mediate the discriminative stimulus properties of d-lysergic acid diethylamide. The Journal of Pharmacology and Experimental Therapeutics. 320: 662-9. PMID 17077317 DOI: 10.1124/jpet.106.112946 |
0.764 |
|
2007 |
Myers RL, Airey DC, Manier DH, Shelton RC, Sanders-Bush E. Polymorphisms in the regulatory region of the human serotonin 5-HT2A receptor gene (HTR2A) influence gene expression. Biological Psychiatry. 61: 167-73. PMID 16697352 DOI: 10.1016/J.Biopsych.2005.12.018 |
0.767 |
|
2006 |
Tomlinson ID, Gies AP, Gresch PJ, Dillard J, Orndorff RL, Sanders-Bush E, Hercules DM, Rosenthal SJ. Universal polyethylene glycol linkers for attaching receptor ligands to quantum dots. Bioorganic & Medicinal Chemistry Letters. 16: 6262-6. PMID 17000112 DOI: 10.1016/J.Bmcl.2006.09.031 |
0.746 |
|
2006 |
Hackler EA, Airey DC, Shannon CC, Sodhi MS, Sanders-Bush E. 5-HT(2C) receptor RNA editing in the amygdala of C57BL/6J, DBA/2J, and BALB/cJ mice. Neuroscience Research. 55: 96-104. PMID 16580757 DOI: 10.1016/J.Neures.2006.02.005 |
0.801 |
|
2005 |
Bentzen EL, Tomlinson ID, Mason J, Gresch P, Warnement MR, Wright D, Sanders-Bush E, Blakely R, Rosenthal SJ. Surface modification to reduce nonspecific binding of quantum dots in live cell assays. Bioconjugate Chemistry. 16: 1488-94. PMID 16287246 DOI: 10.1021/Bc0502006 |
0.675 |
|
2005 |
Sodhi MS, Airey DC, Lambert W, Burnet PW, Harrison PJ, Sanders-Bush E. A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts. Molecular Pharmacology. 68: 711-9. PMID 15917433 DOI: 10.1124/Mol.105.014134 |
0.769 |
|
2005 |
Fentress HM, Grinde E, Mazurkiewicz JE, Backstrom JR, Herrick-Davis K, Sanders-Bush E. Pharmacological properties of the Cys23Ser single nucleotide polymorphism in human 5-HT2C receptor isoforms. The Pharmacogenomics Journal. 5: 244-54. PMID 15912142 DOI: 10.1038/Sj.Tpj.6500315 |
0.822 |
|
2005 |
Gresch PJ, Smith RL, Barrett RJ, Sanders-Bush E. Behavioral tolerance to lysergic acid diethylamide is associated with reduced serotonin-2A receptor signaling in rat cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1693-702. PMID 15756304 DOI: 10.1038/sj.npp.1300711 |
0.755 |
|
2005 |
Benneyworth MA, Smith RL, Barrett RJ, Sanders-Bush E. Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice. Psychopharmacology. 179: 854-62. PMID 15645221 DOI: 10.1007/s00213-004-2108-z |
0.789 |
|
2005 |
Akin D, Manier DH, Sanders-Bush E, Shelton RC. Signal transduction abnormalities in melancholic depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 8: 5-16. PMID 15500705 DOI: 10.1017/S146114570400478X |
0.309 |
|
2004 |
Hazelwood LA, Sanders-Bush E. His452Tyr polymorphism in the human 5-HT2A receptor destabilizes the signaling conformation. Molecular Pharmacology. 66: 1293-300. PMID 15496511 DOI: 10.1124/mol.66.5. |
0.804 |
|
2004 |
Nichols CD, Sanders-Bush E. Molecular genetic responses to lysergic acid diethylamide include transcriptional activation of MAP kinase phosphatase-1, C/EBP-beta and ILAD-1, a novel gene with homology to arrestins. Journal of Neurochemistry. 90: 576-84. PMID 15255935 DOI: 10.1111/j.1471-4159.2004.02515.x |
0.48 |
|
2004 |
Akin D, Manier DH, Sanders-Bush E, Shelton RC. Decreased serotonin 5-HT2A receptor-stimulated phosphoinositide signaling in fibroblasts from melancholic depressed patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2081-7. PMID 15187984 DOI: 10.1038/sj.npp.1300505 |
0.565 |
|
2004 |
Sodhi MS, Sanders-Bush E. Serotonin and brain development. International Review of Neurobiology. 59: 111-74. PMID 15006487 DOI: 10.1016/S0074-7742(04)59006-2 |
0.588 |
|
2004 |
McGrew L, Price RD, Hackler E, Chang MS, Sanders-Bush E. RNA editing of the human serotonin 5-HT2C receptor disrupts transactivation of the small G-protein RhoA. Molecular Pharmacology. 65: 252-6. PMID 14722258 DOI: 10.1124/Mol.65.1.252 |
0.779 |
|
2003 |
