| Year |
Citation |
Score |
| 2021 |
Jennewein MF, MacCamy AJ, Akins NR, Feng J, Homad LJ, Hurlburt NK, Seydoux E, Wan YH, Stuart AB, Edara VV, Floyd K, Vanderheiden A, Mascola JR, Doria-Rose N, Wang L, ... ... Ward AB, et al. Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects. Cell Reports. 109353. PMID 34237283 DOI: 10.1016/j.celrep.2021.109353 |
0.313 |
|
| 2021 |
Zost SJ, Dong J, Gilchuk IM, Gilchuk P, Thornburg NJ, Bangaru S, Kose N, Finn JA, Bombardi R, Soto C, Chen EC, Nargi RS, Sutton RE, Irving RP, Suryadevara N, ... ... Ward AB, et al. Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface. The Journal of Clinical Investigation. PMID 34156974 DOI: 10.1172/JCI146791 |
0.311 |
|
| 2021 |
Kumar S, Lin X, Ngo T, Shapero B, Sou C, Allen JD, Copps J, Zhang L, Ozorowski G, He L, Crispin M, Ward AB, Wilson IA, Zhu J. Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles. Mbio. e0042921. PMID 34156262 DOI: 10.1128/mBio.00429-21 |
0.321 |
|
| 2021 |
Guthmiller JJ, Han J, Li L, Freyn AW, Liu STH, Stovicek O, Stamper CT, Dugan HL, Tepora ME, Utset HA, Bitar DJ, Hamel NJ, Changrob S, Zheng NY, Huang M, ... ... Ward AB, et al. First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Science Translational Medicine. 13. PMID 34078743 DOI: 10.1126/scitranslmed.abg4535 |
0.312 |
|
| 2021 |
van Haaren MM, McCoy LE, Torres JL, Lee W, Cottrell CA, Copps JL, van der Woude P, Yasmeen A, de Taeye SW, de la Peña AT, Moore JP, Burton DR, Klasse PJ, Ward AB, Sanders RW, et al. Antibodies from rabbits immunized with HIV-1 clade B SOSIP trimers can neutralize multiple clade B viruses by destabilizing the envelope glycoprotein. Journal of Virology. JVI0009421. PMID 34076487 DOI: 10.1128/JVI.00094-21 |
0.349 |
|
| 2021 |
Rossignol ED, Dugast AS, Compere H, Cottrell CA, Copps J, Lin S, Cizmeci D, Seaman MS, Ackerman ME, Ward AB, Alter G, Julg B. Mining HIV controllers for broad and functional antibodies to recognize and eliminate HIV-infected cells. Cell Reports. 35: 109167. PMID 34038720 DOI: 10.1016/j.celrep.2021.109167 |
0.328 |
|
| 2021 |
Liu H, Yuan M, Huang D, Bangaru S, Zhao F, Lee CD, Peng L, Barman S, Zhu X, Nemazee D, Burton DR, van Gils MJ, Sanders RW, Kornau HC, Reincke SM, ... ... Ward AB, et al. A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host & Microbe. PMID 33894127 DOI: 10.1016/j.chom.2021.04.005 |
0.333 |
|
| 2021 |
Murin CD, Gilchuk P, Ilinykh PA, Huang K, Kuzmina N, Shen X, Bruhn JF, Bryan AL, Davidson E, Doranz BJ, Williamson LE, Copps J, Alkutkar T, Flyak AI, Bukreyev A, ... ... Ward AB, et al. Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies. Cell Reports. 35: 108984. PMID 33852862 DOI: 10.1016/j.celrep.2021.108984 |
0.33 |
|
| 2021 |
Kumar R, Deshpande S, Sewall LM, Ozorowski G, Cottrell CA, Lee WH, Holden LG, Richey ST, Chandrawacar AS, Dhiman K, Ashish F, Kumar V, Ahmed S, Hingankar N, Kumar N, ... ... Ward AB, et al. Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer. Plos Pathogens. 17: e1008977. PMID 33826683 DOI: 10.1371/journal.ppat.1008977 |
0.355 |
|
| 2021 |
Cho H, Gonzales-Wartz KK, Huang D, Yuan M, Peterson M, Liang J, Beutler N, Torres JL, Cong Y, Postnikova E, Bangaru S, Talana CA, Shi W, Yang ES, Zhang Y, ... ... Ward AB, et al. Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants. Biorxiv : the Preprint Server For Biology. PMID 33821267 DOI: 10.1101/2021.04.01.437942 |
0.306 |
|
| 2021 |
Jennewein MF, MacCamy AJ, Akins NR, Feng J, Homad LJ, Hurlburt NK, Seydoux E, Wan YH, Stuart AB, Edara VV, Floyd K, Vanderheiden A, Mascola JR, Doria-Rose N, Wang L, ... ... Ward AB, et al. Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects. Biorxiv : the Preprint Server For Biology. PMID 33791692 DOI: 10.1101/2021.03.23.436684 |
0.301 |
|
| 2021 |
Turner HL, Andrabi R, Cottrell CA, Richey ST, Song G, Callaghan S, Anzanello F, Moyer TJ, Abraham W, Melo M, Silva M, Scaringi N, Rakasz EG, Sattentau Q, Irvine DJ, ... ... Ward AB, et al. Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization. Biorxiv : the Preprint Server For Biology. PMID 33619491 DOI: 10.1101/2021.02.16.431310 |
0.374 |
|
| 2021 |
Liu H, Yuan M, Huang D, Bangaru S, Lee CD, Peng L, Zhu X, Nemazee D, van Gils MJ, Sanders RW, Kornau HC, Reincke SM, Pruss H, Kreye J, Wu NC, ... Ward AB, et al. A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Biorxiv : the Preprint Server For Biology. PMID 33594361 DOI: 10.1101/2021.02.11.430866 |
0.333 |
|
| 2021 |
Freyn AW, Han J, Guthmiller JJ, Bailey MJ, Neu K, Turner HL, Rosado VC, Chromikova V, Huang M, Strohmeier S, Liu STH, Simon V, Krammer F, Ward AB, Palese P, et al. Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33593910 DOI: 10.1073/pnas.2018102118 |
0.323 |
|
| 2021 |
Charles TP, Burton SL, Arunachalam PS, Cottrell CA, Sewall LM, Bollimpelli VS, Gangadhara S, Dey AK, Ward AB, Shaw GM, Hunter E, Amara RR, Pulendran B, van Gils MJ, Derdeyn CA. The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection. Plos Pathogens. 17: e1009257. PMID 33556148 DOI: 10.1371/journal.ppat.1009257 |
0.365 |
|
| 2021 |
Dingens AS, Pratap P, Malone KD, Hilton SK, Ketas T, Cottrell CA, Overbaugh JM, Moore JP, Klasse PJ, Ward AB, Bloom JD. High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post HIV Env trimer vaccination. Elife. 10. PMID 33438580 DOI: 10.7554/eLife.64281 |
0.331 |
|
| 2020 |
Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity. Immunity. PMID 33242394 DOI: 10.1016/j.immuni.2020.10.023 |
0.317 |
|
| 2020 |
Guthmiller JJ, Lan LY, Fernández-Quintero ML, Han J, Utset HA, Bitar DJ, Hamel NJ, Stovicek O, Li L, Tepora M, Henry C, Neu KE, Dugan HL, Borowska MT, Chen YQ, ... ... Ward AB, et al. Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses. Immunity. PMID 33096040 DOI: 10.1016/j.immuni.2020.10.005 |
