Luca Magnani, Ph.D. - Publications

Affiliations: 
2008 Animal Sciences Purdue University, West Lafayette, IN, United States 
Area:
Animal Physiology Biology, Molecular Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Borgoni S, Sofyalı E, Soleimani M, Wilhelm H, Müller-Decker K, Will R, Noronha A, Beumers L, Verschure PJ, Yarden Y, Magnani L, van Kampen AHC, Moerland PD, Wiemann S. Time-Resolved Profiling Reveals ATF3 as a Novel Mediator of Endocrine Resistance in Breast Cancer. Cancers. 12. PMID 33050633 DOI: 10.3390/cancers12102918  0.337
2020 Acar A, Nichol D, Fernandez-Mateos J, Cresswell GD, Barozzi I, Hong SP, Trahearn N, Spiteri I, Stubbs M, Burke R, Stewart A, Caravagna G, Werner B, Vlachogiannis G, Maley CC, ... Magnani L, et al. Exploiting evolutionary steering to induce collateral drug sensitivity in cancer. Nature Communications. 11: 1923. PMID 32317663 DOI: 10.1038/S41467-020-15596-Z  0.317
2020 Cresswell GD, Nichol D, Spiteri I, Tari H, Zapata L, Heide T, Maley CC, Magnani L, Schiavon G, Ashworth A, Barry P, Sottoriva A. Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking. Nature Communications. 11: 1446. PMID 32221288 DOI: 10.1038/S41467-020-15047-9  0.366
2020 Zwart W, Magnani L, Natrajan R. Decision letter: Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer Elife. DOI: 10.7554/Elife.58810.Sa1  0.344
2020 Zoppoli G, Garuti A, Belfiore A, Bonizzi G, Ferrando L, Vingiani A, Colleoni M, Munzone E, Magnani L, Viale G, Ballestrero A, Pruneri G. Abstract PD8-04: Ultra-deep multigene profiling of matched primary and metastatic hormone receptor positive breast cancer patients relapsed after adjuvant endocrine treatment reveals novel aberrations in the estrogen receptor pathway Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Pd8-04  0.398
2020 Rocca A, Ravaioli S, Fonzi E, Barozzi I, Perone Y, Magnani L, Pirini F, Martinelli G, Bravaccini S. Abstract P4-07-06: Breast cancer subtype classification using NanoString and RNAseq technologies Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-07-06  0.408
2020 Magnani L, Barozzi I, Hong S. Abstract ES4-2: Single cell transcriptomics reveals multi-step adaptations to endocrine therapy Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Es4-2  0.395
2019 Hong SP, Chan TE, Lombardo Y, Corleone G, Rotmensz N, Bravaccini S, Rocca A, Pruneri G, McEwen KR, Coombes RC, Barozzi I, Magnani L. Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy. Nature Communications. 10: 3840. PMID 31477698 DOI: 10.1038/S41467-019-11721-9  0.368
2019 Perone Y, Farrugia AJ, Rodríguez-Meira A, Győrffy B, Ion C, Uggetti A, Chronopoulos A, Marrazzo P, Faronato M, Shousha S, Davies C, Steel JH, Patel N, Del Rio Hernandez A, Coombes C, ... ... Magnani L, et al. Author Correction: SREBP1 drives keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer. Nature Communications. 10: 3791. PMID 31427580 DOI: 10.1038/S41467-019-11801-W  0.355
2019 Perone Y, Farrugia AJ, Meira AR, Győrffy B, Ion C, Uggetti A, Chronopoulos A, Marrazzo P, Faronato M, Shousha S, Davies C, Steel JH, Patel N, Del Rio Hernandez A, Coombes C, ... ... Magnani L, et al. SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer. Nature Communications. 10: 2115. PMID 31073170 DOI: 10.1038/S41467-019-09676-Y  0.437
