Alan N. Schechter, M.D. - Publications

Affiliations: 
Georgetown University Medical Center, Washington, DC, United States 
Area:
Medical Biophysics, Human Development, Genetics
Website:
https://irp.nih.gov/pi/alan-schechter

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Srihirun S, Schechter AN, Piknova B. Platelet-based Detection of Nitric Oxide in Blood by Measuring VASP Phosphorylation. Journal of Visualized Experiments : Jove. PMID 30663683 DOI: 10.3791/58647  0.317
2016 Piknova B, Park JW, Cassel KS, Gilliard CN, Schechter AN. Measuring Nitrite and Nitrate, Metabolites in the Nitric Oxide Pathway, in Biological Materials using the Chemiluminescence Method. Journal of Visualized Experiments : Jove. PMID 28060334 DOI: 10.3791/54879  0.314
2016 Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim-Shapiro DB, Lajous M, Larsen FJ, Lefer DJ, McClure LA, Nolan BT, Pluta R, Schechter A, Wang CY, Ward MH, et al. Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop. Journal of the American Heart Association. 5. PMID 27385425 DOI: 10.1161/Jaha.116.003402  0.417
2016 Subotički T, Ajtić OM, Beleslin-Čokić BB, Nienhold R, Diklić M, Đikić D, Leković D, Bulat T, Marković D, Gotić M, Noguchi CT, Schechter AN, Skoda RC, Čokić VP. Angiogenic factors are increased in circulating granulocytes and CD34(+) cells of myeloproliferative neoplasms. Molecular Carcinogenesis. PMID 27341002 DOI: 10.1002/Mc.22517  0.31
2014 Park JW, Piknova B, Nghiem K, Lozier JN, Schechter AN. Inhibitory effect of nitrite on coagulation processes demonstrated by thrombelastography. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 40: 45-51. PMID 24858214 DOI: 10.1016/J.Niox.2014.05.006  0.33
2014 Akrawinthawong K, Park JW, Piknova B, Sibmooh N, Fucharoen S, Schechter AN. A flow cytometric analysis of the inhibition of platelet reactivity due to nitrite reduction by deoxygenated erythrocytes. Plos One. 9: e92435. PMID 24642865 DOI: 10.1371/Journal.Pone.0092435  0.3
2013 Meier ER, Byrnes C, Lee YT, Wright EC, Schechter AN, Luban NL, Miller JL. Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life. Plos One. 8: e70794. PMID 23951011 DOI: 10.1371/Journal.Pone.0070794  0.303
2013 Wang D, Piknova B, Solomon SB, Cortes-Puch I, Kern SJ, Sun J, Kanias T, Gladwin MT, Helms C, Kim-Shapiro DB, Schechter AN, Natanson C. In vivo reduction of cell-free methemoglobin to oxyhemoglobin results in vasoconstriction in canines. Transfusion. 53: 3149-63. PMID 23488474 DOI: 10.1111/Trf.12162  0.49
2013 Park JW, Piknova B, Huang PL, Noguchi CT, Schechter AN. Effect of blood nitrite and nitrate levels on murine platelet function. Plos One. 8: e55699. PMID 23383344 DOI: 10.1371/Journal.Pone.0055699  0.317
2013 Tiso M, Schechter AN. P59: Enteric bacterial nitrate/nitrite/nitric oxide/ammonia metabolism Nitric Oxide. 31. DOI: 10.1016/J.Niox.2013.02.061  0.319
2012 Qazi MA, Rizzatti F, Piknova B, Sibmooh N, Stroncek DF, Schechter AN. Effect of storage levels of nitric oxide derivatives in blood components. F1000research. 1: 35. PMID 24358838 DOI: 10.1182/Blood.V110.11.2884.2884  0.332
2012 Solomon SB, Bellavia L, Sweeney D, Piknova B, Perlegas A, Helms CC, Ferreyra GA, Bruce King S, Raat NJ, Kern SJ, Sun J, McPhail LC, Schechter AN, Natanson C, Gladwin MT, et al. Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin. Free Radical Biology & Medicine. 53: 2229-39. PMID 23099417 DOI: 10.1016/J.Freeradbiomed.2012.10.548  0.498
2012 Park J, Piknova B, Nghiem K, Lozier JN, Schechter AN. Thrombelastographic Demonstration of Nitrite Inhibition of Platelet Function Blood. 120: 5148-5148. DOI: 10.1182/Blood.V120.21.5148.5148  0.336
2012 Akrawinthawong K, Piknova B, Sibmooh N, Fucharoen S, Schechter AN. Nitrite Inhibits Platelet Reactivity in Presence of Deoxygenated Red Blood Cells As Measured by Flow Cytometry Blood. 120: 5146-5146. DOI: 10.1182/Blood.V120.21.5146.5146  0.346
2011 Beleslin-ÄŒokić BB, Cokić VP, Wang L, Piknova B, Teng R, Schechter AN, Noguchi CT. Erythropoietin and hypoxia increase erythropoietin receptor and nitric oxide levels in lung microvascular endothelial cells. Cytokine. 54: 129-35. PMID 21324713 DOI: 10.1016/J.Cyto.2011.01.015  0.344
