Eric J. Nestler - Publications

Affiliations: 
Neuroscience Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Psychiatry
Website:
http://www.mountsinai.org/profiles/eric-j-nestler

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Year Citation  Score
2019 Ribeiro EA, Nectow AR, Pomeranz LE, Ekstrand MI, Koo JW, Nestler EJ. Viral labeling of neurons synaptically connected to nucleus accumbens somatostatin interneurons. Plos One. 14: e0213476. PMID 30845266 DOI: 10.1371/journal.pone.0213476  0.92
2018 Anderson EM, Sun H, Guzman D, Taniguchi M, Cowan CW, Maze I, Nestler EJ, Self DW. Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30587852 DOI: 10.1038/s41386-018-0305-4  1
2018 Cates HM, Bagot RC, Heller EA, Purushothaman I, Lardner CK, Walker DM, Peña CJ, Neve RL, Shen L, Nestler EJ. A novel role for E2F3b in regulating cocaine action in the prefrontal cortex. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30552390 DOI: 10.1038/s41386-018-0296-1  0.92
2018 Tsankova N, Renthal W, Kumar A, Nestler EJ. Author Correction: Epigenetic regulation in psychiatric disorders. Nature Reviews. Neuroscience. PMID 30546104 DOI: 10.1038/s41583-018-0089-x  1
2018 Jiang C, Lin WJ, Labonté B, Tamminga CA, Turecki G, Nestler EJ, Russo SJ, Salton SR. VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30504797 DOI: 10.1038/s41386-018-0277-4  1
2018 Tan A, Costi S, Morris LS, Van Dam NT, Kautz M, Whitton AE, Friedman AK, Collins KA, Ahle G, Chadha N, Do B, Pizzagalli DA, Iosifescu DV, Nestler EJ, Han MH, et al. Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Molecular Psychiatry. PMID 30385872 DOI: 10.1038/s41380-018-0283-2  0.92
2018 Zhang H, Chaudhury D, Nectow AR, Friedman AK, Zhang S, Juarez B, Liu H, Pfau ML, Aleyasin H, Jiang C, Crumiller M, Calipari ES, Ku SM, Morel C, Tzavaras N, ... ... Nestler EJ, et al. α- and β-Adrenergic Receptor-Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice. Biological Psychiatry. PMID 30336931 DOI: 10.1016/j.biopsych.2018.08.020  1
2018 Hamilton PJ, Lim CJ, Nestler EJ, Heller EA. Stereotaxic Surgery and Viral Delivery of Zinc-Finger Epigenetic Editing Tools in Rodent Brain. Methods in Molecular Biology (Clifton, N.J.). 1867: 229-238. PMID 30155827 DOI: 10.1007/978-1-4939-8799-3_17  0.92
2018 Ribeiro EA, Salery M, Scarpa JR, Calipari ES, Hamilton PJ, Ku SM, Kronman H, Purushothaman I, Juarez B, Heshmati M, Doyle M, Lardner C, Burek D, Strat A, Pirpinias S, ... ... Nestler EJ, et al. Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine. Nature Communications. 9: 3149. PMID 30089879 DOI: 10.1038/s41467-018-05657-9  0.96
2018 Cates HM, Li X, Purushothaman I, Kennedy PJ, Shen L, Shaham Y, Nestler EJ. Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30072726 DOI: 10.1038/s41386-018-0158-x  1
2018 Cahill ME, Browne C, Wang J, Hamilton PJ, Dong Y, Nestler EJ. Withdrawal from repeated morphine administration augments expression of the RhoA network in the nucleus accumbens to control synaptic structure. Journal of Neurochemistry. PMID 30071134 DOI: 10.1111/jnc.14563  0.92
2018 Peña CJ, Nestler EJ. Progress in Epigenetics of Depression. Progress in Molecular Biology and Translational Science. 157: 41-66. PMID 29933956 DOI: 10.1016/bs.pmbts.2017.12.011  0.92
2018 Aleyasin H, Flanigan ME, Golden SA, Takahashi A, Menard C, Pfau ML, Multer J, Pina J, McCabe KA, Bhatti N, Hodes GE, Heshmati M, Neve RL, Nestler EJ, Heller EA, et al. Cell-type-specific role of ΔFosB in nucleus accumbens in modulating inter-male aggression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29891732 DOI: 10.1523/JNEUROSCI.0296-18.2018  1
2018 Mul JD, Soto M, Cahill ME, Ryan RE, Takahashi H, So K, Zheng J, Croote DE, Hirshman MF, la Fleur SE, Nestler EJ, Goodyear LJ. Voluntary wheel running promotes resilience to chronic social defeat stress in mice: a role for nucleus accumbens ΔFosB. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29875450 DOI: 10.1038/s41386-018-0103-z  0.4
2018 Walker DM, Cates HM, Loh YE, Purushothaman I, Ramakrishnan A, Cahill KM, Lardner CK, Godino A, Kronman HG, Rabkin J, Lorsch ZS, Mews P, Doyle MA, Feng J, Labonté B, ... ... Nestler EJ, et al. Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain's Reward Circuitry. Biological Psychiatry. PMID 29861096 DOI: 10.1016/j.biopsych.2018.04.009  1
2018 Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Nestler EJ, et al. Corrigendum: Sex-specific transcriptional signatures in human depression. Nature Medicine. 24: 525. PMID 29634684 DOI: 10.1038/nm0418-525d  0.92
2018 Monteggia LM, Heimer H, Nestler EJ. Meeting Report: Can We Make Animal Models of Human Mental Illness? Biological Psychiatry. PMID 29606372 DOI: 10.1016/j.biopsych.2018.02.010  0.72
2018 Lorsch ZS, Loh YE, Purushothaman I, Walker DM, Parise EM, Salery M, Cahill ME, Hodes GE, Pfau ML, Kronman H, Hamilton PJ, Issler O, Labonté B, Symonds AE, Zucker M, ... ... Nestler EJ, et al. Estrogen receptor α drives pro-resilient transcription in mouse models of depression. Nature Communications. 9: 1116. PMID 29549264 DOI: 10.1038/s41467-018-03567-4  1
2018 Hamilton PJ, Lim CJ, Nestler EJ, Heller EA. Viral Expression of Epigenome Editing Tools in Rodent Brain Using Stereotaxic Surgery Techniques. Methods in Molecular Biology (Clifton, N.J.). 1767: 205-214. PMID 29524136 DOI: 10.1007/978-1-4939-7774-1_10  0.92
2018 Hamilton PJ, Lim CJ, Nestler EJ, Heller EA. Neuroepigenetic Editing. Methods in Molecular Biology (Clifton, N.J.). 1767: 113-136. PMID 29524131 DOI: 10.1007/978-1-4939-7774-1_5  0.92
2018 Hultman R, Ulrich K, Sachs BD, Blount C, Carlson DE, Ndubuizu N, Bagot RC, Parise EM, Vu MT, Gallagher NM, Wang J, Silva AJ, Deisseroth K, Mague SD, Caron MG, ... Nestler EJ, et al. Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability. Cell. PMID 29502969 DOI: 10.1016/j.cell.2018.02.012  0.72
2018 Walker DM, Nestler EJ. Neuroepigenetics and addiction. Handbook of Clinical Neurology. 148: 747-765. PMID 29478612 DOI: 10.1016/B978-0-444-64076-5.00048-X  0.76
2018 Calipari ES, Godino A, Peck EG, Salery M, Mervosh NL, Landry JA, Russo SJ, Hurd YL, Nestler EJ, Kiraly DD. Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine. Nature Communications. 9: 9. PMID 29339724 DOI: 10.1038/s41467-017-01881-x  1
2017 Li X, Carreria MB, Witonsky KR, Zeric T, Lofaro OM, Bossert JM, Zhang J, Surjono F, Richie CT, Harvey BK, Son H, Cowan CW, Nestler EJ, Shaham Y. Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving. Biological Psychiatry. PMID 29397902 DOI: 10.1016/j.biopsych.2017.12.008  0.76
2017 Cates HM, Heller EA, Lardner CK, Purushothaman I, Peña CJ, Walker DM, Cahill ME, Neve RL, Shen L, Bagot RC, Nestler EJ. Transcription Factor E2F3a in Nucleus Accumbens Affects Cocaine Action via Transcription and Alternative Splicing. Biological Psychiatry. PMID 29397901 DOI: 10.1016/j.biopsych.2017.11.027  0.92
2017 Anderson EM, Larson EB, Guzman D, Marie Wissman A, Neve RL, Nestler EJ, Self DW. Overexpression of the histone dimethyltransferase G9a in nucleus accumbens shell increases cocaine self-administration, stress-induced reinstatement, and anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29217682 DOI: 10.1523/JNEUROSCI.1657-17.2017  1
2017 You JC, Muralidharan K, Park JW, Petrof I, Pyfer MS, Corbett BF, LaFrancois JJ, Zheng Y, Zhang X, Mohila CA, Yoshor D, Rissman RA, Nestler EJ, Scharfman HE, Chin J. Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits. Nature Medicine. PMID 29035369 DOI: 10.1038/nm.4413  0.4
2017 Takahashi A, Chung JR, Zhang S, Zhang H, Grossman Y, Aleyasin H, Flanigan ME, Pfau ML, Menard C, Dumitriu D, Hodes GE, McEwen BS, Nestler EJ, Han MH, Russo SJ. Establishment of a repeated social defeat stress model in female mice. Scientific Reports. 7: 12838. PMID 28993631 DOI: 10.1038/s41598-017-12811-8  1
2017 Yu J, Yan Y, Li KL, Wang Y, Huang YH, Urban NN, Nestler EJ, Schlüter OM, Dong Y. Nucleus accumbens feedforward inhibition circuit promotes cocaine self-administration. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973852 DOI: 10.1073/pnas.1707822114  0.52
2017 Nätt D, Barchiesi R, Murad J, Feng J, Nestler EJ, Champagne FA, Thorsell A. Perinatal Malnutrition Leads to Sexually Dimorphic Behavioral Responses with Associated Epigenetic Changes in the Mouse Brain. Scientific Reports. 7: 11082. PMID 28894112 DOI: 10.1038/s41598-017-10803-2  1
2017 Akil H, Gordon J, Hen R, Javitch J, Mayberg H, McEwen B, Meaney MJ, Nestler EJ. Treatment Resistant Depression: A Multi-Scale, Systems Biology Approach. Neuroscience and Biobehavioral Reviews. PMID 28859997 DOI: 10.1016/j.neubiorev.2017.08.019  0.68
2017 Dash S, Balasubramaniam M, Rana T, Godino A, Peck EG, Goodwin JS, Villalta F, Calipari ES, Nestler EJ, Dash C, Pandhare J. Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. Eneuro. 4. PMID 28828398 DOI: 10.1523/ENEURO.0089-17.2017  0.64
2017 Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, ... ... Nestler EJ, et al. Sex-specific transcriptional signatures in human depression. Nature Medicine. PMID 28825715 DOI: 10.1038/nm.4386  0.92
2017 Anderson EM, Wissman AM, Chemplanikal J, Buzin N, Guzman D, Larson EB, Neve RL, Nestler EJ, Cowan CW, Self DW. BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808012 DOI: 10.1073/pnas.1702441114  1
2017 Ribeiro EA, Scarpa JR, Garamszegi SP, Kasarskis A, Mash DC, Nestler EJ. Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder. Scientific Reports. 7: 5412. PMID 28710498 DOI: 10.1038/s41598-017-05720-3  0.8
2017 Corbett BF, You JC, Zhang X, Pyfer MS, Tosi U, Iascone DM, Petrof I, Hazra A, Fu CH, Stephens GS, Ashok AA, Aschmies S, Zhao L, Nestler EJ, Chin J. ΔFosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer's Disease. Cell Reports. 20: 344-355. PMID 28700937 DOI: 10.1016/j.celrep.2017.06.040  0.4
2017 Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, ... ... Nestler EJ, et al. The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain. Nature Genetics. PMID 28671686 DOI: 10.1038/ng.3906  0.88
2017 Peña CJ, Kronman HG, Walker DM, Cates HM, Bagot RC, Purushothaman I, Issler O, Loh YE, Leong T, Kiraly DD, Goodman E, Neve RL, Shen L, Nestler EJ. Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2. Science (New York, N.Y.). 356: 1185-1188. PMID 28619944 DOI: 10.1126/science.aan4491  0.92
2017 Muir J, Lorsch ZS, Ramakrishnan C, Deisseroth K, Nestler EJ, Calipari ES, Bagot RC. In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28589967 DOI: 10.1038/npp.2017.122  0.84
2017 Engmann O, Labonté B, Mitchell A, Bashtrykov P, Calipari ES, Rosenbluh C, Loh YE, Walker DM, Burek D, Hamilton PJ, Issler O, Neve RL, Turecki G, Hurd Y, Chess A, ... ... Nestler EJ, et al. Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2. Biological Psychiatry. PMID 28577753 DOI: 10.1016/j.biopsych.2017.04.013  0.92
2017 Lopez JP, Fiori LM, Cruceanu C, Lin R, Labonte B, Cates HM, Heller EA, Vialou V, Ku SM, Gerald C, Han MH, Foster J, Frey BN, Soares CN, Müller DJ, ... ... Nestler EJ, et al. MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes. Nature Communications. 8: 15497. PMID 28530238 DOI: 10.1038/ncomms15497  1
2017 Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K. Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice. Nature Communications. 8: 15142. PMID 28485378 DOI: 10.1038/ncomms15142  0.72
2017 Hamilton PJ, Burek DJ, Lombroso SI, Neve RL, Robison AJ, Nestler EJ, Heller EA. Cell-Type Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28462942 DOI: 10.1038/npp.2017.88  1
2017 Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Wright KN, Mouzon E, Kabbaj M, Neve R, Turecki G, Shen L, Nestler EJ. Regulation of BAZ1A and Nucleosome Positioning in the Nucleus Accumbens in Response to Cocaine. Neuroscience. PMID 28412501 DOI: 10.1016/j.neuroscience.2017.04.007  1
2017 Han MH, Nestler EJ. Neural Substrates of Depression and Resilience. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 28397115 DOI: 10.1007/s13311-017-0527-x  0.92
2017 Zhang H, Qian YL, Li C, Liu D, Wang L, Wang XY, Liu MJ, Liu H, Zhang S, Guo XY, Yang JX, Ding HL, Koo JW, Mouzon E, Deisseroth K, ... Nestler EJ, et al. Brain-Derived Neurotrophic Factor in the Mesolimbic Reward Circuitry Mediates Nociception in Chronic Neuropathic Pain. Biological Psychiatry. PMID 28390647 DOI: 10.1016/j.biopsych.2017.02.1180  1
2017 Zhao JY, Liang L, Gu X, Li Z, Wu S, Sun L, Atianjoh FE, Feng J, Mo K, Jia S, Lutz BM, Bekker A, Nestler EJ, Tao YX. DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons. Nature Communications. 8: 14712. PMID 28270689 DOI: 10.1038/ncomms14712  1
2017 Sun L, Zhao JY, Gu X, Liang L, Wu S, Mo K, Feng J, Guo W, Zhang J, Bekker A, Zhao X, Nestler EJ, Tao YX. Nerve Injury-Induced Epigenetic Silencing Of Opioid Receptors Controlled By Dnmt3a In Primary Afferent Neurons. Pain. PMID 28267064 DOI: 10.1097/j.pain.0000000000000894  1
2017 Ceglia I, Lee KW, Cahill ME, Graves SM, Dietz D, Surmeier DJ, Nestler EJ, Nairn AC, Greengard P, Kim Y. WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115704 DOI: 10.1073/pnas.1621185114  1
2017 Giannarelli C, Rodriguez DT, Zafar MU, Christoffel D, Vialou V, Peña C, Badimon A, Hodes GF, Mury P, Rabkin J, Alique M, Villa G, Argmann C, Nestler EJ, Russo SJ, et al. Susceptibility to chronic social stress increases plaque progression, vulnerability and platelet activation. Thrombosis and Haemostasis. PMID 28078352 DOI: 10.1160/TH16-10-0817  1
2017 Feng J, Pena CJ, Purushothaman I, Engmann O, Walker D, Brown AN, Issler O, Doyle M, Harrigan E, Mouzon E, Vialou V, Shen L, Dawlaty MM, Jaenisch R, Nestler EJ. Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28074830 DOI: 10.1038/npp.2017.6  1
2017 Calipari ES, Juarez B, Morel C, Walker DM, Cahill ME, Ribeiro E, Roman-Ortiz C, Ramakrishnan C, Deisseroth K, Han MH, Nestler EJ. Dopaminergic dynamics underlying sex-specific cocaine reward. Nature Communications. 8: 13877. PMID 28072417 DOI: 10.1038/ncomms13877  0.92
2017 Hodes GE, Walker DM, Labonté B, Nestler EJ, Russo SJ. Understanding the epigenetic basis of sex differences in depression. Journal of Neuroscience Research. 95: 692-702. PMID 27870456 DOI: 10.1002/jnr.23876  1
2016 Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 1: 300-301. PMID 29560862 DOI: 10.1016/j.bpsc.2016.03.007  0.8
2016 Lepack AE, Bagot RC, Peña CJ, Loh YE, Farrelly LA, Lu Y, Powell SK, Lorsch ZS, Issler O, Cates HM, Tamminga CA, Molina H, Shen L, Nestler EJ, Allis CD, et al. Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791098 DOI: 10.1073/pnas.1608270113  1
2016 Torres-Berrío A, Lopez JP, Bagot RC, Nouel D, Dal Bo G, Cuesta S, Zhu L, Manitt C, Eng C, Cooper HM, Storch KF, Turecki G, Nestler EJ, Flores C. DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218. Biological Psychiatry. PMID 27773352 DOI: 10.1016/j.biopsych.2016.08.017  0.72
