Leo LeFrancois - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Microbiology Biology, Immunology

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Imperato JN, Xu D, Romagnoli PA, Qiu Z, Perez P, Khairallah C, Pham QM, Andrusaite A, Bravo-Blas A, Milling SWF, Lefrancois L, Khanna KM, Puddington L, Sheridan BS. Mucosal CD8 T Cell Responses Are Shaped by Batf3-DC After Foodborne Infection. Frontiers in Immunology. 11: 575967. PMID 33042159 DOI: 10.3389/fimmu.2020.575967  0.821
2020 Imperato JN, Xu D, Romagnoli PA, Qiu Z, Perez P, Khairallah C, Pham Q, Andrusaite A, Bravo-Blas A, Milling SWF, Lefrancois L, Khanna KM, Puddington L, Sheridan BS. Mucosal CD8 T Cell Responses Are Shaped by Batf3-DC After Foodborne Listeria monocytogenes Infection Frontiers in Immunology. 11. DOI: 10.3389/Fimmu.2020.575967  0.843
2016 Romagnoli PA, Fu HH, Qiu Z, Khairallah C, Pham QM, Puddington L, Khanna KM, Lefrançois L, Sheridan BS. Differentiation of distinct long-lived memory CD4 T cells in intestinal tissues after oral Listeria monocytogenes infection. Mucosal Immunology. PMID 27461178 DOI: 10.1038/Mi.2016.66  0.862
2016 Romagnoli PA, Sheridan BS, Pham QM, Lefrançois L, Khanna KM. IL-17A-producing resident memory γδ T cells orchestrate the innate immune response to secondary oral Listeria monocytogenes infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 27402748 DOI: 10.1073/Pnas.1600713113  0.842
2015 Sharma N, Benechet AP, Lefrançois L, Khanna KM. CD8 T Cells Enter the Splenic T Cell Zones Independently of CCR7, but the Subsequent Expansion and Trafficking Patterns of Effector T Cells after Infection Are Dysregulated in the Absence of CCR7 Migratory Cues. Journal of Immunology (Baltimore, Md. : 1950). PMID 26500349 DOI: 10.4049/Jimmunol.1500993  0.873
2015 Colpitts SL, Puddington L, Lefrançois L. IL-15 receptor α signaling constrains the development of IL-17-producing γδ T cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 9692-7. PMID 26195801 DOI: 10.1073/Pnas.1420741112  0.816
2015 Plumlee CR, Obar JJ, Colpitts SL, Jellison ER, Haining WN, Lefrancois L, Khanna KM. Early Effector CD8 T Cells Display Plasticity in Populating the Short-Lived Effector and Memory-Precursor Pools Following Bacterial or Viral Infection. Scientific Reports. 5: 12264. PMID 26191658 DOI: 10.1038/Srep12264  0.833
2015 Cheroutre H, Lefrancois L. Intraepithelial TCRαβ T Cells in Health and Disease Mucosal Immunology: Fourth Edition. 1: 733-748. DOI: 10.1016/B978-0-12-415847-4.00035-5  0.45
2014 Bose TO, Colpitts SL, Pham QM, Puddington L, Lefrançois L. CD11a is essential for normal development of hematopoietic intermediates. Journal of Immunology (Baltimore, Md. : 1950). 193: 2863-72. PMID 25108025 DOI: 10.4049/Jimmunol.1301820  0.824
2014 Sheridan BS, Pham QM, Lee YT, Cauley LS, Puddington L, Lefrançois L. Oral infection drives a distinct population of intestinal resident memory CD8(+) T cells with enhanced protective function. Immunity. 40: 747-57. PMID 24792910 DOI: 10.1016/J.Immuni.2014.03.007  0.817
2014 Masopust D, Vezys V, Marzo AL, Lefrançois L. Pillars article: preferential localization of effector memory cells in nonlymphoid tissue. Science. 2001. 291: 2413-2417. Journal of Immunology (Baltimore, Md. : 1950). 192: 845-9. PMID 24443507 DOI: 10.1126/Science.1058867  0.852
2013 Colpitts SL, Stonier SW, Stoklasek TA, Root SH, Aguila HL, Schluns KS, Lefrançois L. Transcriptional regulation of IL-15 expression during hematopoiesis. Journal of Immunology (Baltimore, Md. : 1950). 191: 3017-24. PMID 23966624 DOI: 10.4049/Jimmunol.1301389  0.805
2013 Plumlee CR, Sheridan BS, Cicek BB, Lefrançois L. Environmental cues dictate the fate of individual CD8+ T cells responding to infection. Immunity. 39: 347-56. PMID 23932571 DOI: 10.1016/J.Immuni.2013.07.014  0.874
2013 Sheridan B, Romagnoli P, Pham QM, Fu HH, Alonzo F, Schubert WD, Freitag N, Lefrançois L. γδ T Cells Exhibit Multifunctional and Protective Memory in Intestinal Tissues Immunity. 39: 184-195. PMID 23890071 DOI: 10.1016/J.Immuni.2013.06.015  0.859
2013 Bose TO, Pham QM, Jellison ER, Mouries J, Ballantyne CM, Lefrançois L. CD11a regulates effector CD8 T cell differentiation and central memory development in response to infection with Listeria monocytogenes. Infection and Immunity. 81: 1140-51. PMID 23357382 DOI: 10.1128/Iai.00749-12  0.823
