| Year |
Citation |
Score |
| 2024 |
Vervuurt M, Schrader JM, de Kort AM, Kersten I, Wessels HJCT, Klijn CJM, Schreuder FHBM, Kuiperij HB, Gloerich J, Van Nostrand WE, Verbeek MM. Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients. Acta Neuropathologica Communications. 12: 6. PMID 38191511 DOI: 10.1186/s40478-023-01698-4 |
0.323 |
|
| 2023 |
Ambi A, Stanisavljevic A, Victor TW, Lowery AW, Davis J, Van Nostrand WE, Miller LM. Evaluation of Copper Chelation Therapy in a Transgenic Rat Model of Cerebral Amyloid Angiopathy. Acs Chemical Neuroscience. PMID 36651175 DOI: 10.1021/acschemneuro.2c00483 |
0.439 |
|
| 2022 |
Zhu X, Schrader JM, Irizarry BA, Smith SO, Van Nostrand WE. Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Biomedicines. 10. PMID 36428550 DOI: 10.3390/biomedicines10112982 |
0.474 |
|
| 2022 |
Davis J, Xu F, Zhu X, Van Nostrand WE. rTg-D: A novel transgenic rat model of cerebral amyloid angiopathy Type-2. Cerebral Circulation - Cognition and Behavior. 3: 100133. PMID 36324401 DOI: 10.1016/j.cccb.2022.100133 |
0.349 |
|
| 2022 |
Rajpoot J, Crooks EJ, Irizarry BA, Amundson A, Van Nostrand WE, Smith SO. Insights into Cerebral Amyloid Angiopathy Type 1 and Type 2 from Comparisons of the Fibrillar Assembly and Stability of the Aβ40-Iowa and Aβ40-Dutch Peptides. Biochemistry. PMID 35666749 DOI: 10.1021/acs.biochem.1c00781 |
0.563 |
|
| 2022 |
Stanisavljevic A, Schrader JM, Zhu X, Mattar JM, Hanks A, Xu F, Majchrzak M, Robinson JK, Van Nostrand WE. Impact of Non-pharmacological Chronic Hypertension on a Transgenic Rat Model of Cerebral Amyloid Angiopathy. Frontiers in Neuroscience. 16: 811371. PMID 35368255 DOI: 10.3389/fnins.2022.811371 |
0.308 |
|
| 2022 |
Vervuurt M, Zhu X, Schrader J, de Kort AM, Marques TM, Kersten I, Peters van Ton AM, Abdo WF, Schreuder FHBM, Rasing I, Terwindt GM, Wermer MJH, Greenberg SM, Klijn CJM, Kuiperij HB, ... Van Nostrand WE, et al. Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy. Neuropathology and Applied Neurobiology. e12804. PMID 35266166 DOI: 10.1111/nan.12804 |
0.386 |
|
| 2021 |
De Kort AM, Kuiperij HB, Kersten I, Versleijen AAM, Schreuder FHBM, Van Nostrand WE, Greenberg SM, Klijn CJM, Claassen JAHR, Verbeek MM. Normal cerebrospinal fluid concentrations of PDGFRβ in patients with cerebral amyloid angiopathy and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34874603 DOI: 10.1002/alz.12506 |
0.366 |
|
| 2021 |
Irizarry BA, Davis J, Zhu X, Boon BDC, Rozemuller AJM, Van Nostrand WE, Smith SO. Human cerebral vascular amyloid contains both anti-parallel and parallel in-register Aβ40 fibrils. The Journal of Biological Chemistry. 101259. PMID 34599967 DOI: 10.1016/j.jbc.2021.101259 |
0.531 |
|
| 2021 |
Schrader JM, Xu F, Van Nostrand WE. Distinct brain regional proteome changes in the rTg-DI rat model of cerebral amyloid angiopathy. Journal of Neurochemistry. PMID 34218440 DOI: 10.1111/jnc.15463 |
0.359 |
|
| 2021 |
Fu Z, Van Nostrand WE, Smith SO. Anti-Parallel β-Hairpin Structure in Soluble Aβ Oligomers of Aβ40-Dutch and Aβ40-Iowa. International Journal of Molecular Sciences. 22. PMID 33513738 DOI: 10.3390/ijms22031225 |
0.512 |
|
| 2020 |
Boon BDC, Bulk M, Jonker AJ, Morrema THJ, van den Berg E, Popovic M, Walter J, Kumar S, van der Lee SJ, Holstege H, Zhu X, Van Nostrand WE, Natté R, van der Weerd L, Bouwman FH, et al. The coarse-grained plaque: a divergent Aβ plaque-type in early-onset Alzheimer's disease. Acta Neuropathologica. PMID 32926214 DOI: 10.1007/s00401-020-02198-8 |
0.453 |
|
| 2020 |
Crooks EJ, Irizarry BA, Ziliox M, Kawakami T, Victor TW, Xu F, Hojo H, Chiu K, Simmerling C, Van Nostrand WE, Smith SO, Miller LM. Copper stabilizes antiparallel β-sheet fibrils of the amyloid β40 (Aβ40)-Iowa variant. The Journal of Biological Chemistry. PMID 32376688 DOI: 10.1074/Jbc.Ra119.011955 |
0.55 |
|
| 2020 |
Popescu DL, Van Nostrand WE, Robinson JK. Longitudinal Cognitive Decline in a Novel Rodent Model of Cerebral Amyloid Angiopathy Type-1. International Journal of Molecular Sciences. 21. PMID 32231123 DOI: 10.3390/Ijms21072348 |
0.426 |
|
| 2020 |
