Kelley W. Moremen - Publications

Affiliations: 
University of Georgia, Athens, Athens, GA, United States 
Area:
Biochemistry, Molecular Biology

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rogals MJ, Yang JY, Williams RV, Moremen KW, Amster IJ, Prestegard JH. Sparse isotope labeling for nuclear magnetic resonance (NMR) of glycoproteins using 13C-glucose. Glycobiology. PMID 32902634 DOI: 10.1093/Glycob/Cwaa071  0.333
2020 Prabhakar PK, Wang HT, Smith PJ, Yang JY, Barnes WJ, Peña MJ, Moremen KW, Urbanowicz BR. Heterologous expression of plant glycosyltransferases for biochemistry and structural biology. Methods in Cell Biology. 160: 145-165. PMID 32896313 DOI: 10.1016/Bs.Mcb.2020.05.002  0.314
2020 Lunin V, Wang HT, Bharadwaj V, Alahuhta PM, Pena MJ, Yang JY, Archer-Hartmann SA, Azadi P, Himmel M, Moremen KW, York WS, Bomble YJ, Urbanowicz B. Molecular mechanism of polysaccharide acetylation by the Arabidopsis xylan O-acetyltransferase XOAT1. The Plant Cell. PMID 32354790 DOI: 10.1105/Tpc.20.00028  0.303
2020 Zhuo Y, Yang JY, Moremen KW, Prestegard JH. Correction: Glycosylation alters dimerization properties of a cell-surface signaling protein, carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1). The Journal of Biological Chemistry. 295: 3748. PMID 32169858 DOI: 10.1074/Jbc.Aac120.013039  0.368
2020 Sheikh MO, Venzke D, Anderson ME, Yoshida-Moriguchi T, Glushka JN, Nairn AV, Galizzi M, Moremen KW, Campbell KP, Wells L. HNK-1 Sulfotransferase modulates α-dystroglycan glycosylation by 3-O-sulfation of glucuronic acid on matriglycan. Glycobiology. PMID 32149355 DOI: 10.1093/Glycob/Cwaa024  0.333
2020 Saeui CT, Cho KC, Dharmarha V, Nairn AV, Galizzi M, Shah SR, Gowda P, Park M, Austin M, Clarke A, Cai E, Buettner MJ, Ariss R, Moremen KW, Zhang H, et al. Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression. Frontiers in Chemistry. 8: 13. PMID 32117864 DOI: 10.3389/Fchem.2020.00013  0.361
2019 Moremen KW, Haltiwanger RS. Emerging structural insights into glycosyltransferase-mediated synthesis of glycans. Nature Chemical Biology. 15: 853-864. PMID 31427814 DOI: 10.1038/S41589-019-0350-2  0.336
2019 't Hart IME, Li T, Wolfert MA, Wang S, Moremen KW, Boons GJ. Chemoenzymatic synthesis of the oligosaccharide moiety of the tumor-associated antigen disialosyl globopentaosylceramide. Organic & Biomolecular Chemistry. PMID 31339142 DOI: 10.1039/C9Ob01368G  0.314
2019 Steentoft C, Yang Z, Wang S, Ju T, Vester-Christensen MB, Festari MF, King SL, Moremen K, Larsen ISB, Goth CK, Schjoldager KT, Hansen L, Bennett EP, Mandel U, Narimatsu Y. A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-Glycosylation. Glycobiology. PMID 31172184 DOI: 10.1093/Glycob/Cwz041  0.381
2019 Chalmers GR, Eletsky A, Morris LC, Yang JY, Tian F, Woods RJ, Moremen KW, Prestegard JH. NMR Resonance Assignment Methodology: Characterizing Large Sparsely Labeled Glycoproteins. Journal of Molecular Biology. PMID 31034888 DOI: 10.1016/J.Jmb.2019.04.029  0.323
2019 Chinoy ZS, Bodineau C, Favre C, Moremen KW, Durán RV, Friscourt F. Selective Engineering of Linkage Specific α2,6-N-Linked Sialoproteins using Sydnone-Modified Sialic Acid Bioorthogonal Reporters. Angewandte Chemie (International Ed. in English). PMID 30706985 DOI: 10.1002/Anie.201814266  0.303
2018 Li J, Chen M, Liu Z, Zhang L, Felding BH, Moremen KW, Lauvau G, Abadier M, Ley K, Wu P. A Single-Step Chemoenzymatic Reaction for the Construction of Antibody-Cell Conjugates. Acs Central Science. 4: 1633-1641. PMID 30648147 DOI: 10.1021/Acscentsci.8B00552  0.342
2018 Liu L, Prudden AR, Capicciotti CJ, Bosman GP, Yang JY, Chapla DG, Moremen KW, Boons GJ. Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy. Nature Chemistry. PMID 30532014 DOI: 10.1038/S41557-018-0188-3  0.309
