Sekhar P. Reddy - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Physiology Biology, Biomechanics Biophysics, General Biophysics

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Reddy NM, Tamatam CM, Aparna A, Reddy SP. Nrf2 Is Required for Optimal Alveolar-Macrophage-Mediated Apoptotic Neutrophil Clearance after Oxidant Injury. Antioxidants (Basel, Switzerland). 11. PMID 35204093 DOI: 10.3390/antiox11020212  0.428
2021 Noone PM, Reddy SP. Recent advances in dead cell clearance during acute lung injury and repair. Faculty Reviews. 10: 33. PMID 33977286 DOI: 10.12703/r/10-33  0.385
2021 Reddy Potteti H, Noone P, Reddy Tamatam C, Ankireddy A, Noel S, Rabb H, Reddy SP. Nrf2 mediates hypoxia-inducible HIF1α activation in kidney tubular epithelial cells. American Journal of Physiology. Renal Physiology. PMID 33491566 DOI: 10.1152/ajprenal.00501.2020  0.337
2020 Tamatam CM, Reddy NM, Potteti HR, Ankireddy A, Noone PM, Yamamoto M, Kensler TW, Reddy SP. Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice. Scientific Reports. 10: 19034. PMID 33149211 DOI: 10.1038/s41598-020-75834-8  0.462
2020 Huang LS, Kotha SR, Avasarala S, VanScoyk M, Winn RA, Pennathur A, Yashaswini PS, Bandela M, Salgia R, Tyurina YY, Kagan VE, Zhu X, Reddy SP, Sudhadevi T, Punathil-Kannan PK, et al. Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics. The Journal of Biological Chemistry. PMID 32732285 DOI: 10.1074/Jbc.Ra120.012680  0.473
2019 Lazzara PR, David BP, Ankireddy A, Richardson B, Dye K, Ratia KM, Reddy SP, Moore TW. Isoquinoline Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability. Journal of Medicinal Chemistry. PMID 31682434 DOI: 10.1021/Acs.Jmedchem.9B01074  0.303
2019 Rayees S, Joshi JC, Tauseef M, Anwar M, Baweja S, Rochford I, Joshi B, Hollenberg MD, Reddy SP, Mehta D. PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation. Cell Reports. 27: 793-805.e4. PMID 30995477 DOI: 10.1016/J.Celrep.2019.03.053  0.481
2019 Pyaram K, Kumar A, Kim YH, Noel S, Reddy SP, Rabb H, Chang CH. Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis. Cell Reports. 27: 699-707.e4. PMID 30995469 DOI: 10.1016/J.Celrep.2019.03.052  0.341
2018 Richardson B, Jain AD, Potteti H, Lazzara PR, David BP, Tamatam C, Choma E, Skowron K, Dye K, Siddiqui Z, Wang YT, Krunic A, Reddy S, Moore TW. Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear factor (erythroid-derived 2)-like 2 (NRF2)Inhibitors. Journal of Medicinal Chemistry. PMID 30122040 DOI: 10.1021/Acs.Jmedchem.8B01133  0.347
2017 Elangovan IM, Vaz M, Tamatam CR, Potteti HR, Reddy NM, Reddy SP. FOSL1 Promotes Kras-Induced Lung Cancer Through Amphiregulin and Cell Survival Gene Regulation. American Journal of Respiratory Cell and Molecular Biology. PMID 29112457 DOI: 10.1165/Rcmb.2017-0164Oc  0.509
2017 Natarajan V, Ha AW, Dong Y, Reddy NM, Ebenezer DL, Kanteti P, Reddy SP, Usha Raj J, Lei Z, Maienschein-Cline M, Arbieva Z, Harijith A. Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia. Bmc Genomics. 18: 664. PMID 28851267 DOI: 10.1186/S12864-017-4048-0  0.434
2017 Reddy SP, Mehta D. Lung Interstitial Macrophages Redefined: It Is Not That Simple Anymore. American Journal of Respiratory Cell and Molecular Biology. 57: 135-136. PMID 28762771 DOI: 10.1165/Rcmb.2017-0158Ed  0.434
2017 Huang LS, Jiang P, Feghali-Bostwick C, Reddy SP, Garcia JGN, Natarajan V. Lysocardiolipin Acyltransferase Regulates TGF-β Mediated Lung Fibroblast Differentiation. Free Radical Biology & Medicine. PMID 28751023 DOI: 10.1016/J.Freeradbiomed.2017.07.023  0.449