2011 Piknova B, Schechter AN. Measurement of nitrite in blood samples using the ferricyanide-based hemoglobin oxidation assay. Methods in Molecular Biology (Clifton, N.J.). 704: 39-56. PMID 21161628 DOI: 10.1007/978-1-61737-964-2_4  0.339
2011 Cokic VP, Markovic D, Mitrovic O, Vignjevic S, Djikic D, Beleslin-Cokic BB, Perunicic M, Ilic B, Jovcic G, Gotic M, Noguchi CT, Schechter AN. Angiogenic Factors eNOS and VEGF Have Increased Expression in Granulocytes of JAK2V617F Homozygous Forms of Polycythemia Vera Blood. 118: 3847-3847. DOI: 10.1182/Blood.V118.21.3847.3847  0.301
2010 Polzella BJ, Piknova B, Pluta R, Schechter AN. Nitric Oxide Metabolite Levels as a Function of Blood Oxygenation: An in vivo Animal Study Free Radical Biology and Medicine. 49. DOI: 10.1016/J.Freeradbiomed.2010.10.325  0.323
2009 Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, ... ... Schechter A, et al. Nitrate and nitrite in biology, nutrition and therapeutics. Nature Chemical Biology. 5: 865-9. PMID 19915529 DOI: 10.1038/Nchembio.260  0.473
2009 Cokić VP, Beleslin-Cokić BB, Smith RD, Economou AP, Wahl LM, Noguchi CT, Schechter AN. Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production. Experimental Hematology. 37: 1230-7. PMID 19576950 DOI: 10.1016/J.Exphem.2009.06.009  0.334
2009 Piknova B, Keszler A, Hogg N, Schechter AN. The reaction of cell-free oxyhemoglobin with nitrite under physiologically relevant conditions: Implications for nitrite-based therapies. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 20: 88-94. PMID 19010434 DOI: 10.1016/J.Niox.2008.10.005  0.316
2008 Schechter AN. Hemoglobin research and the origins of molecular medicine. Blood. 112: 3927-38. PMID 18988877 DOI: 10.1182/Blood-2008-04-078188  0.306
2008 Cokić VP, Schechter AN. Effects of nitric oxide on red blood cell development and phenotype. Current Topics in Developmental Biology. 82: 169-215. PMID 18282521 DOI: 10.1016/S0070-2153(07)00007-5  0.401
2008 Sibmooh N, Piknova B, Rizzatti F, Schechter AN. Oxidation of iron-nitrosyl-hemoglobin by dehydroascorbic acid releases nitric oxide to form nitrite in human erythrocytes. Biochemistry. 47: 2989-96. PMID 18225862 DOI: 10.1021/Bi702158D  0.314
2008 Cokic VP, Andric SA, Stojilkovic SS, Noguchi CT, Schechter AN. Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells. Blood. 111: 1117-23. PMID 17993617 DOI: 10.1182/Blood-2007-05-088732  0.341
2008 Chen K, Piknova B, Pittman RN, Schechter AN, Popel AS. Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 18: 47-60. PMID 17964300 DOI: 10.1016/J.Niox.2007.09.088  0.357
2007 Dejam A, Hunter CJ, Tremonti C, Pluta RM, Hon YY, Grimes G, Partovi K, Pelletier MM, Oldfield EH, Cannon RO, Schechter AN, Gladwin MT. Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation. Circulation. 116: 1821-31. PMID 17893272 DOI: 10.1161/Circulationaha.107.712133  0.441
2007 Cokic VP, Beleslin-Cokic BB, Noguchi CT, Schechter AN. Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 16: 371-8. PMID 17306993 DOI: 10.1016/J.Niox.2007.01.001  0.321
2007 Hsu LL, Champion HC, Campbell-Lee SA, Bivalacqua TJ, Manci EA, Diwan BA, Schimel DM, Cochard AE, Wang X, Schechter AN, Noguchi CT, Gladwin MT. Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability. Blood. 109: 3088-98. PMID 17158223 DOI: 10.1182/Blood-2006-08-039438  0.47
2007 Hsu LL, Shiva S, Noguchi A, Curtis E, MacArthur P, Raat NJH, Diwan BA, Schechter AN, Noguchi CT, Gladwin MT. Depletion and Restoration of the Intravascular Nitrite (NO2-) Reserve Modulate Susceptibility to Liver Vaso-Occlusive Infarction in Sickle Cell Transgenic Mice. Blood. 110: 841-841. DOI: 10.1182/Blood.V110.11.841.841  0.464
2007 Cokic VP, Beleslin-Cokic BB, Noguchi CT, Schechter AN. Globin Genes Induction by Nitric Oxide of Stromal Cell Origin. Blood. 110: 4102-4102. DOI: 10.1182/Blood.V110.11.4102.4102  0.336
2006 Pelletier MM, Kleinbongard P, Ringwood L, Hito R, Hunter CJ, Schechter AN, Gladwin MT, Dejam A. The measurement of blood and plasma nitrite by chemiluminescence: pitfalls and solutions. Free Radical Biology & Medicine. 41: 541-8. PMID 16863986 DOI: 10.1016/J.Freeradbiomed.2006.05.001  0.482
