Ferdinando Nicoletti, Ph.D/MD - Publications

Affiliations: 
Pharmacology Sapienza University of Rome, Roma, Lazio, Italy 

222 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Matrisciano F, Locci V, Dong E, Nicoletti F, Guidotti A, Grayson DR. Altered Expression and in vivo Activity of mGlu5 variant a Receptors in the striatum of BTBR mice: Novel insights into the pathophysiology of adult idiopathic forms of autism spectrum disorders. Current Neuropharmacology. PMID 35139800 DOI: 10.2174/1567202619999220209112609  0.477
2020 Celli R, Wall MJ, Santolini I, Vergassola M, Di Menna L, Mascio G, Cannella M, van Luijtelaar G, Pittaluga A, Ciruela F, Bruno V, Nicoletti F, Ngomba RT. Pharmacological activation of mGlu5 receptors with the positive allosteric modulator, VU0360172 modulates thalamic GABAergic transmission. Neuropharmacology. 108240. PMID 32768418 DOI: 10.1016/J.Neuropharm.2020.108240  0.318
2020 Sebastianutto I, Goyet E, Andreoli L, Font-Ingles J, Moreno-Delgado D, Bouquier N, Jahannault-Talignani C, Moutin E, Di Menna L, Maslava N, Pin JP, Fagni L, Nicoletti F, Ango F, Cenci MA, et al. D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson's disease. The Journal of Clinical Investigation. PMID 32039920 DOI: 10.1172/Jci126361  0.304
2019 Petralia MC, Mazzon E, Basile MS, Cutuli M, Di Marco R, Scandurra F, Saraceno A, Fagone P, Nicoletti F, Mangano K. Effects of Treatment with the Hypomethylating Agent 5-aza-2'-deoxycytidine in Murine Type II Collagen-Induced Arthritis. Pharmaceuticals (Basel, Switzerland). 12. PMID 31783688 DOI: 10.3390/Ph12040174  0.303
2019 Imbriglio T, Verhaeghe R, Martinello K, Pascarelli MT, Chece G, Bucci D, Notartomaso S, Quattromani M, Mascio G, Scalabrì F, Simeone A, Maccari S, Del Percio C, Wieloch T, Fucile S, ... ... Nicoletti F, et al. Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901093RRR. PMID 31665922 DOI: 10.1096/Fj.201901093Rrr  0.343
2019 Cavalli E, Mazzon E, Mammana S, Basile MS, Lombardo SD, Mangano K, Bramanti P, Nicoletti F, Fagone P, Petralia MC. Overexpression of Macrophage Migration Inhibitory Factor and Its Homologue D-Dopachrome Tautomerase as Negative Prognostic Factor in Neuroblastoma. Brain Sciences. 9. PMID 31635049 DOI: 10.3390/Brainsci9100284  0.301
2019 Buonaguro EF, Morley-Fletcher S, Avagliano C, Vellucci L, Iasevoli F, Bouwalerh H, Van Camp G, Nicoletti F, Maccari S, de Bartolomeis A. Glutamatergic postsynaptic density in early life stress programming: Topographic gene expression of mGlu5 receptors and Homer proteins. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 109725. PMID 31404590 DOI: 10.1016/J.Pnpbp.2019.109725  0.301
2019 Lombardo SD, Mazzon E, Basile MS, Cavalli E, Bramanti P, Nania R, Fagone P, Nicoletti F, Petralia MC. Upregulation of IL-1 Receptor Antagonist in a Mouse Model of Migraine. Brain Sciences. 9. PMID 31331109 DOI: 10.3390/Brainsci9070172  0.334
2019 Busceti CL, Ferese R, Bucci D, Ryskalin L, Gambardella S, Madonna M, Nicoletti F, Fornai F. Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures. International Journal of Molecular Sciences. 20. PMID 31197099 DOI: 10.3390/Ijms20122901  0.317
2019 Morley-Fletcher S, Mairesse J, Van Camp G, Reynaert ML, Gatta E, Marrocco J, Bouwalerh H, Nicoletti F, Maccari S. Perinatal Stress Programs Sex Differences in the Behavioral and Molecular Chronobiological Profile of Rats Maintained Under a 12-h Light-Dark Cycle. Frontiers in Molecular Neuroscience. 12: 89. PMID 31118884 DOI: 10.3389/Fnmol.2019.00089  0.661
2019 Nicoletti F, Orlando R, Di Menna L, Cannella M, Notartomaso S, Mascio G, Iacovelli L, Matrisciano F, Fazio F, Caraci F, Copani A, Battaglia G, Bruno V. Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia. Frontiers in Psychiatry. 10: 49. PMID 30890967 DOI: 10.3389/Fpsyt.2019.00049  0.341
2019 Celli R, Santolini I, van Luijtelaar G, Ngomba RT, Bruno V, Nicoletti F. Targeting metabotropic glutamate receptors in the treatment of epilepsy: rationale and current status. Expert Opinion On Therapeutic Targets. PMID 30801204 DOI: 10.1080/14728222.2019.1586885  0.342
2018 Matrisciano F, Dong E, Nicoletti F, Guidotti A. Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors. Frontiers in Molecular Neuroscience. 11: 423. PMID 30564095 DOI: 10.3389/Fnmol.2018.00423  0.526
2018 Spampinato SF, Copani A, Nicoletti F, Sortino MA, Caraci F. Metabotropic Glutamate Receptors in Glial Cells: A New Potential Target for Neuroprotection? Frontiers in Molecular Neuroscience. 11: 414. PMID 30483053 DOI: 10.3389/Fnmol.2018.00414  0.374
2018 Günther S, Fagone P, Jalce G, Atanasov A, Guignabert C, Nicoletti F. Role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: from pathogenic factors to therapeutic targets. Drug Discovery Today. PMID 30439447 DOI: 10.1016/J.Drudis.2018.11.003  0.3
2018 Joffe ME, Santiago CI, Stansley BJ, Maksymetz J, Gogliotti RG, Engers JL, Nicoletti F, Lindsley CW, Conn PJ. Mechanisms underlying prelimbic prefrontal cortex mGlu/mGlu-dependent plasticity and reversal learning deficits following acute stress. Neuropharmacology. PMID 30326237 DOI: 10.1016/J.Neuropharm.2018.10.013  0.307
2018 Busceti CL, Di Menna L, Bianchi F, Mastroiacovo F, Di Pietro P, Traficante A, Bozza G, Niehrs C, Battaglia G, Bruno V, Fornai F, Volpe M, Rubattu S, Nicoletti F. Dickkopf-3 Causes Neuroprotection by Inducing Vascular Endothelial Growth Factor. Frontiers in Cellular Neuroscience. 12: 292. PMID 30258353 DOI: 10.3389/Fncel.2018.00292  0.318
2018 Notartomaso S, Nakao H, Mascio G, Scarselli P, Cannella M, Zappulla C, Madonna M, Motolese M, Gradini R, Liberatore F, Zonta M, Carmignoto G, Battaglia G, Bruno V, Watanabe M, ... ... Nicoletti F, et al. mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors. Scientific Reports. 8: 13361. PMID 30190524 DOI: 10.1038/S41598-018-31369-7  0.341
2018 Zuena AR, Iacovelli L, Orlando R, Di Menna L, Casolini P, Alemà GS, Di Cicco G, Battaglia G, Nicoletti F. Non-radioactive Assessment of mGlu5 Receptor-Activated Polyphosphoinositide Hydrolysis in Response to Systemic Administration of a Positive Allosteric Modulator. Frontiers in Pharmacology. 9: 804. PMID 30108503 DOI: 10.3389/Fphar.2018.00804  0.343
2018 Fagone P, Mazzon E, Chikovani T, Saraceno A, Mammana S, Colletti G, Mangano K, Bramanti P, Nicoletti F. Decitabine induces regulatory T cells, inhibits the production of IFN-gamma and IL-17 and exerts preventive and therapeutic efficacy in rodent experimental autoimmune neuritis. Journal of Neuroimmunology. 321: 41-48. PMID 29957387 DOI: 10.1016/J.Jneuroim.2018.05.013  0.303
2018 Fagone P, Mazzon E, Cavalli E, Bramanti A, Petralia MC, Mangano K, Al-Abed Y, Bramati P, Nicoletti F. Contribution of the macrophage migration inhibitory factor superfamily of cytokines in the pathogenesis of preclinical and human multiple sclerosis: In silico and in vivo evidences. Journal of Neuroimmunology. PMID 29935880 DOI: 10.1016/J.Jneuroim.2018.06.009  0.319
2018 Murat S, Bigot M, Chapron J, König GM, Kostenis E, Battaglia G, Nicoletti F, Bourinet E, Bockaert J, Marin P, Vandermoere F. 5-HT receptor-dependent phosphorylation of mGlu receptor at Serine 843 promotes mGlu receptor-operated G signaling. Molecular Psychiatry. PMID 29858599 DOI: 10.1038/S41380-018-0069-6  0.315
2018 Nicoletti F, Battaglia G, Bruno V. Editorial overview: Neurosciences: Metabotropic glutamate receptors: still promising drug targets for CNS disorders. Current Opinion in Pharmacology. 38: v-vii. PMID 29751975 DOI: 10.1016/J.Coph.2018.04.013  0.314
2018 Gatta E, Mairesse J, Deruyter L, Marrocco J, Van Camp G, Bouwalerh H, Lo Guidice JM, Morley-Fletcher S, Nicoletti F, Maccari S. Reduced maternal behavior caused by gestational stress is predictive of life span changes in risk-taking behavior and gene expression due to altering of the stress/anti-stress balance. Neurotoxicology. 66: 138-149. PMID 29630914 DOI: 10.1016/J.Neuro.2018.04.005  0.68
2018 Nardecchia F, Orlando R, Iacovelli L, Colamartino M, Fiori E, Leuzzi V, Piccinin S, Nistico R, Puglisi-Allegra S, Di Menna L, Battaglia G, Nicoletti F, Pascucci T. Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria. Frontiers in Neuroscience. 12: 154. PMID 29615849 DOI: 10.3389/Fnins.2018.00154  0.355
