| Year |
Citation |
Score |
| 2015 |
Kehrer JP, Klotz LO. Free radicals and related reactive species as mediators of tissue injury and disease: implications for Health. Critical Reviews in Toxicology. 45: 765-98. PMID 26610815 DOI: 10.3109/10408444.2015.1074159 |
0.31 |
|
| 2010 |
Kehrer JP. Lipocalin-2: pro- or anti-apoptotic? Cell Biology and Toxicology. 26: 83-9. PMID 19160065 DOI: 10.1007/S10565-009-9119-9 |
0.374 |
|
| 2006 |
Deshpande VS, Kehrer JP. Mechanisms of N-acetylcysteine-driven enhancement of MK886-induced apoptosis. Cell Biology and Toxicology. 22: 303-11. PMID 16817014 DOI: 10.1007/S10565-006-0072-6 |
0.413 |
|
| 2006 |
Tong Z, Wu X, Chen CS, Kehrer JP. Cytotoxicity of a non-cyclooxygenase-2 inhibitory derivative of celecoxib in non-small-cell lung cancer A549 cells. Lung Cancer (Amsterdam, Netherlands). 52: 117-24. PMID 16497409 DOI: 10.1016/J.Lungcan.2005.12.003 |
0.39 |
|
| 2006 |
Deshpande VS, Kehrer JP. Oxidative stress-driven mechanisms of nordihydroguaiaretic acid-induced apoptosis in FL5.12 cells. Toxicology and Applied Pharmacology. 214: 230-6. PMID 16473382 DOI: 10.1016/J.Taap.2005.12.011 |
0.387 |
|
| 2005 |
Tong Z, Wu X, Ovcharenko D, Zhu J, Chen CS, Kehrer JP. Neutrophil gelatinase-associated lipocalin as a survival factor. The Biochemical Journal. 391: 441-8. PMID 16060857 DOI: 10.1042/Bj20051020 |
0.392 |
|
| 2005 |
Kern JC, Kehrer JP. Free radicals and apoptosis: relationships with glutathione, thioredoxin, and the BCL family of proteins. Frontiers in Bioscience : a Journal and Virtual Library. 10: 1727-38. PMID 15769662 DOI: 10.2741/1656 |
0.683 |
|
| 2004 |
Yang X, Wu X, Choi YE, Kern JC, Kehrer JP. Effect of acrolein and glutathione depleting agents on thioredoxin. Toxicology. 204: 209-18. PMID 15388247 DOI: 10.1016/J.Tox.2004.06.056 |
0.663 |
|
| 2004 |
Atarod EB, Kehrer JP. Dissociation of oxidant production by peroxisome proliferator-activated receptor ligands from cell death in human cell lines. Free Radical Biology & Medicine. 37: 36-47. PMID 15183193 DOI: 10.1016/J.Freeradbiomed.2004.04.015 |
0.386 |
|
| 2004 |
Watson WH, Yang X, Choi YE, Jones DP, Kehrer JP. Thioredoxin and its role in toxicology. Toxicological Sciences : An Official Journal of the Society of Toxicology. 78: 3-14. PMID 14691207 DOI: 10.1093/Toxsci/Kfh050 |
0.369 |
|
| 2003 |
Wu X, Biswal SS, Kehrer JP. Roles of 5-lipoxygenase activating protein in cell proliferation and apoptosis Cell Biology and Toxicology. 19: 135-143. PMID 12945742 DOI: 10.1023/A:1024789810277 |
0.37 |
|
| 2003 |
Biswal S, Maxwell T, Rangasamy T, Kehrer JP. Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein. Carcinogenesis. 24: 1401-6. PMID 12807757 DOI: 10.1093/Carcin/Bgg061 |
0.3 |
|
| 2003 |
Tong Z, Wu X, Kehrer JP. Increased expression of the lipocalin 24p3 as an apoptotic mechanism for MK886. The Biochemical Journal. 372: 203-10. PMID 12614196 DOI: 10.1042/Bj20021696 |
0.374 |
|
| 2003 |
La E, Kern JC, Atarod EB, Kehrer JP. Fatty acid release and oxidation are factors in lipoxygenase inhibitor-induced apoptosis. Toxicology Letters. 138: 193-203. PMID 12565196 DOI: 10.1016/S0378-4274(02)00407-1 |
0.683 |
|
| 2002 |
Thuillier P, Brash AR, Kehrer JP, Stimmel JB, Leesnitzer LM, Yang P, Newman RA, Fischer SM. Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors. The Biochemical Journal. 366: 901-10. PMID 12069687 DOI: 10.1042/Bj20020377 |
0.309 |
|
| 2002 |