Zhu X, Hatfield J, Sullivan JK, Xu F, Van Nostrand WE. Robust neuroinflammation and perivascular pathology in rTg-DI rats, a novel model of microvascular cerebral amyloid angiopathy. Journal of Neuroinflammation. 17: 78. PMID 32127016 DOI: 10.1186/s12974-020-01755-y |
0.361 |
|
| 2020 |
Zhu X, Victor TW, Ambi A, Sullivan JK, Hatfield J, Xu F, Miller LM, Van Nostrand WE. Copper accumulation and the effect of chelation treatment on cerebral amyloid angiopathy compared to parenchymal amyloid plaques. Metallomics : Integrated Biometal Science. PMID 32104807 DOI: 10.1039/c9mt00306a |
0.469 |
|
| 2020 |
Robison LS, Francis N, Popescu DL, Anderson ME, Hatfield J, Xu F, Anderson BJ, Van Nostrand WE, Robinson JK. Environmental Enrichment: Disentangling the Influence of Novelty, Social, and Physical Activity on Cerebral Amyloid Angiopathy in a Transgenic Mouse Model. International Journal of Molecular Sciences. 21. PMID 32012921 DOI: 10.3390/Ijms21030843 |
0.328 |
|
| 2019 |
Robison LS, Popescu DL, Anderson ME, Francis N, Hatfield J, Sullivan JK, Beigelman SI, Xu F, Anderson BJ, Van Nostrand WE, Robinson JK. Long-term voluntary wheel running does not alter vascular amyloid burden but reduces neuroinflammation in the Tg-SwDI mouse model of cerebral amyloid angiopathy. Journal of Neuroinflammation. 16: 144. PMID 31296239 DOI: 10.1186/S12974-019-1534-0 |
0.462 |
|
| 2019 |
Chen CD, Zeldich E, Khodr C, Camara K, Tung TY, Lauder EC, Mullen P, Polanco TJ, Liu YY, Zeldich D, Xia W, Van Nostrand WE, Brown LE, Porco JA, Abraham CR. Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling. Journal of Alzheimer's Disease : Jad. 67: 1089-1106. PMID 30776010 DOI: 10.3233/Jad-180923 |
0.41 |
|
| 2018 |
Davis J, Xu F, Hatfield J, Lee H, Hoos MD, Popescu D, Crooks E, Kim R, Smith SO, Robinson JK, Benveniste H, Van Nostrand WE. A Novel Transgenic Rat Model of Robust Cerebral Microvascular Amyloid with Prominent Vasculopathy. The American Journal of Pathology. PMID 30446159 DOI: 10.1016/J.Ajpath.2018.07.030 |
0.787 |
|
| 2017 |
Jäkel L, Van Nostrand WE, Nicoll JAR, Werring DJ, Verbeek MM. Animal models of cerebral amyloid angiopathy. Clinical Science (London, England : 1979). 131: 2469-2488. PMID 28963121 DOI: 10.1042/CS20170033 |
0.368 |
|
| 2017 |
Xu F, Davis J, Hoos M, Van Nostrand WE. Mutation of the Kunitz-type proteinase inhibitor domain in the amyloid β-protein precursor abolishes its anti-thrombotic properties in vivo. Thrombosis Research. 155: 58-64. PMID 28499154 DOI: 10.1016/J.Thromres.2017.05.003 |
0.771 |
|
| 2016 |
Xu F, Fu Z, Dass S, Kotarba AE, Davis J, Smith SO, Van Nostrand WE. Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure. Nature Communications. 7: 13527. PMID 27869115 DOI: 10.1038/Ncomms13527 |
0.572 |
|
| 2016 |
Anderson M, Xu F, Ou-Yang MH, Davis J, Van Nostrand WE, Robinson JK. Intensive 'Brain Training' Intervention Fails to Reduce Amyloid Pathologies or Cognitive Deficits in Transgenic Mouse Models of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27767989 DOI: 10.3233/Jad-160674 |
0.348 |
|
| 2016 |
Xu F, Van Nostrand WE. Data on thrombotic ischemic lesions in the presence or absence of amyloid ß-protein precursor or its homolog amyloid precursor-like protein-2 in mice. Data in Brief. 6: 149-52. PMID 26858980 DOI: 10.1016/j.dib.2015.11.050 |
0.375 |
|
| 2016 |
Van Nostrand WE. The influence of the amyloid ß-protein and its precursor in modulating cerebral hemostasis. Biochimica Et Biophysica Acta. 1862: 1018-26. PMID 26519139 DOI: 10.1016/j.bbadis.2015.10.020 |
0.316 |
|
| 2015 |
Fu Z, Aucoin D, Davis J, Van Nostrand WE, Smith SO. Mechanism of Nucleated Conformational Conversion of Aβ42. Biochemistry. 54: 4197-207. PMID 26069943 DOI: 10.1021/Acs.Biochem.5B00467 |
0.363 |
|
| 2015 |
Ou-Yang MH, Xu F, Liao MC, Davis J, Robinson JK, Van Nostrand WE. The N-terminal region of myelin basic protein reduces fibrillar amyloid-β deposition in Tg-5xFAD mice. Neurobiology of Aging. 36: 801-11. PMID 25457550 DOI: 10.1016/J.Neurobiolaging.2014.10.006 |
0.726 |
|
| 2014 |
Fu Z, Aucoin D, Ahmed M, Ziliox M, Van Nostrand WE, Smith SO. Capping of aβ42 oligomers by small molecule inhibitors. Biochemistry. 53: 7893-903. PMID 25422864 DOI: 10.1021/Bi500910B |