Sanders-Bush E, Fentress H, Hazelwood L. Serotonin 5-ht2 receptors: molecular and genomic diversity. Molecular Interventions. 3: 319-30. PMID 14993464 DOI: 10.1124/Mi.3.6.319 |
0.818 |
|
2003 |
Parker LL, Backstrom JR, Sanders-Bush E, Shieh BH. Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1. The Journal of Biological Chemistry. 278: 21576-83. PMID 12682077 DOI: 10.1074/jbc.M210973200 |
0.445 |
|
2003 |
Nichols CD, Garcia EE, Sanders-Bush E. Dynamic changes in prefrontal cortex gene expression following lysergic acid diethylamide administration. Brain Research. Molecular Brain Research. 111: 182-8. PMID 12654518 DOI: 10.1016/S0169-328X(03)00029-9 |
0.756 |
|
2003 |
Miner LA, Backstrom JR, Sanders-Bush E, Sesack SR. Ultrastructural localization of serotonin2A receptors in the middle layers of the rat prelimbic prefrontal cortex. Neuroscience. 116: 107-17. PMID 12535944 DOI: 10.1016/S0306-4522(02)00580-8 |
0.424 |
|
2003 |
Smith RL, Barrett RJ, Sanders-Bush E. Discriminative stimulus properties of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane [(+/-)DOI] in C57BL/6J mice. Psychopharmacology. 166: 61-8. PMID 12474110 DOI: 10.1007/s00213-002-1252-6 |
0.455 |
|
2002 |
McGrew L, Chang MS, Sanders-Bush E. Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits. Molecular Pharmacology. 62: 1339-43. PMID 12435801 DOI: 10.1124/mol.62.6.1339 |
0.827 |
|
2002 |
Nichols CD, Ronesi J, Pratt W, Sanders-Bush E. Hallucinogens and Drosophila: linking serotonin receptor activation to behavior. Neuroscience. 115: 979-84. PMID 12435434 DOI: 10.1016/S0306-4522(02)00354-8 |
0.596 |
|
2002 |
Gresch PJ, Strickland LV, Sanders-Bush E. Lysergic acid diethylamide-induced Fos expression in rat brain: role of serotonin-2A receptors. Neuroscience. 114: 707-13. PMID 12220572 DOI: 10.1016/S0306-4522(02)00349-4 |
0.79 |
|
2002 |
Nichols CD, Sanders-Bush E. A single dose of lysergic acid diethylamide influences gene expression patterns within the mammalian brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 634-42. PMID 11927188 DOI: 10.1016/S0893-133X(01)00405-5 |
0.533 |
|
2002 |
Smith RL, Gresch PJ, Barrett RJ, Sanders-Bush E. Stimulus generalization by fenfluramine in a quipazine-ketanserin drug discrimination is not dependent on indirect serotonin release. Pharmacology, Biochemistry, and Behavior. 72: 77-85. PMID 11900772 DOI: 10.1016/S0091-3057(01)00723-7 |
0.798 |
|
2001 |
Peavy RD, Chang MS, Sanders-Bush E, Conn PJ. Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9619-28. PMID 11739572 DOI: 10.1523/Jneurosci.21-24-09619.2001 |
0.783 |
|
2001 |
Price RD, Weiner DM, Chang MS, Sanders-Bush E. RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein. The Journal of Biological Chemistry. 276: 44663-8. PMID 11572865 DOI: 10.1074/jbc.M106745200 |
0.787 |
|
2001 |
Berg KA, Cropper JD, Niswender CM, Sanders-Bush E, Emeson RB, Clarke WP. RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity. British Journal of Pharmacology. 134: 386-92. PMID 11564657 DOI: 10.1038/Sj.Bjp.0704255 |
0.598 |
|
2001 |
Niswender CM, Herrick-Davis K, Dilley GE, Meltzer HY, Overholser JC, Stockmeier CA, Emeson RB, Sanders-Bush E. RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 478-91. PMID 11282248 DOI: 10.1016/S0893-133X(00)00223-2 |
0.493 |
|
2001 |
Bubser M, Backstrom JR, Sanders-Bush E, Roth BL, Deutch AY. Distribution of serotonin 5-HT(2A) receptors in afferents of the rat striatum. Synapse (New York, N.Y.). 39: 297-304. PMID 11169779 DOI: 10.1002/1098-2396(20010315)39:4<297::Aid-Syn1012>3.0.Co;2-Q |
0.497 |
|
2000 |
Chang MS, Tam JP, Sanders-Bush E. Dissecting intracellular signaling pathways with membrane-permeable peptides. Science's Stke : Signal Transduction Knowledge Environment. 2000: pl1. PMID 11752605 DOI: 10.1126/stke.2000.47.pl1 |
0.526 |
|
2000 |
Price RD, Sanders-Bush E. RNA editing of the human serotonin 5-HT(2C) receptor delays agonist-stimulated calcium release. Molecular Pharmacology. 58: 859-62. PMID 10999958 DOI: 10.1124/Mol.58.4.859 |