2018 Qiu H, Shi S, Yue J, Xin M, Nairn AV, Lin L, Liu X, Li G, Archer-Hartmann SA, Dela Rosa M, Galizzi M, Wang S, Zhang F, Azadi P, van Kuppevelt TH, ... ... Moremen KW, et al. A mutant-cell library for systematic analysis of heparan sulfate structure-function relationships. Nature Methods. PMID 30377379 DOI: 10.1038/S41592-018-0189-6  0.375
2018 Amos RA, Pattathil S, Yang JY, Atmodjo MA, Urbanowicz BR, Moremen KW, Mohnen D. A two-phase model for the non-processive biosynthesis of homogalacturonan polysaccharides by the GAUT1:GAUT7 complex. The Journal of Biological Chemistry. PMID 30327429 DOI: 10.1074/Jbc.Ra118.004463  0.314
2018 Voiniciuc C, Engle KA, Günl M, Dieluweit S, Schmidt MH, Yang JY, Moremen KW, Mohnen D, Usadel B. Identification of Key Enzymes for Pectin Synthesis in Seed Mucilage. Plant Physiology. PMID 30228108 DOI: 10.1104/Pp.18.00584  0.337
2018 Thieker DF, Xu Y, Chapla D, Nora C, Qiu H, Felix T, Wang L, Moremen KW, Liu J, Esko JD, Woods RJ. Downstream Products are Potent Inhibitors of the Heparan Sulfate 2-O-Sulfotransferase. Scientific Reports. 8: 11832. PMID 30087361 DOI: 10.1038/S41598-018-29602-4  0.318
2018 Moure MJ, Eletsky A, Gao Q, Morris LC, Yang JY, Chapla D, Zhao Y, Zong C, Amster IJ, Moremen KW, Boons GJ, Prestegard JH. Paramagnetic Tag for Glycosylation sites in Glycoproteins: Structural Constraints on Heparan Sulfate Binding to Robo1. Acs Chemical Biology. PMID 30063822 DOI: 10.1021/Acschembio.8B00511  0.349
2018 Yu SH, Zhao P, Prabhakar PK, Sun T, Beedle A, Boons GJ, Moremen KW, Wells L, Steet R. Defective mucin-type glycosylation on α-dystroglycan in COG-deficient cells increases its susceptibility to bacterial proteases. The Journal of Biological Chemistry. PMID 30049793 DOI: 10.1074/Jbc.Ra118.003014  0.38
2018 Saeui CT, Nairn AV, Galizzi M, Douville C, Gowda P, Park M, Dharmarha V, Shah SR, Clarke A, Austin M, Moremen KW, Yarema KJ. Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes. Plos One. 13: e0195812. PMID 29847599 DOI: 10.1371/Journal.Pone.0195812  0.313
2018 Kadirvelraj R, Yang JY, Sanders JH, Liu L, Ramiah A, Prabhakar PK, Boons GJ, Wood ZA, Moremen KW. Human -acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite. Proceedings of the National Academy of Sciences of the United States of America. PMID 29666272 DOI: 10.1073/Pnas.1716988115  0.346
2018 Gao Q, Yang JY, Moremen KW, Flanagan JG, Prestegard JH. Structural Characterization of a Heparan Sulfate Pentamer Interacting with LAR-Ig1-2. Biochemistry. PMID 29570275 DOI: 10.1021/Acs.Biochem.8B00241  0.351
2018 Briard JG, Jiang H, Moremen KW, Macauley MS, Wu P. Cell-based glycan arrays for probing glycan-glycan binding protein interactions. Nature Communications. 9: 880. PMID 29491407 DOI: 10.1038/S41467-018-03245-5  0.346
2018 Rouhanifard SH, Lopez Aguilar A, Meng L, Moremen KW, Wu P. Engineered Glycocalyx Regulates Stem Cell Proliferation in Murine Crypt Organoids. Cell Chemical Biology. PMID 29429899 DOI: 10.1016/J.Chembiol.2018.01.010  0.376
2017 Moremen KW, Ramiah A, Stuart M, Steel J, Meng L, Forouhar F, Moniz HA, Gahlay G, Gao Z, Chapla D, Wang S, Yang JY, Prabhakar PK, Johnson R, Rosa MD, et al. Expression system for structural and functional studies of human glycosylation enzymes. Nature Chemical Biology. PMID 29251719 DOI: 10.1038/Nchembio.2539  0.351
2017 Urbanowicz BR, Bharadwaj VS, Alahuhta M, Peña MJ, Lunin VV, Bomble YJ, Wang S, Yang JY, Tuomivaara ST, Himmel ME, Moremen KW, York WS, Crowley MF. Structural, Mutagenic and In Silico studies of Xyloglucan Fucosylation in Arabidopsis thaliana Suggest a Water-Mediated Mechanism. The Plant Journal : For Cell and Molecular Biology. PMID 28670741 DOI: 10.1111/Tpj.13628  0.332
