Year |
Citation |
Score |
2020 |
Ruddle NH. Basics of Inducible Lymphoid Organs. Current Topics in Microbiology and Immunology. PMID 32588229 DOI: 10.1007/82_2020_218 |
0.485 |
|
2020 |
Truman LA, Bentley KL, Ruddle NH. Lymphotoxin targeted to salivary and lacrimal glands induces tertiary lymphoid organs and cervical lymphadenopathy and reduces tear production. European Journal of Immunology. PMID 32012252 DOI: 10.1002/Eji.201948300 |
0.394 |
|
2019 |
Camell CD, Günther P, Lee A, Goldberg EL, Spadaro O, Youm YH, Bartke A, Hubbard GB, Ikeno Y, Ruddle NH, Schultze J, Dixit VD. Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis. Cell Metabolism. PMID 31735593 DOI: 10.1016/J.Cmet.2019.10.006 |
0.346 |
|
2016 |
Ruddle NH. High Endothelial Venules and Lymphatic Vessels in Tertiary Lymphoid Organs: Characteristics, Functions, and Regulation. Frontiers in Immunology. 7: 491. PMID 27881983 DOI: 10.3389/Fimmu.2016.00491 |
0.471 |
|
2016 |
Chia JJ, Zhu T, Chyou S, Dasoveanu DC, Carballo C, Tian S, Magro CM, Rodeo S, Spiera RF, Ruddle NH, McGraw TE, Browning JL, Lafyatis R, Gordon JK, Lu TT. Dendritic cells maintain dermal adipose-derived stromal cells in skin fibrosis. The Journal of Clinical Investigation. PMID 27721238 DOI: 10.1172/Jci85740 |
0.303 |
|
2015 |
Seleznik G, Seeger H, Bauer J, Fu K, Czerkowicz J, Papandile A, Poreci U, Rabah D, Ranger A, Cohen CD, Lindenmeyer M, Chen J, Edenhofer I, Anders HJ, Lech M, ... ... Ruddle NH, et al. The lymphotoxin β receptor is a potential therapeutic target in renal inflammation. Kidney International. PMID 26398497 DOI: 10.1038/Ki.2015.280 |
0.325 |
|
2015 |
Kumar V, Dasoveanu DC, Chyou S, Tzeng TC, Rozo C, Liang Y, Stohl W, Fu YX, Ruddle NH, Lu TT. A dendritic-cell-stromal axis maintains immune responses in lymph nodes. Immunity. 42: 719-30. PMID 25902483 DOI: 10.1016/J.Immuni.2015.03.015 |
0.422 |
|
2014 |
Ruddle NH. Lymphotoxin and TNF: how it all began-a tribute to the travelers. Cytokine & Growth Factor Reviews. 25: 83-9. PMID 24636534 DOI: 10.1016/J.Cytogfr.2014.02.001 |
0.302 |
|
2014 |
Ruddle NH. Lymphatic vessels and tertiary lymphoid organs. The Journal of Clinical Investigation. 124: 953-9. PMID 24590281 DOI: 10.1172/Jci71611 |
0.395 |
|
2014 |
Viehmann Milam AA, Maher SE, Gibson JA, Lebastchi J, Wen L, Ruddle NH, Herold KC, Bothwell AL. A humanized mouse model of autoimmune insulitis. Diabetes. 63: 1712-24. PMID 24478396 DOI: 10.2337/Db13-1141 |
0.352 |
|
2014 |
Paul D, Ge S, Lemire Y, Jellison ER, Serwanski DR, Ruddle NH, Pachter JS. Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation. Journal of Neuroinflammation. 11: 10. PMID 24444311 DOI: 10.1186/1742-2094-11-10 |
0.433 |
|
2014 |
De Togni P, Goellner J, Ruddle NH, Streeter PR, Fick A, Mariathasan S, Smith SC, Carlson R, Shornick LP, Strauss-Schoenberger J, Russell JH, Karr R, Chaplint DD. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin Journal of Immunology. 192: 2007-2014. DOI: 10.1126/science.8171322 |
0.324 |
|
2013 |
Mionnet C, Mondor I, Jorquera A, Loosveld M, Maurizio J, Arcangeli ML, Ruddle NH, Nowak J, Aurrand-Lions M, Luche H, Bajénoff M. Identification of a new stromal cell type involved in the regulation of inflamed B cell follicles. Plos Biology. 11: e1001672. PMID 24130458 DOI: 10.1371/Journal.Pbio.1001672 |
0.431 |
|
2013 |
Truman LA, A-Gonzalez N, Bentley KL, Ruddle NH. Lymphatic vessel function in head and neck inflammation. Lymphatic Research and Biology. 11: 187-92. PMID 24044758 DOI: 10.1089/Lrb.2013.0013 |
0.32 |
|
2013 |
Mionnet C, Mondor I, Jorquera A, Loosveld M, Maurizio J, Arcangeli M, Ruddle NH, Nowak J, Aurrand-Lions M, Luche H, Bajénoff M. CXCR5-deficient B cells fail to access inflamed B cell follicles. Plos Biology. DOI: 10.1371/Journal.Pbio.1001672.G007 |