2018 Iacovelli L, Orlando R, Rossi A, Spinsanti P, Melchiorri D, Nicoletti F. Targeting metabotropic glutamate receptors in the treatment of primary brain tumors. Current Opinion in Pharmacology. 38: 59-64. PMID 29525720 DOI: 10.1016/J.Coph.2018.02.005  0.314
2017 Caraci F, Nicoletti F, Copani A. Metabotropic glutamate receptors: the potential for therapeutic applications in Alzheimer's disease. Current Opinion in Pharmacology. 38: 1-7. PMID 29278824 DOI: 10.1016/J.Coph.2017.12.001  0.332
2017 Beneventano M, Spampinato SF, Merlo S, Chisari M, Platania P, Ragusa M, Purrello M, Nicoletti F, Sortino MA. Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death. Frontiers in Pharmacology. 8: 812. PMID 29170640 DOI: 10.3389/Fphar.2017.00812  0.366
2017 Di Menna L, Joffe ME, Iacovelli L, Orlando R, Lindsley CW, Mairesse J, Gressèns P, Cannella M, Caraci F, Copani A, Bruno V, Battaglia G, Conn PJ, Nicoletti F. Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system. Neuropharmacology. PMID 29079293 DOI: 10.1016/J.Neuropharm.2017.10.026  0.353
2017 Liberatore F, Bucci D, Mascio G, Madonna M, Di Pietro P, Beneventano M, Maria Puliti A, Battaglia G, Bruno V, Nicoletti F, Romano MR. Permissive role for mglu1 metabotropic glutamate receptors in excitotoxic retinal degeneration. Neuroscience. PMID 28918254 DOI: 10.1016/J.Neuroscience.2017.09.005  0.352
2017 Font J, López-Cano M, Notartomaso S, Scarselli P, Di Pietro P, Bresolí-Obach R, Battaglia G, Malhaire F, Rovira X, Catena J, Giraldo J, Pin JP, Fernández-Dueñas V, Goudet C, Nonell S, ... Nicoletti F, et al. Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. Elife. 6. PMID 28395733 DOI: 10.7554/Elife.23545  0.333
2017 Weisz F, Piccinin S, Mango D, Ngomba RT, Mercuri NB, Nicoletti F, Nisticò R. The role of adiponectin receptors in the regulation of synaptic transmission in the hippocampus. Synapse (New York, N.Y.). PMID 28187508 DOI: 10.1002/Syn.21964  0.306
2016 Collingridge G, Manahan-Vaughan D, Nicoletti F, Schoepp D. Metabotropic Glutamate Receptors, 5 years on. Neuropharmacology. PMID 27908770 DOI: 10.1016/J.Neuropharm.2016.09.029  0.306
2016 Panaccione I, Iacovelli L, Nuzzo LD, Nardecchia F, Mauro G, Janiri D, Blasi A, Sani G, Nicoletti F, Orlando R. Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus. Pharmacological Research. PMID 27890550 DOI: 10.1016/J.Phrs.2016.11.029  0.309
2016 Iacovelli L, Di Menna L, Peterlik D, Stangl C, Orlando R, Molinaro G, De Blasi A, Bruno V, Battaglia G, Flor PJ, Uschold-Schmidt N, Nicoletti F. Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling. Neuropharmacology. PMID 27769854 DOI: 10.1016/J.Neuropharm.2016.10.018  0.343
2016 Nikolic I, Stojanovic I, Vujicic M, Fagone P, Mangano K, Stosic-Grujicic S, Nicoletti F, Saksida T. Standardized bovine colostrum derivative impedes development of type 1 diabetes in rodents. Immunobiology. PMID 27693017 DOI: 10.1016/J.Imbio.2016.09.013  0.302
2016 Nicoletti F. Shedding Light on Metabotropic Glutamate Receptors. Cell Chemical Biology. 23: 887-8. PMID 27541192 DOI: 10.1016/J.Chembiol.2016.08.001  0.317
2016 Notartomaso S, Mascio G, Scarselli P, Martinello K, Fucile S, Gradini R, Bruno V, Battaglia G, Nicoletti F. Expression of the K(+)/Cl(-) cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors. Neuropharmacology. PMID 27498071 DOI: 10.1016/J.Neuropharm.2016.07.032  0.371
2016 Fazio F, Lionetto L, Curto M, Iacovelli L, Copeland CS, Neale SA, Bruno V, Battaglia G, Salt TE, Nicoletti F. Cinnabarinic acid and xanthurenic acid: Two kynurenine metabolites that interact with metabotropic glutamate receptors. Neuropharmacology. PMID 27342123 DOI: 10.1016/J.Neuropharm.2016.06.020  0.32
2016 Bruno V, Caraci F, Copani A, Matrisciano F, Nicoletti F, Battaglia G. The impact of metabotropic glutamate receptors into active neurodegenerative processes: A "dark side" in the development of new symptomatic treatments for neurologic and psychiatric disorders. Neuropharmacology. PMID 27140693 DOI: 10.1016/J.Neuropharm.2016.04.044  0.319
2016 Leggio GM, Catania MV, Puzzo D, Spatuzza M, Pellitteri R, Gulisano W, Torrisi SA, Giurdanella G, Piazza C, Impellizzeri AR, Gozzo L, Navarria A, Bucolo C, Nicoletti F, Palmeri A, et al. The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ß1-42 oligomers in mice. Pharmacological Research. 106: 10-20. PMID 26875816 DOI: 10.1016/J.Phrs.2016.02.007  0.301
2016 Gatta E, Lefebvre T, Gaetani S, Santos MD, Marrocco J, Mir AM, Cassano T, Maccari S, Nicoletti F, Mairesse J. Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer's disease. Pharmacological Research. PMID 26816085 DOI: 10.1016/J.Phrs.2016.01.006  0.651
2016 Matrisciano F, Panaccione I, Grayson DR, Nicoletti F, Guidotti A. Metabotropic Glutamate 2/3 Receptors and Epigenetic Modifications in Psychotic Disorders: A Review. Current Neuropharmacology. 14: 41-7. PMID 26813121 DOI: 10.2174/1570159X13666150713174242  0.514
2016 Romano MR, Di Menna L, Scarselli P, Mascio G, Madonna M, Notartomaso S, Puliti A, Bruno V, Battaglia G, Nicoletti F. Type-1, but Not Type-5, Metabotropic Glutamate Receptors are Coupled to Polyphosphoinositide Hydrolysis in the Retina. Neurochemical Research. 41: 924-32. PMID 26700429 DOI: 10.1007/S11064-015-1775-Y  0.341
2016 Castrogiovanni P, Trovato FM, Szychlinska MA, Loreto C, Giunta S, Scuderi S, Passanisi R, Fidone F, Fagone P, Imbesi R, Nicoletti F, Castorina S. Effects of Synthetic Anti-Inflammatory Sterol in CB3V-Induced Myocarditis: A Morphological Study on Heart Muscle Tissue Journal of Functional Morphology and Kinesiology. 1: 69-89. DOI: 10.3390/Jfmk1010069  0.301
2016 Matriscianoa F, Panaccione I, Grayson DR, Nicoletti F, Guidotti A. Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: A review Current Neuropharmacology. 14: 41-47.  0.418
2015 Nicoletti F. Kynurenine pathway metabolites in migraine. The Journal of Headache and Pain. 16: A1. PMID 28132387 DOI: 10.1186/1129-2377-16-S1-A1  0.363
2015 Curto M, Lionetto L, Capi M, Negro A, D'Alonzo L, Nicoletti F, Martelletti P. O066. Kynurenine pathway metabolites in cluster headache. The Journal of Headache and Pain. 16: A87. PMID 28132301 DOI: 10.1186/1129-2377-16-S1-A87  0.315
2015 Curto M, Lionetto L, Negro A, Capi M, Fazio F, Giamberardino MA, Simmaco M, Nicoletti F, Martelletti P. Altered kynurenine pathway metabolites in serum of chronic migraine patients. The Journal of Headache and Pain. 17: 47. PMID 27130315 DOI: 10.1186/S10194-016-0638-5  0.321
2015 Fazio F, Lionetto L, Curto M, Iacovelli L, Cavallari M, Zappulla C, Ulivieri M, Napoletano F, Capi M, Corigliano V, Scaccianoce S, Caruso A, Miele J, De Fusco A, Di Menna L, ... ... Nicoletti F, et al. Xanthurenic Acid Activates mGlu2/3 Metabotropic Glutamate Receptors and is a Potential Trait Marker for Schizophrenia. Scientific Reports. 5: 17799. PMID 26643205 DOI: 10.1038/Srep17799  0.3
2015 Motolese M, Mastroiacovo F, Cannella M, Bucci D, Gaglione A, Riozzi B, Lütjens R, Poli SM, Celanire S, Bruno V, Battaglia G, Nicoletti F. Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage. Molecular Brain. 8: 66. PMID 26496940 DOI: 10.1186/S13041-015-0158-2  0.319
2015 Mairesse J, Gatta E, Reynaert ML, Marrocco J, Morley-Fletcher S, Soichot M, Deruyter L, Camp GV, Bouwalerh H, Fagioli F, Pittaluga A, Allorge D, Nicoletti F, Maccari S. Activation of presynaptic oxytocin receptors enhances glutamate release in the ventral hippocampus of prenatally restraint stressed rats. Psychoneuroendocrinology. 62: 36-46. PMID 26231445 DOI: 10.1016/J.Psyneuen.2015.07.005  0.702
2015 di Nuzzo L, Orlando R, Tognoli C, Di Pietro P, Bertini G, Miele J, Bucci D, Motolese M, Scaccianoce S, Caruso A, Mauro G, De Lucia C, Battaglia G, Bruno V, Fabene PF, ... Nicoletti F, et al. Antidepressant activity of fingolimod in mice. Pharmacology Research & Perspectives. 3: e00135. PMID 26171219 DOI: 10.1002/Prp2.135  0.306
2015 Busceti CL, Di Pietro P, Riozzi B, Traficante A, Biagioni F, Nisticò R, Fornai F, Battaglia G, Nicoletti F, Bruno V. 5-HT(2C) serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice. Pharmacological Research. 99: 258-68. PMID 26145279 DOI: 10.1016/J.Phrs.2015.06.017  0.312
