Deborah A. Shear, Ph.D. - Publications

Affiliations: 
2007 Central Michigan University, Mount Pleasant, MI, United States 
Area:
Experimental Psychology, Neuroscience Biology, Psychobiology Psychology

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Year Citation  Score
2023 Jones C, Elliott B, Liao Z, Johnson Z, Ma F, Bailey ZS, Gilsdorf J, Scultetus A, Shear D, Webb K, Lee JS. PEG hydrogel containing dexamethasone-conjugated hyaluronic acid reduces secondary injury and improves motor function in a rat moderate TBI model. Experimental Neurology. 114533. PMID 37666386 DOI: 10.1016/j.expneurol.2023.114533  0.402
2023 Bailey ZS, Yang X, Cardiff K, Wang P, Houchins M, Lu XC, Cao Y, Gilsdorf J, Scultetus A, Shear D. Effects of tranexamic acid on neuropathology, electroencephalography, and cerebral fibrin deposition in a rat model of polytrauma with concomitant penetrating traumatic brain injury. Shock (Augusta, Ga.). PMID 37267223 DOI: 10.1097/SHK.0000000000002154  0.375
2022 Haidar MA, Shakkour Z, Barsa C, Tabet M, Mekhjian S, Darwish H, Goli M, Shear D, Pandya JD, Mechref Y, El Khoury R, Wang K, Kobeissy F. Mitoquinone Helps Combat the Neurological, Cognitive, and Molecular Consequences of Open Head Traumatic Brain Injury at Chronic Time Point. Biomedicines. 10. PMID 35203460 DOI: 10.3390/biomedicines10020250  0.371
2022 Tabet M, El-Kurdi M, Haidar MA, Nasrallah L, Reslan MA, Shear D, Pandya JD, El-Yazbi AF, Sabra M, Mondello S, Mechref Y, Shaito A, Wang KK, El-Khoury R, Kobeissy F. Mitoquinone supplementation alleviates oxidative stress and pathologic outcomes following repetitive mild traumatic brain injury at a chronic time point. Experimental Neurology. 351: 113987. PMID 35065054 DOI: 10.1016/j.expneurol.2022.113987  0.352
2021 Osier N, Bramlett HM, Shear DA, Mondello S, Carlson SW, Dietrich WD, Deng-Bryant Y, Wang KKW, Hayes RL, Yang Z, Empey PE, Poloyac SM, Lafrenaye AD, Povlishock J, Gilsdorf J, et al. Kollidon VA64 Treatment in Traumatic Brain Injury, Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 33843262 DOI: 10.1089/neu.2021.0089  0.349
2020 Jha R, Mondello S, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Wang KKW, Yang Z, Hayes RL, Poloyac SM, Empey PE, Lafrenaye AD, Yan HQ, Carlson SW, Povlishock J, et al. Glibenclamide Treatment in Traumatic Brain Injury-Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 33203303 DOI: 10.1089/neu.2020.7421  0.386
2020 Thangavelu B, Wilfred BS, Johnson D, Gilsdorf JS, Shear DA, Boutté AM. Penetrating Ballistic-Like Brain Injury Leads to MicroRNA Dysregulation, BACE1 Upregulation, and Amyloid Precursor Protein Loss in Lesioned Rat Brain Tissues. Frontiers in Neuroscience. 14: 915. PMID 33071724 DOI: 10.3389/Fnins.2020.00915  0.335
2020 Zusman BE, Kochanek PM, Bailey ZS, Leung LY, Vagni VA, Okonkwo DO, Puccio AM, Shutter LA, Janesko-Feldman KL, Gilsdorf JS, Shear DA, Jha RM. Multifaceted Benefit of Whole Blood Versus Lactated Ringer's Resuscitation After Traumatic Brain Injury and Hemorrhagic Shock in Mice. Neurocritical Care. PMID 32886294 DOI: 10.1007/S12028-020-01084-1  0.402
2020 Boutte A, Hook V, Thangavelu B, Sarkis G, Abbatiello B, Hook G, Jacobsen JS, Robertson CS, Gilsdorf J, Yang Z, Wang KKW, Shear DA. Penetrating Traumatic Brain Injury Triggers Subacute Dysregulation of Cathepsin B Protein Levels Independently of Cysteine Protease Activity in Brain and Cerebral Spinal Fluid. Journal of Neurotrauma. PMID 31973644 DOI: 10.1089/Neu.2019.6537  0.413
2019 Bailey ZS, Cardiff K, Yang X, Gilsdorf J, Shear D, Rasmussen TE, Leung LY. The Effects of Balloon Occlusion of the Aorta on Cerebral Blood Flow, Intracranial Pressure, and Brain Tissue Oxygen Tension in a Rodent Model of Penetrating Ballistic-Like Brain Injury. Frontiers in Neurology. 10: 1309. PMID 31920932 DOI: 10.3389/Fneur.2019.01309  0.404
2019 Hu Z, Gajavelli S, Spurlock MS, Mahavadi A, Quesada LS, Gajavelli GR, Andreoni CB, Di L, Janecki J, Lee SW, Rivera KN, Shear DA, Bullock RM. Human Neural stem cell (HNSC) Transplant Location dependent neuroprotection and motor deficit amelioration in rats with penetrating TBI (PTBI). The Journal of Trauma and Acute Care Surgery. PMID 31626023 DOI: 10.1097/Ta.0000000000002510  0.463
