| Year |
Citation |
Score |
| 2024 |
Yu H, Chiang A, Rubinstein M, Low MJ. The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice. Molecular Metabolism. 101993. PMID 39025297 DOI: 10.1016/j.molmet.2024.101993 |
0.565 |
|
| 2024 |
Rojo D, Hael CE, Soria A, de Souza FSJ, Low MJ, Franchini LF, Rubinstein M. A mammalian tripartite enhancer cluster controls hypothalamic expression, food intake, and body weight. Proceedings of the National Academy of Sciences of the United States of America. 121: e2322692121. PMID 38652744 DOI: 10.1073/pnas.2322692121 |
0.547 |
|
| 2022 |
Eliason NL, Martin L, Low MJ, Sharpe AL. Melanocortin receptor agonist melanotan-II microinjected in the nucleus accumbens decreases appetitive and consumptive responding for food. Neuropeptides. 96: 102289. PMID 36155088 DOI: 10.1016/j.npep.2022.102289 |
0.774 |
|
| 2022 |
Yu H, Rubinstein M, Low MJ. Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 11. PMID 35044906 DOI: 10.7554/eLife.72883 |
0.508 |
|
| 2021 |
Surbhi, Wittmann G, Low MJ, Lechan RM. Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency. Molecular Metabolism. 101312. PMID 34329773 DOI: 10.1016/j.molmet.2021.101312 |
0.584 |
|
| 2021 |
Shakya M, Gahlot S, White A, Verchere CB, Low MJ, Lindberg I. Mice lacking PC1/3 expression in POMC-expressing cells do not develop obesity. Endocrinology. PMID 33693631 DOI: 10.1210/endocr/bqab055 |
0.319 |
|
| 2020 |
Na ES, Lam DD, Yokosawa E, Adams JM, Olson DP, Low MJ. Decreased sensitivity to the anorectic effects of leptin in mice that lack a Pomc-specific neural enhancer. Plos One. 15: e0244793. PMID 33382813 DOI: 10.1371/journal.pone.0244793 |
0.662 |
|
| 2020 |
Hael CE, Rojo D, Orquera DP, Low MJ, Rubinstein M. The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight. Molecular Metabolism. 34: 43-53. PMID 32180559 DOI: 10.1016/j.molmet.2020.01.007 |
0.525 |
|
| 2020 |
Yu H, Thompson Z, Kiran S, Jones GL, Mundada L, Gahlot S, Rubinstein M, Low MJ. Expression of a hypomorphic Pomc allele alters leptin dynamics during late pregnancy. The Journal of Endocrinology. PMID 32027603 DOI: 10.1530/JOE-19-0576 |
0.518 |
|
| 2020 |
Gahlot S, Wittmann G, Lechan RM, Low MJ. OR16-03 Metabolic Effects Of Hypothalamic Pomc Neurons Generated Postnatally From Tanycytes On A Pomc Null Genetic Background Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.142 |
0.63 |
|
| 2020 |
Yu H, Jones G, Thompson Z, Rubinstein M, Low MJ. MON-709 Single-Cell RNA-Sequencing Deciphers POMC Neuron Destiny Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1333 |
0.501 |
|
| 2019 |
Jones GL, Wittmann G, Yokosawa EB, Yu H, Mercer AJ, Lechan RM, Low MJ. Selective Restoration of Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network. Eneuro. 6. PMID 30957016 DOI: 10.1523/ENEURO.0400-18.2019 |
0.768 |
|
| 2019 |
Orquera DP, Tavella MB, de Souza FSJ, Nasif S, Low MJ, Rubinstein M. The homeodomain transcription factor NKX2.1 is essential for the early specification of melanocortin neuron identity and activates expression in the developing hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30886014 DOI: 10.1523/JNEUROSCI.2924-18.2019 |
0.535 |
|
| 2017 |
Steyn FJ, Ngo ST, Chen VP, Bailey-Downs LC, Xie TY, Ghadami M, Brimijoin S, Freeman WM, Rubinstein M, Low MJ, Stout MB. 17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior. Aging Cell. PMID 29168299 DOI: 10.1111/acel.12703 |
0.457 |
|
| 2017 |
Zhou Y, Rubinstein M, Low M, Kreek MJ. V1b receptor antagonist SSR149415 and naltrexone synergistically decrease excessive alcohol drinking in male and female mice. Alcoholism, Clinical and Experimental Research. PMID 29105118 DOI: 10.1111/Acer.13544 |
0.418 |
|
| 2017 |
Burke LK, Ogunnowo-Bada E, Georgescu T, Cristiano C, de Morentin PBM, Valencia Torres L, D'Agostino G, Riches C, Heeley N, Ruan Y, Rubinstein M, Low MJ, Myers MG, Rochford JJ, Evans ML, et al. Lorcaserin improves glycemic control via a melanocortin neurocircuit. Molecular Metabolism. 6: 1092-1102. PMID 29031711 DOI: 10.1016/J.Molmet.2017.07.004 |
0.647 |
|
| 2017 |
Rubinstein M, Low MJ. Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity. Febs Letters. PMID 28771698 DOI: 10.1002/1873-3468.12776 |
0.491 |
|
| 2016 |
Zhou Y, Rubinstein M, Low MJ, Kreek MJ. Hypothalamic-specific proopiomelanocortin-deficiency reduces alcohol drinking in male and female mice. Genes, Brain, and Behavior. PMID 27870313 DOI: 10.1111/Gbb.12362 |
0.418 |
|
| 2016 |
Chhabra KH, Adams JM, Jones GL, Yamashita M, Schlapschy M, Skerra A, Rubinstein M, Low MJ. Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity. Molecular Metabolism. 5: 869-81. PMID 27689000 DOI: 10.1016/j.molmet.2016.07.012 |
0.473 |
|
| 2016 |
Orquera DP, Nasif S, Low MJ, Rubinstein M, de Souza FS. Essential function of the transcription factor Rax in the early patterning of the mammalian hypothalamus. Developmental Biology. PMID 27212025 DOI: 10.1016/j.ydbio.2016.05.021 |
0.462 |
|
| 2016 |
Burke LK, Doslikova B, D'Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, ... Low MJ, et al. Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons. Molecular Metabolism. 5: 245-52. PMID 26977396 DOI: 10.1016/J.Molmet.2016.01.005 |
0.763 |
|
| 2016 |
Burke LK, Doslikova B, D'Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, ... Low MJ, et al. Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons Molecular Metabolism. 5: 245-252. DOI: 10.1016/j.molmet.2016.01.005 |
0.76 |
|
| 2015 |
Chhabra KH, Adams JM, Fagel B, Lam DD, Qi N, Rubinstein M, Low MJ. Hypothalamic POMC-deficiency improves glucose tolerance despite insulin resistance by increasing glycosuria. Diabetes. PMID 26467632 DOI: 10.2337/Db15-0804 |
0.662 |
|
| 2015 |
Nasif S, de Souza FS, González LE, Yamashita M, Orquera DP, Low MJ, Rubinstein M. Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood. Proceedings of the National Academy of Sciences of the United States of America. 112: E1861-70. PMID 25825735 DOI: 10.1073/pnas.1500672112 |
0.558 |
|
| 2015 |
