| Year |
Citation |
Score |
| 2022 |
Lalovic B, Shireman L, Shen DD, Cherrier M. Model-Based Analysis of the Influence of Alcohol Use and Age on Pharmacokinetics-Pharmacodynamics of Oral Oxycodone in Middle-Age and Older Community Dwelling Adults. Journal of Clinical Pharmacology. PMID 35394079 DOI: 10.1002/jcph.2058 |
0.635 |
|
| 2020 |
McAdams RM, Pak D, Lalovic B, Phillips B, Shen DD. Dexmedetomidine Pharmacokinetics in Neonates with Hypoxic-Ischemic Encephalopathy Receiving Hypothermia. Anesthesiology Research and Practice. 2020: 2582965. PMID 32158472 DOI: 10.1155/2020/2582965 |
0.676 |
|
| 2006 |
Lalovic B, Kharasch E, Hoffer C, Risler L, Liu-Chen LY, Shen DD. Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites. Clinical Pharmacology and Therapeutics. 79: 461-79. PMID 16678548 DOI: 10.1016/J.Clpt.2006.01.009 |
0.685 |
|
| 2004 |
Lalovic B, Phillips B, Risler LL, Howald W, Shen DD. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 447-54. PMID 15039299 DOI: 10.1124/Dmd.32.4.447 |
0.664 |
|
| 2004 |
Burbacher TM, Shen DD, Lalovic B, Grant KS, Sheppard L, Damian D, Ellis S, Liberato N. Chronic maternal methanol inhalation in nonhuman primates (Macaca fascicularis): exposure and toxicokinetics prior to and during pregnancy. Neurotoxicology and Teratology. 26: 201-21. PMID 15019954 DOI: 10.1016/J.Ntt.2003.10.003 |
0.665 |
|
| 2002 |
Storek J, Lalovic BB, Rupert K, Dawson MA, Shen DD, Maloney DG. Kinetics of B, CD4 T, and CD8 T cells infused into humans: estimates of intravascular:extravascular ratios and total body counts. Clinical Immunology (Orlando, Fla.). 102: 249-57. PMID 11890711 DOI: 10.1006/clim.2001.5174 |
0.628 |
|
| 1989 |
Pollack GM, Shen DD, Dorr MB. Contribution of metabolites to the route- and time-dependent hepatic effects of di-(2-ethylhexyl)phthalate in the rat Journal of Pharmacology and Experimental Therapeutics. 248: 176-181. PMID 2913270 |
0.554 |
|
| 1986 |
Pollack GM, McHugh WB, Gengo FM, Ermer JC, Shen DD. Accumulation and washout kinetics of valproic acid and its active metabolites Journal of Clinical Pharmacology. 26: 668-676. PMID 3098806 DOI: 10.1002/J.1552-4604.1986.Tb02970.X |
0.61 |
|
| 1986 |
Shen DD, Pollack GM. Reply Toxicology and Applied Pharmacology. 82: 384-385. DOI: 10.1016/0041-008X(86)90217-6 |
0.441 |
|
| 1985 |
Pollack GM, Buchanan JF, Slaughter RL, Kohli RK, Shen DD. Circulating concentrations of di(2-ethylhexyl) phthalate and its de-esterified phthalic acid products following plasticizer exposure in patients receiving hemodialysis. Toxicology and Applied Pharmacology. 79: 257-67. PMID 4002227 DOI: 10.1016/0041-008X(85)90347-3 |
0.564 |
|
| 1985 |
Pollack GM, Li RCK, Ermer JC, Shen DD. Effects of route of administration and repetitive dosing on the disposition kinetics of di(2-ethylhexyl) phthalate and its mono-de-esterified metabolite in rats Toxicology and Applied Pharmacology. 79: 246-256. PMID 4002226 DOI: 10.1016/0041-008X(85)90346-1 |
0.627 |
|
| 1985 |
Pollack GM, Shen DD. A timed intravenous pentylenetetrazol infusion scizure model for quantitating the anticonvulsant effect of valproic acid in the rat Journal of Pharmacological Methods. 13: 135-146. PMID 3920448 DOI: 10.1016/0160-5402(85)90057-9 |
0.586 |
|
| 1984 |
Pollack GM, Li RCK, Shen DD. Dose-dependent pharmacokinetics of antipyrine in the rat Research Communications in Chemical Pathology and Pharmacology. 44: 69-81. PMID 6729251 |
0.567 |
|
| 1984 |
Pollack GM, Shen DD. Effect of renal failure and Bis(2‐ethylhexyl) phthalate pretreatment on the disposition and metabolism of antipyrine in the rat Journal of Pharmaceutical Sciences. 73: 29-33. PMID 6694077 DOI: 10.1002/Jps.2600730108 |
0.58 |
|
| 1984 |
Terao N, Shen DD. Pharmacokinetics of l-propranolol during repetitive dosing in normal and uranyl nitrate-induced renal failure rats Journal of Pharmacokinetics and Biopharmaceutics. 12: 479-493. PMID 6520744 DOI: 10.1007/Bf01060127 |
0.381 |
|
| 1984 |
Pollack GM, Slaughter RL, Buchanan JF, Shen DD. High-performance liquid chromatographic procedure for the determination of di-(2-ethylhexyl)phthalate in human blood specimens. Problems of variable-extraction yield and the use of standard addition for calibration. Journal of Chromatography. 311: 101-8. PMID 6520150 DOI: 10.1016/S0378-4347(00)84695-2 |
0.549 |
|
| 1984 |
Shen DD, Pollack GM. A reply to 'Problems involved with developing a suitable model for evaluating exposure to bis(2-ethylhexyl) phthalate from medical devices Journal of Pharmaceutical Sciences. 73: 1334-1335. PMID 6491968 DOI: 10.1002/Jps.2600730945 |
0.465 |
|
| 1984 |
Pollack GM, Baswell B, Szefler SJ, Shen DD. Comparison of inter- and intra-subject variation in oral absorption of theophylline from sustained-release products International Journal of Pharmaceutics. 21: 3-16. DOI: 10.1016/0378-5173(84)90198-4 |
0.538 |
|
| 1980 |
Shen DD, Hosler JP, Schroder RL, Azarnoff DL. Pharmacokinetics of hydralazine and its acid-labile hydrazone metabolites in relation to acetylator phenotype Journal of Pharmacokinetics and Biopharmaceutics. 8: 53-68. PMID 7381691 DOI: 10.1007/BF01059448 |
0.303 |
|
| 1976 |
Chremos AN, Shen D, Gibaldi M, Proctor JD, Newman JH. Time-dependent change in renal clearance of bethanidine in humans. Journal of Pharmaceutical Sciences. 65: 140-2. PMID 1255421 DOI: 10.1002/Jps.2600650136 |
0.381 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1990 |
Shen DD, Levy R, Moor MJ, Savitch JL. Efficacy of stiripentol in the intravenous pentylenetetrazol infusion seizure model in the rat Epilepsy Research. 7: 40-48. PMID 2292245 DOI: 10.1016/0920-1211(90)90052-W |
0.296 |
|
| 1984 |
Georgitis JW, Szefler SJ, Baswell B, Shen DD. Use of pharmacokinetic profile in evaluating patients with repeatedly low theophylline concentrations Annals of Allergy. 53: 231-235. PMID 6476482 |
0.279 |
|
| 2001 |
Lin YS, Lockwood GF, Graham MA, Brian WR, Loi CM, Dobrinska MR, Shen DD, Watkins PB, Wilkinson GR, Kharasch ED, Thummel KE. In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration. Pharmacogenetics. 11: 781-91. PMID 11740342 DOI: 10.1097/00008571-200112000-00006 |
0.266 |
|
| 2004 |
Bowdle TA, Even A, Shen DD, Swardstrom M. Methadone for the induction of anesthesia: plasma histamine concentration, arterial blood pressure, and heart rate. Anesthesia and Analgesia. 98: 1692-7, table of con. PMID 15155330 |
0.262 |
|
| 1981 |
Fixley M, Shen DD, Azarnoff DL. Theophylline bioavailability: a comparison of the oral absorption of a theophylline elixir and two combination theophylline tablets to intravenous aminophylline. The American Review of Respiratory Disease. 115: 955-62. PMID 262107 DOI: 10.1164/arrd.1977.115.6.955 |
0.26 |
|
| 1996 |
Paine MF, Shen DD, Kunze KL, Perkins JD, Marsh CL, McVicar JP, Barr DM, Gillies BS, Thummel KE. First-pass metabolism of midazolam by the human intestine Clinical Pharmacology and Therapeutics. 60: 14-24. PMID 8689807 DOI: 10.1016/S0009-9236(96)90162-9 |
0.257 |
|
| 2021 |
Shum S, Shen DD, Isoherranen N. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34407992 DOI: 10.1124/dmd.121.000612 |
0.256 |
|
| 2018 |
Ryu RJ, Easterling TR, Caritis SN, Venkataramanan R, Umans JG, Ahmed MS, Clark S, Kantrowitz-Gordon I, Hays K, Bennett B, Honaker MT, Thummel KE, Shen DD, Hebert MF. Prednisone Pharmacokinetics During Pregnancy and Lactation. Journal of Clinical Pharmacology. PMID 29733485 DOI: 10.1002/Jcph.1122 |
0.253 |
|
| 1991 |
Murthy SS, Nelson WL, Shen DD, Power JM, Cahill CM, McLean AJ. Pharmacokinetic interaction between verapamil and metoprolol in the dog. Stereochemical aspects. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 19: 1093-100. PMID 1687016 |
0.253 |
|
| 1977 |
Cunningham JL, Shen DD, Shudo I, Azarnoff DL. The Effects of Urine pH and Plasma Protein Binding on the Renal Clearance of Disopyramide Clinical Pharmacokinetics. 2: 373-383. PMID 21054 DOI: 10.2165/00003088-197702050-00004 |
0.249 |
|
| 1978 |
Shen DD, Fixley M, Azarnoff DL. Theophylline bioavailability following chronic dosing of an elixir and two solid dosage forms. Journal of Pharmaceutical Sciences. 67: 916-9. PMID 660507 DOI: 10.1002/jps.2600670711 |
0.248 |
|
| 2006 |
Dai Y, Hebert MF, Isoherranen N, Davis CL, Marsh C, Shen DD, Thummel KE. Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 836-47. PMID 16501005 DOI: 10.1124/Dmd.105.008680 |
0.246 |
|
| 2020 |
Chen KF, Chan LN, Senn TD, Oelschlager BK, Flum DR, Shen DD, Horn JR, Lin YS. The Impact of Proximal Roux-en-Y Gastric Bypass Surgery on Acetaminophen Absorption and Metabolism. Pharmacotherapy. PMID 31960977 DOI: 10.1002/Phar.2368 |
0.245 |
|
| 2010 |