2017 Hanes MS, Moremen KW, Cummings RD. Biochemical characterization of functional domains of the chaperone Cosmc. Plos One. 12: e0180242. PMID 28665962 DOI: 10.1371/Journal.Pone.0180242  0.35
2017 Prudden AR, Liu L, Capicciotti CJ, Wolfert MA, Wang S, Gao Z, Meng L, Moremen KW, Boons GJ. Synthesis of asymmetrical multiantennary human milk oligosaccharides. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630345 DOI: 10.1073/Pnas.1701785114  0.341
2017 Guo H, Zhang B, Nairn AV, Nagy T, Moremen KW, Buckhaults P, Pierce M. O-GlcNAc expression levels epigenetically regulate colon cancer tumorigenesis by affecting the cancer stem cell compartment via modulating expression of transcriptional factor MYBL1. The Journal of Biological Chemistry. PMID 28096468 DOI: 10.1074/Jbc.M116.763201  0.327
2016 Halmo SM, Singh D, Patel S, Wang S, Edlin M, Boons GJ, Moremen KW, Live D, Wells L. Protein O-linked mannose β-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2) is a gatekeeper enzyme for functional glycosylation of α-dystroglycan. The Journal of Biological Chemistry. PMID 27932460 DOI: 10.1074/Jbc.M116.764712  0.338
2016 Xiang Y, Karaveg K, Moremen KW. Substrate recognition and catalysis by GH47 α-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 27856750 DOI: 10.1073/Pnas.1611213113  0.35
2016 Gao Q, Chen CY, Zong C, Wang S, Ramiah A, Prabhakar P, Morris LC, Boons GJ, Moremen KW, Prestegard JH. Structural Aspects of Heparan Sulfate Binding to Robo1-Ig1-2. Acs Chemical Biology. PMID 27653286 DOI: 10.1021/Acschembio.6B00692  0.333
2016 Zong C, Huang R, Condac E, Chiu Y, Xiao W, Li X, Lu W, Ishahara M, Wang S, Ramiah A, Stickney M, Azadi P, Amster IJ, Moremen KW, Wang L, et al. An Integrated Approach to Identify Heparan Sulfate Ligand Requirements of Robo1. Journal of the American Chemical Society. PMID 27611601 DOI: 10.1021/Jacs.6B08161  0.307
2016 Sun T, Yu SH, Zhao P, Meng L, Moremen KW, Wells L, Steet R, Boons GJ. A One-step Selective Exo-enzymatic Labeling (SEEL) Strategy for the Biotinylation and Identification of Glycoproteins of Living Cells. Journal of the American Chemical Society. PMID 27541995 DOI: 10.1021/Jacs.6B04049  0.303
2016 Zhuo Y, Yang JY, Moremen KW, Prestegard JH. Glycosylation alters dimerization properties of a cell-surface signaling protein, CEACAM1. The Journal of Biological Chemistry. PMID 27471271 DOI: 10.1074/Jbc.M116.740050  0.364
2016 Deligny A, Dierker T, Dagälv A, Lundequist A, Eriksson I, Nairn AV, Moremen KW, Merry CL, Kjellen L. NDST2 (N-Deacetylase/N-Sulfotransferase-2) Regulates Heparan Sulfate Chain Length. The Journal of Biological Chemistry. PMID 27387504 DOI: 10.1074/Jbc.M116.744433  0.384
2016 Zhang C, Zhang T, Zou J, Miller CL, Gorkhali R, Yang JY, Schilmiller A, Wang S, Huang K, Brown EM, Moremen KW, Hu J, Yang JJ. Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist. Science Advances. 2: e1600241. PMID 27386547 DOI: 10.1126/Sciadv.1600241  0.311
2016 McMorran BJ, McCarthy FE, Gibbs EM, Pang M, Marshall JL, Nairn AV, Moremen KW, Crosbie-Watson RH, Baum LG. Differentiation-related glycan epitopes identify discrete domains of the muscle glycocalyx. Glycobiology. PMID 27236198 DOI: 10.1093/Glycob/Cww061  0.316
2016 Praissman JL, Willer T, Sheikh MO, Toi A, Chitayat D, Lin YY, Lee H, Stalnaker SH, Wang S, Prabhakar PK, Nelson SF, Stemple DL, Moore SA, Moremen KW, Campbell KP, et al. The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition. Elife. 5. PMID 27130732 DOI: 10.7554/Elife.14473  0.342
2016 Berger RP, Sun YH, Kulik M, Lee JK, Nairn AV, Moremen KW, Pierce M, Dalton S. ST8SIA4 Dependent Polysialylation is Part of a Developmental program Required for Germ Layer Formation from Human Pluripotent Stem Cells. Stem Cells (Dayton, Ohio). PMID 27074314 DOI: 10.1002/Stem.2379  0.394