2019 Wilfred BS, Madathil SK, Cardiff K, Urankar S, Yang X, Hwang HM, Gilsdorf J, Shear DA, Leung LY. Alterations in peripheral organs following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury. Journal of Neurotrauma. PMID 31595817 DOI: 10.1089/Neu.2019.6570  0.452
2019 Lu XM, Browning J, Liao Z, Cao Y, Yang W, Shear DA. Post-Traumatic Epilepsy and Seizure Susceptibility in Rat Models of Penetrating and Closed-Head Brain Injury. Journal of Neurotrauma. PMID 31530242 DOI: 10.1089/Neu.2019.6573  0.416
2019 Rice MW, Pandya JD, Shear DA. Gut Microbiota as a Therapeutic Target to Ameliorate the Biochemical, Neuroanatomical, and Behavioral Effects of Traumatic Brain Injuries. Frontiers in Neurology. 10: 875. PMID 31474930 DOI: 10.3389/Fneur.2019.00875  0.472
2019 Deng-Bryant Y, Leung LY, Madathil S, Flerlage J, Yang F, Yang W, Gilsdorf J, Shear D. Chronic Cognitive Deficits and Associated Histopathology Following Closed-Head Concussive Injury in Rats. Frontiers in Neurology. 10: 699. PMID 31312174 DOI: 10.3389/Fneur.2019.00699  0.496
2019 Pandya JD, Leung LY, Yang X, Flerlage WJ, Gilsdorf JS, Deng-Bryant Y, Shear DA. Comprehensive Profile of Acute Mitochondrial Dysfunction in a Preclinical Model of Severe Penetrating TBI. Frontiers in Neurology. 10: 605. PMID 31244764 DOI: 10.3389/Fneur.2019.00605  0.37
2019 Sanjakdar SS, Flerlage WJ, Kang HS, Napier DA, Dougherty JR, Mountney A, Gilsdorf JS, Shear DA. Differential Effects of Caffeine on Motor and Cognitive Outcomes of Penetrating Ballistic-Like Brain Injury. Military Medicine. 184: 291-300. PMID 30901408 DOI: 10.1093/Milmed/Usy367  0.481
2018 Madathil SK, Wilfred BS, Urankar SE, Yang W, Leung LY, Gilsdorf JS, Shear DA. Early Microglial Activation Following Closed-Head Concussive Injury Is Dominated by Pro-Inflammatory M-1 Type. Frontiers in Neurology. 9: 964. PMID 30498469 DOI: 10.3389/Fneur.2018.00964  0.426
2018 Kochanek PM, Dixon CE, Mondello S, Wang KKK, Lafrenaye A, Bramlett HM, Dietrich WD, Hayes RL, Shear DA, Gilsdorf JS, Catania M, Poloyac SM, Empey PE, Jackson TC, Povlishock JT. Multi-Center Pre-clinical Consortia to Enhance Translation of Therapies and Biomarkers for Traumatic Brain Injury: Operation Brain Trauma Therapy and Beyond. Frontiers in Neurology. 9: 640. PMID 30131759 DOI: 10.3389/Fneur.2018.00640  0.379
2018 Leung LY, Cardiff K, Yang X, Srambical Wilfred B, Gilsdorf J, Shear D. Selective Brain Cooling Reduces Motor Deficits Induced by Combined Traumatic Brain Injury, Hypoxemia and Hemorrhagic Shock. Frontiers in Neurology. 9: 612. PMID 30123177 DOI: 10.3389/Fneur.2018.00612  0.498
2018 DeDominicis KE, Hwang H, Cartagena CM, Shear DA, Boutté AM. Cerebrospinal Fluid Biomarkers Are Associated With Glial Fibrillary Acidic Protein and αII-spectrin Breakdown Products in Brain Tissues Following Penetrating Ballistic-Like Brain Injury in Rats. Frontiers in Neurology. 9: 490. PMID 30022967 DOI: 10.3389/Fneur.2018.00490  0.452
2018 Yang Z, Zhu T, Mondello S, Akel M, Wong AT, Kothari IM, Lin F, Shear DA, Gilsdorf J, Leung LY, Bramlett HM, Dixon CE, Dietrich WD, Hayes RL, Povlishock J, et al. Serum-based phospho-neurofilament-heavy protein as theranostic biomarker in three models of traumatic brain injury: an Operation Brain Trauma Therapy (OBTT) study. Journal of Neurotrauma. PMID 29987972 DOI: 10.1089/Neu.2017.5586  0.441
2018 DeWitt D, Hawkins BE, Dixon CE, Kochanek PM, Armstead WM, Bass C', Bramlett HM, Büki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds Ii CSR, LaPlaca M, Long J, ... ... Shear DA, et al. Preclinical Testing of Therapies for Traumatic Brain Injury. Journal of Neurotrauma. PMID 29756522 DOI: 10.1089/Neu.2018.5778  0.397
2018 Kochanek PM, Bramlett HM, Dixon CE, Dietrich WD, Mondello S, Wang KKW, Hayes RL, Lafrenaye A, Povlishock JT, Tortella FC, Poloyac SM, Empey P, Shear DA. Operation Brain Trauma Therapy: 2016 Update. Military Medicine. 183: 303-312. PMID 29635589 DOI: 10.1093/Milmed/Usx184  0.402
