Susann Brady-Kalnay - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Neuroscience Biology, Cell Biology, Molecular Biology

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Molyneaux K, Laggner C, Vincent J, Brady-Kalnay S. Small molecule antagonists of PTPmu identified by artificial intelligence-based computational screening block glioma cell migration and growth. Plos One. 18: e0288980. PMID 37494327 DOI: 10.1371/journal.pone.0288980  0.379
2023 Molyneaux K, Laggner C, Brady-Kalnay SM. Artificial Intelligence-Based Computational Screening and Functional Assays Identify Candidate Small Molecule Antagonists of PTPmu-Dependent Adhesion. International Journal of Molecular Sciences. 24. PMID 36901713 DOI: 10.3390/ijms24054274  0.31
2015 Craig SE, Brady-Kalnay SM. Regulation of development and cancer by the R2B subfamily of RPTPs and the implications of proteolysis. Seminars in Cell & Developmental Biology. 37: 108-18. PMID 25223585 DOI: 10.1016/j.semcdb.2014.09.004  0.422
2014 Phillips-Mason PJ, Craig SE, Brady-Kalnay SM. A protease storm cleaves a cell-cell adhesion molecule in cancer: multiple proteases converge to regulate PTPmu in glioma cells. Journal of Cellular Biochemistry. 115: 1609-23. PMID 24771611 DOI: 10.1002/jcb.24824  0.332
2012 Brady-Kalnay SM. Molecular mechanisms of cancer cell-cell interactions: cell-cell adhesion-dependent signaling in the tumor microenvironment. Cell Adhesion & Migration. 6: 344-5. PMID 22983192 DOI: 10.4161/cam.21489  0.31
2012 Kaur H, Burden-Gulley SM, Phillips-Mason PJ, Basilion JP, Sloan AE, Brady-Kalnay SM. Protein tyrosine phosphatase mu regulates glioblastoma cell growth and survival in vivo. Neuro-Oncology. 14: 561-73. PMID 22505657 DOI: 10.1093/neuonc/nos066  0.331
2011 Phillips-Mason PJ, Craig SE, Brady-Kalnay SM. Should I stay or should I go? Shedding of RPTPs in cancer cells switches signals from stabilizing cell-cell adhesion to driving cell migration. Cell Adhesion & Migration. 5: 298-305. PMID 21785275  0.459
2011 Craig SE, Brady-Kalnay SM. Tumor-derived extracellular fragments of receptor protein tyrosine phosphatases (RPTPs) as cancer molecular diagnostic tools. Anti-Cancer Agents in Medicinal Chemistry. 11: 133-40. PMID 21235433  0.314
2011 Craig SE, Brady-Kalnay SM. Cancer cells cut homophilic cell adhesion molecules and run. Cancer Research. 71: 303-9. PMID 21084269 DOI: 10.1158/0008-5472.CAN-10-2301  0.33
2011 Phillips-Mason PJ, Kaur H, Burden-Gulley SM, Craig SE, Brady-Kalnay SM. Identification of phospholipase C gamma1 as a protein tyrosine phosphatase mu substrate that regulates cell migration. Journal of Cellular Biochemistry. 112: 39-48. PMID 20506511 DOI: 10.1002/jcb.22710  0.407
2010 Becka S, Zhang P, Craig SE, Lodowski DT, Wang Z, Brady-Kalnay SM. Characterization of the adhesive properties of the type IIb subfamily receptor protein tyrosine phosphatases. Cell Communication & Adhesion. 17: 34-47. PMID 20521994 DOI: 10.3109/15419061.2010.487957  0.381
2010 Oblander SA, Brady-Kalnay SM. Distinct PTPmu-associated signaling molecules differentially regulate neurite outgrowth on E-, N-, and R-cadherin. Molecular and Cellular Neurosciences. 44: 78-93. PMID 20197094 DOI: 10.1016/j.mcn.2010.02.005  0.368
