Robert Barchi - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
General Biophysics, Neuroscience Biology

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Barchi RL. Molecular biology of voltage-dependent potassium and sodium channels The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0012  0.363
2002 Kleopa KA, Barchi RL. Genetic disorders of neuromuscular ion channels. Muscle & Nerve. 26: 299-325. PMID 12210360 DOI: 10.1002/mus.10164  0.39
2000 Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA. Nomenclature of voltage-gated sodium channels. Neuron. 28: 365-8. PMID 11144347 DOI: 10.1016/S0896-6273(00)00116-1  0.352
1998 Barchi RL. Ion channel mutations affecting muscle and brain Current Opinion in Neurology. 11: 461-468. PMID 9847995 DOI: 10.1097/00019052-199810000-00008  0.426
1998 Kraner SD, Filatov GN, Sun W, Bannerman P, Lindstrom J, Barchi RL. Analysis of local structure in the D2/S1-S2 region of the rat skeletal muscle type 1 sodium channel using insertional mutagenesis. Journal of Neurochemistry. 70: 1628-35. PMID 9523580 DOI: 10.1046/J.1471-4159.1998.70041628.X  0.41
1998 Rich MM, Pinter MJ, Kraner SD, Barchi RL. Loss of electrical excitability in an animal model of acute quadriplegic myopathy. Annals of Neurology. 43: 171-9. PMID 9485058 DOI: 10.1002/ana.410430207  0.417
1997 Barchi RL. Ion channel mutations and diseases of skeletal muscle Neurobiology of Disease. 4: 254-264. PMID 9361302  0.469
1996 Ji S, George AL, Horn R, Barchi RL. Paramyotonia congenita mutations reveal different roles for segments S3 and S4 of domain D4 in hSkM1 sodium channel gating. The Journal of General Physiology. 107: 183-94. PMID 8833340 DOI: 10.1085/jgp.107.2.183  0.329
1995 Sun W, Cohen SA, Barchi RL. Localization of epitopes for monoclonal antibodies directed against the adult rat skeletal muscle sodium channel (rSkM1) using polymerase chain reaction, fusion proteins, and western blotting Analytical Biochemistry. 226: 188-191. PMID 7785772 DOI: 10.1006/abio.1995.1210  0.357
1995 Barchi RL. Molecular pathology of the skeletal muscle sodium channel Annual Review of Physiology. 57: 355-385. PMID 7778872  0.457
1995 Ji S, George AL, Horn R, Barchi RL. Sodium channel mutations and disorders of excitation in human skeletal muscle. Society of General Physiologists Series. 50: 61-76. PMID 7676325  0.376
1995 Sun W, Barchi RL, Cohen SA. Probing sodium channel cytoplasmic domain structure: Evidence for the interaction of the rSkM1 amino and carboxyl termini Journal of Biological Chemistry. 270: 22271-22276. PMID 7673207 DOI: 10.1074/jbc.270.38.22271  0.349
1995 Ji S, George AL, Horn R, Barchi RL. Sodium channel mutations and disorders of excitation in human skeletal muscle Journal of General Physiology. 64-76.  0.376
1994 Sheng ZH, Zhang H, Barchi RL, Kallen RG. Molecular cloning and functional analysis of the promoter of rat skeletal muscle voltage-sensitive sodium channel subtype 2 (rSkM2): evidence for muscle-specific nuclear protein binding to the core promoter. Dna and Cell Biology. 13: 9-23. PMID 8286044  0.412
1994 Krafte DS, Davison K, Dugrenier N, Estep K, Josef K, Barchi RL, Kallen RG, Silver PJ, Ezrin AM. Pharmacological modulation of human cardiac Na+ channels. European Journal of Pharmacology. 266: 245-54. PMID 8174607 DOI: 10.1016/0922-4106(94)90133-3  0.317
1994 Chahine M, George AL, Zhou M, Ji S, Sun W, Barchi RL, Horn R. Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation. Neuron. 12: 281-94. PMID 8110459 DOI: 10.1016/0896-6273(94)90271-2  0.383
1994 Yang N, Ji S, Zhou M, Ptácek LJ, Barchi RL, Horn R, George AL. Sodium channel mutations in paramyotonia congenita exhibit similar biophysical phenotypes in vitro. Proceedings of the National Academy of Sciences of the United States of America. 91: 12785-9. PMID 7809121 DOI: 10.1073/Pnas.91.26.12785  0.398
1993 Ptacek LJ, Gouw L, Kwieciński H, McManis P, Mendell JR, Barohn RJ, George AL, Barchi RL, Robertson M, Leppert MF. Sodium channel mutations in paramyotonia congenita and hyperkalemic periodic paralysis Annals of Neurology. 33: 300-307. PMID 8388676 DOI: 10.1002/ana.410330312  0.4