0.311 |
|
| 2020 |
Schorcht A, van den Kerkhof TLGM, Cottrell CA, Allen JD, Torres JL, Behrens AJ, Schermer EE, Burger JA, de Taeye SW, de la Peña AT, Bontjer I, Gumbs S, Ozorowski G, LaBranche CC, de Val N, ... ... Ward AB, et al. Neutralizing antibody responses induced by HIV-1 envelope glycoprotein SOSIP trimers derived from elite neutralizers. Journal of Virology. PMID 32999024 DOI: 10.1128/JVI.01214-20 |
0.392 |
|
| 2020 |
Zhao F, Joyce C, Burns A, Nogal B, Cottrell CA, Ramos A, Biddle T, Pauthner M, Nedellec R, Qureshi H, Mason R, Landais E, Briney B, Ward AB, Burton DR, et al. Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques. Cell Reports. 32: 108122. PMID 32905766 DOI: 10.1016/J.Celrep.2020.108122 |
0.368 |
|
| 2020 |
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, ... ... Ward AB, et al. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathogens. 16: e1008753. PMID 32866207 DOI: 10.1371/Journal.Ppat.1008753 |
0.368 |
|
| 2020 |
Liu H, Wu NC, Yuan M, Bangaru S, Torres JL, Caniels TG, van Schooten J, Zhu X, Lee CD, Brouwer PJM, van Gils MJ, Sanders RW, Ward AB, Wilson IA. Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity. Biorxiv : the Preprint Server For Biology. PMID 32793906 DOI: 10.1101/2020.08.02.233536 |
0.32 |
|
| 2020 |
Ueda G, Antanasijevic A, Fallas JA, Sheffler W, Copps J, Ellis D, Hutchinson GB, Moyer A, Yasmeen A, Tsybovsky Y, Park YJ, Bick MJ, Sankaran B, Gillespie RA, Brouwer PJ, ... ... Ward AB, et al. Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. Elife. 9. PMID 32748788 DOI: 10.7554/Elife.57659 |
0.309 |
|
| 2020 |
Nogal B, McCoy LE, van Gils MJ, Cottrell CA, Voss JE, Andrabi R, Pauthner M, Liang CH, Messmer T, Nedellec R, Shin M, Turner HL, Ozorowski G, Sanders RW, Burton DR, ... Ward AB, et al. HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite. Science Advances. 6: eaba0512. PMID 32548265 DOI: 10.1126/Sciadv.Aba0512 |
0.345 |
|
| 2020 |
Brouwer PJM, Caniels TG, van der Straten K, Snitselaar JL, Aldon Y, Bangaru S, Torres JL, Okba NMA, Claireaux M, Kerster G, Bentlage AEH, van Haaren MM, Guerra D, Burger JA, Schermer EE, ... ... Ward AB, et al. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability. Science (New York, N.Y.). PMID 32540902 DOI: 10.1126/Science.Abc5902 |
0.327 |
|
| 2020 |
Stanfield RL, Berndsen ZT, Huang R, Sok D, Warner G, Torres JL, Burton DR, Ward AB, Wilson IA, Smider VV. Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Science Advances. 6: eaba0468. PMID 32518821 DOI: 10.1126/Sciadv.Aba0468 |
0.352 |
|
| 2020 |
Seabright GE, Cottrell CA, van Gils MJ, D'addabbo A, Harvey DJ, Behrens AJ, Allen JD, Watanabe Y, Scaringi N, Polveroni TM, Maker A, Vasiljevic S, de Val N, Sanders RW, Ward AB, et al. Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions. Structure (London, England : 1993). PMID 32433992 DOI: 10.1016/j.str.2020.04.022 |
0.307 |
|
| 2020 |
Rantalainen K, Berndsen ZT, Antanasijevic A, Schiffner T, Zhang X, Lee WH, Torres JL, Zhang L, Irimia A, Copps J, Zhou KH, Kwon YD, Law WH, Schramm CA, Verardi R, ... ... Ward AB, et al. HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. Cell Reports. 31: 107583. PMID 32348769 DOI: 10.1016/J.Celrep.2020.107583 |
0.332 |
|
| 2020 |
Nogal B, Bianchi M, Cottrell CA, Kirchdoerfer RN, Sewall LM, Turner HL, Zhao F, Sok D, Burton DR, Hangartner L, Ward AB. Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines. Cell Reports. 30: 3755-3765.e7. PMID 32187547 DOI: 10.1016/j.celrep.2020.02.061 |
0.358 |
|
| 2020 |
Oyen D, Torres JL, Aoto PC, Flores-Garcia Y, Binter S, Pholcharee T, Carroll S, Reponen S, Wash R, Liang Q, Lemiale F, Locke E, Bradley A, King CR, Emerling D, ... ... Ward AB, et al. Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein. Plos Pathogens. 16: e1008373. PMID 32150583 DOI: 10.1371/Journal.Ppat.1008373 |
0.316 |
|
| 2020 |
Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, ... ... Ward AB, et al. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity. PMID 32023489 DOI: 10.1016/J.Immuni.2020.01.001 |
0.337 |
|
| 2020 |
Yang YR, McCoy LE, Gils MJv, Andrabi R, Turner HL, Yuan M, Cottrell CA, Ozorowski G, Voss J, Pauthner M, Polveroni TM, Messmer T, Wilson IA, Sanders RW, Burton DR, ... Ward AB, et al. Autologous neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened in rabbits. Journal of Virology. DOI: 10.2210/Pdb6U59/Pdb |
0.303 |
|
| 2019 |
Zhang L, Irimia A, He L, Landais E, Rantalainen K, Leaman DP, Vollbrecht T, Stano A, Sands DI, Kim AS, Poignard P, Burton DR, Murrell B, Ward AB, et al. An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nature Communications. 10: 5389. PMID 31772165 DOI: 10.1038/S41467-019-12973-1 |
0.34 |
|
| 2019 |
Zhu X, Turner HL, Lang S, McBride R, Bangaru S, Gilchuk IM, Yu W, Paulson JC, Crowe JE, Ward AB, Wilson IA. Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host & Microbe. PMID 31757767 DOI: 10.1016/J.Chom.2019.10.002 |
0.304 |
|
| 2019 |
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell CA, Turner HL, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman DP, Vázquez Bernat N, ... ... Ward AB, et al. Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability. Immunity. PMID 31732167 DOI: 10.1016/J.Immuni.2019.10.008 |
0.348 |
|
| 2019 |
Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, ... ... Ward AB, et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science (New York, N.Y.). PMID 31672916 DOI: 10.1126/Science.Aax4380 |
0.372 |
|
| 2019 |
Ringe RP, Colin P, Torres JL, Yasmeen A, Lee WH, Cupo A, Ward AB, Klasse PJ, Moore JP. SOS and IP modifications predominantly affect the yield but not other properties of SOSIP.664 HIV-1 Env glycoprotein trimers. Journal of Virology. PMID 31619555 DOI: 10.1128/JVI.01521-19 |