2016 Yu SH, Zhao P, Sun T, Gao Z, Moremen KW, Boons GJ, Wells L, Steet R. Selective exo-enzymatic labeling detects increased cell surface sialoglycoprotein expression upon megakaryocytic differentiation. The Journal of Biological Chemistry. PMID 26733198 DOI: 10.1074/Jbc.M115.700369  0.36
2015 Subedi GP, Johnson RW, Moniz HA, Moremen KW, Barb A. High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension. Journal of Visualized Experiments : Jove. PMID 26779721 DOI: 10.3791/53568  0.368
2015 Zhou T, Frabutt DA, Moremen KW, Zheng YH. ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway. The Journal of Biological Chemistry. 290: 22184-92. PMID 26205822 DOI: 10.1074/Jbc.M115.675207  0.326
2015 Li Z, Moniz H, Wang S, Ramiah A, Zhang F, Moremen KW, Linhardt RJ, Sharp JS. High structural resolution hydroxyl radical protein footprinting reveals an extended Robo1-heparin binding interface. The Journal of Biological Chemistry. 290: 10729-40. PMID 25752613 DOI: 10.1074/Jbc.M115.648410  0.308
2014 Zhang C, Zhuo Y, Moniz HA, Wang S, Moremen KW, Prestegard JH, Brown EM, Yang JJ. Direct determination of multiple ligand interactions with the extracellular domain of the calcium-sensing receptor. The Journal of Biological Chemistry. 289: 33529-42. PMID 25305020 DOI: 10.1074/Jbc.M114.604652  0.313
2014 Praissman JL, Live DH, Wang S, Ramiah A, Chinoy ZS, Boons GJ, Moremen KW, Wells L. B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan. Elife. 3. PMID 25279697 DOI: 10.7554/Elife.03943  0.331
2014 Gasimli L, Hickey AM, Yang B, Li G, dela Rosa M, Nairn AV, Kulik MJ, Dordick JS, Moremen KW, Dalton S, Linhardt RJ. Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages. Biochimica Et Biophysica Acta. 1840: 1993-2003. PMID 24412195 DOI: 10.1016/J.Bbagen.2014.01.007  0.376
2013 Meng L, Forouhar F, Thieker D, Gao Z, Ramiah A, Moniz H, Xiang Y, Seetharaman J, Milaninia S, Su M, Bridger R, Veillon L, Azadi P, Kornhaber G, Wells L, ... ... Moremen KW, et al. Enzymatic basis for N-glycan sialylation: structure of rat α2,6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation. The Journal of Biological Chemistry. 288: 34680-98. PMID 24155237 DOI: 10.1074/Jbc.M113.519041  0.357
2013 Mbua NE, Li X, Flanagan-Steet HR, Meng L, Aoki K, Moremen KW, Wolfert MA, Steet R, Boons GJ. Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I. Angewandte Chemie (International Ed. in English). 52: 13012-5. PMID 24129959 DOI: 10.1002/Anie.201307095  0.325
2013 Moremen KW. The 2013 Karl Meyer Award and Rosalind Kornfeld Award from the Society for Glycobiology. Glycobiology. 23: 1207-9. PMID 24127495 DOI: 10.1093/Glycob/Cwu099  0.31
2013 Zhang F, Moniz HA, Walcott B, Moremen KW, Linhardt RJ, Wang L. Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans. Biochimie. 95: 2345-53. PMID 23994753 DOI: 10.1016/J.Biochi.2013.08.018  0.307
2013 Natunen S, Lampinen M, Suila H, Ritamo I, Pitkänen V, Nairn AV, Räbinä J, Laitinen S, Moremen KW, Reutter W, Valmu L. Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine. Glycobiology. 23: 1004-12. PMID 23708401 DOI: 10.1093/Glycob/Cwt039  0.377
2013 Gerken TA, Revoredo L, Thome JJ, Tabak LA, Vester-Christensen MB, Clausen H, Gahlay GK, Jarvis DL, Johnson RW, Moniz HA, Moremen K. The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation. The Journal of Biological Chemistry. 288: 19900-14. PMID 23689369 DOI: 10.1074/Jbc.M113.477877  0.313
2013 Gasimli L, Stansfield HE, Nairn AV, Liu H, Paluh JL, Yang B, Dordick JS, Moremen KW, Linhardt RJ. Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells Glycoconjugate Journal. 30: 497-510. PMID 23053635 DOI: 10.1007/S10719-012-9450-X  0.39