0.438 |
|
| 2014 |
Xu F, Kotarba AE, Ou-Yang MH, Fu Z, Davis J, Smith SO, Van Nostrand WE. Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice. The Journal of Biological Chemistry. 289: 17895-908. PMID 24828504 DOI: 10.1074/Jbc.M113.536565 |
0.55 |
|
| 2014 |
Park L, Koizumi K, El Jamal S, Zhou P, Previti ML, Van Nostrand WE, Carlson G, Iadecola C. Age-dependent neurovascular dysfunction and damage in a mouse model of cerebral amyloid angiopathy. Stroke; a Journal of Cerebral Circulation. 45: 1815-21. PMID 24781082 DOI: 10.1161/Strokeaha.114.005179 |
0.484 |
|
| 2014 |
Xu W, Xu F, Anderson ME, Kotarba AE, Davis J, Robinson JK, Van Nostrand WE. Cerebral microvascular rather than parenchymal amyloid-β protein pathology promotes early cognitive impairment in transgenic mice. Journal of Alzheimer's Disease : Jad. 38: 621-32. PMID 24037035 DOI: 10.3233/Jad-130758 |
0.433 |
|
| 2013 |
Ou-Yang MH, Van Nostrand WE. The absence of myelin basic protein promotes neuroinflammation and reduces amyloid β-protein accumulation in Tg-5xFAD mice. Journal of Neuroinflammation. 10: 134. PMID 24188129 DOI: 10.1186/1742-2094-10-134 |
0.524 |
|
| 2013 |
Hu ZI, Kotarba AM, Van Nostrand WE. Absence of Nitric Oxide Synthase 3 Increases Amyloid β-Protein Pathology in Tg-5xFAD Mice. Neuroscience and Medicine. 4: 84-91. PMID 24159423 DOI: 10.4236/nm.2013.42013 |
0.672 |
|
| 2013 |
Kotarba AE, Aucoin D, Hoos MD, Smith SO, Van Nostrand WE. Fine mapping of the amyloid β-protein binding site on myelin basic protein. Biochemistry. 52: 2565-73. PMID 23510371 DOI: 10.1021/Bi4001936 |
0.798 |
|
| 2013 |
Park L, Zhou P, Koizumi K, El Jamal S, Previti ML, Van Nostrand WE, Carlson G, Iadecola C. Brain and circulating levels of Aβ1-40 differentially contribute to vasomotor dysfunction in the mouse brain. Stroke; a Journal of Cerebral Circulation. 44: 198-204. PMID 23204056 DOI: 10.1161/Strokeaha.112.670976 |
0.384 |
|
| 2012 |
Xu F, Vitek MP, Colton CA, Previti ML, Davis J, Van Nostrand WE. Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice. Journal of Alzheimer's Disease : Jad. 31: 359-69. PMID 22635103 DOI: 10.3233/JAD-2012-120421 |
0.429 |
|
| 2012 |
Ladiwala AR, Litt J, Kane RS, Aucoin DS, Smith SO, Ranjan S, Davis J, Van Nostrand WE, Tessier PM. Conformational differences between two amyloid β oligomers of similar size and dissimilar toxicity. The Journal of Biological Chemistry. 287: 24765-73. PMID 22547072 DOI: 10.1074/Jbc.M111.329763 |
0.502 |
|
| 2012 |
Vitek MP, Christensen DJ, Wilcock D, Davis J, Van Nostrand WE, Li FQ, Colton CA. APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. Neuro-Degenerative Diseases. 10: 122-6. PMID 22326991 DOI: 10.1159/000334914 |
0.363 |
|
| 2012 |
Van Nostrand WE, Davis J, Previti ML, Xu F. Clearance of amyloid-β protein deposits in transgenic mice following focal cerebral ischemia Neurodegenerative Diseases. 10: 108-111. PMID 22269180 DOI: 10.1159/000334763 |
0.443 |
|
| 2010 |
Robert R, Lefranc MP, Ghochikyan A, Agadjanyan MG, Cribbs DH, Van Nostrand WE, Wark KL, Dolezal O. Restricted V gene usage and VH/VL pairing of mouse humoral response against the N-terminal immunodominant epitope of the amyloid β peptide. Molecular Immunology. 48: 59-72. PMID 20970857 DOI: 10.1016/j.molimm.2010.09.012 |
0.392 |
|
| 2010 |
Van Nostrand WE, Xu F, Rozemuller AJ, Colton CA. Enhanced capillary amyloid angiopathy-associated pathology in Tg-SwDI mice with deleted nitric oxide synthase 2. Stroke; a Journal of Cerebral Circulation. 41: S135-8. PMID 20876489 DOI: 10.1161/STROKEAHA.110.595272 |
0.513 |
|
| 2010 |
Liao MC, Hoos MD, Aucoin D, Ahmed M, Davis J, Smith SO, Van Nostrand WE. N-terminal domain of myelin basic protein inhibits amyloid beta-protein fibril assembly. The Journal of Biological Chemistry. 285: 35590-8. PMID 20807757 DOI: 10.1074/Jbc.M110.169599 |
0.801 |
|
| 2010 |
Ahmed M, Davis J, Aucoin D, Sato T, Ahuja S, Aimoto S, Elliott JI, Van Nostrand WE, Smith SO. Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils. Nature Structural & Molecular Biology. 17: 561-7. PMID 20383142 DOI: 10.1038/Nsmb.1799 |
0.496 |
|
| 2010 |