0.359 |
|
| 2019 |
Torrents de la Peña A, Rantalainen K, Cottrell CA, Allen JD, van Gils MJ, Torres JL, Crispin M, Sanders RW, Ward AB. Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics. Plos Pathogens. 15: e1007920. PMID 31306470 DOI: 10.1371/journal.ppat.1007920 |
0.345 |
|
| 2019 |
von Bredow B, Andrabi R, Grunst M, Grandea AG, Le K, Song G, Berndsen ZT, Porter K, Pallesen J, Ward AB, Burton DR, Evans DT. Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIV Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization. Mbio. 10. PMID 31266872 DOI: 10.1128/mBio.01255-19 |
0.363 |
|
| 2019 |
Yuan M, Cottrell CA, Ozorowski G, van Gils MJ, Kumar S, Wu NC, Sarkar A, Torres JL, de Val N, Copps J, Moore JP, Sanders RW, Ward AB, Wilson IA. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host & Microbe. 25: 873-883.e5. PMID 31194940 DOI: 10.1016/J.Chom.2019.04.011 |
0.344 |
|
| 2019 |
Sliepen K, Han BW, Bontjer I, Mooij P, Garces F, Behrens AJ, Rantalainen K, Kumar S, Sarkar A, Brouwer PJM, Hua Y, Tolazzi M, Schermer E, Torres JL, Ozorowski G, ... ... Ward AB, et al. Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nature Communications. 10: 2355. PMID 31142746 DOI: 10.1038/S41467-019-10262-5 |
0.334 |
|
| 2019 |
Andrabi R, Pallesen J, Allen JD, Song G, Zhang J, de Val N, Gegg G, Porter K, Su CY, Pauthner M, Newman A, Bouton-Verville H, Garces F, Wilson IA, Crispin M, ... ... Ward AB, et al. The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template. Cell Reports. 27: 2426-2441.e6. PMID 31116986 DOI: 10.1016/J.Celrep.2019.04.082 |
0.315 |
|
| 2019 |
Lei L, Yang YR, Tran K, Wang Y, Chiang CI, Ozorowski G, Xiao Y, Ward AB, Wyatt RT, Li Y. The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization. Cell Reports. 27: 586-598.e6. PMID 30970260 DOI: 10.1016/J.Celrep.2019.03.039 |
0.313 |
|
| 2019 |
Murin CD, Wilson IA, Ward AB. Antibody responses to viral infections: a structural perspective across three different enveloped viruses. Nature Microbiology. PMID 30886356 DOI: 10.1038/S41564-019-0392-Y |
0.331 |
|
| 2019 |
Ward AB. Playing Chess with HIV. Immunity. 50: 283-285. PMID 30784575 DOI: 10.1016/j.immuni.2019.01.011 |
0.314 |
|
| 2019 |
Whitaker N, Hickey JM, Kaur K, Xiong J, Sawant N, Cupo A, Lee WH, Ozorowski G, Medina-Ramírez M, Ward AB, Sanders RW, Moore JP, Joshi SB, Volkin DB, Dey AK. Developability assessment of physicochemical properties and stability profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 envelope glycoprotein trimers as candidate vaccine antigens. Journal of Pharmaceutical Sciences. PMID 30776383 DOI: 10.1016/J.Xphs.2019.01.033 |
0.304 |
|
| 2019 |
Kumar S, Sarkar A, Pugach P, Sanders RW, Moore JP, Ward AB, Wilson IA. Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide. Nature Communications. 10: 763. PMID 30770829 DOI: 10.1038/s41467-019-08738-5 |
0.315 |
|
| 2019 |
de Taeye SW, Go EP, Sliepen K, Torrents de la Peña A, Badal K, Medina-Ramirez M, Lee WH, Desaire H, Wilson IA, Moore JP, Ward AB, Sanders RW. Stabilization of the V2 loop improves the presentation of V2 loop-associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers. The Journal of Biological Chemistry. PMID 30728245 DOI: 10.1074/Jbc.Ra118.005396 |
0.304 |
|
| 2019 |
Turner HL, Pallesen J, Lang S, Bangaru S, Urata S, Li S, Cottrell CA, Bowman CA, Crowe JE, Wilson IA, Ward AB. Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. Plos Biology. 17: e3000139. PMID 30716060 DOI: 10.1371/Journal.Pbio.3000139 |
0.302 |
|
| 2019 |
Dubrovskaya V, Tran K, Ozorowski G, Guenaga J, Wilson R, Bale S, Cottrell C, Seabright G, O'Dell S, Torres JL, Yang L, Feng Y, Leaman D, Bernat NV, Turner H, ... ... Ward AB, et al. Vaccine-elicited cross-neutralizing HIV antibodies directed to multiple sites of Env vulnerability following heterologous NFL trimer-liposome prime:boosting Immunity. DOI: 10.2210/Pdb6P65/Pdb |
0.325 |
|
| 2018 |
Pauthner MG, Nkolola JP, Havenar-Daughton C, Murrell B, Reiss SM, Bastidas R, Prévost J, Nedellec R, von Bredow B, Abbink P, Cottrell CA, Kulp DW, Tokatlian T, Nogal B, Bianchi M, ... ... Ward AB, et al. Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers. Immunity. PMID 30552025 DOI: 10.1016/J.Immuni.2018.11.011 |
0.313 |
|
| 2018 |
Ringe RP, Pugach P, Cottrell CA, LaBranche CC, Seabright GE, Ketas TJ, Ozorowski G, Kumar S, Schorcht A, van Gils MJ, Crispin M, Montefiori DC, Wilson IA, Ward AB, Sanders RW, et al. Closing and opening holes in the glycan shield of HIV-1 envelope glycoprotein SOSIP trimers can redirect the neutralizing antibody response to the newly unmasked epitopes. Journal of Virology. PMID 30487280 DOI: 10.1128/Jvi.01656-18 |
0.369 |
|
| 2018 |
He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, et al. HIV-1 vaccine design through minimizing envelope metastability. Science Advances. 4: eaau6769. PMID 30474059 DOI: 10.1126/Sciadv.Aau6769 |
0.307 |
|
| 2018 |
Laursen NS, Friesen RHE, Zhu X, Jongeneelen M, Blokland S, Vermond J, van Eijgen A, Tang C, van Diepen H, Obmolova G, van der Neut Kolfschoten M, Zuijdgeest D, Straetemans R, Hoffman RMB, Nieusma T, ... ... Ward AB, et al. Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science (New York, N.Y.). 362: 598-602. PMID 30385580 DOI: 10.1126/Science.Aaq0620 |
0.3 |
|
| 2018 |
Aldon Y, McKay PF, Allen J, Ozorowski G, Felfödiné Lévai R, Tolazzi M, Rogers P, He L, de Val N, Fábián K, Scarlatti G, Zhu J, Ward AB, Crispin M, Shattock RJ. Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers. Cell Reports. 24: 3324-3338.e5. PMID 30232012 DOI: 10.1016/J.Celrep.2018.08.051 |
0.362 |
|
| 2018 |
