Robert Henry Roth - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Neuropsychopharmacology

377 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Blackburn JK, Curry DW, Thomsen AN, Roth RH, Elsworth JD. Pioglitazone activates paraoxonase-2 in the brain: A novel neuroprotective mechanism. Experimental Neurology. 113234. PMID 32044330 DOI: 10.1016/J.Expneurol.2020.113234  0.771
2017 Golub MS, Hackett EP, Hogrefe CE, Leranth C, Elsworth JD, Roth RH. Cognitive performance of juvenile monkeys after chronic fluoxetine treatment. Developmental Cognitive Neuroscience. 26: 52-61. PMID 28521247 DOI: 10.1016/J.Dcn.2017.04.008  0.659
2015 Bubak AN, Redmond DE, Elsworth JD, Roth RH, Collier TJ, Bjugstad KB, Blanchard BC, Sladek JR. A potential compensatory role for endogenous striatal tyrosine hydroxylase-positive neurons in a nonhuman primate model of Parkinson's disease. Cell Transplantation. 24: 673-80. PMID 25839107 DOI: 10.3727/096368915X687741  0.726
2015 Elsworth JD, Jentsch JD, Groman SM, Roth RH, Redmond ED, Leranth C. Low circulating levels of bisphenol-A induce cognitive deficits and loss of asymmetric spine synapses in dorsolateral prefrontal cortex and hippocampus of adult male monkeys. The Journal of Comparative Neurology. 523: 1248-57. PMID 25557059 DOI: 10.1002/Cne.23735  0.785
2015 Elsworth JD, Groman SM, Jentsch JD, Leranth C, Redmond DE, Kim JD, Diano S, Roth RH. Primate phencyclidine model of schizophrenia: sex-specific effects on cognition, brain derived neurotrophic factor, spine synapses, and dopamine turnover in prefrontal cortex. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522392 DOI: 10.1093/ijnp/pyu048  0.791
2014 Groman SM, James AS, Seu E, Tran S, Clark TA, Harpster SN, Crawford M, Burtner JL, Feiler K, Roth RH, Elsworth JD, London ED, Jentsch JD. In the blink of an eye: relating positive-feedback sensitivity to striatal dopamine D2-like receptors through blink rate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14443-54. PMID 25339755 DOI: 10.1523/Jneurosci.3037-14.2014  0.804
2014 Wakeman DR, Weiss S, Sladek JR, Elsworth JD, Bauereis B, Leranth C, Hurley PJ, Roth RH, Redmond DE. Survival and integration of neurons derived from human embryonic stem cells in MPTP-lesioned primates. Cell Transplantation. 23: 981-94. PMID 23562290 DOI: 10.3727/096368913X664865  0.727
2014 Deutch AY, Roth RH. Pharmacology and Biochemistry of Synaptic Transmission: Classical Transmitters From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience: Third Edition. 207-237. DOI: 10.1016/B978-0-12-397179-1.00007-5  0.456
2013 Elsworth JD, Roth RH. Pregnancy, a risky time: keep calm, clean, and carry on! Biological Psychiatry. 74: 478-9. PMID 24034364 DOI: 10.1016/J.Biopsych.2013.07.027  0.611
2013 Redmond DE, McEntire CR, Kingsbery JP, Leranth C, Elsworth JD, Bjugstad KB, Roth RH, Samulski RJ, Sladek JR. Comparison of fetal mesencephalic grafts, AAV-delivered GDNF, and both combined in an MPTP-induced nonhuman primate Parkinson's model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2160-8. PMID 23913185 DOI: 10.1038/Mt.2013.180  0.714
2013 Elsworth JD, Redmond DE, Roth RH. Coordinated expression of dopamine transporter and vesicular monoamine transporter in the primate striatum during development. Synapse (New York, N.Y.). 67: 580-5. PMID 23468413 DOI: 10.1002/Syn.21662  0.755
2013 Elsworth JD, Jentsch JD, Vandevoort CA, Roth RH, Jr DE, Leranth C. Prenatal exposure to bisphenol A impacts midbrain dopamine neurons and hippocampal spine synapses in non-human primates. Neurotoxicology. 35: 113-20. PMID 23337607 DOI: 10.1016/J.Neuro.2013.01.001  0.735
2013 Elsworth JD, Leranth C, Redmond DE, Roth RH. Loss of asymmetric spine synapses in prefrontal cortex of motor-asymptomatic, dopamine-depleted, cognitively impaired MPTP-treated monkeys. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 905-12. PMID 22947206 DOI: 10.1017/S1461145712000892  0.724
2012 Morrow BA, Roth RH, Redmond DE, Diano S, Elsworth JD. Susceptibility to a parkinsonian toxin varies during primate development. Experimental Neurology. 235: 273-81. PMID 22366325 DOI: 10.1016/J.Expneurol.2012.02.005  0.741
2012 Miller BH, Zeier Z, Xi L, Lanz TA, Deng S, Strathmann J, Willoughby D, Kenny PJ, Elsworth JD, Lawrence MS, Roth RH, Edbauer D, Kleiman RJ, Wahlestedt C. MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proceedings of the National Academy of Sciences of the United States of America. 109: 3125-30. PMID 22315408 DOI: 10.1073/Pnas.1113793109  0.644
2012 Elsworth JD, Groman SM, Jentsch JD, Valles R, Shahid M, Wong E, Marston H, Roth RH. Asenapine effects on cognitive and monoamine dysfunction elicited by subchronic phencyclidine administration. Neuropharmacology. 62: 1442-52. PMID 21875607 DOI: 10.1016/J.Neuropharm.2011.08.026  0.827
2011 Elsworth JD, Hajszan T, Leranth C, Roth RH. Loss of asymmetric spine synapses in dorsolateral prefrontal cortex of cognitively impaired phencyclidine-treated monkeys. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1411-5. PMID 21733230 DOI: 10.1017/S1461145711000939  0.663
2011 Abizaid A, Mineur YS, Roth RH, Elsworth JD, Sleeman MW, Picciotto MR, Horvath TL. Reduced locomotor responses to cocaine in ghrelin-deficient mice. Neuroscience. 192: 500-6. PMID 21699961 DOI: 10.1016/J.Neuroscience.2011.06.001  0.722
2011 Elsworth JD, Morrow BA, Hajszan T, Leranth C, Roth RH. Phencyclidine-induced loss of asymmetric spine synapses in rodent prefrontal cortex is reversed by acute and chronic treatment with olanzapine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2054-61. PMID 21677652 DOI: 10.1038/Npp.2011.96  0.675
2011 Morrow BA, Roth RH, Redmond DE, Elsworth JD. Impact of methamphetamine on dopamine neurons in primates is dependent on age: implications for development of Parkinson's disease. Neuroscience. 189: 277-85. PMID 21640165 DOI: 10.1016/J.Neuroscience.2011.05.046  0.754
2011 Hurley PJ, Elsworth JD, Whittaker MC, Roth RH, Redmond DE. Aged monkeys as a partial model for Parkinson's disease. Pharmacology, Biochemistry, and Behavior. 99: 324-32. PMID 21620883 DOI: 10.1016/J.Pbb.2011.05.007  0.708
2011 Horvath TL, Erion DM, Elsworth JD, Roth RH, Shulman GI, Andrews ZB. GPA protects the nigrostriatal dopamine system by enhancing mitochondrial function. Neurobiology of Disease. 43: 152-62. PMID 21406233 DOI: 10.1016/J.Nbd.2011.03.005  0.677
2010 Redmond DE, Weiss S, Elsworth JD, Roth RH, Wakeman DR, Bjugstad KB, Collier TJ, Blanchard BC, Teng YD, Synder EY, Sladek JR. Cellular repair in the parkinsonian nonhuman primate brain. Rejuvenation Research. 13: 188-94. PMID 20370501 DOI: 10.1089/Rej.2009.0960  0.721
2010 Markakis EA, Vives KP, Bober J, Leichtle S, Leranth C, Beecham J, Elsworth JD, Roth RH, Samulski RJ, Redmond DE. Comparative transduction efficiency of AAV vector serotypes 1-6 in the substantia nigra and striatum of the primate brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 588-93. PMID 20010918 DOI: 10.1038/Mt.2009.286  0.667
2009 Andrews ZB, Erion D, Beiler R, Liu ZW, Abizaid A, Zigman J, Elsworth JD, Savitt JM, DiMarchi R, Tschoep M, Roth RH, Gao XB, Horvath TL. Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14057-65. PMID 19906954 DOI: 10.1523/Jneurosci.3890-09.2009  0.744
2009 Redmond DE, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P, Sladek JR. Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF. The Journal of Comparative Neurology. 515: 31-40. PMID 19399891 DOI: 10.1002/Cne.22028  0.71
2008 Jentsch JD, Sanchez D, Elsworth JD, Roth RH. Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype. Brain Research. 1246: 41-6. PMID 18977208 DOI: 10.1016/J.Brainres.2008.10.006  0.726
2008 Sladek JR, Bjugstad KB, Collier TJ, Bundock EA, Blanchard BC, Elsworth JD, Roth RH, Redmond DE. Embryonic substantia nigra grafts show directional outgrowth to cografted striatal grafts and potential for pathway reconstruction in nonhuman primate. Cell Transplantation. 17: 427-44. PMID 18522245 DOI: 10.3727/096368908784423274  0.696
2008 Bjugstad KB, Teng YD, Redmond DE, Elsworth JD, Roth RH, Cornelius SK, Snyder EY, Sladek JR. Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease. Experimental Neurology. 211: 362-9. PMID 18394605 DOI: 10.1016/J.Expneurol.2008.01.025  0.689
2008 Elsworth JD, Redmond DE, Leranth C, Bjugstad KB, Sladek JR, Collier TJ, Foti SB, Samulski RJ, Vives KP, Roth RH. AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons. Experimental Neurology. 211: 252-8. PMID 18346734 DOI: 10.1016/J.Expneurol.2008.01.026  0.743
2008 Elsworth JD, Jentsch JD, Morrow BA, Redmond DE, Roth RH. Clozapine normalizes prefrontal cortex dopamine transmission in monkeys subchronically exposed to phencyclidine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 491-6. PMID 17507917 DOI: 10.1038/Sj.Npp.1301448  0.734
2008 Elsworth JD, Morrow BA, Nguyen VT, Mitra J, Picciotto MR, Roth RH. Corrigendum to "prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: Role of autoreceptors". [Neuroscience 147 (2007) 419-427] (DOI:10.1016/j.neuroscience.2007.04.036) Neuroscience. 156: 800. DOI: 10.1016/J.Neuroscience.2008.08.024  0.737
2007 Morrow BA, Hajszan T, Leranth C, Elsworth JD, Roth RH. Prenatal exposure to cocaine is associated with increased number of spine synapses in rat prelimbic cortex. Synapse (New York, N.Y.). 61: 862-5. PMID 17630673 DOI: 10.1002/Syn.20430  0.689
2007 Redmond DE, Bjugstad KB, Teng YD, Ourednik V, Ourednik J, Wakeman DR, Parsons XH, Gonzalez R, Blanchard BC, Kim SU, Gu Z, Lipton SA, Markakis EA, Roth RH, Elsworth JD, et al. Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 12175-80. PMID 17586681 DOI: 10.1073/Pnas.0704091104  0.726
2007 Elsworth JD, Morrow BA, Nguyen VT, Mitra J, Picciotto MR, Roth RH. Prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: role of autoreceptors. Neuroscience. 147: 419-27. PMID 17543464 DOI: 10.1016/J.Neuroscience.2007.04.036  0.754
2007 Morrow BA, Roth RH, Redmond DE, Sladek JR, Elsworth JD. Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation. Experimental Neurology. 204: 802-7. PMID 17313945 DOI: 10.1016/J.Expneurol.2007.01.009  0.748
2007 Morrow BA, Elsworth JD, Roth RH. Repeated phencyclidine in monkeys results in loss of parvalbumin-containing axo-axonic projections in the prefrontal cortex. Psychopharmacology. 192: 283-90. PMID 17265073 DOI: 10.1007/S00213-007-0708-0  0.681
2006 Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, Tschöp MH, Gao XB, Horvath TL. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. The Journal of Clinical Investigation. 116: 3229-39. PMID 17060947 DOI: 10.1172/Jci29867  0.734
2006 Andrews ZB, Rivera A, Elsworth JD, Roth RH, Agnati L, Gago B, Abizaid A, Schwartz M, Fuxe K, Horvath TL. Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function. The European Journal of Neuroscience. 24: 32-6. PMID 16882005 DOI: 10.1111/J.1460-9568.2006.04906.X  0.748
2006 Hajszan T, Leranth C, Roth RH. Subchronic phencyclidine treatment decreases the number of dendritic spine synapses in the rat prefrontal cortex. Biological Psychiatry. 60: 639-44. PMID 16814748 DOI: 10.1016/J.Biopsych.2006.03.015  0.323
2005 Bjugstad KB, Redmond DE, Teng YD, Elsworth JD, Roth RH, Blanchard BC, Snyder EY, Sladek JR. Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures. Cell Transplantation. 14: 183-92. PMID 15929553 DOI: 10.3727/000000005783983098  0.69
2005 Morrow BA, Redmond DE, Roth RH, Elsworth JD. Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey. The Journal of Comparative Neurology. 488: 215-23. PMID 15924344 DOI: 10.1002/Cne.20599  0.733