Lam DD, de Souza FS, Nasif S, Yamashita M, López-Leal R, Otero-Corchon V, Meece K, Sampath H, Mercer AJ, Wardlaw SL, Rubinstein M, Low MJ. Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold. Plos Genetics. 11: e1004935. PMID 25671638 DOI: 10.1371/Journal.Pgen.1004935 |
0.796 |
|
| 2015 |
Lam DD, Attard CA, Mercer AJ, Myers MG, Rubinstein M, Low MJ. Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism. Endocrinology. 156: 1292-302. PMID 25594696 DOI: 10.1210/En.2014-1373 |
0.814 |
|
| 2015 |
Zhou Y, Rubinstein M, Low MJ, Kreek MJ. Alcohol drinking and related behaviors in hypothalamic-specific Pomc-deficient mice Drug and Alcohol Dependence. 146: e31-e32. DOI: 10.1016/J.Drugalcdep.2014.09.766 |
0.431 |
|
| 2014 |
Burke LK, Doslikova B, D'Agostino G, Garfield AS, Farooq G, Burdakov D, Low MJ, Rubinstein M, Evans ML, Billups B, Heisler LK. 5-HT obesity medication efficacy via POMC activation is maintained during aging. Endocrinology. 155: 3732-8. PMID 25051442 DOI: 10.1210/En.2014-1223 |
0.67 |
|
| 2014 |
Mercer AJ, Stuart RC, Attard CA, Otero-Corchon V, Nillni EA, Low MJ. Temporal changes in nutritional state affect hypothalamic POMC peptide levels independently of leptin in adult male mice. American Journal of Physiology. Endocrinology and Metabolism. 306: E904-15. PMID 24518677 DOI: 10.1152/Ajpendo.00540.2013 |
0.675 |
|
| 2013 |
Domené S, Bumaschny VF, de Souza FS, Franchini LF, Nasif S, Low MJ, Rubinstein M. Enhancer turnover and conserved regulatory function in vertebrate evolution. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20130027. PMID 24218639 DOI: 10.1098/Rstb.2013.0027 |
0.501 |
|
| 2013 |
NoaÃn D, Pérez-Millán MI, Bello EP, Luque GM, Casas Cordero R, Gelman DM, Peper M, Tornadu IG, Low MJ, Becú-Villalobos D, Rubinstein M. Central dopamine D2 receptors regulate growth-hormone-dependent body growth and pheromone signaling to conspecific males. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5834-42. PMID 23536095 DOI: 10.1523/Jneurosci.5673-12.2013 |
0.501 |
|
| 2013 |
Mercer AJ, Hentges ST, Meshul CK, Low MJ. Unraveling the central proopiomelanocortin neural circuits. Frontiers in Neuroscience. 7: 19. PMID 23440036 DOI: 10.3389/Fnins.2013.00019 |
0.782 |
|
| 2012 |
Bumaschny VF, Yamashita M, Casas-Cordero R, Otero-Corchón V, de Souza FS, Rubinstein M, Low MJ. Obesity-programmed mice are rescued by early genetic intervention. The Journal of Clinical Investigation. 122: 4203-12. PMID 23093774 DOI: 10.1172/Jci62543 |
0.457 |
|
| 2012 |
Franchini LF, de Souza FS, Low MJ, Rubinstein M. Positive selection of co-opted mobile genetic elements in a mammalian gene: If you can't beat them, join them. Mobile Genetic Elements. 2: 106-109. PMID 22934245 DOI: 10.4161/Mge.20267 |
0.54 |
|
| 2011 |
Franchini LF, López-Leal R, Nasif S, Beati P, Gelman DM, Low MJ, de Souza FJ, Rubinstein M. Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons. Proceedings of the National Academy of Sciences of the United States of America. 108: 15270-5. PMID 21876128 DOI: 10.1073/Pnas.1104997108 |
0.536 |
|
| 2011 |
Rubinstein M, Low MJ. The smoking gun in nicotine-induced anorexia. Cell Metabolism. 14: 145-7. PMID 21803282 DOI: 10.1016/J.Cmet.2011.07.006 |
0.422 |
|
| 2011 |
Bello EP, Mateo Y, Gelman DM, Noaín D, Shin JH, Low MJ, Alvarez VA, Lovinger DM, Rubinstein M. Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors. Nature Neuroscience. 14: 1033-8. PMID 21743470 DOI: 10.1038/Nn.2862 |
0.535 |
|
| 2011 |
Lee AK, Smart JL, Rubinstein M, Low MJ, Tse A. Reciprocal regulation of TREK-1 channels by arachidonic acid and CRH in mouse corticotropes. Endocrinology. 152: 1901-10. PMID 21343252 DOI: 10.1210/En.2010-1066 |
0.574 |
|
| 2011 |
Richard CD, Tolle V, Low MJ. Meal pattern analysis in neural-specific proopiomelanocortin-deficient mice. European Journal of Pharmacology. 660: 131-8. PMID 21211523 DOI: 10.1016/j.ejphar.2010.12.022 |
0.34 |
|
| 2011 |
de Souza FS, Nasif S, López-Leal R, Levi DH, Low MJ, Rubinsten M. The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2. European Journal of Pharmacology. 660: 181-7. PMID 21211522 DOI: 10.1016/j.ejphar.2010.10.114 |
0.339 |
|
| 2011 |
Franchini LF, López-Leal R, Nasif S, Beati P, Gelman DM, Low MJ, De Souza FJS, Rubinstein M. Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 37 (15270-15275)) Proceedings of the National Academy of Sciences of the United States of America. 108: 20850. DOI: 10.1073/Pnas.1119060109 |
0.41 |
|
| 2010 |
GarcÃa-Tornadu I, Risso G, Perez-Millan MI, Noain D, Diaz-Torga G, Low MJ, Rubinstein M, Becu-Villalobos D. Neurotransmitter modulation of the GHRH-GH axis. Frontiers of Hormone Research. 38: 59-69. PMID 20616496 DOI: 10.1159/000318495 |
0.594 |
|
| 2010 |
Gallagher SK, Witkovsky P, Roux MJ, Low MJ, Otero-Corchon V, Hentges ST, Vigh J. beta-Endorphin expression in the mouse retina. The Journal of Comparative Neurology. 518: 3130-48. PMID 20533364 DOI: 10.1002/Cne.22387 |
0.68 |
|
| 2009 |
Hentges ST, Otero-Corchon V, Pennock RL, King CM, Low MJ. Proopiomelanocortin expression in both GABA and glutamate neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13684-90. PMID 19864580 DOI: 10.1523/Jneurosci.3770-09.2009 |
0.709 |
|
| 2009 |
GarcÃa-Tornadú I, DÃaz-Torga G, Risso GS, Silveyra P, Cataldi N, Ramirez MC, Low MJ, Libertun C, Becu-Villalobos D. Hypothalamic orexin, OX1, alphaMSH, NPY and MCRs expression in dopaminergic D2R knockout mice. Neuropeptides. 43: 267-74. PMID 19570576 DOI: 10.1016/J.Npep.2009.06.002 |
0.398 |
|
| 2009 |
Sharpe AL, Low MJ. Proopiomelanocortin peptides are not essential for development of ethanol-induced behavioral sensitization. Alcoholism, Clinical and Experimental Research. 33: 1202-7. PMID 19389193 DOI: 10.1111/J.1530-0277.2009.00944.X |
0.695 |
|
| 2009 |
Hauge-Evans AC, King AJ, Carmignac D, Richardson CC, Robinson IC, Low MJ, Christie MR, Persaud SJ, Jones PM. Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function. Diabetes. 58: 403-11. PMID 18984743 DOI: 10.2337/Db08-0792 |
0.303 |
|
| 2008 |
Arttamangkul S, Quillinan N, Low MJ, von Zastrow M, Pintar J, Williams JT. Differential activation and trafficking of micro-opioid receptors in brain slices. Molecular Pharmacology. 74: 972-9. PMID 18612077 DOI: 10.1124/Mol.108.048512 |