2017 Reddy NM, Kleeberger SR, Kensler TW, Yamamoto M, Hassoun PM, Reddy SP. Correction: Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice. Journal of Immunology (Baltimore, Md. : 1950). 198: 3755. PMID 28416718 DOI: 10.4049/jimmunol.1700291  0.391
2017 Bikkavilli RK, Zerayesus SA, Van Scoyk M, Wilson L, Wu PY, Baskaran A, Tang K, Raheem S, Samuelson BA, Reddy NM, Reddy SP, Cool CD, Kosmider B, Avasarala S, Winn RA. KSRP promotes post-transcriptional destabilization of Spry4 transcripts in non-small cell lung cancer. The Journal of Biological Chemistry. PMID 28275056 DOI: 10.1074/Jbc.M116.757906  0.47
2016 Reddy Potteti H, Reddy Tamatam C, Marreddy R, Reddy NM, Noel S, Rabb H, Reddy SP. NRF2-AKT INTERACTIONS REGULATE HEME OXYGENASE 1 EXPRESSION IN KIDNEY EPITHELIA DURING HYPOXIA AND HYPOXIA-REOXYGENATION. American Journal of Physiology. Renal Physiology. ajprenal.00362.2016. PMID 27582105 DOI: 10.1152/Ajprenal.00362.2016  0.426
2016 Noel S, Arend LJ, Bandapalle S, Reddy SP, Rabb H. Kidney epithelium specific deletion of kelch-like ECH-associated protein 1 (Keap1) causes hydronephrosis in mice. Bmc Nephrology. 17: 110. PMID 27484495 DOI: 10.1186/S12882-016-0310-Y  0.383
2016 Mishra RK, Potteti HR, Tamatam CR, Elangovan I, Reddy SP. c-Jun is Required for NF-κB-dependent, LPS-stimulated Fos-related Antigen-1 Transcription in Alveolar Macrophages. American Journal of Respiratory Cell and Molecular Biology. PMID 27286066 DOI: 10.1165/Rcmb.2016-0028Oc  0.41
2015 Song S, Jacobson KN, McDermott KM, Reddy SP, Cress AE, Tang H, Dudek SM, Black SM, Garcia JG, Makino A, Yuan JX. ATP Promotes Cell Survival Via Regulation of Cytosolic [Ca2+] and Bcl-2/Bax Ratio in Lung Cancer Cells. American Journal of Physiology. Cell Physiology. ajpcell.00092.2015. PMID 26491047 DOI: 10.1152/Ajpcell.00092.2015  0.386
2015 Potteti HR, Rajasekaran S, Rajamohan SB, Tamatam CR, Machireddy N, Reddy SP. Sirtuin 1 Promotes Hyperoxia-induced Lung Epithelial Death Independent of NRF2 Activation. American Journal of Respiratory Cell and Molecular Biology. PMID 26465873 DOI: 10.1165/Rcmb.2014-0056Oc  0.565
2015 Jain AD, Potteti H, Richardson BG, Kingsley L, Luciano JP, Ryuzoji AF, Lee H, Krunic A, Mesecar AD, Reddy SP, Moore TW. Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators. European Journal of Medicinal Chemistry. 103: 252-268. PMID 26363505 DOI: 10.1016/J.Ejmech.2015.08.049  0.317
2015 Noel S, Martina MN, Bandapalle S, Racusen LC, Potteti HR, Hamad AR, Reddy SP, Rabb H. T Lymphocyte-Specific Activation of Nrf2 Protects from AKI. Journal of the American Society of Nephrology : Jasn. PMID 26293820 DOI: 10.1681/Asn.2014100978  0.39
2015 Huang LS, Berdyshev EV, Tran JT, Xie L, Chen J, Ebenezer DL, Mathew B, Gorshkova I, Zhang W, Reddy SP, Harijith A, Wang G, Feghali-Bostwick C, Noth I, Ma SF, et al. Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy. Thorax. PMID 26286721 DOI: 10.1136/Thoraxjnl-2014-206684  0.354
2015 Reddy NM, Potteti HR, Vegiraju S, Chen HJ, Tamatam CM, Reddy SP. PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in Mice. Plos One. 10: e0129676. PMID 26075390 DOI: 10.1371/Journal.Pone.0129676  0.564
2015 Rajasekaran S, Reddy Tamatam C, Reddy Potteti H, Raman V, Lee JW, Matthay MA, Mehta D, Machi Reddy N, Reddy SP. Visualization of Fra-1/AP-1 activation during LPS-induced inflammatory lung injury using fluorescence optical imaging. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00315.2014. PMID 26071555 DOI: 10.1152/Ajplung.00315.2014  0.54
