Year |
Citation |
Score |
2020 |
Na ES, Lam DD, Yokosawa E, Adams JM, Olson DP, Low MJ. Decreased sensitivity to the anorectic effects of leptin in mice that lack a Pomc-specific neural enhancer. Plos One. 15: e0244793. PMID 33382813 DOI: 10.1371/journal.pone.0244793 |
0.543 |
|
2017 |
Heisler LK, Lam DD. An appetite for life: brain regulation of hunger and satiety. Current Opinion in Pharmacology. 37: 100-106. PMID 29107871 DOI: 10.1016/J.Coph.2017.09.002 |
0.696 |
|
2016 |
Burke LK, Doslikova B, D'Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, et al. Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons. Molecular Metabolism. 5: 245-52. PMID 26977396 DOI: 10.1016/J.Molmet.2016.01.005 |
0.725 |
|
2016 |
Burke LK, Doslikova B, D'Agostino G, Greenwald-Yarnell M, Georgescu T, Chianese R, Martinez de Morentin PB, Ogunnowo-Bada E, Cansell C, Valencia-Torres L, Garfield AS, Apergis-Schoute J, Lam DD, Speakman JR, Rubinstein M, et al. Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons Molecular Metabolism. 5: 245-252. DOI: 10.1016/j.molmet.2016.01.005 |
0.722 |
|
2015 |
Chhabra KH, Adams JM, Fagel B, Lam DD, Qi N, Rubinstein M, Low MJ. Hypothalamic POMC-deficiency improves glucose tolerance despite insulin resistance by increasing glycosuria. Diabetes. PMID 26467632 DOI: 10.2337/Db15-0804 |
0.632 |
|
2015 |
Lam DD, de Souza FS, Nasif S, Yamashita M, López-Leal R, Otero-Corchon V, Meece K, Sampath H, Mercer AJ, Wardlaw SL, Rubinstein M, Low MJ. Partially redundant enhancers cooperatively maintain Mammalian pomc expression above a critical functional threshold. Plos Genetics. 11: e1004935. PMID 25671638 DOI: 10.1371/Journal.Pgen.1004935 |
0.727 |
|
2015 |
Lam DD, Attard CA, Mercer AJ, Myers MG, Rubinstein M, Low MJ. Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism. Endocrinology. 156: 1292-302. PMID 25594696 DOI: 10.1210/En.2014-1373 |
0.785 |
|
2012 |
Osundiji MA, Lam DD, Shaw J, Yueh CY, Markkula SP, Hurst P, Colliva C, Roda A, Heisler LK, Evans ML. Brain glucose sensors play a significant role in the regulation of pancreatic glucose-stimulated insulin secretion. Diabetes. 61: 321-8. PMID 22210318 DOI: 10.2337/Db11-1050 |
0.608 |
|
2011 |
Lam DD, Leinninger GM, Louis GW, Garfield AS, Marston OJ, Leshan RL, Scheller EL, Christensen L, Donato J, Xia J, Evans ML, Elias C, Dalley JW, Burdakov DI, Myers MG, et al. Leptin does not directly affect CNS serotonin neurons to influence appetite. Cell Metabolism. 13: 584-91. PMID 21531340 DOI: 10.1016/J.Cmet.2011.03.016 |
0.662 |
|
2011 |
Zhou L, Yueh CY, Lam DD, Shaw J, Osundiji M, Garfield AS, Evans M, Heisler LK. Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons. Behavioural Brain Research. 222: 274-8. PMID 21440571 DOI: 10.1016/J.Bbr.2011.03.043 |
0.686 |
|
2010 |
Lam DD, Garfield AS, Marston OJ, Shaw J, Heisler LK. Brain serotonin system in the coordination of food intake and body weight. Pharmacology, Biochemistry, and Behavior. 97: 84-91. PMID 20837046 DOI: 10.1016/J.Pbb.2010.09.003 |
0.648 |
|
2010 |
Przydzial MJ, Garfield AS, Lam DD, Moore SP, Evans ML, Heisler LK. Nutritional state influences Nociceptin/Orphanin FQ peptide receptor expression in the dorsal raphe nucleus. Behavioural Brain Research. 206: 313-7. PMID 19765615 DOI: 10.1016/J.Bbr.2009.09.017 |
0.642 |
|
2010 |
Heisler L, Lam D. S.12.05 5-HT2C receptor ligands in the treatment of obesity and type 2 diabetes European Neuropsychopharmacology. 20: S182. DOI: 10.1016/S0924-977X(10)70171-1 |
0.625 |
|
2009 |
Garfield AS, Lam DD, Marston OJ, Przydzial MJ, Heisler LK. Role of central melanocortin pathways in energy homeostasis. Trends in Endocrinology and Metabolism: Tem. 20: 203-15. PMID 19541496 DOI: 10.1016/J.Tem.2009.02.002 |
0.72 |
|
2009 |
Lam DD, Zhou L, Vegge A, Xiu PY, Christensen BT, Osundiji MA, Yueh CY, Evans ML, Heisler LK. Distribution and neurochemical characterization of neurons within the nucleus of the solitary tract responsive to serotonin agonist-induced hypophagia. Behavioural Brain Research. 196: 139-43. PMID 18762217 DOI: 10.1016/J.Bbr.2008.07.039 |
0.693 |
|
2008 |
Kumar KG, Trevaskis JL, Lam DD, Sutton GM, Koza RA, Chouljenko VN, Kousoulas KG, Rogers PM, Kesterson RA, Thearle M, Ferrante AW, Mynatt RL, Burris TP, Dong JZ, Halem HA, et al. Identification of adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metabolism. 8: 468-81. PMID 19041763 DOI: 10.1016/J.Cmet.2008.10.011 |
0.703 |
|
2008 |
Lam DD, Przydzial MJ, Ridley SH, Yeo GS, Rochford JJ, O'Rahilly S, Heisler LK. Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors. Endocrinology. 149: 1323-8. PMID 18039773 DOI: 10.1210/En.2007-1321 |
0.687 |
|
2007 |
Zhou L, Sutton GM, Rochford JJ, Semple RK, Lam DD, Oksanen LJ, Thornton-Jones ZD, Clifton PG, Yueh CY, Evans ML, McCrimmon RJ, Elmquist JK, Butler AA, Heisler LK. Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. Cell Metabolism. 6: 398-405. PMID 17983585 DOI: 10.1016/J.Cmet.2007.10.008 |
0.708 |
|
2007 |
Lam DD, Farooqi IS, Heisler LK. Melanocortin receptors as targets in the treatment of obesity. Current Topics in Medicinal Chemistry. 7: 1085-1097. PMID 17584129 DOI: 10.2174/156802607780906564 |
0.705 |
|
2007 |
Lam DD, Heisler LK. Serotonin and energy balance: molecular mechanisms and implications for type 2 diabetes. Expert Reviews in Molecular Medicine. 9: 1-24. PMID 17316471 DOI: 10.1017/S1462399407000245 |
0.711 |
|
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