Keith A. Crutcher - Publications

Affiliations: 
University of Cincinnati, Cincinnati, OH 
Area:
Neuroscience Biology

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Pettigrew DB, Singh N, Kirthivasan S, Crutcher KA. The Role of Tissue Geometry in Spinal Cord Regeneration. Medicina (Kaunas, Lithuania). 58. PMID 35454380 DOI: 10.3390/medicina58040542  0.716
2019 Pettigrew DB, Dobson CB, Isaacson LG, Leuthardt EC, Lilley HN, Suidan GL, Crutcher KA. Segregated neural explants exhibit co-oriented, asymmetric, neurite outgrowth. Plos One. 14: e0216263. PMID 31487284 DOI: 10.1371/Journal.Pone.0216263  0.728
2010 Richeri A, Bianchimano P, Crutcher KA, Brauer MM. Reduced sympathetic neurite outgrowth on uterine tissue sections from rats treated with estrogen. Cell and Tissue Research. 340: 287-301. PMID 20387079 DOI: 10.1007/S00441-010-0956-X  0.392
2008 Shelton SB, Pettigrew DB, Hermann AD, Zhou W, Sullivan PM, Crutcher KA, Strauss KI. A simple, efficient tool for assessment of mice after unilateral cortex injury. Journal of Neuroscience Methods. 168: 431-42. PMID 18164073 DOI: 10.1016/J.Jneumeth.2007.11.003  0.686
2007 Al-Shawi R, Hafner A, Chun S, Raza S, Crutcher K, Thrasivoulou C, Simons P, Cowen T. ProNGF, sortilin, and age-related neurodegeneration. Annals of the New York Academy of Sciences. 1119: 208-15. PMID 18056969 DOI: 10.1196/Annals.1404.024  0.41
2007 Pettigrew DB, Li YQ, Kuntz C, Crutcher KA. Global expression of NGF promotes sympathetic axonal growth in CNS white matter but does not alter its parallel orientation. Experimental Neurology. 203: 95-109. PMID 16989811 DOI: 10.1016/J.Expneurol.2006.07.026  0.759
2006 Zhou W, Scott SA, Shelton SB, Crutcher KA. Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease. Neuroscience. 143: 689-701. PMID 16997486 DOI: 10.1016/J.Neuroscience.2006.08.019  0.3
2006 Dhanoa NK, Krol KM, Jahed A, Crutcher KA, Kawaja MD. Null mutations for exon III and exon IV of the p75 neurotrophin receptor gene enhance sympathetic sprouting in response to elevated levels of nerve growth factor in transgenic mice. Experimental Neurology. 198: 416-26. PMID 16488412 DOI: 10.1016/J.Expneurol.2005.12.022  0.405
2005 Bierl MA, Jones EE, Crutcher KA, Isaacson LG. 'Mature' nerve growth factor is a minor species in most peripheral tissues. Neuroscience Letters. 380: 133-7. PMID 15854765 DOI: 10.1016/J.Neulet.2005.01.029  0.374
2004 Busciglio J, Brady S, Takashima A, Klein P, Kim L, LaFerla F, Geula C, Stokely M, Tezapsidis N, Gouras G, Strobel G, Crutcher K, Forero D. Axonal transport hypothesis moves on to implicate presenilin: Alzheimer research forum live discussion Journal of Alzheimer's Disease. 6: 537-545. PMID 15573458 DOI: 10.3233/Jad-2004-6511  0.337
2004 Marques MA, Owens PA, Crutcher KA. Progress toward identification of protease activity involved in proteolysis of apolipoprotein e in human brain. Journal of Molecular Neuroscience : Mn. 24: 73-80. PMID 15314253 DOI: 10.1385/Jmn:24:1:073  0.331
2003 Chalar C, Richeri A, Viettro L, Chávez-Genaro R, Bianchimano P, Marmol NM, Crutcher K, Burnstock G, Cowen T, Brauer MM. Plasticity in developing rat uterine sensory nerves: the role of NGF and TrkA. Cell and Tissue Research. 314: 191-205. PMID 13680358 DOI: 10.1007/S00441-003-0799-9  0.38
