Stephen R. Ikeda, MD, PhD - Related publications

Affiliations: 
National Institutes of Health, Bethesda, MD 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Vickstrom CR, Liu X, Zhang Y, Mu L, Kelly TJ, Yan X, Hu MM, Snarrenberg ST, Liu QS. T-type calcium channels contribute to burst firing in a subpopulation of medial habenula neurons. Eneuro. PMID 32719103 DOI: 10.1523/ENEURO.0201-20.2020   
2020 Cardoso FC, Marliac MA, Geoffroy C, Schmit M, Bispat A, Lewis RJ, Tuck KL, Duggan PJ. The neuronal calcium ion channel activity of constrained analogues of MONIRO-1. Bioorganic & Medicinal Chemistry. 28: 115655. PMID 32828422 DOI: 10.1016/j.bmc.2020.115655   
2020 Sato A, Arichi S, Kojima F, Hayashi T, Ohba T, Cheung DL, Eto K, Narushima M, Murakoshi H, Maruo Y, Kadoya Y, Nabekura J, Ishibashi H. Histamine depolarizes rat intracardiac ganglion neurons through the activation of TRPC non-selective cation channels. European Journal of Pharmacology. 886: 173536. PMID 32896550 DOI: 10.1016/j.ejphar.2020.173536   
2020 Frankel EB, Kurshan PT. All Talk, No Assembly: Voltage-Gated Calcium Channels Do Not Mediate Active Zone Formation. Neuron. 107: 593-594. PMID 32818471 DOI: 10.1016/j.neuron.2020.07.028   
2020 Guan W, Stephens RF, Mourad O, Mehta A, Fux J, Spafford JD. Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca3 T-type channels alter the passage and block of monovalent and divalent ions. Scientific Reports. 10: 12404. PMID 32710088 DOI: 10.1038/s41598-020-69197-3   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Montandon GG, Cassoli JS, Peigneur S, Braga TV, Moreira Dos Santos D, Bittencourt Paiva AL, Ricardo de Moraes É, Kushmerick C, Borges MH, Richardson M, Monteiro de Castro Pimenta A, Kjeldsen F, Vasconcelos Diniz MR, Tytgat J, Elena de Lima M. GiTx1(β/κ-theraphotoxin-Gi1a), a novel toxin from the venom of Brazilian tarantula Grammostola iheringi (Mygalomorphae, Theraphosidae): Isolation, structural assessments and activity on voltage-gated ion channels. Biochimie. PMID 32717411 DOI: 10.1016/j.biochi.2020.07.008   
2020 Kim JM, Song KS, Xu B, Wang T. Role of potassium channels in female reproductive system. Obstetrics & Gynecology Science. PMID 32838485 DOI: 10.5468/ogs.20064   
2020 Lei J, Liu X, Song M, Zhou Y, Fan J, Shen X, Xu X, Kapoor I, Zhu G, Wang J. Aberrant Exon 8/8a Splicing by Downregulated PTBP (Polypyrimidine Tract-Binding Protein)-1 Increases Ca1.2 Dihydropyridine Resistance to Attenuate Vasodilation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315010. PMID 32787518 DOI: 10.1161/ATVBAHA.120.315010   
2020 Diniz AFA, Ferreira RC, de Souza ILL, da Silva BA. Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review. Frontiers in Pharmacology. 11: 1120. PMID 32848741 DOI: 10.3389/fphar.2020.01120   
2020 Bai JP, Xue N, Lawal O, Nyati A, Santos-Sacchi J, Navaratnam D. Calcium-induced calcium release in proximity to hair cell BK channels revealed by PKA activation. Physiological Reports. 8: e14449. PMID 32748549 DOI: 10.14814/phy2.14449   
