Deborah A. Shear, Ph.D. - Publications

Affiliations: 
2007 Central Michigan University, Mount Pleasant, MI, United States 
Area:
Experimental Psychology, Neuroscience Biology, Psychobiology Psychology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Boutté AM, Thangavelu B, LaValle CR, Nemes J, Gilsdorf J, Shear DA, Kamimori GH. Brain-related proteins as serum biomarkers of acute, subconcussive blast overpressure exposure: A cohort study of military personnel. Plos One. 14: e0221036. PMID 31408492 DOI: 10.1371/journal.pone.0221036  1
2019 Pandya JD, Leung LY, Yang X, Flerlage WJ, Gilsdorf JS, Deng-Bryant Y, Shear DA. Comprehensive Profile of Acute Mitochondrial Dysfunction in a Preclinical Model of Severe Penetrating TBI. Frontiers in Neurology. 10: 605. PMID 31244764 DOI: 10.3389/fneur.2019.00605  1
2019 Sanjakdar SS, Flerlage WJ, Kang HS, Napier DA, Dougherty JR, Mountney A, Gilsdorf JS, Shear DA. Differential Effects of Caffeine on Motor and Cognitive Outcomes of Penetrating Ballistic-Like Brain Injury. Military Medicine. 184: 291-300. PMID 30901408 DOI: 10.1093/milmed/usy367  1
2018 Madathil SK, Wilfred BS, Urankar SE, Yang W, Leung LY, Gilsdorf JS, Shear DA. Early Microglial Activation Following Closed-Head Concussive Injury Is Dominated by Pro-Inflammatory M-1 Type. Frontiers in Neurology. 9: 964. PMID 30498469 DOI: 10.3389/fneur.2018.00964  1
2018 Kochanek PM, Dixon CE, Mondello S, Wang KKK, Lafrenaye A, Bramlett HM, Dietrich WD, Hayes RL, Shear DA, Gilsdorf JS, Catania M, Poloyac SM, Empey PE, Jackson TC, Povlishock JT. Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond. Frontiers in Neurology. 9: 640. PMID 30131759 DOI: 10.3389/fneur.2018.00640  1
2018 DeDominicis KE, Hwang H, Cartagena CM, Shear DA, Boutté AM. Cerebrospinal Fluid Biomarkers Are Associated With Glial Fibrillary Acidic Protein and αII-spectrin Breakdown Products in Brain Tissues Following Penetrating Ballistic-Like Brain Injury in Rats. Frontiers in Neurology. 9: 490. PMID 30022967 DOI: 10.3389/fneur.2018.00490  1
2018 Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf J, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock J, et al. Serum-based phospho-neurofilament-heavy protein as theranostic biomarker in three models of traumatic brain injury: an Operation Brain Trauma Therapy (OBTT) study. Journal of Neurotrauma. PMID 29987972 DOI: 10.1089/neu.2017.5586  1
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, ... ... Shear DA, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/neu.2018.5778  1
2018 Kochanek PM, Bramlett HM, Dixon CE, Dietrich WD, Mondello S, Wang KKW, Hayes RL, Lafrenaye A, Povlishock JT, Tortella FC, Poloyac SM, Empey P, Shear DA. Operation Brain Trauma Therapy: 2016 Update. Military Medicine. 183: 303-312. PMID 29635589 DOI: 10.1093/milmed/usx184  1
2017 Madathil SK, Deng-Bryant Y, Wilfred BS, Leung LY, Gilsdorf JS, Shear DA. Alterations in brain-derived neurotrophic factor and insulin-like growth factor-1 protein levels after penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. 83: S16-S24. PMID 28628600 DOI: 10.1097/TA.0000000000001471  1
2017 Lu XM, Cao Y, Mountney A, Liao Z, Shear DA, Tortella FC. Combination therapy of levetiracetam and gabapentin against nonconvulsive seizures induced by penetrating traumatic brain injury. The Journal of Trauma and Acute Care Surgery. PMID 28452872 DOI: 10.1097/TA.0000000000001470  1
