Danny D. Shen - Publications

Affiliations: 
1975-1979 University of Kansas Medical Center, Kansas City, KS, United States 
 1979-1984 State University of New York, Buffalo, Buffalo, NY, United States 
 1984- University of Washington, Seattle, Seattle, WA 
Area:
Pharmacology, Neuroscience Biology
Website:
http://www.springer.com/biomed/pharmacology+%26+toxicology?SGWID=0-132-6-648109-0

168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 McAdams RM, Pak D, Lalovic B, Phillips B, Shen DD. Dexmedetomidine Pharmacokinetics in Neonates with Hypoxic-Ischemic Encephalopathy Receiving Hypothermia. Anesthesiology Research and Practice. 2020: 2582965. PMID 32158472 DOI: 10.1155/2020/2582965  1
2018 Cheng SL, Li X, Lehmler HJ, Phillips B, Shen D, Cui JY. Gut Microbiota Modulates Interactions Between Polychlorinated Biphenyls and Bile Acid Homeostasis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 166: 269-287. PMID 30496569 DOI: 10.1093/toxsci/kfy208  1
2018 Chapron BD, Chapron A, Phillips B, Okoli MC, Shen DD, Kelly EJ, Himmelfarb J, Thummel KE. Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system. Altex. PMID 29999169 DOI: 10.14573/altex.1803161  1
2017 Liao MZ, Gao C, Shireman LM, Phillips B, Risler LJ, Neradugomma NK, Choudhari P, Prasad B, Shen DD, Mao Q. P-gp/ABCB1 Exerts Differential Impacts On Brain and Fetal Exposure to Norbuprenorphine. Pharmacological Research. PMID 28111265 DOI: 10.1016/j.phrs.2017.01.018  1
2015 Yeung CK, Billings FT, Claessens AJ, Roshanravan B, Linke L, Sundell MB, Ahmad S, Shao B, Shen DD, Ikizler TA, Himmelfarb J. Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress. Bmc Nephrology. 16: 183. PMID 26531095 DOI: 10.1186/s12882-015-0178-2  1
2015 Ryu RJ, Eyal S, Easterling TR, Caritis SN, Venkataraman R, Hankins G, Rytting E, Thummel K, Kelly EJ, Risler L, Phillips B, Honaker MT, Shen DD, Hebert MF. Pharmacokinetics of metoprolol during pregnancy and lactation. Journal of Clinical Pharmacology. PMID 26461463 DOI: 10.1002/jcph.631  1
2015 Vogel KR, Ainslie GR, Phillips B, Arning E, Bottiglieri T, Shen DD, Gibson KM. Physiological Competition of Brain Phenylalanine Accretion: Initial Pharmacokinetic Analyses of Aminoisobutyric and Methylaminoisobutyric Acids in Pah(enu2-/-) Mice. Molecular Genetics and Metabolism Reports. 3: 80-87. PMID 26120559 DOI: 10.1016/j.ymgmr.2015.03.009  1
2015 Claessens AJ, Yeung CK, Risler LJ, Phillips BR, Himmelfarb J, Shen DD. Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects. Annals of Clinical Biochemistry. PMID 26056391 DOI: 10.1177/0004563215593097  1
2015 Chapron B, Risler L, Phillips B, Collins C, Thummel K, Shen D. Reversible, time-dependent inhibition of CYP3A-mediated metabolism of midazolam and tacrolimus by telaprevir in human liver microsomes. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, SociéTé Canadienne Des Sciences Pharmaceutiques. 18: 101-11. PMID 25877445  1
2015 Chan LN, Lin YS, Tay-Sontheimer JC, Trawick D, Oelschlager BK, Flum DR, Patton KK, Shen DD, Horn JR. Proximal Roux-en-Y gastric bypass alters drug absorption pattern but not systemic exposure of CYP3A4 and P-glycoprotein substrates. Pharmacotherapy. 35: 361-9. PMID 25757445 DOI: 10.1002/phar.1560  1
2015 McAdams RM, McPherson RJ, Kapur R, Phillips B, Shen DD, Juul SE. Dexmedetomidine reduces cranial temperature in hypothermic neonatal rats. Pediatric Research. 77: 772-8. PMID 25751572 DOI: 10.1038/pr.2015.45  1
2015 Vogel KR, Ainslie GR, Phillips B, Arning E, Bottiglieri T, Shen DD, Gibson KM. Physiological competition of brain phenylalanine accretion: Initial pharmacokinetic analyses of aminoisobutyric and methylaminoisobutyric acids in Pahenu2 -/- mice Molecular Genetics and Metabolism Reports. 3: 80-87. DOI: 10.1016/j.ymgmr.2015.03.009  1
2014 Shuster DL, Risler LJ, Prasad B, Calamia JC, Voellinger JL, Kelly EJ, Unadkat JD, Hebert MF, Shen DD, Thummel KE, Mao Q. Identification of CYP3A7 for glyburide metabolism in human fetal livers. Biochemical Pharmacology. 92: 690-700. PMID 25450675 DOI: 10.1016/j.bcp.2014.09.025  1
2014 Shuster DL, Risler LJ, Liang CK, Rice KM, Shen DD, Hebert MF, Thummel KE, Mao Q. Maternal-fetal disposition of glyburide in pregnant mice is dependent on gestational age. The Journal of Pharmacology and Experimental Therapeutics. 350: 425-34. PMID 24898265 DOI: 10.1124/jpet.114.213470  1
2014 Roth GA, Gillespie CW, Mokdad AA, Shen DD, Fleming DW, Stergachis A, Murray CJ, Mokdad AH. Aspirin use and knowledge in the community: a population- and health facility based survey for measuring local health system performance. Bmc Cardiovascular Disorders. 14: 16. PMID 24507089 DOI: 10.1186/1471-2261-14-16  1
2014 Crews KR, Gaedigk A, Dunnenberger HM, Leeder JS, Klein TE, Caudle KE, Haidar CE, Shen DD, Callaghan JT, Sadhasivam S, Prows CA, Kharasch ED, Skaar TC. Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 Update Clinical Pharmacology and Therapeutics. 95: 376-382. PMID 24458010 DOI: 10.1038/clpt.2013.254  1
2014 Yeung CK, Shen DD, Thummel KE, Himmelfarb J. Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport. Kidney International. 85: 522-8. PMID 24132209 DOI: 10.1038/ki.2013.399  1