2009 Burgoyne AM, Phillips-Mason PJ, Burden-Gulley SM, Robinson S, Sloan AE, Miller RH, Brady-Kalnay SM. Proteolytic cleavage of protein tyrosine phosphatase mu regulates glioblastoma cell migration. Cancer Research. 69: 6960-8. PMID 19690139 DOI: 10.1158/0008-5472.Can-09-0863  0.361
2008 Phillips-Mason PJ, Mourton T, Major DL, Brady-Kalnay SM. BCCIP associates with the receptor protein tyrosine phosphatase PTPmu. Journal of Cellular Biochemistry. 105: 1059-72. PMID 18773424 DOI: 10.1002/jcb.21907  0.465
2007 Oblander SA, Ensslen-Craig SE, Longo FM, Brady-Kalnay SM. E-cadherin promotes retinal ganglion cell neurite outgrowth in a protein tyrosine phosphatase-mu-dependent manner. Molecular and Cellular Neurosciences. 34: 481-92. PMID 17276081 DOI: 10.1016/j.mcn.2006.12.002  0.35
2007 Major DL, Brady-Kalnay SM. Rho GTPases regulate PTPmu-mediated nasal neurite outgrowth and temporal repulsion of retinal ganglion cell neurons. Molecular and Cellular Neurosciences. 34: 453-67. PMID 17234431 DOI: 10.1016/j.mcn.2006.11.022  0.392
2006 Xie Y, Massa SM, Ensslen-Craig SE, Major DL, Yang T, Tisi MA, Derevyanny VD, Runge WO, Mehta BP, Moore LA, Brady-Kalnay SM, Longo FM. Protein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase function. The Journal of Biological Chemistry. 281: 16482-92. PMID 16613844 DOI: 10.1074/jbc.M603131200  0.301
2006 Phillips-Mason PJ, Gates TJ, Major DL, Sacks DB, Brady-Kalnay SM. The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1. The Journal of Biological Chemistry. 281: 4903-10. PMID 16380380 DOI: 10.1074/jbc.M506414200  0.442
2005 Ensslen-Craig SE, Brady-Kalnay SM. PTP mu expression and catalytic activity are required for PTP mu-mediated neurite outgrowth and repulsion. Molecular and Cellular Neurosciences. 28: 177-88. PMID 15607952 DOI: 10.1016/j.mcn.2004.08.011  0.49
2004 Ensslen-Craig SE, Brady-Kalnay SM. Receptor protein tyrosine phosphatases regulate neural development and axon guidance. Developmental Biology. 275: 12-22. PMID 15464569 DOI: 10.1016/j.ydbio.2004.08.009  0.389
2004 Jain A, Brady-Kalnay SM, Bellamkonda RV. Modulation of Rho GTPase activity alleviates chondroitin sulfate proteoglycan-dependent inhibition of neurite extension. Journal of Neuroscience Research. 77: 299-307. PMID 15211597 DOI: 10.1002/Jnr.20161  0.357
2004 Ensslen SE, Brady-Kalnay SM. PTPmu signaling via PKCdelta is instructive for retinal ganglion cell guidance. Molecular and Cellular Neurosciences. 25: 558-71. PMID 15080886 DOI: 10.1016/j.mcn.2003.12.003  0.541
2003 Chattopadhyay N, Wang Z, Ashman LK, Brady-Kalnay SM, Kreidberg JA. α3β1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPμ expression and cell-cell adhesion Journal of Cell Biology. 163: 1351-1362. PMID 14691142 DOI: 10.1083/jcb.200306067  0.328
2003 Ensslen SE, Rosdahl JA, Brady-Kalnay SM. The receptor protein tyrosine phosphatase mu, PTPmu, regulates histogenesis of the chick retina. Developmental Biology. 264: 106-18. PMID 14623235 DOI: 10.1016/J.Ydbio.2003.08.009  0.58
2003 Rosdahl JA, Ensslen SE, Niedenthal JA, Brady-Kalnay SM. PTP mu-dependent growth cone rearrangement is regulated by Cdc42. Journal of Neurobiology. 56: 199-208. PMID 12884260 DOI: 10.1002/Neu.10231  0.554
2002 Burden-Gulley SM, Ensslen SE, Brady-Kalnay SM. Protein tyrosine phosphatase-mu differentially regulates neurite outgrowth of nasal and temporal neurons in the retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3615-27. PMID 11978837  0.448
