Gerrit J. Koomen - Publications

Affiliations: 
1992-2006 chemistry University of Amsterdam, Amsterdam, Netherlands 
Area:
bio-organic chemistry

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Ghisaidoobe AT, van den Berg RJ, Butt SS, Strijland A, Donker-Koopman WE, Scheij S, van den Nieuwendijk AM, Koomen GJ, van Loevezijn A, Leemhuis M, Wennekes T, van der Stelt M, van der Marel GA, van Boeckel CA, Aerts JM, et al. Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors. Journal of Medicinal Chemistry. 57: 9096-104. PMID 25250725 DOI: 10.1021/jm501181z  0.462
2001 Burm BEA, Blokker P, Jongmans E, Van Kampen E, Wanner MJ, Koomen GJ. Synthesis of xestomanzamines a and b Heterocycles. 55: 495-503. DOI: 10.3987/Com-00-9107  0.364
2000 Deghati PYF, Wanner MJ, Koomen GJ. Regioselective nitration of purine nucleosides: Synthesis of 2- nitroadenosine and 2-nitroinosine Tetrahedron Letters. 41: 1291-1295. DOI: 10.1016/S0040-4039(99)02271-6  0.334
1999 Madre M, Panchenko N, Golbraikh A, Zhuk R, Pandit UK, Geenevasen J, Koomen GJ. Purine nucleoside analogues. 11. An alternative synthesis of N- and O-alkyl derivatives of 9- and 7-[(2-acetoxyethoxy)methyl]-N2-acetylguanine Collection of Czechoslovak Chemical Communications. 64: 685-695. DOI: 10.1135/Cccc19990685  0.56
1999 Barends J, Van Der Linden JB, Van Delft FL, Koomen GJ. Palladium-catalyzed amination of 6-chloropurine. Synthesis of N6- substituted adenosine analogues Nucleosides and Nucleotides. 18: 2121-2126.  0.364
1998 Overkleeft HS, Renkema GH, Neele J, Vianello P, Hung IO, Strijland A, van der Burg AM, Koomen GJ, Pandit UK, Aerts JM. Generation of specific deoxynojirimycin-type inhibitors of the non-lysosomal glucosylceramidase. The Journal of Biological Chemistry. 273: 26522-7. PMID 9756888 DOI: 10.1074/jbc.273.41.26522  0.567
1998 Burm BEA, Meijler MM, Korver J, Wanner MJ, Koomen GJ. Synthesis of the brominated marine alkaloids (±)-arborescidine A, B and C Tetrahedron. 54: 6135-6146. DOI: 10.1016/S0040-4020(98)00306-8  0.307
1997 Wanner MJ, Koomen GJ. Biomimetic synthesis of racemic alkaloids Pharmacochemistry Library. 28: 179-187. DOI: 10.1016/S0165-7208(97)80064-5  0.317
1997 Wanner MJ, Koomen GJ. Biomimetic Synthesis of Nitraria Alkaloids, based on Tetrahydropyridine Synthons Journal of the Indian Chemical Society. 74: 891-895.  0.302
1996 Petra DGI, De Boer RF, Koomen GJ, Meeuwenoord NJ, Kuyl-Yeheskiely E, Van Der Marel GA, Van Boom JH. Synthesis and properties of a fluorescent nucleotide derivative Recueil Des Travaux Chimiques Des Pays-Bas-Journal of the Royal Netherlands. 115: 99-102. DOI: 10.1002/Recl.19961150117  0.39
1995 Madre M, Geita L, Zhuk R, Koomen GJ. Purine nucleoside analogues. 7. 9-[2-(Alkylthio)ethoxymethyl] derivatives of adenine, hypoxanthine and guanine Chinese Pharmaceutical Journal. 47: 469-481.  0.308
1995 Wanner MJ, Koomen GJ. Biomimetic synthesis of nitraramine The Journal of Organic Chemistry. 60: 5634-5637.  0.301
1994 Wanner MJ, Koomen GJ. Biomimetic synthesis of nazlinin and nitrarine Pure and Applied Chemistry. 66: 2239-2242. DOI: 10.1351/pac199466102239  0.301
1994 Boogaard AT, Pandit UK, Koomen GJ. Ring D modifications of ellipticine. Part 2. Chlorination of ellipticine via its N-oxide and synthesis and selective acetylation of 5,6,11-trimethyl-5H-benzo[b]carbazole. Tetrahedron. 50: 4811-4828. DOI: 10.1016/S0040-4020(01)85018-3  0.539
