Year |
Citation |
Score |
2024 |
Tewari M, Michalski S, Egan TM. Modulation of Microglial Function by ATP-Gated P2X7 Receptors: Studies in Rat, Mice and Human. Cells. 13. PMID 38247852 DOI: 10.3390/cells13020161 |
0.464 |
|
2022 |
Liang X, Janks L, Egan TM. Using Whole-Cell Electrophysiology and Patch-Clamp Photometry to Characterize P2X7 Receptor Currents. Methods in Molecular Biology (Clifton, N.J.). 2510: 217-237. PMID 35776327 DOI: 10.1007/978-1-0716-2384-8_11 |
0.414 |
|
2019 |
Liang X, Samways DSK, Cox J, Egan TM. Ca flux through splice variants of the ATP-gated ionotropic receptor P2X7 is regulated by its cytoplasmic N terminus. The Journal of Biological Chemistry. PMID 31248985 DOI: 10.1074/jbc.RA119.009666 |
0.42 |
|
2019 |
Janks L, Sprague RS, Egan TM. ATP-Gated P2X7 Receptors Require Chloride Channels To Promote Inflammation in Human Macrophages. Journal of Immunology (Baltimore, Md. : 1950). 202: 883-898. PMID 30598517 DOI: 10.4049/jimmunol.1801101 |
0.447 |
|
2018 |
Janks L, Sharma CVR, Egan TM. A central role for P2X7 receptors in human microglia. Journal of Neuroinflammation. 15: 325. PMID 30463629 DOI: 10.1186/s12974-018-1353-8 |
0.407 |
|
2017 |
Jin H, Han J, Resing D, Liu H, Yue X, Miller RL, Schoch KM, Miller TM, Perlmutter JS, Egan TM, Tu Z. Synthesis and in vitro characterization of a P2×7 radioligand [123I]TZ6019 and its response to neuroinflammatory in a mouse model of Alzheimer Disease. European Journal of Pharmacology. PMID 29225193 DOI: 10.1016/J.Ejphar.2017.12.006 |
0.346 |
|
2016 |
Migita K, Ozaki T, Shimoyama S, Yamada J, Nikaido Y, Furukawa T, Shiba Y, Egan TM, Ueno S. HSP90 regulation of P2X7 receptor function requires an intact cytoplasmic C-terminus. Molecular Pharmacology. PMID 27301716 DOI: 10.1124/mol.115.102988 |
0.52 |
|
2015 |
Liang X, Samways DS, Wolf K, Bowles EA, Richards JP, Bruno J, Dutertre S, DiPaolo RJ, Egan TM. Quantifying Ca2+ current and permeability in ATP-gated P2X7 receptors. The Journal of Biological Chemistry. 290: 7930-42. PMID 25645917 DOI: 10.1074/Jbc.M114.627810 |
0.409 |
|
2015 |
Liang X, Samways DS, Egan TM. Quantitative Measure of Ca2+ Current and Permeability in ATP-Gated P2X7 Receptors Biophysical Journal. 108: 288a-289a. DOI: 10.1016/j.bpj.2014.11.1575 |
0.448 |
|
2014 |
Xu J, Chai H, Ehinger K, Egan TM, Srinivasan R, Frick M, Khakh BS. Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin. The Journal of General Physiology. 144: 81-104. PMID 24935743 DOI: 10.1085/Jgp.201411169 |
0.472 |
|
2014 |
Samways DS, Li Z, Egan TM. Principles and properties of ion flow in P2X receptors. Frontiers in Cellular Neuroscience. 8: 6. PMID 24550775 DOI: 10.3389/fncel.2014.00006 |
0.496 |
|
2013 |
Woods AS, Jackson SN, Lewis EK, Egan T, Muller L, Tabet JC, Schultz JA. MALDI/post ionization-ion mobility mass spectrometry of noncovalent complexes of dopamine receptors' epitopes. Journal of Proteome Research. 12: 1668-77. PMID 23469763 DOI: 10.1021/Pr301004W |
0.304 |
|
2012 |
Samways DS, Khakh BS, Egan TM. Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals. The Journal of Biological Chemistry. 287: 7594-602. PMID 22219189 DOI: 10.1074/Jbc.M111.322461 |
0.443 |
|
2011 |
Samways DS, Khakh BS, Dutertre S, Egan TM. Preferential use of unobstructed lateral portals as the access route to the pore of human ATP-gated ion channels (P2X receptors). Proceedings of the National Academy of Sciences of the United States of America. 108: 13800-5. PMID 21808018 DOI: 10.1073/Pnas.1017550108 |
0.4 |
|
2010 |
Goodnow RA, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, ... ... Egan T, et al. Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1. Journal of Medicinal Chemistry. 53: 3502-16. PMID 20380377 DOI: 10.1021/Jm1001919 |
0.305 |
|
2010 |
Toulme E, Garcia A, Samways D, Egan TM, Carson MJ, Khakh BS. P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin. The Journal of General Physiology. 135: 333-53. PMID 20231374 DOI: 10.1083/Jcb1892Oia7 |
0.326 |
|
2010 |
Migita K, Egan TM, Yamada J, Tomiyama M, Ueno S. The regulatory site of pore dilation and current facilitation in P2X7 receptor Neuroscience Research. 68: e110. DOI: 10.1016/j.neures.2010.07.2054 |
0.369 |
|
2010 |
Samways DS, Egan TM. Redox Modulation of ATP-Gated P2X7 Currents Biophysical Journal. 98: 702a. DOI: 10.1016/j.bpj.2009.12.3851 |
0.347 |
|
2010 |
Samways DS, Egan TM. Ca2+ Inhibition of Cation Conductance through TRPV1 Receptors Biophysical Journal. 98: 342a-343a. DOI: 10.1016/j.bpj.2009.12.1855 |
0.335 |
|
2010 |
Li Z, Harris S, Egan TM. P2X Receptors Encyclopedia of Neuroscience. 349-354. DOI: 10.1016/B978-008045046-9.01246-8 |
0.46 |
|
2009 |
Samways DS, Harkins AB, Egan TM. Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry. Cell Calcium. 45: 319-25. PMID 19185346 DOI: 10.1016/j.ceca.2008.12.002 |
0.386 |
|
2008 |
Samways DS, Khakh BS, Egan TM. Tunable calcium current through TRPV1 receptor channels. The Journal of Biological Chemistry. 283: 31274-8. PMID 18775990 DOI: 10.1074/Jbc.C800131200 |
0.418 |
|
2008 |
Samways DS, Migita K, Li Z, Egan TM. On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor. The Journal of Biological Chemistry. 283: 5110-7. PMID 18048351 DOI: 10.1074/jbc.M708713200 |
0.55 |
|
2007 |
Samways DS, Egan TM. Acidic amino acids impart enhanced Ca2+ permeability and flux in two members of the ATP-gated P2X receptor family. The Journal of General Physiology. 129: 245-56. PMID 17325195 DOI: 10.1085/jgp.200609677 |
0.476 |
|
2006 |
Egan TM, Samways DS, Li Z. Biophysics of P2X receptors. PflüGers Archiv : European Journal of Physiology. 452: 501-12. PMID 16708237 DOI: 10.1007/s00424-006-0078-1 |
0.49 |
|
2005 |
Khakh BS, Egan TM. Contribution of transmembrane regions to ATP-gated P2X2 channel permeability dynamics. The Journal of Biological Chemistry. 280: 6118-29. PMID 15556949 DOI: 10.1074/Jbc.M411324200 |
0.375 |
|
2004 |
Li Z, Migita K, Samways DS, Voigt MM, Egan TM. Gain and loss of channel function by alanine substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7378-86. PMID 15317863 DOI: 10.1523/Jneurosci.1423-04.2004 |
0.493 |
|
2004 |
Egan TM, Cox JA, Voigt MM. Molecular structure of P2X receptors. Current Topics in Medicinal Chemistry. 4: 821-9. PMID 15078213 DOI: 10.2174/1568026043451005 |
0.503 |
|
2004 |
Egan TM, Khakh BS. Contribution of calcium ions to P2X channel responses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3413-20. PMID 15056721 DOI: 10.1523/Jneurosci.5429-03.2004 |
0.385 |
|
2003 |
Kucenas S, Li Z, Cox JA, Egan TM, Voigt MM. Molecular characterization of the zebrafish P2X receptor subunit gene family. Neuroscience. 121: 935-45. PMID 14580944 DOI: 10.1016/S0306-4522(03)00566-9 |
0.414 |
|
2003 |
Egan TM, Migita K, Voigt MM. Relating the Structure of ATP-Gated Ion Channel Receptors to Their Function Current Topics in Membranes. 54: 183-202. DOI: 10.1016/S1063-5823(03)01006-8 |
0.516 |
|
2002 |
Diaz-Hernandez M, Cox JA, Migita K, Haines W, Egan TM, Voigt MM. Cloning and characterization of two novel zebrafish P2X receptor subunits. Biochemical and Biophysical Research Communications. 295: 849-53. PMID 12127972 DOI: 10.1016/S0006-291X(02)00760-X |
0.746 |