2015 Vaz M, Rajasekaran S, Potteti HR, Reddy SP. Myeloid-specific Fos-related antigen-1 regulates cigarette smoke-induced lung inflammation, not emphysema, in mice. American Journal of Respiratory Cell and Molecular Biology. 53: 125-34. PMID 25489966 DOI: 10.1165/Rcmb.2014-0118Oc  0.51
2015 Reddy NM, Tamatam CR, Reddy SP. Nrf2-Regulated Signaling Is Crucial for Alveolar Macrophage–Mediated Efferocytosis during Hyperoxic Lung Injury and Repair Annals of the American Thoracic Society. 12. DOI: 10.1513/Annalsats.201406-281Mg  0.479
2014 Reddy SP, Natarajan V, Dudek AZ. MARCKS is marked in combating lung cancer growth and acquired resistance. American Journal of Respiratory and Critical Care Medicine. 190: 1084-6. PMID 25398105 DOI: 10.1164/Rccm.201410-1922Ed  0.449
2014 Huang LS, Mathew B, Li H, Zhao Y, Ma SF, Noth I, Reddy SP, Harijith A, Usatyuk PV, Berdyshev EV, Kaminski N, Zhou T, Zhang W, Zhang Y, Rehman J, et al. The mitochondrial cardiolipin remodeling enzyme lysocardiolipin acyltransferase is a novel target in pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 189: 1402-1415. PMID 24779708 DOI: 10.1164/Rccm.201310-1917Oc  0.465
2014 Liu M, Reddy NM, Higbee EM, Potteti HR, Noel S, Racusen L, Kensler TW, Sporn MB, Reddy SP, Rabb H. The Nrf2 triterpenoid activator, CDDO-imidazolide, protects kidneys from ischemia-reperfusion injury in mice. Kidney International. 85: 134-41. PMID 24088953 DOI: 10.1038/Ki.2013.357  0.4
2014 Mittal M, Siddiqui MR, Tran K, Reddy SP, Malik AB. Reactive oxygen species in inflammation and tissue injury. Antioxidants & Redox Signaling. 20: 1126-67. PMID 23991888 DOI: 10.1089/Ars.2012.5149  0.365
2014 Kalakonda S, Nallar SC, Lindner DJ, Sun P, Lorenz RR, Lamarre E, Reddy SP, Kalvakolanu DV. GRIM-19 mutations fail to inhibit v-Src-induced oncogenesis. Oncogene. 33: 3195-204. PMID 23851499 DOI: 10.1038/Onc.2013.271  0.377
2013 Harijith A, Pendyala S, Reddy NM, Bai T, Usatyuk PV, Berdyshev E, Gorshkova I, Huang LS, Mohan V, Garzon S, Kanteti P, Reddy SP, Raj JU, Natarajan V. Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins. The American Journal of Pathology. 183: 1169-82. PMID 23933064 DOI: 10.1016/J.Ajpath.2013.06.018  0.534
2013 Rajasekaran S, Reddy NM, Zhang W, Reddy SP. Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis. Bmc Genomics. 14: 381. PMID 23758685 DOI: 10.1186/1471-2164-14-381  0.482
2013 Potteti HR, Reddy NM, Hei TK, Kalvakolanu DV, Reddy SP. The NRF2 activation and antioxidative response are not impaired overall during hyperoxia-induced lung epithelial cell death. Oxidative Medicine and Cellular Longevity. 2013: 798401. PMID 23738042 DOI: 10.1155/2013/798401  0.495
2013 Mathew B, Jacobson JR, Siegler JH, Moitra J, Blasco M, Xie L, Unzueta C, Zhou T, Evenoski C, Al-Sakka M, Sharma R, Huey B, Bulent A, Smith B, Jayaraman S, ... ... Reddy SP, et al. Role of migratory inhibition factor in age-related susceptibility to radiation lung injury via NF-E2-related factor-2 and antioxidant regulation. American Journal of Respiratory Cell and Molecular Biology. 49: 269-78. PMID 23526214 DOI: 10.1165/Rcmb.2012-0291Oc  0.411
2013 Huang LS, Berdyshev E, Mathew B, Fu P, Gorshkova IA, He D, Ma W, Noth I, Ma SF, Pendyala S, Reddy SP, Zhou T, Zhang W, Garzon SA, Garcia JG, et al. Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1749-60. PMID 23315259 DOI: 10.1096/Fj.12-219634  0.508
