Susan R. George - Related publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Pharmacology, Neuroscience Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Kong X, Li ZX, Gao YQ, Liu FH, Chen ZZ, Tian HG, Liu TX, Xu YY, Kang ZW. Genome-Wide Identification of Neuropeptides and Their Receptors in an Aphid Endoparasitoid Wasp, . Insects. 12. PMID 34442310 DOI: 10.3390/insects12080745   
2021 Boritzki V, Hübner H, Allikalt A, Gmeiner P, Wöhrl BM. Optimizing the Expression of Human Dopamine Receptors in . International Journal of Molecular Sciences. 22. PMID 34445358 DOI: 10.3390/ijms22168647   
2021 Simpson EH, Gallo EF, Balsam PD, Javitch JA, Kellendonk C. How changes in dopamine D2 receptor levels alter striatal circuit function and motivation. Molecular Psychiatry. PMID 34385603 DOI: 10.1038/s41380-021-01253-4   
2021 Ceyzériat K, Gloria Y, Tsartsalis S, Fossey C, Cailly T, Fabis F, Millet P, Tournier BB. Alterations in dopamine system and in its connectivity with serotonin in a rat model of Alzheimer's disease. Brain Communications. 3: fcab029. PMID 34286270 DOI: 10.1093/braincomms/fcab029   
2021 Condon AF, Robinson BG, Asad N, Dore TM, Tian L, Williams JT. The residence of synaptically released dopamine on D2 autoreceptors. Cell Reports. 36: 109465. PMID 34348146 DOI: 10.1016/j.celrep.2021.109465   
2021 Okimoto R, Ino K, Ishizu K, Takamatsu H, Sakamoto K, Yuyama H, Fuji H, Someya A, Ohtake A, Ishigami T, Masuda N, Takeda M, Kajioka S, Yoshimura N. . The Journal of Pharmacology and Experimental Therapeutics. PMID 34244231 DOI: 10.1124/jpet.121.000709   
2021 Pfeifer P, Sebastian A, Buchholz HG, Kaller CP, Gründer G, Fehr C, Schreckenberger M, Tüscher O. Prefrontal and striatal dopamine D/D receptors correlate with fMRI BOLD activation during stopping. Brain Imaging and Behavior. PMID 34403039 DOI: 10.1007/s11682-021-00491-y   
2021 Stepniewski TM, Mancini A, Ågren R, Torrens-Fontanals M, Semache M, Bouvier M, Sahlholm K, Breton B, Selent J. Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003. PMID 34522296 DOI: 10.1039/d1sc00749a   
2021 Free RB, Cuoco CA, Xie B, Namkung Y, Prabhu VV, Willette BKA, Day MM, Sanchez-Soto M, Lane JR, Laporte SA, Shi L, Allen JE, Sibley DR. Pharmacological characterization of the imipridone anti-cancer drug ONC201 reveals a negative allosteric mechanism of action at the D dopamine receptor. Molecular Pharmacology. PMID 34353882 DOI: 10.1124/molpharm.121.000336   
2021 Gonda X, Tarazi FI. Dopamine D3 Receptors: From Bench to Bedside. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet Lapja = Official Journal of the Hungarian Association of Psychopharmacology. 23: 272-280. PMID 34342419   
2021 Misganaw D. Heteromerization of dopaminergic receptors in the brain: Pharmacological implications. Pharmacological Research. 170: 105600. PMID 33836279 DOI: 10.1016/j.phrs.2021.105600   
2021 Lu S, He X, Yang Z, Chai Z, Zhou S, Wang J, Rehman AU, Ni D, Pu J, Sun J, Zhang J. Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design. Nature Communications. 12: 4721. PMID 34354057 DOI: 10.1038/s41467-021-25020-9   
2021 Reynolds GP. High dose antipsychotic polypharmacy and dopamine partial agonists - time to rethink guidelines? Journal of Psychopharmacology (Oxford, England). 2698811211026456. PMID 34256637 DOI: 10.1177/02698811211026456   
2021 Nobrega JN, Raymond R, Rajji TK, Pollock BG. A calcium fluorescence assay for quantification of cholinergic receptor activity of clinical drugs in serum - comparison with radioactive methods. Journal of Pharmacological and Toxicological Methods. 107118. PMID 34481920 DOI: 10.1016/j.vascn.2021.107118   
2021 Wang F, Cai W, Shi W, Wu H, Shen Q, He Y, Cui S, An L. Single molecule real-time sequencing revealing novel insights on the response to estrogen and androgen exposure in freshwater snails. Aquatic Toxicology (Amsterdam, Netherlands). 239: 105953. PMID 34521059 DOI: 10.1016/j.aquatox.2021.105953   