1992 Hartgers WA, De Boer RF, Wanner MJ, Koomen GJ. A potential suicide inhibitor of adenylosuccinate lyase Nucleosides and Nucleotides. 11: 1325-1332. DOI: 10.1080/07328319208021176  0.319
1992 Koomen GJ, Provoost LM, Van Maarschalkerwaart DAH, Willard NP. Synthesis of an acyclic analogue of azidothymidine Nucleosides and Nucleotides. 11: 1297-1303. DOI: 10.1080/07328319208021174  0.337
1992 Plug JPM, Koomen GJ, Pandit UK. An expedient synthesis of 9-hydroxyellipticine Synthesis. 1221-1222. DOI: 10.1055/S-1992-26342  0.517
1992 Vloon WJ, van den Bos JC, Koomen GJ, Pandit UK. Synthesis of ring C modified sesbanimide analogues Tetrahedron. 48: 8317-8328. DOI: 10.1016/S0040-4020(01)80499-3  0.537
1992 Plug JPM, Koomen GJ, Pandit UK. Sythesis of novel annulated ellipticines via Claisen rearrangement reactions Tetrahedron Letters. 33: 2179-2182. DOI: 10.1016/0040-4039(92)88171-Z  0.577
1991 Wanner MJ, Koomen GJ. Biomimetic synthesis of quinolizidine alkaloids Tetrahedron. 47: 8431-8442. DOI: 10.1016/S0040-4020(01)96184-8  0.314
1991 van den Bos JC, Vloon WJ, Koomen GJ, Pandit UK. Synthesis of acyclic analogues of sesbanimides A and B Tetrahedron. 47: 6787-6794. DOI: 10.1016/S0040-4020(01)82330-9  0.562
1990 Van Maarschalkerwaart DAH, Willard NP, Koomen GJ. Carbocyclic nucleoside analogues. Synthesis and properties of 1-(4-hydroxymethyl-2-cyclopenten-1-yl)-thymine Nucleosides and Nucleotides. 9: 787-791. DOI: 10.1080/15257779008043144  0.321
1989 Langendoen A, Plug JPM, Koomen GJ, Pandit UK. Regiospecific C-9 substitution of ellipticine derivatives Tetrahedron. 45: 1759-1762. DOI: 10.1016/S0040-4020(01)80040-5  0.514
1988 Wanner MJ, Koomen GJ. 2-Substituted Glutarimides via Preformed Wittig Reagents Synthesis. 1988: 325-327. DOI: 10.1055/S-1988-27558  0.304
1988 Langendoen A, Koomen GJ, Pandit UK. An approach to novel ellipticine glycosides Tetrahedron. 44: 3627-3631. DOI: 10.1016/S0040-4020(01)85992-5  0.546
1988 WANNER MJ, KOOMEN G. ChemInform Abstract: 2-Substituted Glutarimides via Preformed Wittig Reagents. Cheminform. 19. DOI: 10.1002/CHIN.198833239  0.303
1987 Langendoen A, Koomen GJ, Pandit UK. A new approach to C-9 hydroxylation of N(6)-substituted ellipticine Heterocycles. 26: 91-94. DOI: 10.3987/R-1987-01-0091  0.495
1987 Langendoen A, Koomen GJ, Pandit UK. Side-chain substitution of 6-methylellipticine approach to a new class of ellipticine derivatives Heterocycles. 26: 69-73. DOI: 10.3987/R-1987-01-0069  0.468
1987 Wanner MJ, Willard NP, Koomen GJ, Pandit UK. Stereospecific synthesis of (+)- and (-)-sesbanimide A Tetrahedron. 43: 2549-2556. DOI: 10.1016/S0040-4020(01)81662-8  0.541
1986 Wijsmuller WFA, Wanner MJ, Koomen GJ, Pandit UK. Pyridocarbazole alkaloids. Synthesis of olivacine and ellipticine analogues Heterocycles. 24: 1795-1797. DOI: 10.1002/Chin.198647359  0.566
1986 Koomen GJ, Wolschrijn H, van Rhijn JBM, Wanner MJ, Pandit UK. Synthesis of 5-fluoro-3-(2-tetrahydrofuryl)-6-vinyluracil. Design of a 5-fu-derivative with extended conjugation Heterocycles. 24: 939-941. DOI: 10.1002/Chin.198642214  0.519
1986 Wanner MJ, Willard NP, Koomen GJ, Pandit UK. Synthesis of (7R,8S,9R,10S,11S)-sesbanimide A Journal of the Chemical Society - Series Chemical Communications. 396-397. DOI: 10.1002/Chin.198634331  0.418
1985 Koomen GJ, van Rhijn JBMv, Pandit UK. Non-glycosidic derivatives of 5-fluorouracil Nucleosides and Nucleotides. 4: 215-216. DOI: 10.1080/07328318508077858  0.476