Eyal S, Easterling TR, Carr D, Umans JG, Miodovnik M, Hankins GD, Clark SM, Risler L, Wang J, Kelly EJ, Shen DD, Hebert MF. Pharmacokinetics of metformin during pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 833-40. PMID 20118196 DOI: 10.1124/Dmd.109.031245 |
0.244 |
|
| 1996 |
Thummel KE, O'Shea D, Paine MF, Shen DD, Kunze KL, Perkins JD, Wilkinson GR. Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism Clinical Pharmacology and Therapeutics. 59: 491-502. PMID 8646820 DOI: 10.1016/S0009-9236(96)90177-0 |
0.241 |
|
| 1987 |
Laganiere S, Shen DD. Altered S(-)-propranolol disposition in bilateral ureter-ligated rats Nephron. 46: 305-311. PMID 3627324 |
0.241 |
|
| 1983 |
Day RO, Shen DD, Azarnoff DL. Induction of salicyluric acid formation in rheumatoid arthritis patients treated with salicylates. Clinical Pharmacokinetics. 8: 263-71. PMID 6851371 DOI: 10.2165/00003088-198308030-00005 |
0.24 |
|
| 1999 |
Fisher JM, Wrighton SA, Calamia JC, Shen DD, Kunze KL, Thummel KE. Midazolam metabolism by modified Caco-2 monolayers: effects of extracellular protein binding. The Journal of Pharmacology and Experimental Therapeutics. 289: 1143-50. PMID 10215698 |
0.24 |
|
| 1999 |
Fisher JM, Wrighton SA, Watkins PB, Schmiedlin-Ren P, Calamia JC, Shen DD, Kunze KL, Thummel KE. First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers. The Journal of Pharmacology and Experimental Therapeutics. 289: 1134-42. PMID 10215697 |
0.238 |
|
| 1994 |
Coda BA, Brown MC, Schaffer R, Donaldson G, Jacobson R, Hautman B, Shen DD. Pharmacology of epidural fentanyl, alfentanil, and sufentanil in volunteers Anesthesiology. 81: 1149-1161. PMID 7978473 |
0.237 |
|
| 1995 |
Coda BA, Brown MC, Schaffer RL, Donaldson G, Shen DD. A pharmacokinetic approach to resolving spinal and systemic contributions to epidural alfentanil analgesia and side-effects Pain. 62: 329-337. PMID 8657433 DOI: 10.1016/0304-3959(95)00008-G |
0.236 |
|
| 1981 |
Pitterman AB, Rollins DE, Shen DD, Hurwitz A, Hassanein KM. Alpha adrenoceptor blockade with oral prazosin. Clinical Pharmacology and Therapeutics. 29: 143-8. PMID 6109587 DOI: 10.1038/clpt.1981.23 |
0.235 |
|
| 1999 |
Coda BA, Brown MC, Risler L, Syrjala K, Shen DD. Equivalent analgesia and side effects during epidural and pharmacokinetically tailored intravenous infusion with matching plasma alfentanil concentration Anesthesiology. 90: 98-108. PMID 9915318 |
0.233 |
|
| 1996 |
Pierce CH, Dills RL, Morgan MS, Nothstein GL, Shen DD, Kalman DA. Interindividual differences in 2H8-toluene toxicokinetics assessed by a semiempirical physiologically based model Toxicology and Applied Pharmacology. 139: 49-61. PMID 8685908 DOI: 10.1006/taap.1996.0142 |
0.231 |
|
| 2012 |
Zheng S, Tasnif Y, Hebert MF, Davis CL, Shitara Y, Calamia JC, Lin YS, Shen DD, Thummel KE. Measurement and compartmental modeling of the effect of CYP3A5 gene variation on systemic and intrarenal tacrolimus disposition. Clinical Pharmacology and Therapeutics. 92: 737-45. PMID 23073208 DOI: 10.1038/Clpt.2012.175 |
0.23 |
|
| 1978 |
Cunningham JL, Shen DD, Azarnoff DL. Pharmacokinetics of Disopyramid Rinsho Yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 9: 14-16. DOI: 10.3999/jscpt.9.14 |
0.229 |
|
| 1992 |
Shen DD, Levy R, Savitch JL, Boddy AV, Tombret F, Lepage F. Comparative anticonvulsant potency and pharmacokinetics of (+)- and (-)-enantiomers of stiripentol Epilepsy Research. 12: 29-36. PMID 1526226 DOI: 10.1016/0920-1211(92)90088-B |
0.226 |
|
| 1997 |
Paine MF, Khalighi M, Fisher JM, Shen DD, Kunze KL, Marsh CL, Perkins JD, Thummel KE. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. The Journal of Pharmacology and Experimental Therapeutics. 283: 1552-62. PMID 9400033 |
0.226 |
|
| 2006 |
Johns DO, Daniell WE, Shen DD, Kalman DA, Dills RL, Morgan MS. Ethanol-induced increase in the metabolic clearance of 1,1,1-trichloroethane in human volunteers. Toxicological Sciences : An Official Journal of the Society of Toxicology. 92: 61-70. PMID 16638923 DOI: 10.1093/toxsci/kfj210 |
0.225 |
|
| 1994 |
Wallace MS, Yanez AM, Ho RJY, Shen DD, Yaksh TL. Antinociception and side effects of liposome-encapsulated alfentanil after spinal delivery in rats Anesthesia and Analgesia. 79: 778-786. PMID 7943792 |
0.224 |
|
| 1991 |
Marathe PH, Shen DD, Artru AA, Bowdle TA. Effect of serum protein binding on the entry of lidocaine into brain and cerebrospinal fluid in dogs Anesthesiology. 75: 804-812. PMID 1952206 |
0.223 |
|
| 2000 |
Madani S, Howald WN, Lawrence RF, Shen DD. Analysis of hydroxylated and N-dealkylated metabolites of terfenadine in microsomal incubates by liquid chromatography-mass spectrometry Journal of Chromatography B: Biomedical Sciences and Applications. 741: 145-153. PMID 10872584 DOI: 10.1016/S0378-4347(00)00042-6 |
0.223 |
|
| 1985 |
Terao N, Shen DD. Reduced extraction of l-propranolol by perfused rat liver in the presence of uremic blood Journal of Pharmacology and Experimental Therapeutics. 233: 277-284. PMID 3999018 |
0.222 |
|
| 1994 |
Arends RHGP, Zhang K, Levy R, Baillie TA, Shen DD. Stereoselective pharmacokinetics of stiripentol: an explanation for the development of tolerance to anticonvulsant effect Epilepsy Research. 18: 91-96. PMID 7957040 DOI: 10.1016/0920-1211(94)90001-9 |
0.222 |
|
| 1995 |
Lown KS, Thummel KE, Benedict PE, Shen DD, Turgeon DK, Berent S, Watkins PB. The erythromycin breath test predicts the clearance of midazolam. Clinical Pharmacology and Therapeutics. 57: 16-24. PMID 7828377 DOI: 10.1016/0009-9236(95)90261-9 |
0.221 |
|
| 2009 |
Buchanan ML, Easterling TR, Carr DB, Shen DD, Risler LJ, Nelson WL, Mattison DR, Hebert MF. Clonidine pharmacokinetics in pregnancy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 702-5. PMID 19116263 DOI: 10.1124/Dmd.108.024984 |
0.219 |
|
| 2014 |
Shen DD, Liu J, Huang H, Zhang T, Zhang YL. Pharmacokinetics in rabbits of oxybutynin hydrochloride ethosomal gel Chinese Pharmaceutical Journal. 49: 588-591. DOI: 10.11669/cpj.2014.07.019 |
0.218 |
|
| 1999 |
Pavlin DJ, Arends RH, Gunn HC, Van Norman G, Koerschgen ME, Shen DD. Optimal propofol-alfentanil combinations for supplementing nitrous oxide for outpatient surgery Anesthesiology. 91: 97-108. PMID 10422934 DOI: 10.1097/00000542-199907000-00017 |
0.217 |
|
| 1997 |
Thummel KE, Kunze KL, Shen DD. Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction Advanced Drug Delivery Reviews. 27: 99-127. DOI: 10.1016/S0169-409X(97)00039-2 |
0.215 |
|
| 1981 |
Mintun M, Himmelstein KJ, Schroder RL, Gibaldi M, Shen DD. Tissue distribution kinetics of tetraethylammonium ion in the rat. Journal of Pharmacokinetics and Biopharmaceutics. 8: 373-409. PMID 7431228 DOI: 10.1007/BF01059385 |
0.214 |
|
| 2006 |
Salinger DH, McCune JS, Ren AG, Shen DD, Slattery JT, Phillips B, McDonald GB, Vicini P. Real-time dose adjustment of cyclophosphamide in a preparative regimen for hematopoietic cell transplant: a Bayesian pharmacokinetic approach. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4888-98. PMID 16914577 DOI: 10.1158/1078-0432.Ccr-05-2079 |
0.213 |
|
| 2000 |
Bauer LA, Horn JR, Maxon MS, Easterling TR, Shen DD, Strandness DE. Effect of metoprolol and verapamil administered separately and concurrently after single doses on liver blood flow and drug disposition. Journal of Clinical Pharmacology. 40: 533-43. PMID 10806607 |
0.212 |
|
| 2018 |
Tian DD, Kellogg JJ, Okut N, Oberlies NH, Cech NB, Shen DD, McCune JS, Paine MF. Identification of Intestinal UDP-Glucuronosyltransferase Inhibitors in Green Tea () Using a Biochemometric Approach: Application to Raloxifene as a Test Drug via In Vitro to In Vivo Extrapolation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29467215 DOI: 10.1124/Dmd.117.079491 |
0.212 |
|
| 2013 |
Hebert MF, Zheng S, Hays K, Shen DD, Davis CL, Umans JG, Miodovnik M, Thummel KE, Easterling TR. Interpreting tacrolimus concentrations during pregnancy and postpartum. Transplantation. 95: 908-15. PMID 23274970 DOI: 10.1097/Tp.0B013E318278D367 |
0.21 |
|
| 1997 |
Martin SW, Furst DE, Klapperich R, Shen DD. Kinetics of hydroxychloroquine (HCQ) during high dose therapy in rheumatoid arthritis (RA) Clinical Pharmacology and Therapeutics. 61: 160. |
0.209 |
|
| 2010 |
Ho BE, Shen DD, McCune JS, Bui T, Risler L, Yang Z, Ho RJ. Effects of Garlic on Cytochromes P450 2C9- and 3A4-Mediated Drug Metabolism in Human Hepatocytes. Scientia Pharmaceutica. 78: 473-81. PMID 20936048 DOI: 10.3797/scipharm.1002-11 |
0.207 |
|
| 1990 |
Semmes RLO, Shen DD. A reversible clearance model for the enterohepatic circulation of drug and conjugate metabolite pair Drug Metabolism and Disposition. 18: 80-87. PMID 1970782 |
0.207 |
|
| 1988 |
Kwong EC, Laganière S, Savitch JL, Nelson WL, Shen DD. Alteration in the disposition and metabolism of S(-)-propranolol in rats with active respiratory viral infection Life Sciences. 42: 1245-1252. PMID 3347149 DOI: 10.1016/0024-3205(88)90556-5 |