Cao L, Pauthner M, Andrabi R, Rantalainen K, Berndsen Z, Diedrich JK, Menis S, Sok D, Bastidas R, Park SR, Delahunty CM, He L, Guenaga J, Wyatt RT, Schief WR, ... Ward AB, et al. Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer. Nature Communications. 9: 3693. PMID 30209313 DOI: 10.1038/s41467-018-06121-4 |
0.338 |
|
| 2018 |
Murin CD, Bruhn JF, Bornholdt ZA, Copps J, Stanfield R, Ward AB. Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop. Cell Reports. 24: 2723-2732.e4. PMID 30184505 DOI: 10.1016/j.celrep.2018.08.009 |
0.336 |
|
| 2018 |
Bianchi M, Turner HL, Nogal B, Cottrell CA, Oyen D, Pauthner M, Bastidas R, Nedellec R, McCoy LE, Wilson IA, Burton DR, Ward AB, Hangartner L. Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity. PMID 30097292 DOI: 10.1016/J.Immuni.2018.07.009 |
0.335 |
|
| 2018 |
Bangaru S, Zhang H, Gilchuk IM, Voss TG, Irving RP, Gilchuk P, Matta P, Zhu X, Lang S, Nieusma T, Richt JA, Albrecht RA, Vanderven HA, Bombardi R, Kent SJ, ... Ward AB, et al. A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nature Communications. 9: 2669. PMID 29991715 DOI: 10.1038/S41467-018-04704-9 |
0.31 |
|
| 2018 |
Rantalainen K, Berndsen ZT, Murrell S, Cao L, Omorodion O, Torres JL, Wu M, Umotoy J, Copps J, Poignard P, Landais E, Paulson JC, Wilson IA, Ward AB. Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Reports. 23: 3249-3261. PMID 29898396 DOI: 10.1016/J.Celrep.2018.05.046 |
0.378 |
|
| 2018 |
Bale S, Martiné A, Wilson R, Behrens AJ, Le Fourn V, de Val N, Sharma SK, Tran K, Torres JL, Girod PA, Ward AB, Crispin M, Wyatt RT. Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies. Frontiers in Immunology. 9: 1116. PMID 29881382 DOI: 10.3389/Fimmu.2018.01116 |
0.351 |
|
| 2018 |
Sarkar A, Bale S, Behrens AJ, Kumar S, Sharma SK, de Val N, Pallesen J, Irimia A, Diwanji DC, Stanfield RL, Ward AB, Crispin M, Wyatt RT, Wilson IA. Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer. Nature Communications. 9: 1956. PMID 29769533 DOI: 10.1038/S41467-018-04272-Y |
0.31 |
|
| 2018 |
Schiffner T, Pallesen J, Russell RA, Dodd J, de Val N, LaBranche CC, Montefiori D, Tomaras GD, Shen X, Harris SL, Moghaddam AE, Kalyuzhniy O, Sanders RW, McCoy LE, Moore JP, ... Ward AB, et al. Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins. Plos Pathogens. 14: e1006986. PMID 29746590 DOI: 10.1371/journal.ppat.1006986 |
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| 2018 |
Flyak AI, Kuzmina N, Murin CD, Bryan C, Davidson E, Gilchuk P, Gulka CP, Ilinykh PA, Shen X, Huang K, Ramanathan P, Turner H, Fusco ML, Lampley R, Kose N, ... ... Ward AB, et al. Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region. Nature Microbiology. PMID 29736037 DOI: 10.1038/S41564-018-0157-Z |
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| 2018 |
Ozorowski G, Cupo A, Golabek M, LoPiccolo M, Ketas TA, Cavallary M, Cottrell CA, Klasse PJ, Ward AB, Moore JP. Effects of adjuvants on HIV-1 envelope glycoprotein SOSIP trimers . Journal of Virology. PMID 29669838 DOI: 10.1128/Jvi.00381-18 |
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| 2018 |
Crispin M, Ward AB, Wilson IA. Structure and Immune Recognition of the HIV Glycan Shield. Annual Review of Biophysics. PMID 29595997 DOI: 10.1146/Annurev-Biophys-060414-034156 |
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| 2018 |
Steinhardt JJ, Guenaga J, Turner HL, McKee K, Louder MK, O'Dell S, Chiang CI, Lei L, Galkin A, Andrianov AK, A Doria-Rose N, Bailer RT, Ward AB, Mascola JR, Li Y. Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity. Nature Communications. 9: 877. PMID 29491415 DOI: 10.1038/s41467-018-03335-4 |
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| 2018 |
Klasse PJ, Ketas TJ, Cottrell CA, Ozorowski G, Debnath G, Camara D, Francomano E, Pugach P, Ringe RP, LaBranche CC, van Gils MJ, Bricault CA, Barouch DH, Crotty S, Silvestri G, ... ... Ward AB, et al. Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques. Plos Pathogens. 14: e1006913. PMID 29474444 DOI: 10.1371/Journal.Ppat.1006913 |
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| 2018 |
Shrivastava T, Samal S, Tyagi AK, Goswami S, Kumar N, Ozorowski G, Ward AB, Chakrabarti BK. Envelope proteins of two HIV-1 clades induced different epitope-specific antibody response. Vaccine. PMID 29429810 DOI: 10.1016/J.Vaccine.2018.01.081 |
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| 2017 |
de Taeye SW, Torrents de la Peña A, Vecchione A, Scutigliani E, Sliepen K, Burger JA, van der Woude P, Schorcht A, Schermer EE, van Gils MJ, LaBranche CC, Montefiori DC, Wilson IA, Moore JP, Ward AB, et al. Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers. The Journal of Biological Chemistry. PMID 29222332 DOI: 10.1074/Jbc.Ra117.000709 |
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| 2017 |
Landais E, Murrell B, Briney B, Murrell S, Rantalainen K, Berndsen ZT, Ramos A, Wickramasinghe L, Smith ML, Eren K, de Val N, Wu M, Cappelletti A, Umotoy J, Lie Y, ... ... Ward AB, et al. HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity. 47: 990-1003.e9. PMID 29166592 DOI: 10.1016/J.Immuni.2017.11.002 |
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| 2017 |
Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E, Kalyuzhniy O, Willis JR, Kubitz M, Adachi Y, Reiss SM, ... ... Ward AB, et al. Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding. Nature Communications. 8: 1655. PMID 29162799 DOI: 10.1038/S41467-017-01549-6 |
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| 2017 |
Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su CY, Sok D, Khan SN, Garces F, Pritchard LK, Wyatt RT, Ward AB, Crispin M, Wilson IA, et al. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Reports. 21: 222-235. PMID 28978475 DOI: 10.1016/J.Celrep.2017.09.024 |
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| 2017 |