2013 Zhang C, Zhuo Y, Feng J, Strachan H, Mulpuri N, Hamelberg D, Moremen K, Brown EM, Yang JJ. Hetero Interaction with an Amino Acid Globally Enhances Cooperative Activation of CaSR in Response to Extracellular Signaling Biophysical Journal. 104: 402a-403a. DOI: 10.1016/J.Bpj.2012.11.2246  0.3
2012 Nairn AV, Aoki K, dela Rosa M, Porterfield M, Lim JM, Kulik M, Pierce JM, Wells L, Dalton S, Tiemeyer M, Moremen KW. Regulation of glycan structures in murine embryonic stem cells: combined transcript profiling of glycan-related genes and glycan structural analysis. The Journal of Biological Chemistry. 287: 37835-56. PMID 22988249 DOI: 10.1074/Jbc.M112.405233  0.42
2012 Moremen KW, Tiemeyer M, Nairn AV. Vertebrate protein glycosylation: diversity, synthesis and function. Nature Reviews. Molecular Cell Biology. 13: 448-62. PMID 22722607 DOI: 10.1038/Nrm3383  0.301
2012 Guo H, Nairn A, dela Rosa M, Nagy T, Zhao S, Moremen K, Pierce M. Transcriptional regulation of the protocadherin β cluster during Her-2 protein-induced mammary tumorigenesis results from altered N-glycan branching. The Journal of Biological Chemistry. 287: 24941-54. PMID 22665489 DOI: 10.1074/Jbc.M112.369355  0.728
2012 Condac E, Strachan H, Gutierrez-Sanchez G, Brainard B, Giese C, Heiss C, Johnson D, Azadi P, Bergmann C, Orlando R, Esmon CT, Harenberg J, Moremen K, Wang L. The C-terminal fragment of axon guidance molecule Slit3 binds heparin and neutralizes heparin's anticoagulant activity. Glycobiology. 22: 1183-92. PMID 22641771 DOI: 10.1093/Glycob/Cws087  0.303
2012 Barb AW, Meng L, Gao Z, Johnson RW, Moremen KW, Prestegard JH. NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation. Biochemistry. 51: 4618-26. PMID 22574931 DOI: 10.1021/Bi300319Q  0.338
2012 Kraushaar DC, Rai S, Condac E, Nairn A, Zhang S, Yamaguchi Y, Moremen K, Dalton S, Wang L. Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells. The Journal of Biological Chemistry. 287: 22691-700. PMID 22556407 DOI: 10.1074/Jbc.M112.368241  0.728
2012 Petrey AC, Flanagan-Steet H, Johnson S, Fan X, De la Rosa M, Haskins ME, Nairn AV, Moremen KW, Steet R. Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II. Disease Models & Mechanisms. 5: 177-90. PMID 22046029 DOI: 10.1242/Dmm.008219  0.304
2012 Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Moremen K, ... ... Moremen KW, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127  0.721
2011 Pan S, Wang S, Utama B, Huang L, Blok N, Estes MK, Moremen KW, Sifers RN. Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system. Molecular Biology of the Cell. 22: 2810-22. PMID 21697506 DOI: 10.1091/Mbc.E11-02-0118  0.348
2010 Nairn AV, dela Rosa M, Moremen KW. Transcript analysis of stem cells. Methods in Enzymology. 479: 73-91. PMID 20816160 DOI: 10.1016/S0076-6879(10)79004-2  0.305
2009 Liu S, Meng L, Moremen KW, Prestegard JH. Nuclear magnetic resonance structural characterization of substrates bound to the alpha-2,6-sialyltransferase, ST6Gal-I. Biochemistry. 48: 11211-9. PMID 19845399 DOI: 10.1021/Bi9015154  0.319
2009 Orlando R, Lim JM, Atwood JA, Angel PM, Fang M, Aoki K, Alvarez-Manilla G, Moremen KW, York WS, Tiemeyer M, Pierce M, Dalton S, Wells L. IDAWG: Metabolic incorporation of stable isotope labels for quantitative glycomics of cultured cells. Journal of Proteome Research. 8: 3816-23. PMID 19449840 DOI: 10.1021/Pr8010028  0.327
2009 Termine DJ, Moremen KW, Sifers RN. The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I. Journal of Cell Science. 122: 976-84. PMID 19258393 DOI: 10.1242/Jcs.037291  0.344
2008 Macnaughtan MA, Tian F, Liu S, Meng L, Park S, Azadi P, Moremen KW, Prestegard JH. 13C-sialic acid labeling of glycans on glycoproteins using ST6Gal-I. Journal of the American Chemical Society. 130: 11864-5. PMID 18700760 DOI: 10.1021/Ja804614W  0.34