2019 Varghese V, Magnani L, Harada-Shoji N, Mauri F, Szydlo RM, Yao S, Lam EW, Kenny LM. FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expression. Scientific Reports. 9: 1505. PMID 30728402 DOI: 10.1038/S41598-018-38017-0  0.382
2019 Ferrari N, Ranftl R, Chicherova I, Slaven ND, Moeendarbary E, Farrugia AJ, Lam M, Semiannikova M, Westergaard MCW, Tchou J, Magnani L, Calvo F. Dickkopf-3 links HSF1 and YAP/TAZ signalling to control aggressive behaviours in cancer-associated fibroblasts. Nature Communications. 10: 130. PMID 30631061 DOI: 10.1038/S41467-018-07987-0  0.374
2019 Perone Y, Rodríguez Meira A, Farruggia A, Győrffy B, Ion C, Pruneri G, Lim A, Calvo F, Magnani L. OR34-2 SREBP1 Drives KRT80-Dependent Cytoskeletal Changes and Invasive Behaviour in Endocrine-Resistant ERα Breast Cancer Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or34-2  0.375
2018 Patten DK, Corleone G, Győrffy B, Perone Y, Slaven N, Barozzi I, Erdős E, Saiakhova A, Goddard K, Vingiani A, Shousha S, Pongor LS, Hadjiminas DJ, Schiavon G, Barry P, ... ... Magnani L, et al. Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer. Nature Medicine. PMID 30038216 DOI: 10.1038/S41591-018-0091-X  0.455
2018 Noberini R, Osti D, Miccolo C, Richichi C, Lupia M, Corleone G, Hong SP, Colombo P, Pollo B, Fornasari L, Pruneri G, Magnani L, Cavallaro U, Chiocca S, Minucci S, et al. Extensive and systematic rewiring of histone post-translational modifications in cancer model systems. Nucleic Acids Research. PMID 29618087 DOI: 10.1093/Nar/Gky224  0.373
2017 Magnani L, Frigè G, Gadaleta RM, Corleone G, Fabris S, Kempe MH, Vershure PJ, Barozzi I, Vircillo V, Hong SP, Perone Y, Saini M, Trumpp A, Viale G, Neri A, et al. Corrigendum: Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer. Nature Genetics. 49: 970. PMID 28546573 DOI: 10.1038/Ng0617-970B  0.339
2017 Magnani L, Frigè G, Gadaleta RM, Corleone G, Fabris S, Kempe MH, Vershure PJ, Barozzi I, Vircillo V, Hong SP, Perone Y, Saini M, Trumpp A, Viale G, Neri A, et al. Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer. Nature Genetics. PMID 28112739 DOI: 10.1038/Ng.3773  0.415
2016 Harrod A, Fulton J, Nguyen VT, Periyasamy M, Ramos-Garcia L, Lai CF, Metodieva G, de Giorgio A, Williams RL, Santos DB, Gomez PJ, Lin ML, Metodiev MV, Stebbing J, Castellano L, ... Magnani L, et al. Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene. PMID 27748765 DOI: 10.1038/Onc.2016.382  0.374
2016 Menyhárt O, Harami-Papp H, Sukumar S, Schäfer R, Magnani L, de Barrios O, Győrffy B. Guidelines For The Selection of Functional Assays To Evaluate The Hallmarks of Cancer. Biochimica Et Biophysica Acta. PMID 27742530 DOI: 10.1016/J.Bbcan.2016.10.002  0.335
2016 Patel H, Abduljabbar R, Lai CF, Periyasamy M, Harrod A, Gemma C, Steel J, Patel N, Busonero C, Jerjees D, Remenyi J, Smith S, Gomm JJ, Magnani L, Gyorffy B, et al. CDK7, cyclin H and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor- positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27301701 DOI: 10.1158/1078-0432.Ccr-15-1104  0.399
2016 Bhat-Nakshatri P, Goswami CP, Badve S, Magnani L, Lupien M, Nakshatri H. Molecular Insights of Pathways Resulting From Two Common PIK3CA Mutations in Breast Cancer. Cancer Research. PMID 27197157 DOI: 10.1158/0008-5472.Can-15-3174  0.602