2020 Hung TY, Huang CW, Wu SN. High ability of zileuton ((±)-1-(1-benzo[b]thien-2-ylethyl)-1-hydroxyurea) to stimulate I but suppress I and I independently of 5-lipoxygenase inhibition. European Journal of Pharmacology. 173482. PMID 32795513 DOI: 10.1016/j.ejphar.2020.173482   
2020 Kim JH, Won J, Oh SB. Expression of Ca3.1 T-type Calcium Channels in Acutely Isolated Adult Rat Odontoblasts. Archives of Oral Biology. 118: 104864. PMID 32847753 DOI: 10.1016/j.archoralbio.2020.104864   
2020 Nam YW, Cui M, Orfali R, Viegas A, Nguyen M, Mohammed EHM, Zoghebi KA, Rahighi S, Parang K, Zhang M. Hydrophobic interactions between the HA helix and S4-S5 linker modulate apparent Ca sensitivity of SK2 channels. Acta Physiologica (Oxford, England). e13552. PMID 32865319 DOI: 10.1111/apha.13552   
2020 Tsai YM, Jones F, Mullen P, Porter KE, Steele D, Peers C, Gamper N. Vascular Kv7 channels control intracellular Ca dynamics in smooth muscle. Cell Calcium. 92: 102283. PMID 32950876 DOI: 10.1016/j.ceca.2020.102283   
2020 Pantazis A, Kaneko M, Angelini M, Steccanella F, Westerlund AM, Lindström SH, Nilsson M, Delemotte L, Saitta SC, Olcese R. Tracking the motion of K 1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy. The Journal of Physiology. PMID 32833227 DOI: 10.1113/JP280438   
2020 Sun J, Liu Y, Baudry M, Bi X. SK2 channel regulation of neuronal excitability, synaptic transmission, and brain rhythmic activity in health and diseases. Biochimica Et Biophysica Acta. Molecular Cell Research. 118834. PMID 32860835 DOI: 10.1016/j.bbamcr.2020.118834   
2020 Zhang Q, Dou H, Rorsman P. 'Resistance is futile?' - paradoxical inhibitory effects of K channel closure in glucagon-secreting α-cells. The Journal of Physiology. PMID 32716554 DOI: 10.1113/JP279775   
2020 López-Vera E, Martínez-Hernández L, Aguilar MB, Carrillo E, Gajewiak J. Studies of Conorfamide-Sr3 on Human Voltage-Gated Kv1 Potassium Channel Subtypes. Marine Drugs. 18. PMID 32823677 DOI: 10.3390/md18080425   
2020 McGahan K, Keener J. A mathematical model analyzing temperature threshold dependence in cold sensitive neurons. Plos One. 15: e0237347. PMID 32785272 DOI: 10.1371/journal.pone.0237347   
2020 Wang F, Li A, Meng TG, Wang LY, Wang LJ, Hou Y, Schatten H, Sun QY, Ou XH. Regulation of [Ca] oscillations and mitochondrial activity by various calcium transporters in mouse oocytes. Reproductive Biology and Endocrinology : Rb&E. 18: 87. PMID 32799904 DOI: 10.1186/s12958-020-00643-7   
2020 Zhang M, Zou B, Gunaratna MJ, Weerasekara S, Tong Z, Nguyen TDT, Koldas S, Cao WS, Pascual C, Xie XS, Hua DH. SYNTHESIS OF 1,3,4-OXADIAZOLES AS SELECTIVE T-TYPE CALCIUM CHANNEL INHIBITORS. Heterocycles. 101: 145-164. PMID 32773946 DOI: 10.3987/com-19-s(f)5   
2020 Boente-Juncal A, Raposo-Garcia S, Costas C, Louzao MC, Vale C, Botana LM. Partial blockade of human voltage-dependent sodium channels by the marine toxins azaspiracids. Chemical Research in Toxicology. PMID 32872774 DOI: 10.1021/acs.chemrestox.0c00216   
2020 Woo J, Jang MW, Lee J, Koh W, Mikoshiba K, Lee CJ. The molecular mechanism of synaptic activity-induced astrocytic volume transient. The Journal of Physiology. PMID 32706443 DOI: 10.1113/JP279741   