Tang DG, La E, Kern J, Kehrer JP. Fatty acid oxidation and signaling in apoptosis. Biological Chemistry. 383: 425-42. PMID 12033433 DOI: 10.1515/Bc.2002.046 |
0.677 |
|
| 2002 |
Biswal S, Acquaah-Mensah G, Datta K, Wu X, Kehrer JP. Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications. Chemical Research in Toxicology. 15: 180-6. PMID 11849044 DOI: 10.1021/Tx015552P |
0.372 |
|
| 2002 |
Kern JC, Kehrer JP. Acrolein-induced cell death: a caspase-influenced decision between apoptosis and oncosis/necrosis. Chemico-Biological Interactions. 139: 79-95. PMID 11803030 DOI: 10.1016/S0009-2797(01)00295-2 |
0.675 |
|
| 2001 |
Datta K, Kern JC, Biswal SS, Kehrer JP. Proteolytic loss of bcl-x(L) in FL5.12 Cells undergoing apoptosis induced by MK886. Toxicology and Applied Pharmacology. 174: 273-81. PMID 11485388 DOI: 10.1006/Taap.2001.9220 |
0.679 |
|
| 2001 |
Kehrer JP, Biswal SS, La E, Thuillier P, Datta K, Fischer SM, Vanden Heuvel JP. Inhibition of peroxisome-proliferator-activated receptor (PPAR)α by MK886 Biochemical Journal. 356: 899-906. PMID 11389700 DOI: 10.1042/0264-6021:3560899 |
0.398 |
|
| 2001 |
Biswal SS, Datta K, Kehrer JP. Association between bcl-xL and 5-lipoxygenase activating protein (FLAP) levels in IL-3-dependent FL5.12 cells Toxicology. 160: 97-103. PMID 11246129 DOI: 10.1016/S0300-483X(00)00442-X |
0.37 |
|
| 2000 |
Biswal SS, Datta K, Acquaah-Mensah GK, Kehrer JP. Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells. Toxicology. 154: 45-53. PMID 11118669 DOI: 10.1016/S0300-483X(00)00296-1 |
0.428 |
|
| 2000 |
Kehrer JP. Cause-effect of oxidative stress and apoptosis Teratology. 62: 235-236. PMID 10992267 DOI: 10.1002/1096-9926(200010)62:4<235::Aid-Tera11>3.0.Co;2-3 |
0.317 |
|
| 2000 |
Kehrer JP, Biswal SS. The molecular effects of acrolein Toxicological Sciences. 57: 6-15. PMID 10966506 DOI: 10.1093/Toxsci/57.1.6 |
0.359 |
|
| 2000 |
Biswal SS, Datta K, Shaw SD, Feng X, Robertson JD, Kehrer JP. Glutathione oxidation and mitochondrial depolarization as mechanisms of nordihydroguaiaretic acid-induced apoptosis in lipoxygenase-deficient FL5.12 Cells Toxicological Sciences. 53: 77-83. PMID 10653524 DOI: 10.1093/Toxsci/53.1.77 |
0.44 |
|
| 1999 |
Robertson JD, Datta K, Biswal SS, Kehrer JP. Heat-shock protein 70 antisense oligomers enhance proteasome inhibitor-induced apoptosis Biochemical Journal. 344: 477-485. PMID 10567231 DOI: 10.1042/Bj3440477 |
0.372 |
|
| 1999 |
Datta K, Biswal SS, Kehrer JP. The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP Biochemical Journal. 340: 371-375. PMID 10333477 DOI: 10.1042/0264-6021:3400371 |
0.421 |
|
| 1999 |
Bojes HK, Feng X, Kehrer JP, Cohen GM. Apoptosis in hematopoietic cells (FL5.12) caused by interleukin-3 withdrawal: Relationship to caspase activity and the loss of glutathione Cell Death and Differentiation. 6: 61-70. PMID 10200549 DOI: 10.1038/Sj.Cdd.4400452 |
0.357 |
|
| 1999 |
Horton ND, Biswal SS, Corrigan LL, Bratta J, Kehrer JP. Acrolein causes inhibitor κb-independent decreases in nuclear factor κB activation in human lung adenocarcinoma (A549) cells Journal of Biological Chemistry. 274: 9200-9206. PMID 10092592 DOI: 10.1074/Jbc.274.14.9200 |
0.317 |
|
| 1998 |
Datta K, Biswal SS, Xu J, Towndrow KM, Feng X, Kehrer JP. A relationship between 5-lipoxygenase-activating protein and bcl-x(L) expression in murine pro-B lymphocytic FL5.12 cells Journal of Biological Chemistry. 273: 28163-28169. PMID 9774436 DOI: 10.1074/Jbc.273.43.28163 |
0.371 |
|
| 1998 |