0.518 |
|
| 2008 |
Gong L, Yao F, Hockman K, Heng HH, Morton GJ, Takeda K, Akira S, Low MJ, Rubinstein M, MacKenzie RG. Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis. Endocrinology. 149: 3346-54. PMID 18403487 DOI: 10.1210/En.2007-0945 |
0.614 |
|
| 2008 |
Kelly MA, Low MJ, Rubinstein M, Phillips TJ. Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice. Genes, Brain, and Behavior. 7: 568-77. PMID 18363855 DOI: 10.1111/J.1601-183X.2008.00392.X |
0.572 |
|
| 2008 |
Doherty JM, Masten VL, Powell SB, Ralph RJ, Klamer D, Low MJ, Geyer MA. Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2648-56. PMID 18075489 DOI: 10.1038/Sj.Npp.1301657 |
0.39 |
|
| 2008 |
Tolle V, Low MJ. In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice. Diabetes. 57: 86-94. PMID 17909095 DOI: 10.2337/Db07-0733 |
0.448 |
|
| 2007 |
Appleyard SM, Marks D, Kobayashi K, Okano H, Low MJ, Andresen MC. Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13292-302. PMID 18045923 DOI: 10.1523/Jneurosci.3502-07.2007 |
0.357 |
|
| 2007 |
Santangelo AM, de Souza FS, Franchini LF, Bumaschny VF, Low MJ, Rubinstein M. Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene. Plos Genetics. 3: 1813-26. PMID 17922573 DOI: 10.1371/Journal.Pgen.0030166 |
0.545 |
|
| 2007 |
Bumaschny VF, de Souza FS, López Leal RA, Santangelo AM, Baetscher M, Levi DH, Low MJ, Rubinstein M. Transcriptional regulation of pituitary POMC is conserved at the vertebrate extremes despite great promoter sequence divergence. Molecular Endocrinology (Baltimore, Md.). 21: 2738-49. PMID 17698954 DOI: 10.1210/Me.2006-0557 |
0.538 |
|
| 2007 |
Petraschka M, Li S, Gilbert TL, Westenbroek RE, Bruchas MR, Schreiber S, Lowe J, Low MJ, Pintar JE, Chavkin C. The absence of endogenous beta-endorphin selectively blocks phosphorylation and desensitization of mu opioid receptors following partial sciatic nerve ligation. Neuroscience. 146: 1795-807. PMID 17467916 DOI: 10.1016/J.Neuroscience.2007.03.029 |
0.335 |
|
| 2007 |
Vinkers CH, Risbrough VB, Geyer MA, Caldwell S, Low MJ, Hauger RL. Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating. Pharmacology, Biochemistry, and Behavior. 86: 550-8. PMID 17324452 DOI: 10.1016/J.Pbb.2007.01.018 |
0.416 |
|
| 2007 |
Smart JL, Tolle V, Otero-Corchon V, Low MJ. Central dysregulation of the hypothalamic-pituitary-adrenal axis in neuron-specific proopiomelanocortin-deficient mice. Endocrinology. 148: 647-59. PMID 17095588 DOI: 10.1210/En.2006-0990 |
0.645 |
|
| 2007 |
Hayward MD, Low MJ. The contribution of endogenous opioids to food reward is dependent on sex and background strain. Neuroscience. 144: 17-25. PMID 17049174 DOI: 10.1016/J.Neuroscience.2006.08.067 |
0.39 |
|
| 2007 |
Lei L, Murphy JG, Smart JL, Low MJ, Fan W. Delineation of a novel direct pathway from the hypothalamic proopiomelanocortin (POMC) neurons projecting to the brainstem raphe pallidus (RPa) melanocortin 4 receptor (MC4R) neurons The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A460-A |
0.58 |
|
| 2006 |
Hayward MD, Schaich-Borg A, Pintar JE, Low MJ. Differential involvement of endogenous opioids in sucrose consumption and food reinforcement. Pharmacology, Biochemistry, and Behavior. 85: 601-11. PMID 17166571 DOI: 10.1016/J.Pbb.2006.10.015 |
0.387 |
|
| 2006 |
GarcÃa-Tornadú I, Rubinstein M, Gaylinn BD, Hill D, Arany E, Low MJ, DÃaz-Torga G, Becu-Villalobos D. GH in the dwarf dopaminergic D2 receptor knockout mouse: somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin. The Journal of Endocrinology. 190: 611-9. PMID 17003262 DOI: 10.1677/Joe.1.06902 |
0.594 |
|
| 2006 |
Risbrough VB, Masten VL, Caldwell S, Paulus MP, Low MJ, Geyer MA. Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2349-58. PMID 16855533 DOI: 10.1038/Sj.Npp.1301161 |
0.405 |
|
| 2006 |
Cristina C, GarcÃa-Tornadú I, DÃaz-Torga G, Rubinstein M, Low MJ, Becú-Villalobos D. Dopaminergic D2 receptor knockout mouse: an animal model of prolactinoma. Frontiers of Hormone Research. 35: 50-63. PMID 16809922 DOI: 10.1159/000094308 |
0.542 |
|
| 2006 |
Job MO, Ramachandra V, Anders S, Low MJ, Gonzales RA. Reduced basal and ethanol stimulation of striatal extracellular dopamine concentrations in dopamine D2 receptor knockout mice. Synapse (New York, N.Y.). 60: 158-64. PMID 16715495 DOI: 10.1002/Syn.20283 |
0.359 |
|
| 2006 |
Smart JL, Tolle V, Low MJ. Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice. The Journal of Clinical Investigation. 116: 495-505. PMID 16440060 DOI: 10.1172/Jci25243 |
0.623 |
|
| 2006 |
Kumar TR, Schuff KG, Nusser KD, Low MJ. Gonadotroph-specific expression of the human follicle stimulating hormone beta gene in transgenic mice. Molecular and Cellular Endocrinology. 247: 103-15. PMID 16414183 DOI: 10.1016/J.Mce.2005.12.006 |
0.329 |
|
| 2006 |
Cox BA, Low M, Saunders K, Shupert C. Should you count your mice before they're weaned? Start counting Lab Animal.. 35: 17. PMID 16382229 DOI: 10.1038/Laban0106-17 |
0.354 |
|
| 2005 |
Hentges ST, Low MJ, Williams JT. Differential regulation of synaptic inputs by constitutively released endocannabinoids and exogenous cannabinoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9746-51. PMID 16237178 DOI: 10.1523/Jneurosci.2769-05.2005 |
0.723 |
|
| 2005 |
Elmer GI, Pieper JO, Levy J, Rubinstein M, Low MJ, Grandy DK, Wise RA. Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice. Psychopharmacology. 182: 33-44. PMID 16136297 DOI: 10.1007/S00213-005-0051-2 |
0.56 |
|
| 2005 |
Hayward MD, Low MJ. Naloxone's suppression of spontaneous and food-conditioned locomotor activity is diminished in mice lacking either the dopamine D(2) receptor or enkephalin. Brain Research. Molecular Brain Research. 140: 91-8. PMID 16125819 DOI: 10.1016/J.Molbrainres.2005.07.016 |
0.426 |
|
| 2005 |
de Souza FS, Bumaschny VF, Low MJ, Rubinstein M. Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes. Molecular Biology and Evolution. 22: 2417-27. PMID 16093565 DOI: 10.1093/Molbev/Msi236 |
0.519 |
|
| 2005 |