0.206 |
|
| 1999 |
Madani S, Paine MF, Lewis L, Thummel KE, Shen DD. Comparison of CYP2D6 content and metoprolol oxidation between microsomes isolated from human livers and small intestines Pharmaceutical Research. 16: 1199-1205. PMID 10468020 DOI: 10.1023/A:1018989211864 |
0.203 |
|
| 1994 |
Marathe PH, Shen DD, Nelson WL. Metabolic kinetics of pseudoracemic propranolol in human liver microsomes: Enantioselectivity and quinidine inhibition Drug Metabolism and Disposition. 22: 237-247. PMID 8013280 |
0.203 |
|
| 2018 |
Cheng SL, Li X, Lehmler HJ, Phillips B, Shen D, Cui JY. Gut Microbiota Modulates Interactions Between Polychlorinated Biphenyls and Bile Acid Homeostasis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 166: 269-287. PMID 30496569 DOI: 10.1093/toxsci/kfy208 |
0.203 |
|
| 2019 |
Han LW, Ryu RJ, Cusumano M, Easterling TR, Phillips BR, Risler LJ, Shen DD, Hebert MF. Effect of N-Acetyltransferase 2 Genotype on the Pharmacokinetics of Hydralazine During Pregnancy. Journal of Clinical Pharmacology. PMID 31257615 DOI: 10.1002/jcph.1477 |
0.202 |
|
| 1980 |
Cathcart-Rake WF, Coker JE, Atkins FL, Huffman DH, Hassanein KM, Shen DD, Azarnoff DL. The effect of concurrent oral administration of propranolol and disopyramide on cardiac function in healthy men. Circulation. 61: 938-45. PMID 7363436 DOI: 10.1161/01.CIR.61.5.938 |
0.201 |
|
| 1994 |
Thummel KE, Shen DD, Podoll TD, Kunze KL, Trager WF, Hartwell PS, Raisys VA, Marsh CL, McVicar JP, Barr DM, Perkins JD, Carithers RL. Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients Journal of Pharmacology and Experimental Therapeutics. 271: 549-556. PMID 7965755 |
0.201 |
|
| 2023 |
Clarke JD, Judson SM, Tian DD, Kirby TO, Tanna RS, Matula-Péntek A, Horváth M, Layton ME, White JR, Cech NB, Thummel KE, McCune JS, Shen DD, Paine MF. Co-consuming green tea with raloxifene decreases raloxifene systemic exposure in healthy adult participants. Clinical and Translational Science. PMID 37639334 DOI: 10.1111/cts.13578 |
0.201 |
|
| 1997 |
Pierce CH, Dills RL, Lewandowski TA, Morgan MS, Wessels MA, Shen DD, Kalman DA. Estimation of background exposure to toluene using a physiologically- based kinetic model Journal of Occupational Health. 39: 130-137. DOI: 10.1539/Joh.39.130 |
0.2 |
|
| 2002 |
Munster T, Gibbs JP, Shen D, Baethge BA, Botstein GR, Caldwell J, Dietz F, Ettlinger R, Golden HE, Lindsley H, McLaughlin GE, Moreland LW, Roberts WN, Rooney TW, Rothschild B, et al. Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis. Arthritis and Rheumatism. 46: 1460-9. PMID 12115175 DOI: 10.1002/art.10307 |
0.199 |
|
| 2014 |
Shuster DL, Risler LJ, Prasad B, Calamia JC, Voellinger JL, Kelly EJ, Unadkat JD, Hebert MF, Shen DD, Thummel KE, Mao Q. Identification of CYP3A7 for glyburide metabolism in human fetal livers. Biochemical Pharmacology. 92: 690-700. PMID 25450675 DOI: 10.1016/J.Bcp.2014.09.025 |
0.199 |
|
| 2000 |
Paine MF, Davis CL, Shen DD, Marsh CL, Raisys VA, Thummel KE. Can oral midazolam predict oral cyclosporine disposition? European Journal of Pharmaceutical Sciences. 12: 51-62. PMID 11121733 DOI: 10.1016/S0928-0987(00)00139-1 |
0.199 |
|
| 1994 |
Thummel KE, Shen DD, Podoll TD, Kunze KL, Trager WF, Bacchi CE, Marsh CL, McVicar JP, Barr DM, Perkins JD, Carithers RL. Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation Journal of Pharmacology and Experimental Therapeutics. 271: 557-566. PMID 7965756 |
0.198 |
|
| 1991 |
Semmes RLO, Shen DD. Comparative pharmacodynamics and brain distribution of E-Δ2-valproate and valproate in rats Epilepsia. 32: 232-241. PMID 2004628 |
0.197 |
|
| 1993 |
Kim M, Shen DD, Eddy AC, Nelson WL. Inhibition of the enantioselective oxidative metabolism of metoprolol by verapamil in human liver microsomes Drug Metabolism and Disposition. 21: 309-317. PMID 8097702 |
0.197 |
|
| 1995 |
Adkison KD, Ojemann GA, Rapport RL, Dills RL, Shen DD. Distribution of unsaturated metabolites of valproate in human and rat brain--pharmacologic relevance? Epilepsia. 36: 772-82. PMID 7635096 DOI: 10.1111/j.1528-1157.1995.tb01614.x |
0.195 |
|
| 2009 |
Li M, Andrew MA, Wang J, Salinger DH, Vicini P, Grady RW, Phillips B, Shen DD, Anderson GD. Effects of cranberry juice on pharmacokinetics of beta-lactam antibiotics following oral administration. Antimicrobial Agents and Chemotherapy. 53: 2725-32. PMID 19398645 DOI: 10.1128/Aac.00774-08 |
0.195 |
|
| 2014 |
Shuster DL, Risler LJ, Liang CK, Rice KM, Shen DD, Hebert MF, Thummel KE, Mao Q. Maternal-fetal disposition of glyburide in pregnant mice is dependent on gestational age. The Journal of Pharmacology and Experimental Therapeutics. 350: 425-34. PMID 24898265 DOI: 10.1124/Jpet.114.213470 |
0.194 |
|
| 2003 |
Bernards CM, Shen DD, Sterling ES, Adkins JE, Risler L, Phillips B, Ummenhofer W. Epidural, cerebrospinal fluid, and plasma pharmacokinetics of epidural opioids (part 2): effect of epinephrine. Anesthesiology. 99: 466-75. PMID 12883421 DOI: 10.1097/00000542-200308000-00030 |
0.193 |
|
| 1994 |
Adkison KDK, Artru AA, Powers KM, Shen DD. Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system Journal of Pharmacology and Experimental Therapeutics. 268: 797-805. PMID 8113992 |
0.192 |
|
| 2003 |
Bernards CM, Shen DD, Sterling ES, Adkins JE, Risler L, Phillips B, Ummenhofer W. Epidural, cerebrospinal fluid, and plasma pharmacokinetics of epidural opioids (part 1): differences among opioids. Anesthesiology. 99: 455-65. PMID 12883420 DOI: 10.1097/00000542-200308000-00029 |
0.191 |
|
| 2007 |
Andrew MA, Easterling TR, Carr DB, Shen D, Buchanan ML, Rutherford T, Bennett R, Vicini P, Hebert MF. Amoxicillin pharmacokinetics in pregnant women: modeling and simulations of dosage strategies. Clinical Pharmacology and Therapeutics. 81: 547-56. PMID 17329990 DOI: 10.1038/Sj.Clpt.6100126 |
0.191 |
|
| 1988 |
Semmes RLO, Shen DD. Capillary gas chromatographic assay for valproic acid and its 2-desaturated metabolite in brain and plasma Journal of Chromatography B: Biomedical Sciences and Applications. 432: 185-197. PMID 3146579 DOI: 10.1016/S0378-4347(00)80644-1 |
0.189 |
|
| 1996 |
Pavlin DJ, Coda B, Shen DD, Tschanz J, Nguyen Q, Schaffer R, Donaldson G, Jacobson RC, Chapman CR. Effects of combining propofol and alfentanil on ventilation, analgesia, sedation, and emesis in human volunteers Anesthesiology. 84: 23-37. PMID 8572340 DOI: 10.1097/00000542-199601000-00004 |
0.189 |
|
| 1998 |
Arends RH, Hayashi TG, Luger TJ, Shen DD. Cotreatment with racemic fenfluramine inhibits the development of tolerance to morphine analgesia in rats Journal of Pharmacology and Experimental Therapeutics. 286: 585-592. PMID 9694907 |
0.187 |
|
| 2015 |
Ryu RJ, Eyal S, Easterling TR, Caritis SN, Venkataraman R, Hankins G, Rytting E, Thummel K, Kelly EJ, Risler L, Phillips B, Honaker MT, Shen DD, Hebert MF. Pharmacokinetics of metoprolol during pregnancy and lactation. Journal of Clinical Pharmacology. PMID 26461463 DOI: 10.1002/Jcph.631 |
0.184 |
|
| 2017 |
Airhart SE, Shireman LM, Risler LJ, Anderson GD, Nagana Gowda GA, Raftery D, Tian R, Shen DD, O'Brien KD. An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers. Plos One. 12: e0186459. PMID 29211728 DOI: 10.1371/journal.pone.0186459 |
0.184 |
|
| 1997 |
Scism JL, Powers KM, Artru AA, Chambers AC, Lewis L, Adkison KK, Kalhorn TF, Shen DD. Effects of probenecid on brain-cerebrospinal fluid-blood distribution kinetics of E-δ2-valproic acid in rabbits Drug Metabolism and Disposition. 25: 1337-1346. PMID 9394022 |
0.183 |
|
| 1994 |
Vahter M, Mottet NK, Friberg L, Lind B, Shen DD, Burbacher T. Speciation of Mercury in the Primate Blood and Brain Following Long-Term Exposure to Methyl Mercury Toxicology and Applied Pharmacology. 124: 221-229. PMID 8122267 DOI: 10.1006/taap.1994.1026 |
0.183 |
|
| 2007 |
Kornblau SM, Banker DE, Stirewalt D, Shen D, Lemker E, Verstovsek S, Estrov Z, Faderl S, Cortes J, Beran M, Jackson CE, Chen W, Estey E, Appelbaum FR. Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study. Blood. 109: 2999-3006. PMID 17158228 DOI: 10.1182/blood-2006-08-044446 |
0.182 |
|
| 1992 |
Shen DD, Ojemann GA, Rapport RL, Dills RL, Friel PN, Levy RH. Low and variable presence of valproic acid in human brain. Neurology. 42: 582-5. PMID 1549218 DOI: 10.1212/WNL.42.3.582 |
0.182 |
|
| 2021 |
Perazzolo S, Shen DD, Ho RJY. Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 2: Model for the Drug-combination Nanoparticles. Journal of Pharmaceutical Sciences. PMID 34673094 DOI: 10.1016/j.xphs.2021.10.009 |
0.181 |
|
| 2007 |
Huang W, Kalhorn TF, Baillie M, Shen DD, Thummel KE. Determination of free and total cortisol in plasma and urine by liquid chromatography-tandem mass spectrometry. Therapeutic Drug Monitoring. 29: 215-24. PMID 17417077 DOI: 10.1097/Ftd.0B013E31803D14C0 |