Datta K, Chin A, Ahmed T, Qing WG, Powell KL, Simhambhatla P, MacLeod MC, Stoica G, Kehrer JP. Mixed effects of 2,6-dithiopurine against cyclophosphamide mediated bladder and lung toxicity in mice Toxicology. 125: 1-11. PMID 9585095 DOI: 10.1016/S0300-483X(97)00149-2 |
0.347 |
|
| 1998 |
Bojes HK, Suresh PK, Mills EM, Spitz DR, Sim JE, Kehrer JP. Bcl-2 and Bcl-x(L) in peroxide-resistant A549 and U87MG cells Toxicological Sciences. 42: 109-116. PMID 9579023 DOI: 10.1006/Toxs.1997.2416 |
0.36 |
|
| 1997 |
Robertson JD, Datta K, Kehrer JP. Bcl-x(L) overexpression restricts heat-induced apoptosis and influences hsp70, bcl-2, and bax protein levels in FL5.12 cells Biochemical and Biophysical Research Communications. 241: 164-168. PMID 9405251 DOI: 10.1006/Bbrc.1997.7782 |
0.333 |
|
| 1997 |
Horton ND, Mamiya BM, Kehrer JP. Relationships between cell density, glutathione and proliferation of A549 human lung adenocarcinoma cells treated with acrolein Toxicology. 122: 111-122. PMID 9274807 DOI: 10.1016/S0300-483X(97)00086-3 |
0.355 |
|
| 1997 |
Bojes HK, Datta K, Xu J, Chin A, Simonian P, Nuñez G, Kehrer JP. Bcl-xL overexpression attenuates glutathione depletion in FL5.12 cells following interleukin-3 withdrawal The Biochemical Journal. 325. PMID 9230108 DOI: 10.1042/Bj3250315 |
0.41 |
|
| 1996 |
Ramu K, Perry CS, Ahmed T, Pakenham G, Kehrer JP. Studies on the basis for the toxicity of acrolein mercapturates. Toxicology and Applied Pharmacology. 140: 487-98. PMID 8887466 DOI: 10.1006/Taap.1996.0245 |
0.381 |
|
| 1996 |
Liu H, Kehrer JP. The reduction of glutathione disulfide produced by t-butyl hydroperoxide in respiring mitochondria Free Radical Biology and Medicine. 20: 433-442. PMID 8720915 DOI: 10.1016/0891-5849(95)02093-4 |
0.306 |
|
| 1995 |
Stevenson DE, Kehrer JP, Kolaja KL, Walborg EF, Klaunig JE. Effect of dietary antioxidants on dieldrin-induced hepatotoxicity in mice. Toxicology Letters. 75: 177-83. PMID 7863524 DOI: 10.1016/0378-4274(94)03178-A |
0.311 |
|
| 1995 |
Perry CS, Liu X, Lund LG, Whitman CP, Kehrer JP. Differential toxicities of cyclophosphamide and its glutathione metabolites to A549 cells Toxicology in Vitro. 9: 21-26. DOI: 10.1016/0887-2333(94)00187-Y |
0.34 |
|
| 1994 |
Kehrer JP, Lund LG. Cellular reducing equivalents and oxidative stress Free Radical Biology and Medicine. 17: 65-75. PMID 7959167 DOI: 10.1016/0891-5849(94)90008-6 |
0.339 |
|
| 1993 |
Frasier L, Kehrer JP. Effect of indomethacin, aspirin, nordihydroguairetic acid, and piperonyl butoxide on cyclophosphamide-induced bladder damage Drug and Chemical Toxicology. 16: 117-133. PMID 8486095 DOI: 10.3109/01480549309031992 |
0.361 |
|
| 1992 |
Palamanda JR, Kehrer JP. Inhibition of protein carbonyl formation and lipid peroxidation by glutathione in rat liver microsomes Archives of Biochemistry and Biophysics. 293: 103-109. PMID 1731626 DOI: 10.1016/0003-9861(92)90371-3 |
0.348 |
|
| 1992 |
Kehrer JP, Paraidathathu T. The use of fluorescent probes to assess oxidative processes in isolated-perfused rat heart tissue Free Radical Research. 16: 217-225. PMID 1505782 DOI: 10.3109/10715769209049175 |
0.301 |
|
| 1992 |
Spitz DR, Kinter MT, Kehrer JP, Roberts RJ. The effect of monosaturated and polyunsaturated fatty acids on oxygen toxicity in cultured cells Pediatric Research. 32: 366-372. PMID 1408477 DOI: 10.1203/00006450-199209000-00024 |
0.322 |
|
| 1991 |