2013 Kelly EJ, Wang Z, Voellinger JL, Yeung CK, Shen DD, Thummel KE, Zheng Y, Ligresti G, Eaton DL, Muczynski KA, Duffield JS, Neumann T, Tourovskaia A, Fauver M, Kramer G, et al. Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system. Stem Cell Research & Therapy. 4: S17. PMID 24564863 DOI: 10.1186/scrt378  1
2013 Dodds M, Chow V, Markus R, Pérez-Ruixo JJ, Shen D, Gibbs M. The use of pharmacometrics to optimize biosimilar development. Journal of Pharmaceutical Sciences. 102: 3908-14. PMID 24027111 DOI: 10.1002/jps.23697  1
2013 Kantor ED, Ulrich CM, Owen RW, Schmezer P, Neuhouser ML, Lampe JW, Peters U, Shen DD, Vaughan TL, White E. Specialty supplement use and biologic measures of oxidative stress and DNA damage. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 22: 2312-22. PMID 23917455 DOI: 10.1158/1055-9965.EPI-13-0470  1
2013 Kantor ED, Lampe JW, Peters U, Shen DD, Vaughan TL, White E. Use of glucosamine and chondroitin supplements and risk of colorectal cancer. Cancer Causes & Control : Ccc. 24: 1137-46. PMID 23529472 DOI: 10.1007/s10552-013-0192-2  1
2013 Zheng S, Easterling TR, Hays K, Umans JG, Miodovnik M, Clark S, Calamia JC, Thummel KE, Shen DD, Davis CL, Hebert MF. Tacrolimus placental transfer at delivery and neonatal exposure through breast milk. British Journal of Clinical Pharmacology. 76: 988-96. PMID 23528073 DOI: 10.1111/bcp.12122  1
2013 Zheng S, Tasnif Y, Hebert MF, Davis CL, Shitara Y, Calamia JC, Lin YS, Shen DD, Thummel KE. CYP3A5 gene variation influences cyclosporine A metabolite formation and renal cyclosporine disposition. Transplantation. 95: 821-7. PMID 23354298 DOI: 10.1097/TP.0b013e31827e6ad9  1
2013 Hebert MF, Zheng S, Hays K, Shen DD, Davis CL, Umans JG, Miodovnik M, Thummel KE, Easterling TR. Interpreting tacrolimus concentrations during pregnancy and postpartum. Transplantation. 95: 908-15. PMID 23274970 DOI: 10.1097/TP.0b013e318278d367  1
2013 Wang Z, Lin YS, Dickmann LJ, Poulton EJ, Eaton DL, Lampe JW, Shen DD, Davis CL, Shuhart MC, Thummel KE. Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalacia. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1101-16. PMID 23212742 DOI: 10.1002/jbmr.1839  1
2013 Poulton EJ, Levy L, Lampe JW, Shen DD, Tracy J, Shuhart MC, Thummel KE, Eaton DL. Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo. Toxicology and Applied Pharmacology. 266: 122-31. PMID 23153560 DOI: 10.1016/j.taap.2012.10.029  1
2012 Zheng S, Tasnif Y, Hebert MF, Davis CL, Shitara Y, Calamia JC, Lin YS, Shen DD, Thummel KE. Measurement and compartmental modeling of the effect of CYP3A5 gene variation on systemic and intrarenal tacrolimus disposition. Clinical Pharmacology and Therapeutics. 92: 737-45. PMID 23073208 DOI: 10.1038/clpt.2012.175  1
2012 Zheng S, Easterling TR, Umans JG, Miodovnik M, Calamia JC, Thummel KE, Shen DD, Davis CL, Hebert MF. Pharmacokinetics of tacrolimus during pregnancy. Therapeutic Drug Monitoring. 34: 660-70. PMID 23007747 DOI: 10.1097/FTD.0b013e3182708edf  1
2012 Bell GA, Kantor ED, Lampe JW, Shen DD, White E. Use of glucosamine and chondroitin in relation to mortality. European Journal of Epidemiology. 27: 593-603. PMID 22828954 DOI: 10.1007/s10654-012-9714-6  1
2012 Jimenez N, Anderson GD, Shen DD, Nielsen SS, Farin FM, Seidel K, Lynn AM. Is ethnicity associated with morphine's side effects in children? Morphine pharmacokinetics, analgesic response, and side effects in children having tonsillectomy. Paediatric Anaesthesia. 22: 669-75. PMID 22486937 DOI: 10.1111/j.1460-9592.2012.03844.x  1
2012 Suresh MV, Wagner MC, Rosania GR, Stringer KA, Min KA, Risler L, Shen DD, Georges GE, Reddy AT, Parkkinen J, Reddy RC. Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury American Journal of Respiratory Cell and Molecular Biology. 47: 280-287. PMID 22312018 DOI: 10.1165/rcmb.2011-0175OC  1
2012 Crews KR, Gaedigk A, Dunnenberger HM, Klein TE, Shen DD, Callaghan JT, Kharasch ED, Skaar TC. Clinical pharmacogenetics implementation consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype Clinical Pharmacology and Therapeutics. 91: 321-326. PMID 22205192 DOI: 10.1038/clpt.2011.287  1
2010 Ho BE, Shen DD, McCune JS, Bui T, Risler L, Yang Z, Ho RJ. Effects of Garlic on Cytochromes P450 2C9- and 3A4-Mediated Drug Metabolism in Human Hepatocytes. Scientia Pharmaceutica. 78: 473-81. PMID 20936048 DOI: 10.3797/scipharm.1002-11  1
2010 Choueiter NF, Olson AK, Shen DD, Portman MA. Prospective open-label trial of etanercept as adjunctive therapy for kawasaki disease. The Journal of Pediatrics. 157: 960-966.e1. PMID 20667551 DOI: 10.1016/j.jpeds.2010.06.014  1
2010 Claessens AJ, Risler LJ, Eyal S, Shen DD, Easterling TR, Hebert MF. CYP2D6 mediates 4-hydroxylation of clonidine in vitro: implication for pregnancy-induced changes in clonidine clearance. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1393-6. PMID 20570945 DOI: 10.1124/dmd.110.033878  1
2010 Eyal S, Easterling TR, Carr D, Umans JG, Miodovnik M, Hankins GD, Clark SM, Risler L, Wang J, Kelly EJ, Shen DD, Hebert MF. Pharmacokinetics of metformin during pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 833-40. PMID 20118196 DOI: 10.1124/dmd.109.031245  1
2010 Yeung CK, Zhao P, Shen DD, Thummel KE. Drug disposition and drug-drug interactions: Importance of first-pass metabolism in gut and liver Enzyme- and Transporter-Based Drug-Drug Interactions: Progress and Future Challenges. 415-435. DOI: 10.1007/978-1-4419-0840-7_17  1