2015 Truini A, Piroso S, Pasquale E, Notartomaso S, Di Stefano G, Lattanzi R, Battaglia G, Nicoletti F, Cruccu G. N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans. Molecular Pain. 11: 14. PMID 25889381 DOI: 10.1186/S12990-015-0009-2  0.346
2015 Cannella M, Motolese M, Bucci D, Molinaro G, Gradini R, Bruno V, Nicoletti F, Battaglia G. Changes in the expression of genes encoding for mGlu4 and mGlu5 receptors and other regulators of the indirect pathway in acute mouse models of drug-induced parkinsonism. Neuropharmacology. 95: 50-8. PMID 25747602 DOI: 10.1016/J.Neuropharm.2015.02.024  0.348
2015 Nicoletti F, Bruno V, Ngomba RT, Gradini R, Battaglia G. Metabotropic glutamate receptors as drug targets: what's new? Current Opinion in Pharmacology. 20: 89-94. PMID 25506748 DOI: 10.1016/J.Coph.2014.12.002  0.313
2015 Battaglia G, Riozzi B, Bucci D, Di Menna L, Molinaro G, Pallottino S, Nicoletti F, Bruno V. Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis. Neurobiology of Disease. 74: 126-36. PMID 25434487 DOI: 10.1016/J.Nbd.2014.11.012  0.307
2015 Reynaert ML, Marrocco J, Gatta E, Mairesse J, Van Camp G, Fagioli F, Maccari S, Nicoletti F, Morley-Fletcher S. A self-medication hypothesis for increased vulnerability to drug abuse in prenatally restraint stressed rats. Advances in Neurobiology. 10: 101-20. PMID 25287538 DOI: 10.1007/978-1-4939-1372-5_6  0.679
2015 Mairesse J, Van Camp G, Gatta E, Marrocco J, Reynaert ML, Consolazione M, Morley-Fletcher S, Nicoletti F, Maccari S. Sleep in prenatally restraint stressed rats, a model of mixed anxiety-depressive disorder. Advances in Neurobiology. 10: 27-44. PMID 25287534 DOI: 10.1007/978-1-4939-1372-5_2  0.667
2015 Nasca C, Bigio B, Zelli D, Nicoletti F, McEwen BS. Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility. Molecular Psychiatry. 20: 755-63. PMID 25178162 DOI: 10.1038/Mp.2014.96  0.32
2014 Spampinato SF, Merlo S, Chisari M, Nicoletti F, Sortino MA. Glial metabotropic glutamate receptor-4 increases maturation and survival of oligodendrocytes. Frontiers in Cellular Neuroscience. 8: 462. PMID 25642169 DOI: 10.3389/Fncel.2014.00462  0.359
2014 Orlando R, Borro M, Motolese M, Molinaro G, Scaccianoce S, Caruso A, di Nuzzo L, Caraci F, Matrisciano F, Pittaluga A, Mairesse J, Simmaco M, Nisticò R, Monn JA, Nicoletti F. Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740. Neuropharmacology. 86: 133-44. PMID 25063582 DOI: 10.1016/J.Neuropharm.2014.07.009  0.35
2014 di Nuzzo L, Orlando R, Nasca C, Nicoletti F. Molecular pharmacodynamics of new oral drugs used in the treatment of multiple sclerosis. Drug Design, Development and Therapy. 8: 555-68. PMID 24876766 DOI: 10.2147/Dddt.S52428  0.322
2014 Mangano K, Fagone P, Bendtzen K, Meroni PL, Quattrocchi C, Mammana S, Di Rosa M, Malaguarnera L, Coco M, Magro G, Di Marco R, Nicoletti F. Hypomethylating agent 5-aza-2'-deoxycytidine (DAC) ameliorates multiple sclerosis in mouse models. Journal of Cellular Physiology. 229: 1918-25. PMID 24700487 DOI: 10.1002/Jcp.24641  0.317
2014 Pignatelli M, Piccinin S, Molinaro G, Di Menna L, Riozzi B, Cannella M, Motolese M, Vetere G, Catania MV, Battaglia G, Nicoletti F, Nisticò R, Bruno V. Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4558-66. PMID 24672001 DOI: 10.1523/Jneurosci.1846-13.2014  0.352
2014 Mango D, Barbato G, Piccirilli S, Panico MB, Feligioni M, Schepisi C, Graziani M, Porrini V, Benarese M, Lanzillotta A, Pizzi M, Pieraccini S, Sironi M, Blandini F, Nicoletti F, et al. Electrophysiological and metabolic effects of CHF5074 in the hippocampus: protection against in vitro ischemia. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 81: 83-90. PMID 24630950 DOI: 10.1016/J.Phrs.2014.02.010  0.344
2014 D'Antoni S, Spatuzza M, Bonaccorso CM, Musumeci SA, Ciranna L, Nicoletti F, Huber KM, Catania MV. Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism. Neuroscience and Biobehavioral Reviews. 46: 228-41. PMID 24548786 DOI: 10.1016/J.Neubiorev.2014.02.003  0.34
2014 Fagone P, Muthumani K, Mangano K, Magro G, Meroni PL, Kim JJ, Sardesai NY, Weiner DB, Nicoletti F. VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus. Immunology. 142: 594-602. PMID 24527796 DOI: 10.1111/Imm.12267  0.307
2014 Marrocco J, Reynaert ML, Gatta E, Gabriel C, Mocaër E, Di Prisco S, Merega E, Pittaluga A, Nicoletti F, Maccari S, Morley-Fletcher S, Mairesse J. The effects of antidepressant treatment in prenatally stressed rats support the glutamatergic hypothesis of stress-related disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2015-24. PMID 24501344 DOI: 10.1523/Jneurosci.4131-13.2014  0.683
2013 Notartomaso S, Zappulla C, Biagioni F, Cannella M, Bucci D, Mascio G, Scarselli P, Fazio F, Weisz F, Lionetto L, Simmaco M, Gradini R, Battaglia G, Signore M, Puliti A, ... Nicoletti F, et al. Pharmacological enhancement of mGlu1 metabotropic glutamate receptors causes a prolonged symptomatic benefit in a mouse model of spinocerebellar ataxia type 1. Molecular Brain. 6: 48. PMID 24252411 DOI: 10.1186/1756-6606-6-48  0.35
2013 Petković F, Blaževski J, Momčilović M, Timotijević G, Zocca MB, Mijatović S, Maksimović-Ivanić D, Mangano K, Fagone P, Stošić-Grujičić S, Nicoletti F, Miljković D. Saquinavir-NO inhibits S6 kinase activity, impairs secretion of the encephalytogenic cytokines interleukin-17 and interferon-gamma and ameliorates experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 259: 55-65. PMID 23602714 DOI: 10.1016/J.Jneuroim.2013.03.010  0.319
2013 Degos V, Peineau S, Nijboer C, Kaindl AM, Sigaut S, Favrais G, Plaisant F, Teissier N, Gouadon E, Lombet A, Saliba E, Collingridge GL, Maze M, Nicoletti F, Heijnen C, et al. G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration. Annals of Neurology. 73: 667-78. PMID 23494575 DOI: 10.1002/Ana.23868  0.346
2013 Nasca C, Xenos D, Barone Y, Caruso A, Scaccianoce S, Matrisciano F, Battaglia G, Mathé AA, Pittaluga A, Lionetto L, Simmaco M, Nicoletti F. L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. Proceedings of the National Academy of Sciences of the United States of America. 110: 4804-9. PMID 23382250 DOI: 10.1073/Pnas.1216100110  0.363
2013 Nisticò R, Mango D, Mandolesi G, Piccinin S, Berretta N, Pignatelli M, Feligioni M, Musella A, Gentile A, Mori F, Bernardi G, Nicoletti F, Mercuri NB, Centonze D. Inflammation subverts hippocampal synaptic plasticity in experimental multiple sclerosis. Plos One. 8: e54666. PMID 23355887 DOI: 10.1371/Journal.Pone.0054666  0.301
2013 Di Menna L, Molinaro G, Di Nuzzo L, Riozzi B, Zappulla C, Pozzilli C, Turrini R, Caraci F, Copani A, Battaglia G, Nicoletti F, Bruno V. Fingolimod protects cultured cortical neurons against excitotoxic death. Pharmacological Research. 67: 1-9. PMID 23073075 DOI: 10.1016/J.Phrs.2012.10.004  0.322
2013 Pignatelli M, Vollmayr B, Richter SH, Middei S, Matrisciano F, Molinaro G, Nasca C, Battaglia G, Ammassari-Teule M, Feligioni M, Nisticò R, Nicoletti F, Gass P. Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats. Neuropharmacology. 66: 339-47. PMID 22709946 DOI: 10.1016/J.Neuropharm.2012.05.046  0.328
2013 Iacovelli L, Nicoletti F, De Blasi A. Molecular mechanisms that desensitize metabotropic glutamate receptor signaling: an overview. Neuropharmacology. 66: 24-30. PMID 22659473 DOI: 10.1016/J.Neuropharm.2012.05.005  0.309
2013 Matrisciano F, Tueting P, Dalal I, Kadriu B, Grayson DR, Davis JM, Nicoletti F, Guidotti A. Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice. Neuropharmacology. 68: 184-94. PMID 22564440 DOI: 10.1016/J.Neuropharm.2012.04.013  0.496
2012 Marrocco J, Mairesse J, Ngomba RT, Silletti V, Van Camp G, Bouwalerh H, Summa M, Pittaluga A, Nicoletti F, Maccari S, Morley-Fletcher S. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17143-54. PMID 23197707 DOI: 10.1523/Jneurosci.1040-12.2012  0.324
2012 Bernabucci M, Notartomaso S, Zappulla C, Fazio F, Cannella M, Motolese M, Battaglia G, Bruno V, Gradini R, Nicoletti F. N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors. Molecular Pain. 8: 77. PMID 23088864 DOI: 10.1186/1744-8069-8-77  0.329