0.692 |
|
2000 |
Backstrom JR, Price RD, Reasoner DT, Sanders-Bush E. Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses. The Journal of Biological Chemistry. 275: 23620-6. PMID 10816555 DOI: 10.1074/Jbc.M000922200 |
0.725 |
|
2000 |
Chang M, Zhang L, Tam JP, Sanders-Bush E. Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells. The Journal of Biological Chemistry. 275: 7021-9. PMID 10702266 DOI: 10.1074/jbc.275.10.7021 |
0.713 |
|
1999 |
Smith RL, Barrett RJ, Sanders-Bush E. Mechanism of tolerance development to 2,5-dimethoxy-4-iodoamphetamine in rats: down-regulation of the 5-HT2A, but not 5-HT2C, receptor. Psychopharmacology. 144: 248-54. PMID 10435391 DOI: 10.1007/s002130051000 |
0.377 |
|
1999 |
Backstrom JR, Chang MS, Chu H, Niswender CM, Sanders-Bush E. Agonist-directed signaling of serotonin 5-HT2C receptors: differences between serotonin and lysergic acid diethylamide (LSD). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 77S-81S. PMID 10432492 DOI: 10.1016/S0893-133X(99)00005-6 |
0.723 |
|
1999 |
Bancila M, Vergé D, Rampin O, Backstrom JR, Sanders-Bush E, McKenna KE, Marson L, Calas A, Giuliano F. 5-Hydroxytryptamine2C receptors on spinal neurons controlling penile erection in the rat. Neuroscience. 92: 1523-37. PMID 10426504 DOI: 10.1016/S0306-4522(99)00082-2 |
0.356 |
|
1999 |
Willins DL, Berry SA, Alsayegh L, Backstrom JR, Sanders-Bush E, Friedman L, Roth BL. Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo. Neuroscience. 91: 599-606. PMID 10366017 DOI: 10.1016/S0306-4522(98)00653-8 |
0.419 |
|
1999 |
Niswender CM, Copeland SC, Herrick-Davis K, Emeson RB, Sanders-Bush E. RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity. The Journal of Biological Chemistry. 274: 9472-8. PMID 10092629 DOI: 10.1074/Jbc.274.14.9472 |
0.418 |
|
1999 |
Grotewiel MS, Sanders-Bush E. Differences in agonist-independent activity of 5-Ht2A and 5-HT2c receptors revealed by heterologous expression. Naunyn-Schmiedeberg's Archives of Pharmacology. 359: 21-7. PMID 9933146 DOI: 10.1007/Pl00005318 |
0.511 |
|
1998 |
Willins DL, Alsayegh L, Berry SA, Backstrom JR, Sanders-Bush E, Friedman L, Khan N, Roth BL. Serotonergic antagonist effects on trafficking of serotonin 5-HT2A receptors in vitro and in vivo. Annals of the New York Academy of Sciences. 861: 121-7. PMID 9928248 DOI: 10.1111/J.1749-6632.1998.Tb10182.X |
0.485 |
|
1998 |
Niswender CM, Sanders-Bush E, Emeson RB. Identification and characterization of RNA editing events within the 5-HT2C receptor. Annals of the New York Academy of Sciences. 861: 38-48. PMID 9928237 DOI: 10.1111/J.1749-6632.1998.Tb10171.X |
0.343 |
|
1998 |
Smith RL, Canton H, Barrett RJ, Sanders-Bush E. Agonist properties of N,N-dimethyltryptamine at serotonin 5-HT2A and 5-HT2C receptors. Pharmacology, Biochemistry, and Behavior. 61: 323-30. PMID 9768567 DOI: 10.1016/S0091-3057(98)00110-5 |
0.502 |
|
1997 |
Monte AP, Waldman SR, Marona-Lewicka D, Wainscott DB, Nelson DL, Sanders-Bush E, Nichols DE. Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives. Journal of Medicinal Chemistry. 40: 2997-3008. PMID 9301661 DOI: 10.1021/jm970219x |
0.367 |
|
1997 |
Burns CM, Chu H, Rueter SM, Hutchinson LK, Canton H, Sanders-Bush E, Emeson RB. Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature. 387: 303-8. PMID 9153397 DOI: 10.1038/387303A0 |
0.588 |
|
1997 |
Gether U, Ballesteros JA, Seifert R, Sanders-Bush E, Weinstein H, Kobilka BK. Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility. The Journal of Biological Chemistry. 272: 2587-90. PMID 9006889 DOI: 10.1074/jbc.272.5.2587 |
0.305 |
|
1996 |
Canton H, Emeson RB, Barker EL, Backstrom JR, Lu JT, Chang MS, Sanders-Bush E. Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing. Molecular Pharmacology. 50: 799-807. PMID 8863824 |
0.616 |
|
1996 |