Liao MC, Van Nostrand WE. Degradation of soluble and fibrillar amyloid beta-protein by matrix metalloproteinase (MT1-MMP) in vitro. Biochemistry. 49: 1127-36. PMID 20050683 DOI: 10.1021/bi901994d |
0.65 |
|
| 2010 |
Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-β vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease (The Journal of Neuroscience (2009) (7957-7965)) Journal of Neuroscience. 30: 1197-1198. |
0.382 |
|
| 2009 |
Liao MC, Ahmed M, Smith SO, Van Nostrand WE. Degradation of amyloid beta protein by purified myelin basic protein. The Journal of Biological Chemistry. 284: 28917-25. PMID 19692707 DOI: 10.1074/Jbc.M109.050856 |
0.778 |
|
| 2009 |
Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7957-65. PMID 19553436 DOI: 10.1523/JNEUROSCI.1339-09.2009 |
0.4 |
|
| 2009 |
Xu F, Previti ML, Nieman MT, Davis J, Schmaier AH, Van Nostrand WE. AbetaPP/APLP2 family of Kunitz serine proteinase inhibitors regulate cerebral thrombosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5666-70. PMID 19403832 DOI: 10.1523/JNEUROSCI.0095-09.2009 |
0.463 |
|
| 2009 |
Hoos MD, Ahmed M, Smith SO, Van Nostrand WE. Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro. Biochemistry. 48: 4720-7. PMID 19385666 DOI: 10.1021/Bi900037S |
0.838 |
|
| 2009 |
Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells. Nature Cell Biology. 11: 143-53. PMID 19098903 DOI: 10.1038/Ncb1819 |
0.564 |
|
| 2008 |
Colton CA, Wilcock DM, Wink DA, Davis J, Van Nostrand WE, Vitek MP. The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP. Journal of Alzheimer's Disease : Jad. 15: 571-87. PMID 19096157 DOI: 10.3233/Jad-2008-15405 |
0.508 |
|
| 2008 |
Van Vickle GD, Esh CL, Daugs ID, Kokjohn TA, Kalback WM, Patton RL, Luehrs DC, Walker DG, Lue LF, Beach TG, Davis J, Van Nostrand WE, Castaño EM, Roher AE. Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy. The American Journal of Pathology. 173: 483-93. PMID 18599612 DOI: 10.2353/ajpath.2008.071191 |
0.575 |
|
| 2008 |
Xu F, Vitek MP, Colton CA, Previti ML, Gharkholonarehe N, Davis J, Van Nostrand WE. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5312-20. PMID 18480287 DOI: 10.1523/JNEUROSCI.1042-08.2008 |
0.566 |
|
| 2008 |
Wilcock DM, Lewis MR, Van Nostrand WE, Davis J, Previti ML, Gharkholonarehe N, Vitek MP, Colton CA. Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1537-45. PMID 18272675 DOI: 10.1523/JNEUROSCI.5066-07.2008 |
0.417 |
|
| 2007 |
Vasilevko V, Xu F, Previti ML, Van Nostrand WE, Cribbs DH. Experimental investigation of antibody-mediated clearance mechanisms of amyloid-beta in CNS of Tg-SwDI transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13376-83. PMID 18057195 DOI: 10.1523/JNEUROSCI.2788-07.2007 |
0.497 |
|
| 2007 |
Fan R, DeFilippis K, Van Nostrand WE. Induction of complement proteins in a mouse model for cerebral microvascular A beta deposition. Journal of Neuroinflammation. 4: 22. PMID 17877807 DOI: 10.1186/1742-2094-4-22 |
0.408 |
|
| 2007 |
Xu F, Previti ML, Van Nostrand WE. Increased severity of hemorrhage in transgenic mice expressing cerebral protease nexin-2/amyloid beta-protein precursor. Stroke; a Journal of Cerebral Circulation. 38: 2598-601. PMID 17656662 DOI: 10.1161/STROKEAHA.106.480103 |
0.454 |
|
| 2007 |
Fan R, Xu F, Previti ML, Davis J, Grande AM, Robinson JK, Van Nostrand WE. Minocycline reduces microglial activation and improves behavioral deficits in a transgenic model of cerebral microvascular amyloid. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3057-63. PMID 17376966 DOI: 10.1523/Jneurosci.4371-06.2007 |
0.49 |
|
| 2007 |
Xu F, Grande AM, Robinson JK, Previti ML, Vasek M, Davis J, Van Nostrand WE. Early-onset subicular microvascular amyloid and neuroinflammation correlate with behavioral deficits in vasculotropic mutant amyloid β-protein precursor transgenic mice Neuroscience. 146: 98-107. PMID 17331655 DOI: 10.1016/J.Neuroscience.2007.01.043 |
0.429 |
|
| 2007 |
Hoos MD, Ahmed M, Smith SO, Van Nostrand WE. Inhibition of familial cerebral amyloid angiopathy mutant amyloid beta-protein fibril assembly by myelin basic protein. The Journal of Biological Chemistry. 282: 9952-61. PMID 17259179 DOI: 10.1074/Jbc.M603494200 |
0.835 |
|