2005 Marrs W, Kuperman J, Avedian T, Roth RH, Jentsch JD. Alpha-2 adrenoceptor activation inhibits phencyclidine-induced deficits of spatial working memory in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1500-10. PMID 15714223 DOI: 10.1038/Sj.Npp.1300700  0.307
2005 Morrow BA, Elsworth JD, Roth RH. Prenatal exposure to cocaine selectively disrupts the development of parvalbumin containing local circuit neurons in the medial prefrontal cortex of the rat. Synapse (New York, N.Y.). 56: 1-11. PMID 15700288 DOI: 10.1002/Syn.20121  0.701
2005 Andrews ZB, Horvath B, Barnstable CJ, Elsworth J, Elseworth J, Yang L, Beal MF, Roth RH, Matthews RT, Horvath TL. Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 184-91. PMID 15634780 DOI: 10.1523/Jneurosci.4269-04.2005  0.727
2004 Morrow BA, George TP, Roth RH. Noradrenergic alpha-2 agonists have anxiolytic-like actions on stress-related behavior and mesoprefrontal dopamine biochemistry. Brain Research. 1027: 173-8. PMID 15494168 DOI: 10.1016/J.Brainres.2004.08.057  0.478
2004 Verrico CD, Jentsch JD, Roth RH, Taylor JR. Repeated, intermittent delta(9)-tetrahydrocannabinol administration to rats impairs acquisition and performance of a test of visuospatial divided attention. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 522-9. PMID 14694348 DOI: 10.1038/Sj.Npp.1300316  0.653
2003 Morrow BA, Elsworth JD, Roth RH. Axo-axonic structures in the medial prefrontal cortex of the rat: reduction by prenatal exposure to cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5227-34. PMID 12832547 DOI: 10.1523/Jneurosci.23-12-05227.2003  0.691
2003 Horvath TL, Diano S, Leranth C, Garcia-Segura LM, Cowley MA, Shanabrough M, Elsworth JD, Sotonyi P, Roth RH, Dietrich EH, Matthews RT, Barnstable CJ, Redmond DE. Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease. Endocrinology. 144: 2757-60. PMID 12810526 DOI: 10.1210/En.2003-0163  0.717
2003 Verrico CD, Jentsch JD, Roth RH. Persistent and anatomically selective reduction in prefrontal cortical dopamine metabolism after repeated, intermittent cannabinoid administration to rats. Synapse (New York, N.Y.). 49: 61-6. PMID 12710016 DOI: 10.1002/Syn.10215  0.739
2003 Verrico CD, Jentsch JD, Dazzi L, Roth RH. Systemic, but not local, administration of cannabinoid CB1 receptor agonists modulate prefrontal cortical acetylcholine efflux in the rat. Synapse (New York, N.Y.). 48: 178-83. PMID 12687636 DOI: 10.1002/Syn.10202  0.689
2002 De La Garza R, Jentsch JD, Verrico CD, Roth RH. Adaptation of monoaminergic responses to phencyclidine in nucleus accumbens and prefrontal cortex following repeated treatment with fluoxetine or imipramine. Brain Research. 958: 20-7. PMID 12468026 DOI: 10.1016/S0006-8993(02)03772-1  0.715
2002 Morrow BA, Elsworth JD, Roth RH. Fear-like biochemical and behavioral responses in rats to the predator odor, TMT, are dependent on the exposure environment. Synapse (New York, N.Y.). 46: 11-8. PMID 12211094 DOI: 10.1002/Syn.10109  0.698
2002 Redmond AJ, Morrow BA, Elsworth JD, Roth RH. Selective activation of the A10, but not A9, dopamine neurons in the rat by the predator odor, 2,5-dihydro-2,4,5-trimethylthiazoline. Neuroscience Letters. 328: 209-12. PMID 12147308 DOI: 10.1016/S0304-3940(02)00566-9  0.703
2002 Morrow BA, Elsworth JD, Roth RH. Male rats exposed to cocaine in utero demonstrate elevated expression of Fos in the prefrontal cortex in response to environment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 275-85. PMID 11850142 DOI: 10.1016/S0893-133X(01)00359-1  0.7
2002 Morrow BA, Elsworth JD, Roth RH. Prenatal cocaine exposure disrupts non-spatial, short-term memory in adolescent and adult male rats. Behavioural Brain Research. 129: 217-23. PMID 11809514 DOI: 10.1016/S0166-4328(01)00338-2  0.675
2002 Collier TJ, Sortwell CE, Elsworth JD, Taylor JR, Roth RH, Sladek JR, Redmond DE. Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease. The Journal of Comparative Neurology. 442: 320-30. PMID 11793337 DOI: 10.1002/Cne.10108  0.726
2002 Jentsch J, Roth R, Taylor J, Verrico C. Cannabinoid effects on neurocognition: Implications for psychosis European Neuropsychopharmacology. 12: 130-131. DOI: 10.1016/S0924-977X(02)80071-2  0.637
2001 Elsworth JD, Morrow BA, Roth RH. Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress. Synapse (New York, N.Y.). 42: 80-3. PMID 11574943 DOI: 10.1002/Syn.1102  0.736
2001 Morrow BA, Elsworth JD, Roth RH. Prenatal exposure to cocaine reduces the number and enhances reactivity of A10 dopaminergic neurons to environmental stress. Synapse (New York, N.Y.). 41: 337-44. PMID 11494404 DOI: 10.1002/Syn.1090  0.72
2001 Zachariou V, Caldarone BJ, Weathers-Lowin A, George TP, Elsworth JD, Roth RH, Changeux JP, Picciotto MR. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 576-89. PMID 11282258 DOI: 10.1016/S0893-133X(00)00224-4  0.695
2001 George TP, Picciotto MR, Verrico CD, Roth RH. Effects of nicotine pretreatment on dopaminergic and behavioral responses to conditioned fear stress in rats: dissociation of biochemical and behavioral effects. Biological Psychiatry. 49: 300-6. PMID 11230881 DOI: 10.1016/S0006-3223(00)00928-8  0.677
2000 Jentsch JD, Roth RH, Taylor JR. Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: implications for mental disorders and psychotropic drug action. Progress in Brain Research. 126: 433-53. PMID 11105661 DOI: 10.1016/S0079-6123(00)26028-7  0.364
2000 Leranth C, Roth RH, Elsworth JD, Naftolin F, Horvath TL, Redmond DE. Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8604-9. PMID 11102464 DOI: 10.1523/Jneurosci.20-23-08604.2000  0.73
2000 George TP, Verrico CD, Picciotto MR, Roth RH. Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization. The Journal of Pharmacology and Experimental Therapeutics. 295: 58-66. PMID 10991961  0.675
2000 Jentsch JD, Roth RH, Taylor JR. Object retrieval/detour deficits in monkeys produced by prior subchronic phencyclidine administration: evidence for cognitive impulsivity. Biological Psychiatry. 48: 415-24. PMID 10978725 DOI: 10.1016/S0006-3223(00)00926-4  0.341
2000 Morrow BA, Roth RH, Elsworth JD. TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat. Brain Research Bulletin. 52: 519-23. PMID 10974491 DOI: 10.1016/S0361-9230(00)00290-2  0.702
2000 George TP, Verrico CD, Xu L, Roth RH. Effects of repeated nicotine administration and footshock stress on rat mesoprefrontal dopamine systems: Evidence for opioid mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 79-88. PMID 10869888 DOI: 10.1016/S0893-133X(99)00165-7  0.684
2000 Morrow BA, Redmond AJ, Roth RH, Elsworth JD. The predator odor, TMT, displays a unique, stress-like pattern of dopaminergic and endocrinological activation in the rat. Brain Research. 864: 146-51. PMID 10793199 DOI: 10.1016/S0006-8993(00)02174-0  0.7
2000 Morrow BA, Elsworth JD, Lee EJ, Roth RH. Divergent effects of putative anxiolytics on stress-induced fos expression in the mesoprefrontal system of the rat. Synapse (New York, N.Y.). 36: 143-54. PMID 10767061 DOI: 10.1002/(Sici)1098-2396(200005)36:2<143::Aid-Syn7>3.0.Co;2-H  0.713
2000 Elsworth JD, Taylor JR, Sladek JR, Collier TJ, Redmond DE, Roth RH. Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment. Neuroscience. 95: 399-408. PMID 10658619 DOI: 10.1016/S0306-4522(99)00437-6  0.76
2000 Jentsch JD, Taylor JR, Roth RH. Phencyclidine Model of Frontal Cortical Dysfunction in Nonhuman Primates The Neuroscientist. 6: 263-270. DOI: 10.1177/107385840000600409  0.327
2000 Jentsch J, Grace A, Roth R. NMDA receptor hypofunction and animal models of schizophrenia European Neuropsychopharmacology. 10: 209-210. DOI: 10.1016/S0924-977X(00)80122-4  0.429
1999 Morrow BA, Rosenberg SJ, Roth RH. Chronic clozapine, but not haloperidol, alters the response of mesoprefrontal dopamine neurons to stress and clozapine challenges in rats. Synapse (New York, N.Y.). 34: 28-35. PMID 10459169 DOI: 10.1002/(SICI)1098-2396(199910)34:1<28::AID-SYN4>3.0.CO;2-E  0.485
1999 Taylor JR, Elsworth JD, Lawrence MS, Sladek JR, Roth RH, Redmond DE. Spontaneous blink rates correlate with dopamine levels in the caudate nucleus of MPTP-treated monkeys. Experimental Neurology. 158: 214-20. PMID 10448434 DOI: 10.1006/Exnr.1999.7093  0.726
1999 Morrow BA, Elsworth JD, Rasmusson AM, Roth RH. The role of mesoprefrontal dopamine neurons in the acquisition and expression of conditioned fear in the rat. Neuroscience. 92: 553-64. PMID 10408604 DOI: 10.1016/S0306-4522(99)00014-7  0.718
1999 Morrow BA, Elsworth JD, Inglis FM, Roth RH. An antisense oligonucleotide reverses the footshock-induced expression of fos in the rat medial prefrontal cortex and the subsequent expression of conditioned fear-induced immobility. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5666-73. PMID 10377372 DOI: 10.1523/Jneurosci.19-13-05666.1999  0.678
1999 Morrow BA, Elsworth JD, Zito C, Roth RH. Biochemical and behavioral anxiolytic-like effects of R(+)HA-966 at the level of the ventral tegmental area in rats. Psychopharmacology. 143: 227-34. PMID 10353424 DOI: 10.1007/S002130050941  0.709
1999 Berridge CW, Mitton E, Clark W, Roth RH. Engagement in a non-escape (displacement) behavior elicits a selective and lateralized suppression of frontal cortical dopaminergic utilization in stress. Synapse (New York, N.Y.). 32: 187-97. PMID 10340629 DOI: 10.1002/(Sici)1098-2396(19990601)32:3<187::Aid-Syn5>3.0.Co;2-9  0.429
1999 Jentsch JD, Taylor JR, Elsworth JD, Redmond DE, Roth RH. Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits. Neuroscience. 90: 823-32. PMID 10218783 DOI: 10.1016/S0306-4522(98)00481-3  0.726
1999 Youngren KD, Inglis FM, Pivirotto PJ, Jedema HP, Bradberry CW, Goldman-Rakic PS, Roth RH, Moghaddam B. Clozapine preferentially increases dopamine release in the rhesus monkey prefrontal cortex compared with the caudate nucleus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 403-12. PMID 10192821 DOI: 10.1016/S0893-133X(98)00082-7  0.84
1999 Jentsch JD, Taylor JR, Redmond DE, Elsworth JD, Youngren KD, Roth RH. Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys. Psychopharmacology. 142: 78-84. PMID 10102786 DOI: 10.1007/S002130050865  0.707
1999 Abi-Saab WM, Bubser M, Roth RH, Deutch AY. 5-HT2 receptor regulation of extracellular GABA levels in the prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 92-6. PMID 9885788 DOI: 10.1016/S0893-133X(98)00046-3  0.634
1998 Jentsch JD, Dazzi L, Chhatwal JP, Verrico CD, Roth RH. Reduced prefrontal cortical dopamine, but not acetylcholine, release in vivo after repeated, intermittent phencyclidine administration to rats. Neuroscience Letters. 258: 175-8. PMID 9885959 DOI: 10.1016/S0304-3940(98)00879-9  0.783
1998 Leranth C, Sladek JR, Roth RH, Redmond DE. Efferent synaptic connections of dopaminergic neurons grafted into the caudate nucleus of experimentally induced parkinsonian monkeys are different from those of control animals. Experimental Brain Research. 123: 323-33. PMID 9860271 DOI: 10.1007/S002210050575  0.425
1998 Jentsch JD, Verrico CD, Le D, Roth RH. Repeated exposure to delta 9-tetrahydrocannabinol reduces prefrontal cortical dopamine metabolism in the rat. Neuroscience Letters. 246: 169-72. PMID 9792619 DOI: 10.1016/S0304-3940(98)00254-7  0.721
1998 During MJ, Samulski RJ, Elsworth JD, Kaplitt MG, Leone P, Xiao X, Li J, Freese A, Taylor JR, Roth RH, Sladek JR, O'Malley KL, Redmond DE. In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector. Gene Therapy. 5: 820-7. PMID 9747462 DOI: 10.1038/Sj.Gt.3300650  0.777