Dubrovskaya V, Guenaga J, de Val N, Wilson R, Feng Y, Movsesyan A, Karlsson Hedestam GB, Ward AB, Wyatt RT. Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response. Plos Pathogens. 13: e1006614. PMID 28902916 DOI: 10.1371/Journal.Ppat.1006614 |
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| 2017 |
He L, Lin X, de Val N, Saye-Francisco KL, Mann CJ, Augst R, Morris CD, Azadnia P, Zhou B, Sok D, Ozorowski G, Ward AB, Burton DR, Zhu J. Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer. Frontiers in Immunology. 8: 1025. PMID 28883821 DOI: 10.3389/Fimmu.2017.01025 |
0.355 |
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| 2017 |
Sullivan JT, Sulli C, Nilo A, Yasmeen A, Ozorowski G, Sanders RW, Ward AB, Klasse PJ, Moore JP, Doranz BJ. High-throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers. Journal of Virology. PMID 28878072 DOI: 10.1128/Jvi.00862-17 |
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| 2017 |
Medina-Ramírez M, Garces F, Escolano A, Skog P, de Taeye SW, Del Moral-Sanchez I, McGuire AT, Yasmeen A, Behrens AJ, Ozorowski G, van den Kerkhof TLGM, Freund NT, Dosenovic P, Hua Y, Gitlin AD, ... ... Ward AB, et al. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. The Journal of Experimental Medicine. PMID 28847869 DOI: 10.1084/Jem.20161160 |
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| 2017 |
Wang Y, O'Dell S, Turner HL, Chiang CI, Lei L, Guenaga J, Wilson R, Martinez-Murillo P, Doria-Rose N, Ward AB, Mascola JR, Wyatt RT, Karlsson Hedestam GB, Li Y. HIV-1 Cross-reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Non-human Primate. Journal of Virology. PMID 28835491 DOI: 10.1128/Jvi.00910-17 |
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| 2017 |
Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, ... ... Ward AB, et al. Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization. Cell Reports. 20: 1805-1817. PMID 28834745 DOI: 10.1016/J.Celrep.2017.07.077 |
0.35 |
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| 2017 |
Koch K, Kalusche S, Torres JL, Stanfield RL, Danquah W, Khazanehdari K, von Briesen H, Geertsma ER, Wilson IA, Wernery U, Koch-Nolte F, Ward AB, Dietrich U. Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers. Scientific Reports. 7: 8390. PMID 28827559 DOI: 10.1038/S41598-017-08273-7 |
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| 2017 |
Kumar R, Ozorowski G, Kumar V, Holden LG, Shrivastava T, Patil S, Deshpande S, Ward AB, Bhattacharya J. Characterization of a stable HIV-1 B/C recombinant, soluble and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes. The Journal of Biological Chemistry. PMID 28743743 DOI: 10.1074/Jbc.M117.803056 |
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| 2017 |
Sok D, Le KM, Vadnais M, Saye-Francisco K, Jardine JG, Torres J, Berndsen ZT, Kong L, Stanfield R, Ruiz J, Ramos A, Liang CH, Chen PL, Criscitiello MF, Mwangi W, ... ... Ward AB, et al. Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows. Nature. PMID 28726771 DOI: 10.1038/Nature23301 |
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| 2017 |
Ozorowski G, Pallesen J, de Val N, Lyumkis D, Cottrell CA, Torres JL, Copps J, Stanfield RL, Cupo A, Pugach P, Moore JP, Wilson IA, Ward AB. Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike. Nature. PMID 28700571 DOI: 10.1038/Nature23010 |
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| 2017 |
Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Ward AB, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007 |
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| 2017 |
Ringe RP, Ozorowski G, Rantalainen K, Struwe WB, Matthews K, Torres JL, Yasmeen A, Cottrell CA, Ketas TJ, LaBranche CC, Montefiori DC, Cupo A, Crispin M, Wilson IA, Ward AB, et al. Reducing V3 antigenicity and immunogenicity on soluble, native-like HIV-1 Env SOSIP trimers. Journal of Virology. PMID 28539451 DOI: 10.1128/Jvi.00677-17 |
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| 2017 |
Zhao X, Howell KA, He S, Brannan JM, Wec AZ, Davidson E, Turner HL, Chiang CI, Lei L, Fels JM, Vu H, Shulenin S, Turonis AN, Kuehne AI, Liu G, ... ... Ward AB, et al. Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability. Cell. 169: 891-904.e15. PMID 28525756 DOI: 10.1016/J.Cell.2017.04.038 |
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| 2017 |
Wec AZ, Herbert AS, Murin CD, Nyakatura EK, Abelson DM, Fels JM, He S, James RM, de La Vega MA, Zhu W, Bakken RR, Goodwin E, Turner HL, Jangra RK, Zeitlin L, ... ... Ward AB, et al. Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses. Cell. 169: 878-890.e15. PMID 28525755 DOI: 10.1016/J.Cell.2017.04.037 |
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| 2017 |
Guenaga J, Garces F, de Val N, Stanfield RL, Dubrovskaya V, Higgins B, Carrette B, Ward AB, Wilson IA, Wyatt RT. Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein. Immunity. 46: 792-803.e3. PMID 28514686 DOI: 10.1016/J.Immuni.2017.04.014 |
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| 2017 |
Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, ... ... Ward AB, et al. Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity. 46: 777-791.e10. PMID 28514685 DOI: 10.1016/J.Immuni.2017.04.011 |
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| 2017 |
Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, ... ... Ward AB, et al. A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure. Immunity. 46: 690-702. PMID 28423342 DOI: 10.1016/J.Immuni.2017.03.017 |
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| 2017 |
Howell KA, Brannan JM, Bryan C, McNeal A, Davidson E, Turner HL, Vu H, Shulenin S, He S, Kuehne A, Herbert AS, Qiu X, Doranz BJ, Holtsberg FW, Ward AB, et al. Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus. Cell Reports. 19: 413-424. PMID 28402862 DOI: 10.1016/j.celrep.2017.03.049 |