2016 Kiraly DD, Walker DM, Calipari ES, Labonte B, Issler O, Pena CJ, Ribeiro EA, Russo SJ, Nestler EJ. Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine. Scientific Reports. 6: 35455. PMID 27752130 DOI: 10.1038/srep35455  1
2016 McHenry JA, Robison CL, Bell GA, Vialou VV, Bolaños-Guzmán CA, Nestler EJ, Hull EM. The role of ΔfosB in the medial preoptic area: Differential effects of mating and cocaine history. Behavioral Neuroscience. 130: 469-78. PMID 27657309 DOI: 10.1037/bne0000160  0.84
2016 Bagot RC, Cates HM, Purushothaman I, Vialou V, Heller EA, Yieh L, LaBonté B, Peña CJ, Shen L, Wittenberg GM, Nestler EJ. Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles. Biological Psychiatry. PMID 27569543 DOI: 10.1016/j.biopsych.2016.06.012  1
2016 Kim HD, Hesterman J, Call T, Magazu S, Keeley E, Armenta K, Kronman H, Neve RL, Nestler EJ, Ferguson D. SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8441-52. PMID 27511015 DOI: 10.1523/JNEUROSCI.0212-16.2016  0.96
2016 Damez-Werno DM, Sun H, Scobie KN, Shao N, Rabkin J, Dias C, Calipari ES, Maze I, Pena CJ, Walker DM, Cahill ME, Chandra R, Gancarz A, Mouzon E, Landry JA, ... ... Nestler EJ, et al. Histone arginine methylation in cocaine action in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. PMID 27506785 DOI: 10.1073/pnas.1605045113  1
2016 Wang T, Santos JH, Feng J, Fargo DC, Shen L, Riadi G, Keeley E, Rosh ZS, Nestler EJ, Woychik RP. A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq. Plos One. 11: e0159028. PMID 27415830 DOI: 10.1371/journal.pone.0159028  1
2016 Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AF, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, ... ... Nestler EJ, et al. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biological Psychiatry. 80: 84-6. PMID 27346079 DOI: 10.1016/j.biopsych.2016.05.004  1
2016 Krystal JH, Abi-Dargham A, Barch DM, Bullmore ET, Carter CS, Geschwind DH, Harrison PJ, Nestler EJ, Stein MB. Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. Biological Psychiatry. 80: 2-3. PMID 27312230 DOI: 10.1016/j.biopsych.2016.03.2103  1
2016 Graziane NM, Sun S, Wright WJ, Jang D, Liu Z, Huang YH, Nestler EJ, Wang YT, Schlüter OM, Dong Y. Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses. Nature Neuroscience. PMID 27239940 DOI: 10.1038/nn.4313  1
2016 Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, ... ... Nestler EJ, et al. Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility. Neuron. PMID 27181059 DOI: 10.1016/j.neuron.2016.04.015  1
2016 Heller EA, Hamilton PJ, Burek DD, Lombroso SI, Peña CJ, Neve RL, Nestler EJ. Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4690-7. PMID 27122028 DOI: 10.1523/JNEUROSCI.0013-16.2016  0.92
2016 Ma YY, Wang X, Huang Y, Marie H, Nestler EJ, Schlüter OM, Dong Y. Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091967 DOI: 10.1073/pnas.1524739113  1
2016 Sun H, Martin JA, Werner CT, Wang ZJ, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Gancarz AM, Mouzon EA, Neve RL, Shen L, Dietz DM, ... Nestler EJ, et al. BAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3954-61. PMID 27053203 DOI: 10.1523/JNEUROSCI.3254-15.2016  1
2016 Silverman NS, Popp S, Vialou V, Astafurov K, Nestler EJ, Dow-Edwards D. Effects of Gaboxadol on the Expression of Cocaine Sensitization in Rats. Experimental and Clinical Psychopharmacology. PMID 26901591 DOI: 10.1037/pha0000069  0.44
2016 Cahill ME, Bagot RC, Gancarz AM, Walker DM, Sun H, Wang ZJ, Heller EA, Feng J, Kennedy PJ, Koo JW, Cates HM, Neve RL, Shen L, Dietz DM, Nestler EJ. Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling. Neuron. 89: 566-82. PMID 26844834 DOI: 10.1016/j.neuron.2016.01.031  1
2016 Calipari ES, Bagot RC, Purushothaman I, Davidson TJ, Yorgason JT, Peña CJ, Walker DM, Pirpinias ST, Guise KG, Ramakrishnan C, Deisseroth K, Nestler EJ. In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831103 DOI: 10.1073/pnas.1521238113  1
2016 Anacker C, Scholz J, O'Donnell KJ, Allemang-Grand R, Diorio J, Bagot RC, Nestler EJ, Hen R, Lerch JP, Meaney MJ. Neuroanatomic Differences Associated With Stress Susceptibility and Resilience. Biological Psychiatry. 79: 840-9. PMID 26422005 DOI: 10.1016/j.biopsych.2015.08.009  0.72
2015 Wook Koo J, Labonté B, Engmann O, Calipari ES, Juarez B, Lorsch Z, Walsh JJ, Friedman AK, Yorgason JT, Han MH, Nestler EJ. Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress-Induced Depressive Behaviors. Biological Psychiatry. PMID 26858215 DOI: 10.1016/j.biopsych.2015.12.009  1
2015 Nestler EJ. Reflections on: "A General Role for Adaptations in G-Proteins and the Cyclic AMP System in Mediating the Chronic Actions of Morphine and Cocaine on Neuronal Function". Brain Research. PMID 26740398 DOI: 10.1016/j.brainres.2015.12.039  1
2015 Hodes GE, Pfau ML, Purushothaman I, Ahn HF, Golden SA, Christoffel DJ, Magida J, Brancato A, Takahashi A, Flanigan ME, Ménard C, Aleyasin H, Koo JW, Lorsch ZS, Feng J, ... ... Nestler EJ, et al. Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 16362-76. PMID 26674863 DOI: 10.1523/JNEUROSCI.1392-15.2015  0.72
2015 Feng J, Wilkinson M, Liu X, Purushothaman I, Ferguson D, Vialou V, Maze I, Shao N, Kennedy P, Koo J, Dias C, Laitman B, Stockman V, LaPlant Q, Cahill ME, ... Nestler EJ, et al. Erratum to: Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens. Genome Biology. 16: 227. PMID 26467768 DOI: 10.1186/s13059-015-0789-8  1
2015 Nestler EJ, Peña CJ, Kundakovic M, Mitchell A, Akbarian S. Epigenetic Basis of Mental Illness. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. PMID 26450593 DOI: 10.1177/1073858415608147  0.92
2015 Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Korb E, Bagot RC, Ahn FH, Cahill ME, Labonté B, Mouzon E, Heller EA, Cates H, ... ... Nestler EJ, et al. ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Nature Medicine. PMID 26390241 DOI: 10.1038/nm.3939  1
2015 Plattner F, Hayashi K, Hernández A, Benavides DR, Tassin TC, Tan C, Day J, Fina MW, Yuen EY, Yan Z, Goldberg MS, Nairn AC, Greengard P, Nestler EJ, Taussig R, et al. The role of ventral striatal cAMP signaling in stress-induced behaviors. Nature Neuroscience. 18: 1094-100. PMID 26192746 DOI: 10.1038/nn.4066  0.72
2015 Khibnik LA, Beaumont M, Doyle M, Heshmati M, Slesinger PA, Nestler EJ, Russo SJ. Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens. Biological Psychiatry. PMID 26164802 DOI: 10.1016/j.biopsych.2015.05.022  1
2015 Vialou V, Thibault M, Kaska S, Cooper S, Gajewski P, Eagle A, Mazei-Robison M, Nestler EJ, Robison AJ. Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress. Neuropharmacology. 99: 28-37. PMID 26164345 DOI: 10.1016/j.neuropharm.2015.07.005  1
2015 Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, ... ... Nestler EJ, et al. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 87: 77-94. PMID 26139371 DOI: 10.1016/j.neuron.2015.06.014  1
2015 Ohnishi YH, Ohnishi YN, Nakamura T, Ohno M, Kennedy PJ, Ohkawa Y, Nishi A, Neve R, Tsuzuki T, Nestler EJ. Correction: PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. Plos One. 10: e0131263. PMID 26110846 DOI: 10.1371/journal.pone.0131263  1
2015 Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, Chaudhury D, Persaud B, Cachope R, Bolaños-Guzmán CA, Cheer JF, Deisseroth K, Han MH, Nestler EJ. Corrigendum: Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature Communications. 6: 7626. PMID 26080619 DOI: 10.1038/ncomms8626  1
2015 Wright KN, Hollis F, Duclot F, Dossat AM, Strong CE, Francis TC, Mercer R, Feng J, Dietz DM, Lobo MK, Nestler EJ, Kabbaj M. Methyl Supplementation Attenuates Cocaine-Seeking Behaviors and Cocaine-Induced c-Fos Activation in a DNA Methylation-Dependent Manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8948-58. PMID 26063926 DOI: 10.1523/JNEUROSCI.5227-14.2015  1
2015 Murgatroyd CA, Peña CJ, Podda G, Nestler EJ, Nephew BC. Early life social stress induced changes in depression and anxiety associated neural pathways which are correlated with impaired maternal care. Neuropeptides. PMID 26049556 DOI: 10.1016/j.npep.2015.05.002  1
2015 Li X, Rubio FJ, Zeric T, Bossert JM, Kambhampati S, Cates HM, Kennedy PJ, Liu QR, Cimbro R, Hope BT, Nestler EJ, Shaham Y. Incubation of methamphetamine craving is associated with selective increases in expression of BDNF and trkb, glutamate receptors, and epigenetic enzymes in cue-activated fos-expressing dorsal striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8232-44. PMID 26019338 DOI: 10.1523/JNEUROSCI.1022-15.2015  1
2015 Massart R, Barnea R, Dikshtein Y, Suderman M, Meir O, Hallett M, Kennedy P, Nestler EJ, Szyf M, Yadid G. Role of DNA methylation in the nucleus accumbens in incubation of cocaine craving. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8042-58. PMID 26019323 DOI: 10.1523/JNEUROSCI.3053-14.2015  1
2015 Ohnishi YH, Ohnishi YN, Nakamura T, Ohno M, Kennedy PJ, Yasuyuki O, Nishi A, Neve R, Tsuzuki T, Nestler EJ. PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens. Plos One. 10: e0126710. PMID 25962134 DOI: 10.1371/journal.pone.0126710  1
2015 Dias C, Dietz D, Mazei-Robison M, Sun H, Damez-Werno D, Ferguson D, Wilkinson M, Magida J, Gao V, Neve R, Nestler EJ. Dishevelled-2 regulates cocaine-induced structural plasticity and Rac1 activity in the nucleus accumbens. Neuroscience Letters. 598: 23-8. PMID 25957559 DOI: 10.1016/j.neulet.2015.05.003  1
2015 Bagot RC, Parise EM, Peña CJ, Zhang HX, Maze I, Chaudhury D, Persaud B, Cachope R, Bolaños-Guzmán CA, Cheer J, Deisseroth K, Han MH, Nestler EJ. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nature Communications. 6: 7062. PMID 25952660 DOI: 10.1038/ncomms8062  1
2015 Covington HE, Maze I, Vialou V, Nestler EJ. Antidepressant action of HDAC inhibition in the prefrontal cortex. Neuroscience. 298: 329-35. PMID 25907440 DOI: 10.1016/j.neuroscience.2015.04.030  1
2015 Feng J, Shao N, Szulwach KE, Vialou V, Huynh J, Zhong C, Le T, Ferguson D, Cahill ME, Li Y, Koo JW, Ribeiro E, Labonte B, Laitman BM, Estey D, ... ... Nestler EJ, et al. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature Neuroscience. 18: 536-44. PMID 25774451 DOI: 10.1038/nn.3976  1
2015 Descalzi G, Ikegami D, Ushijima T, Nestler EJ, Zachariou V, Narita M. Epigenetic mechanisms of chronic pain. Trends in Neurosciences. 38: 237-46. PMID 25765319 DOI: 10.1016/j.tins.2015.02.001  1
2015 Ferguson D, Shao N, Heller E, Feng J, Neve R, Kim HD, Call T, Magazu S, Shen L, Nestler EJ. SIRT1-FOXO3a regulate cocaine actions in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3100-11. PMID 25698746 DOI: 10.1523/JNEUROSCI.4012-14.2015  1
2015 Koo JW, Mazei-Robison MS, LaPlant Q, Egervari G, Braunscheidel KM, Adank DN, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno DM, Ribeiro E, Peña CJ, Walker D, Bagot RC, ... ... Nestler EJ, et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nature Neuroscience. 18: 415-22. PMID 25643298 DOI: 10.1038/nn.3932  1
2015 Walker DM, Cates HM, Heller EA, Nestler EJ. Regulation of chromatin states by drugs of abuse. Current Opinion in Neurobiology. 30: 112-21. PMID 25486626 DOI: 10.1016/j.conb.2014.11.002  1
2015 Nestler EJ. ∆FosB: a transcriptional regulator of stress and antidepressant responses. European Journal of Pharmacology. 753: 66-72. PMID 25446562 DOI: 10.1016/j.ejphar.2014.10.034  1
2015 Ohnishi YN, Ohnishi YH, Vialou V, Mouzon E, LaPlant Q, Nishi A, Nestler EJ. Functional role of the N-terminal domain of ΔFosB in response to stress and drugs of abuse. Neuroscience. 284: 165-70. PMID 25313003 DOI: 10.1016/j.neuroscience.2014.10.002  1
2015 Snyder GL, Vanover KE, Zhu H, Miller DB, O'Callaghan JP, Tomesch J, Li P, Zhang Q, Krishnan V, Hendrick JP, Nestler EJ, Davis RE, Wennogle LP, Mates S. Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission. Psychopharmacology. 232: 605-21. PMID 25120104 DOI: 10.1007/s00213-014-3704-1  1
2015 Heller EA, Kaska S, Fallon B, Ferguson D, Kennedy PJ, Neve RL, Nestler EJ, Mazei-Robison MS. Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area. Journal of Neurochemistry. 132: 243-53. PMID 25099208 DOI: 10.1111/jnc.12925  1
2015 Vialou V, Thibault M, Kaska S, Cooper S, Gajewski P, Eagle A, Mazei-Robison M, Nestler EJ, Robison AJ. Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress Neuropharmacology. 99: 28-37. DOI: 10.1016/j.neuropharm.2015.07.005  1
2015 Khibnik LA, Beaumont M, Doyle M, Heshmati M, Slesinger PA, Nestler EJ, Russo SJ. Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.05.022  1
2014 Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonté B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Peña C, ... ... Nestler EJ, et al. β-catenin mediates stress resilience through Dicer1/microRNA regulation. Nature. 516: 51-5. PMID 25383518 DOI: 10.1038/nature13976  1
2014 Bagot RC, Labonté B, Peña CJ, Nestler EJ. Epigenetic signaling in psychiatric disorders: stress and depression. Dialogues in Clinical Neuroscience. 16: 281-95. PMID 25364280  1
2014 Maze I, Shen L, Zhang B, Garcia BA, Shao N, Mitchell A, Sun H, Akbarian S, Allis CD, Nestler EJ. Analytical tools and current challenges in the modern era of neuroepigenomics. Nature Neuroscience. 17: 1476-90. PMID 25349914 DOI: 10.1038/nn.3816  1
2014 Heller EA, Cates HM, Peña CJ, Sun H, Shao N, Feng J, Golden SA, Herman JP, Walsh JJ, Mazei-Robison M, Ferguson D, Knight S, Gerber MA, Nievera C, Han MH, ... ... Nestler EJ, et al. Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors. Nature Neuroscience. 17: 1720-7. PMID 25347353 DOI: 10.1038/nn.3871  1
2014 Zhang Y, Crofton EJ, Li D, Lobo MK, Fan X, Nestler EJ, Green TA. Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment. Frontiers in Behavioral Neuroscience. 8: 297. PMID 25221490 DOI: 10.3389/fnbeh.2014.00297  1
2014 Feyder M, Södersten E, Santini E, Vialou V, LaPlant Q, Watts EL, Spigolon G, Hansen K, Caboche J, Nestler EJ, Fisone G. A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA-Induced Dyskinesia and ∆FosB Expression. Biological Psychiatry. PMID 25193242 DOI: 10.1016/j.biopsych.2014.07.019  1
2014 Cates HM, Thibault M, Pfau M, Heller E, Eagle A, Gajewski P, Bagot R, Colangelo C, Abbott T, Rudenko G, Neve R, Nestler EJ, Robison AJ. Threonine 149 phosphorylation enhances ΔFosB transcriptional activity to control psychomotor responses to cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11461-9. PMID 25143625 DOI: 10.1523/JNEUROSCI.1611-14.2014  1
2014 Lazenka MF, David BG, Lichtman AH, Nestler EJ, Selley DE, Sim-Selley LJ. Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions. Biochemical Pharmacology. 91: 380-9. PMID 25093286 DOI: 10.1016/j.bcp.2014.07.024  1
2014 Dong Y, Nestler EJ. The neural rejuvenation hypothesis of cocaine addiction. Trends in Pharmacological Sciences. 35: 374-83. PMID 24958329 DOI: 10.1016/j.tips.2014.05.005  1
