| Year |
Citation |
Score |
| 2024 |
Singer RA, Rajchin V, Park K, Heintz N, Darnell RB. Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation. Biorxiv : the Preprint Server For Biology. PMID 39185177 DOI: 10.1101/2024.08.13.607210 |
0.739 |
|
| 2024 |
Hacisuleyman E, Hale CR, Noble N, Luo JD, Fak JJ, Saito M, Chen J, Weissman JS, Darnell RB. Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding. Nature Neuroscience. PMID 38589584 DOI: 10.1038/s41593-024-01615-5 |
0.329 |
|
| 2024 |
Saito Y, Yang Y, Saito M, Park CY, Funato K, Tabar V, Darnell RB. NOVA1 acts as an oncogenic RNA-binding protein to regulate cholesterol homeostasis in human glioblastoma cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314695121. PMID 38416679 DOI: 10.1073/pnas.2314695121 |
0.429 |
|
| 2023 |
Irmady K, Hale CR, Qadri R, Fak J, Simelane S, Carroll T, Przedborski S, Darnell RB. Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson's disease. Nature Communications. 14: 3956. PMID 37407548 DOI: 10.1038/s41467-023-39652-6 |
0.749 |
|
| 2023 |
Ibrahim LA, Wamsley B, Alghamdi N, Yusuf N, Sevier E, Hairston A, Sherer M, Jaglin XH, Xu Q, Guo L, Jamayran AK, Favuzzi E, Yuan Y, Dimidschstein J, Darnell RB, et al. Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing. Elife. 12. PMID 37347149 DOI: 10.7554/eLife.86842 |
0.334 |
|
| 2023 |
Tajima Y, Ito K, Yuan Y, Frank MO, Saito Y, Darnell RB. NOVA1 acts on Impact to regulate hypothalamic function and translation in inhibitory neurons. Cell Reports. 42: 112050. PMID 36716149 DOI: 10.1016/j.celrep.2023.112050 |
0.601 |
|
| 2022 |
Saito Y, Hawley BR, Puno MR, Sarathy SN, Lima CD, Jaffrey SR, Darnell RB, Keeney S, Jain D. YTHDC2 control of gametogenesis requires helicase activity but not mA binding. Genes & Development. 36: 180-194. PMID 35058317 DOI: 10.1101/gad.349190.121 |
0.352 |
|
| 2022 |
Darnell RB. Corrigendum: CLIP (Cross-Linking and Immunoprecipitation) Identification of RNAs Bound by a Specific Protein. Cold Spring Harbor Protocols. 2022: pdb.corr107811. PMID 34983862 DOI: 10.1101/pdb.corr107811 |
0.351 |
|
| 2021 |
Hale CR, Sawicka K, Mora K, Fak JJ, Kang JJ, Cutrim P, Cialowicz K, Carroll TS, Darnell RB. FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons. Elife. 10. PMID 34939924 DOI: 10.7554/eLife.71892 |
0.332 |
|
| 2021 |
Knupp D, Cooper DA, Saito Y, Darnell RB, Miura P. NOVA2 regulates neural circRNA biogenesis. Nucleic Acids Research. PMID 34157123 DOI: 10.1093/nar/gkab523 |
0.49 |
|
| 2021 |
Park CY, Zhou J, Wong AK, Chen KM, Theesfeld CL, Darnell RB, Troyanskaya OG. Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk. Nature Genetics. PMID 33462483 DOI: 10.1038/s41588-020-00761-3 |
0.356 |
|
| 2019 |
Sawicka K, Hale CR, Park CY, Fak JJ, Gresack JE, Van Driesche SJ, Kang JJ, Darnell JC, Darnell RB. FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory. Elife. 8. PMID 31860442 DOI: 10.7554/eLife.46919 |
0.361 |
|
| 2018 |
Saito Y, Yuan Y, Zucker-Scharff I, Fak JJ, Jereb S, Tajima Y, Licatalosi DD, Darnell RB. Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function. Neuron. PMID 30638744 DOI: 10.1016/j.neuron.2018.12.019 |
0.824 |
|
| 2018 |