2012 Spampinato SF, Merlo S, Molinaro G, Battaglia G, Bruno V, Nicoletti F, Sortino MA. Dual effect of 17β-estradiol on NMDA-induced neuronal death: involvement of metabotropic glutamate receptor 1. Endocrinology. 153: 5940-8. PMID 23077075 DOI: 10.1210/En.2012-1799  0.343
2012 Busceti CL, Bucci D, Molinaro G, Di Pietro P, Zangrandi L, Gradini R, Moratalla R, Battaglia G, Bruno V, Nicoletti F, Fornai F. Lack or inhibition of dopaminergic stimulation induces a development increase of striatal tyrosine hydroxylase-positive interneurons. Plos One. 7: e44025. PMID 23028485 DOI: 10.1371/Journal.Pone.0044025  0.315
2012 Mojic M, Mijatovic S, Maksimovic-Ivanic D, Miljkovic D, Stosic-Grujicic S, Stankovic M, Mangano K, Travali S, Donia M, Fagone P, Zocca MB, Al-Abed Y, McCubrey JA, Nicoletti F. Therapeutic potential of nitric oxide-modified drugs in colon cancer cells. Molecular Pharmacology. 82: 700-10. PMID 22798453 DOI: 10.1124/Mol.112.077842  0.306
2012 Stojanovic I, Saksida T, Nikolic I, Nicoletti F, Stosic-Grujicic S. Macrophage migration inhibitory factor deficiency protects pancreatic islets from cytokine-induced apoptosis in vitro. Clinical and Experimental Immunology. 169: 156-63. PMID 22774990 DOI: 10.1111/J.1365-2249.2012.04607.X  0.305
2012 Pannese R, Minichino A, Pignatelli M, Delle Chiaie R, Biondi M, Nicoletti F. [Evidence on the key role of the metabotrobic glutamatergic receptors in the pathogenesis of schizophrenia: a "breakthrough" in pharmacological treatment]. Rivista Di Psichiatria. 47: 149-69. PMID 22622251 DOI: 10.1708/1069.11719  0.32
2012 Laloux C, Mairesse J, Van Camp G, Giovine A, Branchi I, Bouret S, Morley-Fletcher S, Bergonzelli G, Malagodi M, Gradini R, Nicoletti F, Darnaudéry M, Maccari S. Anxiety-like behaviour and associated neurochemical and endocrinological alterations in male pups exposed to prenatal stress. Psychoneuroendocrinology. 37: 1646-58. PMID 22444623 DOI: 10.1016/J.Psyneuen.2012.02.010  0.327
2012 Maksimovic-Ivanic D, Stosic-Grujicic S, Nicoletti F, Mijatovic S. Resistance to TRAIL and how to surmount it. Immunologic Research. 52: 157-68. PMID 22407575 DOI: 10.1007/S12026-012-8284-8  0.307
2012 Fazio F, Lionetto L, Molinaro G, Bertrand HO, Acher F, Ngomba RT, Notartomaso S, Curini M, Rosati O, Scarselli P, Di Marco R, Battaglia G, Bruno V, Simmaco M, Pin JP, ... Nicoletti F, et al. Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors. Molecular Pharmacology. 81: 643-56. PMID 22311707 DOI: 10.1124/Mol.111.074765  0.356
2012 Caraci F, Battaglia G, Sortino MA, Spampinato S, Molinaro G, Copani A, Nicoletti F, Bruno V. Metabotropic glutamate receptors in neurodegeneration/neuroprotection: still a hot topic? Neurochemistry International. 61: 559-565. PMID 22306345 DOI: 10.1016/J.Neuint.2012.01.017  0.372
2012 Matrisciano F, Tueting P, Maccari S, Nicoletti F, Guidotti A. Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 929-38. PMID 22089319 DOI: 10.1038/Npp.2011.274  0.53
2012 Chiechio S, Nicoletti F. Metabotropic glutamate receptors and the control of chronic pain. Current Opinion in Pharmacology. 12: 28-34. PMID 22040745 DOI: 10.1016/J.Coph.2011.10.010  0.327
2012 Spampinato SF, Molinaro G, Merlo S, Iacovelli L, Caraci F, Battaglia G, Nicoletti F, Bruno V, Sortino MA. Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against β-amyloid toxicity. Molecular Pharmacology. 81: 12-20. PMID 21984253 DOI: 10.1124/Mol.111.074021  0.361
2012 Spampinato SF, Merlo S, Nicoletti F, Sortino MA. A main role for metabotropic glutamate receptor 1 in the neuroprotective effect of estrogen Molecular and Cellular Pharmacology. 4: 61-67. DOI: 10.4255/Mcpharmacol.12.06  0.356
2011 Spampinato S, Trabucco A, Biasiotta A, Biagioni F, Cruccu G, Copani A, Colledge WH, Sortino MA, Nicoletti F, Chiechio S. Hyperalgesic activity of kisspeptin in mice. Molecular Pain. 7: 90. PMID 22112588 DOI: 10.1186/1744-8069-7-90  0.31
2011 Ahlem CN, Auci DL, Nicoletti F, Pieters R, Kennedy MR, Page TM, Reading CL, Enioutina EY, Frincke JM. Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome. The Journal of Steroid Biochemistry and Molecular Biology. 126: 87-94. PMID 21570467 DOI: 10.1016/J.Jsbmb.2011.04.010  0.319
2011 Ngomba RT, Santolini I, Salt TE, Ferraguti F, Battaglia G, Nicoletti F, van Luijtelaar G. Metabotropic glutamate receptors in the thalamocortical network: strategic targets for the treatment of absence epilepsy. Epilepsia. 52: 1211-22. PMID 21569017 DOI: 10.1111/J.1528-1167.2011.03082.X  0.334
2011 Matrisciano F, Dong E, Gavin DP, Nicoletti F, Guidotti A. Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain. Molecular Pharmacology. 80: 174-82. PMID 21505039 DOI: 10.1124/Mol.110.070896  0.53
2011 Matrisciano F, Busceti CL, Bucci D, Orlando R, Caruso A, Molinaro G, Cappuccio I, Riozzi B, Gradini R, Motolese M, Caraci F, Copani A, Scaccianoce S, Melchiorri D, Bruno V, ... ... Nicoletti F, et al. Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced hippocampal damage. Plos One. 6: e16447. PMID 21304589 DOI: 10.1371/Journal.Pone.0016447  0.329
2011 Caraci F, Pistarà V, Corsaro A, Tomasello F, Giuffrida ML, Sortino MA, Nicoletti F, Copani A. Neurotoxic properties of the anabolic androgenic steroids nandrolone and methandrostenolone in primary neuronal cultures. Journal of Neuroscience Research. 89: 592-600. PMID 21290409 DOI: 10.1002/Jnr.22578  0.305
2011 Zammataro M, Chiechio S, Montana MC, Traficante A, Copani A, Nicoletti F, Gereau RW. mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists. Molecular Pain. 7: 6. PMID 21235748 DOI: 10.1186/1744-8069-7-6  0.339
2011 D'Antoni S, Berretta A, Seminara G, Longone P, Giuffrida-Stella AM, Battaglia G, Sortino MA, Nicoletti F, Catania MV. A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death. Neurobiology of Disease. 42: 252-264. PMID 21232601 DOI: 10.1016/J.Nbd.2011.01.013  0.339
2011 Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, ... ... Nicoletti F, et al. Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective. Molecular Pharmacology. 79: 618-26. PMID 21159998 DOI: 10.1124/Mol.110.067488  0.362
2011 Nicoletti F, Bockaert J, Collingridge GL, Conn PJ, Ferraguti F, Schoepp DD, Wroblewski JT, Pin JP. Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology. 60: 1017-41. PMID 21036182 DOI: 10.1016/J.Neuropharm.2010.10.022  0.344
2010 Moyanova SG, Mastroiacovo F, Kortenska LV, Mitreva RG, Fardone E, Santolini I, Sobrado M, Battaglia G, Bruno V, Nicoletti F, Ngomba RT. Protective role for type 4 metabotropic glutamate receptors against ischemic brain damage. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1107-18. PMID 21157475 DOI: 10.1038/Jcbfm.2010.201  0.353
2010 Donia M, Mangano K, Quattrocchi C, Fagone P, Signorelli S, Magro G, Sfacteria A, Bendtzen K, Nicoletti F. Specific and strain-independent effects of dexamethasone in the prevention and treatment of experimental autoimmune encephalomyelitis in rodents. Scandinavian Journal of Immunology. 72: 396-407. PMID 21039734 DOI: 10.1111/J.1365-3083.2010.02451.X  0.301
2010 Fallarino F, Volpi C, Fazio F, Notartomaso S, Vacca C, Busceti C, Bicciato S, Battaglia G, Bruno V, Puccetti P, Fioretti MC, Nicoletti F, Grohmann U, Di Marco R. Metabotropic glutamate receptor-4 modulates adaptive immunity and restrains neuroinflammation. Nature Medicine. 16: 897-902. PMID 20657581 DOI: 10.1038/Nm.2183  0.341
2010 Molinaro G, Pietracupa S, Menna LD, Pescatori L, Usiello A, Battaglia G, Nicoletti F, Bruno V. D-aspartate activates mGlu receptors coupled to polyphosphoinositide hydrolysis in neonate rat brain slices. Neuroscience Letters. 478: 128-130. PMID 20452401 DOI: 10.1016/J.Neulet.2010.04.077  0.312
2010 Abrams SL, Steelman LS, Shelton JG, Chappell W, Bäsecke J, Stivala F, Donia M, Nicoletti F, Libra M, Martelli AM, McCubrey JA. Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy. Cell Cycle (Georgetown, Tex.). 9: 1839-46. PMID 20436269 DOI: 10.4161/Cc.9.9.11544  0.302
2010 Steelman LS, Abrams SL, Shelton JG, Chappell WH, Bäsecke J, Stivala F, Donia M, Nicoletti F, Libra M, Martelli AM, McCubrey JA. Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs. Cell Cycle (Georgetown, Tex.). 9: 1629-38. PMID 20372086 DOI: 10.4161/Cc.9.8.11487  0.303