Cristina C, DÃaz-Torga G, Baldi A, Góngora A, Rubinstein M, Low MJ, Becú-Villalobos D. Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice. Endocrinology. 146: 2952-62. PMID 15817666 DOI: 10.1210/En.2004-1445 |
0.553 |
|
| 2005 |
Appleyard SM, Bailey TW, Doyle MW, Jin YH, Smart JL, Low MJ, Andresen MC. Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3578-85. PMID 15814788 DOI: 10.1523/Jneurosci.4177-04.2005 |
0.613 |
|
| 2005 |
de Souza FS, Santangelo AM, Bumaschny V, Avale ME, Smart JL, Low MJ, Rubinstein M. Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting. Molecular and Cellular Biology. 25: 3076-86. PMID 15798195 DOI: 10.1128/Mcb.25.8.3076-3086.2005 |
0.704 |
|
| 2005 |
Slominski A, Plonka PM, Pisarchik A, Smart JL, Tolle V, Wortsman J, Low MJ. Preservation of eumelanin hair pigmentation in proopiomelanocortin-deficient mice on a nonagouti (a/a) genetic background. Endocrinology. 146: 1245-53. PMID 15564334 DOI: 10.1210/En.2004-0733 |
0.603 |
|
| 2004 |
Low MJ. Clinical endocrinology and metabolism. The somatostatin neuroendocrine system: physiology and clinical relevance in gastrointestinal and pancreatic disorders. Best Practice & Research. Clinical Endocrinology & Metabolism. 18: 607-22. PMID 15533778 DOI: 10.1016/J.Beem.2004.08.005 |
0.36 |
|
| 2004 |
Low MJ. Role of proopiomelanocortin neurons and peptides in the regulation of energy homeostasis. Journal of Endocrinological Investigation. 27: 95-100. PMID 15481808 |
0.326 |
|
| 2004 |
Hayward MD, Hansen ST, Pintar JE, Low MJ. Operant self-administration of ethanol in C57BL/6 mice lacking beta-endorphin and enkephalin. Pharmacology, Biochemistry, and Behavior. 79: 171-81. PMID 15388297 DOI: 10.1016/J.Pbb.2004.07.002 |
0.328 |
|
| 2004 |
Doyle MW, Bailey TW, Jin YH, Appleyard SM, Low MJ, Andresen MC. Strategies for cellular identification in nucleus tractus solitarius slices. Journal of Neuroscience Methods. 137: 37-48. PMID 15196825 DOI: 10.1016/J.Jneumeth.2004.02.007 |
0.35 |
|
| 2004 |
Overstreet LS, Hentges ST, Bumaschny VF, de Souza FS, Smart JL, Santangelo AM, Low MJ, Westbrook GL, Rubinstein M. A transgenic marker for newly born granule cells in dentate gyrus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3251-9. PMID 15056704 DOI: 10.1523/Jneurosci.5173-03.2004 |
0.787 |
|
| 2004 |
Hentges ST, Nishiyama M, Overstreet LS, Stenzel-Poore M, Williams JT, Low MJ. GABA release from proopiomelanocortin neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1578-83. PMID 14973227 DOI: 10.1523/Jneurosci.3952-03.2004 |
0.742 |
|
| 2004 |
Avale ME, Falzone TL, Gelman DM, Low MJ, Grandy DK, Rubinstein M. The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder. Molecular Psychiatry. 9: 718-26. PMID 14699433 DOI: 10.1038/Sj.Mp.4001474 |
0.755 |
|
| 2004 |
Tomiyama K, McNamara FN, Clifford JJ, Kinsella A, Drago J, Fuchs S, Grandy DK, Low MJ, Rubinstein M, Tighe O, Croke DT, Koshikawa N, Waddington JL. Comparative phenotypic resolution of spontaneous, D2-like and D1-like agonist-induced orofacial movement topographies in congenic mutants with dopamine D2 vs. D3 receptor "knockout". Synapse (New York, N.Y.). 51: 71-81. PMID 14579426 DOI: 10.1002/Syn.10284 |
0.509 |
|
| 2004 |
O'Sullivan GJ, Croke DT, Tighe O, Kinsella A, Grandy DK, Low MJ, Rubinstein M, Sibley DR, Waddington JL. P.2.27 Topographical evaluation of spontaneous and agonist-induced behaviour in mutants with congenic dopamine D4 versus D5 receptor knockout European Neuropsychopharmacology. 14. DOI: 10.1016/S0924-977X(04)90050-8 |
0.343 |
|
| 2003 |
Kelly MA, Low MJ, Phillips TJ, Wakeland EK, Yanagisawa M. The mapping of quantitative trait loci underlying strain differences in locomotor activity between 129S6 and C57BL/6J mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 14: 692-702. PMID 14694905 DOI: 10.1007/S00335-003-2273-0 |
0.313 |
|
| 2003 |
Kuchenbauer F, Theodoropoulou M, Hopfner U, Stalla J, Renner U, Tonn JC, Low MJ, Arzt E, Stalla GK, Páez-Pereda M. Laminin inhibits lactotroph proliferation and is reduced in early prolactinoma development. Molecular and Cellular Endocrinology. 207: 13-20. PMID 12972179 DOI: 10.1016/S0303-7207(03)00237-5 |
0.396 |
|
| 2003 |
Gelman DM, NoaÃn D, Avale ME, Otero V, Low MJ, Rubinstein M. Transgenic mice engineered to target Cre/loxP-mediated DNA recombination into catecholaminergic neurons. Genesis (New York, N.Y. : 2000). 36: 196-202. PMID 12929090 DOI: 10.1002/Gene.10217 |
0.593 |
|
| 2003 |
Smart JL, Low MJ. Lack of proopiomelanocortin peptides results in obesity and defective adrenal function but normal melanocyte pigmentation in the murine C57BL/6 genetic background. Annals of the New York Academy of Sciences. 994: 202-10. PMID 12851317 DOI: 10.1111/J.1749-6632.2003.Tb03181.X |
0.59 |
|
| 2003 |
Low MJ, Hayward MD, Appleyard SM, Rubinstein M. State-dependent modulation of feeding behavior by proopiomelanocortin-derived beta-endorphin. Annals of the New York Academy of Sciences. 994: 192-201. PMID 12851316 DOI: 10.1111/J.1749-6632.2003.Tb03180.X |
0.554 |
|
| 2003 |
Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro J, Zigman JM, Cone RD, Elmquist JK. Central serotonin and melanocortin pathways regulating energy homeostasis. Annals of the New York Academy of Sciences. 994: 169-74. PMID 12851313 DOI: 10.1111/J.1749-6632.2003.Tb03177.X |
0.739 |
|
| 2003 |
Palmer AA, Low MJ, Grandy DK, Phillips TJ. Effects of a Drd2 deletion mutation on ethanol-induced locomotor stimulation and sensitization suggest a role for epistasis. Behavior Genetics. 33: 311-24. PMID 12837020 DOI: 10.1023/A:1023450625826 |
0.338 |
|
| 2003 |
Katz JL, Chausmer AL, Elmer GI, Rubinstein M, Low MJ, Grandy DK. Cocaine-induced locomotor activity and cocaine discrimination in dopamine D4 receptor mutant mice. Psychopharmacology. 170: 108-14. PMID 12783155 DOI: 10.1007/S00213-003-1513-Z |
0.544 |
|
| 2003 |
Appleyard SM, Hayward M, Young JI, Butler AA, Cone RD, Rubinstein M, Low MJ. A role for the endogenous opioid beta-endorphin in energy homeostasis. Endocrinology. 144: 1753-60. PMID 12697680 DOI: 10.1210/En.2002-221096 |
0.537 |
|
| 2003 |