2021 Harb A, Vogel N, Shaib A, Becherer U, Bruns D, Mohrmann R. Auxiliary Subunits Regulate the Dendritic Turnover of AMPA Receptors in Mouse Hippocampal Neurons. Frontiers in Molecular Neuroscience. 14: 728498. PMID 34497491 DOI: 10.3389/fnmol.2021.728498   
2021 Eguchi A, Ueki A, Hoshiyama J, Kuwata K, Chikaoka Y, Kawamura T, Nagatoishi S, Tsumoto K, Ueki R, Sando S. A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells. Jacs Au. 1: 578-585. PMID 34467321 DOI: 10.1021/jacsau.0c00121   
2021 Papke RL, Horenstein NA. Therapeutic Targeting of 7 Nicotinic Acetylcholine Receptors. Pharmacological Reviews. 73: 1118-1149. PMID 34301823 DOI: 10.1124/pharmrev.120.000097   
2021 Turu G, Soltész-Katona E, Tóth AD, Juhász C, Cserző M, Misák Á, Balla A, Caron MG, Hunyady L. Biased Coupling to β-Arrestin of Two Common Variants of the CB Cannabinoid Receptor. Frontiers in Endocrinology. 12: 714561. PMID 34484125 DOI: 10.3389/fendo.2021.714561   
2021 Yang W, Nan H, Xu Z, Huang Z, Chen S, Li J, Li J, Yang H. DNA-Templated Glycan Labeling for Monitoring Receptor Spatial Distribution in Living Cells. Analytical Chemistry. PMID 34474560 DOI: 10.1021/acs.analchem.1c01815   
2021 Budzinski J, Maschauer S, Kobayashi H, Couvineau P, Vogt H, Gmeiner P, Roggenhofer A, Prante O, Bouvier M, Weikert D. Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer. Communications Biology. 4: 1062. PMID 34508168 DOI: 10.1038/s42003-021-02574-4   
2021 Gonias SL. Plasminogen activator receptor assemblies in cell-signaling, innate immunity, and inflammation. American Journal of Physiology. Cell Physiology. PMID 34406905 DOI: 10.1152/ajpcell.00269.2021   
2021 Giubilaro J, Schuetz DA, Stepniewski TM, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, et al. Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen. Nature Communications. 12: 4688. PMID 34344896 DOI: 10.1038/s41467-021-24968-y   
2021 Lenglez S, Sablon A, Fénelon G, Boland A, Deleuze JF, Boutoleau-Bretonnière C, Nicolas G, Demoulin JB. Distinct functional classes of PDGFRB pathogenic variants in primary familial brain calcification. Human Molecular Genetics. PMID 34494111 DOI: 10.1093/hmg/ddab258   
2021 Haider S, Pandey P, Reddy CR, Lambert JA, Chittiboyina AG. Novel Machaeriol Analogues as Modulators of Cannabinoid Receptors: Structure-Activity Relationships of (+)-Hexahydrocannabinoids and Their Isoform Selectivities. Acs Omega. 6: 20408-20421. PMID 34395989 DOI: 10.1021/acsomega.1c02413   
2021 Byrne KF, Pal A, Curtin JF, Stephens JC, Kinsella GK. G-protein-coupled receptors as therapeutic targets for glioblastoma. Drug Discovery Today. PMID 34271165 DOI: 10.1016/j.drudis.2021.07.008   
2021 Desroches-Castan A, Tillet E, Bouvard C, Bailly S. BMP9 and BMP10: two close vascular quiescence partners that stand out. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 34240497 DOI: 10.1002/dvdy.395   
2021 Lommen J, Detken J, Harr K, von Gall C, Ali AAH. Analysis of Spatial and Temporal Distribution of Purinergic P2 Receptors in the Mouse Hippocampus. International Journal of Molecular Sciences. 22. PMID 34360844 DOI: 10.3390/ijms22158078   
2021 Leach DA, Brooke GN, Bevan CL. Roles of steroid receptors in the lung and COVID-19. Essays in Biochemistry. PMID 34328182 DOI: 10.1042/EBC20210005   
2021 Gonzalez CU, Carrillo E, Berka V, Jayaraman V. Structural Arrangement Produced by Concanavalin A Binding to Homomeric GluK2 Receptors. Membranes. 11. PMID 34436376 DOI: 10.3390/membranes11080613   
2021 Arellano-Saab A, Bunsick M, Al Galib H, Zhao W, Schuetz S, Bradley JM, Xu Z, Adityani C, Subha A, McKay H, de Saint Germain A, Boyer FD, McErlean CSP, Toh S, McCourt P, et al. Three mutations repurpose a plant karrikin receptor to a strigolactone receptor. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34301902 DOI: 10.1073/pnas.2103175118   
2021 van Aalst E, Wylie BJ. Cholesterol Is a Dose-Dependent Positive Allosteric Modulator of CCR3 Ligand Affinity and G Protein Coupling. Frontiers in Molecular Biosciences. 8: 724603. PMID 34490352 DOI: 10.3389/fmolb.2021.724603   