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| 2017 |
Ringe RP, Ozorowski G, Yasmeen A, Cupo A, Cruz Portillo VM, Pugach P, Golabek M, Rantalainen K, Holden LG, Cottrell CA, Wilson IA, Sanders RW, Ward AB, Klasse PJ, Moore JP. Improving the expression and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers by targeted sequence changes. Journal of Virology. PMID 28381572 DOI: 10.1128/Jvi.00264-17 |
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| 2017 |
Ahmed S, Shrivastava T, Kumar N, Ozorowski G, Ward AB, Chakrabarti BK. Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein. The Journal of Biological Chemistry. PMID 28283570 DOI: 10.1074/Jbc.M117.776419 |
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| 2017 |
Morris CD, Azadnia P, de Val N, Vora N, Honda A, Giang E, Saye-Francisco K, Cheng Y, Lin X, Mann CJ, Tang J, Sok D, Burton DR, Law M, Ward AB, et al. Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers. Mbio. 8. PMID 28246356 DOI: 10.1128/mBio.00036-17 |
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| 2017 |
Ward AB, Wilson IA. The HIV-1 envelope glycoprotein structure: nailing down a moving target. Immunological Reviews. 275: 21-32. PMID 28133813 DOI: 10.1111/Imr.12507 |
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| 2017 |
Wibmer CK, Gorman J, Ozorowski G, Bhiman JN, Sheward DJ, Elliott DH, Rouelle J, Smira A, Joyce MG, Ndabambi N, Druz A, Asokan M, Burton DR, Connors M, Abdool Karim SS, ... ... Ward AB, et al. Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. Plos Pathogens. 13: e1006074. PMID 28076415 DOI: 10.1371/Journal.Ppat.1006074 |
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| 2016 |
van Gils MJ, van den Kerkhof TL, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW, Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang CH, ... ... Ward AB, et al. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability. Nature Microbiology. 2: 16199. PMID 27841852 DOI: 10.1038/Nmicrobiol.2016.199 |
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| 2016 |
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, ... ... Ward AB, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016 |
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| 2016 |
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, ... ... Ward AB, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/J.Cell.2016.08.005 |
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| 2016 |
Pallesen J, Murin CD, de Val N, Cottrell CA, Hastie KM, Turner HL, Fusco ML, Flyak AI, Zeitlin L, Crowe JE, Andersen KG, Saphire EO, Ward AB. Structures of Ebola virus GP and sGP in complex with therapeutic antibodies. Nature Microbiology. 1: 16128. PMID 27562261 DOI: 10.1038/Nmicrobiol.2016.128 |
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| 2016 |
McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M, Menis S, Cottrell CA, Torres JL, Hsueh J, Schief WR, ... ... Ward AB, et al. Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies. Cell Reports. PMID 27545891 DOI: 10.1016/J.Celrep.2016.07.074 |
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| 2016 |
Feng Y, Tran K, Bale S, Kumar S, Guenaga J, Wilson R, de Val N, Arendt H, DeStefano J, Ward AB, Wyatt RT. Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies. Plos Pathogens. 12: e1005767. PMID 27487086 DOI: 10.1371/Journal.Ppat.1005767 |
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| 2016 |
Sok D, Pauthner M, Briney B, Lee JH, Saye-Francisco KL, Hsueh J, Ramos A, Le KM, Jones M, Jardine JG, Bastidas R, Sarkar A, Liang CH, Shivatare SS, Wu CY, ... ... Ward AB, et al. A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans. Immunity. 45: 31-45. PMID 27438765 DOI: 10.1016/J.Immuni.2016.06.026 |
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| 2016 |
Howell KA, Qiu X, Brannan JM, Bryan C, Davidson E, Holtsberg FW, Wec AZ, Shulenin S, Biggins JE, Douglas R, Enterlein SG, Turner HL, Pallesen J, Murin CD, He S, ... ... Ward AB, et al. Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site. Cell Reports. PMID 27160900 DOI: 10.1016/J.Celrep.2016.04.026 |
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| 2016 |
Kong L, Ju B, Chen Y, He L, Ren L, Liu J, Hong K, Su B, Wang Z, Ozorowski G, Ji X, Hua Y, Chen Y, Deller MC, Hao Y, ... ... Ward AB, et al. Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor. Immunity. PMID 27067056 DOI: 10.1016/J.Immuni.2016.03.006 |
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| 2016 |
Behrens AJ, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N, Seabright GE, Kramer HB, Spencer DI, Royle L, Lee JH, ... ... Ward AB, et al. Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein. Cell Reports. PMID 26972002 DOI: 10.1016/J.Celrep.2016.02.058 |
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| 2016 |
Lee JH, Ozorowski G, Ward AB. Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 351: 1043-8. PMID 26941313 DOI: 10.1126/Science.Aad2450 |
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| 2016 |
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, ... ... Ward AB, et al. Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak. Science (New York, N.Y.). PMID 26912366 DOI: 10.1126/Science.Aad5788 |
0.336 |
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| 2016 |
Flyak AI, Shen X, Murin CD, Turner HL, David JA, Fusco ML, Lampley R, Kose N, Ilinykh PA, Kuzmina N, Branchizio A, King H, Brown L, Bryan C, Davidson E, ... ... Ward AB, et al. Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection. Cell. PMID 26806128 DOI: 10.1016/J.Cell.2015.12.022 |
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| 2015 |