| 2007 |
Chow N, Bell RD, Deane R, Streb JW, Chen J, Brooks A, Van Nostrand W, Miano JM, Zlokovic BV. Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype. Proceedings of the National Academy of Sciences of the United States of America. 104: 823-8. PMID 17215356 DOI: 10.1073/Pnas.0608251104 |
0.456 |
|
| 2006 |
Yamamoto N, Van Nostrand WE, Yanagisawa K. Further evidence of local ganglioside-dependent amyloid beta-protein assembly in brain. Neuroreport. 17: 1735-7. PMID 17047463 DOI: 10.1097/01.wnr.0000239958.53072.14 |
0.519 |
|
| 2006 |
Carrasco J, Adlard P, Cotman C, Quintana A, Penkowa M, Xu F, Van Nostrand WE, Hidalgo J. Metallothionein-I and -III expression in animal models of Alzheimer disease. Neuroscience. 143: 911-22. PMID 17027170 DOI: 10.1016/J.Neuroscience.2006.08.054 |
0.41 |
|
| 2006 |
Colton CA, Mott RT, Sharpe H, Xu Q, Van Nostrand WE, Vitek MP. Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. Journal of Neuroinflammation. 3: 27. PMID 17005052 DOI: 10.1186/1742-2094-3-27 |
0.38 |
|
| 2006 |
Colton CA, Vitek MP, Wink DA, Xu Q, Cantillana V, Previti ML, Van Nostrand WE, Weinberg JB, Weinberg B, Dawson H. NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 12867-72. PMID 16908860 DOI: 10.1073/pnas.0601075103 |
0.566 |
|
| 2006 |
Burgess BL, McIsaac SA, Naus KE, Chan JY, Tansley GH, Yang J, Miao F, Ross CJ, van Eck M, Hayden MR, van Nostrand W, St George-Hyslop P, Westaway D, Wellington CL. Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma. Neurobiology of Disease. 24: 114-27. PMID 16899370 DOI: 10.1016/J.Nbd.2006.06.007 |
0.323 |
|
| 2006 |
Previti ML, Zhang W, Van Nostrand WE. Dexamethasone diminishes the pro-inflammatory and cytotoxic effects of amyloid beta-protein in cerebrovascular smooth muscle cells. Journal of Neuroinflammation. 3: 18. PMID 16887032 DOI: 10.1186/1742-2094-3-18 |
0.496 |
|
| 2006 |
Herzig MC, Van Nostrand WE, Jucker M. Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models. Brain Pathology (Zurich, Switzerland). 16: 40-54. PMID 16612981 DOI: 10.1111/j.1750-3639.2006.tb00560.x |
0.579 |
|
| 2006 |
Davis J, Xu F, Miao J, Previti ML, Romanov G, Ziegler K, Van Nostrand WE. Deficient cerebral clearance of vasculotropic mutant Dutch/Iowa Double A beta in human A betaPP transgenic mice. Neurobiology of Aging. 27: 946-54. PMID 16105708 DOI: 10.1016/j.neurobiolaging.2005.05.031 |
0.348 |
|
| 2005 |
Xu F, Davis J, Miao J, Previti ML, Romanov G, Ziegler K, Van Nostrand WE. Protease nexin-2/amyloid beta-protein precursor limits cerebral thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 18135-40. PMID 16330760 DOI: 10.1073/pnas.0507798102 |
0.478 |
|
| 2005 |
Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease. The Journal of Biological Chemistry. 280: 43243-56. PMID 16207707 DOI: 10.1074/Jbc.M508781200 |
0.493 |
|
| 2005 |
Miao J, Xu F, Davis J, Otte-Höller I, Verbeek MM, Van Nostrand WE. Cerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein. The American Journal of Pathology. 167: 505-15. PMID 16049335 |
0.584 |
|
| 2005 |
Miao J, Vitek MP, Xu F, Previti ML, Davis J, Van Nostrand WE. Reducing cerebral microvascular amyloid-beta protein deposition diminishes regional neuroinflammation in vasculotropic mutant amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6271-7. PMID 16000616 DOI: 10.1523/JNEUROSCI.1306-05.2005 |
0.619 |
|
| 2005 |
Wilhelmus MM, Otte-Höller I, Davis J, Van Nostrand WE, de Waal RM, Verbeek MM. Apolipoprotein E genotype regulates amyloid-beta cytotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3621-7. PMID 15814793 DOI: 10.1523/JNEUROSCI.4213-04.2005 |
0.529 |
|
| 2005 |
Yamamoto N, Hirabayashi Y, Amari M, Yamaguchi H, Romanov G, Van Nostrand WE, Yanagisawa K. Assembly of hereditary amyloid beta-protein variants in the presence of favorable gangliosides. Febs Letters. 579: 2185-90. PMID 15811339 DOI: 10.1016/j.febslet.2005.03.013 |
0.595 |
|
| 2005 |
Miao J, Xu F, Davis J, Otte-Höller I, Verbeek MM, Van Nostrand WE. Cerebral microvascular amyloid β protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid β precursor protein American Journal of Pathology. 167: 505-515. |
0.529 |
|
| 2004 |
Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, et al. LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms. Neuron. 43: 333-44. PMID 15294142 DOI: 10.1016/J.Neuron.2004.07.017 |
0.589 |
|
| 2004 |
Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, Zlokovic BV, Van Nostrand WE. Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor. The Journal of Biological Chemistry. 279: 20296-306. PMID 14985348 DOI: 10.1074/Jbc.M312946200 |
0.571 |
|
| 2003 |
Davis J, Wagner MR, Zhang W, Xu F, Van Nostrand WE. Amyloid beta-protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells. The Journal of Biological Chemistry. 278: 19054-61. PMID 12754271 DOI: 10.1074/jbc.M301398200 |
0.425 |
|
| 2003 |
Jung SS, Zhang W, Van Nostrand WE. Pathogenic A beta induces the expression and activation of matrix metalloproteinase-2 in human cerebrovascular smooth muscle cells. Journal of Neurochemistry. 85: 1208-15. PMID 12753080 DOI: 10.1046/j.1471-4159.2003.01745.x |
0.323 |
|
| 2003 |
Jung SS, Van Nostrand WE. Humanin rescues human cerebrovascular smooth muscle cells from Abeta-induced toxicity. Journal of Neurochemistry. 84: 266-72. PMID 12558989 DOI: 10.1046/j.1471-4159.2003.01524.x |
0.495 |
|
| 2002 |
Van Nostrand WE, Melchor JP, Romanov G, Zeigler K, Davis J. Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor. Annals of the New York Academy of Sciences. 977: 258-65. PMID 12480759 DOI: 10.1111/J.1749-6632.2002.Tb04824.X |
0.824 |
|
| 2002 |
Jung SS, Van Nostrand WE. Abeta does not induce oxidative stress in human cerebrovascular smooth muscle cells. Neuroreport. 13: 1309-12. PMID 12151793 |
0.417 |
|
| 2002 |
Van Nostrand WE, Melchor JP, Keane DM, Saporito-Irwin SM, Romanov G, Davis J, Xu F. Localization of a fibrillar amyloid beta-protein binding domain on its precursor. The Journal of Biological Chemistry. 277: 36392-8. PMID 12107175 DOI: 10.1074/jbc.M204676200 |
0.814 |
|
| 2001 |
Van Nostrand WE, Melchor JP. Disruption of pathologic amyloid beta-protein fibril assembly on the surface of cultured human cerebrovascular smooth muscle cells. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 8: 20-7. PMID 11676286 |
0.807 |
|
| 2001 |
Van Nostrand WE, Melchor JP, Cho HS, Greenberg SM, Rebeck GW. Pathogenic Effects of D23N Iowa Mutant Amyloid β-Protein Journal of Biological Chemistry. 276: 32860-32866. PMID 11441013 DOI: 10.1074/Jbc.M104135200 |
0.801 |
|
| 2000 |
Wagner MR, Keane DM, Melchor JP, Auspaker KR, Van Nostrand WE. Fibrillar amyloid beta-protein binds protease nexin-2/amyloid beta-protein precursor: stimulation of its inhibition of coagulation factor XIa. Biochemistry. 39: 7420-7. PMID 10858290 DOI: 10.1021/bi0002840 |
0.821 |
|
| 2000 |
Verbeek MM, Van Nostrand WE, Otte-Höller I, Wesseling P, De Waal RMW. Amyloid-β-induced degeneration of human brain pericytes is dependent on the apolipoprotein E genotype Annals of the New York Academy of Sciences. 903: 187-199. PMID 10818507 DOI: 10.1111/j.1749-6632.2000.tb06368.x |
0.463 |
|
| 2000 |
Van Nostrand WE, Melchor J, Wagner M, Davis J. Cerebrovascular smooth muscle cell surface fibrillar aβ Annals of the New York Academy of Sciences. 903: 89-96. PMID 10818493 DOI: 10.1111/J.1749-6632.2000.Tb06354.X |
0.78 |
|
| 2000 |
Melchor JP, McVoy L, Van Nostrand WE. Charge alterations of E22 enhance the pathogenic properties of the amyloid beta-protein. Journal of Neurochemistry. 74: 2209-12. PMID 10800967 DOI: 10.1046/J.1471-4159.2000.0742209.X |
0.813 |
|
| 2000 |
Melchor JP, Van Nostrand WE. Fibrillar amyloid beta-protein mediates the pathologic accumulation of its secreted precursor in human cerebrovascular smooth muscle cells. The Journal of Biological Chemistry. 275: 9782-91. PMID 10734132 DOI: 10.1074/Jbc.275.13.9782 |
0.807 |
|
| 1999 |
Davis J, Cribbs DH, Cotman CW, Van Nostrand WE. Pathogenic amyloid beta-protein induces apoptosis in cultured human cerebrovascular smooth muscle cells. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 6: 157-64. PMID 10524279 DOI: 10.3109/13506129909007321 |
0.402 |
|
| 1999 |
Van Nostrand WE, Porter M. Plasmin cleavage of the amyloid β-protein: Alteration of secondary structure and stimulation of tissue plasminogen activator activity Biochemistry. 38: 11570-11576. PMID 10471309 DOI: 10.1021/bi990610f |