2008 Abbott KL, Nairn AV, Hall EM, Horton MB, McDonald JF, Moremen KW, Dinulescu DM, Pierce M. Focused glycomic analysis of the N-linked glycan biosynthetic pathway in ovarian cancer. Proteomics. 8: 3210-20. PMID 18690643 DOI: 10.1002/Pmic.200800157  0.311
2008 Zhong W, Kuntz DA, Ember B, Singh H, Moremen KW, Rose DR, Boons GJ. Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. Journal of the American Chemical Society. 130: 8975-83. PMID 18558690 DOI: 10.1021/Ja711248Y  0.336
2008 Nairn AV, York WS, Harris K, Hall EM, Pierce JM, Moremen KW. Regulation of glycan structures in animal tissues: transcript profiling of glycan-related genes. The Journal of Biological Chemistry. 283: 17298-313. PMID 18411279 DOI: 10.1074/Jbc.M801964200  0.383
2008 Guo HB, Nairn A, Harris K, Randolph M, Alvarez-Manilla G, Moremen K, Pierce M. Loss of expression of N-acetylglucosaminyltransferase Va results in altered gene expression of glycosyltransferases and galectins. Febs Letters. 582: 527-35. PMID 18230362 DOI: 10.1016/J.Febslet.2008.01.015  0.73
2007 Nairn AV, Kinoshita-Toyoda A, Toyoda H, Xie J, Harris K, Dalton S, Kulik M, Pierce JM, Toida T, Moremen KW, Linhardt RJ. Glycomics of proteoglycan biosynthesis in murine embryonic stem cell differentiation. Journal of Proteome Research. 6: 4374-87. PMID 17915907 DOI: 10.1021/Pr070446F  0.399
2007 Wu Y, Termine DJ, Swulius MT, Moremen KW, Sifers RN. Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis. The Journal of Biological Chemistry. 282: 4841-9. PMID 17166854 DOI: 10.1074/Jbc.M607156200  0.349
2006 Mast SW, Moremen KW. Family 47 alpha-mannosidases in N-glycan processing. Methods in Enzymology. 415: 31-46. PMID 17116466 DOI: 10.1016/S0076-6879(06)15003-X  0.302
2006 Moremen KW, Molinari M. N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control. Current Opinion in Structural Biology. 16: 592-9. PMID 16938451 DOI: 10.1016/J.Sbi.2006.08.005  0.34
2006 Akama TO, Nakagawa H, Wong NK, Sutton-Smith M, Dell A, Morris HR, Nakayama J, Nishimura S, Pai A, Moremen KW, Marth JD, Fukuda MN. Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 8983-8. PMID 16754854 DOI: 10.1073/Pnas.0603248103  0.371
2005 Park C, Meng L, Stanton LH, Collins RE, Mast SW, Yi X, Strachan H, Moremen KW. Characterization of a human core-specific lysosomal {alpha}1,6-mannosidase involved in N-glycan catabolism. The Journal of Biological Chemistry. 280: 37204-16. PMID 16115860 DOI: 10.1074/Jbc.M508930200  0.313
2005 Karaveg K, Moremen KW. Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control. The Journal of Biological Chemistry. 280: 29837-48. PMID 15911611 DOI: 10.1074/Jbc.M505130200  0.343
2005 Karaveg K, Siriwardena A, Tempel W, Liu ZJ, Glushka J, Wang BC, Moremen KW. Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control. The Journal of Biological Chemistry. 280: 16197-207. PMID 15713668 DOI: 10.1074/Jbc.M500119200  0.333
2005 Mast SW, Diekman K, Karaveg K, Davis A, Sifers RN, Moremen KW. Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins. Glycobiology. 15: 421-36. PMID 15537790 DOI: 10.1093/Glycob/Cwi014  0.317
2004 Tempel W, Karaveg K, Liu ZJ, Rose J, Wang BC, Moremen KW. Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases. The Journal of Biological Chemistry. 279: 29774-86. PMID 15102839 DOI: 10.1074/Jbc.M403065200  0.336
2003 Wu Y, Swulius MT, Moremen KW, Sifers RN. Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation. Proceedings of the National Academy of Sciences of the United States of America. 100: 8229-34. PMID 12815101 DOI: 10.1073/Pnas.1430537100  0.355
