Tsutomu Sasaki, Ph.D. - Publications

Affiliations: 
2007 University of Virginia, Charlottesville, VA 
Area:
Molecular Biology, Neuroscience Biology

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hosooka T, Hosokawa Y, Matsugi K, Shinohara M, Senga Y, Tamori Y, Aoki C, Matsui S, Sasaki T, Kitamura T, Kuroda M, Sakaue H, Nomura K, Yoshino K, Nabatame Y, et al. The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B axis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32393635 DOI: 10.1073/Pnas.1921015117  0.311
2018 Matsui S, Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O, Suga T, Kobayashi M, Yamanaka A, Harada A, Nakagawa T, Onaka T, Kitamura T. Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice. Nature Communications. 9: 4604. PMID 30389922 DOI: 10.1038/S41467-018-07033-Z  0.3
2018 Gulshan M, Yaku K, Okabe K, Mahmood A, Sasaki T, Yamamoto M, Hikosaka K, Usui I, Kitamura T, Tobe K, Nakagawa T. Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance. Aging Cell. e12798. PMID 29901258 DOI: 10.1111/Acel.12798  0.329
2018 Sasaki T, Numano R, Yokota-Hashimoto H, Matsui S, Kimura N, Takeuchi H, Kitamura T. A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice. Molecular Brain. 11: 28. PMID 29793524 DOI: 10.1186/S13041-018-0372-9  0.316
2017 Fukunaka A, Fukada T, Bhin J, Suzuki L, Tsuzuki T, Takamine Y, Bin BH, Yoshihara T, Ichinoseki-Sekine N, Naito H, Miyatsuka T, Takamiya S, Sasaki T, Inagaki T, Kitamura T, et al. Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression. Plos Genetics. 13: e1006950. PMID 28854265 DOI: 10.1371/Journal.Pgen.1006950  0.314
2017 Iwakoshi-Ukena E, Shikano K, Kondo K, Taniuchi S, Furumitsu M, Ochi Y, Sasaki T, Okamoto S, Bentley GE, Kriegsfeld LJ, Minokoshi Y, Ukena K. Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity. Elife. 6. PMID 28799896 DOI: 10.7554/Elife.28527  0.317
2015 Sasaki T. Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity. Frontiers in Endocrinology. 6: 109. PMID 26236282 DOI: 10.3389/Fendo.2015.00109  0.315
2015 Sasaki T, Kuroko M, Sekine S, Matsui S, Kikuchi O, Susanti VY, Kobayashi M, Tanaka Y, Yuasa T, Kitamura T. Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice. Endocrine Journal. PMID 26096452 DOI: 10.1507/Endocrj.Ej15-0255  0.303
2015 Sasaki T, Hiraga H, Yokota-Hashimoto H, Kitamura T. Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue [Rapid Communication]. Endocrine Journal. 62: 469-73. PMID 25833077 DOI: 10.1507/Endocrj.Ej15-0116  0.336
2014 Kohno D, Lee S, Harper MJ, Kim KW, Sone H, Sasaki T, Kitamura T, Fan G, Elmquist JK. Dnmt3a in Sim1 neurons is necessary for normal energy homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15288-96. PMID 25392496 DOI: 10.1523/Jneurosci.1316-14.2014  0.352
2014 Susanti VY, Sasaki T, Yokota-Hashimoto H, Matsui S, Lee YS, Kikuchi O, Shimpuku M, Kim HJ, Kobayashi M, Kitamura T. Sirt1 rescues the obesity induced by insulin-resistant constitutively-nuclear FoxO1 in POMC neurons of male mice. Obesity (Silver Spring, Md.). 22: 2115-9. PMID 25044690 DOI: 10.1002/Oby.20838  0.338
2014 Yoshino S, Satoh T, Yamada M, Hashimoto K, Tomaru T, Katano-Toki A, Kakizaki S, Okada S, Shimizu H, Ozawa A, Tuchiya T, Ikota H, Nakazato Y, Mori M, Matozaki T, ... Sasaki T, et al. Protection against high-fat diet-induced obesity in Helz2-deficient male mice due to enhanced expression of hepatic leptin receptor. Endocrinology. 155: 3459-72. PMID 25004093 DOI: 10.1210/En.2013-2160  0.351
2014 Sasaki T, Kikuchi O, Shimpuku M, Susanti VY, Yokota-Hashimoto H, Taguchi R, Shibusawa N, Sato T, Tang L, Amano K, Kitazumi T, Kuroko M, Fujita Y, Maruyama J, Lee YS, et al. Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice. Diabetologia. 57: 819-31. PMID 24374551 DOI: 10.1007/S00125-013-3140-5  0.322