0.18 |
|
| 2015 |
Chapron B, Risler L, Phillips B, Collins C, Thummel K, Shen D. Reversible, time-dependent inhibition of CYP3A-mediated metabolism of midazolam and tacrolimus by telaprevir in human liver microsomes. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, SociéTé Canadienne Des Sciences Pharmaceutiques. 18: 101-11. PMID 25877445 DOI: 10.18433/J3288C |
0.179 |
|
| 2017 |
Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, et al. Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity. Jci Insight. 2. PMID 29202460 DOI: 10.1172/Jci.Insight.95978 |
0.179 |
|
| 2013 |
Poulton EJ, Levy L, Lampe JW, Shen DD, Tracy J, Shuhart MC, Thummel KE, Eaton DL. Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo. Toxicology and Applied Pharmacology. 266: 122-31. PMID 23153560 DOI: 10.1016/J.Taap.2012.10.029 |
0.179 |
|
| 1996 |
Burbacher T, Ellis S, Ferrier C, Mcclure L, Wong M, Grant K, Shen D. Methanol pharmacokinetics and reproductive toxicity in the nonhuman primate Neurotoxicology and Teratology. 18: 334. DOI: 10.1016/S0892-0362(96)90083-5 |
0.179 |
|
| 2000 |
Scism JL, Powers KM, Artru AA, Lewis L, Shen DD. Probenecid-inhibitable efflux transport of valproic acid in the brain parenchymal cells of rabbits: A microdialysis study Brain Research. 884: 77-86. PMID 11082489 DOI: 10.1016/S0006-8993(00)02893-6 |
0.179 |
|
| 2018 |
Kraft JC, McConnachie LA, Koehn J, Kinman L, Sun J, Collier AC, Collins C, Shen DD, Ho RJY. Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29432823 DOI: 10.1016/J.Jconrel.2018.02.003 |
0.178 |
|
| 2024 |
Perazzolo S, Shen DD, Scott AM, Ho RJ. Physiologically based Pharmacokinetic Model Validated to Enable Predictions of Multiple Drugs in a Long-acting Drug-combination Nano-Particles (DcNP): Confirmation with 3 HIV Drugs, Lopinavir, Ritonavir, and Tenofovir in DcNP Products. Journal of Pharmaceutical Sciences. PMID 38382809 DOI: 10.1016/j.xphs.2024.02.018 |
0.177 |
|
| 1990 |
Semmes RLO, Shen DD. Nonlinear Binding of Valproic Acid (VPA) and E-Δ2-Valproic Acid to Rat Plasma Proteins Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 7: 461-467. PMID 2114617 DOI: 10.1023/A:1015804413818 |
0.177 |
|
| 2002 |
Desjardins P, Black P, Papageorge M, Norwood T, Shen DD, Norris L, Ardia A. Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen. European Journal of Clinical Pharmacology. 58: 387-94. PMID 12242597 DOI: 10.1007/S00228-002-0491-0 |
0.177 |
|
| 2018 |
Wagner DJ, Shireman LM, Ahn S, Shen DD, Wang J. Disposition of Methamphetamine and Major Metabolites in Mice: Role of Organic Cation Transporter 3 (Oct3) in Tissue Selective Accumulation of -hydroxymethamphetamine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29915156 DOI: 10.1124/dmd.118.082131 |
0.177 |
|
| 2013 |
Zheng S, Tasnif Y, Hebert MF, Davis CL, Shitara Y, Calamia JC, Lin YS, Shen DD, Thummel KE. CYP3A5 gene variation influences cyclosporine A metabolite formation and renal cyclosporine disposition. Transplantation. 95: 821-7. PMID 23354298 DOI: 10.1097/Tp.0B013E31827E6Ad9 |
0.175 |
|
| 1977 |
Bochner F, Huffman DH, Shen DD, Azarnoff DL. Bioavailability of digoxin-hydroquinone complex: a new oral digoxin formulation. Journal of Pharmaceutical Sciences. 66: 644-7. PMID 874745 DOI: 10.1002/jps.2600660510 |
0.175 |
|
| 2017 |
Liao MZ, Gao C, Shireman LM, Phillips B, Risler LJ, Neradugomma NK, Choudhari P, Prasad B, Shen DD, Mao Q. P-gp/ABCB1 Exerts Differential Impacts On Brain and Fetal Exposure to Norbuprenorphine. Pharmacological Research. PMID 28111265 DOI: 10.1016/j.phrs.2017.01.018 |
0.174 |
|
| 2009 |
Cherrier MM, Amory JK, Ersek M, Risler L, Shen DD. Comparative cognitive and subjective side effects of immediate-release oxycodone in healthy middle-aged and older adults. The Journal of Pain : Official Journal of the American Pain Society. 10: 1038-50. PMID 19729346 DOI: 10.1016/J.Jpain.2009.03.017 |
0.174 |
|
| 2007 |
Reoux JP, Saxon AJ, Shen D. Pharmacokinetic profile of an oral loading dose of divalproex sodium during acute alcohol withdrawal. Journal of Clinical Psychopharmacology. 26: 105-7. PMID 16415725 DOI: 10.1097/01.JCP.0000196416.06729.FE |
0.173 |
|
| 1994 |
Coda B, Brown MC, Schaffer R, Shen D. Epidural Versus Tailored Intravenous Alfentanil in Volunteers Anesthesiology. 81: A982. DOI: 10.1097/00000542-199409001-00981 |
0.173 |
|
| 1995 |
Agura ED, Cleveland Brown M, Schaffer R, Donaldson G, Shen DD. Antiemetic efficacy and pharmacokinetics of intravenous ondansetron infusion during chemotherapy conditioning for bone marrow transplant Bone Marrow Transplantation. 16: 213-222. PMID 7581139 |
0.172 |
|
| 1993 |
Bearman SI, Shen DD, Hinds MS, Hill HA, McDonald GB. A phase I/II study of prostaglandin E1 for the prevention of hepatic venocclusive disease after bone marrow transplantation. British Journal of Haematology. 84: 724-30. PMID 8217833 |
0.172 |
|
| 1995 |
Adkison KD, Artru AA, Powers KM, Nochlin D, Shen DD. Role of choroid plexus epithelium in the removal of valproic acid from the central nervous system. Epilepsy Research. 20: 185-92. PMID 7796790 |
0.171 |
|
| 2018 |
Perazzolo S, Shireman LM, Koehn J, McConnachie LA, Kraft JC, Shen DD, Ho RJY. Three HIV drugs, atazanavir, ritonavir and tenofovir co-formulated in drug-combination nanoparticles exhibit long-acting and lymphocyte targeting properties in non-human primates. Journal of Pharmaceutical Sciences. PMID 30121315 DOI: 10.1016/J.Xphs.2018.07.032 |
0.17 |
|
| 2004 |
Shen DD, Artru AA, Adkison KK. Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics. Advanced Drug Delivery Reviews. 56: 1825-57. PMID 15381336 DOI: 10.1016/j.addr.2004.07.011 |
0.169 |
|
| 1994 |
Artru AA, Adkison KDK, Powers KM, Shen DD. Clearance of valproic acid from cerebrospinal fluid in anesthetized rabbit Journal of Neurosurgical Anesthesiology. 6: 193-200. PMID 7521700 |
0.169 |
|
| 1996 |
Adkison KDK, Powers KM, Artru AA, Shen DD. Effect of para-aminohippurate on the efflux of valproic acid from the central nervous system of the rabbit Epilepsy Research. 23: 95-104. PMID 8964279 DOI: 10.1016/0920-1211(95)00092-5 |
0.167 |
|
| 2013 |
Wang Z, Lin YS, Dickmann LJ, Poulton EJ, Eaton DL, Lampe JW, Shen DD, Davis CL, Shuhart MC, Thummel KE. Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalacia. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1101-16. PMID 23212742 DOI: 10.1002/Jbmr.1839 |
0.167 |
|
| 2005 |
McCune JS, Risler LJ, Phillips BR, Thummel KE, Blough D, Shen DD. Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1074-81. PMID 15821045 DOI: 10.1124/Dmd.104.002279 |
0.166 |
|
| 1980 |
Shen DD, Cunningham JL, Shudo I, Azarnoff DL. Disposition kinetics of disopyramide in patients with renal insufficiency Biopharmaceutics and Drug Disposition. 1: 133-140. PMID 7448340 DOI: 10.1002/bdd.2510010308 |
0.166 |
|
| 2000 |
Erjavec MK, Coda BA, Quynh N, Donaldson G, Risler L, Shen DD. Morphine-fluoxetine interactions in healthy volunteers: Analgesia and side effects Journal of Clinical Pharmacology. 40: 1286-1295. PMID 11075315 |
0.166 |
|
| 2012 |
Crews KR, Gaedigk A, Dunnenberger HM, Klein TE, Shen DD, Callaghan JT, Kharasch ED, Skaar TC. Clinical pharmacogenetics implementation consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype Clinical Pharmacology and Therapeutics. 91: 321-326. PMID 22205192 DOI: 10.1038/clpt.2011.287 |
0.165 |
|
| 2019 |
Loughren MJ, Kharasch ED, Kelton-Rehkopf MC, Syrjala KL, Shen DD. Influence of St. John's Wort on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics, and Clinical Effects: A Randomized Clinical Trial. Anesthesiology. PMID 31794512 DOI: 10.1097/ALN.0000000000003065 |
0.164 |
|
| 2005 |
Burbacher TM, Shen DD, Liberato N, Grant KS, Cernichiari E, Clarkson T. Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal. Environmental Health Perspectives. 113: 1015-21. PMID 16079072 DOI: 10.1289/ehp.7712 |
0.163 |
|
| 2020 |
Perazzolo S, Shireman LM, McConnachie LA, Koehn J, Kinman L, Lee W, Lane S, Collier AC, Shen DD, Ho RJY. Integration of computational and experimental approaches to elucidate mechanisms of first-pass lymphatic drug sequestration and long-acting pharmacokinetics of the injectable triple-HIV drug combination TLC-ART 101. Journal of Pharmaceutical Sciences. PMID 32006525 DOI: 10.1016/J.Xphs.2020.01.016 |
0.162 |
|
| 2010 |
Claessens AJ, Risler LJ, Eyal S, Shen DD, Easterling TR, Hebert MF. CYP2D6 mediates 4-hydroxylation of clonidine in vitro: implication for pregnancy-induced changes in clonidine clearance. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1393-6. PMID 20570945 DOI: 10.1124/dmd.110.033878 |
0.158 |
|
| 1999 |