2002 Moremen KW. Golgi alpha-mannosidase II deficiency in vertebrate systems: implications for asparagine-linked oligosaccharide processing in mammals. Biochimica Et Biophysica Acta. 1573: 225-35. PMID 12417404 DOI: 10.1016/S0304-4165(02)00388-4  0.387
2002 Cabral CM, Liu Y, Moremen KW, Sifers RN. Organizational diversity among distinct glycoprotein endoplasmic reticulum-associated degradation programs. Molecular Biology of the Cell. 13: 2639-50. PMID 12181335 DOI: 10.1091/Mbc.E02-02-0068  0.38
2002 Akama TO, Nakagawa H, Sugihara K, Narisawa S, Ohyama C, Nishimura S, O'Brien DA, Moremen KW, Millan JL, Fukuda MN. Germ cell survival through carbohydrate-mediated interaction with Sertoli cells. Science (New York, N.Y.). 295: 124-7. PMID 11778047 DOI: 10.1126/Science.1065570  0.394
2001 Kawar Z, Karaveg K, Moremen KW, Jarvis DL. Insect Cells Encode a Class II α-Mannosidase with Unique Properties Journal of Biological Chemistry. 276: 16335-16340. PMID 11279010 DOI: 10.1074/Jbc.M100119200  0.324
2001 Oh-eda M, Nakagawa H, Akama TO, Lowitz K, Misago M, Moremen KW, Fukuda MN. Overexpression of the Golgi-localized enzyme α-mannosidase IIx in Chinese hamster ovary cells results in the conversion of hexamannosyl-N-acetylchitobiose to tetramannosyl-N-acetylchitobiose in the N-glycan-processing pathway European Journal of Biochemistry. 268: 1280-1288. PMID 11231279 DOI: 10.1046/J.1432-1327.2001.01992.X  0.332
2001 Lee JK, Schnee J, Pang M, Wolfert M, Baum LG, Moremen KW, Pierce M. Human homologs of the Xenopus oocyte cortical granule lectin XL35 Glycobiology. 11: 65-73. PMID 11181563 DOI: 10.1093/Glycob/11.1.65  0.348
2001 Rivera-Marrero CA, Ritzenthaler JD, Roman J, Moremen KW. Molecular cloning and expression of an alpha-mannosidase gene in Mycobacterium tuberculosis. Microbial Pathogenesis. 30: 9-18. PMID 11162181 DOI: 10.1006/Mpat.2000.0407  0.34
2000 Vallee F, Karaveg K, Herscovics A, Moremen KW, Howell PL. Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases. The Journal of Biological Chemistry. 275: 41287-98. PMID 10995765 DOI: 10.1074/Jbc.M006927200  0.345
1999 Igdoura SA, Herscovics A, Lal A, Moremen KW, Morales CR, Hermo L. α-mannosidases involved in N-glycan processing show cell specificity and distinct subcompartmentalization within the Golgi apparatus of cells in the testis and epididymis European Journal of Cell Biology. 78: 441-452. PMID 10472797 DOI: 10.1016/S0171-9335(99)80071-5  0.347
1999 Gonzalez DS, Karaveg K, Vandersall-Nairn AS, Lal A, Moremen KW. Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis Journal of Biological Chemistry. 274: 21375-21386. PMID 10409699 DOI: 10.1074/Jbc.274.30.21375  0.38
1999 Virgilio SD, Glushka J, Moremen K, Pierce M. Enzymatic Synthesis Of Natural And 13C Enriched Linear Poly-N-Acetyllactosamines As Ligands For Galectin-1 Glycobiology. 9: 353-364. PMID 10089209 DOI: 10.1093/Glycob/9.4.353  0.325
1998 Vandersall-Nairn AS, Merkle RK, O'Brien K, Oeltmann TN, Moremen KW. Cloning, expression, purification, and characterization of the acid α-mannosidase from Trypanosoma cruzi Glycobiology. 8: 1183-1194. PMID 9858640 DOI: 10.1093/Glycob/8.12.1183  0.33
1998 Lal A, Pang P, Kalelkar S, Romero PA, Herscovics A, Moremen KW. Substrate specificities of recombinant murine Golgi alpha1, 2-mannosidases IA and IB and comparison with endoplasmic reticulum and Golgi processing alpha1,2-mannosidases. Glycobiology. 8: 981-95. PMID 9719679 DOI: 10.1093/Glycob/8.10.981  0.334
1997 Howard S, Braun C, McCarter J, Moremen KW, Liao YF, Withers SG. Human lysosomal and jack bean α-mannosidases are retaining glycosidases Biochemical and Biophysical Research Communications. 238: 896-898. PMID 9325188 DOI: 10.1006/Bbrc.1997.7148  0.301