2020 Thorington GU, Hessinger DA. Activated L-Type Calcium Channels Inhibit Chemosensitized Nematocyst Discharge from Sea Anemone Tentacles. The Biological Bulletin. 238: 180-192. PMID 32597714 DOI: 10.1086/708947   
2020 Clatot J, Neyroud N, Cox R, Souil C, Huang J, Guicheney P, Antzelevitch C. Inter-Regulation of K4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies. International Journal of Molecular Sciences. 21. PMID 32709127 DOI: 10.3390/ijms21145057   
2020 Fan C, Yang X, Wang WW, Wang J, Li W, Guo M, Huang S, Wang Z, Liu K. Role of Kv1.3 Channels in Platelet Functions and Thrombus Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314278. PMID 32787516 DOI: 10.1161/ATVBAHA.120.314278   
2020 van der Horst J, Greenwood IA, Jepps TA. Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels. Frontiers in Physiology. 11: 727. PMID 32695022 DOI: 10.3389/fphys.2020.00727   
2020 Szteyn K, Singh H. BK Channels as Targets for Cardioprotection. Antioxidants (Basel, Switzerland). 9. PMID 32824463 DOI: 10.3390/antiox9080760   
2020 Idoux R, Fuster C, Jacquemond V, Dayal A, Grabner M, Charnet P, Allard B. Divalent cations permeation in a Ca non-conducting skeletal muscle dihydropyridine receptor mouse model. Cell Calcium. 91: 102256. PMID 32866694 DOI: 10.1016/j.ceca.2020.102256   
2020 Alves QL, Moraes RDA, Froes TQ, Castilho MS, Aquino de Araújo RS, Barbosa-Filho JM, Meira CS, Pereira Soares MB, Silva DF. Inhibition of intracellular Ca mobilization and potassium channels activation are involved in the vasorelaxation induced by 7-hydroxycoumarin. European Journal of Pharmacology. 173525. PMID 32889064 DOI: 10.1016/j.ejphar.2020.173525   
2020 Zhang H, Zhang S, Wang W, Wang K, Shen W. A Mathematical Model of the Mouse Atrial Myocyte With Inter-Atrial Electrophysiological Heterogeneity. Frontiers in Physiology. 11: 972. PMID 32848887 DOI: 10.3389/fphys.2020.00972   
2020 Chakouri N, Diaz J, Yang PS, Ben-Johny M. Ca channels reject signaling from a second CaM in eliciting Ca-dependent feedback regulation. The Journal of Biological Chemistry. PMID 32820053 DOI: 10.1074/jbc.RA120.013777   
2020 Scheuer R, Philipp SE, Becker A, Nalbach L, Ampofo E, Montenarh M, Götz C. Protein Kinase CK2 Controls Ca2.1-Dependent Calcium Currents and Insulin Release in Pancreatic β-Cells. International Journal of Molecular Sciences. 21. PMID 32630015 DOI: 10.3390/ijms21134668   
2020 Maldonado O, Jenkins A, Belalcazar HM, Hernandez-Cuervo H, Hyman KM, Ladaga G, Padilla L, de Erausquin GA. Age-dependent neuroprotective effect of an SK3 channel agonist on excitotoxity to dopaminergic neurons in organotypic culture. Plos One. 15: e0223633. PMID 32701951 DOI: 10.1371/journal.pone.0223633   
2020 Rahban R, Nef S. CatSper: The complex main gate of calcium entry in mammalian spermatozoa. Molecular and Cellular Endocrinology. 110951. PMID 32712386 DOI: 10.1016/j.mce.2020.110951   
2020 Fritzius T, Stawarski M, Isogai S, Bettler B. Structural Basis of GABA Receptor Regulation and Signaling. Current Topics in Behavioral Neurosciences. PMID 32812202 DOI: 10.1007/7854_2020_147   
