Neil S. Greenspan - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Microbiology Biology, Immunology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Greenspan NS. Epitopes, paratopes, and other topes 30 years on: Understanding what we are talking about. Human Immunology. 84: 429-438. PMID 37407356 DOI: 10.1016/j.humimm.2023.06.006  0.32
2020 Greenspan NS. A Disquisition on MHC Restriction and T Cell Recognition in Five Acts. Viral Immunology. 33: 153-159. PMID 32286186 DOI: 10.1089/Vim.2019.0182  0.397
2017 Greenspan NS. Celebrating More Than a Century of Research on Antibodies: Affirmation Through Negation via Complex Formation. Pathogens & Immunity. 2: 60-65. PMID 28529995 DOI: 10.20411/pai.v2i1.198  0.313
2017 Pohlmeyer C, McCarthy P, Greenspan NS, Wald D. P216 Case of suspected hyperacute rental transplant rejection due to angiotensin II type 1 receptor antibodies Human Immunology. 78: 215. DOI: 10.1016/J.Humimm.2017.06.276  0.392
2016 Vela Ramirez JE, Tygrett LT, Hao J, Habte HH, Cho MW, Greenspan NS, Waldschmidt TJ, Narasimhan B. Polyanhydride Nanovaccines Induce Germinal Center B Cell Formation and Sustained Serum Antibody Responses. Journal of Biomedical Nanotechnology. 12: 1303-11. PMID 27319223 DOI: 10.1166/Jbn.2016.2242  0.48
2016 Janda A, Bowen A, Greenspan NS, Casadevall A. Ig Constant Region Effects on Variable Region Structure and Function. Frontiers in Microbiology. 7: 22. PMID 26870003 DOI: 10.3389/Fmicb.2016.00022  0.471
2016 Vela Ramirez JE, Tygrett LT, Hao J, Habte HH, Cho MW, Greenspan NS, Waldschmidt TJ, Narasimhan B. Polyanhydride nanovaccines induce germinal center B cell formation and sustained serum antibody responses Journal of Biomedical Nanotechnology. 12: 1303-1311. DOI: 10.1166/jbn.2016.2242  0.477
2015 Greenspan NS, Sheth AK, Desai V. HIV vaccine development and broadly neutralizing antibodies. Evolution, Medicine, and Public Health. 2015: 75. PMID 25712776 DOI: 10.1093/Emph/Eov004  0.364
2014 Greenspan NS. Design Challenges for HIV-1 Vaccines Based on Humoral Immunity. Frontiers in Immunology. 5: 335. PMID 25076950 DOI: 10.3389/Fimmu.2014.00335  0.472
2012 Greenspan NS, Lu MA, Shipley JW, Ding X, Li Q, Sultana D, Kollaros M, Schreiber JR, Fu P, Putterman C, Emancipator SN. IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/lpr mice. Biology Direct. 7: 3. PMID 22248284 DOI: 10.1186/1745-6150-7-3  0.476
2011 Gor DO, Ding X, Li Q, Sultana D, Mambula SS, Bram RJ, Greenspan NS. Enhanced immunogenicity of pneumococcal surface adhesin A (PsaA) in mice via fusion to recombinant human B lymphocyte stimulator (BLyS). Biology Direct. 6: 9. PMID 21306646 DOI: 10.1186/1745-6150-6-9  0.318
2010 Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, et al. PrP conformational transitions alter species preference of a PrP-specific antibody. The Journal of Biological Chemistry. 285: 13874-84. PMID 20194495 DOI: 10.1074/Jbc.M109.088831  0.439
2010 Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, et al. Reply to Kascsak: Definition of the PrP 3F4 epitope revisited Journal of Biological Chemistry. 285: le6. DOI: 10.1074/Jbc.N109.088831  0.403
2007 Kaur K, Chowdhury S, Greenspan NS, Schreiber JR. Decreased expression of tumor necrosis factor family receptors involved in humoral immune responses in preterm neonates. Blood. 110: 2948-54. PMID 17634409 DOI: 10.1182/Blood-2007-01-069245  0.422
2007 Greenspan NS. Conceptualizing immune responsiveness. Nature Immunology. 8: 5-7. PMID 17179961 DOI: 10.1038/Ni0107-5  0.362
2006 Greenspan NS, Schroeder HW. Recognition reversal in a spineless scrounger. Nature Immunology. 7: 797-8. PMID 16855603 DOI: 10.1038/Ni0806-797  0.356
2006 Gor DO, Ding X, Li Q, Greenspan NS. Genetic fusion of three tandem copies of murine C3d sequences to diphtheria toxin fragment B elicits a decreased fragment B-specific antibody response. Immunology Letters. 102: 38-49. PMID 16105692 DOI: 10.1016/J.Imlet.2005.06.020  0.468