1993 Cohen SA, Barchi RL. Voltage-dependent sodium channels International Review of Cytology. 137: 55-103. PMID 8387472  0.407
1993 George AL, Iyer GS, Kleinfield R, Kallen RG, Barchi RL. Genomic organization of the human skeletal muscle sodium channel gene. Genomics. 15: 598-606. PMID 8385647 DOI: 10.1006/geno.1993.1113  0.435
1993 Yang JS, Bennett PB, Makita N, George AL, Barchi RL. Expression of the sodium channel β1 subunit in rat skeletal muscle is selectively associated with the tetrodotoxin-sensitive α subunit isoform Neuron. 11: 915-922. PMID 8240813 DOI: 10.1016/0896-6273(93)90121-7  0.341
1993 Kallen RG, Cohen SA, Barchi RL. Structure, function and expression of voltage-dependent sodium channels Molecular Neurobiology. 7: 383-428. PMID 8179845 DOI: 10.1007/BF02769184  0.404
1993 Barchi RL. Ion channels and disorders of excitation in skeletal muscle Current Opinion in Neurology and Neurosurgery. 6: 40-47. PMID 7679017  0.432
1992 Cohen SA, Barchi RL. Localization of epitopes for antibodies that differentially label sodium channels in skeletal muscle surface and T-tubular membranes The Journal of Membrane Biology. 128: 219-226. PMID 1380092 DOI: 10.1007/BF00231814  0.301
1992 Chen LQ, Chahine M, Kallen RG, Barchi RL, Horn R. Chimeric study of sodium channels from rat skeletal and cardiac muscle. Febs Letters. 309: 253-7. PMID 1325372 DOI: 10.1016/0014-5793(92)80783-D  0.379
1992 Chahine M, Chen LQ, Kallen RG, Barchi RL, Horn R. Expressed Na channel clones differ in their sensitivity to external calcium concentration. Biophysical Journal. 62: 37-40. PMID 1318104 DOI: 10.1016/S0006-3495(92)81771-X  0.302
1992 Ptáček LJ, George AL, Barchi RL, Griggs RC, Riggs JE, Robertson M, Leppert MF. Mutations in an S4 segment of the adult skeletal muscle sodium channel cause paramyotonia congenita Neuron. 8: 891-897. PMID 1316765 DOI: 10.1016/0896-6273(92)90203-P  0.328
1992 George AL, Komisarof J, Kallen RG, Barchi RL. Primary structure of the adult human skeletal muscle voltage‐dependent sodium channel Annals of Neurology. 31: 131-137. PMID 1315496 DOI: 10.1002/ana.410310203  0.464
1992 Gellens ME, George AL, Chen LQ, Chahine M, Horn R, Barchi RL, Kallen RG. Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 89: 554-8. PMID 1309946 DOI: 10.1073/Pnas.89.2.554  0.467
1992 Cohen SA, Barchi RL. Cardiac sodium channel structure and function Trends in Cardiovascular Medicine. 2: 133-140. DOI: 10.1016/1050-1738(92)90020-S  0.474
1992 Barchi RL. Sodium channel gene defects in the periodic paralyses Current Opinion in Neurobiology. 2: 852. DOI: 10.1016/0959-4388(92)90031-F  0.327
1991 White MM, Chen LQ, Kleinfield R, Kallen RG, Barchi RL. SkM2, a Na+ channel cDNA clone from denervated skeletal muscle, encodes a tetrodotoxin-insensitive Na+ channel. Molecular Pharmacology. 39: 604-8. PMID 1851958  0.468
1991 George AL, David Ledbetter H, Kallen RG, Barchi RL. Assignment of a human skeletal muscle sodium channel α-subunit gene (SCN4A) to 17q23.1-25.3 Genomics. 9: 555-556. PMID 1851726 DOI: 10.1016/0888-7543(91)90425-E  0.38
1991 Schotland DL, Fieles W, Barchi RL. Expression of sodium channel subtypes during development in rat skeletal muscle Muscle and Nerve. 14: 142-151. PMID 1847990 DOI: 10.1002/mus.880140209  0.415
1991 Zwerling SJ, Cohen SA, Barchi RL. Analysis of protease-sensitive regions in the skeletal muscle sodium channel in vitro and implications for channel tertiary structure Journal of Biological Chemistry. 266: 4574-4580. PMID 1847924  0.433
1991 Barchi RL. Molecular aspects of voltage-dependent ion channels Advances in Experimental Medicine and Biology. 308: 107-117. PMID 1724871  0.337
1991 Ebers GC, George AL, Barchi RL, Ting‐Passador SS, Kallen RG, Lathrop GM, Beckman JS, Hahn AF, Brown WF, Campbell RD, Hudson AJ. Paramyotonia congenita and hyperkalemic periodic paralysis are linked to the adult muscle sodium channel gene Annals of Neurology. 30: 810-816. PMID 1686388 DOI: 10.1002/ana.410300610  0.408