2012 Rajasekaran S, Vaz M, Reddy SP. Fra-1/AP-1 transcription factor negatively regulates pulmonary fibrosis in vivo. Plos One. 7: e41611. PMID 22911824 DOI: 10.1371/Journal.Pone.0041611  0.53
2012 D'Alessio FR, Tsushima K, Aggarwal NR, Mock JR, Eto Y, Garibaldi BT, Files DC, Avalos CR, Rodriguez JV, Waickman AT, Reddy SP, Pearse DB, Sidhaye VK, Hassoun PM, Crow MT, et al. Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase Journal of Immunology. 189: 2234-2245. PMID 22844117 DOI: 10.4049/Jimmunol.1102606  0.504
2012 Vaz M, Machireddy N, Irving A, Potteti HR, Chevalier K, Kalvakolanu D, Reddy SP. Oxidant-induced cell death and Nrf2-dependent antioxidative response are controlled by Fra-1/AP-1. Molecular and Cellular Biology. 32: 1694-709. PMID 22393254 DOI: 10.1128/Mcb.06390-11  0.415
2012 Reddy NM, Vegiraju S, Irving A, Paun BC, Luzina IG, Atamas SP, Biswal S, Ana NA, Mitzner W, Reddy SP. Targeted deletion of Jun/AP-1 in alveolar epithelial cells causes progressive emphysema and worsens cigarette smoke-induced lung inflammation. The American Journal of Pathology. 180: 562-74. PMID 22265050 DOI: 10.1016/J.Ajpath.2011.10.029  0.512
2012 Ramchandran R, Pilipenko E, Bach L, Raghavan A, Reddy SP, Raj JU. Hypoxic regulation of pulmonary vascular smooth muscle cyclic guanosine monophosphate-dependent kinase by the ubiquitin conjugating system. American Journal of Respiratory Cell and Molecular Biology. 46: 323-30. PMID 21997485 DOI: 10.1165/Rcmb.2011-0165Oc  0.376
2012 Vaz M, Reddy NM, Rajasekaran S, Reddy SP. Genetic disruption of Fra-1 decreases susceptibility to endotoxin-induced acute lung injury and mortality in mice. American Journal of Respiratory Cell and Molecular Biology. 46: 55-62. PMID 21816965 DOI: 10.1165/Rcmb.2011-0169Oc  0.509
2011 Singh DK, Sarkar J, Raghavan A, Reddy SP, Raj JU. Hypoxia modulates the expression of leucine zipper-positive MYPT1 and its interaction with protein kinase G and Rho kinases in pulmonary arterial smooth muscle cells. Pulmonary Circulation. 1: 487-98. PMID 22530104 DOI: 10.4103/2045-8932.93548  0.35
2011 Nallar SC, Lin L, Srivastava V, Gade P, Hofmann ER, Ahmed H, Reddy SP, Kalvakolanu DV. GRIM-1, a novel growth suppressor, inhibits rRNA maturation by suppressing small nucleolar RNAs. Plos One. 6: e24082. PMID 21931644 DOI: 10.1371/Journal.Pone.0024082  0.336
2011 Kong X, Thimmulappa R, Craciun F, Harvey C, Singh A, Kombairaju P, Reddy SP, Remick D, Biswal S. Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis. American Journal of Respiratory and Critical Care Medicine. 184: 928-38. PMID 21799073 DOI: 10.1164/Rccm.201102-0271Oc  0.38
2011 Reddy NM, Potteti HR, Mariani TJ, Biswal S, Reddy SP. Conditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation. American Journal of Respiratory Cell and Molecular Biology. 45: 1161-8. PMID 21659655 DOI: 10.1165/Rcmb.2011-0144Oc  0.542
2011 Pendyala S, Moitra J, Kalari S, Kleeberger SR, Zhao Y, Reddy SP, Garcia JG, Natarajan V. Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter. Free Radical Biology & Medicine. 50: 1749-59. PMID 21443946 DOI: 10.1016/J.Freeradbiomed.2011.03.022  0.488
2010 Li W, Febbraio M, Reddy SP, Yu DY, Yamamoto M, Silverstein RL. CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs. The Journal of Clinical Investigation. 120: 3996-4006. PMID 20978343 DOI: 10.1172/Jci42823  0.351
2010 Sun P, Nallar SC, Raha A, Kalakonda S, Velalar CN, Reddy SP, Kalvakolanu DV. GRIM-19 and p16(INK4a) synergistically regulate cell cycle progression and E2F1-responsive gene expression. The Journal of Biological Chemistry. 285: 27545-52. PMID 20522552 DOI: 10.1074/Jbc.M110.105767  0.348