2014 Koo JW, Lobo MK, Chaudhury D, Labonté B, Friedman A, Heller E, Peña CJ, Han MH, Nestler EJ. Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2646-53. PMID 24853771 DOI: 10.1038/npp.2014.118  1
2014 Nomaru H, Sakumi K, Katogi A, Ohnishi YN, Kajitani K, Tsuchimoto D, Nestler EJ, Nakabeppu Y. Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia. Glia. 62: 1284-98. PMID 24771617 DOI: 10.1002/glia.22680  1
2014 Feng J, Wilkinson M, Liu X, Purushothaman I, Ferguson D, Vialou V, Maze I, Shao N, Kennedy P, Koo J, Dias C, Laitman B, Stockman V, LaPlant Q, Cahill ME, ... Nestler EJ, et al. Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens. Genome Biology. 15: R65. PMID 24758366 DOI: 10.1186/gb-2014-15-4-r65  1
2014 Mazei-Robison MS, Appasani R, Edwards S, Wee S, Taylor SR, Picciotto MR, Koob GF, Nestler EJ. Self-administration of ethanol, cocaine, or nicotine does not decrease the soma size of ventral tegmental area dopamine neurons. Plos One. 9: e95962. PMID 24755634 DOI: 10.1371/journal.pone.0095962  1
2014 Shen L, Shao N, Liu X, Nestler E. ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases. Bmc Genomics. 15: 284. PMID 24735413 DOI: 10.1186/1471-2164-15-284  1
2014 Arango-Lievano M, Schwarz JT, Vernov M, Wilkinson MB, Bradbury K, Feliz A, Marongiu R, Gelfand Y, Warner-Schmidt J, Nestler EJ, Greengard P, Russo SJ, Kaplitt MG. Cell-type specific expression of p11 controls cocaine reward. Biological Psychiatry. 76: 794-801. PMID 24725970 DOI: 10.1016/j.biopsych.2014.02.012  1
2014 Peña CJ, Bagot RC, Labonté B, Nestler EJ. Epigenetic signaling in psychiatric disorders. Journal of Molecular Biology. 426: 3389-412. PMID 24709417 DOI: 10.1016/j.jmb.2014.03.016  1
2014 Sarkar A, Chachra P, Kennedy P, Pena CJ, Desouza LA, Nestler EJ, Vaidya VA. Hippocampal HDAC4 contributes to postnatal fluoxetine-evoked depression-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2221-32. PMID 24663010 DOI: 10.1038/npp.2014.73  1
2014 Geschwind D, Nestler EJ. Neurodegenerative dementias: connecting psychiatry and neurology through a shared neurobiology. Biological Psychiatry. 75: 518-9. PMID 24629667 DOI: 10.1016/j.biopsych.2014.02.007  1
2014 Vialou V, Bagot RC, Cahill ME, Ferguson D, Robison AJ, Dietz DM, Fallon B, Mazei-Robison M, Ku SM, Harrigan E, Winstanley CA, Joshi T, Feng J, Berton O, Nestler EJ. Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of ΔFosB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3878-87. PMID 24623766 DOI: 10.1523/JNEUROSCI.1787-13.2014  1
2014 Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Sillivan SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, ... ... Nestler EJ, et al. G9a influences neuronal subtype specification in striatum. Nature Neuroscience. 17: 533-9. PMID 24584053 DOI: 10.1038/nn.3670  1
2014 Der-Avakian A, Mazei-Robison MS, Kesby JP, Nestler EJ, Markou A. Enduring deficits in brain reward function after chronic social defeat in rats: susceptibility, resilience, and antidepressant response. Biological Psychiatry. 76: 542-9. PMID 24576687 DOI: 10.1016/j.biopsych.2014.01.013  1
2014 Nestler EJ. Epigenetic mechanisms of depression. Jama Psychiatry. 71: 454-6. PMID 24499927 DOI: 10.1001/jamapsychiatry.2013.4291  1
2014 Donahue RJ, Muschamp JW, Russo SJ, Nestler EJ, Carlezon WA. Effects of striatal ΔFosB overexpression and ketamine on social defeat stress-induced anhedonia in mice. Biological Psychiatry. 76: 550-8. PMID 24495460 DOI: 10.1016/j.biopsych.2013.12.014  1
2014 Scobie KN, Damez-Werno D, Sun H, Shao N, Gancarz A, Panganiban CH, Dias C, Koo J, Caiafa P, Kaufman L, Neve RL, Dietz DM, Shen L, Nestler EJ. Essential role of poly(ADP-ribosyl)ation in cocaine action. Proceedings of the National Academy of Sciences of the United States of America. 111: 2005-10. PMID 24449909 DOI: 10.1073/pnas.1319703111  1
2014 Iñiguez SD, Alcantara LF, Warren BL, Riggs LM, Parise EM, Vialou V, Wright KN, Dayrit G, Nieto SJ, Wilkinson MB, Lobo MK, Neve RL, Nestler EJ, Bolaños-Guzmán CA. Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1007-21. PMID 24431458 DOI: 10.1523/JNEUROSCI.5725-12.2014  1
2014 Walsh JJ, Friedman AK, Sun H, Heller EA, Ku SM, Juarez B, Burnham VL, Mazei-Robison MS, Ferguson D, Golden SA, Koo JW, Chaudhury D, Christoffel DJ, Pomeranz L, Friedman JM, ... ... Nestler EJ, et al. Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway. Nature Neuroscience. 17: 27-9. PMID 24270188 DOI: 10.1038/nn.3591  1
2014 Robison AJ, Vialou V, Sun HS, Labonte B, Golden SA, Dias C, Turecki G, Tamminga C, Russo S, Mazei-Robison M, Nestler EJ. Fluoxetine epigenetically alters the CaMKIIα promoter in nucleus accumbens to regulate ΔFosB binding and antidepressant effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1178-86. PMID 24240473 DOI: 10.1038/npp.2013.319  1
2014 Dietz DM, Kennedy PJ, Sun H, Maze I, Gancarz AM, Vialou V, Koo JW, Mouzon E, Ghose S, Tamminga CA, Nestler EJ. ΔFosB induction in prefrontal cortex by antipsychotic drugs is associated with negative behavioral outcomes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 538-44. PMID 24067299 DOI: 10.1038/npp.2013.255  1
2014 Nestler EJ. Epigenetic mechanisms of drug addiction. Neuropharmacology. 76: 259-68. PMID 23643695 DOI: 10.1016/j.neuropharm.2013.04.004  1
2013 Nestler EJ. Cellular basis of memory for addiction. Dialogues in Clinical Neuroscience. 15: 431-43. PMID 24459410  1
2013 Manitt C, Eng C, Pokinko M, Ryan RT, Torres-Berrío A, Lopez JP, Yogendran SV, Daubaras MJ, Grant A, Schmidt ER, Tronche F, Krimpenfort P, Cooper HM, Pasterkamp RJ, Kolb B, ... ... Nestler EJ, et al. dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients. Translational Psychiatry. 3: e338. PMID 24346136 DOI: 10.1038/tp.2013.105  1
2013 Lobo MK, Zaman S, Damez-Werno DM, Koo JW, Bagot RC, DiNieri JA, Nugent A, Finkel E, Chaudhury D, Chandra R, Riberio E, Rabkin J, Mouzon E, Cachope R, Cheer JF, ... ... Nestler EJ, et al. ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18381-95. PMID 24259563 DOI: 10.1523/JNEUROSCI.1875-13.2013  1
2013 Ferguson D, Koo JW, Feng J, Heller E, Rabkin J, Heshmati M, Renthal W, Neve R, Liu X, Shao N, Sartorelli V, Shen L, Nestler EJ. Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16088-98. PMID 24107942 DOI: 10.1523/JNEUROSCI.1284-13.2013  1
2013 Lee BR, Ma YY, Huang YH, Wang X, Otaka M, Ishikawa M, Neumann PA, Graziane NM, Brown TE, Suska A, Guo C, Lobo MK, Sesack SR, Wolf ME, Nestler EJ, et al. Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving. Nature Neuroscience. 16: 1644-51. PMID 24077564 DOI: 10.1038/nn.3533  1
2013 Russo SJ, Nestler EJ. The brain reward circuitry in mood disorders. Nature Reviews. Neuroscience. 14: 609-25. PMID 23942470 DOI: 10.1038/nrn3381  1
2013 Shen L, Choi I, Nestler EJ, Won KJ. Human Transcriptome and Chromatin Modifications: An ENCODE Perspective. Genomics & Informatics. 11: 60-7. PMID 23843771 DOI: 10.5808/GI.2013.11.2.60  0.88
2013 Been LE, Hedges VL, Vialou V, Nestler EJ, Meisel RL. ΔJunD overexpression in the nucleus accumbens prevents sexual reward in female Syrian hamsters. Genes, Brain, and Behavior. 12: 666-72. PMID 23790091 DOI: 10.1111/gbb.12060  1
2013 Shen L, Shao NY, Liu X, Maze I, Feng J, Nestler EJ. diffReps: detecting differential chromatin modification sites from ChIP-seq data with biological replicates. Plos One. 8: e65598. PMID 23762400 DOI: 10.1371/journal.pone.0065598  1
2013 Nestler EJ. Treating the brain deep down: Brain surgery for anorexia nervosa? Nature Medicine. 19: 678-9. PMID 23744148 DOI: 10.1038/nm.3223  1
2013 Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling 4 [corrected] is a crucial modulator of antidepressant drug action in depression and neuropathic pain models. Proceedings of the National Academy of Sciences of the United States of America. 110: 8254-9. PMID 23630294 DOI: 10.1073/pnas.1214696110  1
2013 Thanos PK, Robison L, Nestler EJ, Kim R, Michaelides M, Lobo MK, Volkow ND. Mapping brain metabolic connectivity in awake rats with μPET and optogenetic stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6343-9. PMID 23575833 DOI: 10.1523/JNEUROSCI.4997-12.2013  1
2013 Kurita M, Moreno JL, Holloway T, Kozlenkov A, Mocci G, García-Bea A, Hanks JB, Neve R, Nestler EJ, Russo SJ, González-Maeso J. Repressive epigenetic changes at the mGlu2 promoter in frontal cortex of 5-HT2A knockout mice. Molecular Pharmacology. 83: 1166-75. PMID 23508685 DOI: 10.1124/mol.112.084582  1
2013 Guanghua X, Xinlei W, Quincey L, Nestler EJ, Xie Y. Detection of epigenetic changes using ANOVA with spatially varying coefficients. Statistical Applications in Genetics and Molecular Biology. 12: 189-205. PMID 23502341 DOI: 10.1515/sagmb-2012-0057  1
2013 Kennedy PJ, Feng J, Robison AJ, Maze I, Badimon A, Mouzon E, Chaudhury D, Damez-Werno DM, Haggarty SJ, Han MH, Bassel-Duby R, Olson EN, Nestler EJ. Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation. Nature Neuroscience. 16: 434-40. PMID 23475113 DOI: 10.1038/nn.3354  1
2013 Robison AJ, Vialou V, Mazei-Robison M, Feng J, Kourrich S, Collins M, Wee S, Koob G, Turecki G, Neve R, Thomas M, Nestler EJ. Behavioral and structural responses to chronic cocaine require a feedforward loop involving ΔFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4295-307. PMID 23467346 DOI: 10.1523/JNEUROSCI.5192-12.2013  1
2013 Pitchers KK, Vialou V, Nestler EJ, Laviolette SR, Lehman MN, Coolen LM. Natural and drug rewards act on common neural plasticity mechanisms with ΔFosB as a key mediator. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 3434-42. PMID 23426671 DOI: 10.1523/JNEUROSCI.4881-12.2013  1
2013 Feng J, Nestler EJ. Epigenetic mechanisms of drug addiction. Current Opinion in Neurobiology. 23: 521-8. PMID 23374537 DOI: 10.1016/j.conb.2013.01.001  1
2013 Grueter BA, Robison AJ, Neve RL, Nestler EJ, Malenka RC. ∆FosB differentially modulates nucleus accumbens direct and indirect pathway function. Proceedings of the National Academy of Sciences of the United States of America. 110: 1923-8. PMID 23319622 DOI: 10.1073/pnas.1221742110  1
2013 Greengard P. A conversation with Paul Greengard. Interview by Eric J Nestler. Annual Review of Pharmacology and Toxicology. 53: 1-16. PMID 23294305 DOI: 10.1146/annurev-pharmtox-062712-160347  1
2013 Suri D, Veenit V, Sarkar A, Thiagarajan D, Kumar A, Nestler EJ, Galande S, Vaidya VA. Early stress evokes age-dependent biphasic changes in hippocampal neurogenesis, BDNF expression, and cognition. Biological Psychiatry. 73: 658-66. PMID 23237316 DOI: 10.1016/j.biopsych.2012.10.023  1
2013 Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, ... ... Nestler EJ, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 493: 532-6. PMID 23235832 DOI: 10.1038/nature11713  1
2013 Akbarian S, Nestler EJ. Epigenetic mechanisms in psychiatry. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1-2. PMID 23147478 DOI: 10.1038/npp.2012.185  1
2013 Vialou V, Feng J, Robison AJ, Nestler EJ. Epigenetic mechanisms of depression and antidepressant action. Annual Review of Pharmacology and Toxicology. 53: 59-87. PMID 23020296 DOI: 10.1146/annurev-pharmtox-010611-134540  1
2013 Warren BL, Vialou VF, Iñiguez SD, Alcantara LF, Wright KN, Feng J, Kennedy PJ, Laplant Q, Shen L, Nestler EJ, Bolaños-Guzmán CA. Neurobiological sequelae of witnessing stressful events in adult mice. Biological Psychiatry. 73: 7-14. PMID 22795644 DOI: 10.1016/j.biopsych.2012.06.006  1
2013 Sun H, Kennedy PJ, Nestler EJ. Epigenetics of the depressed brain: role of histone acetylation and methylation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 124-37. PMID 22692567 DOI: 10.1038/npp.2012.73  1
2013 Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling is a crucial modulator of antidepressant drug action in depression and neuropathic pain models(Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 20 (8254-8259)) Proceedings of the National Academy of Sciences of the United States of America. 110: 11660. DOI: 10.1073/pnas.1311399110  1
2013 Sweatt JD, Nestler EJ, Meaney MJ, Akbarian S. Preface Epigenetic Regulation in the Nervous System. ix-ix. DOI: 10.1016/B978-0-12-391494-1.00019-7  1
2013 Meaney MJ, Akbarian S, Nestler EJ, Sweatt JD. Epigenetics. Defining the Frontiers of Genomic Function Epigenetic Regulation in the Nervous System. 341-353. DOI: 10.1016/B978-0-12-391494-1.00014-8  1
2013 Robison AJ, Feng J, Nestler EJ. Drug Addiction and Reward Epigenetic Regulation in the Nervous System. 173-195. DOI: 10.1016/B978-0-12-391494-1.00006-9  1
2013 Sweatt JD, Nestler EJ, Meaney MJ, Akbarian S. An Overview of the Molecular Basis of Epigenetics Epigenetic Regulation in the Nervous System. 3-33. DOI: 10.1016/B978-0-12-391494-1.00001-X  1
2013 Sweatt JD, Nestler EJ, Meaney MJ, Akbarian S. Epigenetic Regulation in the Nervous System Epigenetic Regulation in the Nervous System 1
2012 Nestler EJ. Transcriptional mechanisms of drug addiction. Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology. 10: 136-43. PMID 23430970 DOI: 10.9758/cpn.2012.10.3.136  1
2012 Sun H, Maze I, Dietz DM, Scobie KN, Kennedy PJ, Damez-Werno D, Neve RL, Zachariou V, Shen L, Nestler EJ. Morphine epigenomically regulates behavior through alterations in histone H3 lysine 9 dimethylation in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17454-64. PMID 23197736 DOI: 10.1523/JNEUROSCI.1357-12.2012  1
2012 Liu J, Dietz K, DeLoyht JM, Pedre X, Kelkar D, Kaur J, Vialou V, Lobo MK, Dietz DM, Nestler EJ, Dupree J, Casaccia P. Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nature Neuroscience. 15: 1621-3. PMID 23143512 DOI: 10.1038/nn.3263  1
2012 Russo SJ, Murrough JW, Han MH, Charney DS, Nestler EJ. Neurobiology of resilience. Nature Neuroscience. 15: 1475-84. PMID 23064380 DOI: 10.1038/nn.3234  1
2012 Nestler EJ. Epigenetics: Stress makes its molecular mark. Nature. 490: 171-2. PMID 23060173 DOI: 10.1038/490171a  1
2012 Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Dietz DM, ... ... Nestler EJ, et al. BDNF is a negative modulator of morphine action. Science (New York, N.Y.). 338: 124-8. PMID 23042896 DOI: 10.1126/science.1222265  1
2012 Kurita M, Holloway T, García-Bea A, Kozlenkov A, Friedman AK, Moreno JL, Heshmati M, Golden SA, Kennedy PJ, Takahashi N, Dietz DM, Mocci G, Gabilondo AM, Hanks J, Umali A, ... ... Nestler EJ, et al. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nature Neuroscience. 15: 1245-54. PMID 22864611 DOI: 10.1038/nn.3181  1
2012 Wang Y, Cesena TI, Ohnishi Y, Burger-Caplan R, Lam V, Kirchhoff PD, Larsen SD, Larsen MJ, Nestler EJ, Rudenko G. Small molecule screening identifies regulators of the transcription factor ΔFosB. Acs Chemical Neuroscience. 3: 546-56. PMID 22860224 DOI: 10.1021/cn3000235  1