Darnell JC, Mele A, Hung KYS, Darnell RB. Mapping of In Vivo RNA-Binding Sites by Ultraviolet (UV)-Cross-Linking Immunoprecipitation (CLIP). Cold Spring Harbor Protocols. 2018: pdb.top097931. PMID 30510132 DOI: 10.1101/pdb.top097931 |
0.393 |
|
| 2018 |
Darnell JC, Mele A, Hung KYS, Darnell RB. 3'-Linker Ligation and Size Selection by SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). Cold Spring Harbor Protocols. 2018: pdb.prot097964. PMID 30510127 DOI: 10.1101/pdb.prot097964 |
0.326 |
|
| 2018 |
Darnell JC, Mele A, Hung KYS, Darnell RB. Immunoprecipitation and SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP). Cold Spring Harbor Protocols. 2018: pdb.prot097956. PMID 30510126 DOI: 10.1101/pdb.prot097956 |
0.308 |
|
| 2018 |
Yuan Y, Xie S, Darnell JC, Darnell AJ, Saito Y, Phatnani H, Murphy EA, Zhang C, Maniatis T, Darnell RB. Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons. Genome Biology. 19: 117. PMID 30111345 DOI: 10.1186/S13059-018-1493-2 |
0.61 |
|
| 2018 |
Ule J, Hwang HW, Darnell RB. The Future of Cross-Linking and Immunoprecipitation (CLIP). Cold Spring Harbor Perspectives in Biology. 10. PMID 30068528 DOI: 10.1101/Cshperspect.A032243 |
0.649 |
|
| 2018 |
Moore MJ, Blachere NE, Fak JJ, Park CY, Sawicka K, Parveen S, Zucker-Scharff I, Moltedo B, Rudensky AY, Darnell RB. ZFP36 RNA-binding proteins restrain T-cell activation and anti-viral immunity. Elife. 7. PMID 29848443 DOI: 10.7554/Elife.33057 |
0.787 |
|
| 2018 |
Jereb S, Hwang HW, Van Otterloo E, Govek EE, Fak JJ, Yuan Y, Hatten ME, Darnell RB. Differential 3' processing of specific transcripts expands regulatory and protein diversity across neuronal cell types. Elife. 7. PMID 29578408 DOI: 10.7554/Elife.34042 |
0.361 |
|
| 2018 |
Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ. Elavl3 is essential for the maintenance of Purkinje neuron axons. Scientific Reports. 8: 2722. PMID 29426875 DOI: 10.1038/S41598-018-21130-5 |
0.338 |
|
| 2017 |
Blachère NE, Orange DE, Gantman EC, Santomasso BD, Couture GC, Ramirez-Montagut T, Fak J, O'Donovan KJ, Ru Z, Parveen S, Frank MO, Moore MJ, Darnell RB. T cells presenting viral antigens or autoantigens induce cytotoxic T cell anergy. Jci Insight. 2. PMID 29093272 DOI: 10.1172/jci.insight.96173 |
0.658 |
|
| 2017 |
Hwang HW, Saito Y, Park CY, Blachère NE, Tajima Y, Fak JJ, Zucker-Scharff I, Darnell RB. cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation. Neuron. 95: 1334-1349.e5. PMID 28910620 DOI: 10.1016/J.Neuron.2017.08.024 |
0.798 |
|
| 2017 |
Korb E, Herre M, Zucker-Scharff I, Gresack J, Allis CD, Darnell RB. Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. Cell. PMID 28823556 DOI: 10.1016/J.Cell.2017.07.033 |
0.778 |
|
| 2016 |
Leggere JC, Saito Y, Darnell RB, Tessier-Lavigne M, Junge HJ, Chen Z. NOVA regulate Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. Elife. 5. PMID 27223328 DOI: 10.7554/Elife.14264 |
0.328 |
|
| 2016 |
Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB. NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 5. PMID 27223325 DOI: 10.7554/Elife.14371 |
0.775 |
|
| 2016 |
Hwang HW, Park CY, Goodarzi H, Fak JJ, Mele A, Moore MJ, Saito Y, