Scheherazade Sadegh-Nasseri - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Immunology, Biochemistry, Pathology

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Welsh RA, Song N, Park CS, Peske JD, Sadegh-Nasseri S. H2-O deficiency promotes regulatory T cell differentiation and CD4 T cell hyperactivity. Frontiers in Immunology. 14: 1304798. PMID 38250071 DOI: 10.3389/fimmu.2023.1304798  0.364
2023 Guan J, Peske JD, Manoharan Valerio M, Park C, Robey EA, Sadegh-Nasseri S. Commensal bacteria maintain a Qa-1-restricted unconventional CD8 T population in gut epithelium. Elife. 12. PMID 38127067 DOI: 10.7554/eLife.90466  0.382
2023 Song N, Welsh RA, Sadegh-Nasseri S. Proper development of long-lived memory CD4 T cells requires HLA-DO function. Frontiers in Immunology. 14: 1277609. PMID 37908352 DOI: 10.3389/fimmu.2023.1277609  0.849
2023 Welsh RA, Song N, Park CS, Peske JD, Sadegh-Nasseri S. H2-O deficiency promotes regulatory T cell differentiation and CD4 T cell hyperactivity. Biorxiv : the Preprint Server For Biology. PMID 37645777 DOI: 10.1101/2023.08.14.553240  0.803
2023 Sengupta S, Zhang J, Reed MC, Yu J, Kim A, Boronina TN, Board NL, Wrabl JO, Shenderov K, Welsh RA, Yang W, Timmons AE, Hoh R, Cole RN, Deeks SG, ... ... Sadegh-Nasseri S, et al. A cell-free antigen processing system informs HIV-1 epitope selection and vaccine design. The Journal of Experimental Medicine. 220. PMID 37058141 DOI: 10.1084/jem.20221654  0.809
2023 Guan J, Valerio MM, Peske JD, Park C, Robey EA, Sadegh-Nasseri S, Shastri N. Commensal Bacteria Maintain a Qa-1 -restricted Unconventional CD8 T Population in Gut Epithelium. Biorxiv : the Preprint Server For Biology. PMID 36909616 DOI: 10.1101/2023.03.01.530600  0.635
2022 Martín-Esteban A, Rodriguez JC, Peske D, Lopez de Castro JA, Shastri N, Sadegh-Nasseri S. The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities. Frontiers in Immunology. 13: 1066483. PMID 36569828 DOI: 10.3389/fimmu.2022.1066483  0.681
2022 Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, ... ... Sadegh-Nasseri S, et al. TCR-mimic bispecific antibodies to target the HIV-1 reservoir. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123406119. PMID 35394875 DOI: 10.1073/pnas.2123406119  0.815
2021 Sadegh-Nasseri S, Springer S. Editorial overview: Nature repeating itself: conformational flexibility determines MHC class I and class II epitope selection. Current Opinion in Immunology. 70: iii-iv. PMID 34391569 DOI: 10.1016/j.coi.2021.07.008  0.419
2021 Welsh RA, Song N, Sadegh-Nasseri S. How Does B Cell Antigen Presentation Affect Memory CD4 T Cell Differentiation and Longevity? Frontiers in Immunology. 12: 677036. PMID 34177919 DOI: 10.3389/fimmu.2021.677036  0.826
2021 Sadegh-Nasseri S. Partnering for the major histocompatibility complex class II and antigenic determinant requires flexibility and chaperons. Current Opinion in Immunology. 70: 112-121. PMID 34146954 DOI: 10.1016/j.coi.2021.05.005  0.555
2020 Song N, Sengupta S, Khoruzhenko S, Welsh RA, Kim A, Kumar MR, Sønder SU, Sidhom JW, Zhang H, Jie C, Siliciano RF, Sadegh-Nasseri S. Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence. Cellular Immunology. 357: 104210. PMID 32987276 DOI: 10.1016/J.Cellimm.2020.104210  0.76
2020 Welsh RA, Sadegh-Nasseri S. The love and hate relationship of HLA-DM/DO in the selection of immunodominant epitopes. Current Opinion in Immunology. 64: 117-123. PMID 32599219 DOI: 10.1016/J.Coi.2020.05.007  0.874
2020 Welsh RA, Song N, Foss CA, Boronina T, Cole RN, Sadegh-Nasseri S. Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases. Plos Biology. 18: e3000590. PMID 32069316 DOI: 10.1371/Journal.Pbio.3000590  0.843
2019 Ahmed R, Omidian Z, Giwa A, Cornwell B, Majety N, Bell DR, Lee S, Zhang H, Michels A, Desiderio S, Sadegh-Nasseri S, Rabb H, Gritsch S, Suva ML, Cahan P, et al. A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen. Cell. 177: 1583-1599.e16. PMID 31150624 DOI: 10.1016/J.Cell.2019.05.007  0.743