2006 Holly MK, Dear JW, Hu X, Schechter AN, Gladwin MT, Hewitt SM, Yuen PST, Star RA. Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure Kidney International. 70: 496-506. PMID 16760904 DOI: 10.1038/Sj.Ki.5001575  0.401
2006 Oneal PA, Gantt NM, Schwartz JD, Bhanu NV, Lee YT, Moroney JW, Reed CH, Schechter AN, Luban NL, Miller JL. Fetal hemoglobin silencing in humans. Blood. 108: 2081-6. PMID 16735596 DOI: 10.1182/Blood-2006-04-015859  0.303
2006 Cokic VP, Beleslin-Cokic BB, Tomic M, Stojilkovic SS, Noguchi CT, Schechter AN. Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells. Blood. 108: 184-91. PMID 16527893 DOI: 10.1182/Blood-2005-11-4454  0.332
2006 Kim-Shapiro DB, Schechter AN, Gladwin MT. Unraveling the reactions of nitric oxide, nitrite, and hemoglobin in physiology and therapeutics. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 697-705. PMID 16424350 DOI: 10.1161/01.Atv.0000204350.44226.9A  0.522
2006 Crawford JH, Isbell TS, Huang Z, Shiva S, Chacko BK, Schechter AN, Darley-Usmar VM, Kerby JD, Lang JD, Kraus D, Ho C, Gladwin MT, Patel RP. Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood. 107: 566-74. PMID 16195332 DOI: 10.1182/Blood-2005-07-2668  0.502
2006 Gladwin MT, Schechter AN, Kim-Shapiro DB, Patel RP, Hogg N, Shiva S, Cannon RO, Kelm M, Wink DA, Espey MG, Oldfield EH, Pluta RM, Freeman BA, Lancaster JR, Feelisch M, et al. Correction: Corrigendum: The emerging biology of the nitrite anion Nature Chemical Biology. 2: 110-110. DOI: 10.1038/Nchembio0206-110  0.42
2005 Gladwin MT, Schechter AN, Kim-Shapiro DB, Patel RP, Hogg N, Shiva S, Cannon RO, Kelm M, Wink DA, Espey MG, Oldfield EH, Pluta RM, Freeman BA, Lancaster JR, Feelisch M, et al. The emerging biology of the nitrite anion. Nature Chemical Biology. 1: 308-14. PMID 16408064 DOI: 10.1038/Nchembio1105-308  0.451
2005 Minneci PC, Deans KJ, Zhi H, Yuen PS, Star RA, Banks SM, Schechter AN, Natanson C, Gladwin MT, Solomon SB. Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin. The Journal of Clinical Investigation. 115: 3409-17. PMID 16294219 DOI: 10.1172/Jci25040  0.488
2005 Piknova B, Gladwin MT, Schechter AN, Hogg N. Electron paramagnetic resonance analysis of nitrosylhemoglobin in humans during NO inhalation. The Journal of Biological Chemistry. 280: 40583-8. PMID 16183646 DOI: 10.1074/Jbc.M506292200  0.466
2005 Huang Z, Shiva S, Kim-Shapiro DB, Patel RP, Ringwood LA, Irby CE, Huang KT, Ho C, Hogg N, Schechter AN, Gladwin MT. Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. The Journal of Clinical Investigation. 115: 2099-107. PMID 16041407 DOI: 10.1172/Jci24650  0.447
2005 Dejam A, Hunter CJ, Pelletier MM, Hsu LL, Machado RF, Shiva S, Power GG, Kelm M, Gladwin MT, Schechter AN. Erythrocytes are the major intravascular storage sites of nitrite in human blood. Blood. 106: 734-9. PMID 15774613 DOI: 10.1182/Blood-2005-02-0567  0.504
2005 d’Agostino C, Dejam A, Pelletier M, Sibmooh N, Rizzatti F, Schechter AN. Nitrite Ion Fluxes in Human Erythocytes. Blood. 106: 3731-3731. DOI: 10.1182/Blood.V106.11.3731.3731  0.34
2005 Cokic VP, Bhattacharya B, Puri RK, Schechter AN. Developmental and Differential Changes of Gene Expression in Erythroid Progenitor Cells. Blood. 106: 3648-3648. DOI: 10.1182/Blood.V106.11.3648.3648  0.305
2005 Hsu LL, Dejam A, Pelletier M, Cochard AE, Diwan B, Gladwin M, Schechter AN, Noguchi C. Sexual Dimorphism in Whole Blood Nitrite and Susceptibility to Hypoxic Sickle Cell Vaso-Occlusive Injury in Mice. Blood. 106: 2327-2327. DOI: 10.1182/Blood.V106.11.2327.2327  0.462
2005 Hsu LL, Champion HC, Manci E, Diwan B, Schimel D, Cochard A, Wang X, Holtzclaw JD, Schechter A, Noguchi CT, Gladwin M. Spontaneous Pulmonary Hypertension in Transgenic Sickle Cell Mice - Hemodynamics and Histology Suggest Abnormal Nitric Oxide Production and Scavenging. Blood. 106: 208-208. DOI: 10.1182/Blood.V106.11.208.208  0.45
2004 Hunter CJ, Dejam A, Blood AB, Shields H, Kim-Shapiro DB, Machado RF, Tarekegn S, Mulla N, Hopper AO, Schechter AN, Power GG, Gladwin MT. Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator. Nature Medicine. 10: 1122-7. PMID 15361865 DOI: 10.1038/Nm1109  0.452