Gibbs MA, Thummel KE, Shen DD, Kunze KL. Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: Comparison of K1 values and impact of CYP3A5 expression Drug Metabolism and Disposition. 27: 180-187. PMID 9929500 |
0.156 |
|
| 2019 |
Cherrier M, Terman G, Shen D, Shireman L, Saxon A, Simpson T, Kooner P, Wicklander K. COGNITIVE AND SUBJECTIVE EFFECTS OF OXYCODONE IN OLDER ADULTS WITH HEALTHY AND UNHEALTHY ALCOHOL PATTERNS Innovation in Aging. 3: S890-S890. DOI: 10.1093/Geroni/Igz038.3256 |
0.155 |
|
| 2000 |
Lynn AM, Nespeca MK, Bratton SL, Shen DD. Intravenous morphine in postoperative infants: intermittent bolus dosing versus targeted continuous infusions. Pain. 88: 89-95. PMID 11098103 DOI: 10.1016/S0304-3959(00)00313-4 |
0.154 |
|
| 2000 |
Gibbs MA, Baillie MT, Shen DD, Kunze KL, Thummel KE. Persistent inhibition of CYP3A4 by ketoconazole in modified Caco-2 cells. Pharmaceutical Research. 17: 299-305. PMID 10801218 DOI: 10.1023/A:1007550717526 |
0.153 |
|
| 1999 |
Pierce CH, Lewandowski TA, Dills RL, Morgan MS, Wessels MA, Shen DD, Kalman DA. A comparison of 1H8- and 2H8-toluene toxicokinetics in men Xenobiotica. 29: 93-108. PMID 10078842 DOI: 10.1080/004982599238830 |
0.148 |
|
| 1987 |
Kwong EC, Shen DD. Versatile isocratic high-performance liquid chromatographic assay for propranolol and its basic, neutral and acidic metabolites in biological fluids Journal of Chromatography B: Biomedical Sciences and Applications. 414: 365-379. PMID 3571404 DOI: 10.1016/0378-4347(87)80061-0 |
0.148 |
|
| 2014 |
Yeung CK, Shen DD, Thummel KE, Himmelfarb J. Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport. Kidney International. 85: 522-8. PMID 24132209 DOI: 10.1038/Ki.2013.399 |
0.147 |
|
| 1992 |
Shieh SM, Sheu WH, Shen DD, Fuh MM, Jeng CY, Jeng JR, Chen YD, Reaven GM. Improvement in metabolic risk factors for coronary heart disease associated with cilazapril treatment. American Journal of Hypertension. 5: 506-10. PMID 1388960 DOI: 10.1093/ajh/5.8.506 |
0.146 |
|
| 2015 |
Claessens AJ, Yeung CK, Risler LJ, Phillips BR, Himmelfarb J, Shen DD. Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects. Annals of Clinical Biochemistry. PMID 26056391 DOI: 10.1177/0004563215593097 |
0.145 |
|
| 1995 |
Mautz DS, Nelson WL, Shen DD. Regioselective and stereoselective oxidation of metoprolol and bufuralol catalyzed by microsomes containing cDNA-expressed human P4502D6 Drug Metabolism and Disposition. 23: 513-517. PMID 7600921 |
0.145 |
|
| 2000 |
Koszdin KL, Shen DD, Bernards CM. Spinal cord bioavailability of methylprednisolone after intravenous and intrathecal administration: The role of P-glycoprotein Anesthesiology. 92: 156-163. PMID 10638912 |
0.144 |
|
| 2020 |
Chapron A, Chapron BD, Hailey DW, Chang SY, Imaoka T, Thummel KE, Kelly E, Himmelfarb J, Shen D, Yeung CK. An Improved Vascularized, Dual-Channel Microphysiological System Facilitates Modeling of Proximal Tubular Solute Secretion. Acs Pharmacology & Translational Science. 3: 496-508. PMID 32566915 DOI: 10.1021/acsptsci.9b00078 |
0.144 |
|
| 2013 |
Zheng S, Easterling TR, Hays K, Umans JG, Miodovnik M, Clark S, Calamia JC, Thummel KE, Shen DD, Davis CL, Hebert MF. Tacrolimus placental transfer at delivery and neonatal exposure through breast milk. British Journal of Clinical Pharmacology. 76: 988-96. PMID 23528073 DOI: 10.1111/Bcp.12122 |
0.144 |
|
| 2013 |
Kelly EJ, Wang Z, Voellinger JL, Yeung CK, Shen DD, Thummel KE, Zheng Y, Ligresti G, Eaton DL, Muczynski KA, Duffield JS, Neumann T, Tourovskaia A, Fauver M, Kramer G, et al. Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system. Stem Cell Research & Therapy. 4: S17. PMID 24564863 DOI: 10.1186/Scrt378 |
0.143 |
|
| 2016 |
Weber EJ, Chapron A, Chapron BD, Voellinger JL, Lidberg KA, Yeung CK, Wang Z, Yamaura Y, Hailey DW, Neumann T, Shen DD, Thummel KE, Muczynski KA, Himmelfarb J, Kelly EJ. Development of a microphysiological model of human kidney proximal tubule function. Kidney International. 90: 627-37. PMID 27521113 DOI: 10.1016/J.Kint.2016.06.011 |
0.143 |
|
| 1995 |
Naora K, Shen DD. Mechanism of valproic acid uptake by isolated rat brain microvessels Epilepsy Research. 22: 97-106. PMID 8777904 DOI: 10.1016/0920-1211(95)00034-8 |
0.142 |
|
| 1995 |
Mautz DS, Shen DD, Nelson WL. Regioselectivity and Enantioselectivity of Metoprolol Oxidation by Two Variants of cDNA-Expressed P4502D6 Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12: 2053-2056. PMID 8786988 DOI: 10.1023/A:1016233115443 |
0.142 |
|
| 1997 |
Dills RL, Shen DD. Methods to reduce background interferences in electron-capture gas chromatographic analysis of valproic acid and its unsaturated metabolites after derivatization with pentafluorobenzyl bromide Journal of Chromatography B: Biomedical Applications. 690: 139-152. PMID 9106038 DOI: 10.1016/S0378-4347(96)00405-7 |
0.139 |
|
| 2021 |
Perazzolo S, Shireman LM, Shen DD, Ho RJY. Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-drug Mixture. Journal of Pharmaceutical Sciences. PMID 34673093 DOI: 10.1016/j.xphs.2021.10.007 |
0.139 |
|
| 1995 |
Isackson J, Wallace MS, Ho RJ, Shen DD, Yaksh TL. Antinociception and side effects of L- and D-dipalmitoylphosphatidyl choline liposome-encapsulated alfentanil after spinal delivery in rats. Pharmacology & Toxicology. 77: 333-40. PMID 8778746 |
0.138 |
|
| 2022 |
Wang DD, Airhart SE, Zhou B, Shireman LM, Jiang S, Melendez Rodriguez C, Kirkpatrick JN, Shen DD, Tian R, O'Brien KD. Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction. Jacc. Basic to Translational Science. 7: 1183-1196. PMID 36644285 DOI: 10.1016/j.jacbts.2022.06.012 |
0.137 |
|
| 1992 |
Sheu WH, Jeng CY, Shieh SM, Fuh MM, Shen DD, Chen YD, Reaven GM. Insulin resistance and abnormal electrocardiograms in patients with high blood pressure. American Journal of Hypertension. 5: 444-8. PMID 1637516 DOI: 10.1093/ajh/5.7.444 |
0.136 |
|
| 2001 |
Bethune CR, Bernards CM, Bui-Nguyen T, Shen DD, Ho RJY. The role of drug-lipid interactions on the disposition of liposome-formulated opioid analgesics in vitro and in vivo Anesthesia and Analgesia. 93: 928-933. PMID 11574359 |
0.134 |
|
| 2015 |
McAdams RM, McPherson RJ, Kapur R, Phillips B, Shen DD, Juul SE. Dexmedetomidine reduces cranial temperature in hypothermic neonatal rats. Pediatric Research. 77: 772-8. PMID 25751572 DOI: 10.1038/pr.2015.45 |
0.133 |
|
| 1998 |
Lynn A, Nespeca MK, Bratton SL, Strauss SG, Shen DD. Clearance of morphine in postoperative infants during intravenous infusion: the influence of age and surgery. Anesthesia and Analgesia. 86: 958-63. PMID 9585276 DOI: 10.1097/00000539-199805000-00008 |
0.133 |
|
| 2013 |
Dodds M, Chow V, Markus R, Pérez-Ruixo JJ, Shen D, Gibbs M. The use of pharmacometrics to optimize biosimilar development. Journal of Pharmaceutical Sciences. 102: 3908-14. PMID 24027111 DOI: 10.1002/jps.23697 |
0.132 |
|
| 2004 |
Burbacher TM, Grant KS, Shen DD, Sheppard L, Damian D, Ellis S, Liberato N. Chronic maternal methanol inhalation in nonhuman primates (Macaca fascicularis): reproductive performance and birth outcome. Neurotoxicology and Teratology. 26: 639-50. PMID 15315813 DOI: 10.1016/J.Ntt.2004.06.001 |
0.131 |
|
| 1997 |
Coda BA, O'Sullivan B, Donaldson G, Bohl S, Chapman CR, Shen DD. Comparative efficacy of patient-controlled administration of morphine, hydromorphone, or sufentanil for the treatment of oral mucositis pain following bone marrow transplantation Pain. 72: 333-346. PMID 9313274 DOI: 10.1016/S0304-3959(97)00059-6 |
0.131 |
|
| 2017 |
Liao MZ, Gao C, Phillips BR, Neradugomma NK, Han LW, Bhatt DK, Prasad B, Shen DD, Mao Q. Pregnancy Increases Norbuprenorphine Clearance in Mice by Induction of Hepatic Glucuronidation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29158248 DOI: 10.1124/dmd.117.076745 |
0.131 |
|
| 2017 |
Kraft JC, McConnachie LA, Koehn J, Kinman L, Collins C, Shen DD, Collier AC, Ho RJ. Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma. Aids (London, England). PMID 28099191 DOI: 10.1097/Qad.0000000000001405 |
0.131 |
|
| 1996 |
Naora K, Ichikawa N, Nishimura N, Hirano H, Shen DD, Iwamoto K. Saturable transport of valproic acid in rat choroid plexus in vitro Journal of Pharmaceutical Sciences. 85: 423-426. PMID 8901082 DOI: 10.1021/js950436q |
0.13 |
|
| 2003 |
McConnachie LA, Phillips B, Bajpai M, Shen DD, Ho RJ. Only truncated, not complete cytochrome p450 2D6 RNA transcript and no detectable enzyme activity are expressed in human lymphocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1103-7. PMID 12920165 DOI: 10.1124/Dmd.31.9.1103 |
0.129 |
|
| 1983 |
Levine HL, Cohen ME, Duffner PK, Kustas KA, Shen DD. An improved high-pressure liquid chromatographic assay for secobarbital in serum. Journal of Pharmaceutical Sciences. 71: 1281-3. PMID 7175723 DOI: 10.1002/jps.2600711123 |
0.129 |
|