2010 Shen DD. Ideas know no borders Pharmaceutical Technology. 34: 12.  1
2009 Salinger DH, Shen DD, Thummel K, Wittkowsky AK, Vicini P, Veenstra DL. Pharmacogenomic trial design: use of a PK/PD model to explore warfarin dosing interventions through clinical trial simulation. Pharmacogenetics and Genomics. 19: 965-71. PMID 19881396 DOI: 10.1097/FPC.0b013e3283333b80  1
2009 Cherrier MM, Amory JK, Ersek M, Risler L, Shen DD. Comparative cognitive and subjective side effects of immediate-release oxycodone in healthy middle-aged and older adults. The Journal of Pain : Official Journal of the American Pain Society. 10: 1038-50. PMID 19729346 DOI: 10.1016/j.jpain.2009.03.017  1
2009 Li M, Andrew MA, Wang J, Salinger DH, Vicini P, Grady RW, Phillips B, Shen DD, Anderson GD. Effects of cranberry juice on pharmacokinetics of beta-lactam antibiotics following oral administration. Antimicrobial Agents and Chemotherapy. 53: 2725-32. PMID 19398645 DOI: 10.1128/AAC.00774-08  1
2009 Woodahl EL, Crouthamel MH, Bui T, Shen DD, Ho RJ. MDR1 (ABCB1) G1199A (Ser400Asn) polymorphism alters transepithelial permeability and sensitivity to anticancer agents. Cancer Chemotherapy and Pharmacology. 64: 183-8. PMID 19123050 DOI: 10.1007/s00280-008-0906-4  1
2009 Buchanan ML, Easterling TR, Carr DB, Shen DD, Risler LJ, Nelson WL, Mattison DR, Hebert MF. Clonidine pharmacokinetics in pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 702-5. PMID 19116263 DOI: 10.1124/dmd.108.024984  1
2007 Anderson GD, Shen DD. Where is the evidence that p-glycoprotein limits brain uptake of antiepileptic drug and contributes to drug resistance in epilepsy? Epilepsia. 48: 2372-4. PMID 18088270 DOI: 10.1111/j.1528-1167.2007.01260_3.x  1
2007 Chen Y, Kuehl GE, Bigler J, Rimorin CF, Schwarz Y, Shen DD, Lampe JW. UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin. Pharmacogenetics and Genomics. 17: 571-9. PMID 17622933 DOI: 10.1097/01.fpc.0000236339.79916.07  1
2007 Huang W, Kalhorn TF, Baillie M, Shen DD, Thummel KE. Determination of free and total cortisol in plasma and urine by liquid chromatography-tandem mass spectrometry. Therapeutic Drug Monitoring. 29: 215-24. PMID 17417077 DOI: 10.1097/FTD.0b013e31803d14c0  1
2007 Andrew MA, Easterling TR, Carr DB, Shen D, Buchanan ML, Rutherford T, Bennett R, Vicini P, Hebert MF. Amoxicillin pharmacokinetics in pregnant women: modeling and simulations of dosage strategies. Clinical Pharmacology and Therapeutics. 81: 547-56. PMID 17329990 DOI: 10.1038/sj.clpt.6100126  1
2007 Kornblau SM, Banker DE, Stirewalt D, Shen D, Lemker E, Verstovsek S, Estrov Z, Faderl S, Cortes J, Beran M, Jackson CE, Chen W, Estey E, Appelbaum FR. Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study. Blood. 109: 2999-3006. PMID 17158228 DOI: 10.1182/blood-2006-08-044446  1
2006 Salinger DH, McCune JS, Ren AG, Shen DD, Slattery JT, Phillips B, McDonald GB, Vicini P. Real-time dose adjustment of cyclophosphamide in a preparative regimen for hematopoietic cell transplant: a Bayesian pharmacokinetic approach. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4888-98. PMID 16914577 DOI: 10.1158/1078-0432.CCR-05-2079  1
2006 Lalovic B, Kharasch E, Hoffer C, Risler L, Liu-Chen LY, Shen DD. Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites. Clinical Pharmacology and Therapeutics. 79: 461-79. PMID 16678548 DOI: 10.1016/j.clpt.2006.01.009  1
2006 Johns DO, Daniell WE, Shen DD, Kalman DA, Dills RL, Morgan MS. Ethanol-induced increase in the metabolic clearance of 1,1,1-trichloroethane in human volunteers. Toxicological Sciences : An Official Journal of the Society of Toxicology. 92: 61-70. PMID 16638923 DOI: 10.1093/toxsci/kfj210  1
2006 Dai Y, Hebert MF, Isoherranen N, Davis CL, Marsh C, Shen DD, Thummel KE. Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 836-47. PMID 16501005 DOI: 10.1124/dmd.105.008680  1
2006 Li M, Anderson GD, Phillips BR, Kong W, Shen DD, Wang J. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 547-55. PMID 16434549 DOI: 10.1124/dmd.105.006791  1
2005 Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJ. MDR1 G1199A polymorphism alters permeability of HIV protease inhibitors across P-glycoprotein-expressing epithelial cells. Aids (London, England). 19: 1617-25. PMID 16184031  1
2005 Burbacher TM, Shen DD, Liberato N, Grant KS, Cernichiari E, Clarkson T. Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal. Environmental Health Perspectives. 113: 1015-21. PMID 16079072 DOI: 10.1289/ehp.7712  1
2005 Szot P, White SS, Shen DD, Anderson GD. Valproic acid, but not lamotrigine, suppresses seizure-induced c-fos and c-Jun mRNA expression. Brain Research. Molecular Brain Research. 135: 285-9. PMID 15857691 DOI: 10.1016/j.molbrainres.2004.11.011  1
2005 McCune JS, Risler LJ, Phillips BR, Thummel KE, Blough D, Shen DD. Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1074-81. PMID 15821045 DOI: 10.1124/dmd.104.002279  1
2004 Yang Z, Horn M, Wang J, Shen DD, Ho RJ. Development and characterization of a recombinant madin-darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRP1). The Aaps Journal. 6: 77-85. PMID 18465260 DOI: 10.1208/ps060108  1