2005 Gor DO, Ding X, Briles DE, Jacobs MR, Greenspan NS. Relationship between surface accessibility for PpmA, PsaA, and PspA and antibody-mediated immunity to systemic infection by Streptococcus pneumoniae. Infection and Immunity. 73: 1304-12. PMID 15731027 DOI: 10.1128/Iai.73.3.1304-1312.2005  0.472
2004 Poggio ED, Clemente M, Riley J, Roddy M, Greenspan NS, Dejelo C, Najafian N, Sayegh MH, Hricik DE, Heeger PS. Alloreactivity in renal transplant recipients with and without chronic allograft nephropathy. Journal of the American Society of Nephrology : Jasn. 15: 1952-60. PMID 15213286 DOI: 10.1097/01.Asn.0000129980.83334.79  0.415
2003 McCool TL, Schreiber JR, Greenspan NS. Genetic variation influences the B-cell response to immunization with a pneumococcal polysaccharide conjugate vaccine. Infection and Immunity. 71: 5402-6. PMID 12933893 DOI: 10.1128/Iai.71.9.5402-5406.2003  0.766
2003 Kamboj KK, Kirchner HL, Kimmel R, Greenspan NS, Schreiber JR. Significant variation in serotype-specific immunogenicity of the seven-valent Streptococcus pneumoniae capsular polysaccharide-CRM197 conjugate vaccine occurs despite vigorous T cell help induced by the carrier protein. The Journal of Infectious Diseases. 187: 1629-38. PMID 12721943 DOI: 10.1086/374785  0.519
2002 Gebauer BS, Hricik DE, Atallah A, Bryan K, Riley J, Tary-Lehmann M, Greenspan NS, Dejelo C, Boehm BO, Hering BJ, Heeger PS. Evolution of the enzyme-linked immunosorbent spot assay for post-transplant alloreactivity as a potentially useful immune monitoring tool. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2: 857-66. PMID 12392292 DOI: 10.1034/J.1600-6143.2002.20908.X  0.3
2002 Gor DO, Ding X, Li Q, Schreiber JR, Dubinsky M, Greenspan NS. Enhanced immunogenicity of pneumococcal surface adhesin A by genetic fusion to cytokines and evaluation of protective immunity in mice. Infection and Immunity. 70: 5589-95. PMID 12228286 DOI: 10.1128/Iai.70.10.5589-5595.2002  0.467
2002 McLay J, Leonard E, Petersen S, Shapiro D, Greenspan NS, Schreiber JR. Gamma 3 gene-disrupted mice selectively deficient in the dominant IgG subclass made to bacterial polysaccharides. II. Increased susceptibility to fatal pneumococcal sepsis due to absence of anti-polysaccharide IgG3 is corrected by induction of anti-polysaccharide IgG1. Journal of Immunology (Baltimore, Md. : 1950). 168: 3437-43. PMID 11907102 DOI: 10.4049/Jimmunol.168.7.3437  0.497
2001 Kamboj KK, King CL, Greenspan NS, Kirchner HL, Schreiber JR. Immunization with Haemophilus influenzae type b-CRM(197) conjugate vaccine elicits a mixed Th1 and Th2 CD(4+) T cell cytokine response that correlates with the isotype of antipolysaccharide antibody. The Journal of Infectious Diseases. 184: 931-5. PMID 11528593 DOI: 10.1086/323342  0.509
2001 Greenspan NS. Affinity, complementarity, cooperativity, and specificity in antibody recognition Current Topics in Microbiology and Immunology. 260: 65-85. PMID 11443882 DOI: 10.1007/978-3-662-05783-4_5  0.452
2000 Greenspan NS. Dimensions of antigen recognition and lewels of immunological specificity Advances in Cancer Research. 80: 147-187. PMID 11034543 DOI: 10.1016/S0065-230X(01)80015-4  0.369
2000 Chu RS, McCool T, Greenspan NS, Schreiber JR, Harding CV. CpG oligodeoxynucleotides act as adjuvants for pneumococcal polysaccharide-protein conjugate vaccines and enhance antipolysaccharide immunoglobulin G2a (IgG2a) and IgG3 antibodies. Infection and Immunity. 68: 1450-6. PMID 10678959 DOI: 10.1128/Iai.68.3.1450-1456.2000  0.784
1999 McCool TL, Harding CV, Greenspan NS, Schreiber JR. B- and T-cell immune responses to pneumococcal conjugate vaccines: divergence between carrier- and polysaccharide-specific immunogenicity. Infection and Immunity. 67: 4862-9. PMID 10456942 DOI: 10.1128/Iai.67.9.4862-4869.1999  0.786