2017 Madathil SK, Deng-Bryant Y, Wilfred BS, Leung LY, Gilsdorf JS, Shear DA. Alterations in brain-derived neurotrophic factor and insulin-like growth factor-1 protein levels after penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. 83: S16-S24. PMID 28628600 DOI: 10.1097/Ta.0000000000001471  0.401
2017 Lu XM, Cao Y, Mountney A, Liao Z, Shear DA, Tortella FC. Combination therapy of levetiracetam and gabapentin against nonconvulsive seizures induced by penetrating traumatic brain injury. The Journal of Trauma and Acute Care Surgery. PMID 28452872 DOI: 10.1097/Ta.0000000000001470  0.389
2017 Madathil SK, Deng-Bryant Y, Wilfred BS, Leung LY, Gilsdorf JS, Shear DA. Alterations in BDNF and IGF-1 protein levels following penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. PMID 28383475 DOI: 10.1097/TA.0000000000001471  0.323
2017 Mountney A, Boutte A, Cartagena CM, Flerlage WJ, Johnson D, Rho C, Lu XM, Yarnell AM, Marcsisin SR, Sousa J, Vuong C, Zottig VE, Leung LY, Deng-Bryant Y, Gilsdorf J, ... Shear DA, et al. Functional and molecular correlates following single and repeated rat closed-head concussion; indices of vulnerability following brain injury. Journal of Neurotrauma. PMID 28326890 DOI: 10.1089/Neu.2016.4679  0.512
2017 Spurlock MS, Ahmed AI, Rivera KN, Yokobori S, Lee SW, Sam PN, Shear DA, Hefferan MP, Hazel TG, Johe KK, Gajavelli S, Tortella FC, Bullock R. Amelioration of penetrating ballistic-like brain injury induced cognitive deficits after neuronal differentiation of transplanted human neural stem cells. Journal of Neurotrauma. PMID 28249550 DOI: 10.1089/Neu.2016.4602  0.44
2016 Browning JR, Whiteman AC, Leung LY, Lu XM, Shear DA. Air-puff induced vocalizations: A novel approach to detecting negative affective state following concussion in rats. Journal of Neuroscience Methods. PMID 27984100 DOI: 10.1016/J.Jneumeth.2016.10.017  0.337
2016 Leung LY, Deng-Bryant Y, Cardiff K, Winter M, Tortella F, Shear D. Neurochemical changes following combined hypoxemia and hemorrhagic shock in a rat model of penetrating ballistic-like brain injury: A microdialysis study. The Journal of Trauma and Acute Care Surgery. 81: 860-867. PMID 27769083 DOI: 10.1097/Ta.0000000000001206  0.481
2016 Pandya JD, Sullivan PG, Leung LY, Tortella FC, Shear DA, Deng-Bryant Y. Advanced and High-Throughput Method for Mitochondrial Bioenergetics Evaluation in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 597-610. PMID 27604740 DOI: 10.1007/978-1-4939-3816-2_32  0.319
2016 Deng-Bryant Y, Leung LY, Caudle K, Tortella F, Shear D. Cognitive Evaluation Using Morris Water Maze in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 539-51. PMID 27604737 DOI: 10.1007/978-1-4939-3816-2_29  0.47
2016 Leung LY, Deng-Bryant Y, Shear D, Tortella F. Experimental Models Combining TBI, Hemorrhagic Shock, and Hypoxemia. Methods in Molecular Biology (Clifton, N.J.). 1462: 445-58. PMID 27604733 DOI: 10.1007/978-1-4939-3816-2_25  0.451
2016 Cartagena CM, Mountney A, Hwang H, Swiercz A, Rammelkamp Z, Boutte AM, Shear DA, Tortella FC, Schmid KE. Subacute Changes in Cleavage Processing of Amyloid Precursor Protein and Tau following Penetrating Traumatic Brain Injury. Plos One. 11: e0158576. PMID 27428544 DOI: 10.1371/Journal.Pone.0158576  0.412
2016 Yarnell AM, Barry ES, Mountney A, Shear D, Tortella F, Grunberg NE. The Revised Neurobehavioral Severity Scale (NSS-R) for Rodents. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. 75: 9.52.1-9.52.16. PMID 27063788 DOI: 10.1002/Cpns.10  0.452
2016 Caudle KL, Lu XM, Mountney A, Shear DA, Tortella FC. Neuroprotection and anti-seizure effects of levetiracetam in a rat model of penetrating ballistic-like brain injury. Restorative Neurology and Neuroscience. PMID 26890099 DOI: 10.3233/Rnn-150580  0.448
2015 Lu XM, Shear DA, Deng-Bryant Y, Leung LY, Wei G, Chen Z, Tortella FC. Comprehensive Evaluation of Neuroprotection Achieved by Extended Selective Brain Cooling Therapy in a Rat Model of Penetrating Ballistic-Like Brain Injury. Therapeutic Hypothermia and Temperature Management. PMID 26684246 DOI: 10.1089/Ther.2015.0017  0.527