2013 Kumar S, Colpitts SL, Ménoret A, Budelsky AL, Lefrancois L, Vella AT. Rapid αβ T-cell responses orchestrate innate immunity in response to Staphylococcal enterotoxin A Mucosal Immunology. 6: 1006-1015. PMID 23321986 DOI: 10.1038/Mi.2012.138  0.542
2012 Jellison ER, Turner MJ, Blair DA, Lingenheld EG, Zu L, Puddington L, Lefrançois L. Distinct mechanisms mediate naive and memory CD8 T-cell tolerance. Proceedings of the National Academy of Sciences of the United States of America. 109: 21438-43. PMID 23236165 DOI: 10.1073/Pnas.1217409110  0.863
2012 Cauley LS, Lefrançois L. Guarding the perimeter: protection of the mucosa by tissue-resident memory T cells. Mucosal Immunology. 6: 14-23. PMID 23131785 DOI: 10.1038/Mi.2012.96  0.523
2012 Sheridan BS, Lefrançois L. Isolation of mouse lymphocytes from small intestine tissues. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit3.19. PMID 23129154 DOI: 10.1002/0471142735.Im0319S99  0.7
2012 Anderson KG, Sung H, Skon CN, Lefrancois L, Deisinger A, Vezys V, Masopust D. Cutting edge: intravascular staining redefines lung CD8 T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 189: 2702-6. PMID 22896631 DOI: 10.4049/Jimmunol.1201682  0.851
2012 Khanna KM, Lefrançois L. B cells, not just for antibody anymore. Immunity. 36: 315-7. PMID 22444627 DOI: 10.1016/J.Immuni.2012.02.011  0.676
2012 Colpitts SL, Stoklasek TA, Plumlee CR, Obar JJ, Guo C, Lefrançois L. Cutting edge: The role of IFN-α receptor and MyD88 signaling in induction of IL-15 expression in vivo Journal of Immunology. 188: 2483-2487. PMID 22327071 DOI: 10.4049/Jimmunol.1103609  0.79
2011 Khanna KM, Lefrançois L. Imaging-and Imagining-Immune Responses to Infections: Laser-scanning confocal microscopy pinpoints responses of immune system components to bacterial infections in situ. Microbe (Washington, D.C.). 6: 63-68. PMID 23226990 DOI: 10.1128/Microbe.6.63.1  0.663
2011 Teijaro JR, Turner D, Pham Q, Wherry EJ, Lefrançois L, Farber DL. Cutting edge: Tissue-retentive lung memory CD4 T cells mediate optimal protection to respiratory virus infection. Journal of Immunology (Baltimore, Md. : 1950). 187: 5510-4. PMID 22058417 DOI: 10.4049/Jimmunol.1102243  0.719
2011 Obar JJ, Jellison ER, Sheridan BS, Blair DA, Pham QM, Zickovich JM, Lefrançois L. Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 187: 4967-78. PMID 21987662 DOI: 10.4049/Jimmunol.1102335  0.869
2011 Sheridan BS, Lefrançois L. Regional and mucosal memory T cells. Nature Immunology. 12: 485-91. PMID 21739671 DOI: 10.1038/Ni.2029  0.764
2010 Stoklasek TA, Colpitts SL, Smilowitz HM, Lefrançois L. MHC class I and TCR avidity control the CD8 T cell response to IL-15/IL-15Rα complex. Journal of Immunology (Baltimore, Md. : 1950). 185: 6857-65. PMID 21041729 DOI: 10.4049/Jimmunol.1001601  0.814
2010 Sheridan BS, Lefrançois L. Intraepithelial lymphocytes: to serve and protect. Current Gastroenterology Reports. 12: 513-21. PMID 20890736 DOI: 10.1007/S11894-010-0148-6  0.661
2010 Thangada S, Khanna KM, Blaho VA, Oo ML, Im DS, Guo C, Lefrancois L, Hla T. Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics. The Journal of Experimental Medicine. 207: 1475-83. PMID 20584883 DOI: 10.1084/Jem.20091343  0.676
2010 Lefrançois L, Obar JJ. Once a killer, always a killer: from cytotoxic T cell to memory cell. Immunological Reviews. 235: 206-18. PMID 20536565 DOI: 10.1111/J.0105-2896.2010.00895.X  0.791
2010 Khanna KM, Blair DA, Vella AT, McSorley SJ, Datta SK, Lefrançois L. T cell and APC dynamics in situ control the outcome of vaccination. Journal of Immunology (Baltimore, Md. : 1950). 185: 239-52. PMID 20530268 DOI: 10.4049/Jimmunol.0901047  0.829
2010 Obar JJ, Lefrançois L. Early signals during CD8 T cell priming regulate the generation of central memory cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 263-72. PMID 20519649 DOI: 10.4049/Jimmunol.1000492  0.842
2010 Obar JJ, Lefrançois L. Early events governing memory CD8+ T-cell differentiation. International Immunology. 22: 619-25. PMID 20504887 DOI: 10.1093/Intimm/Dxq053  0.827
2010 Zehn D, Turner MJ, Lefrançois L, Bevan MJ. Lack of original antigenic sin in recall CD8(+) T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 184: 6320-6. PMID 20439913 DOI: 10.4049/Jimmunol.1000149  0.746