2003 Cowen T, Woodhoo A, Sullivan CD, Jolly R, Crutcher KA, Wyatt S, Michael GJ, Orike N, Gatzinsky K, Thrasivoulou C. Reduced age-related plasticity of neurotrophin receptor expression in selected sympathetic neurons of the rat. Aging Cell. 2: 59-69. PMID 12882335 DOI: 10.1046/J.1474-9728.2003.00035.X  0.356
2002 Kudwa AE, Shoemaker SE, Crutcher KA, Isaacson LG. Evidence for reduced accumulation of exogenous neurotrophin by aged sympathetic neurons. Brain Research. 948: 24-32. PMID 12383952 DOI: 10.1016/S0006-8993(02)02945-1  0.404
2002 Chávez-Genaro R, Crutcher K, Viettro L, Richeri A, Coirolo N, Burnstock G, Cowen T, Brauer MM. Differential effects of oestrogen on developing and mature uterine sympathetic nerves. Cell and Tissue Research. 308: 61-73. PMID 12012206 DOI: 10.1007/S00441-002-0521-3  0.368
2002 Crutcher KA. Aging and neuronal plasticity: lessons from a model. Autonomic Neuroscience : Basic & Clinical. 96: 25-32. PMID 11911499 DOI: 10.1016/S1566-0702(01)00373-3  0.382
2001 Pettigrew DB, Crutcher KA. Myelin contributes to the parallel orientation of axonal growth on white matter in vitro. Bmc Neuroscience. 2: 9. PMID 11399205 DOI: 10.1186/1471-2202-2-9  0.737
2001 Pettigrew DB, Shockley KP, Crutcher KA. Disruption of spinal cord white matter and sciatic nerve geometry inhibits axonal growth in vitro in the absence of glial scarring. Bmc Neuroscience. 2: 8. PMID 11399204 DOI: 10.1186/1471-2202-2-8  0.757
2000 Krol KM, Crutcher KA, Kalisch BE, Rylett RJ, Kawaja MD. Absence of p75(NTR) expression reduces nerve growth factor immunolocalization in cholinergic septal neurons. The Journal of Comparative Neurology. 427: 54-66. PMID 11042591 DOI: 10.1002/1096-9861(20001106)427:1<54::Aid-Cne4>3.0.Co;2-F  0.351
2000 Pettigrew DB, Levin L, Crutcher KA. Sympathetic neurite growth on central nervous system sections is region-specific and unaltered by aging. Neurobiology of Aging. 21: 629-38. PMID 11016531 DOI: 10.1016/S0197-4580(00)00155-X  0.723
2000 Shafer AJ, Crutcher KA, Isaacson LG. Remodeling of adult sensory axons in the superior cervical ganglion in response to exogenous nerve growth factor. Brain Research. 864: 252-62. PMID 10802032 DOI: 10.1016/S0006-8993(00)02163-6  0.432
1999 Kuchela GA, Crutcher KA, Naheed U, Thrasivoulou C, Cowen T. NGF expression in the aged rat pineal gland does not correlate with loss of sympathetic axonal branches and varicosities Neurobiology of Aging. 20: 685-693. PMID 10674435 DOI: 10.1016/S0197-4580(99)00064-0  0.442
1999 Pettigrew DB, Crutcher KA. White matter of the CNS supports or inhibits neurite outgrowth in vitro depending on geometry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8358-66. PMID 10493737 DOI: 10.1523/Jneurosci.19-19-08358.1999  0.752
1999 Walsh GS, Krol KM, Crutcher KA, Kawaja MD. Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4155-68. PMID 10234043 DOI: 10.1523/Jneurosci.19-10-04155.1999  0.455
1998 Isaacson LG, Crutcher KA. Uninjured aged sympathetic neurons sprout in response to exogenous NGF in vivo. Neurobiology of Aging. 19: 333-9. PMID 9733166 DOI: 10.1016/S0197-4580(98)00073-6  0.442
1998 Tolar M, Scott SA, Crutcher KA. Sympathetic neurite outgrowth is greater on plaque-poor vs. plaque-rich regions of Alzheimer's disease cryostat sections. Brain Research. 787: 49-58. PMID 9518548 DOI: 10.1016/S0006-8993(97)01455-8  0.353