2015 Mondello S, Shear DA, Bramlett HM, Dixon CE, Schmid Maj KE, Dietrich WD, Wang KK, Hayes RL, Glushakova O, Catania M, Richieri S, Povlishock J, Tortella FC, Kochanek PM. Insight into Preclinical Models of Traumatic Brain Injury Using Circulating Brain Damage Biomarkers: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671651 DOI: 10.1089/Neu.2015.4132  0.494
2015 Browning M, Shear DA, Bramlett HM, Dixon CE, Mondello S, Schmid Maj KE, Poloyac SM, Dietrich WD, Hayes RL, Wang KK, Povlishock J, Tortella FC, Kochanek PM. Levetiracetam Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671550 DOI: 10.1089/Neu.2015.4131  0.432
2015 Kochanek PM, Bramlett HM, Shear DA, Dixon CE, Mondello S, Dietrich WD, Hayes RL, Wang KK, Poloyac SM, Empey P, Povlishock J, Mountney A, Browning M, Deng-Bryant Y, Yan HQ, et al. Synthesis of Findings, Current Investigations, and Future Directions: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671284 DOI: 10.1089/Neu.2015.4133  0.398
2015 Dixon CE, Bramlett HM, Dietrich WD, Shear DA, Yan HQ, Deng-Bryant Y, Mondello S, Wang KK, Hayes RL, Empey P, Povlishock J, Tortella FC, Kochanek PM. Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26671075 DOI: 10.1089/Neu.2015.4122  0.489
2015 Shear DA, Bramlett HM, Dixon CE, Dietrich WD, Deng-Bryant Y, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Kochanek PM, Tortella FC. Nicotinamide Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670792 DOI: 10.1089/Neu.2015.4115  0.475
2015 Bramlett HM, Dietrich WD, Dixon CE, Shear DA, Schmid Maj KE, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella FC, Kochanek PM. Erythropoietin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26670694 DOI: 10.1089/Neu.2015.4116  0.483
2015 Mountney A, Boutte A, Gilsdorf J, Lu XM, Tortella FC, Shear DA. Intravenous Administration of Simvastatin improves Cognitive Outcome following Severe Traumatic Brain Injury in Rats. Journal of Neurotrauma. PMID 26542887 DOI: 10.1089/Neu.2015.4139  0.513
2015 Mountney A, Bramlett HM, Dixon CE, Mondello S, Dietrich WD, Wang KK, Caudle KL, Empey P, Poloyac SM, Hayes RL, Povlishock J, Tortella FC, Kochanek PM, Shear DA. Simvastatin Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy. Journal of Neurotrauma. PMID 26541177 DOI: 10.1089/Neu.2015.4130  0.512
2015 Kochanek PM, Bramlett HM, Dixon CE, Shear DA, Dietrich WD, Schmid K, Mondello S, Wang KK, Hayes RL, Povlishock J, Tortella St FC. Operation Brain Trauma Therapy: Approach to Modeling, Therapy Evaluation, Drug Selection, and Biomarker Assessments, for a Multi-Center Pre-Clinical Drug Screening Consortium for Acute Therapies in Severe Traumatic Brain Injury. Journal of Neurotrauma. PMID 26439468 DOI: 10.1089/Neu.2015.4113  0.381
2015 Leung LY, Deng-Bryant Y, Shear D, Tortella F. Combined hypoxemic and hypotensive insults altered physiological responses and neurofunction in a severity-dependent manner following penetrating ballistic-like brain injury in rats. The Journal of Trauma and Acute Care Surgery. 79: S130-8. PMID 26406425 DOI: 10.1097/Ta.0000000000000785  0.486
2015 Lu XC, Shear DA, Graham PB, Bridson GW, Uttamsingh V, Chen Z, Leung LY, Tortella FC. Dual Therapeutic Effects of C-10068, a Dextromethorphan Derivative, Against Post-Traumatic Nonconvulsive Seizures and Neuroinflammation in a Rat Model of Penetrating Ballistic-Like Brain Injury. Journal of Neurotrauma. PMID 25794265 DOI: 10.1089/Neu.2014.3766  0.418
2015 Gajavelli S, Kentaro S, Diaz J, Yokobori S, Spurlock M, Diaz D, Jackson C, Wick A, Zhao W, Leung LY, Shear D, Tortella F, Bullock MR. Glucose and oxygen metabolism after penetrating ballistic-like brain injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 773-80. PMID 25669903 DOI: 10.1038/Jcbfm.2014.243  0.448
2015 Deng-Bryant Y, Readnower RD, Leung LY, Cunningham TL, Shear DA, Tortella FC. Treatment with amnion-derived cellular cytokine solution (ACCS) induces persistent motor improvement and ameliorates neuroinflammation in a rat model of penetrating ballistic-like brain injury. Restorative Neurology and Neuroscience. 33: 189-203. PMID 25588460 DOI: 10.3233/Rnn-140455  0.492