2010 Piccinin S, Cinque C, Calò L, Molinaro G, Battaglia G, Maggi L, Nicoletti F, Melchiorri D, Eusebi F, Massey PV, Bashir ZI. Interaction between Ephrins and mGlu5 metabotropic glutamate receptors in the induction of long-term synaptic depression in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2835-43. PMID 20181581 DOI: 10.1523/Jneurosci.4834-09.2010  0.338
2010 Matrisciano F, Modafferi AME, Togna GI, Barone Y, Pinna G, Nicoletti F, Scaccianoce S. Repeated anabolic androgenic steroid treatment causes antidepressant-reversible alterations of the hypothalamic-pituitary-adrenal axis, BDNF levels and behavior. Neuropharmacology. 58: 1078-1084. PMID 20138062 DOI: 10.1016/J.Neuropharm.2010.01.015  0.311
2010 Mijatovic S, Maksimovic-Ivanic D, Timotijevic G, Miljkovic D, Donia M, Libra M, Coco M, McCubrey J, Al-Abed Y, Korac A, Stosic-Grujicic S, Nicoletti F. Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO. Free Radical Biology & Medicine. 48: 1090-9. PMID 20114073 DOI: 10.1016/J.Freeradbiomed.2010.01.026  0.306
2010 Chiechio S, Copani A, Zammataro M, Battaglia G, Gereau RW, Nicoletti F. Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain. Trends in Pharmacological Sciences. 31: 153-60. PMID 20064669 DOI: 10.1016/J.Tips.2009.12.003  0.332
2010 Mangano K, Nicoletti A, Patti F, Donia M, Malaguarnera L, Signorelli S, Magro G, Muzio V, Greco B, Zaratin P, Meroni P, Zappia M, Nicoletti F. Variable effects of cyclophosphamide in rodent models of experimental allergic encephalomyelitis. Clinical and Experimental Immunology. 159: 159-68. PMID 19922500 DOI: 10.1111/J.1365-2249.2009.04050.X  0.313
2010 Squitieri F, Battaglia G, Cannella M, Riozzi B, Orobello S, Maat-Schieman ML, Aronica E, Busceti CL, Ciarmiello A, Alberti S, Sassone J, Sipione S, Bruno V, Frati L, Nicoletti F. A19 Early defect of transforming growth factor β1 formation in Huntington's disease Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.222570.19  0.331
2009 Battaglia G, Molinaro G, Riozzi B, Storto M, Busceti CL, Spinsanti P, Bucci D, Liberto VD, Mudò G, Corti C, Corsi M, Nicoletti F, Belluardo N, Bruno V. Activation of mGlu3 Receptors Stimulates the Production of GDNF in Striatal Neurons Plos One. 4. PMID 19672295 DOI: 10.1371/Journal.Pone.0006591  0.389
2009 Donia M, Mijatovic S, Maksimovic-Ivanic D, Miljkovic D, Mangano K, Tumino S, Biondi A, Basile F, Al-Abed Y, Stosic-Grujicic S, Nicoletti F. The novel NO-donating compound GIT-27NO inhibits in vivo growth of human prostate cancer cells and prevents murine immunoinflammatory hepatitis. European Journal of Pharmacology. 615: 228-233. PMID 19446546 DOI: 10.1016/J.Ejphar.2009.04.069  0.302
2009 Maksimovic-Ivanic D, Mijatovic S, Miljkovic D, Harhaji-Trajkovic L, Timotijevic G, Mojic M, Dabideen D, Cheng KF, McCubrey JA, Mangano K, Al-Abed Y, Libra M, Garotta G, Stosic-Grujicic S, Nicoletti F. The antitumor properties of a nontoxic, nitric oxide-modified version of saquinavir are independent of Akt. Molecular Cancer Therapeutics. 8: 1169-78. PMID 19417156 DOI: 10.1158/1535-7163.Mct-08-0998  0.317
2009 Chiechio S, Zammataro M, Morales ME, Busceti CL, Drago F, Gereau RW, Copani A, Nicoletti F. Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain. Molecular Pharmacology. 75: 1014-20. PMID 19255242 DOI: 10.1124/Mol.108.054346  0.339
2009 Molinaro G, Battaglia G, Riozzi B, Di Menna L, Rampello L, Bruno V, Nicoletti F. Memantine treatment reduces the expression of the K(+)/Cl(-) cotransporter KCC2 in the hippocampus and cerebral cortex, and attenuates behavioural responses mediated by GABA(A) receptor activation in mice. Brain Research. 1265: 75-9. PMID 19236854 DOI: 10.1016/J.Brainres.2009.02.016  0.341
2009 Mastroiacovo F, Busceti CL, Biagioni F, Moyanova SG, Meisler MH, Battaglia G, Caricasole A, Bruno V, Nicoletti F. Induction of the Wnt antagonist, Dickkopf-1, contributes to the development of neuronal death in models of brain focal ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 264-76. PMID 18827832 DOI: 10.1038/Jcbfm.2008.111  0.304
2009 Chiechio S, Zammataro M, Gereau IV RW, Copani A, Nicoletti F. Targeting chronic pain with epigenetic drugs: Focus on mGlu2 receptors Molecular and Cellular Pharmacology. 1: 194-199. DOI: 10.4255/Mcpharmacol.09.23  0.335
2008 Ferraguti F, Crepaldi L, Nicoletti F. Metabotropic glutamate 1 receptor: Current concepts and perspectives Pharmacological Reviews. 60: 536-581. PMID 19112153 DOI: 10.1124/Pr.108.000166  0.344
2008 Nicoletti F, Collingridge G, Schoepp D. 2008 Eruptions in metabotropic glutamate receptors Neuropharmacology. 55: 391. PMID 18638495 DOI: 10.1016/J.Neuropharm.2008.07.003  0.318
2008 Fazio F, Notartomaso S, Aronica E, Storto M, Battaglia G, Vieira E, Gatti S, Bruno V, Biagioni F, Gradini R, Nicoletti F, Marco RD. Switch in the expression of mGlu1 and mGlu5 metabotropic glutamate receptors in the cerebellum of mice developing experimental autoimmune encephalomyelitis and in autoptic cerebellar samples from patients with multiple sclerosis. Neuropharmacology. 55: 491-499. PMID 18619983 DOI: 10.1016/J.Neuropharm.2008.06.066  0.351
2008 Castiglione M, Calafiore M, Costa L, Sortino MA, Nicoletti F, Copani A. Group I metabotropic glutamate receptors control proliferation, survival and differentiation of cultured neural progenitor cells isolated from the subventricular zone of adult mice. Neuropharmacology. 55: 560-567. PMID 18603270 DOI: 10.1016/J.Neuropharm.2008.05.021  0.352
2008 Modafferi AM, Diana M, Nicoletti F, Scaccianoce S. Morphine withdrawal increases metabotropic glutamate 2/3 receptors expression in nucleus accumbens. Neuroreport. 19: 911-4. PMID 18520992 DOI: 10.1097/Wnr.0B013E3283021Cc0  0.32
2008 Zuena AR, Mairesse J, Casolini P, Cinque C, Alemà GS, Morley-Fletcher S, Chiodi V, Spagnoli LG, Gradini R, Catalani A, Nicoletti F, Maccari S. Prenatal restraint stress generates two distinct behavioral and neurochemical profiles in male and female rats. Plos One. 3: e2170. PMID 18478112 DOI: 10.1371/Journal.Pone.0002170  0.314
2008 D'Antoni S, Berretta A, Bonaccorso CM, Bruno V, Aronica E, Nicoletti F, Catania MV. Metabotropic glutamate receptors in glial cells. Neurochemical Research. 33: 2436-43. PMID 18438710 DOI: 10.1007/S11064-008-9694-9  0.345
2008 Caraci F, Busceti C, Biagioni F, Aronica E, Mastroiacovo F, Cappuccio I, Battaglia G, Bruno V, Caricasole A, Copani A, Nicoletti F. The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders. Neurochemical Research. 33: 2401-6. PMID 18427981 DOI: 10.1007/S11064-008-9710-0  0.321
2008 Mangano K, Sardesai N, D'Alcamo M, Libra M, Malaguarnera L, Donia M, Bendtzen K, Meroni P, Nicoletti F. In vitro inhibition of enterobacteria-reactive CD4+CD25- T cells and suppression of immunoinflammatory colitis in mice by the novel immunomodulatory agent VGX-1027. European Journal of Pharmacology. 586: 313-21. PMID 18374912 DOI: 10.1016/J.Ejphar.2008.02.017  0.302
2008 Maksimovic-Ivanic D, Mijatovic S, Harhaji L, Miljkovic D, Dabideen D, Fan Cheng K, Mangano K, Malaponte G, Al-Abed Y, Libra M, Garotta G, Nicoletti F, Stosic-Grujicic S. Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo. Molecular Cancer Therapeutics. 7: 510-20. PMID 18347138 DOI: 10.1158/1535-7163.Mct-07-2037  0.322
2008 Stosic-Grujicic S, Stojanovic I, Maksimovic-Ivanic D, Momcilovic M, Popadic D, Harhaji L, Miljkovic D, Metz C, Mangano K, Papaccio G, Al-Abed Y, Nicoletti F. Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus. Journal of Cellular Physiology. 215: 665-75. PMID 18064633 DOI: 10.1002/Jcp.21346  0.304
2008 Molinaro G, Battaglia G, Riozzi B, Storto M, Fucile S, Eusebi F, Nicoletti F, Bruno V. GABAergic drugs become neurotoxic in cortical neurons pre-exposed to brain-derived neurotrophic factor. Molecular and Cellular Neuroscience. 37: 312-322. PMID 18055218 DOI: 10.1016/J.Mcn.2007.10.009  0.318
2008 Stojanovic I, Maksimovic-Ivanic D, Al-Abed Y, Nicoletti F, Stosic-Grujicic S. Control of the of the final stage of immune-mediated diabetes by ISO-1, an antagonist of macrophage migration inhibitory factor Archives of Biological Sciences. 60: 389-401. DOI: 10.2298/Abs0803389S  0.323