|
2001 |
Haines WR, Voigt MM, Migita K, Torres GE, Egan TM. On the contribution of the first transmembrane domain to whole-cell current through an ATP-gated ionotropic P2X receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5885-92. PMID 11487611 DOI: 10.1523/Jneurosci.21-16-05885.2001 |
0.777 |
|
2001 |
Haines WR, Migita K, Cox JA, Egan TM, Voigt MM. The first transmembrane domain of the P2X receptor subunit participates in the agonist-induced gating of the channel. The Journal of Biological Chemistry. 276: 32793-8. PMID 11438537 DOI: 10.1074/Jbc.M104216200 |
0.763 |
|
2001 |
Migita K, Haines WR, Voigt MM, Egan TM. Polar residues of the second transmembrane domain influence cation permeability of the ATP-gated P2X(2) receptor. The Journal of Biological Chemistry. 276: 30934-41. PMID 11402044 DOI: 10.1074/Jbc.M103366200 |
0.743 |
|
2000 |
Egan TM, Cox JA, Voigt MM. Molecular cloning and functional characterization of the zebrafish ATP-gated ionotropic receptor P2X(3) subunit. Febs Letters. 475: 287-90. PMID 10869573 DOI: 10.1016/S0014-5793(00)01685-9 |
0.553 |
|
1999 |
Haines WR, Torres GE, Voigt MM, Egan TM. Properties of the novel ATP-gated ionotropic receptor composed of the P2X(1) and P2X(5) isoforms. Molecular Pharmacology. 56: 720-7. PMID 10496954 |
0.763 |
|
1999 |
Torres GE, Egan TM, Voigt MM. Identification of a domain involved in ATP-gated ionotropic receptor subunit assembly. The Journal of Biological Chemistry. 274: 22359-65. PMID 10428806 DOI: 10.1074/Jbc.274.32.22359 |
0.546 |
|
1999 |
Torres GE, Egan TM, Voigt MM. Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners. The Journal of Biological Chemistry. 274: 6653-9. PMID 10037762 DOI: 10.1074/Jbc.274.10.6653 |
0.523 |
|
1998 |
Torres GE, Haines WR, Egan TM, Voigt MM. Co-expression of P2X1 and P2X5 receptor subunits reveals a novel ATP-gated ion channel. Molecular Pharmacology. 54: 989-93. PMID 9855626 DOI: 10.1124/Mol.54.6.989 |
0.757 |
|
1998 |
McCullough LA, Egan TM, Westfall TC. Neuropeptide Y receptors involved in calcium channel regulation in PC12 cells. Regulatory Peptides. 75: 101-7. PMID 9802399 DOI: 10.1016/S0167-0115(98)00058-5 |
0.408 |
|
1998 |
Torres GE, Egan TM, Voigt MM. N-Linked glycosylation is essential for the functional expression of the recombinant P2X2 receptor. Biochemistry. 37: 14845-51. PMID 9778359 DOI: 10.1021/Bi981209G |
0.498 |
|
1998 |
Torres GE, Egan TM, Voigt MM. Topological analysis of the ATP-gated ionotropic [correction of ionotrophic] P2X2 receptor subunit. Febs Letters. 425: 19-23. PMID 9540999 DOI: 10.1016/S0014-5793(98)00179-3 |
0.533 |
|
1998 |
Egan TM, Haines WR, Voigt MM. A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2350-9. PMID 9502796 DOI: 10.1523/Jneurosci.18-07-02350.1998 |
0.755 |
|
1998 |
Torres GE, Egan TM, Voigt MM. Erratum to: Topological analysis of the ATP-gated ionotropic P2X2
receptor subunit (FEBS 19946) Febs Letters. 427: 152-152. DOI: 10.1016/S0014-5793(98)00332-9 |
0.569 |
|
1993 |
Egan TM, Dagan D, Levitan IB. Properties and modulation of a calcium-activated potassium channel in rat olfactory bulb neurons. Journal of Neurophysiology. 69: 1433-42. PMID 8389824 DOI: 10.1152/jn.1993.69.5.1433 |
0.363 |
|
1992 |
Egan TM, Dagan D, Kupper J, Levitan IB. Na(+)-activated K+ channels are widely distributed in rat CNS and in Xenopus oocytes. Brain Research. 584: 319-21. PMID 1515948 DOI: 10.1016/0006-8993(92)90913-T |
0.305 |
|
1989 |
Egan TM. Single cell studies of the actions of agonists and antagonists on nicotinic receptors of the central nervous system Progress in Brain Research. 79: 73-83. PMID 2573913 DOI: 10.1016/S0079-6123(08)62466-8 |
0.35 |
|
1981 |
Egan T, North R. Both mu and delta opiate receptors exist on the same neuron Science. 214: 923-924. PMID 6272393 DOI: 10.1126/Science.6272393 |
0.455 |
|
Low-probability matches (unlikely to be authored by this person) |
2018 |
Janks L, Subitioni Antonio L, Coppens JR, Egan TM. Dynamic Regulation of P2X7 Receptors in Human Microglia by Bacterial Phagocytosis Biophysical Journal. 114: 156a. DOI: 10.1016/j.bpj.2017.11.876 |
0.273 |
|
2011 |
Samways DS, Egan TM. Calcium-dependent decrease in the single-channel conductance of TRPV1. PflüGers Archiv : European Journal of Physiology. 462: 681-91. PMID 21892726 DOI: 10.1007/s00424-011-1013-7 |
0.272 |
|
2017 |
Han J, Liu H, Liu C, Jin H, Perlmutter JS, Egan TM, Tu Z. Pharmacologic characterizations of a P2X7 receptor-specific radioligand, [11C]GSK1482160 for neuroinflammatory response. Nuclear Medicine Communications. PMID 28338530 DOI: 10.1097/Mnm.0000000000000660 |
0.271 |
|
2012 |
Barbacci D, Jackson SN, Muller L, Egan T, Lewis EK, Schultz JA, Woods AS. Cellular membrane phospholipids act as a depository for quaternary amine containing drugs thus competing with the acetylcholine/nicotinic receptor. Journal of Proteome Research. 11: 3382-9. PMID 22506649 DOI: 10.1021/Pr300184G |
0.271 |
|
2010 |
Sridharan M, Adderley SP, Bowles EA, Egan TM, Stephenson AH, Ellsworth ML, Sprague RS. Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1146-52. PMID 20622111 DOI: 10.1152/ajpheart.00301.2010 |
0.268 |
|
1998 |
Westfall TC, McCullough LA, Vickery L, Naes L, Yang CL, Han SP, Egan T, Chen X, MacArthur H. Effects of neuropeptide Y at sympathetic neuroeffector junctions. Advances in Pharmacology (San Diego, Calif.). 42: 106-10. PMID 9327858 DOI: 10.1016/S1054-3589(08)60707-3 |
0.267 |
|
2012 |
Egan TD, Obara S, Jenkins TE, Jaw-Tsai SS, Amagasu S, Cook DR, Steffensen SC, Beattie DT. AZD-3043: a novel, metabolically labile sedative-hypnotic agent with rapid and predictable emergence from hypnosis. Anesthesiology. 116: 1267-77. PMID 22531340 DOI: 10.1097/ALN.0b013e31825685a6 |
0.265 |
|
1998 |
McCullough LA, Egan TM, Westfall TC. Neuropeptide Y inhibition of calcium channels in PC-12 pheochromocytoma cells. American Journal of Physiology. Cell Physiology. 274: C1290-C1297. PMID 29591074 DOI: 10.1152/ajpcell.1998.274.5.C1290 |
0.223 |
|
2016 |
Li C, Ma W, Yin S, Liang X, Shu X, Pei D, Egan TM, Huang J, Pan A, Li Z. Sorting Nexin 11 Regulates Lysosomal Degradation of Plasma Membrane TRPV3. Traffic (Copenhagen, Denmark). PMID 26818531 DOI: 10.1111/Tra.12379 |
0.211 |
|
2010 |
Hicks A, Goodnow R, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Lora JM, Satjawatcharaphong J, Brovarney M, Dabbagh K, Tare NS, Oh H, Lamb M, Sidduri A, Dominique R, ... ... Egan T, et al. Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates. Prostaglandins & Other Lipid Mediators. 92: 33-43. PMID 20214997 DOI: 10.1016/J.Prostaglandins.2010.02.003 |
0.201 |
|
1992 |
Egan T, Dagan D, Kupper J, Levitan I. Properties and rundown of sodium-activated potassium channels in rat olfactory bulb neurons The Journal of Neuroscience. 12: 1964-1976. DOI: 10.1523/JNEUROSCI.12-05-01964.1992 |
0.199 |
|
2017 |
Sáez-Orellana F, Fuentes-Fuentes MC, Godoy PA, Silva-Grecchi T, Panes JD, Guzmán L, Yévenes G, Gavilán J, Egan TM, Aguayo LG, Fuentealba J. P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease. Neuropharmacology. PMID 29079292 DOI: 10.1016/j.neuropharm.2017.10.027 |
0.197 |
|
2007 |