2014 Leung LY, Larimore Z, Holmes L, Cartagena C, Mountney A, Deng-Bryant Y, Schmid K, Shear D, Tortella F. The WRAIR projectile concussive impact model of mild traumatic brain injury: re-design, testing and preclinical validation. Annals of Biomedical Engineering. 42: 1618-30. PMID 24756867 DOI: 10.1007/S10439-014-1014-8  0.399
2014 Cunningham TL, Cartagena CM, Lu XC, Konopko M, Dave JR, Tortella FC, Shear DA. Correlations between blood-brain barrier disruption and neuroinflammation in an experimental model of penetrating ballistic-like brain injury. Journal of Neurotrauma. 31: 505-14. PMID 24138024 DOI: 10.1089/Neu.2013.2965  0.424
2013 Mountney A, Shear DA, Potter B, Marcsisin SR, Sousa J, Melendez V, Tortella FC, Lu XC. Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats. Journal of Neurotrauma. 30: 1973-82. PMID 23822888 DOI: 10.1089/Neu.2013.3001  0.444
2013 Shear DA, Tortella FC. A military-centered approach to neuroprotection for traumatic brain injury. Frontiers in Neurology. 4: 73. PMID 23781213 DOI: 10.3389/Fneur.2013.00073  0.423
2013 Leung LY, Wei G, Shear DA, Tortella FC. The acute effects of hemorrhagic shock on cerebral blood flow, brain tissue oxygen tension, and spreading depolarization following penetrating ballistic-like brain injury. Journal of Neurotrauma. 30: 1288-98. PMID 23461630 DOI: 10.1089/Neu.2012.2715  0.418
2013 Zoltewicz JS, Mondello S, Yang B, Newsom KJ, Kobeissy F, Yao C, Lu XC, Dave JR, Shear DA, Schmid K, Rivera V, Cram T, Seaney J, Zhang Z, Wang KK, et al. Biomarkers track damage after graded injury severity in a rat model of penetrating brain injury. Journal of Neurotrauma. 30: 1161-9. PMID 23409698 DOI: 10.1089/Neu.2012.2762  0.473
2013 Mountney A, Leung LY, Pedersen R, Shear D, Tortella F. Longitudinal assessment of gait abnormalities following penetrating ballistic-like brain injury in rats. Journal of Neuroscience Methods. 212: 1-16. PMID 22981945 DOI: 10.1016/J.Jneumeth.2012.08.025  0.503
2012 Deng-Bryant Y, Chen Z, van der Merwe C, Liao Z, Dave JR, Rupp R, Shear DA, Tortella FC. Long-term administration of amnion-derived cellular cytokine suspension promotes functional recovery in a model of penetrating ballistic-like brain injury. The Journal of Trauma and Acute Care Surgery. 73: S156-64. PMID 22847087 DOI: 10.1097/Ta.0B013E3182625F5F  0.419
2012 Ahlers ST, Vasserman-Stokes E, Shaughness MC, Hall AA, Shear DA, Chavko M, McCarron RM, Stone JR. Assessment of the effects of acute and repeated exposure to blast overpressure in rodents: toward a greater understanding of blast and the potential ramifications for injury in humans exposed to blast. Frontiers in Neurology. 3: 32. PMID 22403572 DOI: 10.3389/Fneur.2012.00032  0.398
2012 Chen Z, Leung LY, Mountney A, Liao Z, Yang W, Lu XC, Dave J, Deng-Bryant Y, Wei G, Schmid K, Shear DA, Tortella FC. A novel animal model of closed-head concussive-induced mild traumatic brain injury: development, implementation, and characterization. Journal of Neurotrauma. 29: 268-80. PMID 21988140 DOI: 10.1089/Neu.2011.2057  0.483
2012 Murakami Y, Wei G, Yang X, Lu XC, Leung LY, Shear DA, Tortella FC. Brain oxygen tension monitoring following penetrating ballistic-like brain injury in rats. Journal of Neuroscience Methods. 203: 115-21. PMID 21983109 DOI: 10.1016/J.Jneumeth.2011.09.025  0.472
2011 Wei G, Lu XC, Shear DA, Yang X, Tortella FC. Neuroprotection of Selective Brain Cooling After Penetrating Ballistic-like Brain Injury in Rats. Therapeutic Hypothermia and Temperature Management. 1: 33-42. PMID 24716886 DOI: 10.1089/Ther.2010.0007  0.485
2011 Shear DA, Tate CC, Tate MC, Archer DR, LaPlaca MC, Stein DG, Dunbar GL. Stem cell survival and functional outcome after traumatic brain injury is dependent on transplant timing and location. Restorative Neurology and Neuroscience. 29: 215-25. PMID 21697596 DOI: 10.3233/Rnn-2011-0593  0.705