1998 George TP, Verrico CD, Roth RH. Effects of repeated nicotine pre-treatment on mesoprefrontal dopaminergic and behavioral responses to acute footshock stress. Brain Research. 801: 36-49. PMID 9729261 DOI: 10.1016/S0006-8993(98)00537-X  0.672
1998 Jentsch JD, Tran A, Taylor JR, Roth RH. Prefrontal cortical involvement in phencyclidine-induced activation of the mesolimbic dopamine system: behavioral and neurochemical evidence. Psychopharmacology. 138: 89-95. PMID 9694531 DOI: 10.1007/s002130050649  0.502
1998 Jentsch JD, Taylor JR, Roth RH. Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant-induced hyperlocomotion. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 105-13. PMID 9629564 DOI: 10.1016/S0893-133X(98)00004-9  0.472
1998 Elsworth JD, Brittan MS, Taylor JR, Sladek JR, Redmond DE, Innis RB, Zea-Ponce Y, Roth RH. Upregulation of striatal D2 receptors in the MPTP-treated vervet monkey is reversed by grafts of fetal ventral mesencephalon: an autoradiographic study. Brain Research. 795: 55-62. PMID 9622593 DOI: 10.1016/S0006-8993(98)00252-2  0.757
1998 Sortwell CE, Blanchard BC, Collier TJ, Elsworth JD, Taylor JR, Roth RH, Redmond DE, Sladek JR. Pattern of synaptophysin immunoreactivity within mesencephalic grafts following transplantation in a parkinsonian primate model. Brain Research. 791: 117-24. PMID 9593853 DOI: 10.1016/S0006-8993(98)00086-9  0.688
1998 Sladek JR, Collier TJ, Elsworth JD, Roth RH, Taylor JR, Redmond DE. Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in nonhuman primates. Cell Transplantation. 7: 87-96. PMID 9588591 DOI: 10.1016/S0963-6897(98)00007-4  0.716
1998 Jentsch JD, Wise A, Katz Z, Roth RH. Alpha-noradrenergic receptor modulation of the phencyclidine- and delta9-tetrahydrocannabinol-induced increases in dopamine utilization in rat prefrontal cortex. Synapse (New York, N.Y.). 28: 21-6. PMID 9414014 DOI: 10.1002/(SICI)1098-2396(199801)28:1<21::AID-SYN3>3.0.CO;2-E  0.459
1998 Jentsch JD, Elsworth JD, Taylor JR, Redmond DE, Roth RH. Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia. Advances in Pharmacology (San Diego, Calif.). 42: 810-4. PMID 9328021 DOI: 10.1016/S1054-3589(08)60870-4  0.7
1997 Morrow BA, Lee EJ, Taylor JR, Elsworth JD, Nye HE, Roth RH. (S)-(-)-HA-966, a gamma-hydroxybutyrate-like agent, prevents enhanced mesocorticolimbic dopamine metabolism and behavioral correlates of restraint stress, conditioned fear and cocaine sensitization. The Journal of Pharmacology and Experimental Therapeutics. 283: 712-21. PMID 9353390  0.701
1997 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Redmond DE. Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus). Neuroscience. 81: 745-55. PMID 9316026 DOI: 10.1016/S0306-4522(97)00214-5  0.688
1997 Jentsch JD, Redmond DE, Elsworth JD, Taylor JR, Youngren KD, Roth RH. Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine. Science (New York, N.Y.). 277: 953-5. PMID 9252326 DOI: 10.1126/Science.277.5328.953  0.735
1997 Alexander T, Sortwell CE, Sladek CD, Roth RH, Steece-Collier K. Comparison of neurotoxicity following repeated administration of l-dopa, d-dopa and dopamine to embryonic mesencephalic dopamine neurons in cultures derived from Fisher 344 and Sprague-Dawley donors. Cell Transplantation. 6: 309-15. PMID 9171163 DOI: 10.1016/S0963-6897(97)00031-6  0.335
1997 Murphy BL, Roth RH, Arnsten AF. Clozapine reverses the spatial working memory deficits induced by FG7142 in monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 433-7. PMID 9165499 DOI: 10.1016/S0893-133X(97)00019-5  0.339
1997 Jentsch JD, Andrusiak E, Tran A, Bowers MB, Roth RH. Delta 9-tetrahydrocannabinol increases prefrontal cortical catecholaminergic utilization and impairs spatial working memory in the rat: blockade of dopaminergic effects with HA966. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 16: 426-32. PMID 9165498 DOI: 10.1016/S0893-133X(97)00018-3  0.418
1997 Collier TJ, Redmond DE, Roth RH, Elsworth JD, Taylor JR, Sladek JR. Metabolic energy capacity of dopaminergic grafts and the implanted striatum in parkinsonian nonhuman primates as visualized with cytochrome oxidase histochemistry. Cell Transplantation. 6: 135-40. PMID 9142445 DOI: 10.1016/S0963-6897(97)00003-1  0.713
1997 Elsworth JD, Roth RH. Dopamine synthesis, uptake, metabolism, and receptors: relevance to gene therapy of Parkinson's disease. Experimental Neurology. 144: 4-9. PMID 9126143 DOI: 10.1006/Exnr.1996.6379  0.73
1997 Tam SY, Roth RH. Mesoprefrontal dopaminergic neurons: can tyrosine availability influence their functions? Biochemical Pharmacology. 53: 441-53. PMID 9105394 DOI: 10.1016/S0006-2952(96)00774-5  0.444
1997 Jentsch JD, Elsworth JD, Redmond DE, Roth RH. Phencyclidine increases forebrain monoamine metabolism in rats and monkeys: modulation by the isomers of HA966. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1769-75. PMID 9030635 DOI: 10.1523/Jneurosci.17-05-01769.1997  0.754
1997 Tam SY, Elsworth JD, Sladek JR, Redmond DE, Roth RH. Identification of novel variants of trkC mRNA transcripts in brain of African green monkeys. Experimental Neurology. 143: 172-6. PMID 9000456 DOI: 10.1006/Exnr.1996.6338  0.663
1997 Young CD, Roth RH, Deutch AY. The neurotensin agonist PD 149163 induces Fos protein expression in the prefrontal cortex: Similarities to atypical antipsychotic drugs Schizophrenia Research. 24: 84. DOI: 10.1016/S0920-9964(97)82228-1  0.577
1996 Horger BA, Roth RH. The role of mesoprefrontal dopamine neurons in stress. Critical Reviews in Neurobiology. 10: 395-418. PMID 8978988 DOI: 10.1615/Critrevneurobiol.V10.I3-4.60  0.421
1996 Murphy BL, Arnsten AF, Jentsch JD, Roth RH. Dopamine and spatial working memory in rats and monkeys: pharmacological reversal of stress-induced impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7768-75. PMID 8922432  0.402
1996 Horger BA, Taylor JR, Elsworth JD, Jatlow PI, Roth RH. Sensitization to the locomotor activating effects of cocaine following cocaethylene-preexposure. Brain Research. 733: 133-7. PMID 8891259 DOI: 10.1016/0006-8993(96)00783-4  0.685
1996 Jatlow P, McCance EF, Bradberry CW, Elsworth JD, Taylor JR, Roth RH. Alcohol plus cocaine: the whole is more than the sum of its parts. Therapeutic Drug Monitoring. 18: 460-4. PMID 8857569 DOI: 10.1097/00007691-199608000-00026  0.774
1996 Deutch AY, Lewis DA, Whitehead RE, Elsworth JD, Iadarola MJ, Redmond DE, Roth RH. Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate. Synapse (New York, N.Y.). 23: 182-91. PMID 8807746 DOI: 10.1002/(Sici)1098-2396(199607)23:3<182::Aid-Syn7>3.0.Co;2-4  0.804
1996 Morrow BA, Roth RH. Serotonergic lesions alter cocaine-induced locomotor behavior and stress-activation of the mesocorticolimbic dopamine system. Synapse (New York, N.Y.). 23: 174-81. PMID 8807745 DOI: 10.1002/(SICI)1098-2396(199607)23:3<174::AID-SYN6>3.0.CO;2-5  0.448
1996 Morrow BA, Elsworth JD, Roth RH. Tyrosine enhances behavioral and mesocorticolimbic dopaminergic responses to aversive conditioning. Synapse (New York, N.Y.). 22: 100-5. PMID 8787125 DOI: 10.1002/(Sici)1098-2396(199602)22:2<100::Aid-Syn2>3.0.Co;2-H  0.756
1996 Horger BA, Elsworth JD, Roth RH. Blockade of FG 7142-induced increased dopamine utilization by the glycine/NMDA receptor antagonist (+)-HA 966. Journal of Neurochemistry. 66: 1959-62. PMID 8780023 DOI: 10.1046/J.1471-4159.1996.66051959.X  0.754
1996 Goldstein LE, Rasmusson AM, Bunney BS, Roth RH. Role of the amygdala in the coordination of behavioral, neuroendocrine, and prefrontal cortical monoamine responses to psychological stress in the rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4787-98. PMID 8764665 DOI: 10.1523/Jneurosci.16-15-04787.1996  0.326
1996 Elsworth JD, Sladek JR, Taylor JR, Collier TJ, Redmond DE, Roth RH. Early gestational mesencephalon grafts, but not later gestational mesencephalon, cerebellum or sham grafts, increase dopamine in caudate nucleus of MPTP-treated monkeys. Neuroscience. 72: 477-84. PMID 8737417 DOI: 10.1016/0306-4522(95)00564-1  0.744
1996 Elsworth JD, Brittan MS, Taylor JR, Sladek JR, al-Tikriti MS, Zea-Ponce Y, Innis RB, Redmond DE, Roth RH. Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys. Cell Transplantation. 5: 315-25. PMID 8689042 DOI: 10.1016/0963-6897(95)02034-9  0.756
1996 Murphy BL, Arnsten AF, Goldman-Rakic PS, Roth RH. Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proceedings of the National Academy of Sciences of the United States of America. 93: 1325-9. PMID 8577763 DOI: 10.1073/pnas.93.3.1325  0.344
1995 Abarca J, Gysling K, Roth RH, Bustos G. Changes in extracellular levels of glutamate and aspartate in rat substantia nigra induced by dopamine receptor ligands: in vivo microdialysis studies. Neurochemical Research. 20: 159-69. PMID 7783840 DOI: 10.1007/BF00970540  0.382
1995 Rosin DL, Melia K, Knorr AM, Nestler EJ, Roth RH, Duman RS. Chronic imipramine administration alters the activity and phosphorylation state of tyrosine hydroxylase in dopaminergic regions of rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 12: 113-21. PMID 7779239 DOI: 10.1016/0893-133X(94)00066-9  0.394
1995 Morrow BA, Taylor JR, Roth RH. R-(+)-HA-966, an antagonist for the glycine/NMDA receptor, prevents locomotor sensitization to repeated cocaine exposures. Brain Research. 673: 165-9. PMID 7757472 DOI: 10.1016/0006-8993(94)01456-R  0.315
1995 Taylor JR, Elsworth JD, Sladek JR, Collier TJ, Roth RH, Redmond DE. Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys. Cell Transplantation. 4: 13-26. PMID 7728327 DOI: 10.1016/0963-6897(94)00035-I  0.747
1995 Horger BA, Elsworth JD, Roth RH. Selective increase in dopamine utilization in the shell subdivision of the nucleus accumbens by the benzodiazepine inverse agonist FG 7142. Journal of Neurochemistry. 65: 770-4. PMID 7616234 DOI: 10.1046/J.1471-4159.1995.65020770.X  0.759
1994 Youngren KD, Moghaddam B, Bunney BS, Roth RH. Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment. Neuroscience Letters. 165: 41-4. PMID 8015734 DOI: 10.1016/0304-3940(94)90704-8  0.49
1994 Iyer RN, Sprouse JS, Aghajanian GK, Roth RH, Bradberry CW. Tryptophan pretreatment augmentation of p-chloroamphetamine-induced serotonin and dopamine release and reduction of long-term neurotoxicity. Biochemical Pharmacology. 48: 1501-8. PMID 7945451 DOI: 10.1016/0006-2952(94)90576-2  0.724
1994 Elsworth JD, al-Tikriti MS, Sladek JR, Taylor JR, Innis RB, Redmond DE, Roth RH. Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function. Experimental Neurology. 126: 300-4. PMID 7925828 DOI: 10.1006/Exnr.1994.1068  0.735
1994 Davis M, Hitchcock JM, Bowers MB, Berridge CW, Melia KR, Roth RH. Stress-induced activation of prefrontal cortex dopamine turnover: blockade by lesions of the amygdala. Brain Research. 664: 207-10. PMID 7895029 DOI: 10.1016/0006-8993(94)91972-0  0.446
1994 Horger BA, Taylor JR, Elsworth JD, Roth RH. Preexposure to, but not cotreatment with, the neurotensin antagonist SR 48692 delays the development of cocaine sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 11: 215-22. PMID 7865101 DOI: 10.1038/Sj.Npp.1380108  0.675
1994 Rasmusson AM, Goldstein LE, Deutch AY, Bunney BS, Roth RH. 5-HT1a agonist +/-8-OH-DPAT modulates basal and stress-induced changes in medial prefrontal cortical dopamine. Synapse (New York, N.Y.). 18: 218-24. PMID 7855734 DOI: 10.1002/Syn.890180307  0.695