Eifler N, Duckely M, Sumanovski LT, Egan TM, Oksche A, Konopka JB, Lüthi A, Engel A, Werten PJ. Functional expression of mammalian receptors and membrane channels in different cells. Journal of Structural Biology. 159: 179-93. PMID 17368047 DOI: 10.1016/J.Jsb.2007.01.014 |
0.194 |
|
2013 |
Ogura T, Egan TD. Opioid Agonists and Antagonists Pharmacology and Physiology For Anesthesia: Foundations and Clinical Application. 253-271. DOI: 10.1016/B978-1-4377-1679-5.00015-6 |
0.155 |
|
2015 |
Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Konnick Y, Tosh DK, Jacobson KA, Salvemini D. Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6057-67. PMID 25878279 DOI: 10.1523/Jneurosci.4495-14.2015 |
0.153 |
|
2009 |
Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages. European Journal of Immunology. 39: 820-5. PMID 19189309 DOI: 10.1002/Eji.200838683 |
0.134 |
|
2009 |
Zanotti G, Casiraghi M, Abano JB, Tatreau JR, Sevala M, Berlin H, Smyth S, Funkhouser WK, Burridge K, Randell SH, Egan TM. Novel critical role of Toll-like receptor 4 in lung ischemia-reperfusion injury and edema. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L52-63. PMID 19376887 DOI: 10.1152/Ajplung.90406.2008 |
0.122 |
|
2017 |
Ulmasov B, Bruno J, Oshima K, Cheng YW, Holly SP, Parise LV, Egan TM, Edwards JC. CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury. Physiological Reports. 5. PMID 28275112 DOI: 10.14814/Phy2.13169 |
0.111 |
|
2013 |
Joshi MC, Wicht KJ, Taylor D, Hunter R, Smith PJ, Egan TJ. In vitro antimalarial activity, β-haematin inhibition and structure-activity relationships in a series of quinoline triazoles. European Journal of Medicinal Chemistry. 69: 338-47. PMID 24077524 DOI: 10.1016/j.ejmech.2013.08.046 |
0.104 |
|
2022 |
Bruns J, Egan T, Mercier P, Zustiak SP. Glioblastoma spheroid growth and chemotherapeutic responses in single and dual-stiffness hydrogels. Acta Biomaterialia. PMID 35659918 DOI: 10.1016/j.actbio.2022.05.048 |
0.096 |
|
2012 |
Lin Z, Perez P, Sun Z, Liu JJ, Shin JH, Hyrc KL, Samways D, Egan T, Holley MC, Bao J. Reprogramming of single-cell-derived mesenchymal stem cells into hair cell-like cells Otology and Neurotology. 33: 1648-1655. PMID 23111404 DOI: 10.1097/Mao.0B013E3182713680 |
0.095 |
|
2011 |
Zishiri VK, Joshi MC, Hunter R, Chibale K, Smith PJ, Summers RL, Martin RE, Egan TJ. Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum chloroquine-resistance transporter (PfCRT). Journal of Medicinal Chemistry. 54: 6956-68. PMID 21875063 DOI: 10.1021/Jm2009698 |
0.095 |
|
2014 |
Raj R, Mehra V, Gut J, Rosenthal PJ, Wicht KJ, Egan TJ, Hopper M, Wrischnik LA, Land KM, Kumar V. Discovery of highly selective 7-chloroquinoline-thiohydantoins with potent antimalarial activity. European Journal of Medicinal Chemistry. 84: 425-32. PMID 25038484 DOI: 10.1016/j.ejmech.2014.07.048 |
0.091 |
|
2016 |
Wicht KJ, Combrinck JM, Smith PJ, Hunter R, Egan TJ. Identification and SAR evaluation of hemozoin-inhibiting benzamides active against Plasmodium falciparum. Journal of Medicinal Chemistry. PMID 27299916 DOI: 10.1021/acs.jmedchem.6b00719 |
0.089 |
|
2021 |
Tewari M, Khan M, Verma M, Coppens J, Kemp JM, Bucholz R, Mercier P, Egan TM. Physiology of Cultured Human Microglia Maintained in a Defined Culture Medium. Immunohorizons. 5: 257-272. PMID 33931497 DOI: 10.4049/immunohorizons.2000101 |
0.089 |
|
2016 |
Stringer T, De Kock C, Guzgay H, Okombo J, Liu J, Kanetake S, Kim J, Tam C, Cheng LW, Smith PJ, Hendricks DT, Land KM, Egan TJ, Smith GS. Mono- and multimeric ferrocene congeners of quinoline-based polyamines as potential antiparasitics. Dalton Transactions (Cambridge, England : 2003). PMID 27485032 DOI: 10.1039/c6dt02685k |
0.089 |
|
2011 |
Dubar F, Egan TJ, Pradines B, Kuter D, Ncokazi KK, Forge D, Paul JF, Pierrot C, Kalamou H, Khalife J, Buisine E, Rogier C, Vezin H, Forfar I, Slomianny C, et al. The antimalarial ferroquine: Role of the metal and intramolecular hydrogen bond in activity and resistance Acs Chemical Biology. 6: 275-287. PMID 21162558 DOI: 10.1021/Cb100322V |
0.088 |
|
2014 |
Shaban E, Wicht KJ, Wang N, Mei ZW, Hayashi I, El Gokha AAA, Kaiser M, El Sayed IET, Egan TJ, Inokuchi T. Synthesis and antimalarial activity of some neocryptolepine analogues carrying a multifunctional linear and branched carbon-side chains Heterocycles. 89: 1055-1064. DOI: 10.3987/COM-14-12948 |
0.088 |
|
2011 |
LaPierre CD, Johnson KB, Randall BR, White JL, Egan TD. An exploration of remifentanil-propofol combinations that lead to a loss of response to esophageal instrumentation, a loss of responsiveness, and/or onset of intolerable ventilatory depression. Anesthesia and Analgesia. 113: 490-9. PMID 21415430 DOI: 10.1213/ANE.0b013e318210fc45 |
0.087 |
|
2013 |
Lu WJ, Wicht KJ, Wang L, Imai K, Mei ZW, Kaiser M, El Sayed Iel T, Egan TJ, Inokuchi T. Synthesis and antimalarial testing of neocryptolepine analogues: addition of ester function in SAR study of 2,11-disubstituted indolo[2,3-b]quinolines. European Journal of Medicinal Chemistry. 64: 498-511. PMID 23685569 DOI: 10.1016/j.ejmech.2013.03.072 |
0.087 |
|
2013 |
Hanrahan SJ, Greger B, Parker RA, Ogura T, Obara S, Egan TD, House PA. The effects of propofol on local field potential spectra, action potential firing rate, and their temporal relationship in humans and felines. Frontiers in Human Neuroscience. 7: 136. PMID 23576977 DOI: 10.3389/Fnhum.2013.00136 |
0.086 |
|
2013 |
Combrinck JM, Mabotha TE, Ncokazi KK, Ambele MA, Taylor D, Smith PJ, Hoppe HC, Egan TJ. Insights into the role of heme in the mechanism of action of antimalarials Acs Chemical Biology. 8: 133-137. PMID 23043646 DOI: 10.1021/cb300454t |
0.083 |
|
2013 |
Andayi WA, Egan TJ, Gut J, Rosenthal PJ, Chibale K. Synthesis, Antiplasmodial Activity, and β-Hematin Inhibition of Hydroxypyridone-Chloroquine Hybrids. Acs Medicinal Chemistry Letters. 4: 642-6. PMID 24900724 DOI: 10.1021/Ml4001084 |
0.083 |
|
2008 |
Musonda CC, Yardley V, Carvalho De Souza RC, Ncokazi K, Egan TJ, Chibale K. Antiplasmodial, β-haematin inhibition, antitrypanosomal and cytotoxic activity in vitro of novel 4-aminoquinoline 2-imidazolines Organic and Biomolecular Chemistry. 6: 4446-4451. PMID 19005606 DOI: 10.1039/B813007H |
0.082 |
|
2008 |
Jackson SN, Ugarov M, Post JD, Egan T, Langlais D, Schultz JA, Woods AS. A study of phospholipids by ion mobility TOFMS. Journal of the American Society For Mass Spectrometry. 19: 1655-62. PMID 18703352 DOI: 10.1016/J.Jasms.2008.07.005 |
0.081 |
|
2013 |
Wang N, Wicht KJ, Wang L, Lu WJ, Misumi R, Wang MQ, El Gokha AA, Kaiser M, El Sayed Iel T, Egan TJ, Inokuchi T. Synthesis and in vitro testing of antimalarial activity of non-natural-type neocryptolepines: structure–activity relationship study of 2,11- and 9,11-disubstituted 6-methylindolo[2,3-b]quinolines. Chemical & Pharmaceutical Bulletin. 61: 1282-90. PMID 24436959 DOI: 10.1248/cpb.c13-00639 |
0.08 |
|
2014 |
Wang N, Wicht KJ, Imai K, Wang MQ, Anh Ngoc T, Kiguchi R, Kaiser M, Egan TJ, Inokuchi T. Synthesis, β-haematin inhibition, and in vitro antimalarial testing of isocryptolepine analogues: SAR study of indolo[3,2-c]quinolines with various substituents at C2, C6, and N11. Bioorganic & Medicinal Chemistry. 22: 2629-42. PMID 24721829 DOI: 10.1016/j.bmc.2014.03.030 |