2004 McConnachie LA, Bodor M, Phillips B, Kelly EJ, Shen DD, Ho RJ. An RT-PCR-based strategy to estimate full-length CYP2D6 mRNA copy number. Genetic Testing. 8: 313-8. PMID 15727256  1
2004 Shen DD, Artru AA, Adkison KK. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics. Advanced Drug Delivery Reviews. 56: 1825-57. PMID 15381336 DOI: 10.1016/j.addr.2004.07.011  1
2004 Burbacher TM, Grant KS, Shen DD, Sheppard L, Damian D, Ellis S, Liberato N. Chronic maternal methanol inhalation in nonhuman primates (Macaca fascicularis): reproductive performance and birth outcome. Neurotoxicology and Teratology. 26: 639-50. PMID 15315813 DOI: 10.1016/j.ntt.2004.06.001  1
2004 Yang Z, Horn M, Wang J, Shen DD, Ho RJ. Development and characterization of a recombinant Madin-Darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRP1). Aaps Pharmsci. 6: E8. PMID 15198509 DOI: 10.1208/ps060108  1
2004 Bowdle TA, Even A, Shen DD, Swardstrom M. Methadone for the induction of anesthesia: plasma histamine concentration, arterial blood pressure, and heart rate. Anesthesia and Analgesia. 98: 1692-7, table of con. PMID 15155330  1
2004 Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJ. Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein. The Journal of Pharmacology and Experimental Therapeutics. 310: 1199-207. PMID 15100388 DOI: 10.1124/jpet.104.065383  1
2004 Gibbs JP, Adeyeye MC, Yang Z, Shen DD. Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport. Epilepsy Research. 58: 53-66. PMID 15066675 DOI: 10.1016/j.eplepsyres.2003.12.008  1
2004 McConnachie L, Bodor M, Kowdley K, Levy A, Tung B, Thummel K, Phillips B, Bajpai M, Chi V, Esmay JD, Shen DD, Ho RJ. Human liver cytochrome P450 2D6 genotype, full-length messenger ribonucleic acid, and activity assessed with a novel cytochrome P450 2D6 substrate. Clinical Pharmacology and Therapeutics. 75: 282-97. PMID 15060507 DOI: 10.1016/j.clpt.2003.12.003  1
2004 Lalovic B, Phillips B, Risler LL, Howald W, Shen DD. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 447-54. PMID 15039299 DOI: 10.1124/dmd.32.4.447  1
2004 Burbacher TM, Shen DD, Lalovic B, Grant KS, Sheppard L, Damian D, Ellis S, Liberato N. Chronic maternal methanol inhalation in nonhuman primates (Macaca fascicularis): exposure and toxicokinetics prior to and during pregnancy. Neurotoxicology and Teratology. 26: 201-21. PMID 15019954 DOI: 10.1016/j.ntt.2003.10.003  1
2004 Yang Z, Horn M, Wang J, Shen DD, Ho RJY. Development and characterization of a recombinant Madin-Darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRPl) Aaps Journal. 6.  1
2004 Ho RJY, Shen DD. Preface Current Drug Metabolism. 5.  1
2003 McConnachie LA, Phillips B, Bajpai M, Shen DD, Ho RJ. Only truncated, not complete cytochrome p450 2D6 RNA transcript and no detectable enzyme activity are expressed in human lymphocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1103-7. PMID 12920165 DOI: 10.1124/dmd.31.9.1103  1
2003 Bernards CM, Shen DD, Sterling ES, Adkins JE, Risler L, Phillips B, Ummenhofer W. Epidural, cerebrospinal fluid, and plasma pharmacokinetics of epidural opioids (part 2): effect of epinephrine. Anesthesiology. 99: 466-75. PMID 12883421 DOI: 10.1097/00000542-200308000-00030  1
2003 Bernards CM, Shen DD, Sterling ES, Adkins JE, Risler L, Phillips B, Ummenhofer W. Epidural, cerebrospinal fluid, and plasma pharmacokinetics of epidural opioids (part 1): differences among opioids. Anesthesiology. 99: 455-65. PMID 12883420 DOI: 10.1097/00000542-200308000-00029  1
2003 Lynn AM, Nespeca MK, Bratton SL, Shen DD. Ventilatory effects of morphine infusions in cyanotic versus acyanotic infants after thoracotomy. Paediatric Anaesthesia. 13: 12-7. PMID 12535033 DOI: 10.1046/j.1460-9592.2003.00959.x  1
2002 Yang Z, Li CS, Shen DD, Ho RJ. Cloning and characterization of the rat multidrug resistance-associated protein 1. Aaps Pharmsci. 4: E15. PMID 12423064 DOI: 10.1208/ps040315  1
2002 Desjardins P, Black P, Papageorge M, Norwood T, Shen DD, Norris L, Ardia A. Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen. European Journal of Clinical Pharmacology. 58: 387-94. PMID 12242597 DOI: 10.1007/s00228-002-0491-0  1
2002 Yang Z, Woodahl EL, Wang XY, Bui T, Shen DD, Ho RJY. Semi-quantitative RT-PCR method to estimate full-length mRNA levels of the multidrug resistance gene Biotechniques. 33: 196-203. PMID 12139246  1
2002 Munster T, Gibbs JP, Shen D, Baethge BA, Botstein GR, Caldwell J, Dietz F, Ettlinger R, Golden HE, Lindsley H, McLaughlin GE, Moreland LW, Roberts WN, Rooney TW, Rothschild B, et al. Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis. Arthritis and Rheumatism. 46: 1460-9. PMID 12115175 DOI: 10.1002/art.10307  1
2002 Sachdeo RC, Sachdeo SK, Levy RH, Streeter AJ, Bishop FE, Kunze KL, Mather GG, Roskos LK, Shen DD, Thummel KE, Trager WF, Curtin CR, Doose DR, Gisclon LG, Bialer M. Topiramate and phenytoin pharmacokinetics during repetitive monotherapy and combination therapy to epileptic patients. Epilepsia. 43: 691-6. PMID 12102670 DOI: 10.1046/j.1528-1157.2002.41701.x  1
2002 Storek J, Lalovic BB, Rupert K, Dawson MA, Shen DD, Maloney DG. Kinetics of B, CD4 T, and CD8 T cells infused into humans: estimates of intravascular:extravascular ratios and total body counts. Clinical Immunology (Orlando, Fla.). 102: 249-57. PMID 11890711 DOI: 10.1006/clim.2001.5174  1