0.355 |
|
2012 |
Stranford S, Ruddle NH. Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma. Frontiers in Immunology. 3: 350. PMID 23230435 DOI: 10.3389/Fimmu.2012.00350 |
0.461 |
|
2012 |
Kuerten S, Schickel A, Kerkloh C, Recks MS, Addicks K, Ruddle NH, Lehmann PV. Tertiary lymphoid organ development coincides with determinant spreading of the myelin-specific T cell response. Acta Neuropathologica. 124: 861-73. PMID 22842876 DOI: 10.1007/S00401-012-1023-3 |
0.438 |
|
2012 |
Bergman CM, Marta CB, Maric M, Pfeiffer SE, Cresswell P, Ruddle NH. A switch in pathogenic mechanism in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in IFN-γ-inducible lysosomal thiol reductase-free mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 6001-9. PMID 22586035 DOI: 10.4049/Jimmunol.1101898 |
0.415 |
|
2012 |
Truman LA, Bentley KL, Smith EC, Massaro SA, Gonzalez DG, Haberman AM, Hill M, Jones D, Min W, Krause DS, Ruddle NH. ProxTom lymphatic vessel reporter mice reveal Prox1 expression in the adrenal medulla, megakaryocytes, and platelets. The American Journal of Pathology. 180: 1715-25. PMID 22310467 DOI: 10.1016/J.Ajpath.2011.12.026 |
0.381 |
|
2012 |
Motallebzadeh R, Rehakova S, Conlon TM, Win TS, Callaghan CJ, Goddard M, Bolton EM, Ruddle NH, Bradley JA, Pettigrew GJ. Blocking lymphotoxin signaling abrogates the development of ectopic lymphoid tissue within cardiac allografts and inhibits effector antibody responses. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 51-62. PMID 21926237 DOI: 10.1096/Fj.11-186973 |
0.324 |
|
2011 |
Liao S, Cheng G, Conner DA, Huang Y, Kucherlapati RS, Munn LL, Ruddle NH, Jain RK, Fukumura D, Padera TP. Impaired lymphatic contraction associated with immunosuppression. Proceedings of the National Academy of Sciences of the United States of America. 108: 18784-9. PMID 22065738 DOI: 10.1073/Pnas.1116152108 |
0.616 |
|
2011 |
Akirav EM, Xu Y, Ruddle NH. Resident B cells regulate thymic expression of myelin oligodendrocyte glycoprotein. Journal of Neuroimmunology. 235: 33-9. PMID 21550671 DOI: 10.1016/J.Jneuroim.2011.03.013 |
0.76 |
|
2011 |
Bentley KL, Stranford S, Liao S, Mounzer RM, Ruddle FH, Ruddle NH. High endothelial venule reporter mice to probe regulation of lymph node vasculature. Advances in Experimental Medicine and Biology. 691: 35-44. PMID 21153307 DOI: 10.1007/978-1-4419-6612-4_4 |
0.589 |
|
2011 |
Ruddle NH. Workshop summary: roles of the TNF family in normal development and cancer. Advances in Experimental Medicine and Biology. 691: 3-4. PMID 21153304 DOI: 10.1007/978-1-4419-6612-4_1 |
0.307 |
|
2011 |
Akirav EM, Ruddle NH, Herold KC. The role of AIRE in human autoimmune disease. Nature Reviews. Endocrinology. 7: 25-33. PMID 21102544 DOI: 10.1038/Nrendo.2010.200 |
0.744 |
|
2010 |
Bentley KL, Shashikant CS, Wang W, Ruddle NH, Ruddle FH. A yeast-based recombinogenic targeting toolset for transgenic analysis of human disease genes. Annals of the New York Academy of Sciences. 1207: E58-68. PMID 20961307 DOI: 10.1111/J.1749-6632.2010.05712.X |
0.361 |
|
2010 |
Sasaki M, Lankford KL, Brown RJ, Ruddle NH, Kocsis JD. Focal experimental autoimmune encephalomyelitis in the Lewis rat induced by immunization with myelin oligodendrocyte glycoprotein and intraspinal injection of vascular endothelial growth factor. Glia. 58: 1523-31. PMID 20645414 DOI: 10.1002/Glia.21026 |
0.373 |
|
2010 |
Mounzer RH, Svendsen OS, Baluk P, Bergman CM, Padera TP, Wiig H, Jain RK, McDonald DM, Ruddle NH. Lymphotoxin-alpha contributes to lymphangiogenesis. Blood. 116: 2173-82. PMID 20566898 DOI: 10.1182/Blood-2009-12-256065 |
0.459 |
|
