| Year |
Citation |
Score |
| 2021 |
Needham PG, Goeckeler-Fried JL, Zhang C, Sun Z, Wetzel AR, Bertrand CA, Brodsky JL. SLC26A9 is selected for endoplasmic reticulum associated degradation (ERAD) via Hsp70-dependent targeting of the soluble STAS domain. The Biochemical Journal. 478: 4203-4220. PMID 34821356 DOI: 10.1042/BCJ20210644 |
0.355 |
|
| 2019 |
Cui Y, Parashar S, Zahoor M, Needham PG, Mari M, Zhu M, Chen S, Ho HC, Reggiori F, Farhan H, Brodsky JL, Ferro-Novick S. A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation. Science (New York, N.Y.). 365: 53-60. PMID 31273116 DOI: 10.1126/Science.Aau9263 |
0.356 |
|
| 2019 |
Needham PG, Guerriero CJ, Brodsky JL. Chaperoning Endoplasmic Reticulum-Associated Degradation (ERAD) and Protein Conformational Diseases. Cold Spring Harbor Perspectives in Biology. PMID 30670468 DOI: 10.1101/Cshperspect.A033928 |
0.432 |
|
| 2018 |
Chiang AN, Liang M, Dominguez-Meijide A, Masaracchia C, Goeckeler-Fried JL, Mazzone CS, Newhouse DW, Kendsersky NM, Yates ME, Manos-Turvey A, Needham PG, Outeiro TF, Wipf P, Brodsky JL. Synthesis and evaluation of esterified Hsp70 agonists in cellular models of protein aggregation and folding. Bioorganic & Medicinal Chemistry. PMID 30528127 DOI: 10.1016/J.Bmc.2018.11.011 |
0.399 |
|
| 2018 |
Hager NA, Krasowski CJ, Mackie TD, Kolb AR, Needham PG, Augustine AA, Dempsey A, Szent-Gyorgyi C, Bruchez MP, Bain DJ, Kwiatkowski AV, O'Donnell AF, Brodsky JL. Select α-arrestins control cell-surface abundance of the mammalian Kir2.1 potassium channel in a yeast model. The Journal of Biological Chemistry. PMID 29784874 DOI: 10.1074/Jbc.Ra117.001293 |
0.364 |
|
| 2017 |
Ye Z, Needham PG, Estabrooks SK, Whitaker SK, Garcia BL, Misra S, Brodsky JL, Camacho CJ. Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase. Scientific Reports. 7: 1789. PMID 28496195 DOI: 10.1038/S41598-017-01880-4 |
0.362 |
|
| 2016 |
Manos-Turvey A, Al-Ashtal HA, Needham PG, Hartline CB, Prichard MN, Wipf P, Brodsky JL. Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members. Bioorganic & Medicinal Chemistry Letters. PMID 27624078 DOI: 10.1016/J.Bmcl.2016.08.080 |
0.304 |
|
| 2015 |
Needham PG, Patel HJ, Chiosis G, Thibodeau PH, Brodsky JL. Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions. Journal of Molecular Biology. PMID 25913688 DOI: 10.1016/J.Jmb.2015.04.010 |
0.443 |
|
| 2015 |
Buck TM, Jordan R, Lyons-Weiler J, Adelman JL, Needham PG, Kleyman TR, Brodsky JL. Expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiae. Physiological Genomics. 47: 198-214. PMID 25759377 DOI: 10.1152/Physiolgenomics.00101.2014 |
0.428 |
|
| 2014 |
Surlow BA, Cooley BM, Needham PG, Brodsky JL, Patton-Vogt J. Loss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylation. The Journal of Biological Chemistry. 289: 31591-604. PMID 25258318 DOI: 10.1074/Jbc.M114.581157 |
0.399 |
|
| 2014 |
Kolb AR, Needham PG, Rothenberg C, Guerriero CJ, Welling PA, Brodsky JL. ESCRT regulates surface expression of the Kir2.1 potassium channel. Molecular Biology of the Cell. 25: 276-89. PMID 24227888 DOI: 10.1091/Mbc.E13-07-0394 |
0.376 |
|
| 2013 |
Needham PG, Brodsky JL. How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: the early history of ERAD. Biochimica Et Biophysica Acta. 1833: 2447-57. PMID 23557783 DOI: 10.1016/J.Bbamcr.2013.03.018 |
0.39 |
|
| 2013 |
Donnelly BF, Needham PG, Snyder AC, Roy A, Khadem S, Brodsky JL, Subramanya AR. Hsp70 and Hsp90 multichaperone complexes sequentially regulate thiazide-sensitive cotransporter endoplasmic reticulum-associated degradation and biogenesis. The Journal of Biological Chemistry. 288: 13124-35. PMID 23482560 DOI: 10.1074/Jbc.M113.455394 |
0.438 |
|
| 2011 |
Needham PG, Mikoluk K, Dhakarwal P, Khadem S, Snyder AC, Subramanya AR, Brodsky JL. The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation. The Journal of Biological Chemistry. 286: 43611-21. PMID 22027832 DOI: 10.1074/Jbc.M111.288928 |
0.421 |
|
| 2011 |
Botha M, Chiang AN, Needham PG, Stephens LL, Hoppe HC, Külzer S, Przyborski JM, Lingelbach K, Wipf P, Brodsky JL, Shonhai A, Blatch GL. Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock. Cell Stress & Chaperones. 16: 389-401. PMID 21191678 DOI: 10.1007/S12192-010-0250-6 |
0.376 |
|
| 2008 |
Needham PG, Masison DC. Prion-impairing mutations in Hsp70 chaperone Ssa1: effects on ATPase and chaperone activities. Archives of Biochemistry and Biophysics. 478: 167-74. PMID 18706386 DOI: 10.1016/J.Abb.2008.07.023 |
0.372 |
|
| 2007 |
Dignam SS, Collaco RF, Bieszczad J, Needham P, Trempe JP, Dignam JD. Coupled ATP and DNA binding of adeno-associated virus Rep40 helicase. Biochemistry. 46: 568-76. PMID 17209567 DOI: 10.1021/Bi061762V |
0.314 |
|
| 2007 |
Bevington JM, Needham PG, Verrill KC, Collaco RF, Basrur V, Trempe JP. Adeno-associated virus interactions with B23/Nucleophosmin: identification of sub-nucleolar virion regions. Virology. 357: 102-13. PMID 16959286 DOI: 10.1016/J.Virol.2006.07.050 |
0.356 |
|
| 2006 |
Needham PG, Trumbly RJ. In vitro characterization of the Mig1 repressor from Saccharomyces cerevisiae reveals evidence for monomeric and higher molecular weight forms. Yeast (Chichester, England). 23: 1151-66. PMID 17133623 DOI: 10.1002/Yea.1429 |
0.508 |
|
| 2006 |
Needham PG, Casper JM, Kalman-Maltese V, Verrill K, Dignam JD, Trempe JP. Adeno-associated virus rep protein-mediated inhibition of transcription of the adenovirus major late promoter in vitro. Journal of Virology. 80: 6207-17. PMID 16775308 DOI: 10.1128/Jvi.00183-06 |
0.44 |
|
| Show low-probability matches. |