Westphal RS, Sanders-Bush E. Differences in agonist-independent and -dependent 5-hydroxytryptamine2C receptor-mediated cell division. Molecular Pharmacology. 49: 474-80. PMID 8643087 |
0.376 |
|
1995 |
Onaivi ES, Bishop-Robinson C, Darmani NA, Sanders-Bush E. Behavioral effects of (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, (DOI) in the elevated plus-maze test. Life Sciences. 57: 2455-66. PMID 8847967 DOI: 10.1016/0024-3205(95)02242-9 |
0.437 |
|
1995 |
Backstrom JR, Westphal RS, Canton H, Sanders-Bush E. Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides. Brain Research. Molecular Brain Research. 33: 311-8. PMID 8750891 DOI: 10.1016/0169-328X(95)00156-M |
0.406 |
|
1995 |
Westphal RS, Backstrom JR, Sanders-Bush E. Increased basal phosphorylation of the constitutively active serotonin 2C receptor accompanies agonist-mediated desensitization. Molecular Pharmacology. 48: 200-5. PMID 7651352 |
0.433 |
|
1995 |
Ike J, Canton H, Sanders-Bush E. Developmental switch in the hippocampal serotonin receptor linked to phosphoinositide hydrolysis. Brain Research. 678: 49-54. PMID 7620898 DOI: 10.1016/0006-8993(95)00143-E |
0.552 |
|
1995 |
Smith RL, Barrett RJ, Sanders-Bush E. Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor. The Journal of Pharmacology and Experimental Therapeutics. 275: 1050-7. PMID 7473132 |
0.464 |
|
1994 |
Sanders-Bush E. Neurochemical evidence that hallucinogenic drugs are 5-HT1c receptor agonists: what next? Nida Research Monograph. 146: 203-13. PMID 8742800 |
0.32 |
|
1994 |
Mayer SE, Sanders-Bush E. 5-Hydroxytryptamine type 2A and 2C receptors linked to Na+/K+/Cl- cotransport. Molecular Pharmacology. 45: 991-6. PMID 8190114 |
0.343 |
|
1994 |
Westphal RS, Sanders-Bush E. Reciprocal binding properties of 5-hydroxytryptamine type 2C receptor agonists and inverse agonists. Molecular Pharmacology. 46: 937-42. PMID 7969083 |
0.401 |
|
1994 |
Grotewiel MS, Chu H, Sanders-Bush E. m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine are partial agonists at cloned 5-HT2A receptors expressed in fibroblasts. The Journal of Pharmacology and Experimental Therapeutics. 271: 1122-6. PMID 7965773 |
0.421 |
|
1994 |
Grotewiel MS, Sanders-Bush E. Regulation of serotonin2A receptors in heterologous expression systems. Journal of Neurochemistry. 63: 1255-60. PMID 7931277 |
0.345 |
|
1994 |
Barker EL, Westphal RS, Schmidt D, Sanders-Bush E. Constitutively active 5-hydroxytryptamine2C receptors reveal novel inverse agonist activity of receptor ligands. The Journal of Biological Chemistry. 269: 11687-90. PMID 7909313 |
0.383 |
|
1993 |
Barker EL, Sanders-Bush E. 5-hydroxytryptamine1C receptor density and mRNA levels in choroid plexus epithelial cells after treatment with mianserin and (-)-1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane. Molecular Pharmacology. 44: 725-30. PMID 8232222 |
0.423 |
|
1992 |
Glennon RA, Teitler M, Sanders-Bush E. Hallucinogens and serotonergic mechanisms. Nida Research Monograph. 119: 131-5. PMID 1435968 |
0.422 |
|
1992 |
Burris KD, Sanders-Bush E. Unsurmountable antagonism of brain 5-hydroxytryptamine2 receptors by (+)-lysergic acid diethylamide and bromo-lysergic acid diethylamide. Molecular Pharmacology. 42: 826-30. PMID 1359397 |
0.407 |
|
1992 |
Esterle TM, Sanders-Bush E. Serotonin agonists increase transferrin levels via activation of 5-HT1C receptors in choroid plexus epithelium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4775-82. PMID 1334504 DOI: 10.1523/Jneurosci.12-12-04775.1992 |
0.572 |
|
1991 |
Burris KD, Breeding M, Sanders-Bush E. (+)Lysergic acid diethylamide, but not its nonhallucinogenic congeners, is a potent serotonin 5HT1C receptor agonist. The Journal of Pharmacology and Experimental Therapeutics. 258: 891-6. PMID 1679849 |
0.488 |
|
1991 |
Sanders-Bush E, Breeding M. Choroid plexus epithelial cells in primary culture: a model of 5HT1C receptor activation by hallucinogenic drugs. Psychopharmacology. 105: 340-6. PMID 1665919 DOI: 10.1007/BF02244428 |