2010 Cho HY, Gladwell W, Wang X, Chorley B, Bell D, Reddy SP, Kleeberger SR. Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice. American Journal of Respiratory and Critical Care Medicine. 182: 170-82. PMID 20224069 DOI: 10.1164/Rccm.200907-1047Oc  0.551
2010 Uno K, Prow TW, Bhutto IA, Yerrapureddy A, McLeod DS, Yamamoto M, Reddy SP, Lutty GA. Role of Nrf2 in retinal vascular development and the vaso-obliterative phase of oxygen-induced retinopathy. Experimental Eye Research. 90: 493-500. PMID 20064509 DOI: 10.1016/J.Exer.2009.12.012  0.344
2010 Bauer AK, Travis EL, Malhotra SS, Rondini EA, Walker C, Cho HY, Trivedi S, Gladwell W, Reddy S, Kleeberger SR. Identification of novel susceptibility genes in ozone-induced inflammation in mice. The European Respiratory Journal. 36: 428-37. PMID 20032013 DOI: 10.1183/09031936.00145309  0.35
2010 Vaz M, Reddy NM, Wagner EF, Reddy SP. Abstract 1587: Targeted deletion of Fra-1 blocks oncogenic K-ras induced lung tumor development and progression in mice Cancer Research. 70: 1587-1587. DOI: 10.1158/1538-7445.Am10-1587  0.392
2009 Reddy NM, Suryanarayana V, Kalvakolanu DV, Yamamoto M, Kensler TW, Hassoun PM, Kleeberger SR, Reddy SP. Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 183: 4601-8. PMID 19734219 DOI: 10.4049/Jimmunol.0901754  0.506
2009 Reddy NM, Suryanaraya V, Yates MS, Kleeberger SR, Hassoun PM, Yamamoto M, Liby KT, Sporn MB, Kensler TW, Reddy SP. The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice. American Journal of Respiratory and Critical Care Medicine. 180: 867-74. PMID 19679692 DOI: 10.1164/Rccm.200905-0670Oc  0.504
2009 Gade P, Singh AK, Roy SK, Reddy SP, Kalvakolanu DV. Down-regulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of metastasis-associated dapk1 in human cancers and cancer cells. International Journal of Cancer. Journal International Du Cancer. 125: 1566-74. PMID 19521987 DOI: 10.1002/Ijc.24493  0.39
2009 Reddy NM, Kleeberger SR, Kensler TW, Yamamoto M, Hassoun PM, Reddy SP. Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice. Journal of Immunology (Baltimore, Md. : 1950). 182: 7264-71. PMID 19454723 DOI: 10.4049/Jimmunol.0804248  0.539
2009 Liu M, Grigoryev DN, Crow MT, Haas M, Yamamoto M, Reddy SP, Rabb H. Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice. Kidney International. 76: 277-85. PMID 19436334 DOI: 10.1038/Ki.2009.157  0.421
2009 Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla M, Hasan E, Pearse DB, Reddy SP, Grigoryev DN, Cheadle C, Esmon CT, Garcia JG, Hassoun PM. Activated protein C protects against ventilator-induced pulmonary capillary leak. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L1002-11. PMID 19363121 DOI: 10.1152/Ajplung.90555.2008  0.452
2009 Damarla M, Hasan E, Boueiz A, Le A, Pae HH, Montouchet C, Kolb T, Simms T, Myers A, Kayyali US, Gaestel M, Peng X, Reddy SP, Damico R, Hassoun PM. Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury. Plos One. 4: e4600. PMID 19240800 DOI: 10.1371/Journal.Pone.0004600  0.491
2008 Bierman A, Yerrapureddy A, Reddy NM, Hassoun PM, Reddy SP. Epidermal growth factor receptor (EGFR) regulates mechanical ventilation-induced lung injury in mice. Translational Research : the Journal of Laboratory and Clinical Medicine. 152: 265-72. PMID 19059161 DOI: 10.1016/J.Trsl.2008.10.004  0.719