1998 Joshi SN, Crutcher KA. Rat microglia exhibit increased density on Alzheimer's plaques in vitro. Experimental Neurology. 149: 42-50. PMID 9454613 DOI: 10.1006/Exnr.1997.6678  0.333
1997 Kawaja MD, Crutcher KA. Sympathetic axons invade the brains of mice overexpressing nerve growth factor. The Journal of Comparative Neurology. 383: 60-72. PMID 9184986 DOI: 10.1002/(Sici)1096-9861(19970623)383:1<60::Aid-Cne5>3.0.Co;2-J  0.468
1996 Marques MA, Tolar M, Harmony JA, Crutcher KA. A thrombin cleavage fragment of apolipoprotein E exhibits isoform-specific neurotoxicity. Neuroreport. 7: 2529-32. PMID 8981417 DOI: 10.1097/00001756-199611040-00025  0.303
1996 Cowen T, Gavazzi I, Weingartner J, Crutcher KA. Levels of NGF protein do not correlate with changes in innervation of the rat iris in old age Neuroreport. 7: 2216-2220. PMID 8930992 DOI: 10.1097/00001756-199609020-00032  0.369
1996 Fahnestock M, Scott SA, Jetté N, Weingartner JA, Crutcher KA. Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex. Brain Research. Molecular Brain Research. 42: 175-8. PMID 8915599 DOI: 10.1016/S0169-328X(96)00193-3  0.325
1996 Tian X, Scott SA, Weingartner J, Crutcher KA. Enhanced sympathetic neurite outgrowth on rat hippocampal tissue sections following septal lesions. Brain Research. 725: 111-4. PMID 8828593 DOI: 10.1016/0006-8993(96)00285-5  0.354
1996 Isaacson LG, Schwenk KL, Billieu SC, Crutcher KA. Sympathetic response to intracranial NGF infusion in the absence of afferent input: axonal sprouting without neurotransmitter production. Experimental Neurology. 141: 57-66. PMID 8797668 DOI: 10.1006/exnr.1996.0139  0.363
1995 Isaacson LG, Ondris D, Crutcher KA. Plasticity of mature sensory cerebrovascular axons following intracranial infusion of nerve growth factor. The Journal of Comparative Neurology. 361: 451-60. PMID 8550892 DOI: 10.1002/Cne.903610309  0.452
1995 Isaacson LG, Crutcher KA. The duration of sprouted cerebrovascular axons following intracranial infusion of nerve growth factor. Experimental Neurology. 131: 174-9. PMID 7895818 DOI: 10.1016/0014-4886(95)90039-X  0.442
1995 Scott SA, Mufson EJ, Weingartner JA, Skau KA, Crutcher KA. Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6213-21. PMID 7666203 DOI: 10.1523/Jneurosci.15-09-06213.1995  0.361
1995 Yu C, Crutcher KA. Nerve growth factor immunoreactivity and sympathetic sprouting in the rat hippocampal formation. Brain Research. 672: 55-67. PMID 7538420 DOI: 10.1016/0006-8993(94)01344-H  0.424
1994 Scott SA, Liang S, Weingartner JA, Crutcher KA. Increased NGF-like activity in young but not aged rat hippocampus after septal lesions. Neurobiology of Aging. 15: 337-46. PMID 7936058 DOI: 10.1016/0197-4580(94)90029-9  0.358
1994 Scott SA, Crutcher KA. Nerve growth factor and Alzheimer's disease. Reviews in the Neurosciences. 5: 179-211. PMID 7889213 DOI: 10.1515/Revneuro.1994.5.3.179  0.384
1993 Crutcher KA, Scott SA, Liang S, Everson WV, Weingartner J. Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2540-50. PMID 8501520 DOI: 10.1523/Jneurosci.13-06-02540.1993  0.344
1993 Carpenter MK, Crutcher KA, Kater SB. An analysis of the effects of Alzheimer's plaques on living neurons. Neurobiology of Aging. 14: 207-15. PMID 7686640 DOI: 10.1016/0197-4580(93)90002-S  0.384