1991 Ebers GC, Hudson AJ, George AL, Barchi RL, Kallen RG. RFLP for BgIII at the human skeletal muscle sodium channel locus Nucleic Acids Research. 19: 1166. PMID 1673563 DOI: 10.1093/Nar/19.5.1166-A  0.477
1991 Ptáček LJ, George AL, Griggs RC, Tawil R, Kallen RG, Barchi RL, Robertson M, Leppert MF. Identification of a mutation in the gene causing hyperkalemic periodic paralysis Cell. 67: 1021-1027. PMID 1659948 DOI: 10.1016/0092-8674(91)90374-8  0.305
1991 Yang JSJ, Sladky JT, Kallen RG, Barchi RL. TTX-sensitive and TTX-insensitive sodium channel mRNA transcripts are independently regulated in adult skeletal muscle after denervation Neuron. 7: 421-427. PMID 1654949 DOI: 10.1016/0896-6273(91)90294-A  0.307
1991 Barchi RL. Bad channel genes and weak muscles Current Biology. 1: 150-152. DOI: 10.1016/0960-9822(91)90216-J  0.427
1990 Kallen RG, Sheng ZH, Yang J, Chen LQ, Rogart RB, Barchi RL. Primary structure and expression of a sodium channel characteristic of denervated and immature rat skeletal muscle. Neuron. 4: 233-42. PMID 2155010 DOI: 10.1016/0896-6273(90)90098-Z  0.462
1990 Yang J, Barchi R. Phosphorylation of the Rat Skeletal Muscle Sodium Channel by Cyclic AMP‐Dependent Protein Kinase Journal of Neurochemistry. 54: 954-962. PMID 2154554 DOI: 10.1111/J.1471-4159.1990.Tb02343.X  0.465
1989 Trimmer JS, Cooperman SS, Tomiko SA, Zhou JY, Crean SM, Boyle MB, Kallen RG, Sheng ZH, Barchi RL, Sigworth FJ. Primary structure and functional expression of a mammalian skeletal muscle sodium channel. Neuron. 3: 33-49. PMID 2559760 DOI: 10.1016/0896-6273(89)90113-X  0.465
1989 Kraner S, Yang J, Barchi R. Structural inferences for the native skeletal muscle sodium channel as derived from patterns of endogenous proteolysis Journal of Biological Chemistry. 264: 13273-13280. PMID 2546950  0.456
1988 Barchi RL. Myotonia Neurologic Clinics. 6: 473-484. PMID 3065595  0.343
1988 Gordon RD, Li Y, Fieles WE, Schotland DL, Barchi RL. Topological localization of a segment of the eel voltage-dependent sodium channel primary sequence (AA 927-938) that discriminates between models of tertiary structure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 3742-9. PMID 2848108  0.43
1988 Barchi RL. Probing the molecular structure of the voltage-dependent sodium channel Annual Review of Neuroscience. 11: 455-495. PMID 2452597 DOI: 10.1146/Annurev.Ne.11.030188.002323  0.451
1988 Barchi RL. Chapter 12 Molecular Characteristics of Sodium Channels in Skeletal Muscle Current Topics in Membranes and Transport. 33: 251-270. DOI: 10.1016/S0070-2161(08)60902-8  0.464
1987 Cooperman SS, Grubman SA, Barchi RL, Goodman RH, Mandel G. Modulation of sodium-channel mRNA levels in rat skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 84: 8721-5. PMID 2446331 DOI: 10.1073/Pnas.84.23.8721  0.451
1987 Haimovich B, Schotland DL, Fieles WE, Barchi RL. Localization of sodium channel subtypes in adult rat skeletal muscle using channel-specific monoclonal antibodies. Journal of Neuroscience. 7: 2957-2966. PMID 2442326 DOI: 10.1523/Jneurosci.07-09-02957.1987  0.415
1987 Barchi RL, Casadei JM, Gordon RD, Roberts RH. Voltage-sensitive sodium channels: an evolving molecular view Society of General Physiologists Series. 41: 125-148. PMID 2436306  0.508
1987 Casadei JM, Barchi RL. Monoclonal Antibodies Against the Voltage‐Sensitive Sodium Channel from Rat Skeletal Muscle: Mapping Antibody Binding Sites Journal of Neurochemistry. 48: 773-778. PMID 2433396 DOI: 10.1111/j.1471-4159.1987.tb05584.x  0.325
1987 Gordon RD, Fieles WE, Schotland DL, Hogue-Angeletti R, Barchi RL. Topographical localization of the C-terminal region of the voltage-dependent sodium channel from Electrophorus electricus using antibodies raised against a synthetic peptide Proceedings of the National Academy of Sciences of the United States of America. 84: 308-312. PMID 2432607 DOI: 10.1073/pnas.84.1.308  0.379