2010 Obar JJ, Lefrançois L. Memory CD8+ T cell differentiation. Annals of the New York Academy of Sciences. 1183: 251-66. PMID 20146720 DOI: 10.1111/J.1749-6632.2009.05126.X  0.833
2010 Obar JJ, Molloy MJ, Jellison ER, Stoklasek TA, Zhang W, Usherwood EJ, Lefrançois L. CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses. Proceedings of the National Academy of Sciences of the United States of America. 107: 193-8. PMID 19966302 DOI: 10.1073/Pnas.0909945107  0.854
2010 Colpitts SL, Stokalsek TA, Joshua JO, Guo C, Lefrançois L. SS11-3 Interleukin-15 expression in dendritic cell and T cell subsets revealed using a novel reporter system Cytokine. 52: 80-80. DOI: 10.1016/J.Cyto.2010.07.334  0.533
2009 Lefrançois L, Masopust D. The road not taken: memory T cell fate 'decisions'. Nature Immunology. 10: 369-70. PMID 19295636 DOI: 10.1038/Ni0409-369  0.734
2008 Khanna KM, Aguila CC, Redman JM, Suarez-Ramirez JE, Lefrançois L, Cauley LS. In situ imaging reveals different responses by naïve and memory CD8 T cells to late antigen presentation by lymph node DC after influenza virus infection. European Journal of Immunology. 38: 3304-15. PMID 19009527 DOI: 10.1002/Eji.200838602  0.788
2008 Turner MJ, Jellison ER, Lingenheld EG, Puddington L, Lefrançois L. Avidity maturation of memory CD8 T cells is limited by self-antigen expression. The Journal of Experimental Medicine. 205: 1859-68. PMID 18625745 DOI: 10.1084/Jem.20072390  0.808
2008 Obar JJ, Khanna KM, Lefrançois L. Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. Immunity. 28: 859-69. PMID 18499487 DOI: 10.1016/J.Immuni.2008.04.010  0.88
2008 Lefrançois L, Lycke N. Isolation of mouse small intestinal intraepithelial lymphocytes, Peyer's patch, and lamina propria cells. Current Protocols in Immunology. Unit 3.19. PMID 18432783 DOI: 10.1002/0471142735.Im0319S17  0.353
2008 Khanna KM, Lefrançois L. Geography and plumbing control the T cell response to infection. Immunology and Cell Biology. 86: 416-22. PMID 18392042 DOI: 10.1038/Icb.2008.22  0.787
2007 McAleer JP, Zammit DJ, Lefrançois L, Rossi RJ, Vella AT. The lipopolysaccharide adjuvant effect on T cells relies on nonoverlapping contributions from the MyD88 pathway and CD11c+ cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 6524-35. PMID 17982041 DOI: 10.4049/Jimmunol.179.10.6524  0.56
2007 Khanna KM, McNamara JT, Lefrançois L. In situ imaging of the endogenous CD8 T cell response to infection. Science (New York, N.Y.). 318: 116-20. PMID 17916739 DOI: 10.1126/Science.1146291  0.815
2007 Blair DA, Lefrançois L. Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 15045-50. PMID 17827281 DOI: 10.1073/Pnas.0703767104  0.787
2007 Hagymasi AT, Slaiby AM, Mihalyo MA, Qui HZ, Zammit DJ, Lefrancois L, Adler AJ. Steady state dendritic cells present parenchymal self-antigen and contribute to, but are not essential for, tolerization of naive and Th1 effector CD4 cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 1524-31. PMID 17641018 DOI: 10.4049/Jimmunol.179.3.1524  0.568
2007 Marzo AL, Yagita H, Lefrançois L. Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 36-40. PMID 17579018 DOI: 10.4049/Jimmunol.179.1.36  0.544
2007 Srinivasan A, Salazar-Gonzalez RM, Jarcho M, Sandau MM, Lefrancois L, McSorley SJ. Innate immune activation of CD4 T cells in salmonella-infected mice is dependent on IL-18. Journal of Immunology (Baltimore, Md. : 1950). 178: 6342-9. PMID 17475863 DOI: 10.4049/Jimmunol.178.10.6342  0.635
2007 Turner DL, Cauley LS, Khanna KM, Lefrançois L. Persistent antigen presentation after acute vesicular stomatitis virus infection. Journal of Virology. 81: 2039-46. PMID 17151119 DOI: 10.1128/Jvi.02167-06  0.836
2006 Klonowski KD, Marzo AL, Williams KJ, Lee SJ, Pham QM, Lefrançois L. CD8 T cell recall responses are regulated by the tissue tropism of the memory cell and pathogen. Journal of Immunology (Baltimore, Md. : 1950). 177: 6738-46. PMID 17082587 DOI: 10.4049/Jimmunol.177.10.6738  0.611
2006 Stoklasek TA, Schluns KS, Lefrançois L. Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo. Journal of Immunology (Baltimore, Md. : 1950). 177: 6072-80. PMID 17056533 DOI: 10.4049/Jimmunol.177.9.6072  0.803