2016 Perone Y, Magnani L. Going off the grid: ERα breast cancer beyond estradiol. Journal of Molecular Endocrinology. PMID 27151575 DOI: 10.1530/Jme-16-0062  0.409
2015 Chen X, Jung JG, Shajahan-Haq AN, Clarke R, Shih IM, Wang Y, Magnani L, Wang TL, Xuan J. ChIP-BIT: Bayesian inference of target genes using a novel joint probabilistic model of ChIP-seq profiles. Nucleic Acids Research. PMID 26704972 DOI: 10.1093/Nar/Gkv1491  0.333
2015 Nguyen VT, Barozzi I, Faronato M, Lombardo Y, Steel JH, Patel N, Darbre P, Castellano L, Győrffy B, Woodley L, Meira A, Patten DK, Vircillo V, Periyasamy M, Ali S, ... ... Magnani L, et al. Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion. Nature Communications. 6: 10044. PMID 26610607 DOI: 10.1038/Ncomms10044  0.374
2015 Periyasamy M, Patel H, Lai CF, Nguyen VT, Nevedomskaya E, Harrod A, Russell R, Remenyi J, Ochocka AM, Thomas RS, Fuller-Pace F, Győrffy B, Caldas C, Navaratnam N, Carroll JS, ... ... Magnani L, et al. APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer. Cell Reports. 13: 108-21. PMID 26411678 DOI: 10.1016/J.Celrep.2015.08.066  0.42
2015 Magnani L, Patten DK, Nguyen VT, Hong SP, Steel JH, Patel N, Lombardo Y, Faronato M, Gomes AR, Woodley L, Page K, Guttery D, Primrose L, Fernandez Garcia D, Shaw J, et al. The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer. Oncotarget. PMID 26215677 DOI: 10.18632/Oncotarget.4243  0.635
2015 Xu Y, Zhang H, Nguyen VT, Angelopoulos N, Nunes J, Reid A, Buluwela L, Magnani L, Stebbing J, Giamas G. LMTK3 Represses Tumor Suppressor-like Genes through Chromatin Remodeling in Breast Cancer. Cell Reports. 12: 837-49. PMID 26212333 DOI: 10.1016/J.Celrep.2015.06.073  0.409
2015 Faronato M, Nguyen VT, Patten DK, Lombardo Y, Steel JH, Patel N, Woodley L, Shousha S, Pruneri G, Coombes RC, Magnani L. DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through notch hyper-activation. Oncotarget. PMID 26093085 DOI: 10.18632/Oncotarget.4164  0.434
2015 Okamoto OK, Matheu A, Magnani L. Stem Cells in Translational Cancer Research. Stem Cells International. 2015: 281072. PMID 26078763 DOI: 10.1155/2015/281072  0.362
2015 Varghese V, Magnani L, Harada N, Eric LW, Kenny L. Abstract A54: Inhibition of FOXM1 by thiostrepton increases sensitivity to 5-fluorouracil (5-FU) by downregulating thymidylate synthase (TS) in colorectal cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-A54  0.385
2015 Nakshatri H, Goswami C, Badve S, Magnani L, Lupien M, Bhat-Nakshatri P. Abstract P3-05-15: Divergent activation of AKT1 and AKT2 isoforms downstream of PI3K mutation impacts response of breast cancer cells to estradiol and PI3K inhibitors Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-15  0.619
2014 Brown R, Curry E, Magnani L, Wilhelm-Benartzi CS, Borley J. Poised epigenetic states and acquired drug resistance in cancer. Nature Reviews. Cancer. 14: 747-53. PMID 25253389 DOI: 10.1038/Nrc3819  0.321
2014 Jangal M, Couture JP, Bianco S, Magnani L, Mohammed H, Gévry N. The transcriptional co-repressor TLE3 suppresses basal signaling on a subset of estrogen receptor α target genes. Nucleic Acids Research. 42: 11339-48. PMID 25223786 DOI: 10.1093/Nar/Gku791  0.377