2017 Madathil SK, Deng-Bryant Y, Wilfred BS, Leung LY, Gilsdorf JS, Shear DA. Alterations in BDNF and IGF-1 protein levels following penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. PMID 28383475 DOI: 10.1097/TA.0000000000001471  1
2017 Mountney A, Boutte A, Cartagena CM, Flerlage WJ, Johnson D, Rho C, Lu XM, Yarnell AM, Marcsisin SR, Sousa J, Vuong C, Zottig VE, Leung LY, Deng-Bryant Y, Gilsdorf J, ... ... Shear DA, et al. Functional and molecular correlates following single and repeated rat closed-head concussion; indices of vulnerability following brain injury. Journal of Neurotrauma. PMID 28326890 DOI: 10.1089/neu.2016.4679  1
2017 Spurlock MS, Ahmed AI, Rivera KN, Yokobori S, Lee SW, Sam PN, Shear DA, Hefferan MP, Hazel TG, Johe KK, Gajavelli S, Tortella FC, Bullock R. Amelioration of penetrating ballistic-like brain injury induced cognitive deficits after neuronal differentiation of transplanted human neural stem cells. Journal of Neurotrauma. PMID 28249550 DOI: 10.1089/neu.2016.4602  1
2016 Browning JR, Whiteman AC, Leung LY, Lu XM, Shear DA. Air-puff induced vocalizations: A novel approach to detecting negative affective state following concussion in rats. Journal of Neuroscience Methods. PMID 27984100 DOI: 10.1016/j.jneumeth.2016.10.017  1
2016 Pandya JD, Sullivan PG, Leung LY, Tortella FC, Shear DA, Deng-Bryant Y. Advanced and High-Throughput Method for Mitochondrial Bioenergetics Evaluation in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 597-610. PMID 27604740 DOI: 10.1007/978-1-4939-3816-2_32  1
2016 Cartagena CM, Mountney A, Hwang H, Swiercz A, Rammelkamp Z, Boutte AM, Shear DA, Tortella FC, Schmid KE. Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury. Plos One. 11: e0158576. PMID 27428544 DOI: 10.1371/journal.pone.0158576  1
2016 Caudle KL, Lu XM, Mountney A, Shear DA, Tortella FC. Neuroprotection and anti-seizure effects of levetiracetam in a rat model of penetrating ballistic-like brain injury. Restorative Neurology and Neuroscience. PMID 26890099 DOI: 10.3233/RNN-150580  1
2015 Lu XM, Shear DA, Deng-Bryant Y, Leung LY, Wei G, Chen Z, Tortella FC. Comprehensive Evaluation of Neuroprotection Achieved by Extended Selective Brain Cooling Therapy in a Rat Model of Penetrating Ballistic-Like Brain Injury. Therapeutic Hypothermia and Temperature Management. PMID 26684246 DOI: 10.1089/ther.2015.0017  1
2015 Mondello S, Shear DA, Bramlett HM, Dixon CE, Schmid Maj KE, Dietrich WD, Wang KK, Hayes RL, Glushakova O, Catania M, Richieri S, Povlishock J, Tortella FC, Kochanek PM. Insight into Preclinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671651 DOI: 10.1089/neu.2015.4132  1
2015 Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid Maj KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KK, Povlishock J, Tortella FC, Kochanek PM. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671550 DOI: 10.1089/neu.2015.4131  1
2015 Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey P, Povlishock J, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, et al. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671284 DOI: 10.1089/neu.2015.4133  1
2015 Dixon CE, Bramlett HM, Dietrich WD, Shear DA, Yan HQ, Deng-Bryant Y, Mondello S, Wang KK, Hayes RL, Empey P, Povlishock J, Tortella FC, Kochanek PM. Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671075 DOI: 10.1089/neu.2015.4122  1