2012 Damez-Werno D, LaPlant Q, Sun H, Scobie KN, Dietz DM, Walker IM, Koo JW, Vialou VF, Mouzon E, Russo SJ, Nestler EJ. Drug experience epigenetically primes Fosb gene inducibility in rat nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10267-72. PMID 22836260 DOI: 10.1523/JNEUROSCI.1290-12.2012  1
2012 Mazei-Robison MS, Nestler EJ. Opiate-induced molecular and cellular plasticity of ventral tegmental area and locus coeruleus catecholamine neurons. Cold Spring Harbor Perspectives in Medicine. 2: a012070. PMID 22762025 DOI: 10.1101/cshperspect.a012070  1
2012 Cunningham JT, Knight WD, Mifflin SW, Nestler EJ. An Essential role for DeltaFosB in the median preoptic nucleus in the sustained hypertensive effects of chronic intermittent hypoxia. Hypertension. 60: 179-87. PMID 22689746 DOI: 10.1161/HYPERTENSIONAHA.112.193789  1
2012 Tomasiewicz HC, Jacobs MM, Wilkinson MB, Wilson SP, Nestler EJ, Hurd YL. Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability. Biological Psychiatry. 72: 803-10. PMID 22683090 DOI: 10.1016/j.biopsych.2012.04.026  1
2012 Nestler EJ, Krystal JH. Planning the new national institute on substance use and addiction disorders. Biological Psychiatry. 72: 166-7. PMID 22683089 DOI: 10.1016/j.biopsych.2012.05.011  1
2012 Vialou V, Feng J, Robison AJ, Ku SM, Ferguson D, Scobie KN, Mazei-Robison MS, Mouzon E, Nestler EJ. Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7577-84. PMID 22649236 DOI: 10.1523/JNEUROSCI.1381-12.2012  1
2012 Cunningham JT, Nedungadi TP, Walch JD, Nestler EJ, Gottlieb HB. ΔFosB in the supraoptic nucleus contributes to hyponatremia in rats with cirrhosis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 303: R177-85. PMID 22621966 DOI: 10.1152/ajpregu.00142.2012  1
2012 Dumitriu D, Laplant Q, Grossman YS, Dias C, Janssen WG, Russo SJ, Morrison JH, Nestler EJ. Subregional, dendritic compartment, and spine subtype specificity in cocaine regulation of dendritic spines in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6957-66. PMID 22593064 DOI: 10.1523/JNEUROSCI.5718-11.2012  1
2012 Dietz DM, Sun H, Lobo MK, Cahill ME, Chadwick B, Gao V, Koo JW, Mazei-Robison MS, Dias C, Maze I, Damez-Werno D, Dietz KC, Scobie KN, Ferguson D, Christoffel D, ... ... Nestler EJ, et al. Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons. Nature Neuroscience. 15: 891-6. PMID 22522400 DOI: 10.1038/nn.3094  1
2012 Tronson NC, Wiseman SL, Neve RL, Nestler EJ, Olausson P, Taylor JR. Distinctive roles for amygdalar CREB in reconsolidation and extinction of fear memory. Learning & Memory (Cold Spring Harbor, N.Y.). 19: 178-81. PMID 22505719 DOI: 10.1101/lm.025783.112  1
2012 Rowe GC, Vialou V, Sato K, Saito H, Yin M, Green TA, Lotinun S, Kveiborg M, Horne WC, Nestler EJ, Baron R. Energy expenditure and bone formation share a common sensitivity to AP-1 transcription in the hypothalamus. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1649-58. PMID 22461201 DOI: 10.1002/jbmr.1618  1
2012 Lobo MK, Nestler EJ, Covington HE. Potential utility of optogenetics in the study of depression. Biological Psychiatry. 71: 1068-74. PMID 22322104 DOI: 10.1016/j.biopsych.2011.12.026  1
2012 Dietz DM, Nestler EJ. From father to offspring: paternal transmission of depressive-like behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 311-2. PMID 22157877 DOI: 10.1038/npp.2011.167  1
2012 Muschamp JW, Nemeth CL, Robison AJ, Nestler EJ, Carlezon WA. ΔFosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid receptor agonist U50488. Biological Psychiatry. 71: 44-50. PMID 21962331 DOI: 10.1016/j.biopsych.2011.08.011  1
2012 Pittenger C, Nestler EJ, Duman RS. Cyclic Nucleotides in the Nervous System Basic Neurochemistry. 423-441. DOI: 10.1016/B978-0-12-374947-5.00022-5  1
2012 Zachariou V, Duman RS, Nestler EJ. G Proteins Basic Neurochemistry. 411-422. DOI: 10.1016/B978-0-12-374947-5.00021-3  1
2011 Nestler EJ. Hidden switches in the mind. Scientific American. 305: 76-83. PMID 22214133 DOI: 10.1038/scientificamerican1211-76  1
2011 Mazei-Robison MS, Koo JW, Friedman AK, Lansink CS, Robison AJ, Vinish M, Krishnan V, Kim S, Siuta MA, Galli A, Niswender KD, Appasani R, Horvath MC, Neve RL, Worley PF, ... ... Nestler EJ, et al. Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons. Neuron. 72: 977-90. PMID 22196333 DOI: 10.1016/j.neuron.2011.10.012  1
2011 Larson EB, Graham DL, Arzaga RR, Buzin N, Webb J, Green TA, Bass CE, Neve RL, Terwilliger EF, Nestler EJ, Self DW. Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16447-57. PMID 22072694 DOI: 10.1523/JNEUROSCI.3070-11.2011  1
2011 Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, et al. Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences. 1236: 30-43. PMID 22032400 DOI: 10.1111/j.1749-6632.2011.06216.x  1
2011 Robison AJ, Nestler EJ. Transcriptional and epigenetic mechanisms of addiction. Nature Reviews. Neuroscience. 12: 623-37. PMID 21989194 DOI: 10.1038/nrn3111  1
2011 Sim-Selley LJ, Cassidy MP, Sparta A, Zachariou V, Nestler EJ, Selley DE. Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens. Neuropharmacology. 61: 1470-6. PMID 21907220 DOI: 10.1016/j.neuropharm.2011.08.046  1
2011 Covington HE, Maze I, Sun H, Bomze HM, DeMaio KD, Wu EY, Dietz DM, Lobo MK, Ghose S, Mouzon E, Neve RL, Tamminga CA, Nestler EJ. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron. 71: 656-70. PMID 21867882 DOI: 10.1016/j.neuron.2011.06.007  1
2011 Lobo MK, Nestler EJ. The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons. Frontiers in Neuroanatomy. 5: 41. PMID 21811439 DOI: 10.3389/fnana.2011.00041  1
2011 Wilkinson MB, Dias C, Magida J, Mazei-Robison M, Lobo M, Kennedy P, Dietz D, Covington H, Russo S, Neve R, Ghose S, Tamminga C, Nestler EJ. A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9084-92. PMID 21697359 DOI: 10.1523/JNEUROSCI.0039-11.2011  1
2011 Ohnishi YN, Ohnishi YH, Hokama M, Nomaru H, Yamazaki K, Tominaga Y, Sakumi K, Nestler EJ, Nakabeppu Y. FosB is essential for the enhancement of stress tolerance and antagonizes locomotor sensitization by ΔFosB. Biological Psychiatry. 70: 487-95. PMID 21679928 DOI: 10.1016/j.biopsych.2011.04.021  1
2011 Dietz DM, Laplant Q, Watts EL, Hodes GE, Russo SJ, Feng J, Oosting RS, Vialou V, Nestler EJ. Paternal transmission of stress-induced pathologies. Biological Psychiatry. 70: 408-14. PMID 21679926 DOI: 10.1016/j.biopsych.2011.05.005  1
2011 Brown TE, Lee BR, Mu P, Ferguson D, Dietz D, Ohnishi YN, Lin Y, Suska A, Ishikawa M, Huang YH, Shen H, Kalivas PW, Sorg BA, Zukin RS, Nestler EJ, et al. A silent synapse-based mechanism for cocaine-induced locomotor sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8163-74. PMID 21632938 DOI: 10.1523/JNEUROSCI.0016-11.2011  1
2011 Choi KH, Edwards S, Graham DL, Larson EB, Whisler KN, Simmons D, Friedman AK, Walsh JJ, Rahman Z, Monteggia LM, Eisch AJ, Neve RL, Nestler EJ, Han MH, Self DW. Reinforcement-related regulation of AMPA glutamate receptor subunits in the ventral tegmental area enhances motivation for cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7927-37. PMID 21613507 DOI: 10.1523/JNEUROSCI.6014-10.2011  1
2011 Knoll AT, Muschamp JW, Sillivan SE, Ferguson D, Dietz DM, Meloni EG, Carroll FI, Nestler EJ, Konradi C, Carlezon WA. Kappa opioid receptor signaling in the basolateral amygdala regulates conditioned fear and anxiety in rats. Biological Psychiatry. 70: 425-33. PMID 21531393 DOI: 10.1016/j.biopsych.2011.03.017  1
2011 Scott MM, Marcus JN, Pettersen A, Birnbaum SG, Mochizuki T, Scammell TE, Nestler EJ, Elmquist JK, Lutter M. Hcrtr1 and 2 signaling differentially regulates depression-like behaviors. Behavioural Brain Research. 222: 289-94. PMID 21377495 DOI: 10.1016/j.bbr.2011.02.044  1
2011 Covington HE, Vialou VF, LaPlant Q, Ohnishi YN, Nestler EJ. Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition. Neuroscience Letters. 493: 122-6. PMID 21335060 DOI: 10.1016/j.neulet.2011.02.022  1
2011 Maze I, Feng J, Wilkinson MB, Sun H, Shen L, Nestler EJ. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 108: 3035-40. PMID 21300862 DOI: 10.1073/pnas.1015483108  1
2011 Maze I, Nestler EJ. The epigenetic landscape of addiction. Annals of the New York Academy of Sciences. 1216: 99-113. PMID 21272014 DOI: 10.1111/j.1749-6632.2010.05893.x  1
2011 Krishnan V, Nestler EJ. Animal models of depression: molecular perspectives. Current Topics in Behavioral Neurosciences. 7: 121-47. PMID 21225412 DOI: 10.1007/7854_2010_108  1
2011 Vialou V, Cui H, Perello M, Mahgoub M, Yu HG, Rush AJ, Pranav H, Jung S, Yangisawa M, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A role for ΔFosB in calorie restriction-induced metabolic changes. Biological Psychiatry. 70: 204-7. PMID 21215388 DOI: 10.1016/j.biopsych.2010.11.027  1
2011 Berger AK, Green T, Siegel SJ, Nestler EJ, Hammer RP. cAMP response element binding protein phosphorylation in nucleus accumbens underlies sustained recovery of sensorimotor gating following repeated D₂-like receptor agonist treatment in rats. Biological Psychiatry. 69: 288-94. PMID 21035786 DOI: 10.1016/j.biopsych.2010.08.032  1
2011 LaPlant Q, Nestler EJ. CRACKing the histone code: cocaine's effects on chromatin structure and function. Hormones and Behavior. 59: 321-30. PMID 20594965 DOI: 10.1016/j.yhbeh.2010.05.015  1
2010 Cao JL, Covington HE, Friedman AK, Wilkinson MB, Walsh JJ, Cooper DC, Nestler EJ, Han MH. Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16453-8. PMID 21147984 DOI: 10.1523/JNEUROSCI.3177-10.2010  1
2010 Covington HE, Lobo MK, Maze I, Vialou V, Hyman JM, Zaman S, LaPlant Q, Mouzon E, Ghose S, Tamminga CA, Neve RL, Deisseroth K, Nestler EJ. Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16082-90. PMID 21123555 DOI: 10.1523/JNEUROSCI.1731-10.2010  1
2010 Vialou V, Maze I, Renthal W, LaPlant QC, Watts EL, Mouzon E, Ghose S, Tamminga CA, Nestler EJ. Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14585-92. PMID 20980616 DOI: 10.1523/JNEUROSCI.2496-10.2010  1
2010 Lobo MK, Covington HE, Chaudhury D, Friedman AK, Sun H, Damez-Werno D, Dietz DM, Zaman S, Koo JW, Kennedy PJ, Mouzon E, Mogri M, Neve RL, Deisseroth K, Han MH, ... Nestler EJ, et al. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). 330: 385-90. PMID 20947769 DOI: 10.1126/science.1188472  1
2010 Nestler EJ, Hyman SE. Animal models of neuropsychiatric disorders. Nature Neuroscience. 13: 1161-9. PMID 20877280 DOI: 10.1038/nn.2647  1
2010 Krishnan V, Nestler EJ. Linking molecules to mood: new insight into the biology of depression. The American Journal of Psychiatry. 167: 1305-20. PMID 20843874 DOI: 10.1176/appi.ajp.2009.10030434  1
2010 Cao JL, Vialou VF, Lobo MK, Robison AJ, Neve RL, Cooper DC, Nestler EJ, Han MH. Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons. Proceedings of the National Academy of Sciences of the United States of America. 107: 17011-6. PMID 20837544 DOI: 10.1073/pnas.1010077107  1
2010 Feng J, Nestler EJ. MeCP2 and drug addiction. Nature Neuroscience. 13: 1039-41. PMID 20740030 DOI: 10.1038/nn0910-1039  1
2010 LaPlant Q, Vialou V, Covington HE, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, ... ... Nestler EJ, et al. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nature Neuroscience. 13: 1137-43. PMID 20729844 DOI: 10.1038/nn.2619  1
2010 Bateup HS, Santini E, Shen W, Birnbaum S, Valjent E, Surmeier DJ, Fisone G, Nestler EJ, Greengard P. Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors. Proceedings of the National Academy of Sciences of the United States of America. 107: 14845-50. PMID 20682746 DOI: 10.1073/pnas.1009874107  1
2010 Bale TL, Baram TZ, Brown AS, Goldstein JM, Insel TR, McCarthy MM, Nemeroff CB, Reyes TM, Simerly RB, Susser ES, Nestler EJ. Early life programming and neurodevelopmental disorders. Biological Psychiatry. 68: 314-9. PMID 20674602 DOI: 10.1016/j.biopsych.2010.05.028  1
2010 Larson EB, Akkentli F, Edwards S, Graham DL, Simmons DL, Alibhai IN, Nestler EJ, Self DW. Striatal regulation of ΔFosB, FosB, and cFos during cocaine self-administration and withdrawal. Journal of Neurochemistry. 115: 112-22. PMID 20633205 DOI: 10.1111/j.1471-4159.2010.06907.x  1
2010 Pitchers KK, Frohmader KS, Vialou V, Mouzon E, Nestler EJ, Lehman MN, Coolen LM. ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward. Genes, Brain, and Behavior. 9: 831-40. PMID 20618447 DOI: 10.1111/j.1601-183X.2010.00621.x  1
2010 Iñiguez SD, Warren BL, Neve RL, Russo SJ, Nestler EJ, Bolaños-Guzmán CA. Viral-mediated expression of extracellular signal-regulated kinase-2 in the ventral tegmental area modulates behavioral responses to cocaine. Behavioural Brain Research. 214: 460-4. PMID 20561901 DOI: 10.1016/j.bbr.2010.05.040  1
2010 Iñiguez SD, Vialou V, Warren BL, Cao JL, Alcantara LF, Davis LC, Manojlovic Z, Neve RL, Russo SJ, Han MH, Nestler EJ, Bolaños-Guzmán CA. Extracellular signal-regulated kinase-2 within the ventral tegmental area regulates responses to stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7652-63. PMID 20519540 DOI: 10.1523/JNEUROSCI.0951-10.2010  1
2010 Vialou V, Robison AJ, Laplant QC, Covington HE, Dietz DM, Ohnishi YN, Mouzon E, Rush AJ, Watts EL, Wallace DL, Iñiguez SD, Ohnishi YH, Steiner MA, Warren BL, Krishnan V, ... ... Nestler EJ, et al. DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses. Nature Neuroscience. 13: 745-52. PMID 20473292 DOI: 10.1038/nn.2551  1
2010 Enwright JF, Wald M, Paddock M, Hoffman E, Arey R, Edwards S, Spencer S, Nestler EJ, McClung CA. DeltaFosB indirectly regulates Cck promoter activity. Brain Research. 1329: 10-20. PMID 20226774 DOI: 10.1016/j.brainres.2010.02.081  1
2010 Russo SJ, Dietz DM, Dumitriu D, Morrison JH, Malenka RC, Nestler EJ. The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens. Trends in Neurosciences. 33: 267-76. PMID 20207024 DOI: 10.1016/j.tins.2010.02.002  1
2010 Lagace DC, Donovan MH, DeCarolis NA, Farnbauch LA, Malhotra S, Berton O, Nestler EJ, Krishnan V, Eisch AJ. Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance. Proceedings of the National Academy of Sciences of the United States of America. 107: 4436-41. PMID 20176946 DOI: 10.1073/pnas.0910072107  1
2010 Sun H, Green TA, Theobald DE, Birnbaum SG, Graham DL, Zeeb FD, Nestler EJ, Winstanley CA. Yohimbine increases impulsivity through activation of cAMP response element binding in the orbitofrontal cortex. Biological Psychiatry. 67: 649-56. PMID 20163788 DOI: 10.1016/j.biopsych.2009.11.030  1
2010 Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS. Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proceedings of the National Academy of Sciences of the United States of America. 107: 2669-74. PMID 20133768 DOI: 10.1073/pnas.0910658107  1
2010 Liu Y, Aragona BJ, Young KA, Dietz DM, Kabbaj M, Mazei-Robison M, Nestler EJ, Wang Z. Nucleus accumbens dopamine mediates amphetamine-induced impairment of social bonding in a monogamous rodent species. Proceedings of the National Academy of Sciences of the United States of America. 107: 1217-22. PMID 20080553 DOI: 10.1073/pnas.0911998107  1