Ibrahim N, Bosch MA, Smart JL, Qiu J, Rubinstein M, Rønnekleiv OK, Low MJ, Kelly MJ. Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels. Endocrinology. 144: 1331-40. PMID 12639916 DOI: 10.1210/En.2002-221033 |
0.665 |
|
| 2003 |
Cowley MA, Smith RG, Diano S, Tschöp M, Pronchuk N, Grove KL, Strasburger CJ, Bidlingmaier M, Esterman M, Heiman ML, Garcia-Segura LM, Nillni EA, Mendez P, Low MJ, Sotonyi P, et al. The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron. 37: 649-61. PMID 12597862 DOI: 10.1016/S0896-6273(03)00063-1 |
0.409 |
|
| 2003 |
Paez-Pereda M, Giacomini D, Refojo D, Nagashima AC, Hopfner U, Grubler Y, Chervin A, Goldberg V, Goya R, Hentges ST, Low MJ, Holsboer F, Stalla GK, Arzt E. Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk. Proceedings of the National Academy of Sciences of the United States of America. 100: 1034-9. PMID 12552124 DOI: 10.1073/Pnas.0237312100 |
0.719 |
|
| 2002 |
Ensinck JW, Baskin DG, Vahl TP, Vogel RE, Laschansky EC, Francis BH, Hoffman RC, Krakover JD, Stamm MR, Low MJ, Rubinstein M, Otero-Corchon V, D'Alessio DA. Thrittene, Homologous with Somatostatin-28(1-13), Is a Novel Peptide in Mammalian Gut and Circulation. Endocrinology. 143: 2599-2609. PMID 28201530 DOI: 10.1210/endo.143.7.8904 |
0.384 |
|
| 2002 |
Refojo D, Kovalovsky D, Young JI, Rubinstein M, Holsboer F, Reul JM, Low MJ, Arzt E. Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice. Journal of Neuroimmunology. 131: 126-34. PMID 12458044 DOI: 10.1016/S0165-5728(02)00268-0 |
0.431 |
|
| 2002 |
Hentges ST, Low MJ. Ovarian dependence for pituitary tumorigenesis in D2 dopamine receptor-deficient mice. Endocrinology. 143: 4536-43. PMID 12446580 DOI: 10.1210/En.2002-220421 |
0.741 |
|
| 2002 |
Ralph-Williams RJ, Lehmann-Masten V, Otero-Corchon V, Low MJ, Geyer MA. Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9604-11. PMID 12417685 DOI: 10.1523/Jneurosci.22-21-09604.2002 |
0.429 |
|
| 2002 |
Schuff KG, Hentges ST, Kelly MA, Binart N, Kelly PA, Iuvone PM, Asa SL, Low MJ. Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms. The Journal of Clinical Investigation. 110: 973-81. PMID 12370275 DOI: 10.1172/Jci15912 |
0.742 |
|
| 2002 |
Chausmer AL, Elmer GI, Rubinstein M, Low MJ, Grandy DK, Katz JL. Cocaine-induced locomotor activity and cocaine discrimination in dopamine D2 receptor mutant mice. Psychopharmacology. 163: 54-61. PMID 12185400 DOI: 10.1007/s00213-002-1142-y |
0.469 |
|
| 2002 |
Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, Low MJ, Ghatei MA, Cone RD, Bloom SR. Gut hormone PYY(3-36) physiologically inhibits food intake. Nature. 418: 650-4. PMID 12167864 DOI: 10.1038/Nature00887 |
0.383 |
|
| 2002 |
RamÃrez JL, Mouchantaf R, Kumar U, Otero Corchon V, Rubinstein M, Low MJ, Patel YC. Brain somatostatin receptors are up-regulated in somatostatin-deficient mice. Molecular Endocrinology (Baltimore, Md.). 16: 1951-63. PMID 12145348 DOI: 10.1210/Me.2002-0068 |
0.576 |
|
| 2002 |
Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK. Activation of central melanocortin pathways by fenfluramine. Science (New York, N.Y.). 297: 609-11. PMID 12142539 DOI: 10.1126/Science.1072327 |
0.734 |
|
| 2002 |
Ensinck JW, Baskin DG, Vahl TP, Vogel RE, Laschansky EC, Francis BH, Hoffman RC, Krakover JD, Stamm MR, Low MJ, Rubinstein M, Otero-Corchon V, D'Alessio DA. Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation. Endocrinology. 143: 2599-609. PMID 12072392 DOI: 10.1210/Endo.143.7.8904 |
0.522 |
|
| 2002 |
Liu YL, Yakar S, Otero-Corchon V, Low MJ, Liu JL. Ghrelin gene expression is age-dependent and influenced by gender and the level of circulating IGF-I. Molecular and Cellular Endocrinology. 189: 97-103. PMID 12039068 DOI: 10.1016/S0303-7207(01)00742-0 |
0.375 |
|
| 2002 |
Elmer GI, Pieper JO, Rubinstein M, Low MJ, Grandy DK, Wise RA. Failure of intravenous morphine to serve as an effective instrumental reinforcer in dopamine D2 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: RC224. PMID 12006606 |
0.515 |
|
| 2002 |
Díaz-Torga G, Feierstein C, Libertun C, Gelman D, Kelly MA, Low MJ, Rubinstein M, Becú-Villalobos D. Disruption of the D2 dopamine receptor alters GH and IGF-I secretion and causes dwarfism in male mice. Endocrinology. 143: 1270-9. PMID 11897683 DOI: 10.1210/Endo.143.4.8750 |
0.584 |
|
| 2002 |
Nir I, Harrison JM, Haque R, Low MJ, Grandy DK, Rubinstein M, Iuvone PM. Dysfunctional light-evoked regulation of cAMP in photoreceptors and abnormal retinal adaptation in mice lacking dopamine D4 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2063-73. PMID 11896146 DOI: 10.1523/Jneurosci.22-06-02063.2002 |
0.497 |
|
| 2002 |
Falzone TL, Gelman DM, Young JI, Grandy DK, Low MJ, Rubinstein M. Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear. The European Journal of Neuroscience. 15: 158-64. PMID 11860516 DOI: 10.1046/J.0953-816X.2001.01842.X |
0.772 |
|
| 2002 |
Buckmaster PS, Otero-Corchón V, Rubinstein M, Low MJ. Heightened seizure severity in somatostatin knockout mice. Epilepsy Research. 48: 43-56. PMID 11823109 DOI: 10.1016/S0920-1211(01)00318-7 |
0.516 |
|
| 2002 |
Hayward MD, Pintar JE, Low MJ. Selective Reward Deficit in Mice Lacking β-Endorphin and Enkephalin The Journal of Neuroscience. 22: 8251-8258. DOI: 10.1523/Jneurosci.22-18-08251.2002 |
0.36 |
|
| 2001 |
Cone RD, Cowley MA, Butler AA, Fan W, Marks DL, Low MJ. The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 25: S63-7. PMID 11840218 DOI: 10.1038/Sj.Ijo.0801913 |
0.464 |
|
| 2001 |
Hayward MD, Low MJ. The effect of naloxone on operant behavior for food reinforcers in DBA/2 mice. Brain Research Bulletin. 56: 537-43. PMID 11786239 DOI: 10.1016/S0361-9230(01)00626-8 |
0.358 |
|
| 2001 |
Clifford JJ, Kinsella A, Tighe O, Rubinstein M, Grandy DK, Low MJ, Croke DT, Waddington JL. Comparative, topographically-based evaluation of behavioural phenotype and specification of D(1)-like:D(2) interactions in a line of incipient congenic mice with D(2) dopamine receptor 'knockout'. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 527-36. PMID 11557166 DOI: 10.1016/S0893-133X(01)00246-9 |
0.552 |
|
| 2001 |