2021 Sharma A, Kumar GA, Chattopadhyay A. Late Endosomal/Lysosomal Accumulation of a Neurotransmitter Receptor in a Cellular Model of Smith-Lemli-Opitz Syndrome. Traffic (Copenhagen, Denmark). PMID 34418249 DOI: 10.1111/tra.12811   
2021 Morimoto S, Morishima N, Watanabe D, Kato Y, Shibata N, Ichihara A. Immunohistochemistry for (Pro)renin Receptor in Humans. International Journal of Endocrinology. 2021: 8828610. PMID 34367278 DOI: 10.1155/2021/8828610   
2021 Avoli M, Lévesque M. Gabab Receptors: Are They Missing In Action In Focal Epilepsy Research? Current Neuropharmacology. PMID 34429053 DOI: 10.2174/1570159X19666210823102332   
2021 Dahlén A, Zarei M, Melgoza A, Wagle M, Guo S. THC-induced behavioral stereotypy in zebrafish as a model of psychosis-like behavior. Scientific Reports. 11: 15693. PMID 34344922 DOI: 10.1038/s41598-021-95016-4   
2021 Benham RS, Choi C, Hodgson NW, Hewage NB, Kastli R, Donahue RJ, Muschamp JW, Engin E, Carlezon WA, Hensch TK, Rudolph U. α2-containing γ-aminobutyric acid type A receptors promote stress resiliency in male mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34408277 DOI: 10.1038/s41386-021-01144-w   
2021 Sisignano M, Fischer MJM, Geisslinger G. Proton-Sensing GPCRs in Health and Disease. Cells. 10. PMID 34440817 DOI: 10.3390/cells10082050   
2021 Li Y, Wang X, Lu L, Wang M, Zhai Y, Tai X, Dilimulati D, Lei X, Xu J, Zhang C, Fu Y, Qu S, Li Q, Zhang C. Identification of novel GPCR partners of the central melanocortin signaling. Molecular Metabolism. 101317. PMID 34400348 DOI: 10.1016/j.molmet.2021.101317   
2021 Ago Y, Asano S, Hashimoto H, Waschek JA. Probing the Microduplication Linkage to Schizophrenia in Animal and Cellular Models. Frontiers in Neuroscience. 15: 717490. PMID 34366784 DOI: 10.3389/fnins.2021.717490   
2021 Deganutti G, Atanasio S, Rujan RM, Sexton PM, Wootten D, Reynolds CA. Exploring Ligand Binding to Calcitonin Gene-Related Peptide Receptors. Frontiers in Molecular Biosciences. 8: 720561. PMID 34513925 DOI: 10.3389/fmolb.2021.720561   
2021 Huang SJ, Zuo MT, Qi XJ, Huang CY, Liu ZY. Phosphoproteomics reveals NMDA receptor-mediated excitotoxicity as a key signaling pathway in the toxicity of gelsenicine. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 112507. PMID 34389372 DOI: 10.1016/j.fct.2021.112507   
2021 Hur J, Kang ES, Hwang JS, Lee WJ, Won JP, Lee HG, Kim E, Seo HG. Peroxisome proliferator-activated receptor-δ-mediated upregulation of catalase helps to reduce ultraviolet B-induced cellular injury in dermal fibroblasts. Journal of Dermatological Science. PMID 34420848 DOI: 10.1016/j.jdermsci.2021.08.003   
2021 Hodge MX, Henriquez AR, Kodavanti UP. Adrenergic and Glucocorticoid Receptors in the Pulmonary Health Effects of Air Pollution. Toxics. 9. PMID 34200050 DOI: 10.3390/toxics9060132   
2021 Dodat F, Mader S, Lévesque D. Minireview: what is known about SUMOylation among NR4A family members? Journal of Molecular Biology. 167212. PMID 34437889 DOI: 10.1016/j.jmb.2021.167212   
2021 Subramanian S, Ravichandran M. Orexin receptors: Targets and applications. Fundamental & Clinical Pharmacology. PMID 34464995 DOI: 10.1111/fcp.12723   
2021 Jain S, Jacobson KA. Purinergic Signaling in Liver Pathophysiology. Frontiers in Endocrinology. 12: 718429. PMID 34456873 DOI: 10.3389/fendo.2021.718429   
2021 Tao XX, Wang B, Zuo SK, Yu Y. [Identification of mouse lines with HA-tagged prostaglandin receptors]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 73: 559-570. PMID 34405212   
2021 Haubrich J, Font J, Quast RB, Goupil-Lamy A, Scholler P, Nevoltris D, Acher F, Chames P, Rondard P, Prézeau L, Pin JP. A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34385321 DOI: 10.1073/pnas.2105848118   
2021 Pivonello R, Bancos I, Feelders RA, Kargi AY, Kerr JM, Gordon MB, Mariash CN, Terzolo M, Ellison N, Moraitis AG. Relacorilant, a Selective Glucocorticoid Receptor Modulator, Induces Clinical Improvements in Patients With Cushing Syndrome: Results From A Prospective, Open-Label Phase 2 Study. Frontiers in Endocrinology. 12: 662865. PMID 34335465 DOI: 10.3389/fendo.2021.662865