2014 Lee YS, Kobayashi M, Kikuchi O, Sasaki T, Yokota-Hashimoto H, Susanti VY, Ido Kitamura Y, Kitamura T. ATF3 expression is induced by low glucose in pancreatic α and β cells and regulates glucagon but not insulin gene transcription. Endocrine Journal. 61: 85-90. PMID 24140652 DOI: 10.1507/Endocrj.Ej13-0383  0.321
2013 Syamsunarno MR, Iso T, Hanaoka H, Yamaguchi A, Obokata M, Koitabashi N, Goto K, Hishiki T, Nagahata Y, Matsui H, Sano M, Kobayashi M, Kikuchi O, Sasaki T, Maeda K, et al. A critical role of fatty acid binding protein 4 and 5 (FABP4/5) in the systemic response to fasting. Plos One. 8: e79386. PMID 24244493 DOI: 10.1371/Journal.Pone.0079386  0.322
2013 Sasaki T, Shimpuku M, Kitazumi T, Hiraga H, Nakagawa Y, Shibata H, Okamatsu-Ogura Y, Kikuchi O, Kim HJ, Fujita Y, Maruyama J, Susanti VY, Yokota-Hashimoto H, Kobayashi M, Saito M, et al. Miglitol prevents diet-induced obesity by stimulating brown adipose tissue and energy expenditure independent of preventing the digestion of carbohydrates. Endocrine Journal. 60: 1117-29. PMID 23995917 DOI: 10.1507/Endocrj.Ej13-0333  0.308
2013 Lee YS, Sasaki T, Kobayashi M, Kikuchi O, Kim HJ, Yokota-Hashimoto H, Shimpuku M, Susanti VY, Ido-Kitamura Y, Kimura K, Inoue H, Tanaka-Okamoto M, Ishizaki H, Miyoshi J, Ohya S, et al. Hypothalamic ATF3 is involved in regulating glucose and energy metabolism in mice. Diabetologia. 56: 1383-93. PMID 23462798 DOI: 10.1007/S00125-013-2879-Z  0.312
2012 Hasegawa K, Kawahara T, Fujiwara K, Shimpuku M, Sasaki T, Kitamura T, Yoshikawa K. Necdin controls Foxo1 acetylation in hypothalamic arcuate neurons to modulate the thyroid axis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5562-72. PMID 22514318 DOI: 10.1523/Jneurosci.0142-12.2012  0.336
2012 Kikuchi O, Kobayashi M, Amano K, Sasaki T, Kitazumi T, Kim HJ, Lee YS, Yokota-Hashimoto H, Kitamura YI, Kitamura T. FoxO1 gain of function in the pancreas causes glucose intolerance, polycystic pancreas, and islet hypervascularization. Plos One. 7: e32249. PMID 22384192 DOI: 10.1371/Journal.Pone.0032249  0.318
2012 Kim HJ, Kobayashi M, Sasaki T, Kikuchi O, Amano K, Kitazumi T, Lee YS, Yokota-Hashimoto H, Susanti VY, Kitamura YI, Nakae J, Kitamura T. Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance. Endocrinology. 153: 659-71. PMID 22186407 DOI: 10.1210/En.2011-1635  0.328
2012 Kitamura T, Sasaki T. Hypothalamic Sirt1 and regulation of food intake Diabetology International. 3: 109-112. DOI: 10.1007/S13340-012-0088-5  0.344
2010 Sasaki T, Kitamura T. Roles of FoxO1 and Sirt1 in the central regulation of food intake. Endocrine Journal. 57: 939-46. PMID 21048357 DOI: 10.1507/Endocrj.K10E-320  0.345
2010 Sasaki T, Kim HJ, Kobayashi M, Kitamura YI, Yokota-Hashimoto H, Shiuchi T, Minokoshi Y, Kitamura T. Induction of hypothalamic Sirt1 leads to cessation of feeding via agouti-related peptide. Endocrinology. 151: 2556-66. PMID 20375183 DOI: 10.1210/En.2009-1319  0.379
2008 Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, Scrable H. Phosphorylation regulates SIRT1 function. Plos One. 3: e4020. PMID 19107194 DOI: 10.1371/Journal.Pone.0004020  0.638
2006 Sasaki T, Maier B, Bartke A, Scrable H. Progressive loss of SIRT1 with cell cycle withdrawal. Aging Cell. 5: 413-22. PMID 16939484 DOI: 10.1111/J.1474-9726.2006.00235.X  0.644
2005 Scrable H, Sasaki T, Maier B. DeltaNp53 or p44: priming the p53 pump. The International Journal of Biochemistry & Cell Biology. 37: 913-9. PMID 15743665 DOI: 10.1016/J.Biocel.2004.11.014  0.607
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