2001 Lin YS, Lockwood GF, Graham MA, Brian WR, Loi CM, Dobrinska MR, Shen DD, Watkins PB, Wilkinson GR, Kharasch ED, Thummel KE. In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration. Pharmacogenetics. 11: 781-91. PMID 11740342 DOI: 10.1097/00008571-200112000-00006  1
2001 Bethune CR, Bernards CM, Bui-Nguyen T, Shen DD, Ho RJY. The role of drug-lipid interactions on the disposition of liposome-formulated opioid analgesics in vitro and in vivo Anesthesia and Analgesia. 93: 928-933. PMID 11574359  1
2000 Wrighton SA, Schuetz EG, Thummel KE, Shen DD, Korzekwa KR, Watkins PB. The human CYP3A subfamily: Practical considerations Drug Metabolism Reviews. 32: 339-361. PMID 11139133 DOI: 10.1081/DMR-100102338  1
2000 Paine MF, Davis CL, Shen DD, Marsh CL, Raisys VA, Thummel KE. Can oral midazolam predict oral cyclosporine disposition? European Journal of Pharmaceutical Sciences. 12: 51-62. PMID 11121733 DOI: 10.1016/S0928-0987(00)00139-1  1
2000 Lynn AM, Nespeca MK, Bratton SL, Shen DD. Intravenous morphine in postoperative infants: intermittent bolus dosing versus targeted continuous infusions. Pain. 88: 89-95. PMID 11098103 DOI: 10.1016/S0304-3959(00)00313-4  1
2000 Scism JL, Powers KM, Artru AA, Lewis L, Shen DD. Probenecid-inhibitable efflux transport of valproic acid in the brain parenchymal cells of rabbits: A microdialysis study Brain Research. 884: 77-86. PMID 11082489 DOI: 10.1016/S0006-8993(00)02893-6  1
2000 Erjavec MK, Coda BA, Quynh N, Donaldson G, Risler L, Shen DD. Morphine-fluoxetine interactions in healthy volunteers: Analgesia and side effects Journal of Clinical Pharmacology. 40: 1286-1295. PMID 11075315  1
2000 Nishiyama T, Ho RJ, Shen DD, Yaksh TL. The effects of intrathecal morphine encapsulated in L- and D-dipalmitoylphosphatidyl choline liposomes on acute nociception in rats. Anesthesia and Analgesia. 91: 423-8. PMID 10910861  1
2000 Madani S, Howald WN, Lawrence RF, Shen DD. Analysis of hydroxylated and N-dealkylated metabolites of terfenadine in microsomal incubates by liquid chromatography-mass spectrometry Journal of Chromatography B: Biomedical Sciences and Applications. 741: 145-153. PMID 10872584 DOI: 10.1016/S0378-4347(00)00042-6  1
2000 Bauer LA, Horn JR, Maxon MS, Easterling TR, Shen DD, Strandness DE. Effect of metoprolol and verapamil administered separately and concurrently after single doses on liver blood flow and drug disposition. Journal of Clinical Pharmacology. 40: 533-43. PMID 10806607  1
2000 Gibbs MA, Baillie MT, Shen DD, Kunze KL, Thummel KE. Persistent inhibition of CYP3A4 by ketoconazole in modified Caco-2 cells. Pharmaceutical Research. 17: 299-305. PMID 10801218 DOI: 10.1023/A:1007550717526  1
2000 Scarlett LA, Madani S, Shen DD, Ho RJY. Development and characterization of a rapid and comprehensive genotyping assay to detect the most common variants in cytochrome P450 2D6 Pharmaceutical Research. 17: 242-246. PMID 10751042 DOI: 10.1023/A:1007585801905  1
2000 Ummenhofer WC, Arends RH, Shen DD, Bernards CM. Comparative spinal distribution and clearance kinetics of intrathecally administered morphine, fentanyl, alfentanil, and sufentanil Anesthesiology. 92: 739-753. PMID 10719953  1
2000 Koszdin KL, Shen DD, Bernards CM. Spinal cord bioavailability of methylprednisolone after intravenous and intrathecal administration: The role of P-glycoprotein Anesthesiology. 92: 156-163. PMID 10638912  1
1999 Madani S, Paine MF, Lewis L, Thummel KE, Shen DD. Comparison of CYP2D6 content and metoprolol oxidation between microsomes isolated from human livers and small intestines Pharmaceutical Research. 16: 1199-1205. PMID 10468020 DOI: 10.1023/A:1018989211864  1
1999 Pavlin DJ, Arends RH, Gunn HC, Van Norman G, Koerschgen ME, Shen DD. Optimal propofol-alfentanil combinations for supplementing nitrous oxide for outpatient surgery Anesthesiology. 91: 97-108. PMID 10422934 DOI: 10.1097/00000542-199907000-00017  1
1999 Fisher JM, Wrighton SA, Calamia JC, Shen DD, Kunze KL, Thummel KE. Midazolam metabolism by modified Caco-2 monolayers: effects of extracellular protein binding. The Journal of Pharmacology and Experimental Therapeutics. 289: 1143-50. PMID 10215698  1
1999 Fisher JM, Wrighton SA, Watkins PB, Schmiedlin-Ren P, Calamia JC, Shen DD, Kunze KL, Thummel KE. First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers. The Journal of Pharmacology and Experimental Therapeutics. 289: 1134-42. PMID 10215697  1
1999 Pierce CH, Lewandowski TA, Dills RL, Morgan MS, Wessels MA, Shen DD, Kalman DA. A comparison of 1H8- and 2H8-toluene toxicokinetics in men Xenobiotica. 29: 93-108. PMID 10078842 DOI: 10.1080/004982599238830  1
1999 Gibbs MA, Thummel KE, Shen DD, Kunze KL. Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: Comparison of K1 values and impact of CYP3A5 expression Drug Metabolism and Disposition. 27: 180-187. PMID 9929500  1
1999 Coda BA, Brown MC, Risler L, Syrjala K, Shen DD. Equivalent analgesia and side effects during epidural and pharmacokinetically tailored intravenous infusion with matching plasma alfentanil concentration Anesthesiology. 90: 98-108. PMID 9915318  1