2014 Lombardo Y, Faronato M, Filipovic A, Vircillo V, Magnani L, Coombes RC. Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells. Breast Cancer Research : Bcr. 16: R62. PMID 24919951 DOI: 10.1186/Bcr3675  0.409
2014 Bianco S, Brunelle M, Jangal M, Magnani L, Gévry N. LRH-1 governs vital transcriptional programs in endocrine-sensitive and -resistant breast cancer cells. Cancer Research. 74: 2015-25. PMID 24520076 DOI: 10.1158/0008-5472.Can-13-2351  0.442
2014 Gadaleta RM, Magnani L. Nuclear receptors and chromatin: an inducible couple. Journal of Molecular Endocrinology. 52: R137-49. PMID 24363438 DOI: 10.1530/Jme-13-0170  0.314
2014 Magnani L, Lupien M. Chromatin and epigenetic determinants of estrogen receptor alpha (ESR1) signaling. Molecular and Cellular Endocrinology. 382: 633-41. PMID 23684889 DOI: 10.1016/J.Mce.2013.04.026  0.592
2014 Varghese V, Magnani L, Harada N, Mauri FA, Lam EW, Kenny LM. Abstract LB-220: Forkhead box transciption factor M1 (FOXM1) plays a critical role in colorectal cancer resistance by regulating thymidylate synthase (TS) Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-220  0.401
2013 Magnani L, Stoeck A, Zhang X, Lánczky A, Mirabella AC, Wang TL, Gyorffy B, Lupien M. Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: E1490-9. PMID 23576735 DOI: 10.1073/Pnas.1219992110  0.688
2012 Magnani L, Brunelle M, Gévry N, Lupien M. Chromatin landscape and endocrine response in breast cancer. Epigenomics. 4: 675-83. PMID 23244312 DOI: 10.2217/Epi.12.64  0.636
2012 Magnani L, Carroll J, Zwart W, Palmieri C. ChIPing away at breast cancer. The Lancet. Oncology. 13: 1185-7. PMID 23182190 DOI: 10.1016/S1470-2045(12)70511-9  0.377
2012 Thiaville MM, Stoeck A, Chen L, Wu RC, Magnani L, Oidtman J, Shih IeM, Lupien M, Wang TL. Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites. Plos One. 7: e36054. PMID 22567123 DOI: 10.1371/Journal.Pone.0036054  0.615
2012 Wang X, Park KE, Koser S, Liu S, Magnani L, Cabot RA. KPNA7, an oocyte- and embryo-specific karyopherin α subtype, is required for porcine embryo development. Reproduction, Fertility, and Development. 24: 382-91. PMID 22281085 DOI: 10.1071/Rd11119  0.338
2011 Magnani L, Ballantyne EB, Zhang X, Lupien M. PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer. Plos Genetics. 7: e1002368. PMID 22125492 DOI: 10.1371/Journal.Pgen.1002368  0.693
2011 Magnani L, Eeckhoute J, Lupien M. Pioneer factors: directing transcriptional regulators within the chromatin environment. Trends in Genetics : Tig. 27: 465-74. PMID 21885149 DOI: 10.1016/J.Tig.2011.07.002  0.571
2010 Wang K, Sengupta S, Magnani L, Wilson CA, Henry RW, Knott JG. Brg1 is required for Cdx2-mediated repression of Oct4 expression in mouse blastocysts. Plos One. 5: e10622. PMID 20485553 DOI: 10.1093/Biolreprod/83.S1.33  0.385
2010 Park KE, Johnson CM, Magnani L, Wang X, Biancardi MN, Cabot RA. Global H3K9 dimethylation status is not affected by transcription, translation, or DNA replication in porcine zygotes. Molecular Reproduction and Development. 77: 420-9. PMID 20108327 DOI: 10.1002/Mrd.21156  0.348
2009 Park KE, Magnani L, Cabot RA. Differential remodeling of mono- and trimethylated H3K27 during porcine embryo development. Molecular Reproduction and Development. 76: 1033-42. PMID 19536841 DOI: 10.1002/Mrd.21061  0.379