1994 Collier TJ, Elsworth JD, Taylor JR, Sladek JR, Roth RH, Redmond DE. Peripheral nerve-dopamine neuron co-grafts in MPTP-treated monkeys: augmentation of tyrosine hydroxylase-positive fiber staining and dopamine content in host systems. Neuroscience. 61: 875-89. PMID 7838385 DOI: 10.1016/0306-4522(94)90410-3  0.724
1994 Tam S, Elsworth JD, Redmond DE, Roth RH. Expression Of A Novel TRK C Receptor Isoform With Truncated Extracellular Domain In Fetal And Adult Monkey Brains Neuropsychopharmacology. 11: 286-286. DOI: 10.1038/Sj.Npp.1380219  0.653
1993 Moghaddam B, Berridge CW, Goldman-Rakic PS, Bunney BS, Roth RH. In vivo assessment of basal and drug-induced dopamine release in cortical and subcortical regions of the anesthetized primate. Synapse (New York, N.Y.). 13: 215-22. PMID 8497807 DOI: 10.1002/Syn.890130304  0.48
1993 Bradberry CW, Nobiletti JB, Elsworth JD, Murphy B, Jatlow P, Roth RH. Cocaine and cocaethylene: microdialysis comparison of brain drug levels and effects on dopamine and serotonin. Journal of Neurochemistry. 60: 1429-35. PMID 8455033 DOI: 10.1111/J.1471-4159.1993.Tb03305.X  0.787
1993 Morrow BA, Clark WA, Roth RH. Stress activation of mesocorticolimbic dopamine neurons: effects of a glycine/NMDA receptor antagonist. European Journal of Pharmacology. 238: 255-62. PMID 8405096 DOI: 10.1016/0014-2999(93)90855-C  0.469
1993 Elsworth JD, Taylor JR, Berger P, Roth RH. Cocaine-sensitive and -insensitive dopamine uptake in prefrontal cortex, nucleus accumbens and striatum. Neurochemistry International. 23: 61-9. PMID 8369733 DOI: 10.1016/0197-0186(93)90144-T  0.722
1993 Sladek JR, Collier TJ, Elsworth JD, Taylor JR, Roth RH, Redmond DE. Can graft-derived neurotrophic activity be used to direct axonal outgrowth of grafted dopamine neurons for circuit reconstruction in primates? Experimental Neurology. 124: 134-9. PMID 8282070 DOI: 10.1006/exnr.1993.1184  0.671
1993 Redmond DE, Roth RH, Spencer DD, Naftolin F, Leranth C, Robbins RJ, Marek KL, Elsworth JD, Taylor JR, Sass KJ. Neural transplantation for neurodegenerative diseases: past, present, and future. Annals of the New York Academy of Sciences. 695: 258-66. PMID 8239293 DOI: 10.1111/J.1749-6632.1993.Tb23064.X  0.717
1993 Sladek JR, Elsworth JD, Roth RH, Evans LE, Collier TJ, Cooper SJ, Taylor JR, Redmond DE. Fetal dopamine cell survival after transplantation is dramatically improved at a critical donor gestational age in nonhuman primates. Experimental Neurology. 122: 16-27. PMID 8101820 DOI: 10.1006/exnr.1993.1103  0.713
1993 Kontur PJ, Leranth C, Redmond DE, Roth RH, Robbins RJ. Tyrosine hydroxylase immunoreactivity and monoamine and metabolite levels in cryopreserved human fetal ventral mesencephalon. Experimental Neurology. 121: 172-80. PMID 7687960 DOI: 10.1006/exnr.1993.1084  0.407
1993 Elsworth JD, Taylor JR, Jatlow P, Roth RH. Serotonin involvement in cocaine sensitization: Clues from studies with cocaine analogs Drug Development Research. 30: 189-200. DOI: 10.1002/Ddr.430300311  0.702
1993 Spencer DD, Robbins RJ, Naftolin F, Marek KL, Vollmer T, Leranth C, Roth RH, Price LH, Gjedde A, Bunney BS, Sass KJ, Elsworth JD, Kier EL, Makuch R, Hoffer PB, et al. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with parkinson’s disease Obstetrical and Gynecological Survey. 48: 413-415.  0.633
1993 Elsworth JD, Roth RH. Deprenyl: Pharmacological aspects of its clinical effects Biogenic Amines. 9: 381-394.  0.6
1992 During MJ, Freese A, Deutch AY, Kibat PG, Sabel BA, Langer R, Roth RH. Biochemical and behavioral recovery in a rodent model of Parkinson's disease following stereotactic implantation of dopamine-containing liposomes. Experimental Neurology. 115: 193-9. PMID 1735466 DOI: 10.1016/0014-4886(92)90053-S  0.759
1992 Innis RB, Malison RT, Al-Tikriti M, Hoffer PB, Sybirska EH, Seibyl JP, Zoghbi SS, Baldwin RM, Laruelle M, Smith EO, Charney DS, Heninger G, Elsworth JD, Roth RH. Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates Synapse. 10: 177-184. PMID 1532675 DOI: 10.1002/Syn.890100302  0.731
1992 Grobin AC, Roth RH, Deutch AY. Regulation of the prefrontal cortical dopamine system by the neuroactive steroid 3a,21-dihydroxy-5a-pregnane-20-one. Brain Research. 578: 351-6. PMID 1511287 DOI: 10.1016/0006-8993(92)90270-J  0.673
1992 Bean AJ, Roth RH. Dopamine-neurotensin interactions in mesocortical neurons. Evidence from microdialysis studies. Annals of the New York Academy of Sciences. 668: 43-53. PMID 1463288 DOI: 10.1111/j.1749-6632.1992.tb27338.x  0.337
1992 Spencer DD, Robbins RJ, Naftolin F, Marek KL, Vollmer T, Leranth C, Roth RH, Price LH, Gjedde A, Bunney BS. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. The New England Journal of Medicine. 327: 1541-8. PMID 1435880 DOI: 10.1097/00006254-199306000-00013  0.388
1992 During MJ, Bean AJ, Roth RH. Effects of CNS stimulants on the in vivo release of the colocalized transmitters, dopamine and neurotensin, from rat prefrontal cortex. Neuroscience Letters. 140: 129-33. PMID 1407692 DOI: 10.1016/0304-3940(92)90698-7  0.666
1992 al-Tikriti MS, Roth RH, Kessler RM, Innis RB. Autoradiographic localization of dopamine D1 and D2 receptors in rat cerebral cortex following unilateral neurotoxic lesions. Brain Research. 575: 39-46. PMID 1387031 DOI: 10.1016/0006-8993(92)90420-E  0.395
1992 Bustos G, Abarca J, Forray MI, Gysling K, Bradberry CW, Roth RH. Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies. Brain Research. 585: 105-15. PMID 1355000 DOI: 10.1016/0006-8993(92)91195-K  0.627
1992 Rosin DL, Clark WA, Goldstein M, Roth RH, Deutch AY. Effects of 6-hydroxydopamine lesions of the prefrontal cortex on tyrosine hydroxylase activity in mesolimbic and nigrostriatal dopamine systems. Neuroscience. 48: 831-9. PMID 1352864 DOI: 10.1016/0306-4522(92)90271-3  0.632
1992 Fetting JH, Stefanek ME, Sheidler VR, Elsworth JD, Piantadosi S, Roth RH. Noradrenergic activity in anticipatory nausea. Psychosomatic Medicine. 54: 641-7. PMID 1333617 DOI: 10.1097/00006842-199211000-00003  0.62
1992 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Collier TJ, Redmond DE. Quantitative behavioral assessment methods for the analysis of graft-induced motor and cognitive function in the MPTP-treated Parkinsonian monkey Journal of Neural Transplantation and Plasticity. 3: 227-228. DOI: 10.1155/Np.1992.227  0.66
1992 Elsworth JD, Sladek JR, Redmond DE, Taylor JR, Collier RJ, Roth RH. Biochemical changes induced by emblyonic substantia nigra transplanted to the striatum of Parkinsonian monkeys Journal of Neural Transplantation and Plasticity. 3: 216-217. DOI: 10.1155/Np.1992.216  0.662
1991 Taylor JR, Lewis VO, Elsworth JD, Pivirotto P, Roth RH, Redmond DE. Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats. Psychopharmacology. 103: 407-14. PMID 2057541 DOI: 10.1007/Bf02244297  0.657
1991 Jatlow P, Elsworth JD, Bradberry CW, Winger G, Taylor JR, Russell R, Roth RH. Cocaethylene: a neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion. Life Sciences. 48: 1787-94. PMID 2020260 DOI: 10.1016/0024-3205(91)90217-Y  0.783
1991 Bradberry CW, Lory JD, Roth RH. The anxiogenic beta-carboline FG 7142 selectively increases dopamine release in rat prefrontal cortex as measured by microdialysis. Journal of Neurochemistry. 56: 748-52. PMID 1993892 DOI: 10.1111/J.1471-4159.1991.Tb01987.X  0.717
1991 Bean AJ, Roth RH. Effects of haloperidol administration on in vivo extracellular dopamine in striatum and prefrontal cortex after partial dopamine lesions. Brain Research. 549: 155-8. PMID 1909923 DOI: 10.1016/0006-8993(91)90613-Z  0.486
1991 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Collier TJ, Redmond DE. Grafting of fetal substantia nigra to striatum reverses behavioral deficits induced by MPTP in primates: a comparison with other types of grafts as controls. Experimental Brain Research. 85: 335-48. PMID 1893983 DOI: 10.1007/Bf00229411  0.695
1991 Bean AJ, Roth RH. Extracellular dopamine and neurotensin in rat prefrontal cortex in vivo: effects of median forebrain bundle stimulation frequency, stimulation pattern, and dopamine autoreceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2694-702. PMID 1880545  0.311
1991 During MJ, Heyes MP, Freese A, Swartz KJ, Matson WR, Markey SP, Martin JB, Roth RH. Indolic and kynurenine pathway metabolites of tryptophan in rat brain: effect of precursor availability on in vivo release. Advances in Experimental Medicine and Biology. 294: 535-9. PMID 1837690 DOI: 10.1007/978-1-4684-5952-4_62  0.485
1991 Lawrence MS, Redmond DE, Elsworth JD, Taylor JR, Roth RH. The D1 receptor antagonist, SCH 23390, induces signs of parkinsonism in African green monkeys. Life Sciences. 49: PL229-34. PMID 1836030 DOI: 10.1016/0024-3205(91)90299-Q  0.688
1991 Ida Y, Elsworth JD, Roth RH. Anxiogenic beta-carboline FG 7142 produces activation of noradrenergic neurons in specific brain regions of rats. Pharmacology, Biochemistry, and Behavior. 39: 791-3. PMID 1784607 DOI: 10.1016/0091-3057(91)90166-Y  0.705
1991 Bradberry CW, Gruen RJ, Berridge CW, Roth RH. Individual differences in behavioral measures: correlations with nucleus accumbens dopamine measured by microdialysis. Pharmacology, Biochemistry, and Behavior. 39: 877-82. PMID 1763106 DOI: 10.1016/0091-3057(91)90047-6  0.703
1991 Bradberry CW, Sprouse JS, Aghajanian GK, Roth RH. Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release. Advances in Experimental Medicine and Biology. 294: 81-9. PMID 1685295 DOI: 10.1007/978-1-4684-5952-4_7  0.648
1991 Elsworth JD, Lawrence MS, Roth RH, Taylor JR, Mailman RB, Nichols DE, Lewis MH, Redmond DE. D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey. The Journal of Pharmacology and Experimental Therapeutics. 259: 595-600. PMID 1682479  0.669
1991 Lovenberg TW, Nichols DE, Nestler EJ, Roth RH, Mailman RB. Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors. Brain Research. 556: 101-7. PMID 1682005 DOI: 10.1016/0006-8993(91)90552-7  0.314
1991 Taylor JR, Lawrence MS, Redmond DE, Elsworth JD, Roth RH, Nichols DE, Mailman RB. Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys. European Journal of Pharmacology. 199: 389-91. PMID 1680717 DOI: 10.1016/0014-2999(91)90508-N  0.697
1991 Bradberry CW, Sprouse JS, Sheldon PW, Aghajanian GK, Roth RH. In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements. Journal of Neuroscience Methods. 36: 85-90. PMID 1676433 DOI: 10.1016/0165-0270(91)90141-L  0.719
1990 Bradberry CW, Sprouse JS, Aghajanian GK, Roth RH. 3,4-methylenedioxymethamphetamine (MDMA)-induced release of endogenous serotonin from the rat dorsal raphe nucleus in vitro: Effects of fluoxetine and tryptophan. Neurochemistry International. 17: 509-13. PMID 20504652 DOI: 10.1016/0197-0186(90)90037-T  0.725
1990 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. MPTP reduces dopamine and norepinephrine concentrations in the supplementary motor area and cingulate cortex of the primate. Neuroscience Letters. 114: 316-22. PMID 2402341 DOI: 10.1016/0304-3940(90)90583-U  0.811
1990 Taylor JR, Elsworth JD, Roth RH, Sladek JR, Redmond DE. Cognitive and motor deficits in the acquisition of an object retrieval/detour task in MPTP-treated monkeys. Brain : a Journal of Neurology. 113: 617-37. PMID 2364263 DOI: 10.1093/Brain/113.3.617  0.681
1990 Tam SY, Elsworth JD, Bradberry CW, Roth RH. Mesocortical dopamine neurons: high basal firing frequency predicts tyrosine dependence of dopamine synthesis. Journal of Neural Transmission. General Section. 81: 97-110. PMID 2363911 DOI: 10.1007/Bf01245830  0.814