2010 Chuang JC, Krishnan V, Yu HG, Mason B, Cui H, Cui H, Wilkinson MB, Zigman JM, Elmquist JK, Nestler EJ, Lutter M. A beta3-adrenergic-leptin-melanocortin circuit regulates behavioral and metabolic changes induced by chronic stress. Biological Psychiatry. 67: 1075-82. PMID 20060958 DOI: 10.1016/j.biopsych.2009.12.003  1
2010 Maze I, Covington HE, Dietz DM, LaPlant Q, Renthal W, Russo SJ, Mechanic M, Mouzon E, Neve RL, Haggarty SJ, Ren Y, Sampath SC, Hurd YL, Greengard P, Tarakhovsky A, ... ... Nestler EJ, et al. Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science (New York, N.Y.). 327: 213-6. PMID 20056891 DOI: 10.1126/science.1179438  1
2010 Covington HE, Vialou V, Nestler EJ. From synapse to nucleus: novel targets for treating depression. Neuropharmacology. 58: 683-93. PMID 20018197 DOI: 10.1016/j.neuropharm.2009.12.004  1
2010 Han MH, Renthal W, Ring RH, Rahman Z, Psifogeorgou K, Howland D, Birnbaum S, Young K, Neve R, Nestler EJ, Zachariou V. Brain region specific actions of regulator of G protein signaling 4 oppose morphine reward and dependence but promote analgesia. Biological Psychiatry. 67: 761-9. PMID 19914603 DOI: 10.1016/j.biopsych.2009.08.041  1
2010 Green TA, Alibhai IN, Roybal CN, Winstanley CA, Theobald DE, Birnbaum SG, Graham AR, Unterberg S, Graham DL, Vialou V, Bass CE, Terwilliger EF, Bardo MT, Nestler EJ. Environmental enrichment produces a behavioral phenotype mediated by low cyclic adenosine monophosphate response element binding (CREB) activity in the nucleus accumbens. Biological Psychiatry. 67: 28-35. PMID 19709647 DOI: 10.1016/j.biopsych.2009.06.022  1
2010 Tecott LH, Nestler EJ. Rodent Behavior: Approaches Encyclopedia of Neuroscience. 407-413. DOI: 10.1016/B978-008045046-9.00887-1  1
2010 Kumar A, Green TA, Russo SJ, Renthal W, Nestler EJ. Transcription and Reward Systems Encyclopedia of Neuroscience. 1063-1070. DOI: 10.1016/B978-008045046-9.00195-9  1
2009 Renthal W, Nestler EJ. Chromatin regulation in drug addiction and depression. Dialogues in Clinical Neuroscience. 11: 257-68. PMID 19877494  1
2009 Covington HE, Maze I, LaPlant QC, Vialou VF, Ohnishi YN, Berton O, Fass DM, Renthal W, Rush AJ, Wu EY, Ghose S, Krishnan V, Russo SJ, Tamminga C, Haggarty SJ, ... Nestler EJ, et al. Antidepressant actions of histone deacetylase inhibitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11451-60. PMID 19759294 DOI: 10.1523/JNEUROSCI.1758-09.2009  1
2009 Hedges VL, Chakravarty S, Nestler EJ, Meisel RL. Delta FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters. Genes, Brain, and Behavior. 8: 442-9. PMID 19566711 DOI: 10.1111/j.1601-183X.2009.00491.x  1
2009 Renthal W, Nestler EJ. Histone acetylation in drug addiction. Seminars in Cell & Developmental Biology. 20: 387-94. PMID 19560043 DOI: 10.1016/j.semcdb.2009.01.005  1
2009 Wilkinson MB, Xiao G, Kumar A, LaPlant Q, Renthal W, Sikder D, Kodadek TJ, Nestler EJ. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7820-32. PMID 19535594 DOI: 10.1523/JNEUROSCI.0932-09.2009  1
2009 Watanabe H, Henriksson R, Ohnishi YN, Ohnishi YH, Harper C, Sheedy D, Garrick T, Nyberg F, Nestler EJ, Bakalkin G, Yakovleva T. FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics. Addiction Biology. 14: 294-7. PMID 19523044 DOI: 10.1111/j.1369-1600.2009.00155.x  1
2009 Berton O, Guigoni C, Li Q, Bioulac BH, Aubert I, Gross CE, Dileone RJ, Nestler EJ, Bezard E. Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease. Biological Psychiatry. 66: 554-61. PMID 19481198 DOI: 10.1016/j.biopsych.2009.04.005  1
2009 Feder A, Nestler EJ, Charney DS. Psychobiology and molecular genetics of resilience. Nature Reviews. Neuroscience. 10: 446-57. PMID 19455174 DOI: 10.1038/nrn2649  1
2009 Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, ... ... Nestler EJ, et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron. 62: 335-48. PMID 19447090 DOI: 10.1016/j.neuron.2009.03.026  1
2009 Dietz DM, Dietz KC, Nestler EJ, Russo SJ. Molecular mechanisms of psychostimulant-induced structural plasticity. Pharmacopsychiatry. 42: S69-78. PMID 19434558 DOI: 10.1055/s-0029-1202847  1
2009 Nestler EJ. Effects of drugs of abuse on the brain during development. Foreword. Developmental Neuroscience. 31: 6. PMID 19372682 DOI: 10.1159/000209398  1
2009 Freet CS, Steffen C, Nestler EJ, Grigson PS. Overexpression of DeltaFosB is associated with attenuated cocaine-induced suppression of saccharin intake in mice. Behavioral Neuroscience. 123: 397-407. PMID 19331462 DOI: 10.1037/a0015033  1
2009 Russo SJ, Wilkinson MB, Mazei-Robison MS, Dietz DM, Maze I, Krishnan V, Renthal W, Graham A, Birnbaum SG, Green TA, Robison B, Lesselyong A, Perrotti LI, Bolaños CA, Kumar A, ... ... Nestler EJ, et al. Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3529-37. PMID 19295158 DOI: 10.1523/JNEUROSCI.6173-08.2009  1
2009 LaPlant Q, Chakravarty S, Vialou V, Mukherjee S, Koo JW, Kalahasti G, Bradbury KR, Taylor SV, Maze I, Kumar A, Graham A, Birnbaum SG, Krishnan V, Truong HT, Neve RL, ... Nestler EJ, et al. Role of nuclear factor kappaB in ovarian hormone-mediated stress hypersensitivity in female mice. Biological Psychiatry. 65: 874-80. PMID 19251249 DOI: 10.1016/j.biopsych.2009.01.024  1
2009 Dinieri JA, Nemeth CL, Parsegian A, Carle T, Gurevich VV, Gurevich E, Neve RL, Nestler EJ, Carlezon WA. Altered sensitivity to rewarding and aversive drugs in mice with inducible disruption of cAMP response element-binding protein function within the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1855-9. PMID 19211892 DOI: 10.1523/JNEUROSCI.5104-08.2009  1
2009 Lutter M, Nestler EJ. Homeostatic and hedonic signals interact in the regulation of food intake. The Journal of Nutrition. 139: 629-32. PMID 19176746 DOI: 10.3945/jn.108.097618  0.32
2009 Wallace DL, Han MH, Graham DL, Green TA, Vialou V, Iñiguez SD, Cao JL, Kirk A, Chakravarty S, Kumar A, Krishnan V, Neve RL, Cooper DC, Bolaños CA, Barrot M, ... ... Nestler EJ, et al. CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits. Nature Neuroscience. 12: 200-9. PMID 19151710 DOI: 10.1038/nn.2257  1
2009 Winstanley CA, Green TA, Theobald DE, Renthal W, LaPlant Q, DiLeone RJ, Chakravarty S, Nestler EJ. DeltaFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine. Pharmacology, Biochemistry, and Behavior. 93: 278-84. PMID 19135469 DOI: 10.1016/j.pbb.2008.12.007  1
2009 Ulery-Reynolds PG, Castillo MA, Vialou V, Russo SJ, Nestler EJ. Phosphorylation of DeltaFosB mediates its stability in vivo. Neuroscience. 158: 369-72. PMID 19041372 DOI: 10.1016/j.neuroscience.2008.10.059  1
2009 Graham DL, Krishnan V, Larson EB, Graham A, Edwards S, Bachtell RK, Simmons D, Gent LM, Berton O, Bolanos CA, DiLeone RJ, Parada LF, Nestler EJ, Self DW. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biological Psychiatry. 65: 696-701. PMID 18990365 DOI: 10.1016/j.biopsych.2008.09.032  1
2009 Russo SJ, Mazei-Robison MS, Ables JL, Nestler EJ. Neurotrophic factors and structural plasticity in addiction. Neuropharmacology. 56: 73-82. PMID 18647613 DOI: 10.1016/j.neuropharm.2008.06.059  1
2009 Winstanley CA, Bachtell RK, Theobald DE, Laali S, Green TA, Kumar A, Chakravarty S, Self DW, Nestler EJ. Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. Cerebral Cortex (New York, N.Y. : 1991). 19: 435-44. PMID 18539927 DOI: 10.1093/cercor/bhn094  1
2008 Borrelli E, Nestler EJ, Allis CD, Sassone-Corsi P. Decoding the epigenetic language of neuronal plasticity. Neuron. 60: 961-74. PMID 19109904 DOI: 10.1016/j.neuron.2008.10.012  1
2008 Jiang Y, Langley B, Lubin FD, Renthal W, Wood MA, Yasui DH, Kumar A, Nestler EJ, Akbarian S, Beckel-Mitchener AC. Epigenetics in the nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11753-9. PMID 19005036 DOI: 10.1523/JNEUROSCI.3797-08.2008  1
2008 Krishnan V, Nestler EJ. The molecular neurobiology of depression. Nature. 455: 894-902. PMID 18923511 DOI: 10.1038/nature07455  0.68
2008 Wallace DL, Vialou V, Rios L, Carle-Florence TL, Chakravarty S, Kumar A, Graham DL, Green TA, Kirk A, Iñiguez SD, Perrotti LI, Barrot M, DiLeone RJ, Nestler EJ, Bolaños-Guzmán CA. The influence of DeltaFosB in the nucleus accumbens on natural reward-related behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10272-7. PMID 18842886 DOI: 10.1523/JNEUROSCI.1531-08.2008  1
2008 Iñiguez SD, Warren BL, Neve RL, Nestler EJ, Russo SJ, Bolaños-Guzmán CA. Insulin receptor substrate-2 in the ventral tegmental area regulates behavioral responses to cocaine. Behavioral Neuroscience. 122: 1172-7. PMID 18823173 DOI: 10.1037/a0012893  1
2008 Pulipparacharuvil S, Renthal W, Hale CF, Taniguchi M, Xiao G, Kumar A, Russo SJ, Sikder D, Dewey CM, Davis MM, Greengard P, Nairn AC, Nestler EJ, Cowan CW. Cocaine regulates MEF2 to control synaptic and behavioral plasticity. Neuron. 59: 621-33. PMID 18760698 DOI: 10.1016/j.neuron.2008.06.020  1
2008 Kim KS, Lee KW, Baek IS, Lim CM, Krishnan V, Lee JK, Nestler EJ, Han PL. Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. Journal of Neurochemistry. 107: 105-15. PMID 18673448 DOI: 10.1111/j.1471-4159.2008.05592.x  1
2008 Teegarden SL, Nestler EJ, Bale TL. Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet. Biological Psychiatry. 64: 941-50. PMID 18657800 DOI: 10.1016/j.biopsych.2008.06.007  1
2008 Krishnan V, Han MH, Mazei-Robison M, Iñiguez SD, Ables JL, Vialou V, Berton O, Ghose S, Covington HE, Wiley MD, Henderson RP, Neve RL, Eisch AJ, Tamminga CA, Russo SJ, ... ... Nestler EJ, et al. AKT signaling within the ventral tegmental area regulates cellular and behavioral responses to stressful stimuli. Biological Psychiatry. 64: 691-700. PMID 18639865 DOI: 10.1016/j.biopsych.2008.06.003  1
2008 Renthal W, Nestler EJ. Epigenetic mechanisms in drug addiction. Trends in Molecular Medicine. 14: 341-50. PMID 18635399 DOI: 10.1016/j.molmed.2008.06.004  1
2008 Renthal W, Carle TL, Maze I, Covington HE, Truong HT, Alibhai I, Kumar A, Montgomery RL, Olson EN, Nestler EJ. Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7344-9. PMID 18632938 DOI: 10.1523/JNEUROSCI.1043-08.2008  1
2008 Lutter M, Sakata I, Osborne-Lawrence S, Rovinsky SA, Anderson JG, Jung S, Birnbaum S, Yanagisawa M, Elmquist JK, Nestler EJ, Zigman JM. The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress. Nature Neuroscience. 11: 752-3. PMID 18552842 DOI: 10.1038/nn.2139  1
2008 Krishnan V, Graham A, Mazei-Robison MS, Lagace DC, Kim KS, Birnbaum S, Eisch AJ, Han PL, Storm DR, Zachariou V, Nestler EJ. Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting. Biological Psychiatry. 64: 336-43. PMID 18468583 DOI: 10.1016/j.biopsych.2008.03.026  1
2008 Charlton JJ, Allen PB, Psifogeorgou K, Chakravarty S, Gomes I, Neve RL, Devi LA, Greengard P, Nestler EJ, Zachariou V. Multiple actions of spinophilin regulate mu opioid receptor function. Neuron. 58: 238-47. PMID 18439408 DOI: 10.1016/j.neuron.2008.02.006  1
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/j.biopsych.2008.03.005  1
2008 Lutter M, Krishnan V, Russo SJ, Jung S, McClung CA, Nestler EJ. Orexin signaling mediates the antidepressant-like effect of calorie restriction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3071-5. PMID 18354010 DOI: 10.1523/JNEUROSCI.5584-07.2008  1
2008 Green TA, Alibhai IN, Unterberg S, Neve RL, Ghose S, Tamminga CA, Nestler EJ. Induction of activating transcription factors (ATFs) ATF2, ATF3, and ATF4 in the nucleus accumbens and their regulation of emotional behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2025-32. PMID 18305237 DOI: 10.1523/JNEUROSCI.5273-07.2008  1
2008 Perrotti LI, Weaver RR, Robison B, Renthal W, Maze I, Yazdani S, Elmore RG, Knapp DJ, Selley DE, Martin BR, Sim-Selley L, Bachtell RK, Self DW, Nestler EJ. Distinct patterns of DeltaFosB induction in brain by drugs of abuse. Synapse (New York, N.Y.). 62: 358-69. PMID 18293355 DOI: 10.1002/syn.20500  1
2008 Zachariou V, Liu R, LaPlant Q, Xiao G, Renthal W, Chan GC, Storm DR, Aghajanian G, Nestler EJ. Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies. Biological Psychiatry. 63: 1013-21. PMID 18222416 DOI: 10.1016/j.biopsych.2007.11.021  1
2008 Potenza MN, Brodkin ES, Yang BZ, Birnbaum SG, Nestler EJ, Gelernter J. Quantitative trait locus analysis identifies rat genomic regions related to amphetamine-induced locomotion and Galpha(i3) levels in nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2735-46. PMID 18216777 DOI: 10.1038/sj.npp.1301667  1
2008 Huang YH, Lin Y, Brown TE, Han MH, Saal DB, Neve RL, Zukin RS, Sorg BA, Nestler EJ, Malenka RC, Dong Y. CREB modulates the functional output of nucleus accumbens neurons: a critical role of N-methyl-D-aspartate glutamate receptor (NMDAR) receptors. The Journal of Biological Chemistry. 283: 2751-60. PMID 18055458 DOI: 10.1074/jbc.M706578200  1
2008 Steiner MA, Marsicano G, Nestler EJ, Holsboer F, Lutz B, Wotjak CT. Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice. Psychoneuroendocrinology. 33: 54-67. PMID 17976922 DOI: 10.1016/j.psyneuen.2007.09.008  1
2008 McClung CA, Nestler EJ. Neuroplasticity mediated by altered gene expression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3-17. PMID 17728700 DOI: 10.1038/sj.npp.1301544  1
2007 Renthal W, Maze I, Krishnan V, Covington HE, Xiao G, Kumar A, Russo SJ, Graham A, Tsankova N, Kippin TE, Kerstetter KA, Neve RL, Haggarty SJ, McKinsey TA, Bassel-Duby R, ... ... Nestler EJ, et al. Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron. 56: 517-29. PMID 17988634 DOI: 10.1016/j.neuron.2007.09.032  1
2007 Krishnan V, Han MH, Graham DL, Berton O, Renthal W, Russo SJ, Laplant Q, Graham A, Lutter M, Lagace DC, Ghose S, Reister R, Tannous P, Green TA, Neve RL, ... ... Nestler EJ, et al. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell. 131: 391-404. PMID 17956738 DOI: 10.1016/j.cell.2007.09.018  1
2007 Winstanley CA, LaPlant Q, Theobald DE, Green TA, Bachtell RK, Perrotti LI, DiLeone RJ, Russo SJ, Garth WJ, Self DW, Nestler EJ. DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10497-507. PMID 17898221 DOI: 10.1523/JNEUROSCI.2566-07.2007  1
2007 Berton O, Covington HE, Ebner K, Tsankova NM, Carle TL, Ulery P, Bhonsle A, Barrot M, Krishnan V, Singewald GM, Singewald N, Birnbaum S, Neve RL, Nestler EJ. Induction of deltaFosB in the periaqueductal gray by stress promotes active coping responses. Neuron. 55: 289-300. PMID 17640529 DOI: 10.1016/j.neuron.2007.06.033  1
2007 Jorissen HJ, Ulery PG, Henry L, Gourneni S, Nestler EJ, Rudenko G. Dimerization and DNA-binding properties of the transcription factor DeltaFosB. Biochemistry. 46: 8360-72. PMID 17580968 DOI: 10.1021/bi700494v  0.72