0.473 |
|
| 1998 |
Van Nostrand WE, Melchor JP, Ruffini L. Pathologic amyloid beta-protein cell surface fibril assembly on cultured human cerebrovascular smooth muscle cells. Journal of Neurochemistry. 70: 216-23. PMID 9422365 DOI: 10.1046/J.1471-4159.1998.70010216.X |
0.734 |
|
| 1997 |
Verbeek MM, De Waal RMW, Schipper JJ, Van Nostrand WE. Rapid degeneration of cultured human brain pericytes by amyloid β protein Journal of Neurochemistry. 68: 1135-1141. PMID 9048759 |
0.51 |
|
| 1997 |
Verbeek MM, De Waal RMW, Van Nostrand WE. Aβ-induced cytotoxicity: A model for cerebral vascular degeneration in Alzheimer's disease Endothelium: Journal of Endothelial Cell Research. 5: 355. |
0.339 |
|
| 1997 |
Saporito-Irwin SM, Thinakaran G, Ruffini L, Sisodia SS, Van Nostrand WE. Amyloid ß-protein stimulates parallel increases in cellular levels of its precursor and amyloid precursor-like protein 2 (APLP2) in human cerebrovascular smooth muscle cells Amyloid. 4: 54-60. |
0.46 |
|
| 1996 |
Van Nostrand WE, Davis-Salinas J, Saporito-Irwin SM. Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders Annals of the New York Academy of Sciences. 777: 297-302. PMID 8624102 |
0.522 |
|
| 1996 |
Davis J, Van Nostrand WE. Enhanced pathologic properties of Dutch-type mutant amyloid β-protein Proceedings of the National Academy of Sciences of the United States of America. 93: 2996-3000. PMID 8610157 DOI: 10.1073/pnas.93.7.2996 |
0.54 |
|
| 1995 |
Choi BH, Kim RC, Vaughan PJ, Lau A, Van Nostrand WE, Cotman CW, Cunningham DD. Decreases in protease nexins in Alzheimer's disease brain. Neurobiology of Aging. 16: 557-62. PMID 8544905 DOI: 10.1016/0197-4580(95)00060-R |
0.405 |
|
| 1995 |
Van Nostrand WE. Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid β-Protein precursor Thrombosis Research. 78: 43-53. PMID 7778065 DOI: 10.1016/0049-3848(95)00033-X |
0.317 |
|
| 1995 |
Davis-Salinas J, Van Nostrand WE. Amyloid β-protein aggregation nullifies its pathologic properties in cultured cerebrovascular smooth muscle cells Journal of Biological Chemistry. 270: 20887-20890. PMID 7673109 DOI: 10.1074/jbc.270.36.20887 |
0.528 |
|
| 1995 |
Veerhuis R, van der Valk P, Janssen I, Zhan SS, Eikelenboom P, Van Nostrand WE. Complement activation in amyloid plaques in Alzheimer's disease brains does not proceed further than C3 Virchows Archiv. 426: 603-610. PMID 7655742 DOI: 10.1007/Bf00192116 |
0.351 |
|
| 1995 |
Gregori L, Fuchs C, Figueiredo-Pereira ME, Van Nostrand WE, Goldgaber D. Amyloid β-protein inhibits ubiquitin-dependent protein degradation in vitro Journal of Biological Chemistry. 270: 19702-19708. PMID 7649980 DOI: 10.1074/jbc.270.34.19702 |
0.493 |
|
| 1995 |
Davis-Salinas J, Saporito-Irwin SM, Cotman CW, Van Nostrand WE. Amyloid beta-protein induces its own production in cultured degenerating cerebrovascular smooth muscle cells. Journal of Neurochemistry. 65: 931-4. PMID 7616257 DOI: 10.1046/J.1471-4159.1995.65020931.X |
0.343 |
|
| 1995 |
Zhan SS, Kamphorst W, Van Nostrand WE, Eikelenboom P. Distribution of neuronal growth-promoting factors and cytoskeletal proteins in altered neurites in Alzheimer's disease and non-demented elderly Acta Neuropathologica. 89: 356-362. PMID 7610767 DOI: 10.1007/Bf00309629 |
0.416 |
|
| 1995 |
Saporito-Irwin SM, Van Nostrand WE. Coagulation factor XIa cleaves the RHDS sequence and abolishes the cell adhesive properties of the amyloid β-protein Journal of Biological Chemistry. 270: 26265-26269. PMID 7592834 DOI: 10.1074/jbc.270.44.26265 |
0.482 |
|
| 1994 |
Davis-Salinas J, Saporito-Irwin SM, Donovan FM, Cunningham DD, Van Nostrand WE. Thrombin receptor activation induces secretion and nonamyloidogenic processing of amyloid beta-protein precursor. The Journal of Biological Chemistry. 269: 22623-7. PMID 8077213 |
0.328 |
|
| 1994 |
Van Nostrand WE, Schmaier AH, Neiditch BR, Siegel RS, Raschke WC, Sisodia SS, Wagner SL. Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid beta-protein precursor-like protein-2. Biochimica Et Biophysica Acta. 1209: 165-70. PMID 7811686 DOI: 10.1016/0167-4838(94)90180-5 |