| 2004 |
Yang Z, Horn M, Wang J, Shen DD, Ho RJY. Development and characterization of a recombinant Madin-Darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRPl) Aaps Journal. 6. |
0.128 |
|
| 2004 |
Yang Z, Horn M, Wang J, Shen DD, Ho RJ. Development and characterization of a recombinant Madin-Darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRP1). Aaps Pharmsci. 6: E8. PMID 15198509 DOI: 10.1208/ps060108 |
0.127 |
|
| 2004 |
Yang Z, Horn M, Wang J, Shen DD, Ho RJ. Development and characterization of a recombinant madin-darby canine kidney cell line that expresses rat multidrug resistance-associated protein 1 (rMRP1). The Aaps Journal. 6: 77-85. PMID 18465260 DOI: 10.1208/ps060108 |
0.127 |
|
| 2002 |
Yang Z, Li CS, Shen DD, Ho RJ. Cloning and characterization of the rat multidrug resistance-associated protein 1. Aaps Pharmsci. 4: E15. PMID 12423064 DOI: 10.1208/ps040315 |
0.126 |
|
| 2010 |
Yeung CK, Zhao P, Shen DD, Thummel KE. Drug disposition and drug-drug interactions: Importance of first-pass metabolism in gut and liver Enzyme- and Transporter-Based Drug-Drug Interactions: Progress and Future Challenges. 415-435. DOI: 10.1007/978-1-4419-0840-7_17 |
0.125 |
|
| 1990 |
Bowdle TA, Artru AA, Marathe P, Shen DD. A355 Plasma Protein Binding Determines Partitioning of Lidocaine into Brain and CSF Following Intravenous Bolus Administration in Dogs Anesthesiology. 73: NA. DOI: 10.1097/00000542-199009001-00351 |
0.124 |
|
| 2016 |
Robinson-Cohen C, Newitt R, Shen DD, Rettie AE, Kestenbaum BR, Himmelfarb J, Yeung CK. Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients. Plos One. 11: e0161074. PMID 27513517 DOI: 10.1371/Journal.Pone.0161074 |
0.123 |
|
| 2023 |
Chang SY, Huang W, Chapron A, Quiñones AJL, Wang J, Isoherranen N, Shen DD, Kelly EJ, Himmelfarb J, Yeung CK. Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease. Pharmaceutical Research. PMID 37704895 DOI: 10.1007/s11095-023-03594-x |
0.123 |
|
| 1996 |
Bajpai M, Roskos LK, Shen DD, Levy RH. Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite Drug Metabolism and Disposition. 24: 1401-1403. PMID 8971149 |
0.121 |
|
| 2015 |
Yeung CK, Billings FT, Claessens AJ, Roshanravan B, Linke L, Sundell MB, Ahmad S, Shao B, Shen DD, Ikizler TA, Himmelfarb J. Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress. Bmc Nephrology. 16: 183. PMID 26531095 DOI: 10.1186/S12882-015-0178-2 |
0.121 |
|
| 2000 |
Ummenhofer WC, Arends RH, Shen DD, Bernards CM. Comparative spinal distribution and clearance kinetics of intrathecally administered morphine, fentanyl, alfentanil, and sufentanil Anesthesiology. 92: 739-753. PMID 10719953 |
0.119 |
|
| 2004 |
McConnachie L, Bodor M, Kowdley K, Levy A, Tung B, Thummel K, Phillips B, Bajpai M, Chi V, Esmay JD, Shen DD, Ho RJ. Human liver cytochrome P450 2D6 genotype, full-length messenger ribonucleic acid, and activity assessed with a novel cytochrome P450 2D6 substrate. Clinical Pharmacology and Therapeutics. 75: 282-97. PMID 15060507 DOI: 10.1016/J.Clpt.2003.12.003 |
0.118 |
|
| 2009 |
Salinger DH, Shen DD, Thummel K, Wittkowsky AK, Vicini P, Veenstra DL. Pharmacogenomic trial design: use of a PK/PD model to explore warfarin dosing interventions through clinical trial simulation. Pharmacogenetics and Genomics. 19: 965-71. PMID 19881396 DOI: 10.1097/Fpc.0B013E3283333B80 |
0.116 |
|
| 2000 |
Coda BA, Syrjala KL, Roth-Roemer S, Shen DD, Shen D. Room 310, 10/17/2000 10: 30 AM - 12: 00 PM (PD) Cognitive and Motor Effects of Morphine and Hydromorphone at Equianalgesic Plasma Concentrations Anesthesiology. 93: A-966. DOI: 10.1097/00000542-200009001-00966 |
0.115 |
|
| 2000 |
Nishiyama T, Ho RJ, Shen DD, Yaksh TL. The effects of intrathecal morphine encapsulated in L- and D-dipalmitoylphosphatidyl choline liposomes on acute nociception in rats. Anesthesia and Analgesia. 91: 423-8. PMID 10910861 |
0.114 |
|
| 1996 |
Adkison KDK, Shen DD. Uptake of valproic acid into rat brain is mediated by a medium-chain fatty acid transporter Journal of Pharmacology and Experimental Therapeutics. 276: 1189-1200. PMID 8786552 |
0.114 |
|
| 2004 |
Gibbs JP, Adeyeye MC, Yang Z, Shen DD. Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport. Epilepsy Research. 58: 53-66. PMID 15066675 DOI: 10.1016/j.eplepsyres.2003.12.008 |
0.114 |
|
| 2006 |
Li M, Anderson GD, Phillips BR, Kong W, Shen DD, Wang J. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 547-55. PMID 16434549 DOI: 10.1124/dmd.105.006791 |
0.112 |
|
| 1994 |
Sheu WH, Shieh SM, Shen DD, Fuh MM, Jeng CY, Chen YD, Reaven GM. Effect of pravastatin treatment on glucose, insulin, and lipoprotein metabolism in patients with hypercholesterolemia. American Heart Journal. 127: 331-6. PMID 8296701 DOI: 10.1016/0002-8703(94)90121-X |
0.111 |
|
| 2011 |
Shen DD, Zhang T, Huang H. Preparation and in vitro transdermal penetration of oxybutynin hydrochloride ethosome Journal of China Pharmaceutical University. 42: 48-52. |
0.111 |
|
| 2015 |
Vogel KR, Ainslie GR, Phillips B, Arning E, Bottiglieri T, Shen DD, Gibson KM. Physiological Competition of Brain Phenylalanine Accretion: Initial Pharmacokinetic Analyses of Aminoisobutyric and Methylaminoisobutyric Acids in Pah(enu2-/-) Mice. Molecular Genetics and Metabolism Reports. 3: 80-87. PMID 26120559 DOI: 10.1016/J.Ymgmr.2015.03.009 |
0.11 |
|
| 1994 |
Hautman B, Coda B, Bohl S, Donaldson G, Shen D. Analgesic and Side Effects of Patient-controlled Analgesia with Morphine, Hydromorphone, and Sufentanil for Oral Mucositis Anesthesiology. 81: A1001. DOI: 10.1097/00000542-199409001-01000 |
0.108 |
|
| 2015 |
Li JX, Yin Y, Ren G, Yuan L, Li PR, Shen DD. Observational study of the spatial-temporal distribution of cloud condensation nuclei in Shanxi Province, China Zhongguo Huanjing Kexue/China Environmental Science. 35: 2261-2271. |
0.107 |
|
| 2010 |
Yue ZH, Shen DD, Hu CQ. The compatibility between packing material and ipratropium bromide aerosol Yaoxue Xuebao. 45: 1035-1038. PMID 21351591 |
0.105 |
|
| 2018 |
Paine MF, Shen DD, McCune JS. Recommended Approaches for Pharmacokinetic Natural Product-Drug Interaction Research: a NaPDI Center Commentary. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29735755 DOI: 10.1124/dmd.117.079962 |
0.105 |
|
| 1984 |
Jeng CY, Bian TY, Shian LR, Huang HW, Shen DD, Liu PH. A comparative study of the short therapeutic effect of amiodarone and iodine on Graves' thyrotoxicosis Journal of the Formosan Medical Association. 83: 1238-1246. PMID 6597854 |
0.104 |
|
| 1997 |
Burbacher T, Grant K, Shen D. Reproductive and offspring developmental effects of inhaled methanol in nonhuman primates Neurotoxicology and Teratology. 19: 244-245. DOI: 10.1016/S0892-0362(97)82408-7 |
0.103 |
|
| 2002 |
Sachdeo RC, Sachdeo SK, Levy RH, Streeter AJ, Bishop FE, Kunze KL, Mather GG, Roskos LK, Shen DD, Thummel KE, Trager WF, Curtin CR, Doose DR, Gisclon LG, Bialer M. Topiramate and phenytoin pharmacokinetics during repetitive monotherapy and combination therapy to epileptic patients. Epilepsia. 43: 691-6. PMID 12102670 DOI: 10.1046/J.1528-1157.2002.41701.X |
0.103 |
|
| 1989 |
Laganière S, Kwong E, Shen DD. Stereoselective high-performance liquid chromatographic assay for propranolol enantiomers in serum Journal of Chromatography B: Biomedical Sciences and Applications. 488: 407-416. PMID 2745631 DOI: 10.1016/S0378-4347(00)82964-3 |
0.102 |
|
| 2021 |
Cherrier MM, Shen DD, Shireman L, Saxon AJ, Simpson T, Men A, Kooner P, Terman GW. Elevated customary alcohol consumption attenuates opioid effects. Pharmacology, Biochemistry, and Behavior. 173295. PMID 34742948 DOI: 10.1016/j.pbb.2021.173295 |
0.101 |
|
| 2018 |
Chapron BD, Chapron A, Phillips B, Okoli MC, Shen DD, Kelly EJ, Himmelfarb J, Thummel KE. Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system. Altex. PMID 29999169 DOI: 10.14573/Altex.1803161 |
0.099 |
|
| 2014 |
Crews KR, Gaedigk A, Dunnenberger HM, Leeder JS, Klein TE, Caudle KE, Haidar CE, Shen DD, Callaghan JT, Sadhasivam S, Prows CA, Kharasch ED, Skaar TC. Clinical pharmacogenetics implementation consortium guidelines for cytochrome P450 2D6 genotype and codeine therapy: 2014 Update Clinical Pharmacology and Therapeutics. 95: 376-382. PMID 24458010 DOI: 10.1038/clpt.2013.254 |
0.096 |
|
| 2016 |
Zheng YC, Wang LZ, Zhao LJ, Zhao LJ, Zhan QN, Ma JL, Zhang B, Wang MM, Wang ZR, Li JF, Liu Y, Chen ZS, Shen DD, Liu XQ, Ren M, et al. 1,2,3-Triazole-Dithiocarbamate Hybrids, a Group of Novel Cell Active SIRT1 Inhibitors. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 185-193. PMID 26784898 DOI: 10.1159/000438620 |
0.096 |
|
| 2015 |
Chan LN, Lin YS, Tay-Sontheimer JC, Trawick D, Oelschlager BK, Flum DR, Patton KK, Shen DD, Horn JR. Proximal Roux-en-Y gastric bypass alters drug absorption pattern but not systemic exposure of CYP3A4 and P-glycoprotein substrates. Pharmacotherapy. 35: 361-9. PMID 25757445 DOI: 10.1002/Phar.1560 |