2007 Carle TL, Ohnishi YN, Ohnishi YH, Alibhai IN, Wilkinson MB, Kumar A, Nestler EJ. Proteasome-dependent and -independent mechanisms for FosB destabilization: identification of FosB degron domains and implications for DeltaFosB stability. The European Journal of Neuroscience. 25: 3009-19. PMID 17561814 DOI: 10.1111/j.1460-9568.2007.05575.x  1
2007 Wolf DH, Nestler EJ, Russell DS. Regulation of neuronal PLCgamma by chronic morphine. Brain Research. 1156: 9-20. PMID 17524370 DOI: 10.1016/j.brainres.2007.04.059  1
2007 Tsankova N, Renthal W, Kumar A, Nestler EJ. Epigenetic regulation in psychiatric disorders. Nature Reviews. Neuroscience. 8: 355-67. PMID 17453016 DOI: 10.1038/nrn2132  1
2007 Roybal K, Theobold D, Graham A, DiNieri JA, Russo SJ, Krishnan V, Chakravarty S, Peevey J, Oehrlein N, Birnbaum S, Vitaterna MH, Orsulak P, Takahashi JS, Nestler EJ, Carlezon WA, et al. Mania-like behavior induced by disruption of CLOCK. Proceedings of the National Academy of Sciences of the United States of America. 104: 6406-11. PMID 17379666 DOI: 10.1073/pnas.0609625104  1
2007 Taylor JR, Lynch WJ, Sanchez H, Olausson P, Nestler EJ, Bibb JA. Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proceedings of the National Academy of Sciences of the United States of America. 104: 4147-52. PMID 17360491 DOI: 10.1073/pnas.0610288104  1
2007 Alibhai IN, Green TA, Potashkin JA, Nestler EJ. Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies. Brain Research. 1143: 22-33. PMID 17324382 DOI: 10.1016/j.brainres.2007.01.069  1
2007 Ulery PG, Nestler EJ. Regulation of DeltaFosB transcriptional activity by Ser27 phosphorylation. The European Journal of Neuroscience. 25: 224-30. PMID 17241283 DOI: 10.1111/j.1460-9568.2006.05262.x  0.72
2007 Russo SJ, Bolanos CA, Theobald DE, DeCarolis NA, Renthal W, Kumar A, Winstanley CA, Renthal NE, Wiley MD, Self DW, Russell DS, Neve RL, Eisch AJ, Nestler EJ. IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nature Neuroscience. 10: 93-9. PMID 17143271 DOI: 10.1038/nn1812  1
2007 Olson VG, Green TA, Neve RL, Nestler EJ. Regulation of morphine reward and feeding by CREB in the lateral hypothalamus. Synapse (New York, N.Y.). 61: 110-3. PMID 17117424 DOI: 10.1002/syn.20344  1
2007 Olson VG, Nestler EJ. Topographical organization of GABAergic neurons within the ventral tegmental area of the rat. Synapse (New York, N.Y.). 61: 87-95. PMID 17117419 DOI: 10.1002/syn.20345  1
2007 Monteggia LM, Luikart B, Barrot M, Theobold D, Malkovska I, Nef S, Parada LF, Nestler EJ. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors. Biological Psychiatry. 61: 187-97. PMID 16697351 DOI: 10.1016/j.biopsych.2006.03.021  1
2006 Olausson P, Jentsch JD, Tronson N, Neve RL, Nestler EJ, Taylor JR. DeltaFosB in the nucleus accumbens regulates food-reinforced instrumental behavior and motivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9196-204. PMID 16957076 DOI: 10.1523/JNEUROSCI.1124-06.2006  1
2006 Green TA, Alibhai IN, Hommel JD, DiLeone RJ, Kumar A, Theobald DE, Neve RL, Nestler EJ. Induction of inducible cAMP early repressor expression in nucleus accumbens by stress or amphetamine increases behavioral responses to emotional stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8235-42. PMID 16899718 DOI: 10.1523/JNEUROSCI.0880-06.2006  1
2006 Hyman SE, Malenka RC, Nestler EJ. Neural mechanisms of addiction: the role of reward-related learning and memory. Annual Review of Neuroscience. 29: 565-98. PMID 16776597 DOI: 10.1146/annurev.neuro.29.051605.113009  1
2006 Ulery PG, Rudenko G, Nestler EJ. Regulation of DeltaFosB stability by phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5131-42. PMID 16687504 DOI: 10.1523/JNEUROSCI.4970-05.2006  0.72
2006 Han MH, Bolaños CA, Green TA, Olson VG, Neve RL, Liu RJ, Aghajanian GK, Nestler EJ. Role of cAMP response element-binding protein in the rat locus ceruleus: regulation of neuronal activity and opiate withdrawal behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4624-9. PMID 16641242 DOI: 10.1523/JNEUROSCI.4701-05.2006  1
2006 Allen PB, Zachariou V, Svenningsson P, Lepore AC, Centonze D, Costa C, Rossi S, Bender G, Chen G, Feng J, Snyder GL, Bernardi G, Nestler EJ, Yan Z, Calabresi P, et al. Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity. Neuroscience. 140: 897-911. PMID 16600521 DOI: 10.1016/j.neuroscience.2006.02.067  1
2006 Nestler EJ, Carlezon WA. The mesolimbic dopamine reward circuit in depression. Biological Psychiatry. 59: 1151-9. PMID 16566899 DOI: 10.1016/j.biopsych.2005.09.018  1
2006 Kim KS, Lee KW, Lee KW, Im JY, Yoo JY, Kim SW, Lee JK, Nestler EJ, Han PL. Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action. Proceedings of the National Academy of Sciences of the United States of America. 103: 3908-13. PMID 16537460 DOI: 10.1073/pnas.0508812103  1
2006 Dong Y, Green T, Saal D, Marie H, Neve R, Nestler EJ, Malenka RC. CREB modulates excitability of nucleus accumbens neurons. Nature Neuroscience. 9: 475-7. PMID 16520736 DOI: 10.1038/nn1661  1
2006 Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nature Neuroscience. 9: 519-25. PMID 16501568 DOI: 10.1038/nn1659  1
2006 Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science (New York, N.Y.). 311: 864-8. PMID 16469931 DOI: 10.1126/science.1120972  1
2006 Tamminga CA, Nestler EJ. Pathological gambling: focusing on the addiction, not the activity. The American Journal of Psychiatry. 163: 180-1. PMID 16449466 DOI: 10.1176/appi.ajp.163.2.180  0.72
2006 Berton O, Nestler EJ. New approaches to antidepressant drug discovery: beyond monoamines. Nature Reviews. Neuroscience. 7: 137-51. PMID 16429123 DOI: 10.1038/nrn1846  1
2006 Zachariou V, Bolanos CA, Selley DE, Theobald D, Cassidy MP, Kelz MB, Shaw-Lutchman T, Berton O, Sim-Selley LJ, Dileone RJ, Kumar A, Nestler EJ. An essential role for DeltaFosB in the nucleus accumbens in morphine action. Nature Neuroscience. 9: 205-11. PMID 16415864 DOI: 10.1038/nn1636  1
2006 Zachariou V, Sgambato-Faure V, Sasaki T, Svenningsson P, Berton O, Fienberg AA, Nairn AC, Greengard P, Nestler EJ. Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 555-62. PMID 16123776 DOI: 10.1038/sj.npp.1300832  1
2005 Colvis CM, Pollock JD, Goodman RH, Impey S, Dunn J, Mandel G, Champagne FA, Mayford M, Korzus E, Kumar A, Renthal W, Theobald DE, Nestler EJ. Epigenetic mechanisms and gene networks in the nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10379-89. PMID 16280577 DOI: 10.1523/JNEUROSCI.4119-05.2005  1
2005 Kumar A, Choi KH, Renthal W, Tsankova NM, Theobald DE, Truong HT, Russo SJ, Laplant Q, Sasaki TS, Whistler KN, Neve RL, Self DW, Nestler EJ. Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron. 48: 303-14. PMID 16242410 DOI: 10.1016/j.neuron.2005.09.023  1
2005 Neve RL, Neve KA, Nestler EJ, Carlezon WA. Use of herpes virus amplicon vectors to study brain disorders. Biotechniques. 39: 381-91. PMID 16206910 DOI: 10.2144/05393PS01  1
2005 Carlezon WA, Duman RS, Nestler EJ. The many faces of CREB. Trends in Neurosciences. 28: 436-45. PMID 15982754 DOI: 10.1016/j.tins.2005.06.005  1
2005 McClung CA, Nestler EJ, Zachariou V. Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6005-15. PMID 15976090 DOI: 10.1523/JNEUROSCI.0062-05.2005  1
2005 McClung CA, Sidiropoulou K, Vitaterna M, Takahashi JS, White FJ, Cooper DC, Nestler EJ. Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proceedings of the National Academy of Sciences of the United States of America. 102: 9377-81. PMID 15967985 DOI: 10.1073/pnas.0503584102  1
2005 Olson VG, Zabetian CP, Bolanos CA, Edwards S, Barrot M, Eisch AJ, Hughes T, Self DW, Neve RL, Nestler EJ. Regulation of drug reward by cAMP response element-binding protein: evidence for two functionally distinct subregions of the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5553-62. PMID 15944383 DOI: 10.1523/JNEUROSCI.0345-05.2005  1
2005 Perrotti LI, Bolaños CA, Choi KH, Russo SJ, Edwards S, Ulery PG, Wallace DL, Self DW, Nestler EJ, Barrot M. DeltaFosB accumulates in a GABAergic cell population in the posterior tail of the ventral tegmental area after psychostimulant treatment. The European Journal of Neuroscience. 21: 2817-24. PMID 15926929 DOI: 10.1111/j.1460-9568.2005.04110.x  1
2005 Barrot M, Wallace DL, Bolaños CA, Graham DL, Perrotti LI, Neve RL, Chambliss H, Yin JC, Nestler EJ. Regulation of anxiety and initiation of sexual behavior by CREB in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 102: 8357-62. PMID 15923261 DOI: 10.1073/pnas.0500587102  1
2005 Hsu R, Taylor JR, Newton SS, Alvaro JD, Haile C, Han G, Hruby VJ, Nestler EJ, Duman RS. Blockade of melanocortin transmission inhibits cocaine reward. The European Journal of Neuroscience. 21: 2233-42. PMID 15869520 DOI: 10.1111/j.1460-9568.2005.04038.x  1
2005 Lucas G, Compan V, Charnay Y, Neve RL, Nestler EJ, Bockaert J, Barrot M, Debonnel G. Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: viral transfections, subacute and chronic treatments with 5-HT4 agonists. Biological Psychiatry. 57: 918-25. PMID 15820713 DOI: 10.1016/j.biopsych.2004.12.023  1
2005 Georgescu D, Sears RM, Hommel JD, Barrot M, Bolaños CA, Marsh DJ, Bednarek MA, Bibb JA, Maratos-Flier E, Nestler EJ, DiLeone RJ. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2933-40. PMID 15772353 DOI: 10.1523/JNEUROSCI.1714-04.2005  1
2005 Bolaños CA, Neve RL, Nestler EJ. Phospholipase C gamma in distinct regions of the ventral tegmental area differentially regulates morphine-induced locomotor activity. Synapse (New York, N.Y.). 56: 166-9. PMID 15765533 DOI: 10.1002/syn.20136  1
2004 McClung CA, Ulery PG, Perrotti LI, Zachariou V, Berton O, Nestler EJ. DeltaFosB: a molecular switch for long-term adaptation in the brain. Brain Research. Molecular Brain Research. 132: 146-54. PMID 15582154 DOI: 10.1016/j.molbrainres.2004.05.014  1
2004 Perrotti LI, Hadeishi Y, Ulery PG, Barrot M, Monteggia L, Duman RS, Nestler EJ. Induction of deltaFosB in reward-related brain structures after chronic stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10594-602. PMID 15564575 DOI: 10.1523/JNEUROSCI.2542-04.2004  1
2004 Monteggia LM, Barrot M, Powell CM, Berton O, Galanis V, Gemelli T, Meuth S, Nagy A, Greene RW, Nestler EJ. Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. 101: 10827-32. PMID 15249684 DOI: 10.1073/pnas.0402141101  1
2004 Tsankova NM, Kumar A, Nestler EJ. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5603-10. PMID 15201333 DOI: 10.1523/JNEUROSCI.0589-04.2004  1
2004 Tecott LH, Nestler EJ. Neurobehavioral assessment in the information age. Nature Neuroscience. 7: 462-6. PMID 15114359 DOI: 10.1038/nn1225  1
2004 Powell CM, Schoch S, Monteggia L, Barrot M, Matos MF, Feldmann N, Südhof TC, Nestler EJ. The presynaptic active zone protein RIM1alpha is critical for normal learning and memory. Neuron. 42: 143-53. PMID 15066271  0.72
2004 Potenza MN, Brodkin ES, Joe B, Luo X, Remmers EF, Wilder RL, Nestler EJ, Gelernter J. Genomic regions controlling corticosterone levels in rats. Biological Psychiatry. 55: 634-41. PMID 15013833 DOI: 10.1016/j.biopsych.2003.11.005  0.68
2004 Bolaños CA, Nestler EJ. Neurotrophic mechanisms in drug addiction. Neuromolecular Medicine. 5: 69-83. PMID 15001814 DOI: 10.1385/NMM:5:1:069  1
2004 Nestler EJ, Malenka RC. The addicted brain. Scientific American. 290: 78-85. PMID 14981881  1
2004 Chao J, Nestler EJ. Molecular neurobiology of drug addiction. Annual Review of Medicine. 55: 113-32. PMID 14746512 DOI: 10.1146/annurev.med.55.091902.103730  1
2004 Chen J, Newton SS, Zeng L, Adams DH, Dow AL, Madsen TM, Nestler EJ, Duman RS. Downregulation of the CCAAT-enhancer binding protein beta in deltaFosB transgenic mice and by electroconvulsive seizures. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 23-31. PMID 14532910 DOI: 10.1038/sj.npp.1300289  1
2003 Bolaños CA, Barrot M, Berton O, Wallace-Black D, Nestler EJ. Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood. Biological Psychiatry. 54: 1317-29. PMID 14675795 DOI: 10.1016/S0006-3223(03)00570-5  1
2003 Eisch AJ, Bolaños CA, de Wit J, Simonak RD, Pudiak CM, Barrot M, Verhaagen J, Nestler EJ. Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression. Biological Psychiatry. 54: 994-1005. PMID 14625141 DOI: 10.1016/j.biopsych.2003.08.003  1
2003 Zachariou V, Georgescu D, Sanchez N, Rahman Z, DiLeone R, Berton O, Neve RL, Sim-Selley LJ, Selley DE, Gold SJ, Nestler EJ. Essential role for RGS9 in opiate action. Proceedings of the National Academy of Sciences of the United States of America. 100: 13656-61. PMID 14595021 DOI: 10.1073/pnas.2232594100  1
2003 McClung CA, Nestler EJ. Regulation of gene expression and cocaine reward by CREB and DeltaFosB. Nature Neuroscience. 6: 1208-15. PMID 14566342 DOI: 10.1038/nn1143  1
2003 Bolaños CA, Perrotti LI, Edwards S, Eisch AJ, Barrot M, Olson VG, Russell DS, Neve RL, Nestler EJ. Phospholipase Cgamma in distinct regions of the ventral tegmental area differentially modulates mood-related behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7569-76. PMID 12930795  1
2003 Rahman Z, Schwarz J, Gold SJ, Zachariou V, Wein MN, Choi KH, Kovoor A, Chen CK, DiLeone RJ, Schwarz SC, Selley DE, Sim-Selley LJ, Barrot M, Luedtke RR, Self D, ... ... Nestler EJ, et al. RGS9 modulates dopamine signaling in the basal ganglia. Neuron. 38: 941-52. PMID 12818179 DOI: 10.1016/S0896-6273(03)00321-0  1
2003 DiLeone RJ, Georgescu D, Nestler EJ. Lateral hypothalamic neuropeptides in reward and drug addiction. Life Sciences. 73: 759-68. PMID 12801597 DOI: 10.1016/S0024-3205(03)00408-9  1
2003 Haberstock-Debic H, Wein M, Barrot M, Colago EE, Rahman Z, Neve RL, Pickel VM, Nestler EJ, von Zastrow M, Svingos AL. Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4324-32. PMID 12764121  1
2003 Georgescu D, Zachariou V, Barrot M, Mieda M, Willie JT, Eisch AJ, Yanagisawa M, Nestler EJ, DiLeone RJ. Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3106-11. PMID 12716916  1
2003 Peakman MC, Colby C, Perrotti LI, Tekumalla P, Carle T, Ulery P, Chao J, Duman C, Steffen C, Monteggia L, Allen MR, Stock JL, Duman RS, McNeish JD, Barrot M, ... ... Nestler EJ, et al. Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine. Brain Research. 970: 73-86. PMID 12706249 DOI: 10.1016/S0006-8993(03)02230-3  1
2003 Colby CR, Whisler K, Steffen C, Nestler EJ, Self DW. Striatal cell type-specific overexpression of DeltaFosB enhances incentive for cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2488-93. PMID 12657709  1
2003 Gold SJ, Han MH, Herman AE, Ni YG, Pudiak CM, Aghajanian GK, Liu RJ, Potts BW, Mumby SM, Nestler EJ. Regulation of RGS proteins by chronic morphine in rat locus coeruleus. The European Journal of Neuroscience. 17: 971-80. PMID 12653973 DOI: 10.1046/j.1460-9568.2003.02529.x  1
2003 Shaw-Lutchman TZ, Impey S, Storm D, Nestler EJ. Regulation of CRE-mediated transcription in mouse brain by amphetamine. Synapse (New York, N.Y.). 48: 10-7. PMID 12557267 DOI: 10.1002/syn.10172  1