1992 Liang S, Crutcher KA. Neuronal migration on laminin in vitro. Brain Research. Developmental Brain Research. 66: 127-32. PMID 1600626 DOI: 10.1016/0165-3806(92)90148-P  0.318
1992 Isaacson LG, Saffran BN, Crutcher KA. Nerve growth factor-induced sprouting of mature, uninjured sympathetic axons. The Journal of Comparative Neurology. 326: 327-36. PMID 1469116 DOI: 10.1002/Cne.903260302  0.435
1991 Weil SM, Madison RD, Crutcher KA. Collagen nerve guide tubes in the rat septohippocampal pathway. Restorative Neurology and Neuroscience. 3: 167-75. PMID 21551634 DOI: 10.3233/Rnn-1991-3401  0.445
1991 Crutcher KA, Weingartner J. Hippocampal NGF levels are not reduced in the aged Fischer 344 rat. Neurobiology of Aging. 12: 449-54. PMID 1770979 DOI: 10.1016/0197-4580(91)90072-R  0.323
1991 Crutcher KA, Neaderhauser J, Schmidt P, Weingartner J. Neurite outgrowth on postmortem human brain cryostat sections: studies of non-Alzheimer's and Alzheimer's tissue. Experimental Neurology. 114: 228-36. PMID 1748196 DOI: 10.1016/0014-4886(91)90039-F  0.387
1990 Crutcher KA. Age-related decrease in sympathetic sprouting is primarily due to decreased target receptivity: implications for understanding brain aging. Neurobiology of Aging. 11: 175-83. PMID 2362650 DOI: 10.1016/0197-4580(90)90543-9  0.373
1990 Saffran BN, Crutcher KA. NGF-induced remodeling of mature uninjured axon collaterals. Brain Research. 525: 11-20. PMID 2245317 DOI: 10.1016/0006-8993(90)91315-8  0.442
1990 Isaacson LG, Saffran BN, Crutcher KA. Intracerebral NGF infusion induces hyperinnervation of cerebral blood vessels. Neurobiology of Aging. 11: 51-5. PMID 2183082 DOI: 10.1016/0197-4580(90)90062-5  0.46
1990 Crutcher KA. The regulation of axonal growth in the mature mammalian nervous system. Acta Neurobiologiae Experimentalis. 50: 115-24. PMID 2130633  0.357
1989 Crutcher KA. Tissue sections from the mature rat brain and spinal cord as substrates for neurite outgrowth in vitro: extensive growth on gray matter but little growth on white matter. Experimental Neurology. 104: 39-54. PMID 2924869 DOI: 10.1016/0014-4886(89)90007-1  0.445
1989 Crutcher KA, Privitera M. Axonal regeneration on mature human brain tissue sections in culture. Annals of Neurology. 26: 580-3. PMID 2817832 DOI: 10.1002/Ana.410260414  0.428
1989 Collins F, Crutcher KA. Sustained elevation in hippocampal NGF-like biological activity following medial septal lesions in the rat Brain Research. 490: 355-360. PMID 2765870 DOI: 10.1016/0006-8993(89)90254-0  0.34
1989 Saffran BN, Woo JE, Mobley WC, Crutcher KA. Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth. Brain Research. 492: 245-54. PMID 2752299 DOI: 10.1016/0006-8993(89)90907-4  0.477
1988 Crutcher KA, Marfurt CF. Nonregenerative axonal growth within the mature mammalian brain: ultrastructural identification of sympathohippocampal sprouts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 2289-302. PMID 3249226  0.34
1987 Crutcher KA. Sympathetic sprouting in the central nervous system: a model for studies of axonal growth in the mature mammalian brain. Brain Research. 434: 203-33. PMID 3555709 DOI: 10.1016/0165-0173(87)90013-0  0.37
1986 Crutcher KA, Collins F. Entorhinal lesions result in increased nerved growth factor-like growth-promoting activity in medium conditioned by hippocampal slices Brain Research. 399: 383-389. PMID 3828773 DOI: 10.1016/0006-8993(86)91533-7  0.363