2011 Shear DA, Lu XC, Pedersen R, Wei G, Chen Z, Davis A, Yao C, Dave J, Tortella FC. Severity profile of penetrating ballistic-like brain injury on neurofunctional outcome, blood-brain barrier permeability, and brain edema formation. Journal of Neurotrauma. 28: 2185-95. PMID 21644814 DOI: 10.1089/Neu.2011.1916  0.481
2011 Chen Z, Lu XC, Shear DA, Dave JR, Davis AR, Evangelista CA, Duffy D, Tortella FC. Synergism of human amnion-derived multipotent progenitor (AMP) cells and a collagen scaffold in promoting brain wound recovery: pre-clinical studies in an experimental model of penetrating ballistic-like brain injury. Brain Research. 1368: 71-81. PMID 20951684 DOI: 10.1016/J.Brainres.2010.10.028  0.451
2010 Shear DA, Lu XC, Bombard MC, Pedersen R, Chen Z, Davis A, Tortella FC. Longitudinal characterization of motor and cognitive deficits in a model of penetrating ballistic-like brain injury. Journal of Neurotrauma. 27: 1911-23. PMID 20684676 DOI: 10.1089/Neu.2010.1399  0.516
2010 Davis AR, Shear DA, Chen Z, Lu XC, Tortella FC. A comparison of two cognitive test paradigms in a penetrating brain injury model. Journal of Neuroscience Methods. 189: 84-7. PMID 20346980 DOI: 10.1016/J.Jneumeth.2010.03.012  0.479
2009 Wei HH, Lu XC, Shear DA, Waghray A, Yao C, Tortella FC, Dave JR. NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats. Journal of Neuroinflammation. 6: 19. PMID 19656406 DOI: 10.1186/1742-2094-6-19  0.47
2009 Shear DA, Williams AJ, Sharrow K, Lu XC, Tortella FC. Neuroprotective profile of dextromethorphan in an experimental model of penetrating ballistic-like brain injury. Pharmacology, Biochemistry, and Behavior. 94: 56-62. PMID 19619574 DOI: 10.1016/J.Pbb.2009.07.006  0.47
2009 Tate CC, Shear DA, Tate MC, Archer DR, Stein DG, LaPlaca MC. Laminin and fibronectin scaffolds enhance neural stem cell transplantation into the injured brain. Journal of Tissue Engineering and Regenerative Medicine. 3: 208-17. PMID 19229887 DOI: 10.1002/Term.154  0.541
2008 Haik KL, Shear DA, Hargrove C, Patton J, Mazei-Robison M, Sandstrom MI, Dunbar GL. 7-nitroindazole attenuates 6-hydroxydopamine-induced spatial learning deficits and dopamine neuron loss in a presymptomatic animal model of Parkinson's disease. Experimental and Clinical Psychopharmacology. 16: 178-89. PMID 18489022 DOI: 10.1037/1064-1297.16.2.178  0.71
2004 Shear DA, Tate MC, Archer DR, Hoffman SW, Hulce VD, Laplaca MC, Stein DG. Neural progenitor cell transplants promote long-term functional recovery after traumatic brain injury. Brain Research. 1026: 11-22. PMID 15476693 DOI: 10.1016/J.Brainres.2004.07.087  0.607
2002 Shear DA, Galani R, Hoffman SW, Stein DG. Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury. Experimental Neurology. 178: 59-67. PMID 12460608 DOI: 10.1006/Exnr.2002.8020  0.641
2002 Tate MC, Shear DA, Hoffman SW, Stein DG, Archer DR, LaPlaca MC. Fibronectin promotes survival and migration of primary neural stem cells transplanted into the traumatically injured mouse brain. Cell Transplantation. 11: 283-95. PMID 12075994 DOI: 10.3727/096020198389933  0.605
2001 Tate MC, Shear DA, Hoffman SW, Stein DG, LaPlaca MC. Biocompatibility of methylcellulose-based constructs designed for intracerebral gelation following experimental traumatic brain injury. Biomaterials. 22: 1113-23. PMID 11352091 DOI: 10.1016/S0142-9612(00)00348-3  0.631
2000 Shear DA, Haik KL, Dunbar GL. Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats. Neuroreport. 11: 1833-7. PMID 10884028 DOI: 10.1097/00001756-200006260-00007  0.712
2000 Haik KL, Shear DA, Schroeder U, Sabel BA, Dunbar GL. Quinolinic acid released from polymeric brain implants causes behavioral and neuroanatomical alterations in a rodent model of Huntington's disease. Experimental Neurology. 163: 430-9. PMID 10833318 DOI: 10.1006/Exnr.2000.7384  0.718
1998 Shear DA, Dong J, Gundy CD, Haik-Creguer KL, Dunbar GL. Comparison of intrastriatal injections of quinolinic acid and 3-nitropropionic acid for use in animal models of Huntington's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 22: 1217-40. PMID 9829299 DOI: 10.1016/S0278-5846(98)00070-0  0.648
1998 Shear DA, Dong J, Haik-Creguer KL, Bazzett TJ, Albin RL, Dunbar GL. Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task. Experimental Neurology. 150: 305-11. PMID 9527900 DOI: 10.1006/Exnr.1998.6767  0.641