2006 Moyron-Quiroz JE, Rangel-Moreno J, Hartson L, Kusser K, Tighe MP, Klonowski KD, Lefrançois L, Cauley LS, Harmsen AG, Lund FE, Randall TD. Persistence and responsiveness of immunologic memory in the absence of secondary lymphoid organs. Immunity. 25: 643-54. PMID 17045819 DOI: 10.1016/J.Immuni.2006.08.022  0.488
2006 Klonowski KD, Williams KJ, Marzo AL, Lefrançois L. Cutting edge: IL-7-independent regulation of IL-7 receptor alpha expression and memory CD8 T cell development. Journal of Immunology (Baltimore, Md. : 1950). 177: 4247-51. PMID 16982855 DOI: 10.4049/Jimmunol.177.7.4247  0.58
2006 Yadav R, Zammit DJ, Lefrancois L, Vella AT. Effects of LPS-mediated bystander activation in the innate immune system. Journal of Leukocyte Biology. 80: 1251-61. PMID 16973890 DOI: 10.1189/Jlb.0406253  0.381
2006 Lefrançois L, Marzo AL. The descent of memory T-cell subsets. Nature Reviews. Immunology. 6: 618-23. PMID 16868553 DOI: 10.1038/Nri1866  0.565
2006 Lefrançois L. Development, trafficking, and function of memory T-cell subsets. Immunological Reviews. 211: 93-103. PMID 16824120 DOI: 10.1111/J.0105-2896.2006.00393.X  0.518
2006 Tan X, Lefrançois L. Novel IL-15 isoforms generated by alternative splicing are expressed in the intestinal epithelium. Genes and Immunity. 7: 407-16. PMID 16791279 DOI: 10.1038/Sj.Gene.6364314  0.591
2006 Cose S, Brammer C, Zammit DJ, Blair DA, Lefrançois L. CD4 T cells inhibit the CD8 T cell response during low-dose virus infection. International Immunology. 18: 1285-93. PMID 16769750 DOI: 10.1093/Intimm/Dxl061  0.626
2006 Salazar-Gonzalez RM, Niess JH, Zammit DJ, Ravindran R, Srinivasan A, Maxwell JR, Stoklasek T, Yadav R, Williams IR, Gu X, McCormick BA, Pazos MA, Vella AT, Lefrancois L, Reinecker HC, et al. CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer's patches. Immunity. 24: 623-32. PMID 16713979 DOI: 10.1016/J.Immuni.2006.02.015  0.831
2006 Cose S, Brammer C, Khanna KM, Masopust D, Lefrançois L. Evidence that a significant number of naive T cells enter non-lymphoid organs as part of a normal migratory pathway. European Journal of Immunology. 36: 1423-33. PMID 16708400 DOI: 10.1002/Eji.200535539  0.831
2006 Zammit DJ, Turner DL, Klonowski KD, Lefrançois L, Cauley LS. Residual antigen presentation after influenza virus infection affects CD8 T cell activation and migration. Immunity. 24: 439-49. PMID 16618602 DOI: 10.1016/J.Immuni.2006.01.015  0.699
2006 Lefrançois L, Puddington L. Intestinal and pulmonary mucosal T cells: local heroes fight to maintain the status quo. Annual Review of Immunology. 24: 681-704. PMID 16551263 DOI: 10.1146/Annurev.Immunol.24.021605.090650  0.502
2006 Zammit DJ, Lefrançois L. Dendritic cell-T cell interactions in the generation and maintenance of CD8 T cell memory. Microbes and Infection / Institut Pasteur. 8: 1108-15. PMID 16549379 DOI: 10.1016/J.Micinf.2005.12.002  0.642
2006 Myers L, Lee SW, Rossi RJ, Lefrancois L, Kwon BS, Mittler RS, Croft M, Vella AT. Combined CD137 (4-1BB) and adjuvant therapy generates a developing pool of peptide-specific CD8 memory T cells. International Immunology. 18: 325-33. PMID 16373363 DOI: 10.1093/Intimm/Dxh371  0.596
2005 Marzo AL, Klonowski KD, Le Bon A, Borrow P, Tough DF, Lefrançois L. Initial T cell frequency dictates memory CD8+ T cell lineage commitment. Nature Immunology. 6: 793-9. PMID 16025119 DOI: 10.1038/Ni1227  0.583
2005 Schluns KS, Stoklasek T, Lefrançois L. The roles of interleukin-15 receptor alpha: trans-presentation, receptor component, or both? The International Journal of Biochemistry & Cell Biology. 37: 1567-71. PMID 15896666 DOI: 10.1016/J.Biocel.2005.02.017  0.779
2005 Zammit DJ, Cauley LS, Pham QM, Lefrançois L. Dendritic cells maximize the memory CD8 T cell response to infection. Immunity. 22: 561-70. PMID 15894274 DOI: 10.1016/J.Immuni.2005.03.005  0.644
2005 Klonowski KD, Lefrançois L. The CD8 memory T cell subsystem: integration of homeostatic signaling during migration. Seminars in Immunology. 17: 219-29. PMID 15826827 DOI: 10.1016/J.Smim.2005.02.004  0.622
2004 Sandau MM, Schluns KS, Lefrancois L, Jameson SC. Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 6537-41. PMID 15557143 DOI: 10.4049/Jimmunol.173.11.6537  0.445