0.079 |
|
2011 |
Zishiri VK, Hunter R, Smith PJ, Taylor D, Summers R, Kirk K, Martin RE, Egan TJ. A series of structurally simple chloroquine chemosensitizing dibemethin derivatives that inhibit chloroquine transport by PfCRT. European Journal of Medicinal Chemistry. 46: 1729-42. PMID 21396749 DOI: 10.1016/j.ejmech.2011.02.026 |
0.078 |
|
2014 |
Sandlin RD, Fong KY, Wicht KJ, Carrell HM, Egan TJ, Wright DW. Identification of β-hematin inhibitors in a high-throughput screening effort reveals scaffolds with in vitro antimalarial activity. International Journal For Parasitology. Drugs and Drug Resistance. 4: 316-25. PMID 25516843 DOI: 10.1016/J.Ijpddr.2014.08.002 |
0.074 |
|
2015 |
Sear JW, Egan TD. David (propofol wannabes) versus goliath (propofol): AZD-3043 goes up against the giant! Anesthesia and Analgesia. 121: 849-851. PMID 26378696 DOI: 10.1213/ANE.0000000000000904 |
0.072 |
|
2011 |
Jackson SN, Colsch B, Egan T, Lewis EK, Schultz JA, Woods AS. Gangliosides' analysis by MALDI-ion mobility MS. The Analyst. 136: 463-6. PMID 21113547 DOI: 10.1039/C0An00732C |
0.071 |
|
2009 |
Casiraghi M, Tatreau JR, Abano JB, Blackwell JW, Watson L, Burridge K, Randell SH, Egan TM. In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation. The Journal of Thoracic and Cardiovascular Surgery. 138: 760-7. PMID 19698867 DOI: 10.1016/J.Jtcvs.2009.05.037 |
0.071 |
|
2015 |
Egan TE, Jensvold MLA. Pretend play in signing chimpanzees (Pan troglogytes) Animal Communication and Cognition: Principles, Evolution and Development. 57-85. |
0.069 |
|
2015 |
Stringer T, Taylor D, Guzgay H, Shokar A, Au A, Smith PJ, Hendricks DT, Land KM, Egan TJ, Smith GS. Polyamine quinoline rhodium complexes: synthesis and pharmacological evaluation as antiparasitic agents against Plasmodium falciparum and Trichomonas vaginalis. Dalton Transactions (Cambridge, England : 2003). PMID 26226082 DOI: 10.1039/c5dt02378e |
0.068 |
|
2014 |
Egan T, O'Riordan D, O'Sullivan M, Jacquier JC. Cold-set whey protein microgels as pH modulated immobilisation matrices for charged bioactives Food Chemistry. 156: 197-203. PMID 24629958 DOI: 10.1016/j.foodchem.2014.01.109 |
0.067 |
|
2011 |
Feng TS, Guantai EM, Nell M, Van Rensburg CEJ, Ncokazi K, Egan TJ, Hoppe HC, Chibale K. Effects of highly active novel artemisinin-chloroquinoline hybrid compounds on β-hematin formation, parasite morphology and endocytosis in Plasmodium falciparum Biochemical Pharmacology. 82: 236-247. PMID 21596024 DOI: 10.1016/J.Bcp.2011.04.018 |
0.066 |
|
2013 |
Hemmings HC, Egan TD. Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application Pharmacology and Physiology For Anesthesia: Foundations and Clinical Application. 1-690. |
0.065 |
|
2013 |
Tian Z, Dong B, Blackwell JW, Stewart PW, Egan TM. Effect of a vascular endothelial cadherin antagonist in a rat lung transplant model. The Annals of Thoracic Surgery. 95: 1028-33. PMID 23333062 DOI: 10.1016/j.athoracsur.2012.11.023 |
0.065 |
|
2015 |
Ongarora DS, Strydom N, Wicht K, Njoroge M, Wiesner L, Egan TJ, Wittlin S, Jurva U, Masimirembwa CM, Chibale K. Antimalarial benzoheterocyclic 4-aminoquinolines: Structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies. Bioorganic & Medicinal Chemistry. 23: 5419-32. PMID 26264839 DOI: 10.1016/J.Bmc.2015.07.051 |
0.064 |
|
2014 |
Kim S, Egan TM, Moon MJ. Managerial Coaching Efficacy, Work-Related Attitudes, and Performance in Public Organizations: A Comparative International Study Review of Public Personnel Administration. 34: 237-262. DOI: 10.1177/0734371X13491120 |
0.063 |
|
2012 |
Ambele MA, Egan TJ. Neutral lipids associated with haemozoin mediate efficient and rapid -haematin formation at physiological pH, temperature and ionic composition Malaria Journal. 11. PMID 23043460 DOI: 10.1186/1475-2875-11-337 |
0.063 |
|
2012 |
LaPierre CD, Johnson KB, Randall BR, Egan TD. A simulation study of common propofol and propofol-opioid dosing regimens for upper endoscopy: implications on the time course of recovery. Anesthesiology. 117: 252-62. PMID 22728781 DOI: 10.1097/ALN.0b013e31825fb1b2 |
0.063 |
|
2014 |
Jackson SN, Barbacci D, Egan T, Lewis EK, Schultz JA, Woods AS. MALDI-Ion Mobility Mass Spectrometry of Lipids in Negative Ion Mode. Analytical Methods : Advancing Methods and Applications. 6: 5001-5007. PMID 24999374 DOI: 10.1039/C4Ay00320A |
0.063 |
|
2011 |
Guantai EM, Ncokazi K, Egan TJ, Gut J, Rosenthal PJ, Bhampidipati R, Kopinathan A, Smith PJ, Chibale K. Enone- and chalcone-chloroquinoline hybrid analogues: In silico guided design, synthesis, antiplasmodial activity, in vitro metabolism, and mechanistic studies Journal of Medicinal Chemistry. 54: 3637-3649. PMID 21500839 DOI: 10.1021/Jm200149E |
0.062 |
|
2008 |
de Villiers KA, Marques HM, Egan TJ. The crystal structure of halofantrine-ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials Journal of Inorganic Biochemistry. 102: 1660-1667. PMID 18508124 DOI: 10.1016/j.jinorgbio.2008.04.001 |
0.062 |
|
2014 |
Andayi WA, Egan TJ, Chibale K. Kojic acid derived hydroxypyridinone-chloroquine hybrids: Synthesis, crystal structure, antiplasmodial activity and β-haematin inhibition Bioorganic and Medicinal Chemistry Letters. 24: 3263-3267. PMID 24974345 DOI: 10.1016/J.Bmcl.2014.06.012 |
0.06 |
|
2014 |
Wang N, Wicht KJ, Shaban E, Ngoc TA, Wang MQ, Hayashi I, Hossain MI, Takemasa Y, Kaiser M, El Tantawy El Sayed I, Egan TJ, Inokuchi T. Synthesis and evaluation of artesunate-indoloquinoline hybrids as antimalarial drug candidates Medchemcomm. 5: 927-931. DOI: 10.1039/c4md00091a |
0.059 |
|
2013 |
Nsumiwa S, Kuter D, Wittlin S, Chibale K, Egan TJ. Structure-activity relationships for ferriprotoporphyrin IX association and β-hematin inhibition by 4-aminoquinolines using experimental and ab initio methods Bioorganic and Medicinal Chemistry. 21: 3738-3748. PMID 23669191 DOI: 10.1016/J.Bmc.2013.04.040 |
0.059 |
|
2009 |
Egan TD. Is anesthesiology going soft? Trends in fragile pharmacology Anesthesiology. 111: 229-230. PMID 19625797 DOI: 10.1097/ALN.0b013e3181ae8460 |
0.057 |
|
2008 |
October N, Watermeyer ND, Yardley V, Egan TJ, Ncokazi K, Chibale K. Reversed chloroquines based on the 3,4-dihydropyrimidin-2(1H)-one scaffold: Synthesis and evaluation for antimalarial, β-haematin inhibition, and cytotoxic activity Chemmedchem. 3: 1649-1653. PMID 18846586 DOI: 10.1002/Cmdc.200800172 |
0.057 |
|
2009 |
Asher C, De Villiers KA, Egan TJ. Speciation of ferriprotoporphyrin IX in aqueous and mixed aqueous solution Is controlled by solvent identity, pH, and salt concentration Inorganic Chemistry. 48: 7994-8003. PMID 19572726 DOI: 10.1021/ic900647y |
0.056 |
|
2014 |
Newman J, Egan T, Harbourne N, O'Riordan D, Jacquier JC, O'Sullivan M. Correlation of sensory bitterness in dairy protein hydrolysates: Comparison of prediction models built using sensory, chromatographic and electronic tongue data Talanta. 126: 46-53. PMID 24881533 DOI: 10.1016/j.talanta.2014.03.036 |
0.056 |
|
2010 |
