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Paul Dylan Wes, Ph.D. - Publications

Affiliations: 
Lundbeck 
Area:
Alzheimer's disease, Microglia, Neuroinflammation
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9/25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Wes PD, Easton A, Corradi J, Barten DM, Devidze N, DeCarr LB, Truong A, He A, Barrezueta NX, Polson C, Bourin C, Flynn ME, Keenan S, Lidge R, Meredith J, et al. Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease. Plos One. 9: e106050. PMID 25153994 DOI: 10.1371/Journal.Pone.0106050  0.344
2011 Cho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B, Wes P, Ransohoff RM, Gan L. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. The Journal of Biological Chemistry. 286: 32713-22. PMID 21771791 DOI: 10.1074/Jbc.M111.254268  0.346
2005 Whitworth AJ, Theodore DA, Greene JC, Benes H, Wes PD, Pallanck LJ. Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 8024-9. PMID 15911761 DOI: 10.1073/Pnas.0501078102  0.318
2005 Harrison SM, Rudolph JL, Spencer ML, Wes PD, Montell C, Andres DA, Harrison DA. Activated RIC, a small GTPase, genetically interacts with the Ras pathway and calmodulin during Drosophila development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 817-26. PMID 15712277 DOI: 10.1002/Dvdy.20346  0.559
2001 Wes PD, Bargmann CI. C. elegans odour discrimination requires asymmetric diversity in olfactory neurons. Nature. 410: 698-701. PMID 11287957 DOI: 10.1038/35070581  0.494
1999 Wes PD, Xu XZ, Li HS, Chien F, Doberstein SK, Montell C. Termination of phototransduction requires binding of the NINAC myosin III and the PDZ protein INAD. Nature Neuroscience. 2: 447-53. PMID 10321249 DOI: 10.1038/8116  0.616
1998 Xu XZ, Wes PD, Chen H, Li HS, Yu M, Morgan S, Liu Y, Montell C. Retinal targets for calmodulin include proteins implicated in synaptic transmission. The Journal of Biological Chemistry. 273: 31297-307. PMID 9813038 DOI: 10.1074/Jbc.273.47.31297  0.62
1996 Wes PD, Yu M, Montell C. RIC, a calmodulin-binding Ras-like GTPase. The Embo Journal. 15: 5839-48. PMID 8918462 DOI: 10.1002/J.1460-2075.1996.Tb00971.X  0.607
1995 Wes PD, Chevesich J, Jeromin A, Rosenberg C, Stetten G, Montell C. TRPC1, a human homolog of a Drosophila store-operated channel. Proceedings of the National Academy of Sciences of the United States of America. 92: 9652-6. PMID 7568191 DOI: 10.1073/Pnas.92.21.9652  0.524
Low-probability matches (unlikely to be authored by this person)
2015 Holtman IR, Raj DD, Miller JA, Schaafsma W, Yin Z, Brouwer N, Wes PD, Möller T, Orre M, Kamphuis W, Hol EM, Boddeke EW, Eggen BJ. Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis. Acta Neuropathologica Communications. 3: 31. PMID 26001565 DOI: 10.1186/S40478-015-0203-5  0.292
2015 Wes PD, Holtman IR, Boddeke EW, Möller T, Eggen BJ. Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease. Glia. PMID 26040959 DOI: 10.1002/Glia.22866  0.292
2017 Galatro TF, Holtman IR, Lerario AM, Vainchtein ID, Brouwer N, Sola PR, Veras MM, Pereira TF, Leite REP, Möller T, Wes PD, Sogayar MC, Laman JD, den Dunnen W, Pasqualucci CA, et al. Transcriptomic analysis of purified human cortical microglia reveals age-associated changes. Nature Neuroscience. PMID 28671693 DOI: 10.1038/Nn.4597  0.288
2015 Sankaranarayanan S, Barten DM, Vana L, Devidze N, Yang L, Cadelina G, Hoque N, DeCarr L, Keenan S, Lin A, Cao Y, Snyder B, Zhang B, Nitla M, Hirschfeld G, ... ... Wes P, et al. Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models. Plos One. 10: e0125614. PMID 25933020 DOI: 10.1371/Journal.Pone.0125614  0.285
2008 Trinh K, Moore K, Wes PD, Muchowski PJ, Dey J, Andrews L, Pallanck LJ. Induction of the phase II detoxification pathway suppresses neuron loss in Drosophila models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 465-72. PMID 18184789 DOI: 10.1523/Jneurosci.4778-07.2008  0.283
2016 Wes PD, Sayed FA, Bard F, Gan L. Targeting microglia for the treatment of Alzheimer's Disease. Glia. PMID 27100611 DOI: 10.1002/Glia.22988  0.28
2005 Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, Wes PD, Pallanck LJ, Bonini NM. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Current Biology : Cb. 15: 1572-7. PMID 16139213 DOI: 10.1016/J.Cub.2005.07.064  0.278
2011 Barten DM, Cadelina GW, Hoque N, DeCarr LB, Guss VL, Yang L, Sankaranarayanan S, Wes PD, Flynn ME, Meredith JE, Ahlijanian MK, Albright CF. Tau transgenic mice as models for cerebrospinal fluid tau biomarkers. Journal of Alzheimer's Disease : Jad. 24: 127-41. PMID 21422517 DOI: 10.3233/Jad-2011-110161  0.267
2006 Whitworth AJ, Wes PD, Pallanck LJ. Drosophila models pioneer a new approach to drug discovery for Parkinson's disease. Drug Discovery Today. 11: 119-26. PMID 16533709 DOI: 10.1016/S1359-6446(05)03693-7  0.246
2012 Hlavacova N, Wes PD, Ondrejcakova M, Flynn ME, Poundstone PK, Babic S, Murck H, Jezova D. Subchronic treatment with aldosterone induces depression-like behaviours and gene expression changes relevant to major depressive disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 247-65. PMID 21375792 DOI: 10.1017/S1461145711000368  0.237
2010 Cacace AM, Wes P, Flynn M, Kieras C, Sankaranaryanan S, Toyn J, Poundstone P, Chen L, Fennell M, Charles F. P1-105: Human neural progenitor cells as an in vitro model system to study mitochondrial dysfunction in Alzheimer's disease Alzheimer's & Dementia. 6: S205-S205. DOI: 10.1016/J.Jalz.2010.05.654  0.226
2016 Möller T, Bard F, Bhattacharya A, Biber K, Campbell B, Dale E, Eder C, Gan L, Garden GA, Hughes ZA, Pearse DD, Staal RG, Sayed FA, Wes PD, Boddeke HW. Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor. Glia. PMID 27246804 DOI: 10.1002/Glia.23007  0.2
2011 Kitazawa M, Cheng D, Tsukamoto MR, Koike MA, Wes PD, Vasilevko V, Cribbs DH, LaFerla FM. Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model. Journal of Immunology (Baltimore, Md. : 1950). 187: 6539-49. PMID 22095718 DOI: 10.4049/Jimmunol.1100620  0.167
2020 Doller D, Wes P. Quality of Research Tools. Handbook of Experimental Pharmacology. 257: 119-145. PMID 31620916 DOI: 10.1007/164_2019_281  0.097
2015 Wes PD, Holtman IR, Boddeke EWGM, Möller T, Eggen BJL. Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease Glia. DOI: 10.1002/glia.22866  0.078
2014 Möller T, Wes PD, Doller D. Microglial biology in neuroinflammatory disease: Pharmaco-industrial approach to target validation Pathological Potential of Neuroglia: Possible New Targets For Medical Intervention. 187-211. DOI: 10.1007/978-1-4939-0974-2-9  0.068
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