2020 Sherikar AS, Bhatia MS, Dhavale RP. Identification and Investigation of Chalcone Derivatives as Calcium Channel Blockers: Pharmacophore modeling, Docking studies, In-vitro screening, and 3D-QSAR Analysis. Current Computer-Aided Drug Design. PMID 32664842 DOI: 10.2174/1573409916666200714143930   
2020 Zhang Q, Si Y, Yang L, Wang L, Peng S, Chen Y, Chen M, Zhou X, Liu Z. Two Novel Peptide Toxins from the Spider Inhibit Tetrodotoxin-Sensitive Sodium Channels. Toxins. 12. PMID 32824960 DOI: 10.3390/toxins12090529   
2020 Chapotte-Baldacci CA, Lizot G, Jajkiewicz C, Lévêque M, Penna A, Magaud C, Thoreau V, Bois P, Sebille S, Chatelier A. Fine Tuning of Calcium Constitutive Entry by Optogenetically-Controlled Membrane Polarization: Impact on Cell Migration. Cells. 9. PMID 32668787 DOI: 10.3390/cells9071684   
2020 Rose P, Schleimer JH, Schreiber S. Modifications of sodium channel voltage dependence induce arrhythmia-favouring dynamics of cardiac action potentials. Plos One. 15: e0236949. PMID 32750067 DOI: 10.1371/journal.pone.0236949   
2020 Hong L, Zhang M, Sridhar A, Darbar D. Pathogenic mutations perturb calmodulin regulation of Na1.8 channel. Biochemical and Biophysical Research Communications. PMID 32948286 DOI: 10.1016/j.bbrc.2020.08.010   
2020 Zhou A, Liu X, Zhang S, Huo B. Effects of store-operated and receptor-operated calcium channels on synchronization of calcium oscillations in astrocytes. Bio Systems. 104233. PMID 32858094 DOI: 10.1016/j.biosystems.2020.104233   
2020 Mondéjar-Parreño G, Barreira B, Callejo M, Morales-Cano D, Barrese V, Esquivel-Ruiz S, Olivencia MA, Macías M, Moreno L, Greenwood IA, Perez-Vizcaino F, Cogolludo A. Uncovered Contribution of Kv7 Channels to Pulmonary Vascular Tone in Pulmonary Arterial Hypertension. Hypertension (Dallas, Tex. : 1979). 76: 1134-1146. PMID 32829658 DOI: 10.1161/HYPERTENSIONAHA.120.15221   
2020 Cherny VV, Musset B, Morgan D, Thomas S, Smith SME, DeCoursey TE. Engineered high-affinity zinc binding site reveals gating configurations of a human proton channel. The Journal of General Physiology. 152. PMID 32902579 DOI: 10.1085/jgp.202012664   
2020 Gürtler F, Jordan K, Tegtmeier I, Herold J, Stindl J, Warth R, Bandulik S. Cellular Pathophysiology of Mutant Voltage-Dependent Ca2+ Channel CACNA1H in Primary Aldosteronism. Endocrinology. 161. PMID 32785697 DOI: 10.1210/endocr/bqaa135   
2020 Schecterson LC, Pazevic AA, Yang R, Matulef K, Gordon SE. TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3. Molecular Vision. 26: 576-587. PMID 32863706   
2020 Han L, Wu A, Li Q, Xia Z, Wu Y, Hong K, Xia Z, Li J. Homocysteine-induced electrical remodeling via the mediation of IPR1/Nav1.5 signaling pathway. American Journal of Translational Research. 12: 3822-3841. PMID 32774738   
2020 Kim MK, Han AY, Shin YK, Lee KW, Seol GH. Codonopsis lanceolata Contributes to Ca2+ Homeostasis by Mediating SOCE and PLC/IP3 Pathways in Vascular Endothelial and Smooth Muscle Cells. Planta Medica. PMID 32731264 DOI: 10.1055/a-1214-6718