2015 Shear DA, Bramlett HM, Dixon CE, Dietrich WD, Deng-Bryant Y, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Kochanek PM, Tortella FC. Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670792 DOI: 10.1089/neu.2015.4115  1
2015 Bramlett HM, Dietrich WD, Dixon CE, Shear DA, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella FC, Kochanek PM. Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670694 DOI: 10.1089/neu.2015.4116  1
2015 Mountney A, Boutte A, Gilsdorf J, Lu XM, Tortella FC, Shear DA. Intravenous Administration of Simvastatin improves Cognitive Outcome following Severe Traumatic Brain Injury in Rats. Journal of Neurotrauma. PMID 26542887 DOI: 10.1089/neu.2015.4139  1
2015 Mountney A, Bramlett HM, Dixon CE, Mondello S, Dietrich WD, Wang KK, Caudle KL, Empey P, Poloyac SM, Hayes RL, Povlishock J, Tortella FC, Kochanek PM, Shear DA. Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26541177 DOI: 10.1089/neu.2015.4130  1
2015 Kochanek PM, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Schmid K, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella St FC. Operation Brain Trauma Therapy: Approach to Modeling, Therapy Evaluation, Drug Selection, and Biomarker Assessments, for a Multi-Center Pre-Clinical Drug Screening Consortium for Acute Therapies in Severe Traumatic Brain Injury. Journal of Neurotrauma. PMID 26439468 DOI: 10.1089/neu.2015.4113  1
2015 Lu XC, Shear DA, Graham PB, Bridson GW, Uttamsingh V, Chen Z, Leung LY, Tortella FC. Dual Therapeutic Effects of C-10068, a Dextromethorphan Derivative, Against Post-Traumatic Nonconvulsive Seizures and Neuroinflammation in a Rat Model of Penetrating Ballistic-Like Brain Injury. Journal of Neurotrauma. PMID 25794265 DOI: 10.1089/neu.2014.3766  1
2015 Boutté AM, Deng-Bryant Y, Johnson D, Tortella FC, Dave JR, Shear DA, Schmid KE. Serum Glial Fibrillary Acidic Protein Predicts Tissue Glial Fibrillary Acidic Protein Break-Down Products and Therapeutic Efficacy after Penetrating Ballistic-Like Brain Injury. Journal of Neurotrauma. PMID 25789543 DOI: 10.1089/neu.2014.3672  1
2015 Deng-Bryant Y, Readnower RD, Leung LY, Cunningham TL, Shear DA, Tortella FC. Treatment with amnion-derived cellular cytokine solution (ACCS) induces persistent motor improvement and ameliorates neuroinflammation in a rat model of penetrating ballistic-like brain injury. Restorative Neurology and Neuroscience. 33: 189-203. PMID 25588460 DOI: 10.3233/RNN-140455  1
2014 Cunningham TL, Cartagena CM, Lu XC, Konopko M, Dave JR, Tortella FC, Shear DA. Correlations between blood-brain barrier disruption and neuroinflammation in an experimental model of penetrating ballistic-like brain injury. Journal of Neurotrauma. 31: 505-14. PMID 24138024 DOI: 10.1089/neu.2013.2965  1
2013 Mountney A, Shear DA, Potter B, Marcsisin SR, Sousa J, Melendez V, Tortella FC, Lu XC. Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats. Journal of Neurotrauma. 30: 1973-82. PMID 23822888 DOI: 10.1089/neu.2013.3001  1
2013 Shear DA, Tortella FC. A military-centered approach to neuroprotection for traumatic brain injury. Frontiers in Neurology. 4: 73. PMID 23781213 DOI: 10.3389/fneur.2013.00073  1