2004 Stroncek DF, Byrne KM, Noguchi CT, Schechter AN, Leitman SF. Increasing hemoglobin oxygen saturation levels in sickle trait donor whole blood prevents hemoglobin S polymerization and allows effective white blood cell reduction by filtration. Transfusion. 44: 1293-9. PMID 15318851 DOI: 10.1111/J.0041-1132.2004.04086.X  0.334
2004 Kim-Shapiro DB, Patel RP, Schechter AN, Gladwin MT, Cannon RO, Hogg N. How do red blood cells dilate blood vessels?--Reply. Circulation Research. 95: e10. PMID 15297387 DOI: 10.1161/Res.95.3.E10  0.499
2004 Beleslin-Cokic BB, Cokic VP, Yu X, Weksler BB, Schechter AN, Noguchi CT. Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells. Blood. 104: 2073-80. PMID 15205261 DOI: 10.1182/Blood-2004-02-0744  0.365
2004 Dejam A, Hunter CJ, Schechter AN, Gladwin MT. Emerging role of nitrite in human biology. Blood Cells, Molecules & Diseases. 32: 423-9. PMID 15121102 DOI: 10.1016/J.Bcmd.2004.02.002  0.485
2004 Gladwin MT, Schechter AN. NO contest: nitrite versus S-nitroso-hemoglobin. Circulation Research. 94: 851-5. PMID 15087423 DOI: 10.1161/01.Res.0000126697.64381.37  0.513
2004 Gladwin MT, Sachdev V, Jison ML, Shizukuda Y, Plehn JF, Minter K, Brown B, Coles WA, Nichols JS, Ernst I, Hunter LA, Blackwelder WC, Schechter AN, Rodgers GP, Castro O, et al. Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. The New England Journal of Medicine. 350: 886-95. PMID 14985486 DOI: 10.1056/Nejmoa035477  0.432
2004 Oneal PA, Schwartz JD, Gantt N, Bhanu N, Lee YT, Gherman R, Schechter AN, Luban NLC, Miller J. Two Cellular Mechanisms for Gamma-Globin Gene and Protein Silencing in Humans. Blood. 104: 374-374. DOI: 10.1182/Blood.V104.11.374.374  0.307
2004 Hsu LL, Gladwin M, Cui XZ, Li Y, Schechter AN, Noguchi CT, Schimel D, Diwan B, Manci EA, Eichacker PQ. Mouse Pneumonia Model of Sickle Cell Acute Chest Syndrome. Blood. 104: 3582-3582. DOI: 10.1182/Blood.V104.11.3582.3582  0.427
2004 Dejam A, Gladwin MT, Christian HCJ, Hsu L, Grear JJ, Tarekegn S, Shruti S, Kelm M, Schechter AN. Characterization of the Distribution of Nitrite in Human Blood. Blood. 104: 238-238. DOI: 10.1182/Blood.V104.11.238.238  0.48
2003 Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, Yang BK, Waclawiw MA, Zalos G, Xu X, Huang KT, Shields H, Kim-Shapiro DB, Schechter AN, Cannon RO, et al. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nature Medicine. 9: 1498-505. PMID 14595407 DOI: 10.1038/Nm954  0.5
2003 Haley JD, Smith DE, Schwedes J, Brennan R, Pearce C, Moore C, Wang F, Petti F, Grosveld F, Jane SM, Noguchi CT, Schechter AN. Identification and characterization of mechanistically distinct inducers of gamma-globin transcription. Biochemical Pharmacology. 66: 1755-68. PMID 14563486 DOI: 10.1016/S0006-2952(03)00542-2  0.313
2003 Gladwin MT, Lancaster JR, Freeman BA, Schechter AN. Nitric oxide's reactions with hemoglobin: a view through the SNO-storm. Nature Medicine. 9: 496-500. PMID 12724752 DOI: 10.1038/Nm0503-496  0.498
2003 Schechter AN, Gladwin MT. Hemoglobin and the paracrine and endocrine functions of nitric oxide. The New England Journal of Medicine. 348: 1483-5. PMID 12686706 DOI: 10.1056/Nejmcibr023045  0.465
2003 Zborowski M, Ostera GR, Moore LR, Milliron S, Chalmers JJ, Schechter AN. Red blood cell magnetophoresis. Biophysical Journal. 84: 2638-45. PMID 12668472 DOI: 10.1016/S0006-3495(03)75069-3  0.753
2003 Smith RD, Brown B, Ikonomi P, Schechter AN. Exogenous reference RNA for normalization of real-time quantitative PCR. Biotechniques. 34: 88-91. PMID 12545545 DOI: 10.2144/03341St05  0.303
2003 Gladwin MT, Schechter AN, Ognibene FP, Coles WA, Reiter CD, Schenke WH, Csako G, Waclawiw MA, Panza JA, Cannon RO. Divergent nitric oxide bioavailability in men and women with sickle cell disease. Circulation. 107: 271-8. PMID 12538427 DOI: 10.1161/01.Cir.0000044943.12533.A8  0.465
2003 Cokic VP, Smith RD, Beleslin-Cokic BB, Njoroge JM, Miller JL, Gladwin MT, Schechter AN. Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase. The Journal of Clinical Investigation. 111: 231-9. PMID 12531879 DOI: 10.1172/Jci16672  0.517
2003 Noguchi CT, Schechter AN, Haley JD, Abraham DJ. Inhibition of Sickle Hemoglobin Polymerization as a Basis for Therapeutic Approaches to Sickle‐Cell Anemia Burger's Medicinal Chemistry and Drug Discovery. 443-477. DOI: 10.1002/0471266949.Bmc050  0.327
2002 Reiter CD, Wang X, Tanus-Santos JE, Hogg N, Cannon RO, Schechter AN, Gladwin MT. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nature Medicine. 8: 1383-9. PMID 12426562 DOI: 10.1038/Nm799  0.494
2002 Stroncek DF, Rainer T, Sharon V, Byrne KM, Noguchi CT, Klein HG, Schechter AN, Leitman SF. Sickle Hb polymerization in RBC components from donors with sickle cell trait prevents effective WBC reduction by filtration. Transfusion. 42: 1466-72. PMID 12421220 DOI: 10.1046/J.1537-2995.2002.00206.X  0.316
2002 Xu X, Lockamy VL, Chen K, Huang Z, Shields H, King SB, Ballas SK, Nichols JS, Gladwin MT, Noguchi CT, Schechter AN, Kim-Shapiro DB. Effects of iron nitrosylation on sickle cell hemoglobin solubility. The Journal of Biological Chemistry. 277: 36787-92. PMID 12138112 DOI: 10.1074/Jbc.M205350200  0.492
2002 Gladwin MT, Wang X, Reiter CD, Yang BK, Vivas EX, Bonaventura C, Schechter AN. S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function. The Journal of Biological Chemistry. 277: 27818-28. PMID 12023289 DOI: 10.1074/Jbc.M203236200  0.499
2002 Gladwin MT, Shelhamer JH, Ognibene FP, Pease-Fye ME, Nichols JS, Link B, Patel DB, Jankowski MA, Pannell LK, Schechter AN, Rodgers GP. Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease. British Journal of Haematology. 116: 436-44. PMID 11841449 DOI: 10.1046/J.1365-2141.2002.03274.X  0.504
2001 Noguchi CT, Gladwin M, Diwan B, Merciris P, Smith R, Yu X, Buzard G, Fitzhugh A, Keefer LK, Schechter AN, Mohandas N. Pathophysiology of a sickle cell trait mouse model: Human αβS transgenes with one mouse β-globin allele Blood Cells, Molecules, and Diseases. 27: 971-977. PMID 11831863 DOI: 10.1006/Bcmd.2001.0469  0.457
2001 Gladwin MT, Ognibene FP, Shelhamer JH, Pease-Fye ME, Noguchi CT, Rodgers GP, Schechter AN. Nitric oxide transport on sickle cell hemoglobin: Where does it bind? Free Radical Research. 35: 175-180. PMID 11697198 DOI: 10.1080/10715760100300721  0.522
2001 Gladwin MT, Schechter AN. Nitric oxide therapy in sickle cell disease Seminars in Hematology. 38: 333-342. PMID 11605168 DOI: 10.1016/S0037-1963(01)90027-7  0.509
2001 Cannon RO, Schechter AN, Panza JA, Ognibene FP, Pease-Fye ME, Waclawiw MA, Shelhamer JH, Gladwin MT. Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery Journal of Clinical Investigation. 108: 279-287. PMID 11457881 DOI: 10.1172/Jci12761  0.485
2000 Ikonomi P, Rivera CE, Riordan M, Washington G, Schechter AN, Noguchi CT. Overexpression of GATA-2 inhibits erythroid and promotes megakaryocyte differentiation. Experimental Hematology. 28: 1423-31. PMID 11146164 DOI: 10.1016/S0301-472X(00)00553-1  0.322
2000 Smith RD, Malley JD, Schechter AN. Quantitative analysis of globin gene induction in single human erythroleukemic cells Nucleic Acids Research. 28: 4998-5004. PMID 11121491 DOI: 10.1093/Nar/28.24.4998  0.332
2000 Gladwin MT, Shelhamer JH, Schechter AN, Pease-Fye ME, Waclawiw MA, Panza JA, Ognibene FP, Cannon RO. Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans Proceedings of the National Academy of Sciences of the United States of America. 97: 11482-11487. PMID 11027349 DOI: 10.1073/Pnas.97.21.11482  0.489
2000 Hrinczenko BW, Schechter AN, Wojtkowski TL, Pannell LK, Cashon RE, Alayash AI. Nitric oxide-mediated heme oxidation and selective β-globin nitrosation of hemoglobin from normal and sickle erythrocytes Biochemical and Biophysical Research Communications. 275: 962-967. PMID 10973828 DOI: 10.1006/Bbrc.2000.3413  0.351
2000 Hrinczenko BW, Alayash AI, Wink DA, Gladwin MT, Rodgers GP, Schechter AN. Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport British Journal of Haematology. 110: 412-419. PMID 10971400 DOI: 10.1046/J.1365-2141.2000.02203.X  0.521