1990 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys. Brain Research. 513: 320-4. PMID 2350702 DOI: 10.1016/0006-8993(90)90474-P  0.805
1990 Gruen RJ, Deutch AY, Roth RH. Perinatal diazepam exposure: alterations in exploratory behavior and mesolimbic dopamine turnover. Pharmacology, Biochemistry, and Behavior. 36: 169-75. PMID 2349259 DOI: 10.1016/0091-3057(90)90144-7  0.649
1990 Berger P, Elsworth JD, Reith ME, Tanen D, Roth RH. Complex interaction of cocaine with the dopamine uptake carrier. European Journal of Pharmacology. 176: 251-2. PMID 2311671 DOI: 10.1016/0014-2999(90)90540-M  0.688
1990 Bean AJ, During MJ, Roth RH. Effects of dopamine autoreceptor stimulation on the release of colocalized transmitters: in vivo release of dopamine and neurotensin from rat prefrontal cortex. Neuroscience Letters. 108: 143-8. PMID 2304623 DOI: 10.1016/0304-3940(90)90721-K  0.65
1990 Taylor JR, Elsworth JD, Roth RH, Collier TJ, Sladek JR, Redmond DE. Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys. Progress in Brain Research. 82: 543-59. PMID 2290957 DOI: 10.1016/S0079-6123(08)62645-X  0.725
1990 Moghaddam B, Roth RH, Bunney BS. Characterization of dopamine release in the rat medial prefrontal cortex as assessed by in vivo microdialysis: comparison to the striatum. Neuroscience. 36: 669-76. PMID 2234405 DOI: 10.1016/0306-4522(90)90009-S  0.386
1990 Wolf ME, Roth RH. Autoreceptor regulation of dopamine synthesis. Annals of the New York Academy of Sciences. 604: 323-43. PMID 2171398 DOI: 10.1111/J.1749-6632.1990.Tb32003.X  0.615
1990 Gruen RJ, Elsworth JD, Roth RH. Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam. Brain Research. 514: 151-4. PMID 2162709 DOI: 10.1016/0006-8993(90)90449-L  0.663
1990 Tam SY, Roth RH. Modulation of mesoprefrontal dopamine neurons by central benzodiazepine receptors. I. Pharmacological characterization. The Journal of Pharmacology and Experimental Therapeutics. 252: 989-96. PMID 2157001  0.362
1990 Deutch AY, Elsworth JD, Roth RH, Goldstein M, Deutsch AY. 3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: loss of the dorsolateral striatal dopamine innervation. Brain Research. 527: 96-102. PMID 2126479 DOI: 10.1016/0006-8993(90)91065-O  0.739
1990 Deutch AY, Clark WA, Roth RH. Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress. Brain Research. 521: 311-5. PMID 2119850 DOI: 10.1016/0006-8993(90)91557-W  0.68
1990 Deutch AY, Roth RH. The determinants of stress-induced activation of the prefrontal cortical dopamine system. Progress in Brain Research. 85: 367-402; discussion . PMID 2094906 DOI: 10.1016/S0079-6123(08)62691-6  0.67
1990 Moghaddam B, Gruen RJ, Roth RH, Bunney BS, Adams RN. Effect of L-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies. Brain Research. 518: 55-60. PMID 1975217 DOI: 10.1016/0006-8993(90)90953-9  0.609
1990 Sprouse JS, Bradberry CW, Roth RH, Aghajanian GK. 3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan. European Journal of Pharmacology. 178: 313-20. PMID 1971220 DOI: 10.1016/0014-2999(90)90110-R  0.702
1990 Robbins RJ, Torres-Aleman I, Lebranth C, Bradberry CW, Deutch AY, Welsh S, Roth RH, Spencer D, Redmond DE, Naftolin F. Cryopreservation of human brain tissue. Experimental Neurology. 107: 208-13. PMID 1968397 DOI: 10.1016/0014-4886(90)90137-H  0.729
1990 Berger P, Elsworth JD, Arroyo J, Roth RH. Interaction of [3H]GBR 12935 and GBR 12909 with the dopamine uptake complex in nucleus accumbens. European Journal of Pharmacology. 177: 91-4. PMID 1967129 DOI: 10.1016/0014-2999(90)90554-J  0.736
1990 Jatlow P, Hearn WL, Elsworth JD, Roth RH, Bradberry CW, Taylor JR. Cocaethylene inhibits uptake of dopamine and can reach high plasma concentrations following combined cocaine and ethanol use. Nida Research Monograph. 105: 572-3. PMID 1876124  0.774
1989 Sladek JR, Redmond DE, Collier TJ, Elsworth JD, Roth RH. Transplantation advances in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 4: S120-5. PMID 2786143 DOI: 10.1002/Mds.870040513  0.645
1989 Bradberry CW, Roth RH. Cocaine increases extracellular dopamine in rat nucleus accumbens and ventral tegmental area as shown by in vivo microdialysis. Neuroscience Letters. 103: 97-102. PMID 2779859 DOI: 10.1016/0304-3940(89)90492-8  0.72
1989 Knorr AM, Deutch AY, Roth RH. The anxiogenic beta-carboline FG-7142 increases in vivo and in vitro tyrosine hydroxylation in the prefrontal cortex. Brain Research. 495: 355-61. PMID 2765936 DOI: 10.1016/0006-8993(89)90228-X  0.631
1989 Deutch AY, Gruen RJ, Roth RH. The effects of perinatal diazepam exposure on stress-induced activation of the mesotelencephalic dopamine system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 2: 105-14. PMID 2742725 DOI: 10.1016/0893-133X(89)90013-4  0.64
1989 Bean AJ, Adrian TE, Modlin IM, Roth RH. Dopamine and neurotensin storage in colocalized and noncolocalized neuronal populations. The Journal of Pharmacology and Experimental Therapeutics. 249: 681-7. PMID 2732943  0.389
1989 During MJ, Freese A, Sabel BA, Saltzman WM, Deutch A, Roth RH, Langer R. Controlled release of dopamine from a polymeric brain implant: in vivo characterization. Annals of Neurology. 25: 351-6. PMID 2634975 DOI: 10.1002/Ana.410250406  0.733
1989 Elsworth JD, Deutch AY, Redmond DE, Taylor JR, Sladek JR, Roth RH. Symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates: biochemical changes in striatal regions. Neuroscience. 33: 323-31. PMID 2622529 DOI: 10.1016/0306-4522(89)90212-1  0.782
1989 Bean AJ, During MJ, Deutch AY, Roth RH. Effects of dopamine depletion on striatal neurotensin: biochemical and immunohistochemical studies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 4430-8. PMID 2593006 DOI: 10.1523/Jneurosci.09-12-04430.1989  0.738
1989 Sesack SR, Deutch AY, Roth RH, Bunney BS. Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: an anterograde tract-tracing study with Phaseolus vulgaris leucoagglutinin. The Journal of Comparative Neurology. 290: 213-42. PMID 2592611 DOI: 10.1002/Cne.902900205  0.581
1989 Yurek DM, Deutch AY, Roth RH, Sladek JR. Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Brain Research. 497: 250-9. PMID 2573405 DOI: 10.1016/0006-8993(89)90270-9  0.657
1989 Sprouse JS, Bradberry CW, Roth RH, Aghajanian GK. MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. European Journal of Pharmacology. 167: 375-83. PMID 2572435 DOI: 10.1016/0014-2999(89)90446-9  0.711
1989 Bean AJ, During MJ, Roth RH. Stimulation-induced release of coexistent transmitters in the prefrontal cortex: an in vivo microdialysis study of dopamine and neurotensin release. Journal of Neurochemistry. 53: 655-7. PMID 2568407 DOI: 10.1111/J.1471-4159.1989.Tb07384.X  0.645
1989 Deutch AY, Rosin DL, Goldstein M, Roth RH. 3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: an animal model of olivopontocerebellar atrophy-associated parkinsonism. Experimental Neurology. 105: 1-9. PMID 2568269 DOI: 10.1016/0014-4886(89)90166-0  0.686
1989 Bradberry CW, Karasic DH, Deutch AY, Roth RH. Regionally-specific alterations in mesotelencephalic dopamine synthesis in diabetic rats: association with precursor tyrosine. Journal of Neural Transmission. General Section. 78: 221-9. PMID 2529883 DOI: 10.1007/Bf01249231  0.759
1989 During MJ, Freese A, Heyes MP, Swartz KJ, Markey SP, Roth RH, Martin JB. Neuroactive metabolites of L-tryptophan, serotonin and quinolinic acid, in striatal extracellular fluid. Effect of tryptophan loading. Febs Letters. 247: 438-44. PMID 2523822 DOI: 10.1016/0014-5793(89)81387-0  0.547
1989 During MJ, Heyes MP, Freese A, Markey SP, Martin JB, Roth RH. Quinolinic acid concentrations in striatal extracellular fluid reach potentially neurotoxic levels following systemic L-tryptophan loading. Brain Research. 476: 384-7. PMID 2522807 DOI: 10.1016/0006-8993(89)91265-1  0.479
1988 Sladek JR, Redmond DE, Collier TJ, Blount JP, Elsworth JD, Taylor JR, Roth RH. Fetal dopamine neural grafts: extended reversal of methylphenyltetrahydropyridine-induced parkinsonism in monkeys. Progress in Brain Research. 78: 497-506. PMID 3266802 DOI: 10.1016/S0079-6123(08)60323-4  0.722
1988 Taylor JR, Elsworth JD, Garcia EJ, Grant SJ, Roth RH, Redmond DE. Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal. Psychopharmacology. 96: 121-34. PMID 3147472 DOI: 10.1007/Bf02431544  0.7
1988 Roth RH, Tam SY, Ida Y, Yang JX, Deutch AY. Stress and the mesocorticolimbic dopamine systems. Annals of the New York Academy of Sciences. 537: 138-47. PMID 3059920 DOI: 10.1111/J.1749-6632.1988.Tb42102.X  0.62
1988 Bean AJ, Shepard PD, Bunney BS, Nestler EJ, Roth RH. The effects of pertussis toxin on autoreceptor-mediated inhibition of dopamine synthesis in the rat striatum. Molecular Pharmacology. 34: 715-8. PMID 2974120  0.37
1988 Goldstein M, Lieberman AN, Helmer E, Koslow M, Ransohoff J, Elsworth JD, Roth RH, Deutch AY. Biochemical analysis of caudate nucleus biopsy samples from parkinsonian patients. Annals of Neurology. 24: 685-8. PMID 2904793 DOI: 10.1002/Ana.410240517  0.796
1988 Deutch AY, Bean AJ, Roth RH. Regulation of A8 dopamine neurons by somatostatin. European Journal of Pharmacology. 147: 317-20. PMID 2896598 DOI: 10.1016/0014-2999(88)90796-0  0.601
1988 Deutch AY, Goldstein M, Baldino F, Roth RH. Telencephalic projections of the A8 dopamine cell group. Annals of the New York Academy of Sciences. 537: 27-50. PMID 2462395 DOI: 10.1111/J.1749-6632.1988.Tb42095.X  0.634
1988 BALDING F, DEUTCH AY, ROTH RH, LEWIS ME. In Situ Hybridization Histochemistry of Tyrosine Hydroxylase Messenger RNA in Rat Brain Annals of the New York Academy of Sciences. 537: 484-487. DOI: 10.1111/J.1749-6632.1988.Tb42133.X  0.546
1987 Elsworth JD, Leahy DJ, Roth RH, Redmond DE. Homovanillic acid concentrations in brain, CSF and plasma as indicators of central dopamine function in primates. Journal of Neural Transmission. 68: 51-62. PMID 3806086 DOI: 10.1007/Bf01244639  0.689
1987 Wolf ME, Roth RH. Dopamine neurons projecting to the medial prefrontal cortex possess release-modulating autoreceptors. Neuropharmacology. 26: 1053-9. PMID 3658117 DOI: 10.1016/0028-3908(87)90248-6  0.649
1987 Ida Y, Roth RH. The activation of mesoprefrontal dopamine neurons by FG 7142 is absent in rats treated chronically with diazepam. European Journal of Pharmacology. 137: 185-90. PMID 3609140 DOI: 10.1016/0014-2999(87)90221-4  0.47
1987 Deutch AY, Tam SY, Freeman AS, Bowers MB, Roth RH. Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response. European Journal of Pharmacology. 134: 257-64. PMID 3569414 DOI: 10.1016/0014-2999(87)90356-6  0.703
1987 Deutch AY, Roth RH. Calcitonin gene-related peptide in the ventral tegmental area: selective modulation of prefrontal cortical dopamine metabolism. Neuroscience Letters. 74: 169-74. PMID 3554009 DOI: 10.1016/0304-3940(87)90144-3  0.667
1987 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF. Brain Research. 415: 293-9. PMID 3496938 DOI: 10.1016/0006-8993(87)90211-3  0.8
1987 Sladek JR, Redmond DE, Collier TJ, Haber SN, Elsworth JD, Deutch AY, Roth RH. Transplantation of fetal dopamine neurons in primate brain reverses MPTP induced parkinsonism. Progress in Brain Research. 71: 309-23. PMID 3495818 DOI: 10.1016/S0079-6123(08)61833-6  0.784
1987 Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH. Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum. Life Sciences. 40: 193-202. PMID 3491946 DOI: 10.1016/0024-3205(87)90359-6  0.793
1987 Collier TJ, Redmond DE, Sladek CD, Gallagher MJ, Roth RH, Sladek JR. Intracerebral grafting and culture of cryopreserved primate dopamine neurons. Brain Research. 436: 363-6. PMID 3435833 DOI: 10.1016/0006-8993(87)91680-5  0.371