2019 Kim A, Ishizuka IE, Hartman IZ, Poluektov Y, Narayan K, Sadegh-Nasseri S. Studying MHC Class II Peptide Loading and Editing In Vitro. Methods in Molecular Biology (Clifton, N.J.). 1988: 343-355. PMID 31147951 DOI: 10.1007/978-1-4939-9450-2_24  0.835
2019 Welsh R, Song N, Sadegh-Nasseri S. What to do with HLA-DO/H-2O two decades later? Immunogenetics. PMID 30683973 DOI: 10.1007/S00251-018-01097-3  0.853
2018 Sadegh-Nasseri S, Kim A. Selection of immunodominant epitopes during antigen processing is hierarchical. Molecular Immunology. PMID 30146122 DOI: 10.1016/J.Molimm.2018.08.011  0.805
2017 Kim A, Boronina TN, Cole RN, Darrah E, Sadegh-Nasseri S. Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing. Scientific Reports. 7: 46418. PMID 28422163 DOI: 10.1038/Srep46418  0.687
2016 Darrah E, Kim A, Zhang X, Boronina T, Cole RN, Fava A, Giles JT, Bingham Iii CO, Chalmers MJ, Griffin PR, Sadegh-Nasseri S, Rosen A. Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis. Journal of Proteome Research. PMID 27700100 DOI: 10.1021/Acs.Jproteome.6B00617  0.803
2016 Sadegh-Nasseri S. A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells. F1000research. 5. PMID 27347387 DOI: 10.12688/F1000Research.7664.1  0.619
2015 Sadegh-Nasseri S, Kim A. MHC Class II Auto-Antigen Presentation is Unconventional. Frontiers in Immunology. 6: 372. PMID 26257739 DOI: 10.3389/Fimmu.2015.00372  0.789
2015 Sadegh-Nasseri S, Kim A. Exogenous antigens bind MHC class II first, and are processed by cathepsins later. Molecular Immunology. 68: 81-4. PMID 26254987 DOI: 10.1016/J.Molimm.2015.07.018  0.799
2015 Kim A, Sadegh-Nasseri S. Determinants of immunodominance for CD4 T cells. Current Opinion in Immunology. 34: 9-15. PMID 25576665 DOI: 10.1016/J.Coi.2014.12.005  0.776
2014 Kim A, Hartman IZ, Poore B, Boronina T, Cole RN, Song N, Ciudad MT, Caspi RR, Jaraquemada D, Sadegh-Nasseri S. Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources. Nature Communications. 5: 5369. PMID 25413013 DOI: 10.1038/Ncomms6369  0.836
2013 Poluektov YO, Kim A, Sadegh-Nasseri S. HLA-DO and Its Role in MHC Class II Antigen Presentation. Frontiers in Immunology. 4: 260. PMID 24009612 DOI: 10.3389/Fimmu.2013.00260  0.873
2013 Poluektov YO, Kim A, Hartman IZ, Sadegh-Nasseri S. HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation. Plos One. 8: e71228. PMID 23951115 DOI: 10.1371/Journal.Pone.0071228  0.858
2013 Kim TH, Swierczewska M, Oh Y, Kim A, Jo DG, Park JH, Byun Y, Sadegh-Nasseri S, Pomper MG, Lee KC, Lee S. Mix to validate: a facile, reversible PEGylation for fast screening of potential therapeutic proteins in vivo. Angewandte Chemie (International Ed. in English). 52: 6880-4. PMID 23740787 DOI: 10.1002/Anie.201302181  0.663
2013 Kim A, Ishizuka I, Hartman I, Poluektov Y, Narayan K, Sadegh-Nasseri S. Studying MHC class II peptide loading and editing in vitro. Methods in Molecular Biology (Clifton, N.J.). 960: 447-59. PMID 23329506 DOI: 10.1007/978-1-62703-218-6_33  0.834
2013 Kim TH, Swierczewska M, Oh Y, Kim A, Jo DG, Park JH, Byun Y, Sadegh-Nasseri S, Pomper MG, Lee KC, Lee S. Rücktitelbild: Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo (Angew. Chem. 27/2013) Angewandte Chemie. 125: 7182-7182. DOI: 10.1002/Ange.201304233  0.63
2012 Sadegh-Nasseri S, Chou CL, Hartman IZ, Kim A, Narayan K. How HLA-DM works: recognition of MHC II conformational heterogeneity. Frontiers in Bioscience (Scholar Edition). 4: 1325-32. PMID 22652874 DOI: 10.2741/S334  0.873
2012 Sadegh-Nasseri S, Poluektov Y, Kim A. Understanding how HLA-DO works Molecular Immunology. 51: 29. DOI: 10.1016/J.Molimm.2012.02.080  0.801