2000 Gladwin MT, Ognibene FP, Pannell LK, Nichols JS, Pease-Fye ME, Shelhamer JH, Schechter AN. Relative role of heme nitrosylation and beta-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation. Proceedings of the National Academy of Sciences of the United States of America. 97: 9943-8. PMID 10954746 DOI: 10.1073/Pnas.180155397  0.479
2000 Schechter AN, Rodgers GP, Strasser BJ. Sickle cell anemia therapy: Progress since Pauling [3] (multiple letters) Science. 287: 592-593. PMID 10691539 DOI: 10.1126/Science.287.5453.591D  0.318
1999 Gladwin MT, Schechter AN, Shelhamer JH, Pannell LK, Conway DA, Hrinczenko BW, Nichols JS, Pease-Fye ME, Noguchi CT, Rodgers GP, Ognibene FP. Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity. The Journal of Clinical Investigation. 104: 937-45. PMID 10510334 DOI: 10.1172/Jci7637  0.515
1999 Gladwin MT, Schechter AN, Shelhamer JH, Ognibene FP. The acute chest syndrome in sickle cell disease: Possible role of nitric oxide in its pathophysiology and treatment American Journal of Respiratory and Critical Care Medicine. 159: 1368-1376. PMID 10228097 DOI: 10.1164/Ajrccm.159.5.9810094  0.457
1996 Oonishi T, Sakashita K, Suematsu N, Schechter AN, Uyesaka N. Quantitative characterization of P-glycoprotein-mediated transport in mdr1-gene-transfected lymphoma cells Japanese Journal of Physiology. 46: 33-41. PMID 8743716 DOI: 10.2170/Jjphysiol.46.33  0.305
1995 Hiruma H, Noguchi CT, Uyesaka N, Hasegawa S, Blanchette-Mackie EJ, Schechter AN, Rodgers GP. Sickle cell rheology is determined by polymer fraction - not cell morphology American Journal of Hematology. 48: 19-28. PMID 7832188 DOI: 10.1002/Ajh.2830480105  0.328
1995 Hiruma H, Noguchi CT, Uyesaka N, Schechter AN, Rodgers GP. Contributions of sickle hemoglobin polymer and sickle cell membranes to impaired filterability American Journal of Physiology - Heart and Circulatory Physiology. 268. PMID 7771550 DOI: 10.1152/Ajpheart.1995.268.5.H2003  0.309
1995 Hasegawa S, Hiruma H, Uyesaka N, Noguchi CT, Schechter AN, Rodgers GP. Filterability of mixtures of sickle and normal erythrocytes American Journal of Hematology. 50: 91-97. PMID 7573006 DOI: 10.1002/Ajh.2830500204  0.321
1995 Fibach E, Kollia P, Schechter AN, Noguchi CT, Rodgers GP. Hemin-induced acceleration of hemoglobin production in immature cultured erythroid cells: Preferential enhancement of fetal hemoglobin Blood. 85: 2967-2974. PMID 7537986 DOI: 10.1182/Blood.V85.10.2967.Bloodjournal85102967  0.332
1994 Fibach E, Schechter AN, Noguchi CT, Rodgers GP. Reducing erythropoietin in cultures of human erythroid precursors elevates the proportion of fetal haemoglobin British Journal of Haematology. 88: 39-45. PMID 7528530 DOI: 10.1111/J.1365-2141.1994.Tb04974.X  0.33
1994 Uyesaka N, Hasegawa S, Nakamura T, Hongo AT, Stuart J, Schechter AN, Shio H. Pathophysiologic significance of mechanical fragility of red blood cells Clinical Hemorheology and Microcirculation. 14: 557-570. DOI: 10.3233/Ch-1994-14411  0.337
1993 Noguchi CT, Schechter AN, Rodgers GP. 3 Sickle cell disease pathophysiology Bailliere's Clinical Haematology. 6: 57-91. PMID 8353318 DOI: 10.1016/S0950-3536(05)80066-6  0.336
1993 Fibach E, Burke LP, Schechter AN, Noguchi CT, Rodgers GP. Hydroxyurea increases fetal hemoglobin in cultured erythroid cells derived from normal individuals and patients with sickle cell anemia or β-thalassemia Blood. 81: 1630-1635. PMID 7680923 DOI: 10.1182/Blood.V81.6.1630.1630  0.341
1993 Rodgers GP, Dover GJ, Uyesaka N, Noguchi CT, Schechter AN, Nienhuis AW. Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease. The New England Journal of Medicine. 328: 73-80. PMID 7677965 DOI: 10.1056/Nejm199301143280201  0.323
1992 Gutman PD, Cao SX, Dave HP, Mittelman M, Schechter AN. Binding of erythroid and non-erythroid nuclear proteins to the silencer of the human epsilon-globin-encoding gene. Gene. 110: 197-203. PMID 1537556 DOI: 10.1016/0378-1119(92)90648-9  0.313
1990 Rodgers GP, Schechter AN, Noguchi CT, Klein HG, Nienhuis AW, Bonner RF. Microcirculatory adaptations in sickle cell anemia: Reactive hyperemia response American Journal of Physiology - Heart and Circulatory Physiology. 258: H113-H120. PMID 2405712 DOI: 10.1152/Ajpheart.1990.258.1.H113  0.305
1990 Rodgers GP, Dover GJ, Noguchi CT, Schechter AN, Nienhuis AW. Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea New England Journal of Medicine. 322: 1037-1045. PMID 1690857 DOI: 10.1056/Nejm199004123221504  0.306
1989 NOGUCHI CT, RODGERS GP, SCHECHTER AN. Intracellular Polymerization: Disease Severity and Therapeutic Predictions Annals of the New York Academy of Sciences. 565: 75-82. PMID 2476066 DOI: 10.1111/J.1749-6632.1989.Tb24152.X  0.303
1988 Rodgers GP, Roy MS, Noguchi CT, Schechter AN. Is there a role for selective vasodilation in the management of sickle cell disease? Blood. 71: 597-602. PMID 3345339 DOI: 10.1182/Blood.V71.3.597.Bloodjournal713597  0.314
1988 Rodgers GP, Roy MS, Noguchi CT, Schechter AN. Use of selective vasodilation in treatment of sickle cell disease. The American Journal of Pediatric Hematology/Oncology. 10: 351-6. PMID 3071169 DOI: 10.1097/00043426-198824000-00018  0.334
1987 Acquaye C, Walker EC, Schechter AN. The development of a filtration system for evaluating flow characteristics of erythrocytes Microvascular Research. 33: 1-14. PMID 3561261 DOI: 10.1016/0026-2862(87)90002-1  0.325
1986 Fordis CM, Nelson N, McCormick M, Padmanabhan R, Howard B, Schechter AN. The 5'-flanking sequences of human globin genes contribute to tissue specific expression. Biochemical and Biophysical Research Communications. 134: 128-33. PMID 3456225 DOI: 10.1016/0006-291X(86)90536-X  0.301
1985 Rodgers GP, Noguchi CT, Schechter AN. Irreversibly sickled erythrocytes in sickle cell anemia: A quantitative reappraisal American Journal of Hematology. 20: 17-23. PMID 4025318 DOI: 10.1002/Ajh.2830200104  0.359
1985 Roy MS, Rodgers GP, Podgor MJ, Noguchi CT, Nienhuis AW, Schechter AN. Conjunctival sign in sickle cell anaemia: An in-vivo correlate of the extent of red cell heterogeneity British Journal of Ophthalmology. 69: 629-632. PMID 4016063 DOI: 10.1136/Bjo.69.8.629  0.317
1985 Noguchi CT, Dover GJ, Rodgers GP, Serjeant GR, Antonarakis SE, Anagnou NP, Higgs DR, Weatherall DJ, Schechter AN. Alpha thalassemia changes erythrocyte heterogeneity in sickle cell disease Journal of Clinical Investigation. 75: 1632-1637. PMID 2581999 DOI: 10.1172/Jci111870  0.3
1984 Fordis CM, Anagnou NP, Dean A, Nienhuis AW, Schechter AN. A beta-globin gene, inactive in the K562 leukemic cell, functions normally in a heterologous expression system Proceedings of the National Academy of Sciences of the United States of America. 81: 4485-4489. PMID 6205398 DOI: 10.1073/Pnas.81.14.4485  0.599
1984 Wu Y, Dean A, Egan W, Schechter AN. Control of oxygen affinity of hemoglobin in K562 cells induced by hemin. Blood. 63: 1447-1452. DOI: 10.1182/Blood.V63.6.1447.1447  0.65
1983 Dean A, Ley TJ, Humphries RK, Fordis M, Schechter AN. Inducible transcription of five globin genes in K562 human leukemia cells Proceedings of the National Academy of Sciences of the United States of America. 80: 5515-5519. PMID 6310580 DOI: 10.1073/Pnas.80.18.5515  0.624
1983 Ley T, DeSimone J, Noguchi C, Turner P, Schechter A, Heller P, Nienhuis A. 5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia Blood. 62: 370-380. DOI: 10.1182/Blood.V62.2.370.Bloodjournal622370  0.319
1983 Klausner RD, Van Renswoude J, Ashwell G, Kempf C, Schechter AN, Dean A, Bridges KR. Receptor-mediated endocytosis of transferrin in K562 cells. Journal of Biological Chemistry. 258: 4715-4724. DOI: 10.1016/s0021-9258(18)32481-5  0.555
1982 Bunn HF, Noguchi CT, Hofrichter J, Schechter GP, Schechter AN, Eaton WA. Molecular and cellular pathogenesis of hemoglobin SC disease. Proceedings of the National Academy of Sciences of the United States of America. 79: 7527-31. PMID 6961429 DOI: 10.1073/Pnas.79.23.7527  0.32
1981 Dean A, Erard F, Schneider AB, Schechter AN. Induction of hemoglobin accumulation in human K562 cells by hemin is reversible Science. 212: 459-461. PMID 6163216 DOI: 10.1126/Science.6163216  0.631
1981 Erard F, Dean A, Schechter A. Inhibitors of cell division reversibly modify hemoglobin concentration in human erythroleukemia K562 cells Blood. 58: 1236-1239. DOI: 10.1182/Blood.V58.6.1236.Bloodjournal5861236  0.643