2003 Norrholm SD, Bibb JA, Nestler EJ, Ouimet CC, Taylor JR, Greengard P. Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5. Neuroscience. 116: 19-22. PMID 12535933 DOI: 10.1016/S0306-4522(02)00560-2  1
2002 Newton SS, Thome J, Wallace TL, Shirayama Y, Schlesinger L, Sakai N, Chen J, Neve R, Nestler EJ, Duman RS. Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10883-90. PMID 12486182  1
2002 Carlezon WA, Nestler EJ. Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse? Trends in Neurosciences. 25: 610-5. PMID 12446127 DOI: 10.1016/S0166-2236(02)02289-0  0.72
2002 Chao JR, Ni YG, Bolaños CA, Rahman Z, DiLeone RJ, Nestler EJ. Characterization of the mouse adenylyl cyclase type VIII gene promoter: regulation by cAMP and CREB. The European Journal of Neuroscience. 16: 1284-94. PMID 12405989 DOI: 10.1046/j.1460-9568.2002.02186.x  1
2002 Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK, Hen R, Koester S, Lederhendler I, Meaney M, Robbins T, Winsky L, Zalcman S. Preclinical models: status of basic research in depression. Biological Psychiatry. 52: 503-28. PMID 12361666 DOI: 10.1016/S0006-3223(02)01405-1  1
2002 Gold SJ, Heifets BD, Pudiak CM, Potts BW, Nestler EJ. Regulation of regulators of G protein signaling mRNA expression in rat brain by acute and chronic electroconvulsive seizures. Journal of Neurochemistry. 82: 828-38. PMID 12358788 DOI: 10.1046/j.1471-4159.2002.01002.x  1
2002 Werme M, Messer C, Olson L, Gilden L, Thorén P, Nestler EJ, Brené S. Delta FosB regulates wheel running. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8133-8. PMID 12223567  1
2002 Barrot M, Olivier JD, Perrotti LI, DiLeone RJ, Berton O, Eisch AJ, Impey S, Storm DR, Neve RL, Yin JC, Zachariou V, Nestler EJ. CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli. Proceedings of the National Academy of Sciences of the United States of America. 99: 11435-40. PMID 12165570 DOI: 10.1073/pnas.172091899  1
2002 Jentsch JD, Olausson P, Nestler EJ, Taylor JR. Stimulation of protein kinase a activity in the rat amygdala enhances reward-related learning. Biological Psychiatry. 52: 111-8. PMID 12114002 DOI: 10.1016/S0006-3223(02)01358-6  1
2002 Chen J, Kelz MB, Zeng G, Steffen C, Shockett PE, Terwilliger G, Schatz DG, Nestler EJ. Inducible, reversible hair loss in transgenic mice. Transgenic Research. 11: 241-7. PMID 12113456 DOI: 10.1023/A:1015619604318  1
2002 Sakai N, Thome J, Newton SS, Chen J, Kelz MB, Steffen C, Nestler EJ, Duman RS. Inducible and brain region-specific CREB transgenic mice. Molecular Pharmacology. 61: 1453-64. PMID 12021407 DOI: 10.1124/mol.61.6.1453  1
2002 Akbarian S, Rios M, Liu RJ, Gold SJ, Fong HF, Zeiler S, Coppola V, Tessarollo L, Jones KR, Nestler EJ, Aghajanian GK, Jaenisch R. Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4153-62. PMID 12019333  1
2002 Nakagawa S, Kim JE, Lee R, Malberg JE, Chen J, Steffen C, Zhang YJ, Nestler EJ, Duman RS. Regulation of neurogenesis in adult mouse hippocampus by cAMP and the cAMP response element-binding protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3673-82. PMID 11978843  1
2002 Shaw-Lutchman TZ, Barrot M, Wallace T, Gilden L, Zachariou V, Impey S, Duman RS, Storm D, Nestler EJ. Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3663-72. PMID 11978842  1
2002 Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM. Neurobiology of depression. Neuron. 34: 13-25. PMID 11931738 DOI: 10.1016/S0896-6273(02)00653-0  1
2002 Mower AF, Liao DS, Nestler EJ, Neve RL, Ramoa AS. cAMP/Ca2+ response element-binding protein function is essential for ocular dominance plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2237-45. PMID 11896163  1
2002 Sims NA, Sabatakos G, Chen JS, Kelz MB, Nestler EJ, Baron R. Regulating DeltaFosB expression in adult Tet-Off-DeltaFosB transgenic mice alters bone formation and bone mass. Bone. 30: 32-9. PMID 11792562 DOI: 10.1016/S8756-3282(01)00622-6  1
2001 Brãuer AU, Savaskan NE, Kole MH, Plaschke M, Monteggia LM, Nestler EJ, Simburger E, Deisz RA, Ninnemann O, Nitsch R. Molecular and functional analysis of hyperpolarization-activated pacemaker channels in the hippocampus after entorhinal cortex lesion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2689-701. PMID 11726545 DOI: 10.1096/fj.01-0235com  1
2001 Tekumalla PK, Calon F, Rahman Z, Birdi S, Rajput AH, Hornykiewicz O, Di Paolo T, Bédard PJ, Nestler EJ. Elevated levels of DeltaFosB and RGS9 in striatum in Parkinson's disease. Biological Psychiatry. 50: 813-6. PMID 11720701 DOI: 10.1016/S0006-3223(01)01234-3  1
2001 Ang E, Chen J, Zagouras P, Magna H, Holland J, Schaeffer E, Nestler EJ. Induction of nuclear factor-kappaB in nucleus accumbens by chronic cocaine administration. Journal of Neurochemistry. 79: 221-4. PMID 11595774 DOI: 10.1046/j.1471-4159.2001.00563.x  1
2001 Nestler EJ, Barrot M, Self DW. DeltaFosB: a sustained molecular switch for addiction. Proceedings of the National Academy of Sciences of the United States of America. 98: 11042-6. PMID 11572966 DOI: 10.1073/pnas.191352698  1
2001 Pliakas AM, Carlson RR, Neve RL, Konradi C, Nestler EJ, Carlezon WA. Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7397-403. PMID 11549750  1
2001 Akbarian S, Bates B, Liu RJ, Skirboll SL, Pejchal T, Coppola V, Sun LD, Fan G, Kucera J, Wilson MA, Tessarollo L, Kosofsky BE, Taylor JR, Bothwell M, Nestler EJ, et al. Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal. Molecular Psychiatry. 6: 593-604. PMID 11526474 DOI: 10.1038/sj.mp.4000897  1
2001 Haile CN, Hiroi N, Nestler EJ, Kosten TA. Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats. Synapse (New York, N.Y.). 41: 179-90. PMID 11391778 DOI: 10.1002/syn.1073  1
2001 Hwang CK, D'Souza UM, Eisch AJ, Yajima S, Lammers CH, Yang Y, Lee SH, Kim YM, Nestler EJ, Mouradian MM. Dopamine receptor regulating factor, DRRF: a zinc finger transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 98: 7558-63. PMID 11390978 DOI: 10.1073/pnas.121635798  1
2001 Bibb JA, Chen J, Taylor JR, Svenningsson P, Nishi A, Snyder GL, Yan Z, Sagawa ZK, Ouimet CC, Nairn AC, Nestler EJ, Greengard P. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature. 410: 376-80. PMID 11268215 DOI: 10.1038/35066591  1
2001 Josselyn SA, Shi C, Carlezon WA, Neve RL, Nestler EJ, Davis M. Long-term memory is facilitated by cAMP response element-binding protein overexpression in the amygdala. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2404-12. PMID 11264314  1
2001 Chen AC, Eisch AJ, Sakai N, Takahashi M, Nestler EJ, Duman RS. Regulation of GFRalpha-1 and GFRalpha-2 mRNAs in rat brain by electroconvulsive seizure. Synapse (New York, N.Y.). 39: 42-50. PMID 11071708 DOI: 10.1002/1098-2396(20010101)39:1<42::AID-SYN6>3.0.CO;2-#  1
2000 Carlezon WA, Nestler EJ, Neve RL. Herpes simplex virus-mediated gene transfer as a tool for neuropsychiatric research. Critical Reviews in Neurobiology. 14: 47-67. PMID 11253955  1
2000 Kelz MB, Nestler EJ. deltaFosB: a molecular switch underlying long-term neural plasticity. Current Opinion in Neurology. 13: 715-20. PMID 11148675 DOI: 10.1097/00019052-200012000-00017  1
2000 Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 9104-10. PMID 11124987  1
2000 Chen J, Zhang Y, Kelz MB, Steffen C, Ang ES, Zeng L, Nestler EJ. Induction of cyclin-dependent kinase 5 in the hippocampus by chronic electroconvulsive seizures: role of [Delta]FosB. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8965-71. PMID 11124971  1
2000 Kelz MB, Kuszak JR, Yang Y, Ma W, Steffen C, Al-Ghoul K, Zhang YJ, Chen J, Nestler EJ, Spector A. DeltaFosB-induced cataract. Investigative Ophthalmology & Visual Science. 41: 3523-38. PMID 11006248  1
2000 Monteggia LM, Eisch AJ, Tang MD, Kaczmarek LK, Nestler EJ. Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain. Brain Research. Molecular Brain Research. 81: 129-39. PMID 11000485 DOI: 10.1016/S0169-328X(00)00155-8  1
2000 Sabatakos G, Sims NA, Chen J, Aoki K, Kelz MB, Amling M, Bouali Y, Mukhopadhyay K, Ford K, Nestler EJ, Baron R. Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis. Nature Medicine. 6: 985-90. PMID 10973317 DOI: 10.1038/79683  1
2000 Carlezon WA, Kosten TA, Nestler EJ. Behavioral interactions caused by combined administration of morphine and MK-801 in rats. Psychopharmacology. 151: 261-72. PMID 10972473  1
2000 Nankova BB, Rivkin M, Kelz M, Nestler EJ, Sabban EL. Fos-related antigen 2: potential mediator of the transcriptional activation in rat adrenal medulla evoked by repeated immobilization stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5647-53. PMID 10908602  1
2000 Eisch AJ, Barrot M, Schad CA, Self DW, Nestler EJ. Opiates inhibit neurogenesis in the adult rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 97: 7579-84. PMID 10840056 DOI: 10.1073/pnas.120552597  1
2000 Messer CJ, Eisch AJ, Carlezon WA, Whisler K, Shen L, Wolf DH, Westphal H, Collins F, Russell DS, Nestler EJ. Role for GDNF in biochemical and behavioral adaptations to drugs of abuse. Neuron. 26: 247-57. PMID 10798408  1
2000 Brené S, Messer C, Okado H, Hartley M, Heinemann SF, Nestler EJ. Regulation of GluR2 promoter activity by neurotrophic factors via a neuron-restrictive silencer element. The European Journal of Neuroscience. 12: 1525-33. PMID 10792430 DOI: 10.1046/j.1460-9568.2000.00040.x  1
2000 Carlezon WA, Haile CN, Coppersmith R, Hayashi Y, Malinow R, Neve RL, Nestler EJ. Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC62. PMID 10684909  1
2000 Jolas T, Nestler EJ, Aghajanian GK. Chronic morphine increases GABA tone on serotonergic neurons of the dorsal raphe nucleus: association with an up-regulation of the cyclic AMP pathway. Neuroscience. 95: 433-43. PMID 10658623 DOI: 10.1016/S0306-4522(99)00436-4  1
1999 Eisch AJ, Lammers CH, Yajima S, Mouradian MM, Nestler EJ. In vivo regulation of glial cell line-derived neurotrophic factor-inducible transcription factor by kainic acid. Neuroscience. 94: 629-36. PMID 10579223 DOI: 10.1016/S0306-4522(99)00302-4  1
1999 Nestler EJ, Alreja M, Aghajanian GK. Molecular control of locus coeruleus neurotransmission. Biological Psychiatry. 46: 1131-9. PMID 10560020 DOI: 10.1016/S0006-3223(99)00158-4  1
1999 Messer CJ, Son JH, Joh TH, Beck KD, Nestler EJ. Regulation of tyrosine hyroxylase gene transcription in ventral midbrain by glial cell line-derived neurotrophic factor. Synapse (New York, N.Y.). 34: 241-3. PMID 10523761 DOI: 10.1002/(SICI)1098-2396(19991201)34:3<241::AID-SYN8>3.0.CO;2-E  1
1999 Wolf DH, Numan S, Nestler EJ, Russell DS. Regulation of phospholipase Cgamma in the mesolimbic dopamine system by chronic morphine administration. Journal of Neurochemistry. 73: 1520-8. PMID 10501197 DOI: 10.1046/j.1471-4159.1999.0731520.x  1
1999 Kelz MB, Chen J, Carlezon WA, Whisler K, Gilden L, Beckmann AM, Steffen C, Zhang YJ, Marotti L, Self DW, Tkatch T, Baranauskas G, Surmeier DJ, Neve RL, Duman RS, ... ... Nestler EJ, et al. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature. 401: 272-6. PMID 10499584 DOI: 10.1038/45790  1
1999 Atkins JB, Chlan-Fourney J, Nye HE, Hiroi N, Carlezon WA, Nestler EJ. Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs. Synapse (New York, N.Y.). 33: 118-28. PMID 10400890 DOI: 10.1002/(SICI)1098-2396(199908)33:2<118::AID-SYN2>3.0.CO;2-L  1
1999 Charney DS, Innis RB, Nestler EJ, Davis KL, Nemeroff CB, Weinberger DR. Increasing public trust and confidence in psychiatric research. Biological Psychiatry. 46: 1-2. PMID 10394467  0.72
1999 Brodkin ES, Kosten TA, Haile CN, Heninger GR, Carlezon WA, Jatlow P, Remmers EF, Wilder RL, Nestler EJ. Dark Agouti and Fischer 344 rats: differential behavioral responses to morphine and biochemical differences in the ventral tegmental area. Neuroscience. 88: 1307-15. PMID 10336139 DOI: 10.1016/S0306-4522(98)00291-7  1
1999 Horger BA, Iyasere CA, Berhow MT, Messer CJ, Nestler EJ, Taylor JR. Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4110-22. PMID 10234039  1
1999 Ni YG, Gold SJ, Iredale PA, Terwilliger RZ, Duman RS, Nestler EJ. Region-specific regulation of RGS4 (Regulator of G-protein-signaling protein type 4) in brain by stress and glucocorticoids: in vivo and in vitro studies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3674-80. PMID 10233999  1
1999 Hiroi N, Fienberg AA, Haile CN, Alburges M, Hanson GR, Greengard P, Nestler EJ. Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice. The European Journal of Neuroscience. 11: 1114-8. PMID 10103106  1
1999 Rahman Z, Gold SJ, Potenza MN, Cowan CW, Ni YG, He W, Wensel TG, Nestler EJ. Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2016-26. PMID 10066255  1
1999 Carlezon WA, Rasmussen K, Nestler EJ. AMPA antagonist LY293558 blocks the development, without blocking the expression, of behavioral sensitization to morphine. Synapse (New York, N.Y.). 31: 256-62. PMID 10051106 DOI: 10.1002/(SICI)1098-2396(19990315)31:4<256::AID-SYN3>3.0.CO;2-E  1
1998 Carlezon WA, Thome J, Olson VG, Lane-Ladd SB, Brodkin ES, Hiroi N, Duman RS, Neve RL, Nestler EJ. Regulation of cocaine reward by CREB. Science (New York, N.Y.). 282: 2272-5. PMID 9856954 DOI: 10.1126/science.282.5397.2272  1
1998 Boundy VA, Gold SJ, Messer CJ, Chen J, Son JH, Joh TH, Nestler EJ. Regulation of tyrosine hydroxylase promoter activity by chronic morphine in TH9.0-LacZ transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9989-95. PMID 9822754  1
1998 Brodkin ES, Carlezon WA, Haile CN, Kosten TA, Heninger GR, Nestler EJ. Genetic analysis of behavioral, neuroendocrine, and biochemical parameters in inbred rodents: initial studies in Lewis and Fischer 344 rats and in A/J and C57BL/6J mice. Brain Research. 805: 55-68. PMID 9733917 DOI: 10.1016/S0006-8993(98)00663-5  1
1998 Chen J, Kelz MB, Zeng G, Sakai N, Steffen C, Shockett PE, Picciotto MR, Duman RS, Nestler EJ. Transgenic animals with inducible, targeted gene expression in brain. Molecular Pharmacology. 54: 495-503. PMID 9730908  1
1998 Self DW, Nestler EJ. Relapse to drug-seeking: neural and molecular mechanisms. Drug and Alcohol Dependence. 51: 49-60. PMID 9716929 DOI: 10.1016/S0376-8716(98)00065-9  1
1998 Hiroi N, Marek GJ, Brown JR, Ye H, Saudou F, Vaidya VA, Duman RS, Greenberg ME, Nestler EJ. Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 6952-62. PMID 9712664  1
1998 Fienberg AA, Hiroi N, Mermelstein PG, Song W, Snyder GL, Nishi A, Cheramy A, O'Callaghan JP, Miller DB, Cole DG, Corbett R, Haile CN, Cooper DC, Onn SP, Grace AA, ... ... Nestler EJ, et al. DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science (New York, N.Y.). 281: 838-42. PMID 9694658 DOI: 10.1126/science.281.5378.838  1
1998 Rocha BA, Scearce-Levie K, Lucas JJ, Hiroi N, Castanon N, Crabbe JC, Nestler EJ, Hen R. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor. Nature. 393: 175-8. PMID 9603521 DOI: 10.1038/30259  1