1986 Crutcher KA. The role of growth factors in neuronal development and plasticity. Crc Critical Reviews in Clinical Neurobiology. 2: 297-333. PMID 3536312  0.306
1984 Gibby WA, Crutcher KA. Absence of sympathetic sprouting in the rat olfactory bulb after cholinergic denervation. Experimental Neurology. 84: 386-95. PMID 6714350 DOI: 10.1016/0014-4886(84)90235-8  0.33
1982 Crutcher KA. Histochemical studies of sympathetic sprouting: fluorescence morphology of noradrenergic axons. Brain Research Bulletin. 9: 501-8. PMID 7172037 DOI: 10.1016/0361-9230(82)90158-7  0.364
1982 Crutcher KA, Davis JN. Target regulation of sympathetic sprouting in the rat hippocampal formation. Experimental Neurology. 75: 347-59. PMID 7106218 DOI: 10.1016/0014-4886(82)90166-2  0.536
1981 Crutcher KA, Davis JN. Sympathohippocampal sprouting is directed by a target tropic factor. Brain Research. 204: 410-4. PMID 7459636 DOI: 10.1016/0006-8993(81)90599-0  0.497
1981 Crutcher KA, Madison R, Davis JN. A study of the rat septohippocampal pathway using anterograde transport of horseradish peroxidase. Neuroscience. 6: 1961-73. PMID 6272155 DOI: 10.1016/0306-4522(81)90036-1  0.493
1981 Madison R, Crutcher KA, Davis JN. Sympathohippocampal neurons are inside the blood--brain barrier. Brain Research. 213: 183-9. PMID 6165441 DOI: 10.1016/0006-8993(81)91259-2  0.493
1981 Crutcher KA, Brothers L, Davis JN. Sympathetic noradrenergic sprouting in response to central cholinergic denervation; a histochemical study of neuronal sprouting in the rat hippocampal formation. Brain Research. 210: 115-28. PMID 6164438 DOI: 10.1016/0006-8993(81)90889-1  0.548
1981 Crutcher KA, Davis JN. Sympathetic noradrenergic sprouting in response to central cholinergic denervation Trends in Neurosciences. 4: 70-72. DOI: 10.1016/0166-2236(81)90024-2  0.548
1980 Crutcher KA, Davis JN. Noradrenergic sprouting in response to cholinergic denervation: the sympathohabenular connection. Experimental Neurology. 70: 187-91. PMID 7418768 DOI: 10.1016/0014-4886(80)90017-5  0.518
1980 Giron LT, Crutcher KA, Davis JN. Lymph nodes--a possible site for sympathetic neuronal regulation of immune responses. Annals of Neurology. 8: 520-5. PMID 6254440 DOI: 10.1002/Ana.410080509  0.432
1980 Crutcher KA, Davis JN. Hippocampal alpha- and beta-adrenergic receptors: comparison of [3H]dihydroalprenolol and [3H]WB 4101 binding with noradrenergic innervation in the rat. Brain Research. 182: 107-17. PMID 6243229 DOI: 10.1016/0006-8993(80)90834-3  0.453
1979 Crutcher KA, Brothers L, Davis JN. Sprouting of sympathetic nerves in the absence of afferent input. Experimental Neurology. 66: 778-83. PMID 488252 DOI: 10.1016/0014-4886(79)90221-8  0.545
1979 Wagner HR, Crutcher KA, Davis JN. Chronic estrogen treatment decreases beta-adrenergic responses in rat cerebral cortex. Brain Research. 171: 147-51. PMID 223732 DOI: 10.1016/0006-8993(79)90741-8  0.436
1979 Felten DL, Crutcher KA. Neuronal‐vascular relationships in the raphe nuclei, locus coeruleus, and substantia nigra in primates American Journal of Anatomy. 155: 467-481. PMID 114041 DOI: 10.1002/Aja.1001550405  0.324
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