2004 D'Souza WN, Lefrançois L. Frontline: An in-depth evaluation of the production of IL-2 by antigen-specific CD8 T cells in vivo. European Journal of Immunology. 34: 2977-85. PMID 15384078 DOI: 10.1002/Eji.200425485  0.855
2004 Liu Z, Lefrançois L. Intestinal epithelial antigen induces mucosal CD8 T cell tolerance, activation, and inflammatory response. Journal of Immunology (Baltimore, Md. : 1950). 173: 4324-30. PMID 15383561 DOI: 10.4049/Jimmunol.173.7.4324  0.637
2004 Marzo AL, Vezys V, Klonowski KD, Lee SJ, Muralimohan G, Moore M, Tough DF, Lefrançois L. Fully functional memory CD8 T cells in the absence of CD4 T cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 969-75. PMID 15240684 DOI: 10.4049/Jimmunol.173.2.969  0.813
2004 Klonowski KD, Williams KJ, Marzo AL, Blair DA, Lingenheld EG, Lefrançois L. Dynamics of blood-borne CD8 memory T cell migration in vivo. Immunity. 20: 551-62. PMID 15142524 DOI: 10.1016/S1074-7613(04)00103-7  0.719
2004 Masopust D, Vezys V, Usherwood EJ, Cauley LS, Olson S, Marzo AL, Ward RL, Woodland DL, Lefrançois L. Activated primary and memory CD8 T cells migrate to nonlymphoid tissues regardless of site of activation or tissue of origin. Journal of Immunology (Baltimore, Md. : 1950). 172: 4875-82. PMID 15067066 DOI: 10.4049/Jimmunol.172.8.4875  0.865
2004 Schluns KS, Nowak EC, Cabrera-Hernandez A, Puddington L, Lefrançois L, Aguila HL. Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression. Proceedings of the National Academy of Sciences of the United States of America. 101: 5616-21. PMID 15060278 DOI: 10.1073/Pnas.0307442101  0.497
2004 Schluns KS, Klonowski KD, Lefrançois L. Transregulation of memory CD8 T-cell proliferation by IL-15Ralpha+ bone marrow-derived cells. Blood. 103: 988-94. PMID 14512307 DOI: 10.1182/Blood-2003-08-2814  0.595
2003 D'Souza WN, Lefrançois L. IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion. Journal of Immunology (Baltimore, Md. : 1950). 171: 5727-35. PMID 14634080 DOI: 10.4049/Jimmunol.171.11.5727  0.837
2003 Lefrançois L, Marzo A, Williams K. Sustained response initiation is required for T cell clonal expansion but not for effector or memory development in vivo. Journal of Immunology (Baltimore, Md. : 1950). 171: 2832-9. PMID 12960304 DOI: 10.4049/Jimmunol.171.6.2832  0.54
2003 Masopust D, Lefrançois L. CD8 T-cell memory: the other half of the story. Microbes and Infection / Institut Pasteur. 5: 221-6. PMID 12681411 DOI: 10.1016/S1286-4579(03)00014-5  0.766
2003 Schluns KS, Lefrançois L. Cytokine control of memory T-cell development and survival. Nature Reviews. Immunology. 3: 269-79. PMID 12669018 DOI: 10.1038/Nri1052  0.64
2003 Liu Z, Lefrancois L. Mucosal CD8 T cell activation and induction of inflammation to intestinal epithelial cell antigen Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)80124-5  0.603
2002 Vezys V, Lefrançois L. Cutting edge: inflammatory signals drive organ-specific autoimmunity to normally cross-tolerizing endogenous antigen. Journal of Immunology (Baltimore, Md. : 1950). 169: 6677-80. PMID 12471097 DOI: 10.4049/Jimmunol.169.12.6677  0.75
2002 Lefrançois L, Marzo AL, Masopust D, Schluns KS, Vezy V. Migration of primary and memory CD8 T cells. Advances in Experimental Medicine and Biology. 512: 141-6. PMID 12405198 DOI: 10.1007/978-1-4615-0757-4_19  0.759
2002 Lefrançois L. Dual personality of memory T cells. Trends in Immunology. 23: 226-8. PMID 12102732 DOI: 10.1016/S1471-4906(02)02190-7  0.513
2002 Lefrançois L, Masopust D. T cell immunity in lymphoid and non-lymphoid tissues. Current Opinion in Immunology. 14: 503-8. PMID 12088686 DOI: 10.1016/S0952-7915(02)00360-6  0.735
2002 Prlic M, Lefrancois L, Jameson SC. Multiple choices: regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15. The Journal of Experimental Medicine. 195: F49-52. PMID 12070294 DOI: 10.1084/Jem.20020767  0.582
2002 D'Souza WN, Schluns KS, Masopust D, Lefrançois L. Essential role for IL-2 in the regulation of antiviral extralymphoid CD8 T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 168: 5566-72. PMID 12023352 DOI: 10.4049/Jimmunol.168.11.5566  0.865
2002 Schluns KS, Williams K, Ma A, Zheng XX, Lefrançois L. Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 4827-31. PMID 11994430 DOI: 10.4049/Jimmunol.168.10.4827  0.635