2011 Dalai SK, Khoruzhenko S, Drake CG, Jie CC, Sadegh-Nasseri S. Resolution of infection promotes a state of dormancy and long survival of CD4 memory T cells. Immunology and Cell Biology. 89: 870-81. PMID 21358746 DOI: 10.1038/Icb.2011.2  0.815
2010 Hartman IZ, Kim A, Cotter RJ, Walter K, Dalai SK, Boronina T, Griffith W, Lanar DE, Schwenk R, Krzych U, Cole RN, Sadegh-Nasseri S. A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes. Nature Medicine. 16: 1333-40. PMID 21037588 DOI: 10.1038/Nm.2248  0.85
2010 Sadegh-Nasseri S, Natarajan S, Chou CL, Hartman IZ, Narayan K, Kim A. Conformational heterogeneity of MHC class II induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection. Immunologic Research. 47: 56-64. PMID 20066513 DOI: 10.1007/S12026-009-8138-1  0.855
2010 Sadegh-Nasseri S, Dalai SK, Korb Ferris LC, Mirshahidi S. Suboptimal engagement of the T-cell receptor by a variety of peptide-MHC ligands triggers T-cell anergy. Immunology. 129: 1-7. PMID 20002785 DOI: 10.1111/J.1365-2567.2009.03206.X  0.848
2009 Narayan K, Su KW, Chou CL, Khoruzhenko S, Sadegh-Nasseri S. HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1. Molecular Immunology. 46: 3157-62. PMID 19647320 DOI: 10.1016/J.Molimm.2009.07.001  0.859
2009 Narayan K, Perkins EM, Murphy GE, Dalai SK, Edidin M, Subramaniam S, Sadegh-Nasseri S. Staphylococcal enterotoxin A induces small clusters of HLA-DR1 on B cells. Plos One. 4: e6188. PMID 19587800 DOI: 10.1371/Journal.Pone.0006188  0.837
2008 Dalai SK, Mirshahidi S, Morrot A, Zavala F, Sadegh-Nasseri S. Anergy in memory CD4+ T cells is induced by B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 3221-31. PMID 18713993 DOI: 10.4049/Jimmunol.181.5.3221  0.83
2008 Sadegh-Nasseri S, Chen M, Narayan K, Bouvier M. The convergent roles of tapasin and HLA-DM in antigen presentation. Trends in Immunology. 29: 141-7. PMID 18261958 DOI: 10.1016/J.It.2008.01.001  0.879
2008 Chou CL, Mirshahidi S, Su KW, Kim A, Narayan K, Khoruzhenko S, Xu M, Sadegh-Nasseri S. Short peptide sequences mimic HLA-DM functions. Molecular Immunology. 45: 1935-43. PMID 18054387 DOI: 10.1016/J.Molimm.2007.10.033  0.85
2007 Narayan K, Chou CL, Kim A, Hartman IZ, Dalai S, Khoruzhenko S, Sadegh-Nasseri S. HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes. Nature Immunology. 8: 92-100. PMID 17143275 DOI: 10.1038/Ni1414  0.821
2004 Mirshahidi S, Ferris LC, Sadegh-Nasseri S. The magnitude of TCR engagement is a critical predictor of T cell anergy or activation. Journal of Immunology (Baltimore, Md. : 1950). 172: 5346-55. PMID 15100274 DOI: 10.4049/Jimmunol.172.9.5346  0.789
2003 Fang M, Tao YX, He F, Zhang M, Levine CF, Mao P, Tao F, Chou CL, Sadegh-Nasseri S, Johns RA. Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics. The Journal of Biological Chemistry. 278: 36669-75. PMID 12853458 DOI: 10.1074/Jbc.M303520200  0.707
2001 Mirshahidi S, Huang C, Sadegh-Nasseri S. Anergy in peripheral memory CD4+ T cells induced by low avidity engagement of T cell receptor Journal of Experimental Medicine. 194: 719-731. PMID 11560989 DOI: 10.1084/Jem.194.6.719  0.746
2000 Chou CL, Sadegh-Nasseri S. HLA-DM recognizes the flexible conformation of major histocompatibility complex class II. The Journal of Experimental Medicine. 192: 1697-706. PMID 11120767 DOI: 10.1084/Jem.192.12.1697  0.761
2000 Sato AK, Zarutskie JA, Rushe MM, Lomakin A, Natarajan SK, Sadegh-Nasseri S, Benedek GB, Stern LJ. Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1. The Journal of Biological Chemistry. 275: 2165-73. PMID 10636922 DOI: 10.1074/Jbc.275.3.2165  0.832
1999 Korb LC, Mirshahidi S, Ramyar K, Sadighi Akha AA, Sadegh-Nasseri S. Induction of T cell anergy by low numbers of agonist ligands Journal of Immunology. 162: 6401-6409. PMID 10352253  0.448
1999 Natarajan SK, Assadi M, Sadegh-Nasseri S. Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides Journal of Immunology. 162: 4030-4036. PMID 10201925  0.468