2007 Catania MV, D'Antoni S, Bonaccorso CM, Aronica E, Bear MF, Nicoletti F. Group I metabotropic glutamate receptors: a role in neurodevelopmental disorders? Molecular Neurobiology. 35: 298-307. PMID 17917118 DOI: 10.1007/S12035-007-0022-1  0.345
2007 Melchiorri D, Cappuccio I, Ciceroni C, Spinsanti P, Mosillo P, Sarichelou I, Sale P, Nicoletti F. Metabotropic glutamate receptors in stem/progenitor cells. Neuropharmacology. 53: 473-80. PMID 17675103 DOI: 10.1016/J.Neuropharm.2007.05.031  0.3
2007 Corti C, Battaglia G, Molinaro G, Riozzi B, Pittaluga A, Corsi M, Mugnaini M, Nicoletti F, Bruno V. The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8297-308. PMID 17670976 DOI: 10.1523/Jneurosci.1889-07.2007  0.365
2007 Orlando R, Caruso A, Molinaro G, Motolese M, Matrisciano F, Togna G, Melchiorri D, Nicoletti F, Bruno V. Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures. Brain Research. 1165: 21-9. PMID 17662261 DOI: 10.1016/J.Brainres.2007.06.047  0.308
2007 Nicoletti F, Battaglia G, Storto M, Ngomba RT, Iacovelli L, Arcella A, Gradini R, Sale P, Rampello L, De Vita T, Di Marco R, Melchiorri D, Bruno V. Metabotropic glutamate receptors: beyond the regulation of synaptic transmission. Psychoneuroendocrinology. 32: S40-5. PMID 17651904 DOI: 10.1016/J.Psyneuen.2007.04.015  0.349
2007 Stojanovic I, Cuzzocrea S, Mangano K, Mazzon E, Miljkovic D, Wang M, Donia M, Abed YA, Kim J, Nicoletti F, Stosic-Grujicic S, Claesson M. In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models. Clinical Immunology. 123: 311-323. PMID 17449326 DOI: 10.1016/J.Clim.2007.03.004  0.31
2007 Nicoletti F, Arcella A, Iacovelli L, Battaglia G, Giangaspero F, Melchiorri D. Metabotropic glutamate receptors: new targets for the control of tumor growth? Trends in Pharmacological Sciences. 28: 206-13. PMID 17433452 DOI: 10.1016/J.Tips.2007.03.008  0.324
2007 Ciccarelli R, D'Alimonte I, Ballerini P, D'Auro M, Nargi E, Buccella S, Iorio PD, Bruno V, Nicoletti F, Caciagli F. Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes. Molecular Pharmacology. 71: 1369-1380. PMID 17293559 DOI: 10.1124/Mol.106.031617  0.341
2007 Beraudi A, Bruno V, Battaglia G, Biagioni F, Rampello L, Nicoletti F, Poli A. Pharmacological activation of mGlu2/3 metabotropic glutamate receptors protects retinal neurons against anoxic damage in the goldfish Carassius auratus. Experimental Eye Research. 84: 544-52. PMID 17196590 DOI: 10.1016/J.Exer.2006.11.008  0.334
2006 Spinsanti P, De Vita T, Di Castro S, Storto M, Formisano P, Nicoletti F, Melchiorri D. Endogenously activated mGlu5 metabotropic glutamate receptors sustain the increase in c-Myc expression induced by leukaemia inhibitory factor in cultured mouse embryonic stem cells. Journal of Neurochemistry. 99: 299-307. PMID 16987252 DOI: 10.1111/J.1471-4159.2006.04038.X  0.317
2006 Iacovelli L, Arcella A, Battaglia G, Pazzaglia S, Aronica E, Spinsanti P, Caruso A, De Smaele E, Saran A, Gulino A, D'Onofrio M, Giangaspero F, Nicoletti F. Pharmacological activation of mGlu4 metabotropic glutamate receptors inhibits the growth of medulloblastomas. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8388-97. PMID 16899734 DOI: 10.1523/Jneurosci.2285-06.2006  0.378
2006 Battaglia G, Busceti CL, Molinaro G, Biagioni F, Traficante A, Nicoletti F, Bruno V. Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7222-9. PMID 16822979 DOI: 10.1523/Jneurosci.1595-06.2006  0.338
2006 Cappuccio I, Verani R, Spinsanti P, Niccolini C, Gradini R, Costantino S, Nicoletti F, Melchiorri D. Context-dependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors Neuropharmacology. 51: 606-611. PMID 16806298 DOI: 10.1016/J.Neuropharm.2006.05.007  0.347
2006 Calò L, Cinque C, Patanè M, Schillaci D, Battaglia G, Melchiorri D, Nicoletti F, Bruno V. Interaction between ephrins/Eph receptors and excitatory amino acid receptors: possible relevance in the regulation of synaptic plasticity and in the pathophysiology of neuronal degeneration. Journal of Neurochemistry. 98: 1-10. PMID 16805791 DOI: 10.1111/J.1471-4159.2006.03844.X  0.344
2006 Chiechio S, Copani A, De Petris L, Morales ME, Nicoletti F, Gereau RW. Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine. Molecular Pain. 2: 20. PMID 16764720 DOI: 10.1186/1744-8069-2-20  0.309
2006 Iacovelli L, Fulceri F, De Blasi A, Nicoletti F, Ruggieri S, Fornai F. The neurotoxicity of amphetamines: bridging drugs of abuse and neurodegenerative disorders. Experimental Neurology. 201: 24-31. PMID 16678160 DOI: 10.1016/J.Expneurol.2006.02.130  0.309
2006 Storto M, Capobianco L, Battaglia G, Molinaro G, Gradini R, Riozzi B, Di Mambro A, Mitchell KJ, Bruno V, Vairetti MP, Rutter GA, Nicoletti F. Insulin secretion is controlled by mGlu5 metabotropic glutamate receptors. Molecular Pharmacology. 69: 1234-41. PMID 16424079 DOI: 10.1124/Mol.105.018390  0.32
2005 Conn PJ, Battaglia G, Marino MJ, Nicoletti F. Metabotropic glutamate receptors in the basal ganglia motor circuit Nature Reviews Neuroscience. 6: 787-798. PMID 16276355 DOI: 10.1038/Nrn1763  0.317
2005 Arcella A, Carpinelli G, Battaglia G, D'Onofrio M, Santoro F, Ngomba RT, Bruno V, Casolini P, Giangaspero F, Nicoletti F. Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo. Neuro-Oncology. 7: 236-45. PMID 16053698 DOI: 10.1215/S1152851704000961  0.356
2005 Cappuccio I, Spinsanti P, Porcellini A, Desiderati F, Vita TD, Storto M, Capobianco L, Battaglia G, Nicoletti F, Melchiorri D. Endogenous activation of mGlu5 metabotropic glutamate receptors supports self-renewal of cultured mouse embryonic stem cells. Neuropharmacology. 49: 196-205. PMID 16023153 DOI: 10.1016/J.Neuropharm.2005.05.014  0.345
2005 Kramer D, Caruso A, Nicoletti F, Genazzani AA. Somatostatin and the somatostatin receptor 2 are reciprocally controlled by calcineurin during cerebellar granule cell maturation Journal of Neurochemistry. 94: 1374-1383. PMID 16000155 DOI: 10.1111/J.1471-4159.2005.03285.X  0.318
2005 Matrisciano F, Scaccianoce S, Del Bianco P, Panaccione I, Canudas AM, Battaglia G, Riozzi B, Ngomba RT, Molinaro G, Tatarelli R, Melchiorri D, Nicoletti F. Metabotropic glutamate receptors and neuroadaptation to antidepressants: imipramine-induced down-regulation of beta-adrenergic receptors in mice treated with metabotropic glutamate 2/3 receptor ligands. Journal of Neurochemistry. 93: 1345-52. PMID 15934953 DOI: 10.1111/J.1471-4159.2005.03141.X  0.339
2005 Simonyi A, Ngomba RT, Storto M, Catania MV, Miller LA, Youngs B, DiGiorgi-Gerevini V, Nicoletti F, Sun GY. Expression of groups I and II metabotropic glutamate receptors in the rat brain during aging. Brain Research. 1043: 95-106. PMID 15862522 DOI: 10.1016/J.Brainres.2005.02.046  0.324
2005 Cvetkovic I, Al-Abed Y, Miljkovic D, Maksimovic-Ivanic D, Roth J, Bacher M, Lan HY, Nicoletti F, Stosic-Grujicic S. Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes. Endocrinology. 146: 2942-51. PMID 15790730 DOI: 10.1210/En.2004-1393  0.33
2005 Bittencourt MDC, Herren S, Graber P, Vilbois F, Pasquali C, Berney C, Plitz T, Nicoletti F, Kosco‐Vilbois MH. Extracellular lysosome-associated membrane protein-1 (LAMP-1) mediates autoimmune disease progression in the NOD model of type 1 diabetes European Journal of Immunology. 35: 1501-1509. PMID 15789355 DOI: 10.1002/Eji.200425851  0.302
2005 Storto M, Battaglia G, Gradini R, Bruno V, Nicoletti F, Vairetti M. Mouse hepatocytes lacking mGlu5 metabotropic glutamate receptors are less sensitive to hypoxic damage. European Journal of Pharmacology. 497: 25-7. PMID 15321731 DOI: 10.1016/J.Ejphar.2004.06.023  0.345
2004 Paola RD, Marco RD, Mazzon E, Genovese T, Bendtzen K, Macrì B, Nicoletti F, Cuzzocrea S. Prevention of carrageenan-induced pleurisy in mice by anti-CD30 ligand monoclonal antibody. Clinical Immunology. 113: 64-73. PMID 15380531 DOI: 10.1016/J.Clim.2004.05.008  0.303
2004 Iorio PD, Ballerini P, Traversa U, Nicoletti F, D'Alimonte I, Kleywegt S, Werstiuk ES, Rathbone MP, Caciagli F, Ciccarelli R. The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. Glia. 46: 356-368. PMID 15095366 DOI: 10.1002/Glia.20002  0.335