2002 Marzo AL, Vezys V, Williams K, Tough DF, Lefrançois L. Tissue-level regulation of Th1 and Th2 primary and memory CD4 T cells in response to Listeria infection. Journal of Immunology (Baltimore, Md. : 1950). 168: 4504-10. PMID 11970995 DOI: 10.4049/Jimmunol.168.9.4504  0.789
2002 Lefrançois L, Vezys V. Transgenic mouse model of intestine-specific mucosal injury and repair. Journal of the National Cancer Institute. Monographs. 21-5. PMID 11694561 DOI: 10.1093/Oxfordjournals.Jncimonographs.A003434  0.696
2001 Pope C, Kim SK, Marzo A, Masopust D, Williams K, Jiang J, Shen H, Lefrançois L. Organ-specific regulation of the CD8 T cell response to Listeria monocytogenes infection. Journal of Immunology (Baltimore, Md. : 1950). 166: 3402-9. PMID 11207297 DOI: 10.4049/Jimmunol.166.5.3402  0.752
2001 Masopust D, Jiang J, Shen H, Lefrançois L. Direct analysis of the dynamics of the intestinal mucosa CD8 T cell response to systemic virus infection Journal of Immunology. 166: 2348-2356. PMID 11160292 DOI: 10.4049/Jimmunol.166.4.2348  0.727
2000 Schluns KS, Kieper WC, Jameson SC, Lefrançois L. Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. Nature Immunology. 1: 426-32. PMID 11062503 DOI: 10.1038/80868  0.662
2000 Vezys V, Olson S, Lefrançois L. Expression of intestine-specific antigen reveals novel pathways of CD8 T cell tolerance induction. Immunity. 12: 505-14. PMID 10843383 DOI: 10.1016/S1074-7613(00)80202-2  0.785
2000 Laky K, Lefrançois L, Lingenheld EG, Ishikawa H, Lewis JM, Olson S, Suzuki K, Tigelaar RE, Puddington L. Enterocyte expression of interleukin 7 induces development of gammadelta T cells and Peyer's patches. The Journal of Experimental Medicine. 191: 1569-80. PMID 10790431 DOI: 10.1084/Jem.191.9.1569  0.513
1999 Lefrançois L, Olson S, Masopust D. A critical role for CD40-CD40 ligand interactions in amplification of the mucosal CD8 T cell response Journal of Experimental Medicine. 190: 1275-1283. PMID 10544199 DOI: 10.1084/Jem.190.9.1275  0.765
1999 Schober SL, Kuo CT, Schluns KS, Lefrancois L, Leiden JM, Jameson SC. Expression of the transcription factor lung Krüppel-like factor is regulated by cytokines and correlates with survival of memory T cells in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 163: 3662-7. PMID 10490960  0.506
1999 Lefrançois L, Parker CM, Olson S, Muller W, Wagner N, Schön MP, Puddington L. The role of beta7 integrins in CD8 T cell trafficking during an antiviral immune response. The Journal of Experimental Medicine. 189: 1631-8. PMID 10330442 DOI: 10.1084/Jem.189.10.1631  0.562
1998 Lefrancois L, Puddington L. Anatomy of T-cell development in the intestine Gastroenterology. 115: 1588-1591. PMID 9834291 DOI: 10.1016/S0016-5085(98)70042-3  0.508
1998 Kadlecek TA, Van Oers NSC, Lefrancois L, Olson S, Finlay D, Chu DH, Connolly K, Killeen N, Weiss A. Differential requirements for ZAP-70 in TCR signaling and T cell development Journal of Immunology. 161: 4688-4694. PMID 9794398  0.477
1998 Reed DS, Olson S, Lefrançois L. Glycosyltransferase regulation mediated by pre-TCR signaling in early thymocyte development. International Immunology. 10: 445-51. PMID 9620600 DOI: 10.1093/Intimm/10.4.445  0.492
1997 Lefrançois L, Fuller B, Huleatt JW, Olson S, Puddington L. On the front lines: intraepithelial lymphocytes as primary effectors of intestinal immunity. Springer Seminars in Immunopathology. 18: 463-75. PMID 9144865 DOI: 10.1007/Bf00824053  0.331
1996 Huleatt JW, Lefrançois L. Beta2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment. Immunity. 5: 263-73. PMID 8808681 DOI: 10.1016/S1074-7613(00)80321-0  0.429
1996 Lefrançois L, Puddington L. The role of the thymus in intestinal intraepithelial T-cell development. Annals of the New York Academy of Sciences. 778: 36-46. PMID 8610990 DOI: 10.1111/J.1749-6632.1996.Tb21112.X  0.508
1995 Lefrançois L, Puddington L. Extrathymic intestinal T-cell development: virtual reality? Immunology Today. 16: 16-21. PMID 7880383 DOI: 10.1016/0167-5699(95)80065-4  0.523
1995 Huleatt JW, Lefrancois L. Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo Journal of Immunology. 154: 5684-5693. PMID 7751620  0.471