1998 Arends RH, Hayashi TG, Luger TJ, Shen DD. Cotreatment with racemic fenfluramine inhibits the development of tolerance to morphine analgesia in rats Journal of Pharmacology and Experimental Therapeutics. 286: 585-592. PMID 9694907  1
1998 Lynn A, Nespeca MK, Bratton SL, Strauss SG, Shen DD. Clearance of morphine in postoperative infants during intravenous infusion: the influence of age and surgery. Anesthesia and Analgesia. 86: 958-63. PMID 9585276 DOI: 10.1097/00000539-199805000-00008  1
1997 Paine MF, Khalighi M, Fisher JM, Shen DD, Kunze KL, Marsh CL, Perkins JD, Thummel KE. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. The Journal of Pharmacology and Experimental Therapeutics. 283: 1552-62. PMID 9400033  1
1997 Scism JL, Powers KM, Artru AA, Chambers AC, Lewis L, Adkison KK, Kalhorn TF, Shen DD. Effects of probenecid on brain-cerebrospinal fluid-blood distribution kinetics of E-δ2-valproic acid in rabbits Drug Metabolism and Disposition. 25: 1337-1346. PMID 9394022  1
1997 Coda BA, O'Sullivan B, Donaldson G, Bohl S, Chapman CR, Shen DD. Comparative efficacy of patient-controlled administration of morphine, hydromorphone, or sufentanil for the treatment of oral mucositis pain following bone marrow transplantation Pain. 72: 333-346. PMID 9313274 DOI: 10.1016/S0304-3959(97)00059-6  1
1997 Dills RL, Shen DD. Methods to reduce background interferences in electron-capture gas chromatographic analysis of valproic acid and its unsaturated metabolites after derivatization with pentafluorobenzyl bromide Journal of Chromatography B: Biomedical Applications. 690: 139-152. PMID 9106038 DOI: 10.1016/S0378-4347(96)00405-7  1
1997 Thummel KE, Kunze KL, Shen DD. Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction Advanced Drug Delivery Reviews. 27: 99-127. DOI: 10.1016/S0169-409X(97)00039-2  1
1997 Martin SW, Furst DE, Klapperich R, Shen DD. Kinetics of hydroxychloroquine (HCQ) during high dose therapy in rheumatoid arthritis (RA) Clinical Pharmacology and Therapeutics. 61: 160.  1
1997 Pierce CH, Dills RL, Lewandowski TA, Morgan MS, Wessels MA, Shen DD, Kalman DA. Estimation of background exposure to toluene using a physiologically- based kinetic model Journal of Occupational Health. 39: 130-137.  1
1996 Bajpai M, Roskos LK, Shen DD, Levy RH. Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite Drug Metabolism and Disposition. 24: 1401-1403. PMID 8971149  1
1996 Adkison KDK, Powers KM, Artru AA, Shen DD. Effect of para-aminohippurate on the efflux of valproic acid from the central nervous system of the rabbit Epilepsy Research. 23: 95-104. PMID 8964279 DOI: 10.1016/0920-1211(95)00092-5  1
1996 Naora K, Ichikawa N, Nishimura N, Hirano H, Shen DD, Iwamoto K. Saturable transport of valproic acid in rat choroid plexus in vitro Journal of Pharmaceutical Sciences. 85: 423-426. PMID 8901082 DOI: 10.1021/js950436q  1
1996 Adkison KDK, Shen DD. Uptake of valproic acid into rat brain is mediated by a medium-chain fatty acid transporter Journal of Pharmacology and Experimental Therapeutics. 276: 1189-1200. PMID 8786552  1
1996 Paine MF, Shen DD, Kunze KL, Perkins JD, Marsh CL, McVicar JP, Barr DM, Gillies BS, Thummel KE. First-pass metabolism of midazolam by the human intestine Clinical Pharmacology and Therapeutics. 60: 14-24. PMID 8689807  1
1996 Pierce CH, Dills RL, Morgan MS, Nothstein GL, Shen DD, Kalman DA. Interindividual differences in 2H8-toluene toxicokinetics assessed by a semiempirical physiologically based model Toxicology and Applied Pharmacology. 139: 49-61. PMID 8685908 DOI: 10.1006/taap.1996.0142  1
1996 Thummel KE, O'Shea D, Paine MF, Shen DD, Kunze KL, Perkins JD, Wilkinson GR. Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism Clinical Pharmacology and Therapeutics. 59: 491-502. PMID 8646820 DOI: 10.1016/S0009-9236(96)90177-0  1
1996 Pavlin DJ, Coda B, Shen DD, Tschanz J, Nguyen Q, Schaffer R, Donaldson G, Jacobson RC, Chapman CR. Effects of combining propofol and alfentanil on ventilation, analgesia, sedation, and emesis in human volunteers Anesthesiology. 84: 23-37. PMID 8572340 DOI: 10.1097/00000542-199601000-00004  1
1995 Mautz DS, Shen DD, Nelson WL. Regioselectivity and Enantioselectivity of Metoprolol Oxidation by Two Variants of cDNA-Expressed P4502D6 Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 2053-2056. PMID 8786988 DOI: 10.1023/A:1016233115443  1
1995 Isackson J, Wallace MS, Ho RJ, Shen DD, Yaksh TL. Antinociception and side effects of L- and D-dipalmitoylphosphatidyl choline liposome-encapsulated alfentanil after spinal delivery in rats. Pharmacology & Toxicology. 77: 333-40. PMID 8778746  1
1995 Naora K, Shen DD. Mechanism of valproic acid uptake by isolated rat brain microvessels Epilepsy Research. 22: 97-106. PMID 8777904 DOI: 10.1016/0920-1211(95)00034-8  1
1995 Coda BA, Brown MC, Schaffer RL, Donaldson G, Shen DD. A pharmacokinetic approach to resolving spinal and systemic contributions to epidural alfentanil analgesia and side-effects Pain. 62: 329-337. PMID 8657433 DOI: 10.1016/0304-3959(95)00008-G  1
1995 Lown KS, Thummel KE, Benedict PE, Shen DD, Turgeon DK, Berent S, Watkins PB. The erythromycin breath test predicts the clearance of midazolam. Clinical Pharmacology and Therapeutics. 57: 16-24. PMID 7828377 DOI: 10.1016/0009-9236(95)90261-9  1