Low-probability matches (unlikely to be authored by this person)
2016 Deng-Bryant Y, Readnower R, Leung LY, Tortella F, Shear D. Methods of Drug Delivery in Neurotrauma. Methods in Molecular Biology (Clifton, N.J.). 1462: 89-100. PMID 27604714 DOI: 10.1007/978-1-4939-3816-2_6  0.296
2019 Mondello S, Hasan A, Shear DA. Editorial: Developing Successful Neuroprotective Treatments for TBI: Translational Approaches, Novel Directions, Opportunities and Challenges. Frontiers in Neurology. 10: 1326. PMID 31920946 DOI: 10.3389/Fneur.2019.01326  0.29
2015 Boutté AM, Deng-Bryant Y, Johnson D, Tortella FC, Dave JR, Shear DA, Schmid KE. Serum Glial Fibrillary Acidic Protein Predicts Tissue Glial Fibrillary Acidic Protein Break-Down Products and Therapeutic Efficacy after Penetrating Ballistic-Like Brain Injury. Journal of Neurotrauma. PMID 25789543 DOI: 10.1089/neu.2014.3672  0.287
2019 Boutté AM, Thangavelu B, LaValle CR, Nemes J, Gilsdorf J, Shear DA, Kamimori GH. Brain-related proteins as serum biomarkers of acute, subconcussive blast overpressure exposure: A cohort study of military personnel. Plos One. 14: e0221036. PMID 31408492 DOI: 10.1371/Journal.Pone.0221036  0.284
2021 Pandya JD, Leung LY, Hwang HM, Yang X, Deng-Bryant Y, Shear DA. Time-course Evaluation of Brain Regional Mitochondrial Bioenergetics in a Preclinical Model of Severe Penetrating Traumatic Brain Injury. Journal of Neurotrauma. PMID 33544034 DOI: 10.1089/neu.2020.7379  0.284
2020 Bailey ZS, Leung LY, Yang X, Cardiff K, Gilsdorf J, Shear D, Kochanek PM. Pre-Hospital Whole Blood Resuscitation Reduces Fluid Requirement While Maintaining Critical Physiology in a Model of Penetrating Traumatic Brain Injury and Hemorrhage: Implications on Resource-Limited Combat Casualty Care. Shock (Augusta, Ga.). PMID 32925600 DOI: 10.1097/Shk.0000000000001662  0.284
2023 Govindarajulu M, Patel MY, Wilder DM, Krishnan J, LaValle C, Pandya JD, Shear DA, Hefeneider SH, Long JB, Arun P. Upregulation of multiple toll-like receptors in ferret brain after blast exposure: Potential targets for treatment. Neuroscience Letters. 810: 137364. PMID 37391063 DOI: 10.1016/j.neulet.2023.137364  0.274
2021 Li X, Pierre K, Yang Z, Nguyen L, Johnson G, Venetucci J, Torres I, Lucke-Wold B, Shi Y, Boutte A, Shear D, Leung LY, Wang KKW. Blood-Based Brain and Global Biomarker Changes after Combined Hypoxemia and Hemorrhagic Shock in a Rat Model of Penetrating Ballistic-Like Brain Injury. Neurotrauma Reports. 2: 370-380. PMID 34901937 DOI: 10.1089/neur.2021.0006  0.271
2024 Pandya JD, Musyaju S, Modi HR, Okada-Rising SL, Bailey ZS, Scultetus AH, Shear DA. Intranasal delivery of mitochondria targeted neuroprotective compounds for traumatic brain injury: screening based on pharmacological and physiological properties. Journal of Translational Medicine. 22: 167. PMID 38365798 DOI: 10.1186/s12967-024-04908-2  0.27
2023 Pandya JD, Musyaju S, Modi HR, Cao Y, Flerlage WJ, Huynh L, Kociuba B, Visavadiya NP, Kobeissy F, Wang K, Gilsdorf JS, Scultetus AH, Shear DA. Comprehensive evaluation of mitochondrial redox profile, calcium dynamics, membrane integrity and apoptosis markers in a preclinical model of severe penetrating traumatic brain injury. Free Radical Biology & Medicine. 198: 44-58. PMID 36758906 DOI: 10.1016/j.freeradbiomed.2023.02.001  0.257
2021 Zusman BE, Dixon CE, Jha RM, Vagni V, Henchir J, Carlson SW, Janesko-Feldman K, Bailey Z, Shear DA, Gilsdorf J, Kochanek PM. Choice of Whole Blood versus Lactated Ringers Resuscitation Modifies the Relationship Between Blood Pressure Target and Functional Outcome after Traumatic Brain Injury Plus Hemorrhagic Shock in Mice. Journal of Neurotrauma. PMID 34269621 DOI: 10.1089/neu.2021.0157  0.25
2020 Thangavelu B, Kamimori GH, Gilsdorf JS, Shear DA, Boutté AM. Dataset of Rat and Human Serum Proteomes Derived from Differential Depletion Strategies prior to Mass Spectrometry. Data in Brief. 30: 105657. PMID 32426430 DOI: 10.1016/J.Dib.2020.105657  0.233