1998 Self DW, Genova LM, Hope BT, Barnhart WJ, Spencer JJ, Nestler EJ. Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1848-59. PMID 9465009  1
1998 Hiroi N, Nestler EJ. Nuclear memory: gene transcription and behavior. Advances in Pharmacology (San Diego, Calif.). 42: 1037-41. PMID 9328075 DOI: 10.1016/S1054-3589(08)60924-2  1
1997 Punch LJ, Self DW, Nestler EJ, Taylor JR. Opposite modulation of opiate withdrawal behaviors on microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaqueductal gray. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8520-7. PMID 9334424  1
1997 Hiroi N, Brown JR, Haile CN, Ye H, Greenberg ME, Nestler EJ. FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. Proceedings of the National Academy of Sciences of the United States of America. 94: 10397-402. PMID 9294222 DOI: 10.1073/pnas.94.19.10397  1
1997 Carlezon WA, Boundy VA, Haile CN, Lane SB, Kalb RG, Neve RL, Nestler EJ. Sensitization to morphine induced by viral-mediated gene transfer. Science (New York, N.Y.). 277: 812-4. PMID 9242609 DOI: 10.1126/science.277.5327.812  1
1997 Duman RS, Heninger GR, Nestler EJ. A molecular and cellular theory of depression. Archives of General Psychiatry. 54: 597-606. PMID 9236543  1
1997 Chen J, Kelz MB, Hope BT, Nakabeppu Y, Nestler EJ. Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4933-41. PMID 9185531  1
1997 Malison RT, Price LH, Nestler EJ, Heninger GR, Duman RS. Efficacy of papaverine addition for treatment-refractory major depression. The American Journal of Psychiatry. 154: 579-80. PMID 9090353  1
1997 Duman RS, Nestler EJ. Molecular biology, III. Tracking DNA: the Southern blot. The American Journal of Psychiatry. 154: 3. PMID 8988951  1
1997 Charlton ME, Sweetnam PM, Fitzgerald LW, Terwilliger RZ, Nestler EJ, Duman RS. Chronic ethanol administration regulates the expression of GABAA receptor alpha 1 and alpha 5 subunits in the ventral tegmental area and hippocampus. Journal of Neurochemistry. 68: 121-7. PMID 8978717  1
1996 Berhow MT, Hiroi N, Kobierski LA, Hyman SE, Nestler EJ. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 8019-26. PMID 8987828  1
1996 Iredale PA, Terwilliger R, Widnell KL, Nestler EJ, Duman RS. Differential regulation of corticotropin-releasing factor1 receptor expression by stress and agonist treatments in brain and cultured cells. Molecular Pharmacology. 50: 1103-10. PMID 8913341  1
1996 Alvaro JD, Tatro JB, Quillan JM, Fogliano M, Eisenhard M, Lerner MR, Nestler EJ, Duman RS. Morphine down-regulates melanocortin-4 receptor expression in brain regions that mediate opiate addiction. Molecular Pharmacology. 50: 583-91. PMID 8794897  1
1996 Berhow MT, Hiroi N, Nestler EJ. Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4707-15. PMID 8764658  1
1996 Doucet JP, Nakabeppu Y, Bedard PJ, Hope BT, Nestler EJ, Jasmin BJ, Chen JS, Iadarola MJ, St-Jean M, Wigle N, Blanchet P, Grondin R, Robertson GS. Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of deltaFosB-like protein(s) in both the rodent and primate striatum. The European Journal of Neuroscience. 8: 365-81. PMID 8714707  0.92
1996 Widnell KL, Chen JS, Iredale PA, Walker WH, Duman RS, Habener JF, Nestler EJ. Transcriptional regulation of CREB (cyclic AMP response element-binding protein) expression in CATH.a cells. Journal of Neurochemistry. 66: 1770-3. PMID 8627337  1
1996 Nibuya M, Nestler EJ, Duman RS. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2365-72. PMID 8601816  1
1996 Self DW, Barnhart WJ, Lehman DA, Nestler EJ. Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists. Science (New York, N.Y.). 271: 1586-9. PMID 8599115  1
1996 Widnell KL, Self DW, Lane SB, Russell DS, Vaidya VA, Miserendino MJ, Rubin CS, Duman RS, Nestler EJ. Regulation of CREB expression: in vivo evidence for a functional role in morphine action in the nucleus accumbens. The Journal of Pharmacology and Experimental Therapeutics. 276: 306-15. PMID 8558448  1
1995 Self DW, McClenahan AW, Beitner-Johnson D, Terwilliger RZ, Nestler EJ. Biochemical adaptations in the mesolimbic dopamine system in response to heroin self-administration. Synapse (New York, N.Y.). 21: 312-8. PMID 8869161 DOI: 10.1002/syn.890210405  1
1995 Ortiz J, Fitzgerald LW, Charlton M, Lane S, Trevisan L, Guitart X, Shoemaker W, Duman RS, Nestler EJ. Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system. Synapse (New York, N.Y.). 21: 289-98. PMID 8869159 DOI: 10.1002/syn.890210403  1
1995 Lee MJ, Saijoh K, Nestler EJ, Duman RS, Sumino K. Regional differences in expression of osteonectin mRNA after administration of cadmium to rats. Archives of Toxicology. 69: 590-5. PMID 8660135 DOI: 10.1007/s002040050218  1
1995 Berhow MT, Russell DS, Terwilliger RZ, Beitner-Johnson D, Self DW, Lindsay RM, Nestler EJ. Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system. Neuroscience. 68: 969-79. PMID 8545003 DOI: 10.1016/0306-4522(95)00207-Y  1
1995 Nye HE, Hope BT, Kelz MB, Iadarola M, Nestler EJ. Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens. The Journal of Pharmacology and Experimental Therapeutics. 275: 1671-80. PMID 8531143  1
1995 Fitzgerald LW, Charlton ME, Duman RS, Nestler EJ. Regulation of neuronal nitric oxide synthase by chronic ethanol ingestion. Synapse (New York, N.Y.). 21: 93-5. PMID 8525467 DOI: 10.1002/syn.890210113  1
1995 Rosin DL, Melia K, Knorr AM, Nestler EJ, Roth RH, Duman RS. Chronic imipramine administration alters the activity and phosphorylation state of tyrosine hydroxylase in dopaminergic regions of rat brain. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 12: 113-21. PMID 7779239 DOI: 10.1016/0893-133X(94)00066-9  1
1995 Nestler EJ, Terwilliger RZ, Duman RS. Regulation of endogenous ADP-ribosylation by acute and chronic lithium in rat brain. Journal of Neurochemistry. 64: 2319-24. PMID 7722518  1
1995 Self DW, Nestler EJ. Molecular mechanisms of drug reinforcement and addiction. Annual Review of Neuroscience. 18: 463-95. PMID 7605071 DOI: 10.1146/annurev.ne.18.030195.002335  1
1995 Chen J, Nye HE, Kelz MB, Hiroi N, Nakabeppu Y, Hope BT, Nestler EJ. Regulation of delta FosB and FosB-like proteins by electroconvulsive seizure and cocaine treatments. Molecular Pharmacology. 48: 880-9. PMID 7476919  1
1994 Hope BT, Kelz MB, Duman RS, Nestler EJ. Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4318-28. PMID 8027782  1
1994 Duman RS, Heninger GR, Nestler EJ. Molecular psychiatry. Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity. The Journal of Nervous and Mental Disease. 182: 692-700. PMID 7989913  1
1994 Hope BT, Nye HE, Kelz MB, Self DW, Iadarola MJ, Nakabeppu Y, Duman RS, Nestler EJ. Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron. 13: 1235-44. PMID 7946359 DOI: 10.1016/0896-6273(94)90061-2  1
1994 Self DW, Terwilliger RZ, Nestler EJ, Stein L. Inactivation of Gi and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6239-47. PMID 7931576  1
1993 Nestler EJ, Bergson CM, Gultart X, Hope BT. Regulation of neural gene expression in opiate and cocaine addiction. Nida Research Monograph. 125: 92-116. PMID 8341370  1
1993 Nestler EJ, Hope BT, Widnell KL. Drug addiction: a model for the molecular basis of neural plasticity. Neuron. 11: 995-1006. PMID 8274284 DOI: 10.1016/0896-6273(93)90213-B  1
1993 Vaccarino FM, Hayward MD, Le HN, Hartigan DJ, Duman RS, Nestler EJ. Induction of immediate early genes by cyclic AMP in primary cultures of neurons from rat cerebral cortex. Brain Research. Molecular Brain Research. 19: 76-82. PMID 8103187 DOI: 10.1016/0169-328X(93)90151-E  1
1992 Vaccarino FM, Hayward MD, Nestler EJ, Duman RS, Tallman JF. Differential induction of immediate early genes by excitatory amino acid receptor types in primary cultures of cortical and striatal neurons. Brain Research. Molecular Brain Research. 12: 233-41. PMID 1347632 DOI: 10.1016/0169-328X(92)90089-T  1
1991 Campeau S, Hayward MD, Hope BT, Rosen JB, Nestler EJ, Davis M. Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear. Brain Research. 565: 349-52. PMID 1842702 DOI: 10.1016/0006-8993(91)91669-R  1
1986 Nestler EJ, Greengard P. Synapsin I: a review of its distribution and biological regulation. Progress in Brain Research. 69: 323-39. PMID 3128842  1
1985 Goelz SE, Nestler EJ, Greengard P. Phylogenetic survey of proteins related to synapsin I and biochemical analysis of four such proteins from fish brain. Journal of Neurochemistry. 45: 63-72. PMID 2582092  1
1984 Nestler EJ, Walaas SI, Greengard P. Neuronal phosphoproteins: physiological and clinical implications. Science (New York, N.Y.). 225: 1357-64. PMID 6474180  1
1984 Perdahl E, Adolfsson R, Alafuzoff I, Albert KA, Nestler EJ, Greengard P, Winblad B. Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multi-infarct dementia. Journal of Neural Transmission. 60: 133-41. PMID 6436437 DOI: 10.1007/BF01245030  1
1984 Nestler EJ, Greengard P. Neuron-specific phosphoproteins in mammalian brain. Advances in Cyclic Nucleotide and Protein Phosphorylation Research. 17: 483-8. PMID 6328931  1
1983 Nestler EJ, Greengard P. Protein phosphorylation in the brain. Nature. 305: 583-8. PMID 6312325 DOI: 10.1038/305583a0  1
1982 Nestler EJ, Greengard P. Distribution of protein I and regulation of its state of phosphorylation in the rabbit superior cervical ganglion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 1011-23. PMID 6809906  1
1982 Fried G, Nestler EJ, De Camilli P, Stjärne L, Olson L, Lundberg JM, Hökfelt T, Ouimet CC, Greengard P. Cellular and subcellular localization of protein I in the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. 79: 2717-21. PMID 6806817 DOI: 10.1073/pnas.79.8.2717  1
1982 Nestler EJ, Greengard P. Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglion. Nature. 296: 452-4. PMID 6278329 DOI: 10.1038/296452a0  1
1982 Nestler EJ, Zata M, Greengard P. A diurnal rhythm in pineal protein 1 content mediated by beta-adrenergic neurotransmission. Science (New York, N.Y.). 217: 357-9. PMID 6124039  1
1981 Goelz SE, Nestler EJ, Chehrazi B, Greengard P. Distribution of protein I in mammalian brain as determined by a detergent-based radioimmunoassay. Proceedings of the National Academy of Sciences of the United States of America. 78: 2130-4. PMID 6787599  1
1981 Nestler EJ, Rainbow TC, McEwen BS, Greengard P. Corticosterone increases the amount of protein 1, a neuron-specific phosphoprotein, in rat hippocampus. Science (New York, N.Y.). 212: 1162-4. PMID 6785886  1
1980 Nestler EJ, Greengard P. Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglion. Proceedings of the National Academy of Sciences of the United States of America. 77: 7479-83. PMID 6164062  1
1978 Nestler EJ, Beam KG, Greengard P. Nicotinic cholinergic stimulation increases cyclic GMP levels in vertebrate skeletal muscle. Nature. 275: 451-3. PMID 211436  1
1977 Beam KG, Nestler EJ, Greengard P. Increased cyclic GMP levels associated with contraction in muscle fibres of the giant barnacle. Nature. 267: 534-6. PMID 195221  1
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2018 Kaufman J, Wymbs NF, Montalvo-Ortiz JL, Orr C, Albaugh MD, Althoff R, O'Loughlin K, Holbrook H, Garavan H, Kearney C, Yang BZ, Zhao H, Peña C, Nestler EJ, Lee RS, et al. Methylation in OTX2 and related genes, maltreatment, and depression in children. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30089883 DOI: 10.1038/s41386-018-0157-y  0.28
2017 Yin Z, Machius M, Nestler EJ, Rudenko G. Activator Protein-1: redox switch controlling structure and DNA-binding. Nucleic Acids Research. PMID 28981703 DOI: 10.1093/nar/gkx795  0.2
2001 Nestler EJ, Landsman D. Learning about addiction from the genome. Nature. 409: 834-5. PMID 11237002 DOI: 10.1038/35057015  0.08
2001 Nestler EJ, Olivier B. Overview of the use of transgenic animals in CNS drug discovery. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit5.20. PMID 21965073 DOI: 10.1002/0471141755.ph0520s07  0.04
2016 Nestler EJ. Transgenerational Epigenetic Contributions to Stress Responses: Fact or Fiction? Plos Biology. 14: e1002426. PMID 27015088 DOI: 10.1371/journal.pbio.1002426  0.01
2015 Nestler EJ. Role of the Brain's Reward Circuitry in Depression: Transcriptional Mechanisms. International Review of Neurobiology. 124: 151-70. PMID 26472529 DOI: 10.1016/bs.irn.2015.07.003  0.01
2013 Nestler EJ. The origins of molecular psychiatry. Journal of Molecular Psychiatry. 1: 3. PMID 25408896 DOI: 10.1186/2049-9256-1-3  0.01
2009 Nestler EJ. Epigenetic mechanisms in psychiatry. Biological Psychiatry. 65: 189-90. PMID 19146997 DOI: 10.1016/j.biopsych.2008.10.030  0.01
2008 Nestler EJ. Review. Transcriptional mechanisms of addiction: role of DeltaFosB. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 3245-55. PMID 18640924 DOI: 10.1098/rstb.2008.0067  0.01
2005 Nestler EJ. The neurobiology of cocaine addiction. Science & Practice Perspectives / a Publication of the National Institute On Drug Abuse, National Institutes of Health. 3: 4-10. PMID 18552739  0.01
2005 Nestler EJ. Is there a common molecular pathway for addiction? Nature Neuroscience. 8: 1445-9. PMID 16251986 DOI: 10.1038/nn1578  0.01
2004 Nestler EJ. Molecular mechanisms of drug addiction. Neuropharmacology. 47: 24-32. PMID 15464123 DOI: 10.1016/j.neuropharm.2004.06.031  0.01
2004 Nestler EJ. Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction. Trends in Pharmacological Sciences. 25: 210-8. PMID 15063085 DOI: 10.1016/j.tips.2004.02.005  0.01
2003 Nestler EJ. Obituary: Patricia S. Goldman-Rakic (1937-2003). Nature. 425: 471. PMID 14523433 DOI: 10.1038/425471a  0.01
2002 Nestler EJ. Common molecular and cellular substrates of addiction and memory. Neurobiology of Learning and Memory. 78: 637-47. PMID 12559841  0.01
2002 Nestler EJ. From neurobiology to treatment: progress against addiction. Nature Neuroscience. 5: 1076-9. PMID 12403990 DOI: 10.1038/nn945  0.01
2001 Nestler EJ. Psychogenomics: opportunities for understanding addiction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8324-7. PMID 11606619  0.01
2001 Nestler EJ. Molecular neurobiology of addiction. The American Journal On Addictions / American Academy of Psychiatrists in Alcoholism and Addictions. 10: 201-17. PMID 11579619  0.01
2001 Nestler EJ. Neurobiology. Total recall-the memory of addiction. Science (New York, N.Y.). 292: 2266-7. PMID 11423644 DOI: 10.1126/science.1063024  0.01
2001 Nestler EJ. Molecular basis of long-term plasticity underlying addiction. Nature Reviews. Neuroscience. 2: 119-28. PMID 11252991 DOI: 10.1038/35053570  0.01
2000 Nestler EJ. Genes and addiction. Nature Genetics. 26: 277-81. PMID 11062465 DOI: 10.1038/81570  0.01
1975 Olowo-Okorun MO. Gastrin-like activity in an Indian python. Comparative Biochemistry and Physiology. C: Comparative Pharmacology. 52: 9-10. PMID 208  0.01
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