1999 Natarajan SK, Stern LJ, Sadegh-Nasseri S. Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1. Journal of Immunology (Baltimore, Md. : 1950). 162: 3463-70. PMID 10092802  0.641
1997 Zhu X, Bavari S, Ulrich R, Sadegh-Nasseri S, Ferrone S, McHugh L, Mage M. A recombinant single-chain human class II MHC molecule (HLA-DR1) as a covalently linked heterotrimer of α chain, β chain, and antigenic peptide, with immunogenicity in vitro and reduced affinity for bacterial superantigens European Journal of Immunology. 27: 1933-1941. PMID 9295029 DOI: 10.1002/Eji.1830270817  0.625
1996 German RN, Castellino F, Han R, Reis e Sousa C, Romagnoli P, Sadegh-Nasseri S, Zhong GM. Processing and presentation of endocytically acquired protein antigens by MHC class II and class I molecules. Immunological Reviews. 151: 5-30. PMID 8872483 DOI: 10.1111/J.1600-065X.1996.Tb00701.X  0.434
1996 Zhu X, Sadegh-Nasseri S, Bavari S, Ulrich RG, Mage M. Recombinant single chain human HLA-DR1 molecules as biologically active covalently linked heterotrimers of antigenic peptide, beta chain, and alpha chain Faseb Journal. 10.  0.405
1995 Nauss JL, Sadegh-Nasseri S. Accuracy of a structural homology model for a class ii Journal of Biomolecular Structure and Dynamics. 12: 1213-1233. PMID 7669268 DOI: 10.1080/07391102.1995.10508808  0.428
1995 Park SJ, Sadegh-Nasseri S, Wiley DC. Invariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1. Proceedings of the National Academy of Sciences of the United States of America. 92: 11289-93. PMID 7479981 DOI: 10.1073/Pnas.92.24.11289  0.693
1994 Sadegh-Nasseri S, Stern LJ, Wiley DC, Germain RN. MHC class II function preserved by low-affinity peptide interactions preceding stable binding. Nature. 370: 647-50. PMID 8065450 DOI: 10.1038/370647A0  0.835
1993 Wu S, Yang Y, Sadegh-Nasseri S, Ashwell JD. Use of bispecific heteroconjugated antibodies (anti-T cell antigen receptor × anti-MHC class II) to study activation of T cells with a full length or truncated antigen receptor ζ-chain Journal of Immunology. 150: 2211-2221. PMID 8450208  0.466
1993 Boehncke WH, Takeshita T, Pendleton CD, Houghten RA, Sadegh-Nasseri S, Racioppi L, Berzofsky JA, Germain RN. The Importance of Dominant Negative Effects of Amino Acid Side Chain Substitution in Peptide-MHC Molecule Interactions and T Cell Recognition Journal of Immunology. 150: 331341.  0.521
1992 Sadegh-Nasseri S, Germain RN. How MHC class II molecules work: peptide-dependent completion of protein folding Immunology Today. 13: 43-46. PMID 1533524 DOI: 10.1016/0167-5699(92)90131-P  0.702
1991 Sadegh-Nasseri S, Germain RN. A role for peptide in determining MHC class II structure Nature. 353: 167-170. PMID 1653903 DOI: 10.1038/353167A0  0.718
1989 Sadegh-Nasseri S, McConnell HM. A kinetic intermediate in the reaction of an antigenic peptide and I-Ek. Nature. 337: 274-6. PMID 2536141 DOI: 10.1038/337274a0  0.667
1988 Sadegh-Nasseri S, Phipps RP. Immunogenic presentation of an immunoglobulin 'tolerogen' requires interleukin 2 European Journal of Immunology. 18: 417-423. PMID 2451614 DOI: 10.1002/Eji.1830180315  0.536
1987 Gammon G, Shastri N, Cogswell J, Wilbur S, Sadegh-Nasseri S, Krzych U, Miller A, Sercarz E. The choice of T-cell epitopes utilized on a protein antigen depends on multiple factors distant from, as well as at the determinant site Immunological Reviews. 98: 53-73. PMID 2443442 DOI: 10.1111/J.1600-065X.1987.Tb00519.X  0.726
1984 Sadegh-Nasseri S, Kipp DE, Taylor BA, Miller A, Sercarz E. Selective reversal of H-2 linked genetic unresponsiveness to lysozymes. I. Non-H-2 gene(s) closely linked to the Ir-2 locus on chromosome 2 permit(s) an antilysozyme response in H-2b mice. Immunogenetics. 20: 535-46. PMID 6437975 DOI: 10.1007/Bf00364356  0.506
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