Stiebler R, Hoang AN, Egan TJ, Wright DW, Oliveira MF. Increase on the initial soluble heme levels in acidic conditions is an important mechanism for spontaneous heme crystallization in vitro. Plos One. 5: e12694. PMID 20856937 DOI: 10.1371/Journal.Pone.0012694 |
0.056 |
|
2013 |
Gildenhuys J, Roex TL, Egan TJ, De Villiers KA. The single crystal X-ray structure of β-hematin DMSO solvate grown in the presence of chloroquine, a β-hematin growth-rate inhibitor Journal of the American Chemical Society. 135: 1037-1047. PMID 23253048 DOI: 10.1021/ja308741e |
0.053 |
|
2009 |
Dong BM, Abano JB, Egan TM. Nitric oxide ventilation of rat lungs from non-heart-beating donors improves posttransplant function American Journal of Transplantation. 9: 2707-2715. PMID 19845592 DOI: 10.1111/j.1600-6143.2009.02840.x |
0.053 |
|
2016 |
Bellairs J, Hlozek J, Egan T, Kuttel M. An eHealth android application for mobile analysis of microplate assays 2016 Ist-Africa Conference, Ist-Africa 2016. DOI: 10.1109/ISTAFRICA.2016.7530644 |
0.051 |
|
2010 |
Johnson KB, Syroid ND, Gupta DK, Manyam SC, Pace NL, LaPierre CD, Egan TD, White JL, Tyler D, Westenskow DR. An evaluation of remifentanil-sevoflurane response surface models in patients emerging from anesthesia: model improvement using effect-site sevoflurane concentrations. Anesthesia and Analgesia. 111: 387-94. PMID 19820241 DOI: 10.1213/Ane.0B013E3181Afe31C |
0.05 |
|
2009 |
Corrêa Soares JB, Menezes D, Vannier-Santos MA, Ferreira-Pereira A, Almeida GT, Venancio TM, Verjovski-Almeida S, Zishiri VK, Kuter D, Hunter R, Egan TJ, Oliveira MF. Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols. Plos Neglected Tropical Diseases. 3: e477. PMID 19597543 DOI: 10.1371/journal.pntd.0000477 |
0.048 |
|
2015 |
O'Neill GJ, Egan T, Jacquier JC, O'Sullivan M, Dolores O'Riordan E. Kinetics of immobilisation and release of tryptophan, riboflavin and peptides from whey protein microbeads Food Chemistry. 180: 150-155. PMID 25766812 DOI: 10.1016/j.foodchem.2015.01.131 |
0.048 |
|
2013 |
Rawoens G, Egan T. Distinguishing causative and permissive readings of the Swedish verb låta Functions of Language. 20: 64-89. DOI: 10.1075/fol.20.1.03raw |
0.048 |
|
2014 |
Kuter D, Streltsov V, Davydova N, Venter GA, Naidoo KJ, Egan TJ. Molecular structures and solvation of free monomeric and dimeric ferriheme in aqueous solution: Insights from molecular dynamics simulations and extended X-ray absorption fine structure spectroscopy Inorganic Chemistry. 53: 10811-10824. PMID 25275882 DOI: 10.1021/ic500454d |
0.048 |
|
2015 |
Chugh M, Scheurer C, Sax S, Bilsland E, van Schalkwyk DA, Wicht KJ, Hofmann N, Sharma A, Bashyam S, Singh S, Oliver SG, Egan TJ, Malhotra P, Sutherland CJ, Beck HP, et al. Identification and deconvolution of cross-resistance signals from antimalarial compounds using multidrug-resistant Plasmodium falciparum strains. Antimicrobial Agents and Chemotherapy. 59: 1110-8. PMID 25487796 DOI: 10.1128/Aac.03265-14 |
0.047 |
|
2010 |
Syroid ND, Johnson KB, Pace NL, Westenskow DR, Tyler D, Brühschwein F, Albert RW, Roalstad S, Costy-Bennett S, Egan TD. Response surface model predictions of emergence and response to pain in the recovery room: An evaluation of patients emerging from an isoflurane and fentanyl anesthetic. Anesthesia and Analgesia. 111: 380-6. PMID 19820239 DOI: 10.1213/ane.0b013e3181b11289 |
0.047 |
|
2012 |
Talisuna AO, Daumerie PG, Balyeku A, Egan T, Piot B, Coghlan R, Lugand M, Bwire G, Rwakimari JB, Ndyomugyenyi R, Kato F, Byangire M, Kagwa P, Sebisubi F, Nahamya D, et al. Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study. Malaria Journal. 11: 356. PMID 23107021 DOI: 10.1186/1475-2875-11-356 |
0.046 |
|
2013 |
Egan T. First step toward: Destiny American History. 48: 38-39. |
0.046 |
|
2010 |
Stiebler R, Timm BL, Oliveira PL, Hearne GR, Egan TJ, Oliveira MF. On the physico-chemical and physiological requirements of hemozoin formation promoted by perimicrovillar membranes in Rhodnius prolixus midgut Insect Biochemistry and Molecular Biology. 40: 284-292. PMID 20060043 DOI: 10.1016/j.ibmb.2009.12.013 |
0.046 |
|
2016 |
Kuter D, Mohunlal R, Fitzroy SM, Asher C, Smith PJ, Egan TJ, De Villiers KA. Insights into the initial stages of lipid-mediated haemozoin nucleation Crystengcomm. 18: 5177-5187. DOI: 10.1039/c6ce00866f |
0.044 |
|
2010 |
Hoang AN, Ncokazi KK, de Villiers KA, Wright DW, Egan TJ. Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles. Dalton Transactions (Cambridge, England : 2003). 39: 1235-44. PMID 20104349 DOI: 10.1039/B914359A |
0.044 |
|
2013 |
Egan TJ, Kuter D. Dual-functioning antimalarials that inhibit the chloroquine-resistance transporter Future Microbiology. 8: 475-489. PMID 23534360 DOI: 10.2217/fmb.13.18 |
0.044 |
|
2011 |
Hayes JM, Anderson LC, Schultz JA, Ugarov M, Egan TF, Lewis EK, Womack V, Woods AS, Jackson SN, Hauge RH, Kittrell C, Ripley S, Murray KK. Matrix assisted laser desorption ionization ion mobility time-of-flight mass spectrometry of bacteria Acs Symposium Series. 1065: 143-160. DOI: 10.1021/bk-2011-1065.ch009 |
0.043 |
|
2014 |
Stiebler R, Majerowicz D, Knudsen J, Gondim KC, Wright DW, Egan TJ, Oliveira MF. Unsaturated glycerophospholipids mediate heme crystallization: biological implications for hemozoin formation in the kissing bug Rhodnius prolixus. Plos One. 9: e88976. PMID 24586467 DOI: 10.1371/Journal.Pone.0088976 |
0.043 |
|
2011 |
Kuter D, Chibale K, Egan TJ. Linear free energy relationships predict coordination and π-stacking interactions of small molecules with ferriprotoporphyrin IX Journal of Inorganic Biochemistry. 105: 684-692. PMID 21450272 DOI: 10.1016/J.Jinorgbio.2011.02.008 |
0.043 |
|
2010 |
Cho Dr. Y, Egan TM. The state of the art of action learning research Advances in Developing Human Resources. 12: 163-180. DOI: 10.1177/1523422310367881 |
0.042 |
|
2015 |
Combrinck JM, Fong KY, Gibhard L, Smith PJ, Wright DW, Egan TJ. Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials. Malaria Journal. 14: 253. PMID 26099266 DOI: 10.1186/S12936-015-0729-9 |
0.042 |
|
2010 |
Guantai EM, Ncokazi K, Egan TJ, Gut J, Rosenthal PJ, Smith PJ, Chibale K. Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds Bioorganic and Medicinal Chemistry. 18: 8243-8256. PMID 21044845 DOI: 10.1016/J.Bmc.2010.10.009 |
0.041 |
|
2012 |
Egan T. Through seen through the looking glass of translation equivalence: A proposed method for determining closeness of word senses Language and Computers. 74: 41-56. |
0.04 |
|
2013 |
Egan T, Jacquier JC, Rosenberg Y, Rosenberg M. Cold-set whey protein microgels for the stable immobilization of lipids Food Hydrocolloids. 31: 317-324. DOI: 10.1016/j.foodhyd.2012.11.008 |
0.039 |
|
2009 |
Sakata DJ, Matsubara I, Gopalakrishnan NA, Westenskow DR, White JL, Yamamori S, Egan TD, Pace NL. Flow-through versus sidestream capnometry for detection of end tidal carbon dioxide in the sedated patient. Journal of Clinical Monitoring and Computing. 23: 115-22. PMID 19301133 DOI: 10.1007/s10877-009-9171-2 |
0.039 |
|
2009 |
De Villiers KA, Egan TJ. Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis Molecules. 14: 2868-2887. PMID 19701131 DOI: 10.3390/molecules14082868 |
0.039 |
|
2014 |