1999 McCool TL, Harding CV, Greenspan NS, Schreiber JR. B- and T-Cell Immune Responses to Pneumococcal Conjugate Vaccines: Divergence between Carrier- and Polysaccharide-Specific Immunogenicity Infection and Immunity. 67: 4862-4869. DOI: 10.1128/iai.67.9.4862-4869.1999  0.787
1998 Pinilla C, Appel JR, Campbell GD, Buencamino J, Benkirane N, Muller S, Greenspan NS. All-D peptides recognized by an anti-carbohydrate antibody identified from a positional scanning library. Journal of Molecular Biology. 283: 1013-25. PMID 9799640 DOI: 10.1006/Jmbi.1998.2137  0.419
1998 Shapiro DA, Threadgill DS, Copfer MJ, Corey DA, McCool TL, McCormick LL, Magnuson TR, Greenspan NS, Schreiber JR. Gamma 3 gene-disrupted mice selectively deficient in the dominant IgG subclass made to bacterial polysaccharides undergo normal isotype switching after immunization with polysaccharide-protein conjugate vaccines. Journal of Immunology (Baltimore, Md. : 1950). 161: 3393-9. PMID 9759856  0.771
1998 Threadgill DS, McCormick LL, McCool TL, Greenspan NS, Schreiber JR. Mitogenic synthetic polynucleotides suppress the antibody response to a bacterial polysaccharide. Vaccine. 16: 76-82. PMID 9607013 DOI: 10.1016/S0264-410X(97)00151-5  0.769
1997 Harris SL, Craig L, Mehroke JS, Rashed M, Zwick MB, Kenar K, Toone EJ, Greenspan N, Auzanneau FI, Marino-Albernas JR, Pinto BM, Scott JK. Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. Proceedings of the National Academy of Sciences of the United States of America. 94: 2454-9. PMID 9122216 DOI: 10.1073/Pnas.94.6.2454  0.39
1995 Ubol S, Levine B, Lee SH, Greenspan NS, Griffin DE. Roles of immunoglobulin valency and the heavy-chain constant domain in antibody-mediated downregulation of Sindbis virus replication in persistently infected neurons Journal of Virology. 69: 1990-1993. PMID 7853547 DOI: 10.1128/Jvi.69.3.1990-1993.1995  0.314
1995 Greenspan NS, Cooper LJN. Complementarity, specificity and the nature of epitopes and paratopes in multivalent intereactions Immunology Today. 16: 226-230. PMID 7540013 DOI: 10.1016/0167-5699(95)80164-2  0.379
1994 Roux KH, Greenspan NS. Monitoring the formation of soluble immune complexes composed of idiotype and anti-idiotype antibodies by electron microscopy Molecular Immunology. 31: 599-606. PMID 8196670 DOI: 10.1016/0161-5890(94)90167-8  0.47
1994 Huang JH, Getty RR, Chisari FV, Fowler P, Greenspan NS, Tykocinski ML. Protein transfer of preformed MHC-peptide complexes sensitizes target cells to T cell cytolysis Immunity. 1: 607-613. PMID 7600289 DOI: 10.1016/1074-7613(94)90050-7  0.351
1994 Shikhman AR, Greenspan NS, Cunningham MW. Cytokeratin peptide SFGSGFGGGY mimics N-acetyl-β-D-glucosamine in reaction with antibodies and lectins, and induces in vivo anti-carbohydrate antibody response Journal of Immunology. 153: 5593-5606. PMID 7527445  0.318
1994 Cooper LJN, Robertson D, Granzow R, Greenspan NS. Variable domain-identical antibodies exhibit IgG subclass-related differences in affinity and kinetic constants as determined by surface plasmon resonance Molecular Immunology. 31: 577-584. PMID 7515151 DOI: 10.1016/0161-5890(94)90165-1  0.48
1993 Greenspan NS, Bona CA. Idiotypes: Structure and immunogenicity Faseb Journal. 7: 437-444. PMID 8462785 DOI: 10.1096/Fasebj.7.5.8462785  0.488
1993 Schreiber JR, Cooper LJN, Diehn S, Dahlhauser PA, Tosi MF, Glass DD, Patawaran M, Greenspan NS. Variable region-identical monoclonal antibodies of different igg subclass directed to pseudomonas aeruginosa lipopolysaccharide o-specific side chain function differently Journal of Infectious Diseases. 167: 221-226. PMID 8418172 DOI: 10.1093/Infdis/167.1.221  0.52
1993 Greenspan NS, Cooper LJN. Cooperative binding by mouse IgG3 antibodies: implications for functional affinity, effector function, and isotype restriction Springer Seminars in Immunopathology. 15: 275-291. PMID 8256202 DOI: 10.1007/Bf00201107  0.48
1992 Greenspan NS, Cooper LJN. Intermolecular cooperativity: a clue to why mice have IgG3? Immunology Today. 13: 164-168. PMID 1642754 DOI: 10.1016/0167-5699(92)90120-V  0.538
1992 Greenspan NS. Epitopes, paratopes and other topes: Do immunologists know what they are talking about? Bulletin De L'Institut Pasteur. 90: 267-279.  0.346
1991 Cooper LJN, Schimenti JC, Glass DD, Greenspan NS. H chain C domains influence the strength of binding of IgG for streptococcal group a carbohydrate Journal of Immunology. 146: 2659-2663. PMID 1901882  0.38
1990 Turner JR, Tartakoff AM, Greenspan NS. Cytologic assessment of nuclear and cytoplasmic O-linked N-acetylglucosamine distribution by using anti-streptococcal monoclonal antibodies Proceedings of the National Academy of Sciences of the United States of America. 87: 5608-5612. PMID 2116002 DOI: 10.1073/Pnas.87.15.5608  0.34
1989 Greenspan NS. Analyzing immunoglobulin functional anatomy with monoclonal anti-immunoglobulin antibodies Biotechniques. 7: 1086-1095. PMID 2698189  0.351
1989 Greenspan NS, Dacek DA, Cooper LJN. Cooperative binding of two antibodies to independent antigens by an Fc-dependent mechanism Faseb Journal. 3: 2203-2207. PMID 2666233 DOI: 10.1096/Fasebj.3.10.2666233  0.484
1988 Greenspan NS, Dacek DA, Cooper LJN. Fc region-dependence of IgG3 anti-streptococcal group A carbohydrate antibody functional affinity. I. The effect of temperature Journal of Immunology. 141: 4276-4282. PMID 3058803  0.331
1988 Stevens FJ, Carperos WE, Monafo WJ, Greenspan NS. Size-exclusion HPLC analysis of epitopes Journal of Immunological Methods. 108: 271-278. PMID 2450927 DOI: 10.1016/0022-1759(88)90429-2  0.344
1987 Roux KH, Monafo WJ, Davie JM, Greenspan NS. Construction of an extended three-dimensional idiotope map by electron microscopic analysis of idiotope-anti-idiotope complexes. Proceedings of the National Academy of Sciences of the United States of America. 84: 4984-8. PMID 3496600 DOI: 10.1073/Pnas.84.14.4984  0.411
1987 Monafo WJ, Greenspan NS, Cebra-Thomas JA, Davie JM. Modulation of the murine immune response to streptococcal group A carbohydrate by immunization with monoclonal anti-idiotope. Journal of Immunology (Baltimore, Md. : 1950). 139: 2702-7. PMID 3309057  0.463
1987 Greenspan NS, Monafo WJ, Davie JM. Interaction of IgG3 anti-streptococcal group A carbohydrate (GAC) antibody with streptococcal group A vaccine: enhancing and inhibiting effects of anti-GAC, anti-isotypic, and anti-idiotypic antibodies. Journal of Immunology (Baltimore, Md. : 1950). 138: 285-92. PMID 2431057  0.387
1985 Greenspan NS, Davie JM. Serologic and topographic characterization of idiotopes on murine monoclonal anti-streptococcal group A carbohydrate antibodies. Journal of Immunology (Baltimore, Md. : 1950). 134: 1065-72. PMID 3917469  0.366
1985 Greenspan NS, Davie JM. Analysis of idiotope variability as a function of distance from the binding site for anti-streptococcal group A carbohydrate antibodies. Journal of Immunology (Baltimore, Md. : 1950). 135: 1914-21. PMID 2410506  0.335
1984 Greenspan N, Doherty PC. Modification of cytotoxic T-cell response patterns by administration of hemagglutinin-specific monoclonal antibodies to mice infected with influenza A viruses. Hybridoma. 1: 149-59. PMID 6092263 DOI: 10.1089/Hyb.1.1982.1.149  0.345
1983 Greenspan N, Hurwitz JL, Doherty PC. Capacity of influenza virus-monoclonal antibody mixtures to stimulate memory and cytotoxic T lymphocyte populations. Infection and Immunity. 38: 645-50. PMID 6982868 DOI: 10.1128/Iai.38.2.645-650.1982  0.367
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