1981 Dean A, Schechter A, Papayannopoulou T, Stamatoyannopoulos G. Heterogeneity of erythroid precursor cells. Hemoglobin quantitation in single clones by radioimmunoassay. Journal of Biological Chemistry. 256: 2447-2453. DOI: 10.1016/s0021-9258(19)69801-7  0.588
1980 Alston K, Dean A, Schechter AN. The immunochemical effects of metal substitution in the prosthetic group of hemoglobin. Molecular Immunology. 17: 1475-85. PMID 6170875 DOI: 10.1016/0161-5890(80)90173-X  0.582
1975 Furie B, Schechter AN, Sachs DH, Anfinsen CB. An immunological approach to the conformational equilibrium of staphylococcal nuclease. Journal of Molecular Biology. 92: 497-506. PMID 1171246 DOI: 10.1016/0022-2836(75)90305-8  0.515
1975 Young NS, Curd JG, Eastlake A, Furie B, Schechter AN. Isolation of antibodies specific to sickle hemoglobin by affinity chromatography using a synthetic peptide Proceedings of the National Academy of Sciences of the United States of America. 72: 4759-4763. PMID 813215 DOI: 10.1073/Pnas.72.12.4759  0.508
1974 Furie B, Griffin JH, Feldmann RJ, Sokoloski EA, Schechter AN. The active site of staphylococcal nuclease: paramagnetic relaxation of bound nucleotide inhibitor nuclei by lanthanide ions. Proceedings of the National Academy of Sciences of the United States of America. 71: 2833-7. PMID 4528015 DOI: 10.1073/Pnas.71.7.2833  0.487
1974 Furie B, Schechter AN, Sachs DH, Anfinsen CB. Antibodies to the unfolded form of a helix-rich region in staphylococcal nuclease. Biochemistry. 13: 1561-6. PMID 4364704 DOI: 10.1021/Bi00705A001  0.607
1974 Eastlake A, Sachs DH, Schechter AN, Anfinsen CB. Binding of univalent antibody fragments to a distinct antigenic determinant of staphylococcal nuclease. Biochemistry. 13: 1567-71. PMID 4133940 DOI: 10.1021/Bi00705A002  0.494
1973 Furie B, Eastlake A, Schechter AN, Anfinsen CB. The interaction of the lanthanide ions with staphylococcal nuclease. The Journal of Biological Chemistry. 248: 2821-5. PMID 4723899  0.408
1973 Anfinsen C, Goldberger R, Schechter A. Current topics in Biochemistry. National institutes of health lectures in biomedical sciences Food and Cosmetics Toxicology. 11: 1116-1117. DOI: 10.1016/0015-6264(73)90268-X  0.469
1972 Anfinsen CB, Schechter AN, Taniuchi H. Some aspects of the structure of Staphylococcal nuclease. II. Studies in solution. Cold Spring Harbor Symposia On Quantitative Biology. 36: 249-55. PMID 4343717  0.423
1972 Sachs DH, Schechter AN, Eastlake A, Anfinsen CB. An immunologic approach to the conformational equilibria of polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 69: 3790-4. PMID 4118873 DOI: 10.1073/Pnas.69.12.3790  0.516
1972 Sachs DH, Schechter AN, Eastlake A, Anfinsen CB. Inactivation of staphylococcal nuclease by the binding of antibodies to a distinct antigenic determinant. Biochemistry. 11: 4268-73. PMID 4116930 DOI: 10.1021/Bi00773A012  0.495
1972 Anfinsen CB, Schechter AN, Taniuchi H. Some Aspects of the Structure of Staphylococcal Nuclease PART II. STUDIES IN SOLUTION Cold Spring Harbor Symposia On Quantitative Biology. 36: 243-255. DOI: 10.1101/Sqb.1972.036.01.033  0.482
1971 Epstein HF, Schechter AN, Chen RF, Anfinsen CB. Folding of staphylococcal nuclease: kinetic studies of two processes in acid renaturation. Journal of Molecular Biology. 60: 499-508. PMID 5110314 DOI: 10.1016/0022-2836(71)90184-7  0.507
1970 Schechter AN, Chen RF, Anfinsen CB. Kinetics of folding of staphylococcal nuclease. Science (New York, N.Y.). 167: 886-7. PMID 5410853 DOI: 10.1126/Science.167.3919.886  0.503
1969 Schechter AN, Morávek L, Anfinsen CB. Hydrogen exchange in proteins as a measure of solvent exclusion due to ligands. Nuclease and myoglobin. The Journal of Biological Chemistry. 244: 4981-8. PMID 5824573  0.423
1968 Schechter AN, Morávek L, Anfinsen CB. Suppression of hydrogen exchange in staphylococcal nuclease by ligands. Proceedings of the National Academy of Sciences of the United States of America. 61: 1478-85. PMID 5249820 DOI: 10.1073/Pnas.61.4.1478  0.501
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