Patrick J. Marsac, Ph.D. - Publications

Affiliations: 
2007 Industrial and Physical Pharmacy Purdue University, West Lafayette, IN, United States 
Area:
Pharmacy

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lu X, Li M, Arce FA, Ling J, Setiawan N, Wang Y, Shi X, Campbell HR, Nethercott MJ, Xu W, Munson EJ, Marsac PJ, Su Y. Mechanistic Investigation of Drug Supersaturation in the Presence of Polysorbates as Solubilizing Additives by Solution Nuclear Magnetic Resonance Spectroscopy. Molecular Pharmaceutics. PMID 34761934 DOI: 10.1021/acs.molpharmaceut.1c00477  0.732
2020 Arce FA, Setiawan N, Campbell HR, Lu X, Nethercott MJ, Bummer P, Su Y, Marsac PJ. Towards Developing Discriminating Dissolution Methods for Formulations Containing Nano-Particulates in Solution; The Impact of Particle Drift and Drug Activity in Solution. Molecular Pharmaceutics. PMID 32965123 DOI: 10.1021/acs.molpharmaceut.0c00599  0.733
2020 Defrese M, Farmer MA, Long Y, Timmerman L, Bae Y, Marsac PJ. Approaches to understand the solution state organization of spray dried dispersion feed solutions and its translation to the solid state. Molecular Pharmaceutics. PMID 32965120 DOI: 10.1021/acs.molpharmaceut.0c00729  0.749
2018 Alin J, Setiawan N, Defrese M, DiNunzio J, Lau H, Lupton L, Xi H, Su Y, Nie H, Hesse N, Taylor LS, Marsac PJ. A novel approach for measuring room temperature enthalpy of mixing and associated solubility estimation of a drug in a polymer matrix Polymer. 135: 50-60. DOI: 10.1016/J.Polymer.2017.11.056  0.724
2018 Poozesh S, Setiawan N, Akafuah NK, Saito K, Marsac PJ. Assessment of predictive models for characterizing the atomization process in a spray dryer’s bi-fluid nozzle Chemical Engineering Science. 180: 42-51. DOI: 10.1016/J.Ces.2018.01.033  0.769
2017 Mugheirbi NA, Marsac PJ, Taylor LS. Insights into Water Induced Phase Separation in Itraconazole-hydroxypropylmethyl cellulose Spin Coated and Spray Dried Dispersions. Molecular Pharmaceutics. PMID 29053281 DOI: 10.1021/Acs.Molpharmaceut.7B00499  0.562
2017 Correa-Soto C, Trasi NS, Schmitt PD, Su Y, Liu Z, Miller E, Variankaval N, Marsac PJ, Simpson GJ, Taylor LS. Second harmonic generation microscopy as a tool for the early detection of crystallization in spray dried dispersions. Journal of Pharmaceutical and Biomedical Analysis. 146: 86-95. PMID 28866472 DOI: 10.1016/J.Jpba.2017.07.066  0.472
2017 Poozesh S, Setiawan N, Arce F, Sundararajan P, Rocca JD, Rumondor A, Wei D, Wenslow R, Xi H, Zhang S, Stellabott J, Su Y, Moser J, Marsac PJ. Understanding the process-product-performance interplay of spray dried drug-polymer systems through complete structural and chemical characterization of single spray dried particles Powder Technology. 320: 685-695. DOI: 10.1016/J.Powtec.2017.07.042  0.682
2016 Nie H, Xu W, Taylor LS, Marsac PJ, Byrn SR. Crystalline solid dispersion-a strategy to slowdown salt disproportionation in solid state formulations during storage and wet granulation. International Journal of Pharmaceutics. PMID 27979765 DOI: 10.1016/J.Ijpharm.2016.12.014  0.56
2016 Nie H, Su Y, Zhang M, Song Y, Leone A, Taylor LS, Marsac PJ, Li T, Byrn SR. Solid-State Spectroscopic Investigation of Molecular Interactions between Clofazimine and Hypromellose Phthalate in Amorphous Solid Dispersions. Molecular Pharmaceutics. PMID 27653759 DOI: 10.1021/Acs.Molpharmaceut.6B00740  0.582
2016 Nie H, Xu W, Ren J, Taylor LS, Marsac PJ, John CT, Byrn SR. Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. Molecular Pharmaceutics. PMID 27542728 DOI: 10.1021/Acs.Molpharmaceut.6B00630  0.436