0.54 |
|
1991 |
Barker EL, Burris KD, Sanders-Bush E. Phosphoinositide hydrolysis linked 5-HT2 receptors in fibroblasts from choroid plexus. Brain Research. 552: 330-2. PMID 1655172 DOI: 10.1016/0006-8993(91)90099-H |
0.535 |
|
1990 |
Sanders-Bush E, Breeding M. Serotonin1c receptor reserve in choroid plexus masks receptor subsensitivity. The Journal of Pharmacology and Experimental Therapeutics. 252: 984-8. PMID 2319481 |
0.474 |
|
1990 |
Sanders-Bush E, Tsutsumi M, Burris KD. Serotonin receptors and phosphatidylinositol turnover. Annals of the New York Academy of Sciences. 600: 224-35; discussion 2. PMID 2252311 DOI: 10.1111/J.1749-6632.1990.Tb16885.X |
0.536 |
|
1990 |
Smith RL, Barrett RJ, Sanders-Bush E. Adaptation of brain 5HT2 receptors after mianserin treatment: receptor sensitivity, not receptor binding, more accurately correlates with behavior. The Journal of Pharmacology and Experimental Therapeutics. 254: 484-8. PMID 2166792 |
0.471 |
|
1990 |
Tsutsumi M, Sanders-Bush E. 5-HT-induced transferrin production by choroid plexus epithelial cells in culture: role of 5-HT1c receptor. The Journal of Pharmacology and Experimental Therapeutics. 254: 253-7. PMID 2164094 |
0.473 |
|
1990 |
Sanders-Bush E. Adaptive regulation of central serotonin receptors linked to phosphoinositide hydrolysis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 3: 411-6. PMID 1964049 |
0.476 |
|
1990 |
Sanders-Bush E, Tsutsumi M. Role of serotonin 5HT1c receptors in the regulation of protein synthesis by choroid plexus epithelial cells in culture European Journal of Pharmacology. 183: 2352. DOI: 10.1016/0014-2999(90)93914-C |
0.301 |
|
1989 |
Sanders-Bush E, Breeding M, Knoth K, Tsutsumi M. Sertraline-induced desensitization of the serotonin 5HT-2 receptor transmembrane signaling system. Psychopharmacology. 99: 64-9. PMID 2550988 DOI: 10.1007/BF00634454 |
0.547 |
|
1988 |
Sanders-Bush E, Breeding M. Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus. The Journal of Pharmacology and Experimental Therapeutics. 247: 169-73. PMID 3139864 |
0.433 |
|
1988 |
Sanders-Bush E, Burris KD, Knoth K. Lysergic acid diethylamide and 2,5-dimethoxy-4-methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis. The Journal of Pharmacology and Experimental Therapeutics. 246: 924-8. PMID 2843634 |
0.48 |
|
1988 |
Gillespie DD, Manier DH, Sanders-Bush E, Sulser F. The serotonin/norepinephrine-link in brain. II. Role of serotonin in the regulation of beta adrenoceptors in the low agonist affinity conformation. The Journal of Pharmacology and Experimental Therapeutics. 244: 154-9. PMID 2826764 |
0.614 |
|
1987 |
Sanders-Bush E, Breeding M, Roznoski M. 5HT2 binding sites after mianserin: comparison of loss of sites and brain levels of drug. European Journal of Pharmacology. 133: 199-204. PMID 3816985 DOI: 10.1016/0014-2999(87)90151-8 |
0.409 |
|
1987 |
Conn PJ, Janowsky A, Sanders-Bush E. Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus. Brain Research. 400: 396-8. PMID 3815085 DOI: 10.1016/0006-8993(87)90641-X |
0.535 |
|
1987 |
Conn PJ, Sanders-Bush E. Relative efficacies of piperazines at the phosphoinositide hydrolysis-linked serotonergic (5-HT-2 and 5-HT-1c) receptors. The Journal of Pharmacology and Experimental Therapeutics. 242: 552-7. PMID 3039120 |
0.463 |
|
1987 |
Manier DH, Gillespie DD, Sanders-Bush E, Sulser F. The serotonin/noradrenaline-link in brain. I. The role of noradrenaline and serotonin in the regulation of density and function of beta adrenoceptors and its alteration by desipramine. Naunyn-Schmiedeberg's Archives of Pharmacology. 335: 109-14. PMID 3031514 DOI: 10.1007/Bf00177710 |
0.634 |
|
1987 |
Sulser F, Sanders-Bush E. The serotonin-norepinephrine link hypothesis of affective disorders: receptor-receptor interactions in brain. Advances in Experimental Medicine and Biology. 221: 489-502. PMID 2829588 DOI: 10.1007/978-1-4684-7618-7_35 |