1995 Fuller B, Lefrancois L. Requirement for extrathymic class I histocompatibility antigens for positive selection of thymus-derived T lymphocytes Journal of Immunology. 155: 2808-2811. PMID 7673696  0.482
1995 Puddington L, Olson S, Lefrançois L. Interactions between stem cell factor and c-Kit are required for intestinal immune system homeostasis. Immunity. 1: 733-9. PMID 7534619 DOI: 10.1016/S1074-7613(94)80015-4  0.429
1994 Tsuji M, Mombaerts P, Lefrancois L, Nussenzweig RS, Zavala F, Tonegawa S. Gamma delta T cells contribute to immunity against the liver stages of malaria in alpha beta T-cell-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 345-9. PMID 8278391 DOI: 10.1073/Pnas.91.1.345  0.495
1994 Lefrançois L, Barrett TA, Havran WL, Puddington L. Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells. European Journal of Immunology. 24: 635-40. PMID 7907296 DOI: 10.1002/Eji.1830240322  0.487
1993 Kelly KA, Pearse M, Lefrancois L, Scollay R. Emigration of selected subsets of γδ+ T cells from the adult murine thymus International Immunology. 5: 331-335. PMID 8494820 DOI: 10.1093/Intimm/5.4.331  0.545
1993 Badiner G, Goodman TG, Lefrançois L. Selection of intestinal intraepithelial lymphocyte T cell receptors: evidence for a dynamic tissue-specific process. International Immunology. 5: 223-6. PMID 8452818 DOI: 10.1093/Intimm/5.2.223  0.456
1993 Gramzinski RA, Adams E, Gross JA, Goodman TG, Allison JP, Lefrançois L. T cell receptor-triggered activation of intraepithelial lymphocytes in vitro. International Immunology. 5: 145-53. PMID 8383994 DOI: 10.1093/Intimm/5.2.145  0.508
1992 Lefrançois L. Extrathymic differentiation of intraepithelial lymphocytes: generation of a separate and unequal T-cell repertoire? Immunology Today. 12: 436-8. PMID 1786079 DOI: 10.1016/0167-5699(91)90015-L  0.541
1992 Barrett TA, Delvy ML, Kennedy DM, Lefrancois L, Matis LA, Dent AL, Hedrick SM, Bluestone JA. Mechanism of self-tolerance of gamma/delta T cells in epithelial tissue. The Journal of Experimental Medicine. 175: 65-70. PMID 1730927 DOI: 10.1084/Jem.175.1.65  0.362
1992 Lefrançois L. Maturation, selection and specificity of Tcryδ T cells Immunologic Research. 11: 54-65. PMID 1534829 DOI: 10.1007/Bf02918608  0.506
1992 Goodman T, LeCorre R, Lefrancois L. A T-cell receptor γδ-specific monoclonal antibody detects a Vγ5 region polymorphism Immunogenetics. 35: 65-68. PMID 1345907 DOI: 10.1007/Bf00216631  0.395
1991 Lefrancois L. Increased usage of Vδ4+ T cell receptors by intestinal intraepithelial lymphocytes is regulated by class II major histocompatibility complex Immunologic Research. 10: 334-340. PMID 1835487 DOI: 10.1007/Bf02919718  0.425
1991 Lefrancois L, LeCorre R, Mayo J, Bluestone JA, Goodman T. Selection of Vδ+ T cell receptors of intestinal intraepithelial lymphocytes is dependent on Class II histocompatibility antigen expression Current Topics in Microbiology and Immunology. 173: 255-267. PMID 1833152 DOI: 10.1007/978-3-642-76492-9_36  0.48
1991 Chang HL, Lefrancois L, Zaroukian MH, Esselman WJ. Developmental expression of CD45 alternate exons in murine T cells: Evidence of additional alternate exon use Journal of Immunology. 147: 1687-1693. PMID 1831832  0.41
1991 Lefrancois L. Phenotypic complexity of intraepithelial lymphocytes of the small intestine Journal of Immunology. 147: 1746-1751. PMID 1716278  0.338
1990 Lefrancois L, LeCorre R, Mayo J, Bluestone JA, Goodman T. Extrathymic selection of TCR γδ+ T cells by class II major histocompatibility complex molecules Cell. 63: 333-340. PMID 2208290 DOI: 10.1016/0092-8674(90)90166-C  0.423
1990 Reardon C, Lefrancois L, Farr A, Kubo R, O'Brien R, Born W. Expression of γ/δ T cell receptors on lymphocytes from the lactating mammary gland Journal of Experimental Medicine. 172: 1263-1266. PMID 2145390 DOI: 10.1084/jem.172.4.1263  0.394
1990 Goodman TG, Chang HL, Esselman WJ, LeCorre R, Lefrancois L. Characterization of the CD45 molecule on murine intestinal intraepithelial lymphocytes Journal of Immunology. 145: 2959-2966. PMID 1976708  0.33
1989 Goodman T, Lefrancois L. Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function Journal of Experimental Medicine. 170: 1569-1581. PMID 2572671 DOI: 10.1084/Jem.170.5.1569  0.392