Low MJ, Otero-Corchon V, Parlow AF, Ramirez JL, Kumar U, Patel YC, Rubinstein M. Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth. The Journal of Clinical Investigation. 107: 1571-80. PMID 11413165 DOI: 10.1172/Jci11941 |
0.535 |
|
| 2001 |
Cowley MA, Smart JL, Rubinstein M, Cerdán MG, Diano S, Horvath TL, Cone RD, Low MJ. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature. 411: 480-4. PMID 11373681 DOI: 10.1038/35078085 |
0.703 |
|
| 2001 |
Rubinstein M, Cepeda C, Hurst RS, Flores-Hernandez J, Ariano MA, Falzone TL, Kozell LB, Meshul CK, Bunzow JR, Low MJ, Levine MS, Grandy DK. Dopamine D4 receptor-deficient mice display cortical hyperexcitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 3756-63. PMID 11356863 DOI: 10.1523/Jneurosci.21-11-03756.2001 |
0.777 |
|
| 2001 |
Dockstader CL, Rubinstein M, Grandy DK, Low MJ, van der Kooy D. The D2 receptor is critical in mediating opiate motivation only in opiate-dependent and withdrawn mice. The European Journal of Neuroscience. 13: 995-1001. PMID 11264672 DOI: 10.1046/J.1460-9568.2001.01455.X |
0.574 |
|
| 2001 |
Chen JF, Moratalla R, Impagnatiello F, Grandy DK, Cuellar B, Rubinstein M, Beilstein MA, Hackett E, Fink JS, Low MJ, Ongini E, Schwarzschild MA. The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 98: 1970-5. PMID 11172060 DOI: 10.1073/Pnas.98.4.1970 |
0.643 |
|
| 2001 |
Cepeda C, Hurst RS, Altemus KL, Flores-Hernández J, Calvert CR, Jokel ES, Grandy DK, Low MJ, Rubinstein M, Ariano MA, Levine MS. Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor-deficient mice. Journal of Neurophysiology. 85: 659-70. PMID 11160501 DOI: 10.1152/Jn.2001.85.2.659 |
0.586 |
|
| 2001 |
Tang K, Low MJ, Grandy DK, Lovinger DM. Dopamine-dependent synaptic plasticity in striatum during in vivo development. Proceedings of the National Academy of Sciences of the United States of America. 98: 1255-60. PMID 11158626 DOI: 10.1073/Pnas.98.3.1255 |
0.301 |
|
| 2001 |
Rubinstein M, Cepeda C, Hurst RS, Flores-Hernandez J, Ariano MA, Falzone TL, Kozell LB, Meshul CK, Bunzow JR, Low MJ, Levine MS, Grandy DK. Dopamine D4Receptor-Deficient Mice Display Cortical Hyperexcitability The Journal of Neuroscience. 21: 3756-3763. DOI: 10.1523/JNEUROSCI.21-11-03756.2001 |
0.699 |
|
| 2000 |
Grahame NJ, Mosemiller AK, Low MJ, Froehlich JC. Naltrexone and alcohol drinking in mice lacking beta-endorphin by site-directed mutagenesis. Pharmacology, Biochemistry, and Behavior. 67: 759-66. PMID 11166066 DOI: 10.1016/S0091-3057(00)00411-1 |
0.312 |
|
| 2000 |
Cunningham CL, Howard MA, Gill SJ, Rubinstein M, Low MJ, Grandy DK. Ethanol-conditioned place preference is reduced in dopamine D2 receptor-deficient mice. Pharmacology, Biochemistry, and Behavior. 67: 693-9. PMID 11166059 DOI: 10.1016/S0091-3057(00)00414-7 |
0.56 |
|
| 2000 |
Mogil JS, Grisel JE, Hayward MD, Bales JR, Rubinstein M, Belknap JK, Low MJ. Disparate spinal and supraspinal opioid antinociceptive responses in beta-endorphin-deficient mutant mice. Neuroscience. 101: 709-17. PMID 11113319 DOI: 10.1016/S0306-4522(00)00422-X |
0.528 |
|
| 2000 |
Risinger FO, Freeman PA, Rubinstein M, Low MJ, Grandy DK. Lack of operant ethanol self-administration in dopamine D2 receptor knockout mice. Psychopharmacology. 152: 343-50. PMID 11105945 DOI: 10.1007/S002130000548 |
0.54 |
|
| 2000 |
Slugg RM, Hayward MD, Ronnekleiv OK, Low MJ, Kelly MJ. Effect of the mu-opioid agonist DAMGO on medial basal hypothalamic neurons in beta-endorphin knockout mice. Neuroendocrinology. 72: 208-17. PMID 11070424 DOI: 10.1159/000054589 |
0.421 |
|
| 2000 |
Tseng KY, Roubert C, Do L, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Gershanik OS, Murer MG, Giros B, Raisman-Vozari R. Selective increase of Nurr1 mRNA expression in mesencephalic dopaminergic neurons of D2 dopamine receptor-deficient mice. Brain Research. Molecular Brain Research. 80: 1-6. PMID 11039723 DOI: 10.1016/S0169-328X(00)00107-8 |
0.738 |
|
| 2000 |
Murer MG, Dziewczapolski G, Salin P, Vila M, Tseng KY, Ruberg M, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Hirsch E, Raisman-Vozari R, Gershanik O. The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice. Neuroscience. 99: 643-50. PMID 10974427 DOI: 10.1016/S0306-4522(00)00223-2 |
0.731 |
|
| 2000 |
Zahniser NR, Simosky JK, Mayfield RD, Negri CA, Hanania T, Larson GA, Kelly MA, Grandy DK, Rubinstein M, Low MJ, Fredholm BB. Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5949-57. PMID 10934242 DOI: 10.1523/Jneurosci.20-16-05949.2000 |
0.527 |
|
| 2000 |
Coste SC, Kesterson RA, Heldwein KA, Stevens SL, Heard AD, Hollis JH, Murray SE, Hill JK, Pantely GA, Hohimer AR, Hatton DC, Phillips TJ, Finn DA, Low MJ, Rittenberg MB, et al. Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2. Nature Genetics. 24: 403-9. PMID 10742107 DOI: 10.1038/74255 |
0.41 |
|
| 2000 |
Defagot MC, Falzone TL, Low MJ, Grandy DK, Rubinstein M, Antonelli MC. Quantitative analysis of the dopamine D4 receptor in the mouse brain. Journal of Neuroscience Research. 59: 202-8. PMID 10650878 DOI: 10.1002/(Sici)1097-4547(20000115)59:2<202::Aid-Jnr6>3.0.Co;2-5 |
0.744 |
|
| 1999 |
Asa SL, Kelly MA, Grandy DK, Low MJ. Pituitary Lactotroph Adenomas Develop after Prolonged Lactotroph Hyperplasia in Dopamine D2 Receptor-Deficient Mice1. Endocrinology. 140: 5348-5355. PMID 28200743 DOI: 10.1210/endo.140.11.7118 |
0.316 |
|
| 1999 |
Asa SL, Kelly MA, Grandy DK, Low MJ. Pituitary lactotroph adenomas develop after prolonged lactotroph hyperplasia in dopamine D2 receptor-deficient mice. Endocrinology. 140: 5348-55. PMID 10537166 DOI: 10.1210/Endo.140.11.7118 |
0.413 |
|
| 1999 |
Dulawa SC, Grandy DK, Low MJ, Paulus MP, Geyer MA. Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9550-6. PMID 10531457 DOI: 10.1523/Jneurosci.19-21-09550.1999 |
0.371 |
|
| 1999 |
Graham KE, Nusser KD, Low MJ. LbetaT2 gonadotroph cells secrete follicle stimulating hormone (FSH) in response to active A. The Journal of Endocrinology. 162: R1-5. PMID 10467239 DOI: 10.1677/Joe.0.162R001 |
0.31 |
|
| 1999 |
Hayward MD, Low MJ. Targeted mutagenesis of the murine opioid system. Results and Problems in Cell Differentiation. 26: 169-91. PMID 10453464 DOI: 10.1007/978-3-540-49421-8_8 |