2010 |
Penaranda C, Tang Q, Ruddle NH, Bluestone JA. Prevention of diabetes by FTY720-mediated stabilization of peri-islet tertiary lymphoid organs. Diabetes. 59: 1461-8. PMID 20299465 DOI: 10.2337/Db09-1129 |
0.325 |
|
2010 |
Ruddle NH, Truman LA, KLB. SS9-6 In vivo imaging of high endothelial venules and lymphatic vessels in lymph nodes and tertiary lymphoid organs Cytokine. 52: 77-77. DOI: 10.1016/J.Cyto.2010.07.320 |
0.319 |
|
2009 |
Ruddle NH, Akirav EM. Secondary lymphoid organs: responding to genetic and environmental cues in ontogeny and the immune response. Journal of Immunology (Baltimore, Md. : 1950). 183: 2205-12. PMID 19661265 DOI: 10.4049/Jimmunol.0804324 |
0.753 |
|
2009 |
Akirav EM, Bergman CM, Hill M, Ruddle NH. Depletion of CD4(+)CD25(+) T cells exacerbates experimental autoimmune encephalomyelitis induced by mouse, but not rat, antigens. Journal of Neuroscience Research. 87: 3511-9. PMID 19125411 DOI: 10.1002/Jnr.21981 |
0.754 |
|
2009 |
Ruddle NH. Lymphotoxin: From inflammation to lymphoid organs and back Cytokine. 48: 113. DOI: 10.1016/J.Cyto.2009.07.477 |
0.329 |
|
2007 |
Liao S, Bentley K, Lebrun M, Lesslauer W, Ruddle FH, Ruddle NH. Transgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules. Proceedings of the National Academy of Sciences of the United States of America. 104: 4577-82. PMID 17360566 DOI: 10.1073/Pnas.0700334104 |
0.618 |
|
2007 |
Nasr IW, Reel M, Oberbarnscheidt MH, Mounzer RH, Baddoura FK, Ruddle NH, Lakkis FG. Tertiary lymphoid tissues generate effector and memory T cells that lead to allograft rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7: 1071-9. PMID 17359505 DOI: 10.1111/J.1600-6143.2007.01756.X |
0.408 |
|
2006 |
Marinkovic T, Garin A, Yokota Y, Fu YX, Ruddle NH, Furtado GC, Lira SA. Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid. The Journal of Clinical Investigation. 116: 2622-32. PMID 16998590 DOI: 10.1172/Jci28993 |
0.341 |
|
2006 |
Liao S, Ruddle NH. Synchrony of high endothelial venules and lymphatic vessels revealed by immunization. Journal of Immunology (Baltimore, Md. : 1950). 177: 3369-79. PMID 16920978 DOI: 10.4049/Jimmunol.177.5.3369 |
0.615 |
|
2006 |
Drayton DL, Liao S, Mounzer RH, Ruddle NH. Lymphoid organ development: from ontogeny to neogenesis. Nature Immunology. 7: 344-53. PMID 16550197 DOI: 10.1038/Ni1330 |
0.746 |
|
2005 |
Marta CB, Oliver AR, Sweet RA, Pfeiffer SE, Ruddle NH. Pathogenic myelin oligodendrocyte glycoprotein antibodies recognize glycosylated epitopes and perturb oligodendrocyte physiology. Proceedings of the National Academy of Sciences of the United States of America. 102: 13992-7. PMID 16172404 DOI: 10.1073/Pnas.0504979102 |
0.399 |
|
2005 |
Baddoura FK, Nasr IW, Wrobel B, Li Q, Ruddle NH, Lakkis FG. Lymphoid neogenesis in murine cardiac allografts undergoing chronic rejection. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 510-6. PMID 15707405 DOI: 10.1111/J.1600-6143.2004.00714.X |
0.412 |
|
2005 |
Heikenwalder M, Zeller N, Seeger H, Prinz M, Klöhn PC, Schwarz P, Ruddle NH, Weissmann C, Aguzzi A. Chronic lymphocytic inflammation specifies the organ tropism of prions. Science (New York, N.Y.). 307: 1107-10. PMID 15661974 DOI: 10.1126/Science.1106460 |
0.442 |
|
2005 |
Ying X, Chan K, Shenoy P, Hill M, Ruddle NH. Lymphotoxin plays a crucial role in the development and function of nasal-associated lymphoid tissue through regulation of chemokines and peripheral node addressin. The American Journal of Pathology. 166: 135-46. PMID 15632007 DOI: 10.1016/S0002-9440(10)62239-0 |
0.435 |
|
2004 |
Drayton DL, Bonizzi G, Ying X, Liao S, Karin M, Ruddle NH. I kappa B kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue. Journal of Immunology (Baltimore, Md. : 1950). 173: 6161-8. PMID 15528353 DOI: 10.4049/Jimmunol.173.10.6161 |