1987 Barchi RL. Sodium channel diversity: subtle variations on a complex theme Trends in Neurosciences. 10: 221-223. DOI: 10.1016/0166-2236(87)90159-7  0.352
1986 Barchi RL. Biochemistry of sodium channels from mammalian muscle Annals of the New York Academy of Sciences. 179-185. PMID 2433990  0.486
1986 Haimovich B, Tanaka JC, Barchi RL. Developmental Appearance of Sodium Channel Subtypes in Rat Skeletal Muscle Cultures Journal of Neurochemistry. 47: 1148-1153. PMID 2427654 DOI: 10.1111/J.1471-4159.1986.Tb00733.X  0.397
1986 Casadei JM, Gordon RD, Barchi RL. Immunoaffinity isolation of Na+ channels from rat skeletal muscle. Analysis of subunits Journal of Biological Chemistry. 261: 4318-4323. PMID 2419342  0.471
1986 Furman RE, Tanaka JC, Mueller P, Barchi RL. Voltage-dependent activation in purified reconstituted sodium channels from rabbit T-tubular membranes Proceedings of the National Academy of Sciences of the United States of America. 83: 488-492. PMID 2417245 DOI: 10.1073/Pnas.83.2.488  0.489
1985 Kraner SD, Tanaka JC, Barchi RL. Purification and functional reconstitution of the voltage-sensitive sodium channel from rabbit T-tubular membranes. The Journal of Biological Chemistry. 260: 6341-7. PMID 2581954  0.407
1984 Casadei JM, Gordon RD, Lampson LA, Schotland DL, Barchi RL. Monoclonal antibodies against the voltage-sensitive Na+ channel from mammalian skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 81: 6227-31. PMID 6207539 DOI: 10.1073/Pnas.81.19.6227  0.449
1984 Barchi RL, Tanaka JC, Furman RE. Molecular characteristics and functional reconstitution of muscle voltage-sensitive sodium channels Journal of Cellular Biochemistry. 26: 135-146. PMID 6098588 DOI: 10.1002/Jcb.240260302  0.459
1984 Haimovich B, Bonilla E, Casadel J, Barchi R. Immunocytochemical localization of the mammalian voltage-dependent sodium channel using polyclonal antibodies against the purified protein Journal of Neuroscience. 4: 2259-2268. PMID 6090613 DOI: 10.1523/Jneurosci.04-09-02259.1984  0.531
1984 Barchi RL. Voltage-sensitive Na+ ion channels: molecular properties and functional reconstitution Trends in Biochemical Sciences. 9: 358-361. DOI: 10.1016/0968-0004(84)90060-4  0.478
1983 Tanaka JC, Eccleston JF, Barchi RL. Cation selectivity characteristics of the reconstituted voltage-dependent sodium channel purified from rat skeletal muscle sarcolemma Journal of Biological Chemistry. 258: 7519-7526. PMID 6305944  0.417
1983 Barchi RL. Protein components of the purified sodium channel from rat skeletal muscle sarcolemma Journal of Neurochemistry. 40: 1377-1385. PMID 6300333  0.36
1982 Weigele JB, Barchi RL. Functional reconstitution of the purified sodium channel protein from rat sarcolemma Proceedings of the National Academy of Sciences of the United States of America. 79: 3651-3655. PMID 6285356  0.373
1982 Barchi RL. Biochemical Studies of the Excitable Membrane Sodium Channel International Review of Neurobiology. 23: 69-101. DOI: 10.1016/S0074-7742(08)60622-4  0.423
1981 Barchi RL, Weigele JB, Cohen SA. Isolation of sodium channels from excitable tissues Advances in Neurology. 31: 377-389. PMID 6275672  0.326
1980 Barchi RL, Cohen SA, Murphy LE. Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 77: 1306-10. PMID 6246486  0.385
1980 Barchi RL, Murphy LE. Size characteristics of the solubilized sodium channel saxitoxin binding site from mammalian sarcolemma. Biochimica Et Biophysica Acta. 597: 391-8. PMID 6245695 DOI: 10.1016/0005-2736(80)90115-7  0.318
1979 Barchi RL, Weigele JB. Characteristics of saxitoxin binding to the sodium channel of sarcolemma isolated from rat skeletal muscle The Journal of Physiology. 295: 383-396. PMID 42783 DOI: 10.1113/jphysiol.1979.sp012975  0.317
1978 Weigele JB, Barchi RL. Saxitoxin binding to the mammalian sodium channel. Competition by monovalent and divalent cations Febs Letters. 95: 49-53. PMID 31301 DOI: 10.1016/0014-5793(78)80049-0  0.362
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