2002 Rosdahl JA, Mourton TL, Brady-Kalnay SM. Protein kinase C delta (PKCdelta) is required for protein tyrosine phosphatase mu (PTPmu)-dependent neurite outgrowth. Molecular and Cellular Neurosciences. 19: 292-306. PMID 11860281 DOI: 10.1006/Mcne.2001.1071  0.588
2002 Hellberg CB, Burden-Gulley SM, Pietz GE, Brady-Kalnay SM. Expression of the receptor protein-tyrosine phosphatase, PTPmu, restores E-cadherin-dependent adhesion in human prostate carcinoma cells. The Journal of Biological Chemistry. 277: 11165-73. PMID 11801604 DOI: 10.1074/jbc.M112157200  0.349
2001 Wong K, Ren XR, Huang YZ, Xie Y, Liu G, Saito H, Tang H, Wen L, Brady-Kalnay SM, Mei L, Wu JY, Xiong WC, Rao Y. Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway. Cell. 107: 209-21. PMID 11672528 DOI: 10.1016/S0092-8674(01)00530-X  0.369
2001 Mourton T, Hellberg CB, Burden-Gulley SM, Hinman J, Rhee A, Brady-Kalnay SM. The PTPμ Protein-tyrosine Phosphatase Binds and Recruits the Scaffolding Protein RACK1 to Cell-Cell Contacts Journal of Biological Chemistry. 276: 14896-14901. PMID 11278757 DOI: 10.1074/jbc.M010823200  0.444
1999 Burden-Gulley SM, Brady-Kalnay SM. PTPμ regulates N-cadherin-dependent neurite outgrowth Journal of Cell Biology. 144: 1323-1336. PMID 10087273 DOI: 10.1083/jcb.144.6.1323  0.49
1998 Brady-Kalnay SM, Mourton T, Nixon JP, Pietz GE, Kinch M, Chen H, Brackenbury R, Rimm DL, Del Vecchio RL, Tonks NK. Dynamic interaction of PTPmu with multiple cadherins in vivo. The Journal of Cell Biology. 141: 287-96. PMID 9531566 DOI: 10.1083/Jcb.141.1.287  0.31
1995 Brady-Kalnay SM, Tonks NK. Protein tyrosine phosphatases as adhesion receptors Current Opinion in Cell Biology. 7: 650-657. PMID 8573339 DOI: 10.1016/0955-0674(95)80106-5  0.474
1995 Brady-Kalnay SM, Rimm DL, Tonks NK. Receptor protein tyrosine phosphatase PTPμ associates with cadherins and catenins in vivo Journal of Cell Biology. 130: 977-986. PMID 7642713 DOI: 10.1083/Jcb.130.4.977  0.336
1994 Brady-Kalnay SM, Tonks NK. Protein tyrosine phosphatases: from structure to function Trends in Cell Biology. 4: 73-76. DOI: 10.1016/0962-8924(94)90172-4  0.355
1993 Brady-Kalnay SM, Flint AJ, Tonks NK. Homophilic binding of PTPμ, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation Journal of Cell Biology. 122: 961-972. PMID 8394372 DOI: 10.1083/Jcb.122.4.961  0.399
1993 Brady-Kalnay SM, Tonks NK. Purification and characterization of the human protein tyrosine phosphatase, PTPμ, from a baculovirus expression system Molecular and Cellular Biochemistry. 127: 131-141. PMID 7935345 DOI: 10.1007/Bf01076764  0.31
1992 Tonks NK, Yang Q, Flint AJ, Gebbink MFBG, Franza BR, Hill DE, Sun H, Brady-Kalnay S. Protein tyrosine phosphatases: The problems of a growing family Cold Spring Harbor Symposia On Quantitative Biology. 57: 87-94. PMID 1339708 DOI: 10.1101/Sqb.1992.057.01.012  0.363
1991 Brady-Kalnay SM, Soll DR, Brackenbury R. Invasion of Rous sarcoma virus-transformed retinal cells: Role of cell motility International Journal of Cancer. 47: 560-568. PMID 1847356 DOI: 10.1002/Ijc.2910470414  0.313
1991 Brady-Kalnay SM, Boghaert ER, Zimmer S, Soll DR, Brackenbury R. Invasion by WC5 rat cerebellar cells is independent of RSV-induced changes in growth and adhesion. International Journal of Cancer. 49: 239-45. PMID 1652569 DOI: 10.1002/Ijc.2910490217  0.313
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