0.362 |
|
| 1999 |
Grisel JE, Mogil JS, Grahame NJ, Rubinstein M, Belknap JK, Crabbe JC, Low MJ. Ethanol oral self-administration is increased in mutant mice with decreased beta-endorphin expression. Brain Research. 835: 62-7. PMID 10448196 DOI: 10.1016/S0006-8993(99)01384-0 |
0.551 |
|
| 1999 |
Ralph RJ, Varty GB, Kelly MA, Wang YM, Caron MG, Rubinstein M, Grandy DK, Low MJ, Geyer MA. The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4627-33. PMID 10341260 DOI: 10.1523/Jneurosci.19-11-04627.1999 |
0.55 |
|
| 1999 |
Wilke RA, Lupardus PJ, Grandy DK, Rubinstein M, Low MJ, Jackson MB. K+ channel modulation in rodent neurohypophysial nerve terminals by sigma receptors and not by dopamine receptors. The Journal of Physiology. 517: 391-406. PMID 10332090 DOI: 10.1111/J.1469-7793.1999.00391.X |
0.522 |
|
| 1999 |
Dickinson SD, Sabeti J, Larson GA, Giardina K, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Gerhardt GA, Zahniser NR. Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum. Journal of Neurochemistry. 72: 148-56. PMID 9886065 DOI: 10.1046/J.1471-4159.1999.0720148.X |
0.567 |
|
| 1998 |
Phillips TJ, Brown KJ, Burkhart-Kasch S, Wenger CD, Kelly MA, Rubinstein M, Grandy DK, Low MJ. Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors. Nature Neuroscience. 1: 610-5. PMID 10196569 DOI: 10.1038/2843 |
0.553 |
|
| 1998 |
Low MJ, Kelly MA, Rubinstein M, Grandy DK. Single genes and complex phenotypes. Molecular Psychiatry. 3: 373-7. PMID 9774768 DOI: 10.1038/Sj.Mp.4000455 |
0.539 |
|
| 1998 |
Grahame NJ, Low MJ, Cunningham CL. Intravenous self-administration of ethanol in beta-endorphin-deficient mice. Alcoholism, Clinical and Experimental Research. 22: 1093-8. PMID 9726280 DOI: 10.1111/J.1530-0277.1998.Tb03706.X |
0.35 |
|
| 1998 |
Young JI, Otero V, Cerdán MG, Falzone TL, Chan EC, Low MJ, Rubinstein M. Authentic cell-specific and developmentally regulated expression of pro-opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6631-40. PMID 9712635 DOI: 10.1523/Jneurosci.18-17-06631.1998 |
0.791 |
|
| 1998 |
Kumar TR, Graham KE, Asa SL, Low MJ. Simian virus 40 T antigen-induced gonadotroph adenomas: a model of human null cell adenomas. Endocrinology. 139: 3342-51. PMID 9645710 DOI: 10.1210/Endo.139.7.6100 |
0.35 |
|
| 1998 |
Kumar TR, Low MJ, Matzuk MM. Genetic rescue of follicle-stimulating hormone beta-deficient mice. Endocrinology. 139: 3289-95. PMID 9645705 DOI: 10.1210/Endo.139.7.6111 |
0.394 |
|
| 1998 |
Kelly MA, Rubinstein M, Phillips TJ, Lessov CN, Burkhart-Kasch S, Zhang G, Bunzow JR, Fang Y, Gerhardt GA, Grandy DK, Low MJ. Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3470-9. PMID 9547254 DOI: 10.1523/Jneurosci.18-09-03470.1998 |
0.596 |
|
| 1998 |
Kelly MA, Rubinstein M, Phillips TJ, Lessov CN, Burkhart-Kasch S, Zhang G, Bunzow JR, Fang Y, Gerhardt GA, Grandy DK, Low MJ. Locomotor Activity in D2 Dopamine Receptor-Deficient Mice Is Determined by Gene Dosage, Genetic Background, and Developmental Adaptations The Journal of Neuroscience. 18: 3470-3479. DOI: 10.1523/JNEUROSCI.18-09-03470.1998 |
0.304 |
|
| 1998 |
Low M, Rubinstein M, Kelly M, Phillips T, Grandy D. 263. Altered behavior in dopamine D2 and D4 receptor gene knockout mice Biological Psychiatry. 43: S79. DOI: 10.1016/S0006-3223(98)90711-9 |
0.507 |
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| 1998 |
Dulawa S, Grandy D, Larson J, Low M, Geyer M. 48. Dopamine D4 receptor-deficient mice exhibit reduced responses to novelty Biological Psychiatry. 43: S15. DOI: 10.1016/S0006-3223(98)90496-6 |
0.303 |
|
| 1998 |
Low MJ, Kelly MA, Rubinstein M, Grandy DK. Single genes and complex phenotypes Molecular Psychiatry. 3: 375-377. |
0.368 |
|
| 1997 |
Chen W, Kelly MA, Opitz-Araya X, Thomas RE, Low MJ, Cone RD. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell. 91: 789-98. PMID 9413988 DOI: 10.1016/S0092-8674(00)80467-5 |
0.336 |
|
| 1997 |
Hnasko R, Khurana S, Shackleford N, Steinmetz R, Low MJ, Ben-Jonathan N. Two distinct pituitary cell lines from mouse intermediate lobe tumors: a cell that produces prolactin-regulating factor and a melanotroph [seecomments]. Endocrinology. 138: 5589-96. PMID 9389547 DOI: 10.1210/Endo.138.12.5656 |
0.357 |
|
| 1997 |
Rubinstein M, Phillips TJ, Bunzow JR, Falzone TL, Dziewczapolski G, Zhang G, Fang Y, Larson JL, McDougall JA, Chester JA, Saez C, Pugsley TA, Gershanik O, Low MJ, Grandy DK. Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell. 90: 991-1001. PMID 9323127 DOI: 10.1016/S0092-8674(00)80365-7 |
0.812 |
|
| 1997 |
Kelly MA, Rubinstein M, Asa SL, Zhang G, Saez C, Bunzow JR, Allen RG, Hnasko R, Ben-Jonathan N, Grandy DK, Low MJ. Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice. Neuron. 19: 103-13. PMID 9247267 DOI: 10.1016/S0896-6273(00)80351-7 |
0.608 |
|
| 1996 |
Rubinstein M, Mogil JS, Japón M, Chan EC, Allen RG, Low MJ. Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 3995-4000. PMID 8633004 DOI: 10.1073/Pnas.93.9.3995 |
0.553 |
|
| 1995 |
Allen RG, Carey C, Parker JD, Mortrud MT, Mellon SH, Low MJ. Targeted ablation of pituitary pre-proopiomelanocortin cells by herpes simplex virus-1 thymidine kinase differentially regulates mRNAs encoding the adrenocorticotropin receptor and aldosterone synthase in the mouse adrenal gland. Molecular Endocrinology (Baltimore, Md.). 9: 1005-16. PMID 7476975 DOI: 10.1210/Mend.9.8.7476975 |
0.401 |
|
| 1994 |
Bunzow JR, Saez C, Mortrud M, Bouvier C, Williams JT, Low M, Grandy DK. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type. Febs Letters. 347: 284-8. PMID 8034019 DOI: 10.1016/0014-5793(94)00561-3 |
0.452 |
|
| 1994 |
Japón MA, Rubinstein M, Low MJ. In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 42: 1117-25. PMID 8027530 DOI: 10.1177/42.8.8027530 |
0.429 |
|
| 1994 |
Mountjoy KG, Mortrud MT, Low MJ, Simerly RB, Cone RD. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Molecular Endocrinology (Baltimore, Md.). 8: 1298-308. PMID 7854347 DOI: 10.1210/Mend.8.10.7854347 |
0.346 |
|
| 1994 |