1997 Merkle RK, Zhang Y, Ruest PJ, Lal A, Liao YF, Moremen KW. Cloning, expression, purification, and characterization of the murine lysosomal acid α-mannosidase ' Biochimica Et Biophysica Acta - General Subjects. 1336: 132-146. PMID 9305783 DOI: 10.1016/S0304-4165(97)00023-8  0.339
1997 Chui D, Oh-Eda M, Liao YF, Panneerselvam K, Lal A, Marek KW, Freeze HH, Moremen KW, Fukuda MN, Marth JD. Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis. Cell. 90: 157-67. PMID 9230311 DOI: 10.1016/S0092-8674(00)80322-0  0.34
1997 Lee JK, Buckhaults P, Wilkes C, Teilhet M, King ML, Moremen KW, Pierce M. Cloning and expression of a Xenopus laevis oocyte lectin and characterization of its mRNA levels during early development. Glycobiology. 7: 367-72. PMID 9147045 DOI: 10.1093/Glycob/7.3.367  0.351
1997 Jarvis DL, Bohlmeyer DA, Liao YF, Lomax KK, Merkle RK, Weinkauf C, Moremen KW. Isolation and characterization of a class II α-mannosidase cDNA from lepidopteran insect cells Glycobiology. 7: 113-127. PMID 9061370 DOI: 10.1093/Glycob/7.1.113  0.367
1996 Liao YF, Lal A, Moremen KW. Cloning, expression, purification, and characterization of the human broad specificity lysosomal acid α-mannosidase Journal of Biological Chemistry. 271: 28348-28358. PMID 8910458 DOI: 10.1074/Jbc.271.45.28348  0.343
1995 Misago M, Liao YF, Kudo S, Eto S, Mattei MG, Moremen KW, Fukuda MN. Molecular cloning and expression of cDNAs encoding human α-mannosidase II and a previously unrecognized α-mannosidase IIX isozyme Proceedings of the National Academy of Sciences of the United States of America. 92: 11766-11770. PMID 8524845 DOI: 10.1073/Pnas.92.25.11766  0.302
1995 Prieto PA, Mukerji P, Kelder B, Erney R, Gonzalez D, Yun JS, Smith DF, Moremen KW, Nardelli C, Pierce M. Remodeling of mouse milk glycoconjugates by transgenic expression of a human glycosyltransferase. The Journal of Biological Chemistry. 270: 29515-9. PMID 7493992 DOI: 10.1074/Jbc.270.49.29515  0.336
1993 Sasisekharan R, Bulmer M, Moremen KW, Cooney CL, Langer R. Cloning and expression of heparinase I gene from Flavobacterium heparinum Proceedings of the National Academy of Sciences of the United States of America. 90: 3660-3664. PMID 8475114 DOI: 10.1073/Pnas.90.8.3660  0.314
1993 Abeijon C, Yanagisawa K, Mandon EC, Häusler A, Moremen K, Hirschberg CB, Robbins PW. Guanosine diphosphatase is required for protein and sphingolipid glycosylation in the Golgi lumen of Saccharomyces cerevisiae Journal of Cell Biology. 122: 307-323. PMID 8391537 DOI: 10.1083/Jcb.122.2.307  0.559
1993 Velasco A, Hendricks L, Moremen KW, Tulsiani DRP, Touster O, Farquhar MG. Cell type-dependent variations in the subcellular distribution of α-mannosidase I and II Journal of Cell Biology. 122: 39-51. PMID 8314846 DOI: 10.1083/jcb.122.1.39  0.575
1993 Herscovics A, Schneikert J, Athanassiadis A, Moremen KW, Robbins PW. S2.25 Isolation of a mouse cDNA encoding a processing mannosidase Glycoconjugate Journal. 10: 240-240. DOI: 10.1007/Bf01209868  0.511
1991 Moremen KW, Touster O, Robbins PW. Novel purification of the catalytic domain of Golgi alpha-mannosidase II. Characterization and comparison with the intact enzyme. The Journal of Biological Chemistry. 266: 16876-85. PMID 1885615  0.668
1991 Moremen KW, Robbins PW. Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans. The Journal of Cell Biology. 115: 1521-34. PMID 1757461 DOI: 10.1083/Jcb.115.6.1521  0.567
1986 Moremen KW, Touster O. Topology of mannosidase II in rat liver Golgi membranes and release of the catalytic domain by selective proteolysis Journal of Biological Chemistry. 261: 10945-10951. PMID 3733740  0.55
1985 Moremen KW, Touster O. Biosynthesis and modification of Golgi mannosidase II in HeLa and 3T3 cells Journal of Biological Chemistry. 260: 6654-6662. PMID 3922977  0.54
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