1987 Deutch AY, Holliday J, Roth RH, Chun LL, Hawrot E. Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 84: 8697-701. PMID 3317419 DOI: 10.1073/Pnas.84.23.8697  0.598
1987 Deutch AY, Bean AJ, Bissette G, Nemeroff CB, Robbins RJ, Roth RH. Stress-induced alterations in neurotensin, somatostatin and corticotropin-releasing factor in mesotelencephalic dopamine system regions. Brain Research. 417: 350-4. PMID 2888514 DOI: 10.1016/0006-8993(87)90462-8  0.682
1987 Sladek JR, Collier TJ, Haber SN, Deutch AY, Elsworth JD, Roth RH, Redmond DE. Reversal of parkinsonism by fetal nerve cell transplants in primate brain. Annals of the New York Academy of Sciences. 495: 641-57. PMID 2886092 DOI: 10.1111/J.1749-6632.1987.Tb23706.X  0.722
1987 Murrin LC, Roth RH. Nigrostriatal dopamine neurons: modulation of impulse-induced activation of tyrosine hydroxylation by dopamine autoreceptors. Neuropharmacology. 26: 591-5. PMID 2885775 DOI: 10.1016/0028-3908(87)90152-3  0.451
1986 Deutch AY, Goldstein M, Roth RH. Activation of the locus coeruleus induced by selective stimulation of the ventral tegmental area. Brain Research. 363: 307-14. PMID 3942901 DOI: 10.1016/0006-8993(86)91016-4  0.651
1986 Elsworth JD, Redmond DE, Roth RH. Effect of morphine treatment and withdrawal on endogenous methionine- and leucine-enkephalin levels in primate brain. Biochemical Pharmacology. 35: 3415-7. PMID 3768031 DOI: 10.1016/0006-2952(86)90447-8  0.658
1986 Deutch AY, Elsworth JD, Goldstein M, Fuxe K, Redmond DE, Sladek JR, Roth RH. Preferential vulnerability of A8 dopamine neurons in the primate to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience Letters. 68: 51-6. PMID 3487756 DOI: 10.1016/0304-3940(86)90228-4  0.793
1986 Galloway MP, Wolf ME, Roth RH. Regulation of dopamine synthesis in the medial prefrontal cortex is mediated by release modulating autoreceptors: studies in vivo. The Journal of Pharmacology and Experimental Therapeutics. 236: 689-98. PMID 3081705  0.749
1986 Sladek JR, Collier TJ, Haber SN, Roth RH, Redmond DE. Survival and growth of fetal catecholamine neurons transplanted into primate brain. Brain Research Bulletin. 17: 809-18. PMID 2879615 DOI: 10.1016/0361-9230(86)90092-4  0.364
1986 Deutch AY, Goldstein M, Roth RH. The ascending projections of the dopaminergic neurons of the substantia nigra, zona reticulata: a combined retrograde tracer-immunohistochemical study. Neuroscience Letters. 71: 257-63. PMID 2879262 DOI: 10.1016/0304-3940(86)90630-0  0.646
1986 Redmond DE, Sladek JR, Roth RH, Collier TJ, Elsworth JD, Deutch AY, Haber S. Transplants of primate neurons. Lancet. 2: 1046. PMID 2877218 DOI: 10.1016/S0140-6736(86)92664-4  0.719
1986 Knorr AM, Wolf ME, Roth RH. K+-dependent stimulation of tyrosine hydroxylation in striatal slices: role of Ca2+/calmodulin and Ca2+/phospholipid-dependent mechanisms. Biochemical Pharmacology. 35: 1929-32. PMID 2872896 DOI: 10.1016/0006-2952(86)90722-7  0.473
1986 Redmond DE, Sladek JR, Roth RH, Collier TJ, Elsworth JD, Deutch AY, Haber S. Fetal neuronal grafts in monkeys given methylphenyltetrahydropyridine. Lancet. 1: 1125-7. PMID 2871381 DOI: 10.1016/S0140-6736(86)91839-8  0.569
1986 Wolf ME, Galloway MP, Roth RH. Regulation of dopamine synthesis in the medial prefrontal cortex: studies in brain slices. The Journal of Pharmacology and Experimental Therapeutics. 236: 699-707. PMID 2869140  0.757
1986 Kafka MS, Benedito MA, Roth RH, Steele LK, Wolfe WW, Catravas GN. Circadian rhythms in catecholamine metabolites and cyclic nucleotide production. Chronobiology International. 3: 101-15. PMID 2824067 DOI: 10.3109/07420528609066354  0.346
1986 Bannon MJ, Deutch AY, Tam SY, Zamir N, Eskay RL, Lee JM, Maggio JE, Roth RH. Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin. Brain Research. 381: 393-6. PMID 2428438 DOI: 10.1016/0006-8993(86)90097-1  0.721
1986 Lee JM, McLean S, Maggio JE, Zamir N, Roth RH, Eskay RL, Bannon MJ. The localization and characterization of substance P and substance K in striatonigral neurons. Brain Research. 371: 152-4. PMID 2423184 DOI: 10.1016/0006-8993(86)90820-6  0.543
1985 Deutch AY, Tam SY, Roth RH. Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra. Brain Research. 333: 143-6. PMID 3995282 DOI: 10.1016/0006-8993(85)90134-9  0.654
1985 Wolf ME, Roth RH. Dopamine autoreceptor stimulation increases protein carboxyl methylation in striatal slices. Journal of Neurochemistry. 44: 291-8. PMID 3964833 DOI: 10.1111/J.1471-4159.1985.Tb07143.X  0.65
1985 Grant SJ, Galloway MP, Mayor R, Fenerty JP, Finkelstein MF, Roth RH, Redmond DE. Precipitated diazepam withdrawal elevates noradrenergic metabolism in primate brain. European Journal of Pharmacology. 107: 127-32. PMID 3920054 DOI: 10.1016/0014-2999(85)90050-0  0.641
1985 Tam SY, Roth RH. Selective increase in dopamine metabolism in the prefrontal cortex by the anxiogenic beta-carboline FG 7142. Biochemical Pharmacology. 34: 1595-8. PMID 3838896 DOI: 10.1016/0006-2952(85)90708-7  0.39
1985 Deutch AY, Maggio JE, Bannon MJ, Kalivas PW, Tam SY, Goldstein M, Roth RH. Substance K and substance P differentially modulate mesolimbic and mesocortical systems. Peptides. 6: 113-22. PMID 2417207 DOI: 10.1016/0196-9781(85)90143-3  0.737
1985 Kalivas PW, Deutch AY, Maggio JE, Mantyh PW, Roth RH. Substance K and substance P in the ventral tegmental area. Neuroscience Letters. 57: 241-6. PMID 2412193 DOI: 10.1016/0304-3940(85)90498-7  0.62
1984 Charney DS, Redmond DE, Galloway MP, Kleber HD, Heninger GR, Murberg M, Roth RH. Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: evidence for noradrenergic hyperactivity. Life Sciences. 35: 1263-72. PMID 6482651 DOI: 10.1016/0024-3205(84)90097-3  0.611
1984 Chiodo LA, Bannon MJ, Grace AA, Roth RH, Bunney BS. Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons. Neuroscience. 12: 1-16. PMID 6462443 DOI: 10.1016/0306-4522(84)90133-7  0.757
1984 Roth RH. CNS dopamine autoreceptors: distribution, pharmacology, and function. Annals of the New York Academy of Sciences. 430: 27-53. PMID 6378032 DOI: 10.1111/J.1749-6632.1984.Tb14497.X  0.411
1983 Elsworth JD, Roth RH, Redmond DE. Relative importance of 3-methoxy-4-hydroxyphenylglycol and 3,4-dihydroxyphenylglycol as norepinephrine metabolites in rat, monkey, and humans. Journal of Neurochemistry. 41: 786-93. PMID 6875564 DOI: 10.1111/J.1471-4159.1983.Tb04809.X  0.648
1983 Ko GN, Elsworth JD, Roth RH, Rifkin BG, Leigh H, Redmond DE. Panic-induced elevation of plasma MHPG levels in phobic-anxious patients. Effects of clonidine and imipramine. Archives of General Psychiatry. 40: 425-30. PMID 6838322 DOI: 10.1001/Archpsyc.1983.01790040079011  0.644
1983 Bannon MJ, Wolf ME, Roth RH. Pharmacology of dopamine neurons innervating the prefrontal, cingulate and piriform cortices. European Journal of Pharmacology. 92: 119-25. PMID 6628534 DOI: 10.1016/0014-2999(83)90116-4  0.752
1983 Galloway MP, Roth RH. Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo. The Journal of Pharmacology and Experimental Therapeutics. 227: 1-8. PMID 6194283  0.62
1983 Reinhard JF, Galloway MP, Roth RH. Noradrenergic modulation of serotonin synthesis and metabolism. II. Stimulation by 3-isobutyl-1-methylxanthine. The Journal of Pharmacology and Experimental Therapeutics. 226: 764-9. PMID 6193267  0.628
1983 Galloway MP, Roth RH. Clonidine prevents methylxanthine stimulation of norepinephrine metabolism in rat brain. Journal of Neurochemistry. 40: 246-51. PMID 6184449 DOI: 10.1111/J.1471-4159.1983.Tb12678.X  0.66
1983 Bannon MJ, Roth RH. Pharmacology of mesocortical dopamine neurons. Pharmacological Reviews. 35: 53-68. PMID 6138783  0.637
1982 Elsworth JD, Redmond DE, Roth RH. Plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) as indices of brain norepinephrine metabolism in primates. Brain Research. 235: 115-24. PMID 7188317 DOI: 10.1016/0006-8993(82)90200-1  0.628
1982 Kendler KS, Heninger GR, Roth RH. Influence of dopamine agonists on plasma and brain levels of homovanillic acid. Life Sciences. 30: 2063-9. PMID 7109836 DOI: 10.1016/0024-3205(82)90447-7  0.417
1982 Reinhard JF, Bannon MJ, Roth RH. Acceleration by stress of dopamine synthesis and metabolism in prefrontal cortex: antagonism by diazepam. Naunyn-Schmiedeberg's Archives of Pharmacology. 318: 374-7. PMID 7078670 DOI: 10.1007/BF00501182  0.649
1982 Bannon MJ, Reinhard JF, Bunney EB, Roth RH. Unique response to antipsychotic drugs is due to absence of terminal autoreceptors in mesocortical dopamine neurones. Nature. 296: 444-6. PMID 7063040 DOI: 10.1038/296444a0  0.651
1982 Holcomb HH, Bannon MJ, Roth RH. Striatal dopamine autoreceptors uninfluenced by chronic administration of antidepressants. European Journal of Pharmacology. 82: 173-8. PMID 6813129 DOI: 10.1016/0014-2999(82)90507-6  0.65
1982 Roth RH, Elsworth JD, Redmond DE. Clonidine suppression of noradrenergic hyperactivity during morphine withdrawal by clonidine: biochemical studies in rodents and primates. The Journal of Clinical Psychiatry. 43: 42-6. PMID 6806253  0.67
1982 Swann AC, Elsworth JD, Charney DS, Jablons DM, Roth RH, Redmond DE, Maas JW. Brain catecholamine metabolites and behavior in morphine withdrawal. European Journal of Pharmacology. 86: 167-75. PMID 6297931 DOI: 10.1016/0014-2999(82)90314-4  0.681
1982 Billingsley ML, Roth RH. Dopamine agonists stimulate protein carboxylmethylation in striatal synaptosomes. The Journal of Pharmacology and Experimental Therapeutics. 223: 681-8. PMID 6183421  0.321
1982 Bacopoulos NG, Bustos G, Redmond DE, Roth RH. Chronic treatment with haloperidol or fluphenazine decanoate: regional effects on dopamine and serotonin metabolism in primate brain. The Journal of Pharmacology and Experimental Therapeutics. 221: 22-8. PMID 6174729  0.307
1981 Bacopoulos NG, Roth RH. Apomorphine-haloperidol interactions: different types of antagonism in cortical and subcortical brain regions. Brain Research. 205: 313-9. PMID 7470869  0.388
1981 Riker DK, Zito RA, Roth RH. Lidocaine selectively diminishes medullary serotonin metabolism in the rat. Neuropharmacology. 20: 1233-6. PMID 7322300 DOI: 10.1016/0028-3908(81)90071-X  0.375
1981 Michaud RL, Bannon MJ, Roth RH. The use of c8-octyl columns for the analysis of catecholamines by ion-pair reversed-phase liquid chromatography with amperometric detection. Journal of Chromatography. 225: 335-45. PMID 7298769 DOI: 10.1016/S0378-4347(00)80282-0  0.561
1981 Bannon MJ, Bunney EB, Roth RH. Mesocortical dopamine neurons: rapid transmitter turnover compared to other brain catecholamine systems. Brain Research. 218: 376-82. PMID 7272743  0.659
1981 Kendler KS, Heninger GR, Roth RH. Brain contribution to the haloperidol-induced increase in plasma homovanillic acid. European Journal of Pharmacology. 71: 321-6. PMID 7250191 DOI: 10.1016/0014-2999(81)90034-0  0.358
1981 Bannon MJ, Michaud RL, Roth RH. Mesocortical dopamine neurons. Lack of autoreceptors modulating dopamine synthesis. Molecular Pharmacology. 19: 270-5. PMID 6785571  0.641
1981 Braszko JJ, Bannon MJ, Bunney BS, Roth RH. Intrastriatal kainic acid: acute effects on electrophysiological and biochemical measures of nigrostriatal dopaminergic activity. The Journal of Pharmacology and Experimental Therapeutics. 216: 289-93. PMID 6257886  0.623
1981 Riker DK, Messer A, Roth RH. Increased noradrenergic metabolism in the cerebellum of the mouse mutant dystonia musculorum. Journal of Neurochemistry. 37: 649-54. PMID 6115889 DOI: 10.1111/J.1471-4159.1982.Tb12536.X  0.35