2004 Frasca G, Chiechio S, Vancheri C, Nicoletti F, Copani A, Angela Sortino M. Beta-amyloid-activated cell cycle in SH-SY5Y neuroblastoma cells: correlation with the MAP kinase pathway. Journal of Molecular Neuroscience : Mn. 22: 231-6. PMID 14997017 DOI: 10.1385/Jmn:22:3:231  0.301
2004 Battaglia G, Busceti CL, Molinaro G, Biagioni F, Storto M, Fornai F, Nicoletti F, Bruno V. Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 828-35. PMID 14749427 DOI: 10.1523/Jneurosci.3831-03.2004  0.346
2004 Zuena A, Cinque C, Catalani A, Nicoletti F, Matteucci P, Adriani W, Laviola G, Casolini P. P72 NEONATAL ANOXIA: EFFECTS ON BEHAVIOUR AND GLUTAMATE RECEPTORS IN RATS Behavioural Pharmacology. 15: A29. DOI: 10.1097/00008877-200409000-00112  0.317
2003 Battaglia G, Fornai F, Busceti CL, Lembo G, Nicoletti F, De Blasi A. Alpha-1B adrenergic receptor knockout mice are protected against methamphetamine toxicity. Journal of Neurochemistry. 86: 413-21. PMID 12871582 DOI: 10.1046/J.1471-4159.2003.01867.X  0.318
2003 Caricasole A, Ferraro T, Iacovelli L, Barletta E, Caruso A, Melchiorri D, Terstappen GC, Nicoletti F. Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins. The Journal of Biological Chemistry. 278: 37024-31. PMID 12857724 DOI: 10.1074/Jbc.M300191200  0.321
2003 Battaglia G, Busceti CL, Pontarelli F, Biagioni F, Fornai F, Paparelli A, Bruno V, Ruggieri S, Nicoletti F. Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Neuropharmacology. 45: 155-66. PMID 12842121 DOI: 10.1016/S0028-3908(03)00146-1  0.326
2003 D'Onofrio M, Arcella A, Bruno V, Ngomba RT, Battaglia G, Lombari V, Ragona G, Calogero A, Nicoletti F. Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells. Journal of Neurochemistry. 84: 1288-95. PMID 12614329 DOI: 10.1046/J.1471-4159.2003.01633.X  0.344
2003 Storto M, Ngomba RT, Battaglia G, Freitas I, Griffini P, Richelmi P, Nicoletti F, Vairetti M. Selective blockade of mGlu5 metabotropic glutamate receptors is protective against acetaminophen hepatotoxicity in mice. Journal of Hepatology. 38: 179-87. PMID 12547406 DOI: 10.1016/S0168-8278(02)00384-7  0.348
2003 Iacovelli L, Salvatore L, Capobianco L, Picascia A, Barletta E, Storto M, Mariggiò S, Sallese M, Porcellini A, Nicoletti F, Blasi AD. Role of G Protein-coupled Receptor Kinase 4 and β-Arrestin 1 in Agonist-stimulated Metabotropic Glutamate Receptor 1 Internalization and Activation of Mitogen-activated Protein Kinases Journal of Biological Chemistry. 278: 12433-12442. PMID 12519791 DOI: 10.1074/Jbc.M203992200  0.333
2003 Poli A, Beraudi A, Villani L, Storto M, Battaglia G, Di Giorgi Gerevini V, Cappuccio I, Caricasole A, D'Onofrio M, Nicoletti F. Group II Metabotropic Glutamate Receptors Regulate the Vulnerability to Hypoxic Brain Damage The Journal of Neuroscience. 23: 6023-6029. DOI: 10.1523/Jneurosci.23-14-06023.2003  0.323
2002 Flor PJ, Battaglia G, Nicoletti F, Gasparini F, Bruno V. Neuroprotective activity of metabotropic glutamate receptor ligands Advances in Experimental Medicine and Biology. 513: 197-223. PMID 12575822 DOI: 10.1007/978-1-4615-0123-7_7  0.335
2002 Picconi B, Pisani A, Centonze D, Battaglia G, Storto M, Nicoletti F, Bernardi G, Calabresi P. Striatal metabotropic glutamate receptor function following experimental parkinsonism and chronic levodopa treatment. Brain : a Journal of Neurology. 125: 2635-45. PMID 12429591 DOI: 10.1093/Brain/Awf269  0.356
2002 Matrisciano F, Storto M, Ngomba RT, Cappuccio I, Caricasole A, Scaccianoce S, Riozzi B, Melchiorri D, Nicoletti F. Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus. Neuropharmacology. 42: 1008-15. PMID 12128001 DOI: 10.1016/S0028-3908(02)00057-6  0.362
2002 Besong G, Battaglia G, D'Onofrio M, Di Marco R, Ngomba RT, Storto M, Castiglione M, Mangano K, Busceti CL, Nicoletti FR, Bacon K, Tusche M, Valenti O, Conn PJ, Bruno V, ... Nicoletti F, et al. Activation of group III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5403-11. PMID 12097492 DOI: 10.1523/Jneurosci.22-13-05403.2002  0.349
2002 Zaccone P, Fehérvári Z, Blanchard L, Nicoletti F, Edwards CK, Cooke A. Autoimmune thyroid disease induced by thyroglobulin and lipopolysaccharide is inhibited by soluble TNF receptor type I. European Journal of Immunology. 32: 1021-1028. PMID 11920568 DOI: 10.1002/1521-4141(200204)32:4<1021::Aid-Immu1021>3.0.Co;2-X  0.341
2002 Battaglia G, Fornai F, Busceti CL, Aloisi G, Cerrito F, De Blasi A, Melchiorri D, Nicoletti F. Selective Blockade of mGlu5 Metabotropic Glutamate Receptors Is Protective against Methamphetamine Neurotoxicity The Journal of Neuroscience. 22: 2135-2141. DOI: 10.1523/Jneurosci.22-06-02135.2002  0.357
2001 Bruno V, Battaglia G, Copani A, D'Onofrio M, Iorio PD, Blasi AD, Melchiorri D, Flor PJ, Nicoletti F. Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. Journal of Cerebral Blood Flow and Metabolism. 21: 1013-1033. PMID 11524608 DOI: 10.1097/00004647-200109000-00001  0.348
2001 Marco RD, Khademi M, Wallstrom E, Iacobaeus E, Salvaggio A, Caracappa S, Papoian R, Nicoletti F, Olsson T. Curative effects of recombinant human Interleukin-6 in DA rats with protracted relapsing experimental allergic encephalomyelitis. Journal of Neuroimmunology. 116: 168-177. PMID 11438171 DOI: 10.1016/S0165-5728(01)00301-0  0.306
2001 Storto M, Sallese M, Salvatore L, Poulet R, Condorelli DF, Dell'Albani P, Marcello MF, Romeo R, Piomboni P, Barone N, Nicoletti F, Nicoletti F, De Blasi A. Expression of metabotropic glutamate receptors in the rat and human testis. The Journal of Endocrinology. 170: 71-8. PMID 11431139 DOI: 10.1677/Joe.0.1700071  0.343
2001 Battaglia G, Bruno V, Pisani A, Centonze D, Catania MV, Calabresi P, Nicoletti F. Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission. Molecular and Cellular Neurosciences. 17: 1071-83. PMID 11414795 DOI: 10.1006/Mcne.2001.0992  0.328
2001 Bruno V, Battaglia G, Copani A, Cespédes VM, Galindo MF, Ceña V, Sánchez-Prieto J, Gasparini F, Kuhn R, Flor PJ, Nicoletti F. An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors. The European Journal of Neuroscience. 13: 1469-78. PMID 11328342 DOI: 10.1046/J.0953-816X.2001.01541.X  0.353
2001 De Blasi A, Conn PJ, Pin JP, Nicoletti F. Molecular determinants of metabotropic glutamate receptor signaling Trends in Pharmacological Sciences. 22: 114-120. PMID 11239574 DOI: 10.1016/S0165-6147(00)01635-7  0.317
2000 Storto M, Grazia Ud, Battaglia G, Felli MP, Maroder M, Gulino A, Ragona G, Nicoletti F, Screpanti I, Frati L, Calogero A. Expression of metabotropic glutamate receptors in murine thymocytes and thymic stromal cells. Journal of Neuroimmunology. 109: 112-120. PMID 10996213 DOI: 10.1016/S0165-5728(00)00269-1  0.334
2000 Frati C, Marchese C, Fisichella G, Copani A, Nasca MR, Storto M, Nicoletti F. Expression of functional mGlu5 metabotropic glutamate receptors in human melanocytes. Journal of Cellular Physiology. 183: 364-72. PMID 10797311 DOI: 10.1002/(Sici)1097-4652(200006)183:3<364::Aid-Jcp9>3.0.Co;2-X  0.347
1999 Marco RD, Khademi M, Wallstrom E, Muhallab S, Nicoletti F, Olsson T. Amelioration of Experimental Allergic Neuritis by Sodium Fusidate (Fusidin): Suppression of IFN-γ and TNF-α and Enhancement of IL-10 Journal of Autoimmunity. 13: 187-195. PMID 10479387 DOI: 10.1006/Jaut.1999.0317  0.309
1999 Panerai AE, Sacerdote P, Bianchi M, Nicoletti F, Manfredi B, Gaspani L, Bartorelli A, Ceciliani F, Ronchi S. Chronic Administration of UK‐114, a Multifunctional Emerging Protein, Modulates the Th1/Th2 Cytokine Pattern and Experimental Autoimmune Diseases Annals of the New York Academy of Sciences. 876: 229-235. PMID 10415614 DOI: 10.1111/J.1749-6632.1999.Tb07643.X  0.307
1999 Poli A, Lucchi R, Storto M, De Paolis P, Notari S, Nicoletti F, Casabona G. Predominant expression of group-II metabotropic glutamate receptors in the goldfish brain. Brain Research. 834: 142-5. PMID 10407103 DOI: 10.1016/S0006-8993(99)01518-8  0.323
1999 Xiang M, Zaccone P, Marco RD, Magro G, Mauro MD, Beltrami B, Meroni P, Nicoletti F. Prevention by rolipram of concanavalin A-induced T-cell-dependent hepatitis in mice European Journal of Pharmacology. 367: 399-404. PMID 10079016 DOI: 10.1016/S0014-2999(98)00901-7  0.324