0.096 |
|
| 2007 |
Chen Y, Kuehl GE, Bigler J, Rimorin CF, Schwarz Y, Shen DD, Lampe JW. UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin. Pharmacogenetics and Genomics. 17: 571-9. PMID 17622933 DOI: 10.1097/01.Fpc.0000236339.79916.07 |
0.095 |
|
| 2018 |
Johnson EJ, Gonzalez-Perez V, Tian DD, Lin YS, Unadkat JD, Rettie AE, Shen DD, McCune JS, Paine MF. Selection of Priority Natural Products for Evaluation as Potential Precipitants of Natural Product-Drug Interactions: a NaPDI Center Recommended Approach. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29735752 DOI: 10.1124/Dmd.118.081273 |
0.094 |
|
| 2007 |
Anderson GD, Shen DD. Where is the evidence that p-glycoprotein limits brain uptake of antiepileptic drug and contributes to drug resistance in epilepsy? Epilepsia. 48: 2372-4. PMID 18088270 DOI: 10.1111/j.1528-1167.2007.01260_3.x |
0.094 |
|
| 2004 |
Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJ. Multidrug resistance gene G1199A polymorphism alters efflux transport activity of P-glycoprotein. The Journal of Pharmacology and Experimental Therapeutics. 310: 1199-207. PMID 15100388 DOI: 10.1124/Jpet.104.065383 |
0.094 |
|
| 2019 |
Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Hong Wong L, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, et al. Interrogation of CYP2D6 structural variant alleles improves the correlation between CYP2D6 genotype and CYP2D6-mediated metabolic activity. Clinical and Translational Science. PMID 31536170 DOI: 10.1111/Cts.12695 |
0.093 |
|
| 2003 |
Lynn AM, Nespeca MK, Bratton SL, Shen DD. Ventilatory effects of morphine infusions in cyanotic versus acyanotic infants after thoracotomy. Paediatric Anaesthesia. 13: 12-7. PMID 12535033 DOI: 10.1046/j.1460-9592.2003.00959.x |
0.093 |
|
| 2017 |
Liao MZ, Shen DD, Mao Q. P-gp/ABCB1 Exerts Differential Impacts On Brain and Fetal Exposure to Norbuprenorphine - Response to 'Letter to the Editor'. Pharmacological Research. PMID 28411002 DOI: 10.1016/j.phrs.2017.04.007 |
0.093 |
|
| 2007 |
DuPen A, Shen D, Ersek M. Mechanisms of opioid-induced tolerance and hyperalgesia. Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses. 8: 113-21. PMID 17723928 DOI: 10.1016/J.Pmn.2007.02.004 |
0.09 |
|
| 1995 |
Yanez AM, Wallace M, Ho R, Shen D, Yaksh TL. Touch-evoked agitation produced by spinally administered phospholipid emulsion and liposomes in rats. Structure-activity relation. Anesthesiology. 82: 1189-98. PMID 7741294 DOI: 10.1097/00000542-199505000-00014 |
0.09 |
|
| 1993 |
Sheu WH, Shieh SM, Fuh MM, Shen DD, Jeng CY, Chen YD, Reaven GM. Insulin resistance, glucose intolerance, and hyperinsulinemia. Hypertriglyceridemia versus hypercholesterolemia. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 13: 367-70. PMID 8443140 DOI: 10.1161/01.ATV.13.3.367 |
0.088 |
|
| 2014 |
Liu YQ, Shen DD, Wu Q, Lin Y, Tang Q. Comparative study on dissolution profiles of meleumycin tablets from different manufacturers in five dissolution medias Chinese Journal of Antibiotics. 1: S2-S4. |
0.087 |
|
| 2000 |
Wrighton SA, Schuetz EG, Thummel KE, Shen DD, Korzekwa KR, Watkins PB. The human CYP3A subfamily: Practical considerations Drug Metabolism Reviews. 32: 339-361. PMID 11139133 DOI: 10.1081/Dmr-100102338 |
0.086 |
|
| 1978 |
Shen DD, Azarnoff DL. Clinical pharmacokinetics of methotrexate. Clinical Pharmacokinetics. 3: 1-13. PMID 346283 DOI: 10.2165/00003088-197803010-00001 |
0.085 |
|
| 2019 |
Shuster DL, Shireman LM, Ma X, Shen DD, Flood Nichols SK, Ahmed MS, Clark S, Caritis S, Venkataramanan R, Haas DM, Quinney SK, Haneline LS, Tita AT, Manuck TA, Thummel KE, et al. Pharmacodynamics of glyburide, metformin and glyburide/metformin combination therapy in the treatment of gestational diabetes mellitus. Clinical Pharmacology and Therapeutics. PMID 31869430 DOI: 10.1002/Cpt.1749 |
0.084 |
|
| 2010 |
Choueiter NF, Olson AK, Shen DD, Portman MA. Prospective open-label trial of etanercept as adjunctive therapy for kawasaki disease. The Journal of Pediatrics. 157: 960-966.e1. PMID 20667551 DOI: 10.1016/j.jpeds.2010.06.014 |
0.083 |
|
| 2015 |
Vogel KR, Ainslie GR, Phillips B, Arning E, Bottiglieri T, Shen DD, Gibson KM. Physiological competition of brain phenylalanine accretion: Initial pharmacokinetic analyses of aminoisobutyric and methylaminoisobutyric acids in Pahenu2 -/- mice Molecular Genetics and Metabolism Reports. 3: 80-87. DOI: 10.1016/j.ymgmr.2015.03.009 |
0.083 |
|
| 2012 |
Jimenez N, Anderson GD, Shen DD, Nielsen SS, Farin FM, Seidel K, Lynn AM. Is ethnicity associated with morphine's side effects in children? Morphine pharmacokinetics, analgesic response, and side effects in children having tonsillectomy. Paediatric Anaesthesia. 22: 669-75. PMID 22486937 DOI: 10.1111/j.1460-9592.2012.03844.x |
0.081 |
|
| 2020 |
Yu J, Mu Q, Perazzolo S, Griffin JI, Zhu L, McConnachie LA, Shen DD, Ho RJ. Novel Long-Acting Drug Combination Nanoparticles Composed of Gemcitabine and Paclitaxel Enhance Localization of Both Drugs in Metastatic Breast Cancer Nodules. Pharmaceutical Research. 37: 197. PMID 32968837 DOI: 10.1007/s11095-020-02888-8 |
0.08 |
|
| 2005 |
Shen DD, Song SH, Yuan ZX, Weng LQ. Effect of solute grain boundary segregation and hardness on the ductile-to-brittle transition for a Cr-Mo low-alloy steel Materials Science and Engineering A. 394: 53-59. DOI: 10.1016/j.msea.2004.10.036 |
0.08 |
|
| 2012 |
Zheng S, Easterling TR, Umans JG, Miodovnik M, Calamia JC, Thummel KE, Shen DD, Davis CL, Hebert MF. Pharmacokinetics of tacrolimus during pregnancy. Therapeutic Drug Monitoring. 34: 660-70. PMID 23007747 DOI: 10.1097/Ftd.0B013E3182708Edf |
0.08 |
|
| 2020 |
Cherrier MM, Shireman LM, Wicklander K, Yeung W, Kooner P, Saxon AJ, Simpson T, Terman G, Shen D. Relationship of Phosphatidylethanol (PEth) Biomarker to Self-Reported Alcohol Drinking Patterns in Older and Middle Age Adults. Alcoholism, Clinical and Experimental Research. PMID 33038267 DOI: 10.1111/acer.14475 |
0.079 |
|
| 1996 |
Wu DA, Bu X, Warden CH, Shen DD, Jeng CY, Sheu WH, Fuh MM, Katsuya T, Dzau VJ, Reaven GM, Lusis AJ, Rotter JI, Chen YD. Quantitative trait locus mapping of human blood pressure to a genetic region at or near the lipoprotein lipase gene locus on chromosome 8p22. The Journal of Clinical Investigation. 97: 2111-8. PMID 8621801 DOI: 10.1172/Jci118648 |
0.077 |
|
| 2012 |
Bell GA, Kantor ED, Lampe JW, Shen DD, White E. Use of glucosamine and chondroitin in relation to mortality. European Journal of Epidemiology. 27: 593-603. PMID 22828954 DOI: 10.1007/S10654-012-9714-6 |
0.076 |
|
| 1994 |
Isackson J, Wallace M, Ho RJY, Shen D, Yaksh T. Antinociception and Side Effects of L and D Isomer Liposome-encapsulated Alfentanil after Spinal Delivery in Rats Anesthesiology. 81: A915. DOI: 10.1097/00000542-199409001-00914 |
0.075 |
|
| 2012 |
Suresh MV, Wagner MC, Rosania GR, Stringer KA, Min KA, Risler L, Shen DD, Georges GE, Reddy AT, Parkkinen J, Reddy RC. Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury American Journal of Respiratory Cell and Molecular Biology. 47: 280-287. PMID 22312018 DOI: 10.1165/Rcmb.2011-0175Oc |
0.072 |
|
| 2002 |
Yang Z, Woodahl EL, Wang XY, Bui T, Shen DD, Ho RJY. Semi-quantitative RT-PCR method to estimate full-length mRNA levels of the multidrug resistance gene Biotechniques. 33: 196-203. PMID 12139246 DOI: 10.2144/02331Dd03 |
0.07 |
|
| 2008 |
Wang Y, Shen DD, Wang ZY, Sun LW, Zhu JT. Study on the synthesis of R)- and (S)-acebutolol Gao Xiao Hua Xue Gong Cheng Xue Bao/Journal of Chemical Engineering of Chinese Universities. 22: 860-865. |
0.068 |
|
| 2003 |
Song SH, Yuan ZX, Jia J, Guo AM, Shen DD. The role of tin in the hot-ductility deterioration of a low-carbon steel Metallurgical and Materials Transactions a: Physical Metallurgy and Materials Science. 34: 1611-1616. |
0.068 |
|
| 1978 |
Cunningham JL, Shen DD, Shudo I, Azarnoff DL. The effect of non-linear disposition kinetics on the systemic availability of disopyramide British Journal of Clinical Pharmacology. 5: 343-346. DOI: 10.1111/j.1365-2125.1978.tb01719.x |
0.067 |
|
| 2009 |
Woodahl EL, Crouthamel MH, Bui T, Shen DD, Ho RJ. MDR1 (ABCB1) G1199A (Ser400Asn) polymorphism alters transepithelial permeability and sensitivity to anticancer agents. Cancer Chemotherapy and Pharmacology. 64: 183-8. PMID 19123050 DOI: 10.1007/S00280-008-0906-4 |
0.059 |
|
| 2015 |
Shen DD, Ji ZG. Mechanoluminescence of persistent luminescent SrAl2O4: (Eu2+, Dy3+) material prepared by electron beam reduction Wuji Cailiao Xuebao/Journal of Inorganic Materials. 30: 93-96. DOI: 10.15541/jim20140198 |
0.058 |
|
| 2019 |