1981 Zigun JR, Bannon MJ, Roth RH. Comparison of two alpha-noradrenergic agonists (clonidine and guanfacine) on norepinephrine turnover in the cortex of rats during morphine abstinence. European Journal of Pharmacology. 70: 565-70. PMID 6113150 DOI: 10.1016/0014-2999(81)90368-X  0.586
1980 Umezu K, Bustos G, Roth RH. Regional inhibitory effect of ethanol on monoamine synthesis regulation within the brain. Biochemical Pharmacology. 29: 2477-83. PMID 7426055 DOI: 10.1016/0006-2952(80)90352-4  0.343
1980 Roth RH, Doherty JD, Walters JR. Gamma-hydroxybutyrate: a role in the regulation of central dopaminergic neurons? Brain Research. 189: 556-60. PMID 7370791 DOI: 10.1016/0006-8993(80)90368-6  0.523
1980 Wheeler SC, Roth RH. Tolerance to fluphenazine and supersensitivity to apomorphine in central dopaminergic systems after chronic fluphenazine decanoate treatment. Naunyn-Schmiedeberg's Archives of Pharmacology. 312: 151-9. PMID 7190650 DOI: 10.1007/BF00569724  0.461
1980 Crawley JN, Maas JW, Roth RH. Biochemical evidence for simultaneous activation of multiple locus coeruleus efferents. Life Sciences. 26: 1373-8. PMID 6991843 DOI: 10.1016/0024-3205(80)90039-9  0.325
1980 Bannon MJ, Bunney EB, Zigun JR, Skirboll LR, Roth RH. Presynaptic dopamine receptors: insensitivity to kainic acid and the development of supersensitivity following chronic haloperidol. Naunyn-Schmiedeberg's Archives of Pharmacology. 312: 161-5. PMID 6772975 DOI: 10.1007/BF00569725  0.663
1980 Marek KL, Roth RH. Ergot alkaloids: interaction with presynaptic dopamine receptors in the neostriatum and olfactory tubercles. European Journal of Pharmacology. 62: 137-46. PMID 6769681 DOI: 10.1016/0014-2999(80)90270-8  0.454
1980 Bustos G, Simon J, Roth RH. Tyrosine hydroxylase regulation: apparent kinetic alterations following incubation of brain slices in a sodium-free medium. Journal of Neurochemistry. 35: 47-57. PMID 6108991 DOI: 10.1111/J.1471-4159.1980.Tb12488.X  0.372
1980 Bannon MJ, Grace AA, Bunney BS, Roth RH. Evidence for an irreversible interaction of bromocryptine with central dopamine receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 312: 37-41. PMID 6104795 DOI: 10.1007/BF00502572  0.728
1980 Riker DK, Gold BI, Roth RH. Avian nocturnal hyperactivity: Neurotransmitter metabolism in the basal ganglia Brain Research Bulletin. 5: 369-374. DOI: 10.1016/0361-9230(80)90059-3  0.446
1979 Crawley JN, Laverty R, Roth RH. Clonidine reversal of increased norepinephrine metabolite levels during morphine withdrawal. European Journal of Pharmacology. 57: 247-50. PMID 573692 DOI: 10.1016/0014-2999(79)90372-8  0.321
1979 Wang RY, de Montigny C, Gold BI, Roth RH, Aghajanian GK. Denervation supersensitivity to serotonin in rat forebrain: single cell studies. Brain Research. 178: 479-97. PMID 509215 DOI: 10.1016/0006-8993(79)90708-X  0.428
1979 Bacopoulos NG, Hattox SE, Roth RH. 3,4-Dihydroxyphenylacetic acid and homovanillic acid in rat plasma: possible indicators of central dopaminergic activity. European Journal of Pharmacology. 56: 225-36. PMID 477719 DOI: 10.1016/0014-2999(79)90175-4  0.385
1979 Rogawski MA, Roth RH, Aghajanian GK. Melatonin: deacetylation to 5-methoxytryptamine by liver but not brain aryl acylamidase. Journal of Neurochemistry. 32: 1219-26. PMID 285213 DOI: 10.1111/j.1471-4159.1979.tb11049.x  0.481
1979 Ando N, Gold BI, Bird ED, Roth RH. REGIONAL BRAIN LEVELS OF γ‐HYDROXYBUTYRATE IN HUNTINGTON'S DISEASE Journal of Neurochemistry. 32: 617-622. PMID 153950 DOI: 10.1111/J.1471-4159.1979.Tb00392.X  0.301
1979 Bacopoulos NG, Heninger GR, Roth RH. Effects of haloperidol and probenecid on plasma and CSF dopamine metabolites in the rhesus monkey (Macacca mulatta). Life Sciences. 23: 1805-12. PMID 102888 DOI: 10.1016/0024-3205(78)90112-1  0.359
1979 Nowycky MC, Roth RH. Chronic gamma-butyrolactone (GBL) treatment: a potential model of dopamine hypoactivity. Naunyn-Schmiedeberg's Archives of Pharmacology. 309: 247-54. PMID 43476 DOI: 10.1007/BF00504757  0.445
1979 Bustos G, Roth RH. Does cyclic AMP-dependent phosphorylation account for the activation of tyrosine hydroxylase produced by depolarization of central dopaminergic neurons? Biochemical Pharmacology. 28: 3026-8. PMID 42409 DOI: 10.1016/0006-2952(79)90605-1  0.33
1979 Bacopoulos NC, Spokes EG, Bird ED, Roth RH. Antipsychotic drug action in schizophrenic patients: effect on cortical dopamine metabolism after long-term treatment. Science (New York, N.Y.). 205: 1405-7. PMID 38504 DOI: 10.1126/SCIENCE.38504  0.412
1979 Bustos G, Roth RH. Tyrosine hydroxylase regulation in rat striatal and olfactory tubercle slices--I. Activation induced by exposure to a calcium-free and high-magnesium medium. Biochemical Pharmacology. 28: 1923-31. PMID 36899 DOI: 10.1016/0006-2952(79)90646-4  0.329
1979 Riker DK, Gold BI, Roth RH. Regional distribution of GABA, glutamic acid decarboxylase, dopamine metabolites, and high-affinity choline accumulation in the brain of the white-throated sparrow: relationship to avian nocturnal hyperactivity Brain Research Bulletin. 4: 706. DOI: 10.1016/0361-9230(79)90243-0  0.371
1978 Gold BI, Simon JR, Roth RH. Glutamic acid decarboxylase activity in striatal slices: Persistent increase following depolarization Life Sciences. 22: 187-193. PMID 628309 DOI: 10.1016/0024-3205(78)90536-2  0.336
1978 Choi RL, Roth RH. Development of supersensitivity of apomorphine-induced increases in acetylcholine levels and stereotype after chronic fluphenazine treatment. Neuropharmacology. 17: 59-64. PMID 565881 DOI: 10.1016/0028-3908(78)90174-0  0.414
1978 Nowycky MC, Walters JR, Roth RH. Dopaminergic neurons: effect of acute and chronic morphine administration on single cell activity and transmitter metabolism. Journal of Neural Transmission. 42: 99-116. PMID 206664 DOI: 10.1007/Bf01675349  0.598
1978 Simon JR, Hegstrand LR, Roth RH. Regulation of tyrosine hydroxylase from human pheochromocytoma bovine adrenal and rat striatum Life Sciences. 22: 421-428. PMID 25366 DOI: 10.1016/0024-3205(78)90289-8  0.385
1978 Bustos G, Roth RH, Morgenroth VH, Hancke JL. Tyrosine hydroxylase activation and transmitter release from central noradrenergic neurons by electrical field stimulation. Naunyn-Schmiedeberg's Archives of Pharmacology. 301: 149-56. PMID 24807 DOI: 10.1007/BF00507030  0.308
1978 Nowycky MC, Roth RH. Dopaminergic neurons: Role of presynaptic receptors in the regulation of transmitter biosynthesis Progress in Neuro-Psychopharmacology. 2: 139-158. DOI: 10.1016/0364-7722(78)90061-9  0.435
1977 Roth RH, Nowycky MC. Dopaminergic neurons: effects elicited by gamma-hydroxybutyrate are reversed by picrotoxin. Biochemical Pharmacology. 26: 2079-82. PMID 921818 DOI: 10.1016/0006-2952(77)90022-3  0.356
1977 Elchisak MA, Maas JW, Roth RH. Dihydroxyphenylacetic acid conjugate: natural occurrence and demonstration of probenecid-induced accumulation in rat striatum, olfactory tubercles and frontal cortex. European Journal of Pharmacology. 41: 369-78. PMID 844481 DOI: 10.1016/0014-2999(77)90257-6  0.422
1977 Nowycky MC, Roth RH. Presynaptic dopamine receptors. Development of supersensitivity following treatment with fluphenazine decanoate. Naunyn-Schmiedeberg's Archives of Pharmacology. 300: 247-54. PMID 600312 DOI: 10.1007/BF00500967  0.456
1977 Roth RH, Nowycky MC, Walters JR, Morgenroth VH. gamma-Hydroxybutyrate: effects on nonstriatal dopaminergic neurons. Advances in Biochemical Psychopharmacology. 16: 483-8. PMID 18897  0.476
1976 Boadle-Biber MC, Roth RH. Formation of dopamine and noradrenaline in rat vas deferens: comparison with guinea-pig vas deferens. British Journal of Pharmacology. 55: 73-8. PMID 1182351 DOI: 10.1111/j.1476-5381.1975.tb07613.x  0.383
1976 Herr BE, Gallager DW, Roth RH. Tryptophan hydroxylase: activation in vivo following stimulation of central serotonergic neurons. Biochemical Pharmacology. 24: 2019-23. PMID 1082337 DOI: 10.1016/0006-2952(75)90397-4  0.32
1976 Sethy VH, Roth RH, Walters JR, Marini J, Van Woert MH. Effect of anesthetic doses of gamma-hydroxybutyrate on the acetylcholine content of rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 295: 9-14. PMID 1004645 DOI: 10.1007/Bf00509765  0.539
1976 Roth RH. Striatal dopamine and gamma-hydroxybutyrate. Pharmacology & Therapeutics. Part B: General & Systematic Pharmacology. 2: 71-88. PMID 817333 DOI: 10.1016/0306-039X(76)90020-9  0.454
1976 Krueger BK, Forn J, Walters JR, Roth RH, Greengard P. Stimulation by dopamine of adenosine cyclic 3',5'-monophosphate formation in rat caudate nucleus: effect of lesions of the nigro-neostriatal pathway. Molecular Pharmacology. 12: 639-48. PMID 183096  0.527
1976 Roth RH, Murrin LC, Walters JR. Central dopaminergic neurons: effects of alterations in impulse flow on the accumulation of dihydroxyphenylacetic acid. European Journal of Pharmacology. 36: 163-71. PMID 177297 DOI: 10.1016/0014-2999(76)90268-5  0.642
1976 Walters JR, Roth RH. Dopaminergic neurons: an in vivo system for measuring drug interactions with presynaptic receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 296: 5-14. PMID 13315 DOI: 10.1007/Bf00498834  0.647
1976 Murrin LC, Roth RH. Dopaminergic neurons: reversal of effects elicited by γ butyrolactone by stimulation of the nigro neostriatal pathway Naunyn-Schmied.Arch.Pharm.. 295: 15-20. PMID 12482 DOI: 10.1007/Bf00509766  0.474
1976 Bustos G, Roth RH, Morgenroth VH. Activation of tyrosine hydroxylase in rat striatal slices by K+-depolarization--effect of ethanol. Biochemical Pharmacology. 25: 2493-7. PMID 10925 DOI: 10.1016/0006-2952(76)90455-X  0.316
1976 Bustos G, Roth RH. Effect of acute ethanol treatment on transmitter synthesis and metabolism in central dopaminergic neurons. The Journal of Pharmacy and Pharmacology. 28: 580-2. PMID 8613 DOI: 10.1111/j.2042-7158.1976.tb02799.x  0.312
1976 Morgenroth VH, Walters JR, Roth RH. Dopaminergic neurons--alteration in the kinetic properties of tyrosine hydroxylase after cessation of impulse flow. Biochemical Pharmacology. 25: 655-61. PMID 6035 DOI: 10.1016/0006-2952(76)90240-9  0.6
1976 Walters JR, Roth RH. Dopaminergic neurons - alteration in the sensitivity of tyrosine hydroxylase to inhibition by endovenous dopamine after cessation of impulse flow. Biochemical Pharmacology. 25: 649-54. PMID 6034 DOI: 10.1016/0006-2952(76)90239-2  0.64
1976 Murrin LC, Roth RH. Dopaminergic neurons: Reversal of effects elicited by γ-butyrolactone by stimulation of the nigro-neostriatal pathway Naunyn-Schmiedeberg's Archives of Pharmacology. 295: 15-20. DOI: 10.1007/BF00509766  0.368
1975 Bunney BS, Walters JR, Kuhar MJ, Roth RH, Aghajanian GK. D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons. Psychopharmacology Communications. 1: 177-90. PMID 1223998  0.716
1975 Nybäck HV, Walters JR, Aghajanian GK, Roth RH. Tricyclic antidepressants: effects on the firing rate of brain noradrenergic neurons. European Journal of Pharmacology. 32: 302-12. PMID 1149813 DOI: 10.1016/0014-2999(75)90297-6  0.669
1975 Roth RH, Morgenroth VH, Salzman PM. Tyrosine hydroxylase: allosteric activation induced by stimulation of central noradrenergic neurons Naunyn-Schmied.Arch.Pharm.. 289: 327-343. PMID 240133 DOI: 10.1007/BF00508408  0.307
1975 Harris JE, Baldessarini RJ, Roth RH. Amphetamine-induced inhibition of tyrosine hydroxylation in homogenates of rat corpus striatum. Neuropharmacology. 14: 457-471. PMID 239367 DOI: 10.1016/0028-3908(75)90049-0  0.463