0.768 |
|
2004 |
Soderberg KA, Linehan MM, Ruddle NH, Iwasaki A. MAdCAM-1 expressing sacral lymph node in the lymphotoxin beta-deficient mouse provides a site for immune generation following vaginal herpes simplex virus-2 infection. Journal of Immunology (Baltimore, Md. : 1950). 173: 1908-13. PMID 15265924 DOI: 10.4049/Jimmunol.173.3.1908 |
0.377 |
|
2004 |
Bistrup A, Tsay D, Shenoy P, Singer MS, Bangia N, Luther SA, Cyster JG, Ruddle NH, Rosen SD. Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope. The American Journal of Pathology. 164: 1635-44. PMID 15111310 DOI: 10.1016/S0002-9440(10)63722-4 |
0.399 |
|
2003 |
Oliver AR, Lyon GM, Ruddle NH. Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 462-8. PMID 12817031 DOI: 10.4049/Jimmunol.171.1.462 |
0.412 |
|
2003 |
Shomer NH, Fox JG, Juedes AE, Ruddle NH. Helicobacter-induced chronic active lymphoid aggregates have characteristics of tertiary lymphoid tissue. Infection and Immunity. 71: 3572-7. PMID 12761142 DOI: 10.1128/Iai.71.6.3572-3577.2003 |
0.767 |
|
2003 |
Drayton DL, Ying X, Lee J, Lesslauer W, Ruddle NH. Ectopic LT alpha beta directs lymphoid organ neogenesis with concomitant expression of peripheral node addressin and a HEV-restricted sulfotransferase. The Journal of Experimental Medicine. 197: 1153-63. PMID 12732657 DOI: 10.1084/Jem.20021761 |
0.762 |
|
2002 |
Constant SL, Brogdon JL, Piggott DA, Herrick CA, Visintin I, Ruddle NH, Bottomly K. Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ. The Journal of Clinical Investigation. 110: 1441-8. PMID 12438442 DOI: 10.1172/Jci16109 |
0.404 |
|
2002 |
Drayton DL, Chan K, Lesslauer W, Lee J, Ying XY, Ruddle NH. Lymphocyte traffic in lymphoid organ neogenesis: differential roles of Ltalpha and LTalphabeta. Advances in Experimental Medicine and Biology. 512: 43-8. PMID 12405186 |
0.767 |
|
2002 |
Suresh M, Lanier G, Large MK, Whitmire JK, Altman JD, Ruddle NH, Ahmed R. Role of lymphotoxin alpha in T-cell responses during an acute viral infection. Journal of Virology. 76: 3943-51. PMID 11907234 DOI: 10.1128/Jvi.76.8.3943-3951.2002 |
0.459 |
|
2002 |
Graesser D, Solowiej A, Bruckner M, Osterweil E, Juedes A, Davis S, Ruddle NH, Engelhardt B, Madri JA. Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. The Journal of Clinical Investigation. 109: 383-92. PMID 11827998 DOI: 10.1172/Jci13595 |
0.775 |
|
2002 |
Ruddle NH. Geertruida Jeanette Thorbecke (1929–2001) Immunity. 16: 329-330. DOI: 10.1016/S1074-7613(02)00292-3 |
0.391 |
|
2001 |
Hemmerich S, Bistrup A, Singer MS, van Zante A, Lee JK, Tsay D, Peters M, Carminati JL, Brennan TJ, Carver-Moore K, Leviten M, Fuentes ME, Ruddle NH, Rosen SD. Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes. Immunity. 15: 237-47. PMID 11520459 DOI: 10.1016/S1074-7613(01)00188-1 |
0.341 |
|
2001 |
Dong C, Juedes AE, Temann UA, Shresta S, Allison JP, Ruddle NH, Flavell RA. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature. 409: 97-101. PMID 11343121 DOI: 10.1038/35051100 |
0.782 |
|
2001 |
Spahn TW, Fontana A, Faria AM, Slavin AJ, Eugster HP, Zhang X, Koni PA, Ruddle NH, Flavell RA, Rennert PD, Weiner HL. Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches. European Journal of Immunology. 31: 1278-87. PMID 11298355 DOI: 10.1002/1521-4141(200104)31:4<1278::Aid-Immu1278>3.0.Co;2-A |
0.384 |
|
2001 |
Juedes AE, Ruddle NH. Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 166: 5168-75. PMID 11290800 DOI: 10.4049/Jimmunol.166.8.5168 |
0.783 |
|
2001 |