1985 Odijk WM, Koomen GJ. Fluorescent nucleoside analogues. Synthesis of fluorescent pyrido[2,1-i]purines, and their corresponding ribosides Tetrahedron. 41: 1893-1904. DOI: 10.1016/S0040-4020(01)96552-4  0.443
1984 WANNER MJ, KOOMEN G, PANDIT UK. ChemInform Abstract: STUDIES IN THE STEREOSPECIFIC SYNTHESIS OF SESBANIMIDE. SYNTHESIS OF 4-SACCHARIDALGLUTARIMIDES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198448332  0.557
1983 Wanner MJ, Koomen GJ, Pandit UK. Inter- and intramolecular addition of ester anions to nicotinium salts. A facile approach to nauclefine and ellipticine derivatives Tetrahedron. 39: 3673-3681. DOI: 10.1016/S0040-4020(01)88606-3  0.62
1983 WANNER MJ, KOOMEN G, PANDIT UK. ChemInform Abstract: A CONVENIENT SYNTHESIS OF 6-METHYLELLIPTICINE AND 6-METHYLOLIVACINE Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198322343  0.559
1982 Wanner MJ, Koomen GJ, Pandit UK. Synthesis of polynuclear heterocycles via the reaction of α-ester carbanions with quaternized nicotinamide salts. A facile stereoselective synthesis of sesbanine Tetrahedron. 38: 2741-2748. DOI: 10.1016/0040-4020(82)80032-X  0.615
1982 WANNER MJ, KOOMEN G, PANDIT UK. ChemInform Abstract: A New Approach to Ellipticine Analogues; Synthesis of 11-Hydroxy-5,6-dimethyl-pyrido[4,3-b]carbazole. Chemischer Informationsdienst. 13. DOI: 10.1002/Chin.198233202  0.542
1980 Wanner MJ, Hageman JJ, Koomen GJ, Pandit UK. Potential carcinostatics. 4. Synthesis and biological properties of erythro- and threo-beta-fluoroaspartic acid and erythro-beta-fluoroasparagine. Journal of Medicinal Chemistry. 23: 85-7. PMID 7359517 DOI: 10.1021/Jm00175A017  0.548
1980 Wanner MJ, Van Wijk EM, Koomen GJ, Pandit UK. Potential carcinostatics. V. Synthesis and properties of potential inhibitors of the adenylosuccinate synthetase and adenylosuccinate lyase system Recueil Des Travaux Chimiques Des Pays Bas. 99: 20-23. DOI: 10.1002/Recl.19780970711  0.609
1980 Wanner MJ, Hageman JJM, Koomen GJ, Pandit UK. POTENTIAL CARCINOSTATICS. 4. SYNTHESIS AND BIOLOGICAL PROPERTIES OF ERYTHRO- AND THREO-β-FLUOROASPARTIC ACID AND ERYTHRO-β-FLUOROASPARAGINE Cheminform. 11. DOI: 10.1002/Chin.198024111  0.503
1979 ODIJK WM, WANNER MJ, KOOMEN GJ, PANDIT UK. ChemInform Abstract: POTENTIAL CARCINOSTATIC AGENTS. PART III. PSEUDO-GLYCOSIDIC DERIVATIVES OF 5-FLUOROURACIL Chemischer Informationsdienst. 10. DOI: 10.1002/Chin.197909223  0.515
1978 Wanner MJ, Hageman JJM, Koomen GJ, Pandit UK. Potential Carcinostatics. Part Ii. Synthesis And Properties Of Potential Inhibitors Of The Adenylosuccinate Synthetase And Adenylosuccinate Lyase Systems Cheminform. 11. DOI: 10.1002/Chin.197843246  0.521
1978 HAGEMAN JJM, WANNER MJ, KOOMEN GJ, PANDIT UK. ChemInform Abstract: POTENTIAL CARCINOSTATICS. SYNTHESIS AND BIOLOGICAL PROPERTIES OF D- AND L-β,β-DIFLUOROASPARTIC ACID AND β,β-DIFLUOROASPARAGINE Chemischer Informationsdienst. 9. DOI: 10.1002/Chin.197816128  0.489
1978 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGS. XVIII. RING EXPANSION OF URIDINE HALOCARBENE ADDUCTS. SYNTHESIS OF DIAZEPINE NUCLEOSIDES Chemischer Informationsdienst. 9. DOI: 10.1002/chin.197802343  0.341
1978 Wanner MJ, Hageman JJM, Koomen GJ, Pandit UK. Potential carcinostatics. Synthesis and properties of potential inhibitors of the adenylosuccinate synthetase and adenylosuccinate lyase systems Recueil Des Travaux Chimiques Des Pays Bas. 97: 211-214.  0.479