0.648 |
|
1987 |
Conn PJ, Sanders-Bush E. Central serotonin receptors: effector systems, physiological roles and regulation. Psychopharmacology. 92: 267-77. PMID 2819915 DOI: 10.1007/BF00210830 |
0.522 |
|
1986 |
Blackshear MA, Martin LL, Sanders-Bush E. Adaptive changes in the 5-HT2 binding site after chronic administration of agonists and antagonists. Neuropharmacology. 25: 1267-71. PMID 3796800 DOI: 10.1016/0028-3908(86)90146-2 |
0.513 |
|
1986 |
Sanders-Bush E, Conn PJ. Effector systems coupled to serotonin receptors in brain: serotonin stimulated phosphoinositide hydrolysis. Psychopharmacology Bulletin. 22: 829-36. PMID 3025911 |
0.346 |
|
1986 |
Conn PJ, Sanders-Bush E. Regulation of serotonin-stimulated phosphoinositide hydrolysis: relation to the serotonin 5-HT-2 binding site. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 3669-75. PMID 3025382 DOI: 10.1523/Jneurosci.06-12-03669.1986 |
0.524 |
|
1986 |
Conn PJ, Sanders-Bush E. Agonist-induced phosphoinositide hydrolysis in choroid plexus. Journal of Neurochemistry. 47: 1754-60. PMID 3021903 |
0.418 |
|
1986 |
Conn PJ, Sanders-Bush E. Biochemical characterization of serotonin stimulated phosphoinositide turnover. Life Sciences. 38: 663-9. PMID 3003490 DOI: 10.1016/0024-3205(86)90060-3 |
0.497 |
|
1986 |
Conn PJ, Sanders-Bush E, Hoffman BJ, Hartig PR. A unique serotonin receptor in choroid plexus is linked to phosphatidylinositol turnover. Proceedings of the National Academy of Sciences of the United States of America. 83: 4086-8. PMID 2940597 DOI: 10.1073/Pnas.83.11.4086 |
0.504 |
|
1985 |
Sanders-Bush E, Conn J, Sulser F. The serotonin/norepinephrine-linked beta-adrenoceptor system and the mode of action of antidepressants. Psychopharmacology Bulletin. 21: 373-8. PMID 2994152 |
0.501 |
|
1985 |
Conn PJ, Sanders-Bush E. Serotonin-stimulated phosphoinositide turnover: mediation by the S2 binding site in rat cerebral cortex but not in subcortical regions. The Journal of Pharmacology and Experimental Therapeutics. 234: 195-203. PMID 2989504 |
0.377 |
|
1985 |
Conn PJ, Sanders-Bush E. Regional analysis of serotonin (5HT) stimulated phosphatidylinositol (PI) turnover in rat brain Federation Proceedings. 44: No. 8280. |
0.337 |
|
1984 |
Friedman RL, Barrett RJ, Sanders-Bush E. Discriminative stimulus properties of quipazine: mediation by serotonin2 binding sites. The Journal of Pharmacology and Experimental Therapeutics. 228: 628-35. PMID 6707913 |
0.38 |
|
1984 |
Friedman RL, Sanders-Bush E, Barrett RL. Clozapine blocks disruptive and discriminative stimulus effects of quipazine. European Journal of Pharmacology. 106: 191-3. PMID 6529966 DOI: 10.1016/0014-2999(84)90695-2 |
0.368 |
|
1984 |
Conn PJ, Sanders-Bush E. Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex. Neuropharmacology. 23: 993-6. PMID 6483122 DOI: 10.1016/0028-3908(84)90017-0 |
0.521 |
|
1983 |
Blackshear MA, Friedman RL, Sanders-Bush E. Acute and chronic effects of serotonin (5HT) antagonists on serotonin binding sites. Naunyn-Schmiedeberg's Archives of Pharmacology. 324: 125-9. PMID 6646240 DOI: 10.1007/BF00497017 |
0.323 |
|
1983 |
Friedman R, Barrett RJ, Sanders-Bush E. Additional evidence that L-5-hydroxytryptophan discrimination models a unique serotonin receptor. Psychopharmacology. 80: 209-13. PMID 6137018 DOI: 10.1007/BF00436154 |
0.471 |
|
1982 |
Martin LL, Sanders-Bush E. Comparison of the pharmacological characteristics of 5 HT1 and 5 HT2 binding sites with those of serotonin autoreceptors which modulate serotonin release. Naunyn-Schmiedeberg's Archives of Pharmacology. 321: 165-70. PMID 7155196 DOI: 10.1007/BF00505480 |
0.489 |
|
1982 |
Blackshear MA, Sanders-Bush E. Serotonin receptor sensitivity after acute and chronic treatment with mianserin. The Journal of Pharmacology and Experimental Therapeutics. 221: 303-8. PMID 7077527 |