Goluszko E, Hjelmström P, Deng C, Poussin MA, Ruddle NH, Christadoss P. Lymphotoxin-alpha deficiency completely protects C57BL/6 mice from developing clinical experimental autoimmune myasthenia gravis. Journal of Neuroimmunology. 113: 109-18. PMID 11137582 DOI: 10.1016/S0165-5728(00)00420-3 |
0.382 |
|
2000 |
Hjelmström P, Fjell J, Nakagawa T, Sacca R, Cuff CA, Ruddle NH. Lymphoid tissue homing chemokines are expressed in chronic inflammation. The American Journal of Pathology. 156: 1133-8. PMID 10751336 DOI: 10.1016/S0002-9440(10)64981-4 |
0.454 |
|
2000 |
Juedes AE, Hjelmström P, Bergman CM, Neild AL, Ruddle NH. Kinetics and cellular origin of cytokines in the central nervous system: insight into mechanisms of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 164: 419-26. PMID 10605038 DOI: 10.4049/Jimmunol.164.1.419 |
0.768 |
|
1999 |
Li C, Horowitz MC, Ruddle NH. Murine neurofibroma reversion by antisense RNA for HTLV-I tax. Science in China. Series C, Life Sciences / Chinese Academy of Sciences. 42: 8-16. PMID 18726492 DOI: 10.1007/Bf02881742 |
0.362 |
|
1999 |
Ruddle NH. Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development. Immunologic Research. 19: 119-25. PMID 10493167 DOI: 10.1007/Bf02786481 |
0.456 |
|
1999 |
Cuff CA, Sacca R, Ruddle NH. Differential induction of adhesion molecule and chemokine expression by LTalpha3 and LTalphabeta in inflammation elucidates potential mechanisms of mesenteric and peripheral lymph node development. Journal of Immunology (Baltimore, Md. : 1950). 162: 5965-72. PMID 10229834 |
0.326 |
|
1998 |
Hjelmström P, Juedes AE, Ruddle NH. Cytokines and antibodies in myelin oligodendrocyte glycoprotein-induced experimental allergic encephalomyelitis. Research in Immunology. 149: 794-804; discussion . PMID 9923635 DOI: 10.1016/S0923-2494(99)80007-8 |
0.723 |
|
1998 |
Martin R, Ruddle NH, Reingold S, Hafler DA. T helper cell differentiation in multiple sclerosis and autoimmunity. Immunology Today. 19: 495-8. PMID 9818541 DOI: 10.1016/S0167-5699(98)01345-0 |
0.376 |
|
1998 |
Hjelmström P, Juedes AE, Fjell J, Ruddle NH. B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization. Journal of Immunology (Baltimore, Md. : 1950). 161: 4480-3. PMID 9794370 |
0.765 |
|
1998 |
Cuff CA, Schwartz J, Sacca R, Bergman CM, Russel K, Bender J, Ruddle NH. Lymphotoxin regulates the trafficking of T lymphocytes of the memory and naive phenotype Faseb Journal. 12: A1054. |
0.36 |
|
1997 |
Sacca R, Cuff CA, Ruddle NH. Mediators of inflammation. Current Opinion in Immunology. 9: 851-7. PMID 9492989 DOI: 10.1016/S0952-7915(97)80189-6 |
0.347 |
|
1997 |
Sacca R, Turley S, Soong L, Mellman I, Ruddle NH. Transgenic Expression of Lymphotoxin Restores Lymph Nodes to Lymphotoxin-α-Deficient Mice Journal of Immunology. 159: 4252-4260. PMID 9379020 |
0.303 |
|
1997 |
Suen WE, Bergman CM, Hjelmström P, Ruddle NH. A critical role for lymphotoxin in experimental allergic encephalomyelitis. The Journal of Experimental Medicine. 186: 1233-40. PMID 9334362 DOI: 10.1084/Jem.186.8.1233 |
0.417 |
|
1997 |
Soong L, Chang CH, Sun J, Longley BJ, Ruddle NH, Flavell RA, McMahon-Pratt D. Role of CD4+ T cells in pathogenesis associated with Leishmania amazonensis infection. Journal of Immunology (Baltimore, Md. : 1950). 158: 5374-83. PMID 9164958 |
0.304 |
|
1997 |
Koni PA, Sacca R, Lawton P, Browning JL, Ruddle NH, Flavell RA. Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient mice. Immunity. 6: 491-500. PMID 9133428 DOI: 10.1016/S1074-7613(00)80292-7 |
0.382 |
|
1997 |
Ferreri NR, Millet I, Askari B, Magnani P, Ruddle NH. Lymphotoxin-beta and TNF regulation in T cell subsets: differential effects of PGE2. Cytokine. 9: 157-65. PMID 9126704 DOI: 10.1006/Cyto.1996.0150 |
0.4 |
|
1996 |