Guenaga J, Dubrovskaya V, de Val N, Sharma SK, Carrette B, Ward AB, Wyatt RT. Structure-guided redesign increases the propensity of HIV Env to generate highly stable soluble trimers. Journal of Virology. PMID 26719252 DOI: 10.1128/JVI.02652-15 |
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| 2015 |
de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, ... ... Ward AB, et al. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes. Cell. 163: 1702-15. PMID 26687358 DOI: 10.1016/J.Cell.2015.11.056 |
0.31 |
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| 2015 |
Garces F, Lee JH, de Val N, Torrents de la Pena A, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP, Sanders RW, Ward AB, Wilson IA. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity. 43: 1053-63. PMID 26682982 DOI: 10.1016/J.Immuni.2015.11.007 |
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| 2015 |
Sliepen K, van Montfort T, Ozorowski G, Pritchard LK, Crispin M, Ward AB, Sanders RW. Engineering and Characterization of a Fluorescent Native-Like HIV-1 Envelope Glycoprotein Trimer. Biomolecules. 5: 2919-34. PMID 26512709 DOI: 10.3390/biom5042919 |
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| 2015 |
Schiffner T, de Val N, Russell RA, de Taeye SW, Torrents de la Pena A, Ozorowski G, Kim HJ, Nieusma T, Brod F, Cupo A, Sanders RW, Moore JP, Ward AB, Sattentau QJ. Chemical Cross-linking Stabilizes Native-Like HIV-1 Envelope Glycoprotein Trimer Antigens. Journal of Virology. PMID 26512083 DOI: 10.1128/Jvi.01942-15 |
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| 2015 |
Lee JH, Leaman DP, Kim AS, Torrents de la Peña A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, ... ... Ward AB, et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nature Communications. 6: 8167. PMID 26404402 DOI: 10.1038/Ncomms9167 |
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| 2015 |
Julien JP, Lee JH, Ozorowski G, Hua Y, Torrents de la Peña A, de Taeye SW, Nieusma T, Cupo A, Yasmeen A, Golabek M, Pugach P, Klasse PJ, Moore JP, Sanders RW, Ward AB, et al. Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens. Proceedings of the National Academy of Sciences of the United States of America. PMID 26372963 DOI: 10.1073/Pnas.1507793112 |
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| 2015 |
Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW, Cupo A, Crispin M, Lee KK, Desaire H, Ward AB, et al. Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers. Journal of Virology. PMID 26311893 DOI: 10.1128/Jvi.01768-15 |
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| 2015 |
Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I, Stanfield R, Ward AB, Burton DR, Klasse PJ, Sanders RW, et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity. Journal of Virology. PMID 26246566 DOI: 10.1128/Jvi.01653-15 |
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| 2015 |
Fusco ML, Hashiguchi T, Cassan R, Biggins JE, Murin CD, Warfield KL, Li S, Holtsberg FW, Shulenin S, Vu H, Olinger GG, Kim DH, Whaley KJ, Zeitlin L, Ward AB, et al. Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs. Plos Pathogens. 11: e1005016. PMID 26115029 DOI: 10.1371/Journal.Ppat.1005016 |
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| 2015 |
Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, ... ... Ward AB, et al. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science (New York, N.Y.). 349: aac4223. PMID 26089353 DOI: 10.1126/Science.Aac4223 |
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| 2015 |
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR, Wilson IA, Ward AB, Moore JP, Crispin M. Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers. Cell Reports. 11: 1604-13. PMID 26051934 DOI: 10.1016/J.Celrep.2015.05.017 |
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| 2015 |
Sharma SK, de Val N, Bale S, Guenaga J, Tran K, Feng Y, Dubrovskaya V, Ward AB, Wyatt RT. Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design. Cell Reports. 11: 539-50. PMID 25892233 DOI: 10.1016/J.Celrep.2015.03.047 |
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| 2015 |
Leaman DP, Lee JH, Ward AB, Zwick MB. Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes. Journal of Virology. 89: 6725-45. PMID 25878116 DOI: 10.1128/JVI.03738-14 |
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| 2015 |
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. Plos Pathogens. 11: e1004767. PMID 25807248 DOI: 10.1371/Journal.Ppat.1004767 |
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| 2015 |
Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, et al. Mechanism of human antibody-mediated neutralization of Marburg virus. Cell. 160: 893-903. PMID 25723164 DOI: 10.1016/J.Cell.2015.01.031 |
0.308 |
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| 2015 |
Ward AB, Wilson IA. Insights into the trimeric HIV-1 envelope glycoprotein structure. Trends in Biochemical Sciences. 40: 101-7. PMID 25600289 DOI: 10.1016/J.Tibs.2014.12.006 |
0.33 |
|
| 2015 |
Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, Julien JP, Burton DR, Wilson IA, ... ... Ward AB, et al. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. Journal of Virology. 89: 3380-95. PMID 25589637 DOI: 10.1128/Jvi.03473-14 |
0.341 |
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| 2015 |
Guenaga J, de Val N, Tran K, Feng Y, Satchwell K, Ward AB, Wyatt RT. Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties. Plos Pathogens. 11: e1004570. PMID 25569572 DOI: 10.1371/journal.ppat.1004570 |
0.309 |
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| 2014 |