Park Y, Kanekal S, Kehrer JP. Oxidative changes in hypoxic rat heart tissue American Journal of Physiology - Heart and Circulatory Physiology. 260. PMID 2035661 DOI: 10.1152/Ajpheart.1991.260.5.H1395 |
0.331 |
|
| 1989 |
Murphy ME, Kehrer JP. Oxidative stress and muscular dystrophy Chemico-Biological Interactions. 69: 101-173. PMID 2649259 DOI: 10.1016/0009-2797(89)90075-6 |
0.301 |
|
| 1989 |
Kehrer JP. Bleomycin and cyclophosphamide toxicity in mice with damaged lung tissue Toxicology. 57: 69-82. PMID 2473544 DOI: 10.1016/0300-483X(89)90035-8 |
0.31 |
|
| 1988 |
Park Y, Smith RD, Combs AB, Kehrer JP. Prevention of acetaminophen-induced hepatotoxicity by dimethyl sulfoxide Toxicology. 52: 165-175. PMID 3188030 DOI: 10.1016/0300-483X(88)90202-8 |
0.356 |
|
| 1987 |
Kehrer JP, Lee YCC. Pulmonary hydroxyproline content and production following treatment of mice with O,S,S-trimethyl phosphorodithioate Toxicology Letters. 38: 321-327. PMID 3660435 DOI: 10.1016/0378-4274(87)90015-4 |
0.32 |
|
| 1986 |
Kehrer JP, Lee YCC, Solem SM. Comparison of in vitro and in vivo rates of collagen synthesis in normal and damaged lung tissue Experimental Lung Research. 10: 187-201. PMID 3956448 DOI: 10.3109/01902148609061492 |
0.309 |
|
| 1986 |
Murphy ME, Kehrer JP. Activities of antioxidant enzymes in muscle, liver and lung of chickens with inherited muscular dystrophy. Biochemical and Biophysical Research Communications. 134: 550-6. PMID 3947339 DOI: 10.1016/S0006-291X(86)80455-7 |
0.303 |
|
| 1986 |
Kehrer JP, Klein-Szanto AJP, Thurston DE, Lindenschmidt RC, Witschi HR. O,S,S,-Trimethyl phosphorodithioate-induced lung damage in rats and mice Toxicology and Applied Pharmacology. 84: 480-492. PMID 3726871 DOI: 10.1016/0041-008X(86)90253-X |
0.35 |
|
| 1986 |
Murphy ME, Kehrer JP. Free radicals: a potential pathogenic mechanism in inherited muscular dystrophy. Life Sciences. 39: 2271-8. PMID 3540502 DOI: 10.1016/0024-3205(86)90657-0 |
0.302 |
|
| 1985 |
Lee YCC, Kehrer JP. Increased pulmonary collagen synthesis in mice treated with cyclophosphamide Drug and Chemical Toxicology. 8: 503-512. PMID 4092621 DOI: 10.3109/01480548509041073 |
0.307 |
|
| 1985 |
Kehrer JP. Collagen synthesis and degradation in acutely damaged mouse lung tissue following treatment with prednisolone Biochemical Pharmacology. 34: 2519-2524. PMID 4015692 DOI: 10.1016/0006-2952(85)90536-2 |
0.306 |
|
| 1984 |
Kehrer JP, Paraidathathu T. Enhanced oxygen toxicity following treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea Fundamental and Applied Toxicology. 4: 760-767. PMID 6510607 DOI: 10.1016/0272-0590(84)90097-6 |
0.337 |
|
| 1984 |
Kehrer JP, Klein-Szanto AJ, Sorensen EM, Pearlman R, Rosner MH. Enhanced acute lung damage following corticosteroid treatment. The American Review of Respiratory Disease. 130: 256-61. PMID 6465679 DOI: 10.1164/Arrd.1984.130.2.256 |
0.301 |
|
| 1983 |
Kehrer JP. The effect of bcnu (carmustine) on tissue glutathione reductase activity Toxicology Letters. 17: 63-68. PMID 6623510 DOI: 10.1016/0378-4274(83)90036-X |
0.345 |
|
| 1982 |
Kehrer JP. Collagen production rates following acute lung damage induced by butylated hydroxytoluene Biochemical Pharmacology. 31: 2053-2058. PMID 7115425 DOI: 10.1016/0006-2952(82)90420-8 |
0.314 |
|
| 1977 |
Kehrer JP, Autor AP. Changes in the fatty acid composition of rat lung lipids during development and following age-dependent lipid peroxidation Lipids. 12: 596-603. PMID 895408 DOI: 10.1007/Bf02533388 |
0.307 |
|
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