Kima PE, Soong L, Chicharro C, Ruddle NH, McMahon-Pratt D. Leishmania-infected macrophages sequester endogenously synthesized parasite antigens from presentation to CD4+ T cells. European Journal of Immunology. 26: 3163-9. PMID 8977318 DOI: 10.1002/Eji.1830261249 |
0.379 |
|
1996 |
Kratz A, Campos-Neto A, Hanson MS, Ruddle NH. Chronic inflammation caused by lymphotoxin is lymphoid neogenesis. The Journal of Experimental Medicine. 183: 1461-72. PMID 8666904 DOI: 10.1084/Jem.183.4.1461 |
0.535 |
|
1996 |
Soong L, Xu JC, Grewal IS, Kima P, Sun J, Longley BJ, Ruddle NH, McMahon-Pratt D, Flavell RA. Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity. 4: 263-73. PMID 8624816 DOI: 10.1016/S1074-7613(00)80434-3 |
0.382 |
|
1996 |
Flavell RA, Kratz A, Ruddle NH. The contribution of insulitis to diabetes development in tumor necrosis factor transgenic mice. Current Topics in Microbiology and Immunology. 206: 33-50. PMID 8608724 DOI: 10.1007/978-3-642-85208-4_3 |
0.411 |
|
1995 |
Campos-Neto A, Soong L, Cordova JL, Sant'Angelo D, Skeiky YAW, Ruddle NH, Reed SG, Janeway C, McMahon-Pratt D. Cloning and expression of a Leishmania donovani gene instructed by a peptide isolated from major histocompatibility complex class II molecules of infected macrophages Journal of Experimental Medicine. 182: 1423-1433. PMID 7595213 DOI: 10.1084/Jem.182.5.1423 |
0.339 |
|
1994 |
De Togni P, Goellner J, Ruddle NH, Streeter PR, Fick A, Mariathasan S, Smith SC, Carlson R, Shornick LP, Strauss-Schoenberger J. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science (New York, N.Y.). 264: 703-7. PMID 8171322 DOI: 10.1126/Science.8171322 |
0.433 |
|
1994 |
Barten DM, Ruddle NH. Vascular cell adhesion molecule-1 modulation by tumor necrosis factor in experimental allergic encephalomyelitis. Journal of Neuroimmunology. 51: 123-33. PMID 7514184 DOI: 10.1016/0165-5728(94)90074-4 |
0.403 |
|
1993 |
McMahon-Pratt D, Rodriguez D, Rodriguez JR, Zhang Y, Manson K, Bergman C, Rivas L, Rodriguez JF, Lohman KL, Ruddle NH. Recombinant vaccinia viruses expressing GP46/M-2 protect against Leishmania infection. Infection and Immunity. 61: 3351-9. PMID 8335366 DOI: 10.1128/Iai.61.8.3351-3359.1993 |
0.349 |
|
1993 |
Ruddle NH, Picarella D, Kratz A, Li CB, Flavell RA. Probing the mechanism of TNF-alpha(cachectin)- and TNF-beta(lymphotoxin)-induced pancreatic inflammation with transgenic mice. Research in Immunology. 144: 336-42. PMID 8278655 DOI: 10.1016/S0923-2494(93)80077-C |
0.355 |
|
1993 |
Ruddle NH, Li CB, Horne WC, Santiago P, Troiano N, Jay G, Horowitz M, Baron R. Mice transgenic for HTLV-I LTR-tax exhibit tax expression in bone, skeletal alterations, and high bone turnover Virology. 197: 196-204. PMID 8212554 DOI: 10.1006/Viro.1993.1580 |
0.301 |
|
1993 |
Voskuhl RR, Martin R, Bergman C, Dalal M, Ruddle NH, McFarland HF. T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes. Autoimmunity. 15: 137-43. PMID 7692995 DOI: 10.3109/08916939309043888 |
0.422 |
|
1993 |
Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway CA. Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma Journal of Experimental Medicine. 177: 57-68. PMID 7678116 DOI: 10.1084/Jem.177.1.57 |
0.453 |
|
1993 |
Paul NL, Millet I, Ruddle NH. The lymphotoxin promoter is stimulated by HTLV-I tax activation of NF-kappa B in human T-cell lines. Cytokine. 5: 372-8. PMID 7505113 DOI: 10.1016/1043-4666(93)90070-L |
0.372 |
|
1992 |
Ruddle NH. Tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta). Current Opinion in Immunology. 4: 327-32. PMID 1329840 DOI: 10.1016/0952-7915(92)90084-R |
0.316 |
|
1992 |
Picarella DE, Kratz A, Li CB, Ruddle NH, Flavell RA. Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas. Proceedings of the National Academy of Sciences of the United States of America. 89: 10036-40. PMID 1279667 DOI: 10.1073/Pnas.89.21.10036 |