0.351 |
|
1982 |
Martin LL, Sanders-Bush E. The serotonin autoreceptor: antagonism by quipazine. Neuropharmacology. 21: 445-50. PMID 6981071 DOI: 10.1016/0028-3908(82)90029-6 |
0.506 |
|
1982 |
Barrett RJ, Blackshear MA, Sanders-Bush E. Discriminative stimulus properties of L-5-hydroxytryptophan: behavioral evidence for multiple serotonin receptors. Psychopharmacology. 76: 29-35. PMID 6805004 DOI: 10.1007/BF00430750 |
0.498 |
|
1982 |
Blackshear MA, Sanders-Bush E. Effects of mianserin on serotonin receptor subtypes Federation Proceedings. 41: 7984. |
0.437 |
|
1982 |
Martin LL, Sanders-Bush E. Characterization of the serotonin (5HT) autoreceptor Federation Proceedings. 41: No. 6187. |
0.374 |
|
1982 |
Friedman R, Sanders-Bush E, Barrett RJ. Serotonin antagonists in models of serotonin receptor subtypes Federation Proceedings. 41: No. 6244. |
0.442 |
|
1981 |
Blackshear MA, Steranka LR, Sanders-Bush E. Multiple serotonin receptors: regional distribution and effect of Raphe lesions. European Journal of Pharmacology. 76: 325-34. PMID 7327207 DOI: 10.1016/0014-2999(81)90103-5 |
0.5 |
|
1980 |
Bush MT, Sanders-Bush E. Diazomethane: improved analytical and distillation techniques for small quantities and some synthetic applications. Analytical Biochemistry. 106: 351-62. PMID 6108732 DOI: 10.1016/0003-2697(80)90532-1 |
0.525 |
|
1979 |
Steranka LR, Sanders-Bush E. Species differences in the rate of disappearance of fenfluramine and its effects on brain serotonin neurons. Biochemical Pharmacology. 28: 3103-7. PMID 518708 DOI: 10.1016/0006-2952(79)90619-1 |
0.451 |
|
1979 |
Mobley PL, Sanders-Bush E, Smith HE, Sulser F. Modification of the noradrenergic cyclic AMP generating system in the rat limbic forebrain by amphetamine: role of its hydroxylated metabolites. Naunyn-Schmiedeberg's Archives of Pharmacology. 306: 267-73. PMID 224324 DOI: 10.1007/Bf00507113 |
0.593 |
|
1979 |
Steranka LR, Sanders-Bush E. Long-term effects of fenfluramine on central serotonergic mechanisms. Neuropharmacology. 18: 895-903. PMID 95210 DOI: 10.1016/0028-3908(79)90088-1 |
0.482 |
|
1978 |
Steranka LR, Sanders-Bush E. Long-term effects of continuous exposure to p-chloroamphetamine on central serotonergic mechanisms in mice. Biochemical Pharmacology. 27: 2033-7. PMID 718726 DOI: 10.1016/0006-2952(78)90063-1 |
0.418 |
|
1978 |
Steranka LR, Sanders-Bush E. Long-term reduction of brain serotonin by p-chloroamphetamine: effects of inducers and inhibitors of drug metabolism. The Journal of Pharmacology and Experimental Therapeutics. 206: 460-7. PMID 682126 |
0.32 |
|
1978 |
Massari VJ, Tizabi Y, Sanders-Bush E. Evaluation of the neurotoxic effects of p-chloroamphetamine: a histological and biochemical study. Neuropharmacology. 17: 541-8. PMID 80767 DOI: 10.1016/0028-3908(78)90062-X |
0.301 |
|
1978 |
Steranka LR, Sanders-Bush E. Biochemical studies of the mechanism of the depletion of brain serotonin (5HT) by fenfluramine Pharmacologist. 20: No. 164. |
0.365 |
|
1977 |
El-Yousef MK, Steranka L, Sanders-Bush E. Rapid tolerance to the motor effects of p-chloroamphetamine in rats. Psychopharmacology. 55: 109-14. PMID 414268 DOI: 10.1007/BF01457844 |
0.349 |
|
1977 |
Steranka LR, Barrett RJ, Sanders-Bush E. Facilitation of Sidman avoidance performance by p-chloroamphetamine: role of biogenic amines. Neuropharmacology. 16: 751-9. PMID 22828 DOI: 10.1016/0028-3908(77)90133-2 |
0.47 |
|
1976 |
Sanders-Bush E, Oates JA, Bush MT. Metabolism of bufotenine-2'-14C in human volunteers. Life Sciences. 19: 1407-11. PMID 994734 DOI: 10.1016/0024-3205(76)90441-0 |
0.537 |
|
1975 |
Sanders-Bush E, Bushing JA, Sulser F. Long-term effects of p-chloroamphetamine and related drugs on central serotonergic mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 192: 33-41. PMID 1123726 |
0.623 |
|
1975 |