1989 Lefrancois L, Goodman T. In vivo modulation of cytolytic activity and Thy-1 expression in TCR-γδ+ intraepithelial lymphocytes Science. 243: 1716-1718. PMID 2564701 DOI: 10.1126/Science.2564701  0.538
1989 Asarnow DM, Goodman T, LeFrancois L, Allison JP. Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells Nature. 341: 60-62. PMID 2528075 DOI: 10.1038/341060A0  0.411
1988 Goodman T, Lefrançois L. Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes Nature. 333: 855-858. PMID 2968521 DOI: 10.1038/333855A0  0.57
1987 Lefrancois L, Goodman T. Developmental sequence of T200 antigen modifications in murine T cells Journal of Immunology. 139: 3718-3724. PMID 2960741  0.43
1987 Lefrancois L. Expression of carbohydrate differentiation antigens during ontogeny of the murine thymus Journal of Immunology. 139: 2220-2229. PMID 2443563  0.329
1987 Lefrancois L. Carbohydrate differentiation antigens of murine T cells: Expression on intestinal lymphocytes and intestinal epithelium Journal of Immunology. 138: 3375-3384. PMID 2437191  0.389
1986 Yewdell JW, Bennink JR, Mackett M, Lefrancois L, Lyles DS, Moss B. Recognition of cloned vesicular stomatitis virus internal and external gene products by cytotoxic T lymphocytes. The Journal of Experimental Medicine. 163: 1529-38. PMID 3011949 DOI: 10.1084/Jem.163.6.1529  0.61
1986 Lefrancois L, Thomas ML, Bevan MJ, Trowbridge IS. Different classes of T lymphocytes have different mRNAs for the leukocyte-common antigen, T200 Journal of Experimental Medicine. 163: 1337-1342. PMID 2939172 DOI: 10.1084/Jem.163.5.1337  0.682
1986 Lefrancois L, Kanagawa O. Coordinate expression of cytolytic activity and cytotoxic T cell-specific carbohydrate antigens in a T cell hybridoma Journal of Immunology. 136: 1171-1177. PMID 2418106  0.314
1985 Lefrancois L, Bevan MJ. Novel antigenic determinants of the T200 glycoprotein expressed preferentially by activated cytotoxic T lymphocytes Journal of Immunology. 135: 374-383. PMID 2582040  0.39
1985 Lefrançois L, Bevan MJ. Functional modifications of cytotoxic T-lymphocyte T200 glycoprotein recognized by monoclonal antibodies. Nature. 314: 449-52. PMID 2580241 DOI: 10.1038/314449A0  0.657
1985 Klein JR, Lefrancois L, Kagnoff MF. A murine cytotoxic T lymphocyte clone from the intestinal mucosa that is antigen specific for proliferation and displays broadly reactive inducible cytotoxic activity Journal of Immunology. 135: 3697-3703. PMID 2415582  0.4
1985 Lefrancois L, Puddington L, Machamer CE, Bevan MJ. Acquisition of cytotoxic T lymphocyte-specific carbohydrate differentiation antigens Journal of Experimental Medicine. 162: 1275-1293. PMID 2413157 DOI: 10.1084/Jem.162.4.1275  0.598
1985 Lefrançois L, Bevan MJ. Functional modifications of cytotoxic T-lymphocyte T200 glycoprotein recognized by monoclonal antibodies Nature. 315: 254-254. DOI: 10.1038/315254b0  0.58
1984 Lefrancois L, Klein JR, Paetkau V, Bevan MJ. Antigen-independent activation of memory cytotoxic T cells by interleukin 2 Journal of Immunology. 132: 1845-1850. PMID 6230394  0.401
1984 LeFrancois L, Bevan MJ. A reexamination of the role of Lyt-2-positive T cells in murine skin graft rejection Journal of Experimental Medicine. 159: 57-67. PMID 6198428 DOI: 10.1084/Jem.159.1.57  0.58
1983 Lefrancois L, Lyles DS. Cytotoxic T lymphocytes reactive with vesicular stomatitis virus: analysis of specificity with monoclonal antibodies directed to the viral glycoprotein. Journal of Immunology (Baltimore, Md. : 1950). 130: 1408-12. PMID 6185583  0.588
1983 Lefrancois L, Lyles DS. Antigenic determinants of vesicular stomatitis virus: analysis with antigenic variants. Journal of Immunology (Baltimore, Md. : 1950). 130: 394-8. PMID 6183358  0.514
1982 Lefrancois L, Lyles DS. The interaction of antibody with the major surface glycoprotein of vesicular stornatitis virus II. Monoclonal antibodies to nonneutralizing and cross-reactive epitopes of Indiana and New Jersey serotypes Virology. 121: 168-174. PMID 6180551 DOI: 10.1016/0042-6822(82)90126-X  0.501
1982 Lefrancois L, Lyles DS. The interaction of antibody with the major surface glycoprotein of vesicular stomatitis virus I. Analysis of neutralizing epitopes with monoclonal antibodies Virology. 121: 157-167. PMID 6180550 DOI: 10.1016/0042-6822(82)90125-8  0.498
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