1999 Bruno V, Battaglia G, Copani A, Casabona G, Storto M, Di Giorgi Gerevini V, Ngomba R, Nicoletti F. Metabotropic glutamate receptors and neurodegeneration. Progress in Brain Research. 116: 209-21. PMID 9932379 DOI: 10.1016/S0079-6123(08)60439-2  0.37
1998 Battaglia G, Bruno V, Ngomba RT, Grezia RD, Copani A, Nicoletti F. Selective activation of group-II metabotropic glutamate receptors is protective against excitotoxic neuronal death. European Journal of Pharmacology. 356: 271-274. PMID 9774259 DOI: 10.1016/S0014-2999(98)00551-2  0.303
1997 Sureda F, Copani A, Bruno V, Knöpfel T, Meltzger G, Nicoletti F. Metabotropic glutamate receptor agonists stimulate polyphosphoinositide hydrolysis in primary cultures of rat hepatocytes. European Journal of Pharmacology. 338: R1-2. PMID 9456004 DOI: 10.1016/S0014-2999(97)81950-4  0.326
1997 Ciccarelli R, Sureda FX, Casabona G, Iorio PD, Caruso A, Spinella F, Condorelli DF, Nicoletti F, Caciagli F. Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture. Glia. 21: 390-398. PMID 9419014 DOI: 10.1002/(Sici)1098-1136(199712)21:4<390::Aid-Glia6>3.0.Co;2-7  0.347
1997 Nicoletti F, Beltrami B, Raschi E, Marco RD, Magro G, Grasso S, Bendtzen K, Fiorelli G, Meroni PL. Protection from concanavalin A (Con A)-induced T cell-dependent hepatic lesions and modulation of cytokine release in mice by sodium fusidate. Clinical and Experimental Immunology. 110: 479-484. PMID 9409654 DOI: 10.1046/J.1365-2249.1997.4091423.X  0.3
1997 Bruno V, Sureda FX, Storto M, Casabona G, Caruso A, Knopfel T, Kuhn R, Nicoletti F. The Neuroprotective Activity of Group-II Metabotropic Glutamate Receptors Requires New Protein Synthesis and Involves a Glial–Neuronal Signaling The Journal of Neuroscience. 17: 1891-1897. DOI: 10.1523/Jneurosci.17-06-01891.1997  0.337
1996 Knopfel T, Madge D, Nicoletti F, Knöpfel T, Madge D, Nicoletti F. Overview Central & Peripheral Nervous Systems: Metabotropic glutamate receptors Expert Opinion On Therapeutic Patents. 6: 1061-1067. DOI: 10.1517/13543776.6.10.1061  0.343
1994 Nicoletti F, Zaccone P, Magro G, Barcellini W, Cavallaro V, Belli G, Cocuzza C, Marco RD, Meroni PL. The effects of thymopentin on the development of SLE-like syndrome in the MRL/lpr-lpr mouse. Scandinavian Journal of Immunology. 40: 549-556. PMID 7973460 DOI: 10.1111/J.1365-3083.1994.Tb03503.X  0.317
1993 Nicoletti F, Borghi MO, Meroni PL, Barcellini W, Fain C, Di Marco R, Menta R, Schorlemmer HU, Bruno G, Magro G. Prevention of cyclophosphamide-induced diabetes in the NOD/WEHI mouse with deoxyspergualin. Clinical and Experimental Immunology. 91: 232-6. PMID 8428390 DOI: 10.1111/J.1365-2249.1993.Tb05888.X  0.305
1993 Marco RD, Carrabba I, Cavallaro V, Zaccone P, Stazzone C, Franco S, Cocuzza C, Nicoletti G, Nicoletti F. The Effect of Cefepime on Some Immune Parameters In Vitro: Lack of Interference with Mitogen-Induced Lymphoproliferation, Immunoglobulin Synthesis, IFN-Gamma and IL-2 Secretion and IL-2 Receptor Expression Journal of Chemotherapy. 5: 297-301. PMID 8106902 DOI: 10.1080/1120009X.1993.11739248  0.302
1993 Condorelli DF, Dell'Albani P, Amico C, Kaczmarek L, Nicoletti F, Lukasiuk K, Stella AM. Induction of primary response genes by excitatory amino acid receptor agonists in primary astroglial cultures. Journal of Neurochemistry. 60: 877-85. PMID 8094745 DOI: 10.1111/J.1471-4159.1993.Tb03232.X  0.341
1993 Caruso S, Agnello C, Campo MG, Nicoletti F. Oxytocin reduces the activity of N-methyl — D — aspartate receptors in cultured neurons Journal of Endocrinological Investigation. 16: 921-924. PMID 7908300 DOI: 10.1007/Bf03348959  0.333
1992 Casabona G, Bruno V, Catania MV, Sortino MA, Nicoletti F, Scapagnini U, Canonico PL. Thyrotropin releasing hormone (TRH) and its analog, RGH-2202, accelerate maturation of cerebellar neurons in vitro. Brain Research. Developmental Brain Research. 69: 179-83. PMID 1424094 DOI: 10.1016/0165-3806(92)90157-R  0.308
1992 Favit A, Nicoletti F, Scapagnini U, Canonico PL. Ubiquinone protects cultured neurons against spontaneous and excitotoxin- induced degeneration Journal of Cerebral Blood Flow and Metabolism. 12: 638-645. PMID 1352303 DOI: 10.1038/Jcbfm.1992.88  0.323
1991 Sortino MA, Nicoletti F, Canonico PL. 'Metabotropic' glutamate receptors in rat hypothalamus: characterization and developmental profile Developmental Brain Research. 61: 169-172. PMID 1684312 DOI: 10.1016/0165-3806(91)90128-6  0.341
1991 Favit A, Fiore L, Nicoletti F, Canonico PL. Estrogen modulates stimulation of inositol phospholipid hydrolysis by norepinephrine in rat brain slices Brain Research. 555: 65-69. PMID 1657297 DOI: 10.1016/0006-8993(91)90860-X  0.302
1989 Nicoletti F, Canonico PL. Glycine Potentiates the Stimulation of Inositol Phospholipid Hydrolysis by Excitatory Amino Acids in Primary Cultures of Cerebellar Neurons Journal of Neurochemistry. 53: 724-727. PMID 2569502 DOI: 10.1111/J.1471-4159.1989.Tb11764.X  0.312
1989 Nicoletti F, Canonico PL, Favit A, Nicoletti G, Albanese V. Receptor-mediated stimulation of inositol phospholipid hydrolysis in human brain European Journal of Pharmacology. 160: 299-301. PMID 2547631 DOI: 10.1016/0014-2999(89)90504-9  0.324
1988 Nicoletti F, Wroblewski JT, Fadda E, Costa E. Pertussis toxin inhibits signal transduction at a specific metabolotropic glutamate receptor in primary cultures of cerebellar granule cells. Neuropharmacology. 27: 551-6. PMID 2843781 DOI: 10.1016/0028-3908(88)90174-8  0.331
1988 Bruno V, Catania MV, Canonico PL, Nicoletti F, Scapagnini U. Indolpyruvic acid (IPA) acts as an antagonist of Mg2+-sensitive glutamate receptors in cerebellar neurons Pharmacological Research Communications. 20: 59. DOI: 10.1016/S0031-6989(88)80189-9  0.316
1987 Wroblewski JT, Nicoletti F, Fadda E, Costa E. Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors. Proceedings of the National Academy of Sciences of the United States of America. 84: 5068-72. PMID 3037532 DOI: 10.1073/Pnas.84.14.5068  0.34
1987 Novelli A, Nicoletti F, Wroblewski JT, Alho H, Costa E, Guidotti A. Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 40-7. PMID 2879898 DOI: 10.1523/Jneurosci.07-01-00040.1987  0.479
1987 Nicoletti F, Wroblewski JT, Costa E. Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells. Journal of Neurochemistry. 48: 967-73. PMID 2879893 DOI: 10.1111/J.1471-4159.1987.Tb05611.X  0.314
1987 Novelli A, Nicoletti F, Wroblewski J, Alho H, Costa E, Guidotti A. Excitatory amino acid receptors coupled with guanylate cyclase in primary cultures of cerebellar granule cells The Journal of Neuroscience. 7: 40-47. DOI: 10.1523/JNEUROSCI.07-01-00040.1987  0.408
1986 Nicoletti F, Wroblewski JT, Novelli A, Guidotti A, Costa E. Excitatory amino acid signal transduction in cerebellar cell cultures. Functional Neurology. 1: 345-9. PMID 2886406  0.41
1986 Nicoletti F, Iadarola MJ, Wroblewski JT, Costa E. Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors. Proceedings of the National Academy of Sciences of the United States of America. 83: 1931-5. PMID 2869493 DOI: 10.1073/Pnas.83.6.1931  0.303
1986 Nicoletti F, Wroblewski J, Novelli A, Alho H, Guidotti A, Costa E. The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells The Journal of Neuroscience. 6: 1905-1911. DOI: 10.1523/Jneurosci.06-07-01905.1986  0.466
1985 Nicoletti F, Speciale C, Sortino MA, Panetta MS, Giorgio RMD, Canonico PL. Estrogen effects of nigral glutamic acid decarboxylase activity: A possible role for catecholestrogen European Journal of Pharmacology. 115: 297-300. PMID 2998827 DOI: 10.1016/0014-2999(85)90703-4  0.305
1983 Nicoletti F, Clementi G, Prato A, Canonico PL, Rampello L, Patti F, Giorgio RMD, Scapagnini U. Effects of hyper- and hypoprolactinemia on glutamate decarboxylase activity in medial basal hypothalamus of male rat Neuroendocrinology. 36: 13-16. PMID 6828202 DOI: 10.1159/000123430  0.315
1982 Nicoletti F, Canonico PL, Patti F, Rampello L, Condorelli DF, Giammona G, Giorgio RMD, Scapagnini U. Sulpiride effects on nigral and striatal glutamic acid decarboxylase activity: A possible involvement of prolactin European Journal of Pharmacology. 77: 131-135. PMID 7060633 DOI: 10.1016/0014-2999(82)90007-3  0.315
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