1995 Adkison KD, Ojemann GA, Rapport RL, Dills RL, Shen DD. Distribution of unsaturated metabolites of valproate in human and rat brain--pharmacologic relevance? Epilepsia. 36: 772-82. PMID 7635096 DOI: 10.1111/j.1528-1157.1995.tb01614.x  1
1995 Mautz DS, Nelson WL, Shen DD. Regioselective and stereoselective oxidation of metoprolol and bufuralol catalyzed by microsomes containing cDNA-expressed human P4502D6 Drug Metabolism and Disposition. 23: 513-517. PMID 7600921  1
1995 Agura ED, Cleveland Brown M, Schaffer R, Donaldson G, Shen DD. Antiemetic efficacy and pharmacokinetics of intravenous ondansetron infusion during chemotherapy conditioning for bone marrow transplant Bone Marrow Transplantation. 16: 213-222. PMID 7581139  1
1994 Vahter M, Mottet NK, Friberg L, Lind B, Shen DD, Burbacher T. Speciation of Mercury in the Primate Blood and Brain Following Long-Term Exposure to Methyl Mercury Toxicology and Applied Pharmacology. 124: 221-229. PMID 8122267 DOI: 10.1006/taap.1994.1026  1
1994 Adkison KDK, Artru AA, Powers KM, Shen DD. Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system Journal of Pharmacology and Experimental Therapeutics. 268: 797-805. PMID 8113992  1
1994 Marathe PH, Shen DD, Nelson WL. Metabolic kinetics of pseudoracemic propranolol in human liver microsomes: Enantioselectivity and quinidine inhibition Drug Metabolism and Disposition. 22: 237-247. PMID 8013280  1
1994 Coda BA, Brown MC, Schaffer R, Donaldson G, Jacobson R, Hautman B, Shen DD. Pharmacology of epidural fentanyl, alfentanil, and sufentanil in volunteers Anesthesiology. 81: 1149-1161. PMID 7978473  1
1994 Thummel KE, Shen DD, Podoll TD, Kunze KL, Trager WF, Bacchi CE, Marsh CL, McVicar JP, Barr DM, Perkins JD, Carithers RL. Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation Journal of Pharmacology and Experimental Therapeutics. 271: 557-566. PMID 7965756  1
1994 Thummel KE, Shen DD, Podoll TD, Kunze KL, Trager WF, Hartwell PS, Raisys VA, Marsh CL, McVicar JP, Barr DM, Perkins JD, Carithers RL. Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients Journal of Pharmacology and Experimental Therapeutics. 271: 549-556. PMID 7965755  1
1994 Arends RHGP, Zhang K, Levy R, Baillie TA, Shen DD. Stereoselective pharmacokinetics of stiripentol: an explanation for the development of tolerance to anticonvulsant effect Epilepsy Research. 18: 91-96. PMID 7957040 DOI: 10.1016/0920-1211(94)90001-9  1
1994 Wallace MS, Yanez AM, Ho RJY, Shen DD, Yaksh TL. Antinociception and side effects of liposome-encapsulated alfentanil after spinal delivery in rats Anesthesia and Analgesia. 79: 778-786. PMID 7943792  1
1994 Artru AA, Adkison KDK, Powers KM, Shen DD. Clearance of valproic acid from cerebrospinal fluid in anesthetized rabbit Journal of Neurosurgical Anesthesiology. 6: 193-200. PMID 7521700  1
1993 Bearman SI, Shen DD, Hinds MS, Hill HA, McDonald GB. A phase I/II study of prostaglandin E1 for the prevention of hepatic venocclusive disease after bone marrow transplantation. British Journal of Haematology. 84: 724-30. PMID 8217833  1
1993 Kim M, Shen DD, Eddy AC, Nelson WL. Inhibition of the enantioselective oxidative metabolism of metoprolol by verapamil in human liver microsomes Drug Metabolism and Disposition. 21: 309-317. PMID 8097702  1
1992 Shen DD, Ojemann GA, Rapport RL, Dills RL, Friel PN, Levy RH. Low and variable presence of valproic acid in human brain. Neurology. 42: 582-5. PMID 1549218 DOI: 10.1212/WNL.42.3.582  1
1992 Shen DD, Levy R, Savitch JL, Boddy AV, Tombret F, Lepage F. Comparative anticonvulsant potency and pharmacokinetics of (+)- and (-)-enantiomers of stiripentol Epilepsy Research. 12: 29-36. PMID 1526226 DOI: 10.1016/0920-1211(92)90088-B  1
1991 Semmes RLO, Shen DD. Comparative pharmacodynamics and brain distribution of E-Δ2-valproate and valproate in rats Epilepsia. 32: 232-241. PMID 2004628  1
1991 Marathe PH, Shen DD, Artru AA, Bowdle TA. Effect of serum protein binding on the entry of lidocaine into brain and cerebrospinal fluid in dogs Anesthesiology. 75: 804-812. PMID 1952206  1
1991 Murthy SS, Nelson WL, Shen DD, Power JM, Cahill CM, McLean AJ. Pharmacokinetic interaction between verapamil and metoprolol in the dog. Stereochemical aspects. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 19: 1093-100. PMID 1687016  1
1990 Shen DD, Levy R, Moor MJ, Savitch JL. Efficacy of stiripentol in the intravenous pentylenetetrazol infusion seizure model in the rat Epilepsy Research. 7: 40-48. PMID 2292245 DOI: 10.1016/0920-1211(90)90052-W  1
1990 Semmes RLO, Shen DD. Nonlinear Binding of Valproic Acid (VPA) and E-Δ2-Valproic Acid to Rat Plasma Proteins Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 7: 461-467. PMID 2114617 DOI: 10.1023/A:1015804413818  1
1990 Semmes RLO, Shen DD. A reversible clearance model for the enterohepatic circulation of drug and conjugate metabolite pair Drug Metabolism and Disposition. 18: 80-87. PMID 1970782  1
1989 Pollack GM, Shen DD, Dorr MB. Contribution of metabolites to the route- and time-dependent hepatic effects of di-(2-ethylhexyl)phthalate in the rat Journal of Pharmacology and Experimental Therapeutics. 248: 176-181. PMID 2913270  1