1977 Hageman JJ, Wanner MJ, Koomen GJ, Pandit UK. Potential carcinostatics. Synthesis and biological properties of d- and 1-beta,beta-difluoroaspartic acid and beta,beta-difluoroasparagine. Journal of Medicinal Chemistry. 20: 1677-9. PMID 592334 DOI: 10.1021/Jm00222A029  0.471
1977 Thiellier HPM, Koomen GJ, Pandit UK. Unconventional nucleotide analogues1 1 Part XV. H.P.M Thiellier, G.J. Koomen and U.K. Pandit, Heterocycles 5, 19 (1976). Reaction of carbenes with uracil and uridine derivatives Tetrahedron. 33: 1493-1500. DOI: 10.1016/0040-4020(77)88011-3  0.587
1977 Thiellier HPM, Koomen GJ, Pandit UK. Unconventional nucleotide analogues-XVIII1 1 Part XVII. H.P.M. Thiellier, G.J. Koomen and U.K. Pandit, Tetrahedron 33, 2603 (1977). Ring expansion of uridine halocarbene adducts. Synthesis of diazepine nucleosides Tetrahedron. 33: 2609-2612. DOI: 10.1016/0040-4020(77)80087-2  0.603
1977 Thiellier HPM, Koomen GJ, Pandit UK. Unconventional nucleotide analogues-XVII1 1 Part XVI. H.P.M. Thiellier, G.J. Koomen and U.K. Pandit, Tetrahedron 33, 1493 (1977). Ring-transformations of uracil dihalocarbene adducts Tetrahedron. 33: 2603-2607. DOI: 10.1016/0040-4020(77)80086-0  0.585
1977 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGS. XV. NOVEL BASE-MODIFIED NUCLEOSIDES Chemischer Informationsdienst. 8: no-no. DOI: 10.1002/Chin.197717341  0.539
1976 THIELLIER HPM, KOOMEN GJ, PANDIT UK. ChemInform Abstract: TRANSFORMATIONS OF 1,3-DISUBSTITUTED URACIL-CARBENE ADDUCTS. RING EXPANSION TO 1,3-DIAZEPINE DERIVATIVES Chemischer Informationsdienst. 7: no-no. DOI: 10.1002/Chin.197603227  0.559
1974 THIELLIER HPM, BURG AMVD, KOOMEN GJ, PANDIT UK. ChemInform Abstract: REACTION OF CARBENES WITH 1,3-DISUBSTITUTED URACIL DERIVATIVES Chemischer Informationsdienst. 5: no-no. DOI: 10.1002/Chin.197451349  0.55
1973 Koomen GJ, Pandit UK. Unconventional nucleotide analogues. IX. N-substituted 3-(pyrimidin-1-yl) pyrrolidin-2-ones. Journal of the Chemical Society. Perkin Transactions 1. 17: 1929-33. PMID 4799178 DOI: 10.1039/P19730001929  0.57
1973 Koomen GJ, Kroon AP, Mas Cabré FR, Goores AP, Peereboom R, Pandit UK. Unconventional nucleotide analogues. Part X. Synthesis of N-substituted 3-(Adenin-9-yl)pyrrolidin-2-ones Journal of the Chemical Society, Perkin Transactions 1. 1934-1940. PMID 4363162 DOI: 10.1039/P19730001934  0.599
1973 KOOMEN GJ, PANDIT UK. ChemInform Abstract: UNCONVENTIONAL NUCLEOTIDE ANALOGUES PART 9, N-SUBSTITUTED 3-(PYRIMIDIN-1-YL)-PYRROLIDIN-2-ONES Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/chin.197349468  0.546
1971 Koomen GJ, Kroon AP, Goores AP, Pandit UK. Non-Sacccfaridal Nucleoside and Hucleotide Analocuses Synthetic Communications. 1: 41-45. DOI: 10.1080/00397917108081615  0.421
1971 KOOMEN GJ, KROON AP, GOORES AP, PANDIT UK. ChemInform Abstract: ZUCKERFREIE NUCLEOSID- UND NUCLEOTID-ANALOGA Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/Chin.197139334  0.519
1969 Nollet AJH, Koomen GJ, Grose WFA, Pandit UK. Application of NMR spectroscopy in distinguishing between N1- and N3-substituted 2,4-dioxo-1,2,3,4,-tetrahydropyrimidines. Tetrahedron Letters. 10: 4607-4608. DOI: 10.1016/S0040-4039(01)88762-1  0.467
1967 Pandit UK, de Jonge K, Koomen GJ, Huisman HO. Heterocyclic steroids IX. A Convenient Synthesis of 14-Aza-11-Keto Steroids Tetrahedron Letters. 8: 3529-3533.  0.688
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