2008 Reddy SP. The antioxidant response element and oxidative stress modifiers in airway diseases. Current Molecular Medicine. 8: 376-83. PMID 18691064 DOI: 10.2174/156652408785160925  0.398
2008 Le A, Damico R, Damarla M, Boueiz A, Pae HH, Skirball J, Hasan E, Peng X, Chesley A, Crow MT, Reddy SP, Tuder RM, Hassoun PM. Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 1282-90. PMID 18669934 DOI: 10.1152/Japplphysiol.90689.2008  0.44
2008 Adiseshaiah P, Li J, Vaz M, Kalvakolanu DV, Reddy SP. ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter. Biochemical and Biophysical Research Communications. 371: 304-8. PMID 18435914 DOI: 10.1016/J.Bbrc.2008.04.063  0.413
2008 Li H, Gade P, Nallar SC, Raha A, Roy SK, Karra S, Reddy JK, Reddy SP, Kalvakolanu DV. The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma. The Journal of Biological Chemistry. 283: 13077-86. PMID 18339625 DOI: 10.1074/Jbc.M800604200  0.346
2008 Adiseshaiah P, Vaz M, Machireddy N, Kalvakolanu DV, Reddy SP. A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion. Journal of Cellular Physiology. 216: 405-12. PMID 18288638 DOI: 10.1002/Jcp.21410  0.402
2008 Theodore M, Kawai Y, Yang J, Kleshchenko Y, Reddy SP, Villalta F, Arinze IJ. Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2. The Journal of Biological Chemistry. 283: 8984-94. PMID 18238777 DOI: 10.1074/Jbc.M709040200  0.371
2007 Papaiahgari S, Yerrapureddy A, Reddy SR, Reddy NM, Dodd-O JM, Crow MT, Grigoryev DN, Barnes K, Tuder RM, Yamamoto M, Kensler TW, Biswal S, Mitzner W, Hassoun PM, Reddy SP. Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice. American Journal of Respiratory and Critical Care Medicine. 176: 1222-35. PMID 17901416 DOI: 10.1164/Rccm.200701-060Oc  0.485
2007 Reddy NM, Kleeberger SR, Yamamoto M, Kensler TW, Scollick C, Biswal S, Reddy SP. Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection. Physiological Genomics. 32: 74-81. PMID 17895394 DOI: 10.1152/Physiolgenomics.00126.2007  0.482
2007 Kalakonda S, Nallar SC, Gong P, Lindner DJ, Goldblum SE, Reddy SP, Kalvakolanu DV. Tumor suppressive protein gene associated with retinoid-interferon-induced mortality (GRIM)-19 inhibits src-induced oncogenic transformation at multiple levels. The American Journal of Pathology. 171: 1352-68. PMID 17823279 DOI: 10.2353/Ajpath.2007.070241  0.407
2007 Reddy SP, Hassoun PM, Brower R. Redox imbalance and ventilator-induced lung injury. Antioxidants & Redox Signaling. 9: 2003-12. PMID 17822361 DOI: 10.1089/Ars.2007.1770  0.476
2007 Kalakonda S, Nallar SC, Lindner DJ, Hu J, Reddy SP, Kalvakolanu DV. Tumor-suppressive activity of the cell death activator GRIM-19 on a constitutively active signal transducer and activator of transcription 3. Cancer Research. 67: 6212-20. PMID 17616678 DOI: 10.1158/0008-5472.Can-07-0031  0.43
2007 Adiseshaiah P, Lindner DJ, Kalvakolanu DV, Reddy SP. FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo. Cancer Research. 67: 6204-11. PMID 17616677 DOI: 10.1158/0008-5472.Can-06-4687  0.44
2007 Reddy NM, Kleeberger SR, Cho HY, Yamamoto M, Kensler TW, Biswal S, Reddy SP. Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants. American Journal of Respiratory Cell and Molecular Biology. 37: 3-8. PMID 17413030 DOI: 10.1165/Rcmb.2007-0004Rc  0.485
2007 Marzec JM, Christie JD, Reddy SP, Jedlicka AE, Vuong H, Lanken PN, Aplenc R, Yamamoto T, Yamamoto M, Cho HY, Kleeberger SR. Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2237-46. PMID 17384144 DOI: 10.1096/Fj.06-7759Com  0.428