2020 Shakkour Z, Habashy KJ, Berro M, Takkoush S, Abdelhady S, Koleilat N, Eid AH, Zibara K, Obeid M, Shear D, Mondello S, Wang KK, Kobeissy F. Drug Repurposing in Neurological Disorders: Implications for Neurotherapy in Traumatic Brain Injury. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 1073858420961078. PMID 33089741 DOI: 10.1177/1073858420961078  0.224
2024 Kobeissy F, Arja RD, Munoz JC, Shear DA, Gilsdorf J, Zhu J, Yadikar H, Haskins W, Tyndall JA, Wang KK. The game changer: UCH-L1 and GFAP-based blood test as the first marketed in vitro diagnostic test for mild traumatic brain injury. Expert Review of Molecular Diagnostics. 1-11. PMID 38275158 DOI: 10.1080/14737159.2024.2306876  0.218
2023 Musyaju S, Modi HR, Flerlage WJ, Scultetus AH, Shear DA, Pandya JD. Revert total protein normalization method offers a reliable loading control for mitochondrial samples following TBI. Analytical Biochemistry. 680: 115301. PMID 37673410 DOI: 10.1016/j.ab.2023.115301  0.206
2021 Mountney A, Blaze J, Wang Z, Umali M, Flerlage WJ, Dougherty J, Ge Y, Shear D, Haghighi F. Penetrating Ballistic Brain Injury Produces Acute Alterations in Sleep and Circadian-Related Genes in the Rodent Cortex: A Preliminary Study. Frontiers in Neurology. 12: 745330. PMID 34777213 DOI: 10.3389/fneur.2021.745330  0.191
2019 Haghighi F, Ge Y, Wang Z, Mendelev N, Choi I(, Vitale A, Wilson C, Nemes J, LaValle C, Kamimori G, Shear D, Boutte A, Carr W. 0012 Molecular Correlates of Operational Blast and Associated Sleep Disturbances Sleep. 42: A5-A5. DOI: 10.1093/Sleep/Zsz067.011  0.179
2022 Timmers I, López-Solà M, Heathcote LC, Heirich M, Rush GQ, Shear D, Borsook D, Simons LE. Amygdala functional connectivity mediates the association between catastrophizing and threat-safety learning in youth with chronic pain. Pain. 163: 719-728. PMID 35302974 DOI: 10.1097/j.pain.0000000000002410  0.133
2024 Modi HR, Musyaju S, Ratcliffe M, Shear DA, Scultetus AH, Pandya JD. Mitochondria-Targeted Antioxidant Therapeutics for Traumatic Brain Injury. Antioxidants (Basel, Switzerland). 13. PMID 38539837 DOI: 10.3390/antiox13030303  0.12
2019 Lown EA, Banerjee A, Vittinghoff E, Dvorak CC, Hartogensis W, Melton A, Mangurian C, Hu H, Shear D, Adcock R, Morgan M, Golden C, Hecht FM. Acupressure to Reduce Treatment-Related Symptoms for Children With Cancer and Recipients of Hematopoietic Stem Cell Transplant: Protocol for a Randomized Controlled Trial. Global Advances in Health and Medicine. 8: 2164956119870444. PMID 31453017 DOI: 10.1177/2164956119870444  0.079
2022 Shear D, Harrison LE, O'Brien S, Khazendar Z, Lyons S, Morgan JJ, Chan SK, Feinstein AB, Simons LE. Rapid Transition to Virtual Assessment and Treatment in an Interdisciplinary Randomized Clinical Trial for Youth With Chronic Pain: Adaptations and Implications for Future Trials. The Clinical Journal of Pain. 38: 459-469. PMID 35686576 DOI: 10.1097/AJP.0000000000001040  0.073
2020 Richardson PA, Harrison LE, Heathcote LC, Rush G, Shear D, Lalloo C, Hood K, Wicksell RK, Stinson J, Simons LE. mHealth for Pediatric Chronic Pain: State of the Art and Future Directions. Expert Review of Neurotherapeutics. PMID 32881587 DOI: 10.1080/14737175.2020.1819792  0.066
2019 Hu H, Shear D, Thakkar R, Thompson-Lastad A, Pinderhughes H, Hecht FM, Lown EA. Acupressure and Therapeutic Touch in Childhood Cancer to Promote Subjective and Intersubjective Experiences of Well-being During Curative Treatment. Global Advances in Health and Medicine. 8: 2164956119880143. PMID 31632842 DOI: 10.1177/2164956119880143  0.063
2007 Perlis RH, Beasley CM, Wines JD, Tamura RN, Cusin C, Shear D, Amsterdam J, Quitkin F, Strong RE, Rosenbaum JF, Fava M. Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes. Psychotherapy and Psychosomatics. 76: 40-6. PMID 17170562 DOI: 10.1159/000096363  0.036
2000 Mulholland GW, Johnsson EL, Fernandez MG, Shear DA. Design and testing of a new smoke concentration meter Fire and Materials. 24: 231-243. DOI: 10.1002/1099-1018(200009/10)24:5<231::AID-FAM743>3.0.CO;2-N  0.035
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