Jon David Gaffaney, Ph.D. - Publications

Affiliations: 
Neuroscience University of Wisconsin, Madison, Madison, WI 
Area:
membrane fusion

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Chang CW, Chiang CW, Gaffaney JD, Chapman ER, Jackson MB. Lipid-anchored synaptobrevin provides little or no support for exocytosis or liposome fusion. The Journal of Biological Chemistry. PMID 26663078 DOI: 10.1074/Jbc.M115.701169  0.623
2015 Xue R, Gaffaney JD, Chapman ER. Structural elements that underlie Doc2β function during asynchronous synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. 112: E4316-25. PMID 26195798 DOI: 10.1073/Pnas.1502288112  0.703
2014 Gaffaney JD, Xue R, Chapman ER. Mutations that disrupt Ca²⁺-binding activity endow Doc2β with novel functional properties during synaptic transmission. Molecular Biology of the Cell. 25: 481-94. PMID 24356452 DOI: 10.1091/Mbc.E13-10-0571  0.695
2014 Gaffaney JD, Shetty M, Felts B, Pramod AB, Foster JD, Henry LK, Vaughan RA. Antagonist-induced conformational changes in dopamine transporter extracellular loop two involve residues in a potential salt bridge. Neurochemistry International. 73: 16-26. PMID 24269640 DOI: 10.1016/J.Neuint.2013.11.003  0.657
2012 Yao J, Kwon SE, Gaffaney JD, Dunning FM, Chapman ER. Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles. Nature Neuroscience. 15: 243-9. PMID 22197832 DOI: 10.1038/Nn.3013  0.695
2011 Yao J, Gaffaney JD, Kwon SE, Chapman ER. Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release. Cell. 147: 666-77. PMID 22036572 DOI: 10.1016/J.Cell.2011.09.046  0.752
2011 Hui E, Gaffaney JD, Wang Z, Johnson CP, Evans CS, Chapman ER. Mechanism and function of synaptotagmin-mediated membrane apposition. Nature Structural & Molecular Biology. 18: 813-21. PMID 21642967 DOI: 10.1038/Nsmb.2075  0.739
2008 Gaffaney JD, Dunning FM, Wang Z, Hui E, Chapman ER. Synaptotagmin C2B domain regulates Ca2+-triggered fusion in vitro: critical residues revealed by scanning alanine mutagenesis. The Journal of Biological Chemistry. 283: 31763-75. PMID 18784080 DOI: 10.1074/Jbc.M803355200  0.742
2008 Parnas ML, Gaffaney JD, Zou MF, Lever JR, Newman AH, Vaughan RA. Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites. Molecular Pharmacology. 73: 1141-50. PMID 18216182 DOI: 10.1124/Mol.107.043679  0.713
2005 Vaughan RA, Parnas ML, Gaffaney JD, Lowe MJ, Wirtz S, Pham A, Reed B, Dutta SM, Murray KK, Justice JB. Affinity labeling the dopamine transporter ligand binding site. Journal of Neuroscience Methods. 143: 33-40. PMID 15763134 DOI: 10.1016/J.Jneumeth.2004.09.022  0.706
2004 Gaffaney JD, Vaughan RA. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter. Molecular Pharmacology. 65: 692-701. PMID 14978248 DOI: 10.1124/Mol.65.3.692  0.657
2001 Vaughan RA, Gaffaney JD, Lever JR, Reith ME, Dutta AK. Dual incorporation of photoaffinity ligands on dopamine transporters implicates proximity of labeled domains. Molecular Pharmacology. 59: 1157-64. PMID 11306699 DOI: 10.1124/Mol.59.5.1157  0.671
2001 Dutta AK, Fei XS, Vaughan RA, Gaffaney JD, Wang N, Lever JR, Reith ME. Design, synthesis, and characterization of a novel, 4-[2-(diphenylmethoxy)ethyl]-1-benzyl piperidine-based, dopamine transporter photoaffinity label. Life Sciences. 68: 1839-49. PMID 11292062 DOI: 10.1016/S0024-3205(01)00981-X  0.625
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