2007 Ma X, Kalakonda S, Srinivasula SM, Reddy SP, Platanias LC, Kalvakolanu DV. GRIM-19 associates with the serine protease HtrA2 for promoting cell death Oncogene. 26: 4842-4849. PMID 17297443 DOI: 10.1038/Sj.Onc.1210287  0.327
2007 Yuan-Chen Wu D, Wu R, Reddy SP, Lee YC, Chang MM. Distinctive epidermal growth factor receptor/extracellular regulated kinase-independent and -dependent signaling pathways in the induction of airway mucin 5B and mucin 5AC expression by phorbol 12-myristate 13-acetate. The American Journal of Pathology. 170: 20-32. PMID 17200179 DOI: 10.2353/Ajpath.2007.060452  0.443
2007 Papaiahgari S, Yerrapureddy A, Hassoun PM, Garcia JG, Birukov KG, Reddy SP. EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation. American Journal of Respiratory Cell and Molecular Biology. 36: 304-12. PMID 17008637 DOI: 10.1165/Rcmb.2006-0131Oc  0.527
2007 Wu DYC, Wu R, Reddy SP, Lee YC, Chang MMJ. Distinctive signaling pathways in the induction of airway MUC5B and -AC expression by phorbol 12-myristate 13-acetate and their implication in lung diseases Journal of Organ Dysfunction. 3: 100-103. DOI: 10.1080/17471060601152364  0.473
2006 Adiseshaiah P, Kalvakolanu DV, Reddy SP. A JNK-independent signaling pathway regulates TNF alpha-stimulated, c-Jun-driven FRA-1 protooncogene transcription in pulmonary epithelial cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 7193-202. PMID 17082637 DOI: 10.4049/Jimmunol.177.10.7193  0.383
2006 Alchanati I, Nallar SC, Sun P, Gao L, Hu J, Stein A, Yakirevich E, Konforty D, Alroy I, Zhao X, Reddy SP, Resnick MB, Kalvakolanu DV. A proteomic analysis reveals the loss of expression of the cell death regulatory gene GRIM-19 in human renal cell carcinomas Oncogene. 25: 7138-7147. PMID 16732315 DOI: 10.1038/Sj.Onc.1209708  0.391
2006 Abdulnour RE, Peng X, Finigan JH, Han EJ, Hasan EJ, Birukov KG, Reddy SP, Watkins JE, Kayyali US, Garcia JG, Tuder RM, Hassoun PM. Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L345-53. PMID 16632522 DOI: 10.1152/Ajplung.00453.2005  0.479
2006 Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. The Journal of Clinical Investigation. 116: 984-95. PMID 16585964 DOI: 10.1172/Jci25790  0.432
2006 Zhang Q, Adiseshaiah P, Kalvakolanu DV, Reddy SP. A Phosphatidylinositol 3-kinase-regulated Akt-independent signaling promotes cigarette smoke-induced FRA-1 expression. The Journal of Biological Chemistry. 281: 10174-81. PMID 16490785 DOI: 10.1074/Jbc.M513008200  0.424
2006 Cho HY, Reddy SP, Kleeberger SR. Nrf2 defends the lung from oxidative stress. Antioxidants & Redox Signaling. 8: 76-87. PMID 16487040 DOI: 10.1089/Ars.2006.8.76  0.489
2006 Papaiahgari S, Zhang Q, Kleeberger SR, Cho HY, Reddy SP. Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-PI3K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells. Antioxidants & Redox Signaling. 8: 43-52. PMID 16487036 DOI: 10.1089/Ars.2006.8.43  0.443
2006 Mossman BT, Lounsbury KM, Reddy SP. Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. American Journal of Respiratory Cell and Molecular Biology. 34: 666-9. PMID 16484683 DOI: 10.1165/Rcmb.2006-0047Sf  0.504
2005 Roy SK, Hu J, Meng Q, Hu J, Reddy SP, Kalvakolanu DV. Development of monoclonal antibodies against GBF1 and their use in studying its functions. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 25: 666-73. PMID 16318580 DOI: 10.1089/Jir.2005.25.666  0.325