2016 Mitra A, Li L, Marsac P, Marks B, Liu Z, Brown C. IMPACT OF POLYMER TYPE ON BIOPERFORMANCE AND PHYSICAL STABILITY OF HOT MELT EXTRUDED FORMULATIONS OF A POORLY WATER SOLUBLE DRUG. International Journal of Pharmaceutics. PMID 27012984 DOI: 10.1016/j.ijpharm.2016.03.036  0.441
2015 Nie H, Liu Z, Marks BC, Taylor LS, Byrn SR, Marsac PJ. Analytical approaches to investigate salt disproportionation in tablet matrices by Raman spectroscopy and Raman mapping. Journal of Pharmaceutical and Biomedical Analysis. 118: 328-337. PMID 26590700 DOI: 10.1016/J.Jpba.2015.10.024  0.519
2015 Ilevbare G, Marsac P, Mitra A. Performance and characterization of amorphous solid dispersions: An overview Discovering and Developing Molecules With Optimal Drug-Like Properties. 287-343. DOI: 10.1007/978-1-4939-1399-2_10  0.778
2012 Toth SJ, Madden JT, Taylor LS, Marsac P, Simpson GJ. Selective imaging of active pharmaceutical ingredients in powdered blends with common excipients utilizing two-photon excited ultraviolet-fluorescence and ultraviolet-second order nonlinear optical imaging of chiral crystals. Analytical Chemistry. 84: 5869-75. PMID 22816778 DOI: 10.1021/Ac300917T  0.48
2010 Marsac PJ, Rumondor AC, Nivens DE, Kestur US, Stanciu L, Taylor LS. Effect of temperature and moisture on the miscibility of amorphous dispersions of felodipine and poly(vinyl pyrrolidone). Journal of Pharmaceutical Sciences. 99: 169-85. PMID 19492305 DOI: 10.1002/Jps.21809  0.811
2010 Rumondor ACF, Konno H, Marsac PJ, Taylor LS. Analysis of the moisture sorption behavior of amorphous drug-polymer blends Journal of Applied Polymer Science. 117: 1055-1063. DOI: 10.1002/App.31803  0.644
2009 Rumondor AC, Marsac PJ, Stanford LA, Taylor LS. Phase behavior of poly(vinylpyrrolidone) containing amorphous solid dispersions in the presence of moisture. Molecular Pharmaceutics. 6: 1492-505. PMID 19634917 DOI: 10.1021/Mp900050C  0.822
2009 Marsac PJ, Li T, Taylor LS. Estimation of drug-polymer miscibility and solubility in amorphous solid dispersions using experimentally determined interaction parameters. Pharmaceutical Research. 26: 139-51. PMID 18779927 DOI: 10.1007/S11095-008-9721-1  0.67
2008 Marsac PJ, Romary DP, Shamblin SL, Baird JA, Taylor LS. Spontaneous crystallinity loss of drugs in the disordered regions of poly(ethylene oxide) in the presence of water. Journal of Pharmaceutical Sciences. 97: 3182-94. PMID 18000812 DOI: 10.1002/Jps.21237  0.794
2008 Marsac PJ, Konno H, Rumondor AC, Taylor LS. Recrystallization of nifedipine and felodipine from amorphous molecular level solid dispersions containing poly(vinylpyrrolidone) and sorbed water. Pharmaceutical Research. 25: 647-56. PMID 17846870 DOI: 10.1007/S11095-007-9420-3  0.783
2006 Marsac PJ, Shamblin SL, Taylor LS. Theoretical and practical approaches for prediction of drug-polymer miscibility and solubility. Pharmaceutical Research. 23: 2417-26. PMID 16933098 DOI: 10.1007/S11095-006-9063-9  0.641
2006 Marsac PJ, Konno H, Taylor LS. A comparison of the physical stability of amorphous felodipine and nifedipine systems. Pharmaceutical Research. 23: 2306-16. PMID 16927182 DOI: 10.1007/S11095-006-9047-9  0.472
2005 Wikström H, Marsac PJ, Taylor LS. In-line monitoring of hydrate formation during wet granulation using Raman spectroscopy. Journal of Pharmaceutical Sciences. 94: 209-19. PMID 15761944 DOI: 10.1002/Jps.20241  0.718
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