0.324 |
|
| 1993 |
Kibbey MC, Jucker M, Weeks BS, Neve RL, Van Nostrand WE, Kleinman HK. β-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin Proceedings of the National Academy of Sciences of the United States of America. 90: 10150-10153. PMID 8234269 DOI: 10.1073/pnas.90.21.10150 |
0.452 |
|
| 1993 |
Rozemuller AJM, Roos RAC, Bots GTAM, Kamphorst W, Eikelenboom P, Van Nostrand WE. Distribution of β/A4 protein and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease American Journal of Pathology. 142: 1449-1457. PMID 7684195 |
0.478 |
|
| 1992 |
van Nostrand WE, Wagner SL, Haan J, Bakker E, Roos RAC. Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis–dutch type share a decrease in cerebrospinal fluid levels of amyloid β‐protein precursor Annals of Neurology. 32: 215-218. PMID 1510361 DOI: 10.1002/ana.410320214 |
0.425 |
|
| 1992 |
Cummings BJ, Su JH, Geddes JW, Van Nostrand WE, Wagner SL, Cunningham DD, Cotman CW. Aggregation of the amyloid precursor protein within degenerating neurons and dystrophic neurites in Alzheimer's disease. Neuroscience. 48: 763-77. PMID 1378573 DOI: 10.1016/0306-4522(92)90265-4 |
0.524 |
|
| 1992 |
Farlow M, Ghetti B, Benson MD, Farrow JS, van Nostrand WE, Wagner SL. Low cerebrospinal-fluid concentrations of soluble amyloid beta-protein precursor in hereditary Alzheimer's disease. Lancet. 340: 453-4. PMID 1354785 DOI: 10.1016/0140-6736(92)91771-Y |
0.439 |
|
| 1992 |
VAN NOSTRAND WE, SCHMAIER AH, WAGNER SL. Potential Role of Protease Nexin‐2/Amyloid β‐Protein Precursor as a Cerebral Anticoagulant Annals of the New York Academy of Sciences. 674: 243-252. PMID 1288367 DOI: 10.1111/j.1749-6632.1992.tb27493.x |
0.462 |
|
| 1991 |
Abraham CR, Driscoll J, Potter H, Van Nostrand WE, Tempst P. A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid beta-protein. Biochemical and Biophysical Research Communications. 174: 790-6. PMID 1993072 DOI: 10.1016/0006-291X(91)91487-W |
0.437 |
|
| 1991 |
Bhasin R, Van Nostrand WE, Saitoh T, Donets MA, Barnes EA, Quitschke WW, Goldgaber D. Expression of active secreted forms of human amyloid beta-protein precursor by recombinant baculovirus-infected insect cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10307-11. PMID 1946449 |
0.451 |
|
| 1991 |
Van Nostrand WE, Farrow JS, Wagner SL, Bhasin R, Goldgaber D, Cotman CW, Cunningham DD. The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2. Proceedings of the National Academy of Sciences of the United States of America. 88: 10302-6. PMID 1946448 DOI: 10.1073/Pnas.88.22.10302 |
0.458 |
|
| 1991 |
Van Nostrand WE, Schmaier AH, Farrow JS, Cines DB, Cunningham DD. Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein. Biochemical and Biophysical Research Communications. 175: 15-21. PMID 1900151 DOI: 10.1016/S0006-291X(05)81193-3 |
0.377 |
|
| 1991 |
Abraham CR, Razzaboni BL, Sisodia SS, Koo EH, Price DL, Van Nostrand WE, Papastoitsis G. Studies on the proteolytic degradation of the beta-protein precursor by proteases purified from Alzheimer's disease brain. Annals of the New York Academy of Sciences. 640: 161-5. PMID 1776735 DOI: 10.1111/J.1749-6632.1991.Tb00209.X |
0.413 |
|
| 1991 |
Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. Platelet protease nexin-2/amyloid beta-protein precursor. Possible pathologic and physiologic functions. Annals of the New York Academy of Sciences. 640: 140-4. PMID 1776731 DOI: 10.1111/J.1749-6632.1991.Tb00205.X |
0.5 |
|
| 1990 |
Van Nostrand WE, Wagner SL, Farrow JS, Cunningham DD. Immunopurification and protease inhibitory properties of protease nexin-2/amyloid beta-protein precursor. The Journal of Biological Chemistry. 265: 9591-4. PMID 2112543 |
0.397 |
|
| 1990 |
Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein. Science (New York, N.Y.). 248: 745-8. PMID 2110384 DOI: 10.1126/Science.2110384 |
0.359 |
|
| 1989 |
Van Nostrand WE, Wagner SL, Suzuki M, Choi BH, Farrow JS, Geddes JW, Cotman CW, Cunningham DD. Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor. Nature. 341: 546-9. PMID 2507928 DOI: 10.1038/341546A0 |
0.39 |
|
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