2005 Wang L, Devarajan E, He J, Reddy SP, Dai JL. Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression. Cancer Research. 65: 10289-97. PMID 16288017 DOI: 10.1158/0008-5472.Can-05-2231  0.32
2005 Adiseshaiah P, Peddakama S, Zhang Q, Kalvakolanu DV, Reddy SP. Mitogen regulated induction of FRA-1 proto-oncogene is controlled by the transcription factors binding to both serum and TPA response elements. Oncogene. 24: 4193-205. PMID 15806162 DOI: 10.1038/Sj.Onc.1208583  0.379
2005 Cho HY, Reddy SP, Debiase A, Yamamoto M, Kleeberger SR. Gene expression profiling of NRF2-mediated protection against oxidative injury. Free Radical Biology & Medicine. 38: 325-43. PMID 15629862 DOI: 10.1016/J.Freeradbiomed.2004.10.013  0.453
2005 Zhang Q, Adiseshaiah P, Reddy SP. Matrix metalloproteinase/epidermal growth factor receptor/mitogen-activated protein kinase signaling regulate fra-1 induction by cigarette smoke in lung epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 32: 72-81. PMID 15528491 DOI: 10.1165/Rcmb.2004-0198Oc  0.445
2004 Papaiahgari S, Kleeberger SR, Cho HY, Kalvakolanu DV, Reddy SP. NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells. The Journal of Biological Chemistry. 279: 42302-12. PMID 15292179 DOI: 10.1074/Jbc.M408275200  0.519
2004 Cho HY, Reddy SP, Yamamoto M, Kleeberger SR. The transcription factor NRF2 protects against pulmonary fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1258-60. PMID 15208274 DOI: 10.1096/Fj.03-1127Fje  0.424
2004 Zhang Q, Kleeberger SR, Reddy SP. DEP-induced fra-1 expression correlates with a distinct activation of AP-1-dependent gene transcription in the lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L427-36. PMID 14565943 DOI: 10.1152/Ajplung.00221.2003  0.471
2003 Wagner EM, Gallagher SJ, Reddy S, Mitzner W. Effects of tamoxifen on ischemia-induced angiogenesis in the mouse lung. Angiogenesis. 6: 65-71. PMID 14517406 DOI: 10.1023/A:1025822127847  0.399
2002 Reddy SP, Mossman BT. Role and regulation of activator protein-1 in toxicant-induced responses of the lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L1161-78. PMID 12424143 DOI: 10.1152/ajplung.00140.2002  0.427
2002 Reddy SP, Adiseshaiah P, Shapiro P, Vuong H. BMK1 (ERK5) regulates squamous differentiation marker SPRR1B transcription in Clara-like H441 cells. American Journal of Respiratory Cell and Molecular Biology. 27: 64-70. PMID 12091247 DOI: 10.1165/ajrcmb.27.1.20020003oc  0.313
2002 Cho HY, Jedlicka AE, Reddy SP, Kensler TW, Yamamoto M, Zhang LY, Kleeberger SR. Role of NRF2 in protection against hyperoxic lung injury in mice. American Journal of Respiratory Cell and Molecular Biology. 26: 175-82. PMID 11804867 DOI: 10.1165/Ajrcmb.26.2.4501  0.415
2002 Cho HY, Jedlicka AE, Reddy SP, Zhang LY, Kensler TW, Kleeberger SR. Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene. American Journal of Respiratory Cell and Molecular Biology. 26: 42-51. PMID 11751202 DOI: 10.1165/Ajrcmb.26.1.4536  0.394
2000 Kleeberger SR, Reddy S, Zhang LY, Jedlicka AE. Genetic susceptibility to ozone-induced lung hyperpermeability: role of toll-like receptor 4. American Journal of Respiratory Cell and Molecular Biology. 22: 620-627. PMID 10783135 DOI: 10.1165/Ajrcmb.22.5.3912  0.33
2000 Lau D, Xue L, Hu R, Liaw T, Wu R, Reddy S. Expression and regulation of a molecular marker, SPR1, in multistep bronchial carcinogenesis. American Journal of Respiratory Cell and Molecular Biology. 22: 92-6. PMID 10615070 DOI: 10.1165/Ajrcmb.22.1.3637  0.357
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