Sok D, van Gils MJ, Pauthner M, Julien JP, Saye-Francisco KL, Hsueh J, Briney B, Lee JH, Le KM, Lee PS, Hua Y, Seaman MS, Moore JP, Ward AB, Wilson IA, et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex. Proceedings of the National Academy of Sciences of the United States of America. 111: 17624-9. PMID 25422458 DOI: 10.1073/Pnas.1415789111 |
0.36 |
|
| 2014 |
Murin CD, Fusco ML, Bornholdt ZA, Qiu X, Olinger GG, Zeitlin L, Kobinger GP, Ward AB, Saphire EO. Structures of protective antibodies reveal sites of vulnerability on Ebola virus. Proceedings of the National Academy of Sciences of the United States of America. 111: 17182-7. PMID 25404321 DOI: 10.1073/Pnas.1414164111 |
0.303 |
|
| 2014 |
Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, Julien JP, Hua Y, Cupo A, Moore JP, Paulson JC, Ward AB, Burton DR, Wilson IA. Structural evolution of glycan recognition by a family of potent HIV antibodies. Cell. 159: 69-79. PMID 25259921 DOI: 10.1016/J.Cell.2014.09.009 |
0.328 |
|
| 2014 |
Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, ... ... Ward AB, et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature. 515: 138-42. PMID 25186731 DOI: 10.1038/Nature13601 |
0.341 |
|
| 2014 |
Yasmeen A, Ringe R, Derking R, Cupo A, Julien JP, Burton DR, Ward AB, Wilson IA, Sanders RW, Moore JP, Klasse PJ. Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits. Retrovirology. 11: 41. PMID 24884783 DOI: 10.1186/1742-4690-11-41 |
0.352 |
|
| 2014 |
Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Peña AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, ... ... Ward AB, et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity. 40: 669-80. PMID 24768348 DOI: 10.1016/J.Immuni.2014.04.008 |
0.326 |
|
| 2014 |
Falkowska E, Le KM, Ramos A, Doores KJ, Lee JH, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang CH, Mcbride R, von Bredow B, Shivatare SS, Wu CY, Chan-Hui PY, ... ... Ward AB, et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers. Immunity. 40: 657-68. PMID 24768347 DOI: 10.1016/J.Immuni.2014.04.009 |
0.373 |
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| 2014 |
Scharf L, Scheid JF, Lee JH, West AP, Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Reports. 7: 785-95. PMID 24767986 DOI: 10.1016/J.Celrep.2014.04.001 |
0.341 |
|
| 2014 |
Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, ... ... Ward AB, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 509: 55-62. PMID 24590074 DOI: 10.1038/Nature13036 |
0.366 |
|
| 2014 |
Tran K, Poulsen C, Guenaga J, de Val N, de Val Alda N, Wilson R, Sundling C, Li Y, Stanfield RL, Wilson IA, Ward AB, Karlsson Hedestam GB, Wyatt RT. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proceedings of the National Academy of Sciences of the United States of America. 111: E738-47. PMID 24550318 DOI: 10.1073/Pnas.1319512111 |
0.337 |
|
| 2013 |
Lyumkis D, Julien JP, de Val N, Cupo A, Potter CS, Klasse PJ, Burton DR, Sanders RW, Moore JP, Carragher B, Wilson IA, Ward AB. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 342: 1484-90. PMID 24179160 DOI: 10.1126/Science.1245627 |
0.321 |
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| 2013 |
Julien JP, Cupo A, Sok D, Stanfield RL, Lyumkis D, Deller MC, Klasse PJ, Burton DR, Sanders RW, Moore JP, Ward AB, Wilson IA. Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 342: 1477-83. PMID 24179159 DOI: 10.1126/Science.1245625 |
0.307 |
|
| 2013 |
Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, de la Peña AT, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, van Gils MJ, King CR, ... ... Ward AB, et al. A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies. Plos Pathogens. 9: e1003618. PMID 24068931 DOI: 10.1371/Journal.Ppat.1003618 |
0.376 |
|
| 2013 |
Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers. Journal of Virology. 87: 9865-72. PMID 23824817 DOI: 10.1128/Jvi.01222-13 |
0.348 |
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| 2013 |
Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, ... ... Ward AB, et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nature Structural & Molecular Biology. 20: 796-803. PMID 23708606 DOI: 10.1038/Nsmb.2594 |
0.344 |
|
| 2013 |
Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, ... ... Ward AB, et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathogens. 9: e1003342. PMID 23658524 DOI: 10.1371/Journal.Ppat.1003342 |
0.33 |
|
| 2013 |
Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, et al. Rational HIV immunogen design to target specific germline B cell receptors. Science (New York, N.Y.). 340: 711-6. PMID 23539181 DOI: 10.1126/Science.1234150 |
0.321 |
|
| 2013 |
Julien JP, Lee JH, Cupo A, Murin CD, Derking R, Hoffenberg S, Caulfield MJ, King CR, Marozsan AJ, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proceedings of the National Academy of Sciences of the United States of America. 110: 4351-6. PMID 23426631 DOI: 10.1073/Pnas.1217537110 |
0.355 |
|
| 2012 |
Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, ... ... Ward AB, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008 |
0.304 |
|
| 2012 |
Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, et al. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature. 489: 526-32. PMID 22982990 DOI: 10.1038/Nature11414 |
0.31 |
|
| 2012 |
Depetris RS, Julien JP, Khayat R, Lee JH, Pejchal R, Katpally U, Cocco N, Kachare M, Massi E, David KB, Cupo A, Marozsan AJ, Olson WC, Ward AB, Wilson IA, et al. Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers. The Journal of Biological Chemistry. 287: 24239-54. PMID 22645128 DOI: 10.1074/Jbc.M112.371898 |
0.376 |
|
| 2011 |
Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, ... ... Ward AB, et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (New York, N.Y.). 334: 1097-103. PMID 21998254 DOI: 10.1126/Science.1213256 |
0.364 |
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