2009 Xing X, Magnani L, Lee K, Wang C, Cabot RA, Machaty Z. Gene expression and development of early pig embryos produced by serial nuclear transfer. Molecular Reproduction and Development. 76: 555-63. PMID 18951379 DOI: 10.1002/Mrd.20974  0.345
2009 Magnani L, Cabot RA. Manipulation of SMARCA2 and SMARCA4 transcript levels in porcine embryos differentially alters development and expression of SMARCA1, SOX2, NANOG, and EIF1. Reproduction (Cambridge, England). 137: 23-33. PMID 18845624 DOI: 10.1530/Rep-08-0335  0.365
2009 Wang X, Magnani L, Cabot R. 198 Karyopherin Alpha Expression In Porcine Oocytes And Embryos Produced By In Vitro Fertilization Reproduction, Fertility and Development. 21: 197-198. DOI: 10.1071/Rdv21N1Ab198  0.648
2009 Biancardi MN, Magnani L, Johnson CM, Cabot RA. 178 Transcript Abundance Of Methyltransferases Specific For H3K9 Differ At Discrete Stages Of Porcine Oocyte And Cleavage Stage Embryo Development Reproduction, Fertility and Development. 21: 188-188. DOI: 10.1071/Rdv21N1Ab178  0.366
2008 Magnani L, Johnson CM, Cabot RA. Expression of eukaryotic elongation initiation factor 1A differentially marks zygotic genome activation in biparental and parthenogenetic porcine embryos and correlates with in vitro developmental potential. Reproduction, Fertility, and Development. 20: 818-25. PMID 18842184 DOI: 10.1071/Rd08072  0.364
2008 Magnani L, Cabot RA. In vitro and in vivo derived porcine embryos possess similar, but not identical, patterns of Oct4, Nanog, and Sox2 mRNA expression during cleavage development. Molecular Reproduction and Development. 75: 1726-35. PMID 18425776 DOI: 10.1002/Mrd.20915  0.339
2008 Magnani L, Lee K, Fodor WL, Machaty Z, Cabot RA. Developmental capacity of porcine nuclear transfer embryos correlate with levels of chromatin-remodeling transcripts in donor cells. Molecular Reproduction and Development. 75: 766-76. PMID 18246531 DOI: 10.1002/Mrd.20818  0.364
2008 Park K, Magnani L, Cabot R. Expression Patterns of H3/K27 Methylation Mediating Genes in Porcine Embryos. Biology of Reproduction. 78: 96-97. DOI: 10.1093/Biolreprod/78.S1.96C  0.613
2008 Magnani L, Cabot R. Ectopic Expression of Brahma in Porcine Embryos Induces Developmental Arrest and Alters Expression of SNF2L. Biology of Reproduction. 78: 72-72. DOI: 10.1093/Biolreprod/78.S1.72  0.614
2007 Magnani L, Cabot RA. Developmental arrest induced in cleavage stage porcine embryos following microinjection of mRNA encoding Brahma (Smarca 2), a chromatin remodeling protein. Molecular Reproduction and Development. 74: 1262-7. PMID 17342730 DOI: 10.1002/Mrd.20710  0.364
2007 Biancardi M, Cabot R, Magnani L. The Histone Methyltransferase G9A Adopts A Nuclear Localization In Cleaved Porcine Embryos, But Rarely In Pronuclear Stage Embryos Biology of Reproduction. 77: 89-89. DOI: 10.1093/Biolreprod/77.S1.89A  0.618
2007 Johnson C, Magnani L, Cabot R. Histone Methyltransferase Glp Shows Reduced Amount Of Transcript From The Gv-Stage Oocyte To The 8-Cell Stage In Porcine Parthenogenetic Embryos Biology of Reproduction. 77: 113-113. DOI: 10.1093/Biolreprod/77.S1.113A  0.636
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