Shuster DL, Shireman LM, Ma X, Shen DD, Flood Nichols SK, Ahmed MS, Clark S, Caritis S, Venkataramanan R, Haas DM, Quinney SK, Haneline LS, Tita AT, Manuck TA, Thummel KE, et al. Pharmacodynamics of Metformin in Pregnant Women With Gestational Diabetes Mellitus and Nonpregnant Women With Type 2 Diabetes Mellitus. Journal of Clinical Pharmacology. PMID 31742716 DOI: 10.1002/Jcph.1549 |
0.058 |
|
| 2005 |
Woodahl EL, Yang Z, Bui T, Shen DD, Ho RJ. MDR1 G1199A polymorphism alters permeability of HIV protease inhibitors across P-glycoprotein-expressing epithelial cells. Aids (London, England). 19: 1617-25. PMID 16184031 DOI: 10.1097/01.Aids.0000183626.74299.77 |
0.057 |
|
| 2016 |
Rivara MB, Yeung CK, Robinson-Cohen C, Phillips BR, Ruzinski J, Rock D, Linke L, Shen DD, Ikizler TA, Himmelfarb J. Effect of Coenzyme Q10 on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ10 Biomarker Trial. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 27927588 DOI: 10.1053/J.Ajkd.2016.08.041 |
0.057 |
|
| 2004 |
McConnachie LA, Bodor M, Phillips B, Kelly EJ, Shen DD, Ho RJ. An RT-PCR-based strategy to estimate full-length CYP2D6 mRNA copy number. Genetic Testing. 8: 313-8. PMID 15727256 DOI: 10.1089/Gte.2004.8.313 |
0.056 |
|
| 2000 |
Scarlett LA, Madani S, Shen DD, Ho RJY. Development and characterization of a rapid and comprehensive genotyping assay to detect the most common variants in cytochrome P450 2D6 Pharmaceutical Research. 17: 242-246. PMID 10751042 DOI: 10.1023/A:1007585801905 |
0.056 |
|
| 2003 |
Yuan ZX, Guo AM, Chen S, Shen DD, Jia J, Song SH. Critical time for non-equilibrium grain boundary segregation of antimony in a manganese structural steel Journal of Materials Science Letters. 22: 311-313. DOI: 10.1023/A:1022372817391 |
0.054 |
|
| 2013 |
Gui LL, Hong M, Wang HZ, Shen DD, Wei X, Hua YQ. A mouse model of TSLP production based on Th2 cell-mediated allergic inflammation Chinese Pharmacological Bulletin. 29: 1473-1474. DOI: 10.3969/j.issn.1001-1978.2013.10.034 |
0.053 |
|
| 2012 |
Shen DD, Zhu R, Xu WW, Chang JJ, Ji ZM, Sun GZ, Cao CH, Chen J. Character and fabrication of Al/Al 2O 3/Al tunnel junctions for qubit application Chinese Science Bulletin. 57: 409-412. DOI: 10.1007/s11434-011-4821-4 |
0.052 |
|
| 2014 |
Shen DD, Zheng Q. The key construction techniques of long span continuous rigid frame bridge of the expressway in mountain areas Advanced Materials Research. 1055: 127-130. DOI: 10.4028/www.scientific.net/AMR.1055.127 |
0.05 |
|
| 1997 |
Pavlin J, Gunn H, Van Norman G, Arends R, Shen D, Koerschgen M. A308 OPTIMAL PROFOFOL/ALFENTANIL COMBINATIONS FOR SUPPLEMENTING N sub 2 O FOR OUTPATIENTS SURGERY Anesthesiology. 87: 308A. DOI: 10.1097/00000542-199709001-00308 |
0.05 |
|
| 2003 |
Song SH, Guo AM, Shen DD, Yuan ZX, Liu J, Xu TD. Effect of boron on the hot ductility of 2.25Cr1Mo steel Materials Science and Engineering A. 360: 96-100. DOI: 10.1016/S0921-5093(03)00438-6 |
0.046 |
|
| 2005 |
Szot P, White SS, Shen DD, Anderson GD. Valproic acid, but not lamotrigine, suppresses seizure-induced c-fos and c-Jun mRNA expression. Brain Research. Molecular Brain Research. 135: 285-9. PMID 15857691 DOI: 10.1016/j.molbrainres.2004.11.011 |
0.046 |
|
| 2004 |
Song SH, Yuan ZX, Shen DD, Liu J, Weng LQ. Grain boundary segregation of phosphorus and molybdenum in a Cr-Mo low alloy steel Materials Science and Technology. 20: 117-120. DOI: 10.1179/026708304225010307 |
0.044 |
|
| 2003 |
Yuan ZX, Jia J, Guo AM, Shen DD, Song SH, Liu J. Influence of tin on the hot ductility of a low-carbon steel Acta Metallurgica Sinica (English Letters). 16: 478-482. |
0.044 |
|
| 2003 |
Song SH, Shen DD, Yuan ZX, Liu J, Xu TD, Weng LQ. Combined equilibrium and non-equilibrium phosphorus segregation to grain boundaries in a 2.25Cr1Mo steel Scripta Materialia. 49: 473-476. DOI: 10.1016/S1359-6462(03)00287-2 |
0.042 |
|
| 2003 |
Guo AM, Wang YH, Shen DD, Yuan ZX, Song SH. Influence of phosphorus on the hot ductility of 2.25Cr1Mo steel Materials Science and Technology. 19: 1553-1556. DOI: 10.1179/026708303225007933 |
0.041 |
|
| 2004 |
Shen DD, Yuan ZX, Liu J, Song SH, Wen LQ. Phosphorus grain boundary segregation in a P-doped 2.25CrlMo steel Acta Metallurgica Sinica (English Letters). 17: 639-644. |
0.041 |
|
| 2013 |
Kantor ED, Ulrich CM, Owen RW, Schmezer P, Neuhouser ML, Lampe JW, Peters U, Shen DD, Vaughan TL, White E. Specialty supplement use and biologic measures of oxidative stress and DNA damage. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 22: 2312-22. PMID 23917455 DOI: 10.1158/1055-9965.Epi-13-0470 |
0.04 |
|
| 2003 |
Yuan ZX, Jia J, Guo AM, Shen DD, Song SH. Cooling-induced tin segregation to grain boundaries in a low-carbon steel Scripta Materialia. 48: 203-206. DOI: 10.1016/S1359-6462(02)00357-3 |
0.04 |
|
| 2014 |
Wang MQ, Yu HL, Chen MJ, Shen DD, Hui JM, Geng QH. Experimental study on the pyrolysis and combustion of municipal sewage sludge Shanghai Ligong Daxue Xuebao/Journal of University of Shanghai For Science and Technology. 36. DOI: 10.13255/j.cnki.jusst.2014.02.015 |
0.04 |
|
| 1985 |
SHEN D, MILSAP R, GEORGITIS J. 325 Pharmacodynamics of brompheniramine and pseudoephedrine in treatment of perennial rhinitis Journal of Allergy and Clinical Immunology. 75: 186. DOI: 10.1016/0091-6749(85)90460-9 |
0.037 |
|
| 2007 |
Wang Y, Shen DD, Zhu JT. Asymmetric synthesis of S- and R-propranolols Chinese Journal of Organic Chemistry. 27: 678-681. |
0.036 |
|
| 2013 |
Kantor ED, Lampe JW, Peters U, Shen DD, Vaughan TL, White E. Use of glucosamine and chondroitin supplements and risk of colorectal cancer. Cancer Causes & Control : Ccc. 24: 1137-46. PMID 23529472 DOI: 10.1007/S10552-013-0192-2 |
0.033 |
|
| 2005 |
Jin BS, Huang ZQ, Shen DD. Influence of isothermal quenching of LAMC CrMnSi cast steel on impact toughness Journal of Central South University of Technology (English Edition). 12: 35-38. |
0.032 |
|
| 2009 |
Zhu YH, Shen DD, Wu WD, Shen ZW, Tang YP. Dynamic routing algorithms optimizing lifetime of wireless sensor networks Tien Tzu Hsueh Pao/Acta Electronica Sinica. 37: 1041-1045. |
0.032 |
|
| 2014 |
Roth GA, Gillespie CW, Mokdad AA, Shen DD, Fleming DW, Stergachis A, Murray CJ, Mokdad AH. Aspirin use and knowledge in the community: a population- and health facility based survey for measuring local health system performance. Bmc Cardiovascular Disorders. 14: 16. PMID 24507089 DOI: 10.1186/1471-2261-14-16 |
0.031 |
|
| 2016 |
Nguyen VHV, Wong BM, Shen DD, Woo DT, Vu AV, Lie JD. Early management of acute ischemic stroke: Focus on IV tPA and timely reperfusion U.S. Pharmacist. 41: HS9-HS12. |
0.031 |
|
| 2015 |
Lie JD, Tu KN, Shen DD, Wong BM. Pharmacological treatment of insomnia P and T. 40: 759-771. |
0.03 |
|
| 2002 |
Xiang MS, Zhang SB, Zhang KY, Shen DD, Shen CW. Control technique for construction of long span prestressed concrete bridge Zhongguo Gonglu Xuebao/China Journal of Highway and Transport. 15: 38. |
0.029 |
|
| 2003 |
Li Xh, Shen Dd, Li N, Yu SS. Bioactive triterpenoids from Symplocos chinensis Journal of Asian Natural Products Research. 5: 49-56. PMID 12608639 DOI: 10.1080/1028602031000080469 |
0.027 |
|
| 2005 |
Shen DD, Li B, Li QF. Study on wear resistance cast iron guide with high chromium molybdenum Zhuzao Jishu/Foundry Technology. 26: 59-61. |
0.026 |
|
| 2012 |
Han K, Chen CC, Shen DD, Pan F, Fang QQ, Weng CX, Zhou XY. An accurate 2-D nonuniform fast Fourier transform method applied to high resolution SAR image reconstruction Proceedings of the 2012 International Workshop On Metamaterials, Meta 2012. DOI: 10.1109/META.2012.6464954 |
0.021 |
|
| 2006 |
Mansour AM, Chan CC, Crawford MA, Tabbarah ZA, Shen D, Haddad WF, Salti I, Ghazi NG. Virus-induced chalazion. Eye (London, England). 20: 242-6. PMID 15746955 DOI: 10.1038/sj.eye.6701816 |
0.019 |
|
| 2003 |
Yuan ZX, Guo AM, Liu J, Shen DD, Jia J, Song SH. Antimony grain boundary segregation and its suppression by cerium in Fe-2%Mn-Sb structural steels Acta Metallurgica Sinica (English Letters). 16: 175-182. |
0.016 |
|
| 2020 |
Cherrier M, Terman G, Shen D, Shireman L, Saxon A, Simpson T. LETTER TO THE EDITOR. The Journal of the American Osteopathic Association. 120: 434-435. PMID 32598456 DOI: 10.7556/jaoa.2020.070 |
0.013 |
|
| 2002 |
Shen DD, Jin BS, Guo JW, Xu ZJ. Study and application of the unalloyed austempered ductile iron disc harrow Zhuzao/Foundry. 51: 352. |
0.012 |
|
| 2010 |
Shen DD. Ideas know no borders Pharmaceutical Technology. 34: 12. |
0.01 |
|
| 2004 |
Ho RJY, Shen DD. Preface Current Drug Metabolism. 5. |
0.01 |
|
| 2001 |
Nishiyama T, Ho RJ, Shen DD, Yaksh TL. Basic Science (22) Pain Practice. 1: 91-92. DOI: 10.1111/j.1533-2500.2001.1011-22.x |
0.01 |
|
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