Low MJ, Simerly RB, Cone RD. Receptors for the melanocortin peptides in the central nervous system Current Opinion in Endocrinology and Diabetes. 1: 79-88. DOI: 10.1097/00060793-199400010-00016 |
0.304 |
|
| 1993 |
Roselli-Rehfuss L, Mountjoy KG, Robbins LS, Mortrud MT, Low MJ, Tatro JB, Entwistle ML, Simerly RB, Cone RD. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proceedings of the National Academy of Sciences of the United States of America. 90: 8856-60. PMID 8415620 DOI: 10.1073/Pnas.90.19.8856 |
0.381 |
|
| 1993 |
Kumar TR, Low MJ. Gonadal steroid hormone regulation of human and mouse follicle stimulating hormone beta-subunit gene expression in vivo. Molecular Endocrinology (Baltimore, Md.). 7: 898-906. PMID 8413314 DOI: 10.1210/Mend.7.7.8413314 |
0.362 |
|
| 1993 |
Rubinstein M, Japón MA, Low MJ. Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker. Nucleic Acids Research. 21: 2613-7. PMID 8392702 DOI: 10.1093/Nar/21.11.2613 |
0.476 |
|
| 1993 |
Rubinstein M, Mortrud M, Liu B, Low MJ. Rat and mouse proopiomelanocortin gene sequences target tissue-specific expression to the pituitary gland but not to the hypothalamus of transgenic mice. Neuroendocrinology. 58: 373-80. PMID 8284022 DOI: 10.1159/000126566 |
0.533 |
|
| 1993 |
Low MJ, Liu B, Hammer GD, Rubinstein M, Allen RG. Post-translational processing of proopiomelanocortin (POMC) in mouse pituitary melanotroph tumors induced by a POMC-simian virus 40 large T antigen transgene. The Journal of Biological Chemistry. 268: 24967-75. PMID 8227058 |
0.457 |
|
| 1992 |
Rubinstein M, Liu B, Goodman RH, Low MJ. Targeted expression of somatostatin in vasopressinergic magnocellular hypothalamic neurons of transgenic mice. Molecular and Cellular Neurosciences. 3: 152-61. PMID 19912855 DOI: 10.1016/1044-7431(92)90019-X |
0.714 |
|
| 1992 |
Kumar TR, Fairchild-Huntress V, Low MJ. Gonadotrope-specific expression of the human follicle-stimulating hormone beta-subunit gene in pituitaries of transgenic mice. Molecular Endocrinology (Baltimore, Md.). 6: 81-90. PMID 1738375 DOI: 10.1210/Mend.6.1.1738375 |
0.365 |
|
| 1992 |
Liu B, Hammer GD, Rubinstein M, Mortrud M, Low MJ. Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice. Molecular and Cellular Biology. 12: 3978-90. PMID 1508198 DOI: 10.1128/Mcb.12.9.3978 |
0.54 |
|
| 1992 |
Hammer GD, Mueller G, Liu B, Petrides JS, Roos BA, Low MJ. Ectopic corticotropin-releasing hormone produced by a transfected cell line chronically activates the pituitary-adrenal axis in transkaryotic rats. Endocrinology. 130: 1975-85. PMID 1312432 DOI: 10.1210/Endo.130.4.1312432 |
0.328 |
|
| 1990 |
Hammer GD, Fairchild-Huntress V, Low MJ. Pituitary-specific and hormonally regulated gene expression directed by the rat proopiomelanocortin promoter in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 4: 1689-97. PMID 2177840 DOI: 10.1210/Mend-4-11-1689 |
0.388 |
|
| 1990 |
Goodman RH, Rehfuss RP, Verhave M, Ventimiglia R, Low MJ. Somatostatin gene regulation: an overview. Metabolism: Clinical and Experimental. 39: 2-5. PMID 1976213 DOI: 10.1016/0026-0495(90)90197-K |
0.509 |
|
| 1989 |
Low MJ, Goodman RH, Ebert KM. Cryptic human growth hormone gene sequences direct gonadotroph-specific expression in transgenic mice. Molecular Endocrinology (Baltimore, Md.). 3: 2028-33. PMID 2576462 DOI: 10.1210/mend-3-12-2028 |
0.556 |
|
| 1988 |
Ebert KM, Low MJ, Overstrom EW, Buonomo FC, Baile CA, Roberts TM, Lee A, Mandel G, Goodman RH. A Moloney MLV-rat somatotropin fusion gene produces biologically active somatotropin in a transgenic pig. Molecular Endocrinology (Baltimore, Md.). 2: 277-83. PMID 3398854 DOI: 10.1210/Mend-2-3-277 |
0.481 |
|
| 1987 |
Sevarino KA, Felix R, Banks CM, Low MJ, Montminy MR, Mandel G, Goodman RH. Cell-specific processing of preprosomatostatin in cultured neuroendocrine cells. The Journal of Biological Chemistry. 262: 4987-93. PMID 2881926 |
0.489 |
|
| 1987 |
Goodman RH, Leiter A, Low MJ, Montminy MR, Tsukada T, Fink JS, Mandel G. Biosynthesis of pancreatic islet hormones. Hepatology (Baltimore, Md.). 7: 36S-41S. PMID 2879784 |
0.618 |
|
| 1987 |
STORK PJ, WARHOL MJ, LOW MJ, GOODMAN RH. Somatostatin Is Targeted to Gonadotrophic Secretory Granules in Transgenic Mice Expressing a Metallothionein-Somatostatin Fusion Gene Annals of the New York Academy of Sciences. 493: 70-73. DOI: 10.1111/j.1749-6632.1987.tb27183.x |
0.55 |
|
| 1986 |
Low MJ, Stork PJ, Hammer RE, Brinster RL, Warhol MJ, Mandel G, Goodman RH. Somatostatin is targeted to the regulated secretory pathway of gonadotrophs in transgenic mice expressing a metallothionein-somatostatin gene. The Journal of Biological Chemistry. 261: 16260-3. PMID 2877985 |
0.578 |
|
| 1986 |
Montminy MR, Low MJ, Tapia-Arancibia L, Reichlin S, Mandel G, Goodman RH. Cyclic AMP regulates somatostatin mRNA accumulation in primary diencephalic cultures and in transfected fibroblast cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1171-6. PMID 2871140 DOI: 10.1523/Jneurosci.06-04-01171.1986 |
0.487 |
|
| 1986 |
Low MJ, Lechan RM, Hammer RE, Brinster RL, Habener JF, Mandel G, Goodman RH. Gonadotroph-specific expression of metallothionein fusion genes in pituitaries of transgenic mice. Science (New York, N.Y.). 231: 1002-4. PMID 2868526 DOI: 10.1126/Science.2868526 |
0.734 |
|
| 1985 |
Goodman RH, Montminy MR, Low MJ, Habener JF. Biosynthesis of rat preprosomatostatin. Advances in Experimental Medicine and Biology. 188: 31-47. PMID 2863939 DOI: 10.1007/978-1-4615-7886-4_3 |
0.582 |
|
| 1985 |
Low MJ, Hammer RE, Goodman RH, Habener JF, Palmiter RD, Brinster RL. Tissue-specific posttranslational processing of pre-prosomatostatin encoded by a metallothionein-somatostatin fusion gene in transgenic mice. Cell. 41: 211-9. PMID 2859927 DOI: 10.1016/0092-8674(85)90075-3 |
0.644 |
|
| 1984 |
Low MJ, Goodman RH, Brinster RL, Palmiter RD, Hammer RE, Habener JF. High plasma levels of immunoreactive somatostatin in transgenic mice expressing a metallothionein-somatostatin fusion gene. Transactions of the Association of American Physicians. 97: 205-9. PMID 6152571 |
0.645 |
|
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