O'Neill GJ, Egan T, Jacquier JC, O'Sullivan M, Dolores O'Riordan E. Whey microbeads as a matrix for the encapsulation and immobilisation of riboflavin and peptides Food Chemistry. 160: 46-52. PMID 24799207 DOI: 10.1016/j.foodchem.2014.03.002 |
0.038 |
|
2016 |
Kuter D, Streltsov V, Davydova N, Venter GA, Naidoo KJ, Egan TJ. Solution structures of chloroquine-ferriheme complexes modeled using MD simulation and investigated by EXAFS spectroscopy Journal of Inorganic Biochemistry. 154: 114-125. DOI: 10.1016/j.jinorgbio.2015.06.010 |
0.038 |
|
2013 |
Kim S, Egan TM, Kim W, Kim J. The Impact of Managerial Coaching Behavior on Employee Work-Related Reactions Journal of Business and Psychology. 28: 315-330. DOI: 10.1007/s10869-013-9286-9 |
0.038 |
|
2014 |
Egan T, Jacquier JC, Rosenberg Y, Rosenberg M. Cold-set whey protein microgels containing immobilised lipid phases to modulate matrix digestion and release of a water-soluble bioactive Journal of Microencapsulation. 31: 184-192. PMID 23937209 DOI: 10.3109/02652048.2013.824513 |
0.037 |
|
2015 |
O'Neill GJ, Jacquier JC, Mukhopadhya A, Egan T, O'Sullivan M, Sweeney T, O'Riordan ED. In vitro and in vivo evaluation of whey protein hydrogels for oral delivery of riboflavin Journal of Functional Foods. 19: 512-521. DOI: 10.1016/J.Jff.2015.09.043 |
0.037 |
|
2014 |
Verlinden BK, de Beer M, Pachaiyappan B, Besaans E, Andayi WA, Reader J, Niemand J, van Biljon R, Guy K, Egan T, Woster PM, Birkholtz LM. Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites Bioorganic and Medicinal Chemistry. DOI: 10.1016/j.bmc.2015.01.036 |
0.037 |
|
2010 |
Macedo B, Kaschula CH, Hunter R, Chaves JA, van der Merwe JD, Silva JL, Egan TJ, Cordeiro Y. Synthesis and anti-prion activity evaluation of aminoquinoline analogues. European Journal of Medicinal Chemistry. 45: 5468-73. PMID 20797807 DOI: 10.1016/J.Ejmech.2010.07.054 |
0.037 |
|
2015 |
Villani AM, Egan T, Keogh JB, Clifton PM. Attitudes and beliefs of australian adults on reality television cooking programmes and celebrity chefs. Is there cause for concern? Descriptive analysis presented from a consumer survey Appetite. 91: 7-12. DOI: 10.1016/j.appet.2015.03.021 |
0.036 |
|
2013 |
Stringer T, Taylor D, de Kock C, Guzgay H, Au A, An SH, Sanchez B, O'Connor R, Patel N, Land KM, Smith PJ, Hendricks DT, Egan TJ, Smith GS. Synthesis, characterization, antiparasitic and cytotoxic evaluation of thioureas conjugated to polyamine scaffolds. European Journal of Medicinal Chemistry. 69: 90-8. PMID 24012713 DOI: 10.1016/j.ejmech.2013.08.004 |
0.036 |
|
2013 |
Nosrati K, Zare S, Egan TP. BREAKING SEED DORMANCY IN THE WHITE SAXAUL TREE (HALOXYLON PERSICUM BOISS. ET BUHSE) AMARANTHACEAE Journal of Plant Nutrition. 36: 1821-1828. DOI: 10.1080/01904167.2013.815203 |
0.035 |
|
2015 |
Egan T, Graedler AL. Motion into and out of in English, French and Norwegian Njes Nordic Journal of English Studies. 14: 9-33. |
0.035 |
|
2014 |
Egan T, Hamlin RG. Coaching, HRD, and Relational Richness: Putting the Pieces Together Advances in Developing Human Resources. 16: 242-257. DOI: 10.1177/1523422313520475 |
0.035 |
|
2015 |
Stringer T, Guzgay H, Combrinck JM, Hopper M, Hendricks DT, Smith PJ, Land KM, Egan TJ, Smith GS. Synthesis, characterization and pharmacological evaluation of ferrocenyl azines and their rhodium(I) complexes Journal of Organometallic Chemistry. 788: 1-8. DOI: 10.1016/j.jorganchem.2015.04.009 |
0.035 |
|
2015 |
Dambuza NS, Smith P, Evans A, Norman J, Taylor D, Andayi A, Egan T, Chibale K, Wiesner L. Antiplasmodial activity, in vivo pharmacokinetics and anti-malarial efficacy evaluation of hydroxypyridinone hybrids in a mouse model. Malaria Journal. 14: 505. PMID 26671222 DOI: 10.1186/S12936-015-1032-5 |
0.034 |
|
2013 |
Yu L, Ting CK, Hill BE, Orr JA, Brewer LM, Johnson KB, Egan TD, Westenskow DR. Using the entropy of tracheal sounds to detect apnea during sedation in healthy nonobese volunteers. Anesthesiology. 118: 1341-9. PMID 23407106 DOI: 10.1097/Aln.0B013E318289Bb30 |
0.034 |
|
2015 |
Kim TK, Niklewski PJ, Martin JF, Obara S, Egan TD. Enhancing a sedation score to include truly noxious stimulation: the Extended Observer's Assessment of Alertness and Sedation (EOAA/S). British Journal of Anaesthesia. 115: 569-77. PMID 26385665 DOI: 10.1093/bja/aev306 |
0.033 |
|
2013 |
Dong B, Stewart PW, Egan TM. Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors. The Journal of Thoracic and Cardiovascular Surgery. 146: 429-36.e1. PMID 23260460 DOI: 10.1016/j.jtcvs.2012.11.005 |
0.033 |
|
2009 |
Cho Y, Egan TM. Action learning research: A systematic review and conceptual framework Human Resource Development Review. 8: 431-462. DOI: 10.1177/1534484309345656 |
0.032 |
|
2014 |
Egan T, Rawoens G. English amid(st) and among(st): A contrastive approach based on Norwegian and Swedish translation Language and Computers. 78: 207-228. |
0.032 |
|
2015 |
Corbett Y, Parapini S, D'Alessandro S, Scaccabarozzi D, Rocha BC, Egan TJ, Omar A, Galastri L, Fitzgerald KA, Golenbock DT, Taramelli D, Basilico N. Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin. Microbes and Infection / Institut Pasteur. 17: 184-94. PMID 25462568 DOI: 10.1016/j.micinf.2014.11.001 |
0.032 |
|
2014 |
Egan T, Rodriguez-Pascual M, Lewis A. In situ growth measurements of sodium sulfate during cooling crystallization Chemical Engineering and Technology. 37: 1283-1290. DOI: 10.1002/ceat.201400098 |
0.031 |
|
2014 |
Kuter D, Benjamin SJ, Egan TJ. Multiple spectroscopic and magnetic techniques show that chloroquine induces formation of the μ-oxo dimer of ferriprotoporphyrin IX Journal of Inorganic Biochemistry. 133: 40-49. PMID 24480793 DOI: 10.1016/j.jinorgbio.2014.01.002 |
0.03 |
|
2010 |
Upton MG, Egan TM. Three approaches to multilevel theory building Human Resource Development Review. 9: 333-356. DOI: 10.1177/1534484310380333 |
0.03 |
|
2011 |
Kim S, Egan T. Establishing a formal cross-cultural mentoring organization and program: A case study of International Student Mentor Association in a higher education context Journal of European Industrial Training. 35: 89-105. DOI: 10.1108/03090591111095754 |
0.03 |
|
2015 |
Wicht KJ, Combrinck JM, Smith PJ, Egan TJ. Bayesian models trained with HTS data for predicting β-haematin inhibition and in vitro antimalarial activity Bioorganic and Medicinal Chemistry. 23: 5210-5217. DOI: 10.1016/j.bmc.2014.12.020 |
0.03 |
|
2015 |
Burker EJ, Fingerhut D, Ebneter D, Giza M, Espey Weber R, Noone PG, Egan TM. Emergency medical services knowledge and attitudes about non-heart-beating donors: effect of an educational intervention. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 34: 204-12. PMID 25447576 DOI: 10.1016/j.healun.2014.09.020 |
0.03 |
|
2009 |
De Villiers KA, Osipova M, Mabotha TE, Solomonov I, Feldman Y, Kjaer K, Weissbuch I, Egan TJ, Leiserowitz L. Oriented nucleation of β-hematin crystals induced at various interfaces: Relevance to hemozoin formation Crystal Growth and Design. 9: 626-632. DOI: 10.1021/cg8009755 |
0.029 |
|
2012 |
Syroid N, Liu D, Albert R, Agutter J, Egan TD, Pace NL, Johnson KB, Dowdle MR, Pulsipher D, Westenskow DR. Graphical user interface simplifies infusion pump programming and enhances the ability to detect pump-related faults. Anesthesia and Analgesia. 115: 1087-97. PMID 23011557 DOI: 10.1213/ANE.0b013e31826b46bc |