1975 Harris JE, Baldessarini RJ, Morgenroth VH, Roth RH. Activation by cyclic 3':5'-adenosine monophosphate of tyrosine hydroxylase in the rat brain. Proceedings of the National Academy of Sciences of the United States of America. 72: 789-93. PMID 236558 DOI: 10.1073/PNAS.72.3.789  0.4
1975 Walters JR, Bunney BS, Roth RH. Piribedil and apomorphine: pre- and postsynaptic effects on dopamine synthesis and neuronal activity. Advances in Neurology. 9: 273-84. PMID 167566  0.545
1975 Nowycky MC, Sgaragli GP, Cooper JR, Roth RH. Effect of collagenase on the release of dopamine and acetylcholine from slices of rat corpus striatum. Journal of Neurochemistry. 24: 1279-81. PMID 165267 DOI: 10.1111/j.1471-4159.1975.tb03914.x  0.452
1975 Roth RH, Walters JR, Murrin LC, Morgenroth VH. Dopamine neurons: role of impulse flow and presynaptic receptors in the regulation of tyrosine hydroxylase. Psychopharmacology Bulletin. 11: 8. PMID 723  0.527
1974 Kuhar MJ, Aghajanian GK, Roth RH. Serotonin neurons: a synaptic mechanism for the reuptake of serotonin. Advances in Biochemical Psychopharmacology. 10: 287-95. PMID 4846544  0.573
1974 Wilson WS, Roth RH, Cooper JR. The subcellular localization of noradrenaline and dopamine in bovine superior cervical ganglion. Life Sciences. 13: 281-5. PMID 4752484 DOI: 10.1016/0024-3205(73)90219-1  0.425
1974 Walters JR, Roth RH. Dopaminergic neurons: drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow. The Journal of Pharmacology and Experimental Therapeutics. 191: 82-91. PMID 4153880  0.472
1974 Harris JE, Morgenroth VH, Roth RH, Baldessarini RJ. Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP. Nature. 252: 156-158. PMID 4153840 DOI: 10.1038/252156A0  0.315
1974 Roth RH, Walters JR, Morgenroth VH. Proceedings: Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons. Psychopharmacology Bulletin. 10: 40. PMID 4153706  0.462
1974 Roth RH, Salzman PM, Morgenroth VH. Noradrenergic neurons: Allosteric activation of hippocampal tyrosine hydroxylase by stimulation of the locus coeruleus Biochemical Pharmacology. 23: 2779-2784. PMID 4153688 DOI: 10.1016/0006-2952(74)90051-3  0.309
1974 Roth RH, Walters JR, Morgenroth VH. Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons. Advances in Biochemical Psychopharmacology. 12: 369-84. PMID 4153663  0.461
1973 Roth RH. Effect of anesthetic doses of hydroxybutyrate on subcortical concentrations of homovanillic acid. European Journal of Pharmacology. 15: 52-9. PMID 5161341 DOI: 10.1016/0014-2999(71)90078-1  0.454
1973 Korf J, Aghajanian GK, Roth RH. Increased turnover of norepinephrine in the rat cerebral cortex during stress: role of the locus coeruleus. Neuropharmacology. 12: 933-8. PMID 4750561 DOI: 10.1016/0028-3908(73)90024-5  0.565
1973 Sethy VH, Roth RH, Kuhar MJ, Van Woert MH. Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus. Neuropharmacology. 12: 819-23. PMID 4746445 DOI: 10.1016/0028-3908(73)90034-8  0.507
1973 Walters JR, Roth RH, Aghajanian GK. Dopaminergic neurons: similar biochemical and histochemical effects of gamma-hydroxybutyrate and acute lesions of the nigro-neostriatal pathway. The Journal of Pharmacology and Experimental Therapeutics. 186: 630-9. PMID 4728341  0.611
1973 Korf J, Aghajanian GK, Roth RH. Stimulation and destruction of the locus coeruleus: opposite effects on 3-methoxy-4-hydroxyphenylglycol sulfate levels in the rat cerebral cortex. European Journal of Pharmacology. 21: 305-10. PMID 4708068 DOI: 10.1016/0014-2999(73)90131-3  0.568
1973 Touloukian RJ, Aghajanian G, Roth RH. Adrenergic hyperactivity of the aganglionic colon Journal of Pediatric Surgery. 8: 191-195. PMID 4698355 DOI: 10.1016/S0022-3468(73)80084-3  0.488
1973 Kuhar MJ, Sethy VH, Roth RH, Aghajanian GK. Choline: selective accumulation by central cholinergic neurons. Journal of Neurochemistry. 20: 581-93. PMID 4698301 DOI: 10.1111/J.1471-4159.1973.Tb12157.X  0.645
1973 Korf J, Roth RH, Aghajanian GK. Alterations in turnover and endogenous levels of norepinephrine in cerebral cortex following electrical stimulation and acute axotomy of cerebral noradrenergic pathways. European Journal of Pharmacology. 23: 276-82. PMID 4583563 DOI: 10.1016/0014-2999(73)90095-2  0.532
1973 Bunney BS, Walters JR, Roth RH, Aghajanian GK. Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity. The Journal of Pharmacology and Experimental Therapeutics. 185: 560-71. PMID 4576427  0.629
1973 Bunney BS, Aghajanian GK, Roth RH. Comparison of effects of L-dopa, amphetamine and apomorphine on firing rate of rat dopaminergic neurones. Nature: New Biology. 245: 123-5. PMID 4518113 DOI: 10.1038/Newbio245123A0  0.645
1973 Sethy VH, Kuhar MJ, Roth RH, Van Woert MH, Aghajanian GK. Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus. Brain Research. 55: 481-4. PMID 4351629 DOI: 10.1016/0006-8993(73)90318-1  0.627
1973 Aghajanian GK, Kuhar MJ, Roth RH. Serotonin-containing neuronal perikarya and terminals: differential effects of P-chlorophenylalanine. Brain Research. 54: 85-101. PMID 4267802 DOI: 10.1016/0006-8993(73)90036-X  0.58
1973 Roth RH. Inhibition by γ-hydroxybutyrate of chlorpromazine-induced increase in homovanillic acid British Journal of Pharmacology. 47: 408-414. PMID 4146575 DOI: 10.1111/J.1476-5381.1973.Tb08338.X  0.307
1973 Roth RH, Walters JR, Aghajanian GK. Effect of impulse flow on the release and synthesis of dopamine in the striatum Life Sciences. 13: cxxxix-cxl. DOI: 10.1016/0024-3205(73)90387-1  0.716
1972 Bustos G, Roth RH. Release of monoamines from the striatum and hypothalamus: effect of -hydroxybutyrate. British Journal of Pharmacology. 46: 101-15. PMID 5084815 DOI: 10.1111/j.1476-5381.1972.tb06853.x  0.395
1972 Touloukian RJ, Aghajanian GK, Roth RH. Adrenergic denervation of the hypertrophied gut remnant. Annals of Surgery. 176: 633-7. PMID 5079824 DOI: 10.1097/00000658-197211000-00009  0.489
1972 Kuhar MJ, Aghajanian GK, Roth RH. Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence. Brain Research. 44: 165-76. PMID 5056975 DOI: 10.1016/0006-8993(72)90372-1  0.62
1972 Bustos G, Roth RH. Effect of -hydroxybutyrate on the release of monoamines from the rat striatum. British Journal of Pharmacology. 44: 817-20. PMID 5041458 DOI: 10.1111/j.1476-5381.1972.tb07322.x  0.402
1972 Bustos G, Kuhar MJ, Roth RH. Effect of gamma-hydroxybutyrate and gamma-butyrolactone on dopamine synthesis and uptake by rat striatum. Biochemical Pharmacology. 21: 2649-52. PMID 4661622 DOI: 10.1016/0006-2952(72)90233-X  0.577
1972 Kuhar MJ, Roth RH, Aghajanian GK. Synthesis of catecholamines in the locus coeruleus from 3 H-tyrosine in vivo. Biochemical Pharmacology. 21: 2280-2. PMID 4646193 DOI: 10.1016/0006-2952(72)90047-0  0.586
1972 Walters JR, Roth RH. Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum. Biochemical Pharmacology. 21: 2111-21. PMID 4645883 DOI: 10.1016/0006-2952(72)90164-5  0.654
1972 Kuhar MJ, Roth RH, Aghajanian GK. Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake. The Journal of Pharmacology and Experimental Therapeutics. 181: 36-45. PMID 4552069  0.578
1972 BOWERS MB, ROTH RH. Interaction of atropine‐like drugs with dopamine‐containing neurones in rat brain British Journal of Pharmacology. 44: 301-306. PMID 4148918 DOI: 10.1111/j.1476-5381.1972.tb07267.x  0.44
1972 Boadle-Biber MC, Roth RH. Factors modifying the synthesis of dopamine from tyrosine in pedal ganglia of Mercenaria mercenaria (mollusca) Comparative and General Pharmacology. 3: 61-74. DOI: 10.1016/0010-4035(72)90042-0  0.345
1971 Roth RH, Suhr Y. Mechanism of the gamma-hydroxybutyrate-induced increase in brain dopamine and its relationship to "sleep". Biochemical Pharmacology. 19: 3001-12. PMID 5513037 DOI: 10.1016/0006-2952(70)90086-9  0.492
1971 Hughes J, Roth RH. Evidence that angiotensin enhances transmitter release during sympathetic nerve stimulation. British Journal of Pharmacology. 41: 239-55. PMID 4324592 DOI: 10.1111/j.1476-5381.1971.tb08025.x  0.303
1971 Kuhar MJ, Roth RH, Aghajanian GK. Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions. Brain Research. 35: 167-76. PMID 4257335 DOI: 10.1016/0006-8993(71)90602-0  0.624
1970 Roth RH. Formation and regional distribution of γ-hydroxybutyric acid in mammalian brain Biochemical Pharmacology. 19: 3013-3019. PMID 5513038 DOI: 10.1016/0006-2952(70)90087-0  0.31
1970 Stjärne L, Roth RH, Bloom FE, Giarman NJ. Norepinephrine concentrating mechanisms in sympathetic nerve trunks. The Journal of Pharmacology and Experimental Therapeutics. 171: 70-9. PMID 5410939  0.541
1970 Roth RH, Giarman NJ. Natural occurrence of gamma-hydroxybutyrate in mammalian brain Biochemical Pharmacology. 19: 1087-1093. DOI: 10.1016/0006-2952(70)90370-9  0.606
1969 Roth RH, Giarman NJ. Conversion in vivo of gamma-aminobutyric to gamma-hydroxybutyric acid in the rat. Biochemical Pharmacology. 18: 247-50. PMID 5780990 DOI: 10.1016/0006-2952(69)90032-X  0.599
1969 DeFeudis FV, Delgado JM, Roth RH. Content and release of amino-acids and catecholamines in monkey brain. Nature. 223: 74-5. PMID 4978298 DOI: 10.1038/223074A0  0.32
1968 Roth RH, Stjärne L, Levine RJ, Giarman NJ. Abnormal regulation of catecholamine synthesis in pheochromocytoma. The Journal of Laboratory and Clinical Medicine. 72: 397-403. PMID 5674070 DOI: 10.5555/Uri:Pii:0022214368901613  0.612
1968 Roth RH, Stone EA. The action of reserpine on noradrenaline biosynthesis in sympathetic nerve tissue Biochemical Pharmacology. 17: 1581-1590. PMID 5672819 DOI: 10.1016/0006-2952(68)90218-9  0.379
1968 Roth RH, Stjärne L, Bloom FE, Giarman NJ. Light and heavy norepinephrine storage particles in the rat heart and in bovine splenic nerve. The Journal of Pharmacology and Experimental Therapeutics. 162: 203-12. PMID 5666978  0.549
1968 Stjärne L, Roth RH, Giarman NJ. Effects of desipramine on noradrenaline uptake into isolated nerve granules. Biochemical Pharmacology. 17: 1464-6. PMID 5659790 DOI: 10.1016/0006-2952(68)90084-1  0.593
1968 Roth RH, Giarman NJ. Evidence that central nervous system depression by 1,4-butanediol in mediated through a metabolite, gamma-hydroxybutyrate. Biochemical Pharmacology. 17: 735-9. PMID 5649891 DOI: 10.1016/0006-2952(68)90010-5  0.627
1967 Roth RH, Stjärne L, von Euler US. Factors influencing the rate of norepinephrine biosynthesis in nerve tissue. The Journal of Pharmacology and Experimental Therapeutics. 158: 373-7. PMID 4965285  0.444
1967 Roth RH, Levy R, Giarman NJ. Dependence of rat serum lactonase upon calcium. Biochemical Pharmacology. 16: 596-8. PMID 4962217 DOI: 10.1016/0006-2952(67)90110-4  0.587
1966 Roth RH, Stjärne L, von Euler US. Acceleration of noradrenaline biosynthesis by nerve stimulation. Life Sciences. 5: 1071-5. PMID 4960408  0.446
1966 Roth RH, Delgado JM, Giarman NJ. Gamma-butyrolactone and gamma-hydroxybutyric acid. II. The pharmacologically active form. International Journal of Neuropharmacology. 5: 421-8. PMID 4293055 DOI: 10.1016/0028-3908(66)90007-4  0.629
1966 Roth RH, Giarman NJ. γ-Butyrolactone and γ-hydroxybutyric acid—I: Distribution and metabolism☆ Biochemical Pharmacology. 15: 1333-1348. DOI: 10.1016/0006-2952(66)90045-1  0.618
1965 ROTH RH, GIARMAN NJ. PRELIMINARY REPORT ON THE METABOLISM OF GAMMA-BUTYROLACTONE AND GAMMA-HYDROXYBUTYRIC ACID. Biochemical Pharmacology. 14: 177-8. PMID 14332463 DOI: 10.1016/0006-2952(65)90073-0  0.579
1964 GIARMAN NJ, ROTH RH. DIFFERENTIAL ESTIMATION OF GAMMA-BUTYROLACTONE AND GAMMA-HYDROXYBUTYRIC ACID IN RAT BLOOD AND BRAIN. Science (New York, N.Y.). 145: 583-4. PMID 14163782 DOI: 10.1126/Science.145.3632.583  0.616
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