1989 Laganière S, Kwong E, Shen DD. Stereoselective high-performance liquid chromatographic assay for propranolol enantiomers in serum Journal of Chromatography B: Biomedical Sciences and Applications. 488: 407-416. PMID 2745631 DOI: 10.1016/S0378-4347(00)82964-3  1
1988 Kwong EC, Laganière S, Savitch JL, Nelson WL, Shen DD. Alteration in the disposition and metabolism of S(-)-propranolol in rats with active respiratory viral infection Life Sciences. 42: 1245-1252. PMID 3347149 DOI: 10.1016/0024-3205(88)90556-5  1
1988 Semmes RLO, Shen DD. Capillary gas chromatographic assay for valproic acid and its 2-desaturated metabolite in brain and plasma Journal of Chromatography B: Biomedical Sciences and Applications. 432: 185-197. PMID 3146579 DOI: 10.1016/S0378-4347(00)80644-1  1
1987 Laganiere S, Shen DD. Altered S(-)-propranolol disposition in bilateral ureter-ligated rats Nephron. 46: 305-311. PMID 3627324  1
1987 Kwong EC, Shen DD. Versatile isocratic high-performance liquid chromatographic assay for propranolol and its basic, neutral and acidic metabolites in biological fluids Journal of Chromatography B: Biomedical Sciences and Applications. 414: 365-379. PMID 3571404 DOI: 10.1016/0378-4347(87)80061-0  1
1986 Pollack GM, McHugh WB, Gengo FM, Ermer JC, Shen DD. Accumulation and washout kinetics of valproic acid and its active metabolites Journal of Clinical Pharmacology. 26: 668-676. PMID 3098806  1
1986 Shen DD, Pollack GM. Reply Toxicology and Applied Pharmacology. 82: 384-385. DOI: 10.1016/0041-008X(86)90217-6  1
1985 Pollack GM, Buchanan JF, Slaughter RL, Kohli RK, Shen DD. Circulating concentrations of di(2-ethylhexyl) phthalate and its de-esterified phthalic acid products following plasticizer exposure in patients receiving hemodialysis. Toxicology and Applied Pharmacology. 79: 257-67. PMID 4002227 DOI: 10.1016/0041-008X(85)90347-3  1
1985 Pollack GM, Li RCK, Ermer JC, Shen DD. Effects of route of administration and repetitive dosing on the disposition kinetics of di(2-ethylhexyl) phthalate and its mono-de-esterified metabolite in rats Toxicology and Applied Pharmacology. 79: 246-256. PMID 4002226 DOI: 10.1016/0041-008X(85)90346-1  1
1985 Terao N, Shen DD. Reduced extraction of l-propranolol by perfused rat liver in the presence of uremic blood Journal of Pharmacology and Experimental Therapeutics. 233: 277-284. PMID 3999018  1
1985 Pollack GM, Shen DD. A timed intravenous pentylenetetrazol infusion scizure model for quantitating the anticonvulsant effect of valproic acid in the rat Journal of Pharmacological Methods. 13: 135-146. PMID 3920448 DOI: 10.1016/0160-5402(85)90057-9  1
1984 Pollack GM, Li RCK, Shen DD. Dose-dependent pharmacokinetics of antipyrine in the rat Research Communications in Chemical Pathology and Pharmacology. 44: 69-81. PMID 6729251  1
1984 Pollack GM, Shen DD. Effect of renal failure and Bis(2‐ethylhexyl) phthalate pretreatment on the disposition and metabolism of antipyrine in the rat Journal of Pharmaceutical Sciences. 73: 29-33. PMID 6694077 DOI: 10.1002/jps.2600730108  1
1984 Terao N, Shen DD. Pharmacokinetics of l-propranolol during repetitive dosing in normal and uranyl nitrate-induced renal failure rats Journal of Pharmacokinetics and Biopharmaceutics. 12: 479-493. PMID 6520744 DOI: 10.1007/BF01060127  1
1984 Pollack GM, Slaughter RL, Buchanan JF, Shen DD. High-performance liquid chromatographic procedure for the determination of di-(2-ethylhexyl)phthalate in human blood specimens. Problems of variable-extraction yield and the use of standard addition for calibration. Journal of Chromatography. 311: 101-8. PMID 6520150 DOI: 10.1016/S0378-4347(00)84695-2  1
1984 Shen DD, Pollack GM. A reply to 'Problems involved with developing a suitable model for evaluating exposure to bis(2-ethylhexyl) phthalate from medical devices Journal of Pharmaceutical Sciences. 73: 1334-1335. PMID 6491968  1
1984 Georgitis JW, Szefler SJ, Baswell B, Shen DD. Use of pharmacokinetic profile in evaluating patients with repeatedly low theophylline concentrations Annals of Allergy. 53: 231-235. PMID 6476482  1
1984 Pollack GM, Baswell B, Szefler SJ, Shen DD. Comparison of inter- and intra-subject variation in oral absorption of theophylline from sustained-release products International Journal of Pharmaceutics. 21: 3-16. DOI: 10.1016/0378-5173(84)90198-4  1
1980 Shen DD, Cunningham JL, Shudo I, Azarnoff DL. Disposition kinetics of disopyramide in patients with renal insufficiency Biopharmaceutics and Drug Disposition. 1: 133-140. PMID 7448340 DOI: 10.1002/bdd.2510010308  1
1980 Shen DD, Hosler JP, Schroder RL, Azarnoff DL. Pharmacokinetics of hydralazine and its acid-labile hydrazone metabolites in relation to acetylator phenotype Journal of Pharmacokinetics and Biopharmaceutics. 8: 53-68. PMID 7381691 DOI: 10.1007/BF01059448  1
1978 Cunningham JL, Shen DD, Shudo I, Azarnoff DL. The effect of non-linear disposition kinetics on the systemic availability of disopyramide British Journal of Clinical Pharmacology. 5: 343-346. DOI: 10.1111/j.1365-2125.1978.tb01719.x  1
1977 Cunningham JL, Shen DD, Shudo I, Azarnoff DL. The Effects of Urine pH and Plasma Protein Binding on the Renal Clearance of Disopyramide Clinical Pharmacokinetics. 2: 373-383. PMID 21054 DOI: 10.2165/00003088-197702050-00004  1
Show low-probability matches.