0.395 |
|
1990 |
Ruddle NH, Bergman CM, McGrath KM, Lingenheld EG, Grunnet ML, Padula SJ, Clark RB. An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. The Journal of Experimental Medicine. 172: 1193-200. PMID 2212948 DOI: 10.1084/Jem.172.4.1193 |
0.419 |
|
1990 |
Paul NL, Lenardo MJ, Novak KD, Sarr T, Tang WL, Ruddle NH. Lymphotoxin activation by human T-cell leukemia virus type I-infected cell lines: role for NF-kappa B. Journal of Virology. 64: 5412-9. PMID 1976820 DOI: 10.1128/Jvi.64.11.5412-5419.1990 |
0.393 |
|
1990 |
Powell MB, Mitchell D, Lederman J, Buckmeier J, Zamvil SS, Graham M, Ruddle NH, Steinman L. Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. International Immunology. 2: 539-44. PMID 1707660 DOI: 10.1093/Intimm/2.6.539 |
0.383 |
|
1988 |
Paul NL, Ruddle NH. Lymphotoxin. Annual Review of Immunology. 6: 407-38. PMID 3289572 DOI: 10.1146/annurev.iy.06.040188.002203 |
0.32 |
|
1987 |
Shiohara T, Ruddle NH, Horowitz M, Moellmann GE, Lerner AB. Anti-tumor activity of class II MHC antigen-restricted cloned autoreactive T cells. I. Destruction of B16 melanoma cells mediated by bystander cytolysis in vitro Journal of Immunology. 138: 1971-1978. PMID 3102609 |
0.343 |
|
1987 |
Mate TP, Ruddle NH. Suppressor cells induced by total lymphoid irradiation affect proliferation and lymphokine production of murine T helper cell clones. International Journal of Radiation Oncology, Biology, Physics. 13: 61-8. PMID 2948938 DOI: 10.1016/0360-3016(87)90261-6 |
0.457 |
|
1986 |
Ruddle NH. Lymphotoxin production in AIDS. Immunology Today. 7: 8-9. PMID 25291416 DOI: 10.1016/0167-5699(86)90181-7 |
0.378 |
|
1986 |
Cone RE, Beaman KD, Ruddle N. Isolation of antigen-binding membrane molecules from an antigen-specific T-cell hybrid. Cellular Immunology. 99: 257-64. PMID 3489563 DOI: 10.1016/0008-8749(86)90233-9 |
0.349 |
|
1985 |
Ruddle NH. Lymphotoxin redux. Immunology Today. 6: 156-9. PMID 25289782 DOI: 10.1016/0167-5699(85)90144-6 |
0.313 |
|
1985 |
Schmid DS, Powell MB, Mahoney KA, Ruddle NH. A comparison of lysis mediated by Lyt 2+ TNP-specific cytotoxic-T-lymphocyte (CTL) lines with that mediated by rapidly internalized lymphotoxin-containing supernatant fluids: evidence for a role of soluble mediators in CTL-mediated killing. Cellular Immunology. 93: 68-82. PMID 3873290 DOI: 10.1016/0008-8749(85)90389-2 |
0.421 |
|
1985 |
Broome Powel M, Conta BS, Horowitz M, Ruddle NH. The differential inhibitory effect of lymphotoxin and immune interferon on normal and malignant lymphoid cells Lymphokine Research. 4: 13-26. PMID 2984482 |
0.304 |
|
1985 |
Tite JP, Powell MB, Ruddle NH. Protein-antigen specific Ia-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis. Journal of Immunology (Baltimore, Md. : 1950). 135: 25-33. PMID 2582034 |
0.3 |
|
1985 |
Conta BS, Powell MB, Ruddle NH. Activation of Lyt-1+ and Lyt-2+ T cell cloned lines: stimulation of proliferation, lymphokine production, and self-destruction. Journal of Immunology (Baltimore, Md. : 1950). 134: 2185-90. PMID 2579131 |
0.304 |
|
1984 |
Beaman KD, Ruddle NH, Bothwell AL, Cone RE. Messenger RNA for an antigen-specific binding molecule from an antigen-specific T-cell hybrid Proceedings of the National Academy of Sciences of the United States of America. 81: 1524-1528. PMID 6200878 DOI: 10.1073/Pnas.81.5.1524 |
0.349 |
|
1982 |
Zuniga MC, D'Eustachio P, Ruddle NH. Immunoglobulin heavy chain gene rearrangement and transcription in murine T cell hybrids and T lymphomas Proceedings of the National Academy of Sciences of the United States of America. 79: 3015-3019. PMID 6806823 DOI: 10.1073/Pnas.79.9.3015 |