0.028 |
|
2012 |
Kuter D, Venter GA, Naidoo KJ, Egan TJ. Experimental and time-dependent density functional theory characterization of the UV-visible spectra of monomeric and μ-oxo dimeric ferriprotoporphyrin IX Inorganic Chemistry. 51: 10233-10250. PMID 22963249 DOI: 10.1021/ic301154e |
0.028 |
|
2013 |
Kim S, Egan T. Invited Reaction: The Contrasting Effects of Coaching Style on Task Performance: The Mediating Roles of Subjective Task Complexity and Self-Set Goal Human Resource Development Quarterly. 24: 459-468. DOI: 10.1002/hrdq.21177 |
0.028 |
|
2011 |
Wilkinson TJ, Tweed MJ, Egan TG, Ali AN, McKenzie JM, Moore M, Rudland JR. Joining the dots: Conditional pass and programmatic assessment enhances recognition of problems with professionalism and factors hampering student progress Bmc Medical Education. 11. PMID 21649925 DOI: 10.1186/1472-6920-11-29 |
0.027 |
|
2013 |
Obara S, Egan TD. Pharmacokinetic and Pharmacodynamic Principles for Intravenous Anesthetics Pharmacology and Physiology For Anesthesia: Foundations and Clinical Application. 20-42. DOI: 10.1016/B978-1-4377-1679-5.00002-8 |
0.027 |
|
2010 |
Bijanzadeh E, Nosrati K, Egan T. Influence of seed priming techniques on germination and emergence of rapeseed (Brassica napus L.) Seed Science and Technology. 38: 242-247. |
0.027 |
|
2010 |
Hoang AN, Ncokazi KK, De Villiers KA, Wright DW, Egan TJ. Crystallization of synthetic hemozoin (beta-hematin) nucleated at the surface of synthetic neutral lipid bodies Materials Research Society Symposium Proceedings. 1274: 51-56. DOI: 10.1557/Proc-1274-Qq05-13 |
0.027 |
|
2016 |
Egan T. Contrasting translations Njes Nordic Journal of English Studies. 15: 80-101. |
0.026 |
|
2008 |
Shahbazi A, Nosrati K, Egan TP. Influence of temperature and salinity on the germination and early seedling growth of Atriplex lentiformis and Atriplex verrucifera Seed Science and Technology. 36: 339-349. |
0.026 |
|
2009 |
Poynton L, Dowell A, Dew K, Egan T. GPs commonly refer patients for complementary and alternative medicine (CAM) therapies Journal of Primary Health Care. 1: 164. |
0.026 |
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2015 |
Johnson K, Egan TD. Blood loss: Does it change my intravenous anesthetic? Trauma Anesthesia, Second Edition. 105-112. DOI: 10.1017/CBO9781139814713.012 |
0.025 |
|
2013 |
Akdere M, Egan T. Examining higher education-community partnerships through human resource development: Implications for innovation and technology management International Journal of Innovation and Technology Management. 10. DOI: 10.1142/S0219877013500089 |
0.025 |
|
2010 |
Hoang AN, Sandlin RD, Omar A, Egan TJ, Wright DW. The neutral lipid composition present in the digestive vacuole of Plasmodium falciparum concentrates heme and mediates β-hematin formation with an unusually low activation energy. Biochemistry. 49: 10107-16. PMID 20979358 DOI: 10.1021/Bi101397U |
0.025 |
|
2013 |
Cho Y, Egan T. Organizational Support for Action Learning in South Korean Organizations Human Resource Development Quarterly. 24: 185-213. DOI: 10.1002/hrdq.21154 |
0.025 |
|
2012 |
Lahl S, Egan TD. Bridging the complexity gap: Leading effectively in a VUCA World Graziadio Business Report. 15. |
0.025 |
|
2015 |
Kim J, Egan T, Tolson H. Examining the Dimensions of the Learning Organization Questionnaire: A Review and Critique of Research Utilizing the DLOQ Human Resource Development Review. 14: 91-112. DOI: 10.1177/1534484314555402 |
0.024 |
|
2011 |
Roe-Sepowitz DE, Hickle KE, Loubert MP, Egan T. Adult prostitution recidivism: Risk factors and impact of a diversion program Journal of Offender Rehabilitation. 50: 272-285. DOI: 10.1080/10509674.2011.574205 |
0.024 |
|
2016 |
Naderi R, Bijanzadeh E, Nosrati K, Egan TP. The effect of composted municipal waste, sheep manure, and urea nitrogen on the growth and chemical composition of two rapeseed cultivars Journal of Plant Nutrition. 39: 1328-1335. DOI: 10.1080/01904167.2015.1043382 |
0.022 |
|
2008 |
Egan TM. The relevance of organizational subculture for motivation to transfer learning Human Resource Development Quarterly. 19: 299-322. DOI: 10.1002/hrdq.1243 |
0.022 |
|
2015 |
Egan TM, Requard JJ. Uncontrolled Donation after Circulatory Determination of Death Donors (uDCDDs) as a Source of Lungs for Transplant American Journal of Transplantation. 15: 2031-2036. DOI: 10.1111/ajt.13246 |
0.021 |
|
2011 |
Wallentine CB, Shimode N, Egan TD, Pace NL. Propofol in a modified cyclodextrin formulation: First human study of dose-response with emphasis on injection pain Anesthesia and Analgesia. 113: 738-741. PMID 21890884 DOI: 10.1213/ANE.0b013e31822b8648 |
0.021 |
|
2013 |
Alagaraja M, Egan T. The strategic value of HRD in lean strategy implementation Human Resource Development Quarterly. 24: 1-27. DOI: 10.1002/Hrdq.21155 |
0.02 |
|
2015 |
Young JE, Williamson MI, Egan TG. Students' reflections on the relationships between safe learning environments, learning challenge and positive experiences of learning in a simulated GP clinic. Advances in Health Sciences Education : Theory and Practice. PMID 25952645 DOI: 10.1007/s10459-015-9611-3 |
0.02 |
|
2013 |
Egan T, Rawoens G. Moving over in(to) English and French: A translation-based study of 'overness' Languages in Contrast. 13: 193-211. DOI: 10.1075/lic.13.2.04ega |
0.02 |
|
2011 |
Macleod R, Egan T. Interprofessional Education Education in Palliative Care: Building a Culture of Learning. DOI: 10.1093/acprof:oso/9780198569855.003.0022 |
0.019 |
|
2015 |
Figueiras M, Coelho L, Wicht KJ, Santos SA, Lavrado J, Gut J, Rosenthal PJ, Nogueira F, Egan TJ, Moreira R, Paulo A. N10,N11-di-alkylamine indolo[3,2-b]quinolines as hemozoin inhibitors: design, synthesis and antiplasmodial activity. Bioorganic & Medicinal Chemistry. 23: 1530-9. PMID 25725608 DOI: 10.1016/j.bmc.2015.02.007 |
0.018 |
|
2014 |
Egan TM. A little bit of leak goes a long way Journal of Heart and Lung Transplantation. 33: 769. PMID 24815796 DOI: 10.1016/j.healun.2014.04.008 |
0.015 |
|
2016 |
Dark JH, Egan TM. Lungs from the Controlled Donation after Circulatory Determination of Death Donor: Perspectives from the United States and beyond American Journal of Transplantation. 16: 1047-1048. DOI: 10.1111/ajt.13600 |
0.015 |
|
2009 |
Egan T, Jaye C. Communities of clinical practice: The social organization of clinical learning Health. 13: 107-125. PMID 19103718 DOI: 10.1177/1363459308097363 |
0.015 |
|
2013 |
Egan T. Response to Nieminen et al.'s Feature Article on Executive Coaching and Facilitated Multisource Feedback: Toward Better Understanding of a Growing HRD Practice Human Resource Development Quarterly. 24: 177-183. DOI: 10.1002/hrdq.21159 |
0.014 |
|
2009 |
Jaye C, Egan T, Smith-Han K, Thompson-Fawcett M. Teaching and learning in the hospital ward New Zealand Medical Journal. 122: 13-22. PMID 19859088 |
0.014 |
|
2013 |
Williamson M, Walker T, Egan T, Storr E, Ross J, Kenrick K. The Safe and Effective Clinical Outcomes (SECO) clinic: learning responsibility for patient care through simulation. Teaching and Learning in Medicine. 25: 155-8. PMID 23530678 DOI: 10.1080/10401334.2013.772016 |