Massari VJ, Sanders-Bush E. Synaptosomal uptake and levels of serotonin in rat brain areas after p-chloroamphetamine or B-9 lesions. European Journal of Pharmacology. 33: 419-22. PMID 1102320 DOI: 10.1016/0014-2999(75)90190-9 |
0.388 |
|
1975 |
Gallager DW, Sanders-Bush E, Aghajanian GK, Sulser F. An evaluation of the use of intraventricularly administered [3H]5-hydroxytryptamine as a marker for endogenous brain 5-hydroxytryptamine. Brain Research. 93: 111-22. PMID 1040550 DOI: 10.1016/0006-8993(75)90289-9 |
0.65 |
|
1974 |
Smith HE, Burrows EP, Miano JD, Mount CD, Sanders-Bush E, Sulser F. Action of (S)-and(R)-para-substituted amphetamine hydrochlorides and (alphaS)-and (alphaR)-p-chloronorephedrine and (alphaS)-and (alphaR)-p-chloronorpseudoephedrine hydrochlorides on the level of 5-hydroxytryptamine and the activity of tryptophan hydroxylase in rat brain. Journal of Medicinal Chemistry. 17: 416-21. PMID 4830539 DOI: 10.1021/Jm00250A010 |
0.537 |
|
1974 |
Schaefer GJ, Barrett RJ, Sanders-Bush E, Vorhees CV. p-Chloroamphetamine: evidence against a serotonin mediated learning deficit in PKU. Pharmacology, Biochemistry, and Behavior. 2: 783-9. PMID 4478023 DOI: 10.1016/0091-3057(74)90111-7 |
0.446 |
|
1974 |
Sanders-Bush E, Gallager DA, Sulser F. On the mechanism of brain 5-hydroxytryptamine depletion by p-chloroamphetamine and related drugs and the specificity of their action. Advances in Biochemical Psychopharmacology. 10: 185-94. PMID 4276953 |
0.505 |
|
1974 |
Sulser F, Sanders-Bush E. Halogen substitution of amphetamine biochemical and pharmacological consequences Biochemical Pharmacology. 23: 826-832. DOI: 10.1016/0006-2952(74)90142-7 |
0.564 |
|
1974 |
Smith HE, Burrows EP, Miano JD, Mount CD, Sanders-Bush E, Sulser F. Action of (S)- and (R)-para-substituted amphetamine hydrochlorides and (αS)- and (αR)-p-chloronorephedrine and (αS)- and (αR)-p-chloronorpseudoephedrine hydrochlorides on the level of 5-hydroxytryptamine and the activity of tryptophan hydroxylase in rat brain Journal of Medicinal Chemistry. 17: 416-421. |
0.504 |
|
1973 |
Sulser F, Sanders-Bush E. Halogen substitution of amphetamine-like drugs: Biochemical and pharmacological consequences Life Sciences. 13: clvii-clviii. DOI: 10.1016/0024-3205(73)90400-1 |
0.536 |
|
1972 |
Gallager DW, Sanders-Bush E, Sulser F. Dissociation between behavioral effects and changes in metabolism of cerebral serotonin following 9 -tetrahydrocannabinol. Psychopharmacologia. 26: 337-45. PMID 4638199 DOI: 10.1007/Bf00421899 |
0.648 |
|
1972 |
Sanders-Bush E, Bushing JA, Sulser F. Long-term effects of p-chloroamphetamine on tryptophan hydroxylase activity and on the levels of 5-hydroxytryptamine and 5-hydroxyindole acetic acid in brain. European Journal of Pharmacology. 20: 385-8. PMID 4264678 DOI: 10.1016/0014-2999(72)90204-X |
0.564 |
|
1972 |
Sanders-Bush E, Bushing JA, Sulser F. p-Chloroamphetamine--inhibition of cerebral tryptophan hydroxylase. Biochemical Pharmacology. 21: 1501-10. PMID 4260485 DOI: 10.1016/0006-2952(72)90375-9 |
0.619 |
|
1971 |
Yarbrough GG, Buxbaum DM, Sanders-Bush E. Increased serotonin turnover in the acutely morphine treated rat. Life Sciences. Pt. 1: Physiology and Pharmacology. 10: 977-83. PMID 5570138 DOI: 10.1016/0024-3205(71)90255-4 |
0.381 |
|
1971 |
Sulser F, Sanders-Bush E. Effect of drugs on amines in the CNS. Annual Review of Pharmacology. 11: 209-30. PMID 4948498 DOI: 10.1146/annurev.pa.11.040171.001233 |
0.468 |
|
1970 |
Strada SJ, Sanders-Bush E, Sulser F. p-Chloroamphetamine. Temporal relationship between psychomotor stimulation and metabolism of brain norepinephrine. Biochemical Pharmacology. 19: 2621-9. PMID 5478286 DOI: 10.1016/0006-2952(70)90012-2 |
0.613 |
|
1970 |
Sanders-Bush E, Sulser F. P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin. The Journal of Pharmacology and Experimental Therapeutics. 175: 419-26. PMID 5312363 |
0.531 |
|
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