0.335 |
|
1982 |
Beezley BB, Ruddle NH. A critical analysis of the T cell hybrid technique Journal of Immunological Methods. 52: 269-281. PMID 6752275 DOI: 10.1016/0022-1759(82)90001-1 |
0.362 |
|
1980 |
Ruddle NH, Beezley BB, Eardley DD. Regulation of self-recognition by T-cell hybrids. Cellular Immunology. 55: 42-55. PMID 6968629 DOI: 10.1016/0008-8749(80)90135-5 |
0.44 |
|
1980 |
Goodman JW, Lewis GK, Primi D, Hornbeck P, Ruddle NH. Antigen-specific molecules from murine T lymphocytes and T cell hybridomas Molecular Immunology. 17: 933-945. PMID 6163975 DOI: 10.1016/0161-5890(80)90042-5 |
0.44 |
|
1980 |
Ruddle NH, Beezley B, Lewis GK, Goodman JW. Antigen specific T cell hybrids-II. T cell hybrids which bind azobenzenearsonate Molecular Immunology. 17: 925-931. PMID 6163974 DOI: 10.1016/0161-5890(80)90041-3 |
0.418 |
|
1980 |
Whitaker RB, Ruddle NH. Antigen-specific T-cell hybrids. I. Ovalbumin binding T-cell hybrid Cellular Immunology. 55: 56-65. PMID 6159106 DOI: 10.1016/0008-8749(80)90136-7 |
0.403 |
|
1979 |
Ruddle NH. Delayed hypersensitivity to soluble antigens in mice. II. Analysis in vitro International Archives of Allergy and Applied Immunology. 58: 44-52. PMID 422279 |
0.336 |
|
1977 |
Armstrong MYK, Ruddle NH, Richards FF. Expression of endogenous murine leukemia viruses during the course of a protracted immunological disorder Journal of Experimental Medicine. 145: 1060-1065. PMID 16072 DOI: 10.1084/Jem.145.4.1060 |
0.334 |
|
1977 |
Armstrong MYK, Ruddle NH, Lipman MB, Pierce SK, Richards FF. Role of endogenous murine leukemia virus in immunologically triggered lymphoreticular tumors. I. Development and use of oncogenic cellfree preparations serially passaged in vivo Journal of the National Cancer Institute. 58: 67-72. PMID 13227 DOI: 10.1093/Jnci/58.1.67 |
0.337 |
|
1976 |
Hecht TT, Ruddle NH, Ruddle FH. Separation and analysis of differentiating B lymphocytes from mouse spleens Cellular Immunology. 22: 193-210. PMID 1084225 DOI: 10.1016/0008-8749(76)90023-X |
0.371 |
|
1976 |
Ruddle NH, Armstrong MYK, Richards FF. Replication of murine leukemia virus in bone marrow derived lymphocytes Proceedings of the National Academy of Sciences of the United States of America. 73: 3714-3718. PMID 185625 DOI: 10.1073/Pnas.73.10.3714 |
0.372 |
|
1973 |
Armstrong MY, Ruddle NH, Lipman MB, Richards FF. Tumor induction by immunologically activated murine leukemia virus. The Journal of Experimental Medicine. 137: 1163-79. PMID 4144984 DOI: 10.1084/Jem.137.5.1163 |
0.349 |
|
1972 |
Ruddle NH. Approaches to the quantitative analysis of delayed hypersensitivity Current Topics in Microbiology and Immunology. 57: 75-110. PMID 4554356 DOI: 10.1007/978-3-642-65297-4_3 |
0.354 |
|
1968 |
Ruddle NH, Waksman BH. Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. 3. Analysis of mechanism Journal of Experimental Medicine. 128: 1267-1279. PMID 5693925 DOI: 10.1084/Jem.128.6.1267 |
0.38 |
|
1968 |
Ruddle NH, Waksman BH. Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. II. Correlation of the in vitro response with skin reactivity Journal of Experimental Medicine. 128: 1255-1265. PMID 4235040 DOI: 10.1084/Jem.128.6.1255 |
0.35 |
|
1968 |
Ruddle NH, Waksman BH. Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. I. Characterization of the phenomenon Journal of Experimental Medicine. 128: 1237-1254. PMID 4176937 DOI: 10.1084/Jem.128.6.1237 |
0.395 |
|
1967 |
Ruddle NH, Waksman BH. Cytotoxic effect of lymphocyte-antigen interaction in delayed hypersensitivity Science. 157: 1060-1062. PMID 6036235 DOI: 10.1126/Science.157.3792.1060 |
0.346 |
|
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