2013 Leung LY, Wei G, Shear DA, Tortella FC. The acute effects of hemorrhagic shock on cerebral blood flow, brain tissue oxygen tension, and spreading depolarization following penetrating ballistic-like brain injury. Journal of Neurotrauma. 30: 1288-98. PMID 23461630 DOI: 10.1089/neu.2012.2715  1
2013 Zoltewicz JS, Mondello S, Yang B, Newsom KJ, Kobeissy F, Yao C, Lu XC, Dave JR, Shear DA, Schmid K, Rivera V, Cram T, Seaney J, Zhang Z, Wang KK, et al. Biomarkers track damage after graded injury severity in a rat model of penetrating brain injury. Journal of Neurotrauma. 30: 1161-9. PMID 23409698 DOI: 10.1089/neu.2012.2762  1
2012 Deng-Bryant Y, Chen Z, van der Merwe C, Liao Z, Dave JR, Rupp R, Shear DA, Tortella FC. Long-term administration of amnion-derived cellular cytokine suspension promotes functional recovery in a model of penetrating ballistic-like brain injury. The Journal of Trauma and Acute Care Surgery. 73: S156-64. PMID 22847087 DOI: 10.1097/TA.0b013e3182625f5f  1
2012 Ahlers ST, Vasserman-Stokes E, Shaughness MC, Hall AA, Shear DA, Chavko M, McCarron RM, Stone JR. Assessment of the effects of acute and repeated exposure to blast overpressure in rodents: toward a greater understanding of blast and the potential ramifications for injury in humans exposed to blast. Frontiers in Neurology. 3: 32. PMID 22403572 DOI: 10.3389/fneur.2012.00032  1
2012 Chen Z, Leung LY, Mountney A, Liao Z, Yang W, Lu XC, Dave J, Deng-Bryant Y, Wei G, Schmid K, Shear DA, Tortella FC. A novel animal model of closed-head concussive-induced mild traumatic brain injury: development, implementation, and characterization. Journal of Neurotrauma. 29: 268-80. PMID 21988140 DOI: 10.1089/neu.2011.2057  1
2012 Murakami Y, Wei G, Yang X, Lu XC, Leung LY, Shear DA, Tortella FC. Brain oxygen tension monitoring following penetrating ballistic-like brain injury in rats. Journal of Neuroscience Methods. 203: 115-21. PMID 21983109 DOI: 10.1016/j.jneumeth.2011.09.025  1
2011 Wei G, Lu XC, Shear DA, Yang X, Tortella FC. Neuroprotection of Selective Brain Cooling After Penetrating Ballistic-like Brain Injury in Rats. Therapeutic Hypothermia and Temperature Management. 1: 33-42. PMID 24716886 DOI: 10.1089/ther.2010.0007  1
2011 Shear DA, Tate CC, Tate MC, Archer DR, LaPlaca MC, Stein DG, Dunbar GL. Stem cell survival and functional outcome after traumatic brain injury is dependent on transplant timing and location. Restorative Neurology and Neuroscience. 29: 215-25. PMID 21697596 DOI: 10.3233/RNN-2011-0593  1
2011 Shear DA, Lu XC, Pedersen R, Wei G, Chen Z, Davis A, Yao C, Dave J, Tortella FC. Severity profile of penetrating ballistic-like brain injury on neurofunctional outcome, blood-brain barrier permeability, and brain edema formation. Journal of Neurotrauma. 28: 2185-95. PMID 21644814 DOI: 10.1089/neu.2011.1916  1
2011 Chen Z, Lu XC, Shear DA, Dave JR, Davis AR, Evangelista CA, Duffy D, Tortella FC. Synergism of human amnion-derived multipotent progenitor (AMP) cells and a collagen scaffold in promoting brain wound recovery: pre-clinical studies in an experimental model of penetrating ballistic-like brain injury. Brain Research. 1368: 71-81. PMID 20951684 DOI: 10.1016/j.brainres.2010.10.028  1
2010 Shear DA, Lu XC, Bombard MC, Pedersen R, Chen Z, Davis A, Tortella FC. Longitudinal characterization of motor and cognitive deficits in a model of penetrating ballistic-like brain injury. Journal of Neurotrauma. 27: 1911-23. PMID 20684676 DOI: 10.1089/neu.2010.1399  1