0.013 |
|
2010 |
Jaye C, Egan T, Smith-Han K. Communities of clinical practice and normalising technologies of self: Learning to fit in on the surgical ward Anthropology and Medicine. 17: 59-73. PMID 20419517 DOI: 10.1080/13648470903569388 |
0.012 |
|
2014 |
Egan T. Encoding 'throughness' in English and French Linguistic Insights. 181: 233-257. |
0.012 |
|
2013 |
Ambele MA, Sewell BT, Cummings FR, Smith PJ, Egan TJ. Synthetic Hemozoin (β-Hematin) Crystals Nucleate at the Surface of Neutral Lipid Droplets that Control Their Sizes. Crystal Growth & Design. 13. PMID 24244110 DOI: 10.1021/cg4009416 |
0.012 |
|
2014 |
Beattie RS, Kim S, Hagen MS, Egan TM, Ellinger AD, Hamlin RG. Managerial Coaching: A Review of the Empirical Literature and Development of a Model to Guide Future Practice Advances in Developing Human Resources. 16: 184-201. DOI: 10.1177/1523422313520476 |
0.011 |
|
2016 |
Egan TM, Edwards LB. Effect of the lung allocation score on lung transplantation in the United States. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. PMID 26922274 DOI: 10.1016/j.healun.2016.01.010 |
0.01 |
|
2016 |
Shafer SL, Egan T. Target-Controlled Infusions: Surfing USA Redux Anesthesia and Analgesia. 122: 1-3. DOI: 10.1213/ANE.0000000000001061 |
0.01 |
|
2016 |
Egan TM. Lung Transplant from an Uncontrolled Donation after Circulatory Determination of Death Donor: Moving to Other Countries American Journal of Transplantation. 16: 1051-1052. DOI: 10.1111/ajt.13658 |
0.01 |
|
2015 |
Egan TJ. Drug-resistant Plasmodium falciparum: Are recent advances a cause for optimism? Future Microbiology. 10: 1261-1263. PMID 26226625 DOI: 10.2217/FMB.15.58 |
0.01 |
|
2015 |
Younes M, Thompson W, Leslie C, Egan T, Giannouli E. Utility of Technologist Editing of Polysomnography Scoring Performed by a Validated Automatic System. Annals of the American Thoracic Society. PMID 26065574 DOI: 10.1513/AnnalsATS.201411-512OC |
0.01 |
|
2015 |
Egan TD. Update on Total Intravenous Anesthesia With Special Emphasis on Cardiovascular Anesthesia Journal of Cardiothoracic and Vascular Anesthesia. 29: S1-S2. DOI: 10.1053/j.jvca.2015.01.025 |
0.01 |
|
2015 |
Egan TD. Total Intravenous Anesthesia Versus Inhalation Anesthesia: A Drug Delivery Perspective Journal of Cardiothoracic and Vascular Anesthesia. 29: S3-S6. DOI: 10.1053/j.jvca.2015.01.024 |
0.01 |
|
2014 |
Evans SW, Langberg JM, Egan T, Molitor SJ. Middle School-based and High School-based Interventions for Adolescents with ADHD Child and Adolescent Psychiatric Clinics of North America. 23: 699-715. PMID 25220081 DOI: 10.1016/j.chc.2014.05.004 |
0.01 |
|
2014 |
Egan TM. The lung allocation score goes global American Journal of Transplantation. 14: 1234-1235. PMID 24854158 DOI: 10.1111/ajt.12754 |
0.01 |
|
2014 |
Egan T. Organization development in the context of HRD: From diagnostic to dialogic perspectives The Routledge Companion to Human Resource Development. 53-66. |
0.01 |
|
2013 |
Egan TM, Sweet SC. Rationing lung transplants. The New England Journal of Medicine. 369: 2064-5. PMID 24256395 DOI: 10.1056/Nejmc1311946 |
0.01 |
|
2013 |
Michael KD, Albright A, Jameson JP, Sale R, Massey C, Kirk A, Egan T. Does cognitive behavioural therapy in the context of a rural school mental health programme have an impact on academic outcomes? Advances in School Mental Health Promotion. 6: 247-262. DOI: 10.1080/1754730X.2013.832006 |
0.01 |
|
2013 |
Albright A, Michael K, Massey C, Sale R, Kirk A, Egan T. An evaluation of an interdisciplinary rural school mental health programme in appalachia Advances in School Mental Health Promotion. 6: 189-202. DOI: 10.1080/1754730X.2013.808890 |
0.01 |
|
2013 |
Hemmings HC, Egan TD. Preface Pharmacology and Physiology For Anesthesia: Foundations and Clinical Application. vii. DOI: 10.1016/B978-1-4377-1679-5.00040-5 |
0.01 |
|
2013 |
Egan T. The impact of leader coaching behavior on engineers' motivation to learn and voicing behavior Asee Annual Conference and Exposition, Conference Proceedings. |
0.01 |
|
2012 |
Fenn P, Egan T. Risk management in the NHS: Governance, finance and clinical risk Clinical Medicine, Journal of the Royal College of Physicians of London. 12: 25-28. PMID 22372216 |
0.01 |
|
2011 |
Hill AG, Gayle C, Egan T. Communities of clinical practice: understanding how to optimize medical student experience on a surgical rotation. Anz Journal of Surgery. 81: 661-2. PMID 22023174 DOI: 10.1111/j.1445-2197.2011.05776.x |
0.01 |
|
2011 |
Page K, Beasley JC, Olson ZH, Smyser TJ, Downey M, Kellner KF, McCord SE, Egan TS, Rhodes OE. Reducing Baylisascaris procyonis roundworm larvae in raccoon latrines. Emerging Infectious Diseases. 17: 90-3. PMID 21192862 DOI: 10.3201/Eid1701.100876 |
0.01 |
|
2011 |
Egan TM. Key intersections between HRD and management Human Resource Development Quarterly. 22: 223-234. DOI: 10.1002/hrdq.20075 |
0.01 |
|
2010 |
Tesche LJ, Feins RH, Dedmon MM, Newton KN, Egan TM, Haithcock BE, Veeramachaneni NK, Bowdish ME. Simulation experience enhances medical students' interest in cardiothoracic surgery Annals of Thoracic Surgery. 90: 1967-1974. PMID 21095347 DOI: 10.1016/j.athoracsur.2010.06.117 |
0.01 |
|
2010 |
Evon DM, Burker EJ, Galanko JA, Dedert E, Egan TM. Depressive symptoms and mortality in lung transplant. Clinical Transplantation. 24: E201-6. PMID 20438580 DOI: 10.1111/J.1399-0012.2010.01236.X |
0.01 |
|
2010 |
Egan TD. Editorial I: Exploring the frontiers of propofol formulation strategy: Is there life beyond the milky way? British Journal of Anaesthesia. 104: 533-535. PMID 20400610 DOI: 10.1093/bja/aeq059 |
0.01 |
|
2010 |
Colson Y, Egan T, Waters P, Demmy T, Rusch V. Discussion Journal of Thoracic and Cardiovascular Surgery. 140: 762-763. DOI: 10.1016/j.jtcvs.2010.06.054 |
0.01 |
|
2010 |
Marques HM, Egan TJ, De Villiers KA. Structure and function: Insights into bioinorganic systems from molecular mechanics calculations Structure and Function. 87-109. DOI: 10.1007/978-90-481-2888-4-4 |
0.01 |
|
2010 |
Jaye C, Egan T, Smith-Han K. Learning to fit in on the surgical ward Journal of Primary Health Care. 2: 350. |
0.01 |
|
2009 |
Egan TJ. Artemisinin-resistant Plasmodium falciparum: Can the genie be put back in the bottle? Future Microbiology. 4: 637-639. PMID 19659418 DOI: 10.2217/fmb.09.42 |
0.01 |
|
2009 |
Webster GT, de Villiers KA, Egan TJ, Deed S, Tilley L, Tobin MJ, Bambery KR, McNaughton D, Wood BR. Discriminating the intraerythrocytic lifecycle stages of the malaria parasite using synchrotron FT-IR microspectroscopy and an artificial neural network. Analytical Chemistry. 81: 2516-24. PMID 19278236 DOI: 10.1021/Ac802291A |
0.01 |
|
2008 |
Tilden D, Kass LB, Egan TP. Thomas F. Lucy's plant collections, donated to the buffalo society of natural sciences in the early 20Th century Rhodora. 110: 484-491. DOI: 10.3119/08-11.1 |
0.01 |
|
2008 |
Carden LL, Egan TM. Human resource development and project management: Key connections Human Resource Development Review. 7: 309-338. DOI: 10.1177/1534484308320577 |
0.01 |
|
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