2010 Davis AR, Shear DA, Chen Z, Lu XC, Tortella FC. A comparison of two cognitive test paradigms in a penetrating brain injury model. Journal of Neuroscience Methods. 189: 84-7. PMID 20346980 DOI: 10.1016/j.jneumeth.2010.03.012  1
2009 Wei HH, Lu XC, Shear DA, Waghray A, Yao C, Tortella FC, Dave JR. NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats. Journal of Neuroinflammation. 6: 19. PMID 19656406 DOI: 10.1186/1742-2094-6-19  1
2009 Shear DA, Williams AJ, Sharrow K, Lu XC, Tortella FC. Neuroprotective profile of dextromethorphan in an experimental model of penetrating ballistic-like brain injury. Pharmacology, Biochemistry, and Behavior. 94: 56-62. PMID 19619574 DOI: 10.1016/j.pbb.2009.07.006  1
2009 Tate CC, Shear DA, Tate MC, Archer DR, Stein DG, LaPlaca MC. Laminin and fibronectin scaffolds enhance neural stem cell transplantation into the injured brain. Journal of Tissue Engineering and Regenerative Medicine. 3: 208-17. PMID 19229887 DOI: 10.1002/term.154  1
2008 Haik KL, Shear DA, Hargrove C, Patton J, Mazei-Robison M, Sandstrom MI, Dunbar GL. 7-nitroindazole attenuates 6-hydroxydopamine-induced spatial learning deficits and dopamine neuron loss in a presymptomatic animal model of Parkinson's disease. Experimental and Clinical Psychopharmacology. 16: 178-89. PMID 18489022 DOI: 10.1037/1064-1297.16.2.178  1
2004 Shear DA, Tate MC, Archer DR, Hoffman SW, Hulce VD, Laplaca MC, Stein DG. Neural progenitor cell transplants promote long-term functional recovery after traumatic brain injury. Brain Research. 1026: 11-22. PMID 15476693 DOI: 10.1016/j.brainres.2004.07.087  1
2002 Shear DA, Galani R, Hoffman SW, Stein DG. Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury. Experimental Neurology. 178: 59-67. PMID 12460608 DOI: 10.1006/exnr.2002.8020  1
2002 Tate MC, Shear DA, Hoffman SW, Stein DG, Archer DR, LaPlaca MC. Fibronectin promotes survival and migration of primary neural stem cells transplanted into the traumatically injured mouse brain. Cell Transplantation. 11: 283-95. PMID 12075994  1
2001 Tate MC, Shear DA, Hoffman SW, Stein DG, LaPlaca MC. Biocompatibility of methylcellulose-based constructs designed for intracerebral gelation following experimental traumatic brain injury. Biomaterials. 22: 1113-23. PMID 11352091 DOI: 10.1016/S0142-9612(00)00348-3  1
2000 Shear DA, Haik KL, Dunbar GL. Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats. Neuroreport. 11: 1833-7. PMID 10884028  1
2000 Haik KL, Shear DA, Schroeder U, Sabel BA, Dunbar GL. Quinolinic acid released from polymeric brain implants causes behavioral and neuroanatomical alterations in a rodent model of Huntington's disease. Experimental Neurology. 163: 430-9. PMID 10833318 DOI: 10.1006/exnr.2000.7384  1
1998 Shear DA, Dong J, Gundy CD, Haik-Creguer KL, Dunbar GL. Comparison of intrastriatal injections of quinolinic acid and 3-nitropropionic acid for use in animal models of Huntington's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 22: 1217-40. PMID 9829299 DOI: 10.1016/S0278-5846(98)00070-0  1
1998 Shear DA, Dong J, Haik-Creguer KL, Bazzett TJ, Albin RL, Dunbar GL. Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task. Experimental Neurology. 150: 305-11. PMID 9527900 DOI: 10.1006/exnr.1998.6767  1
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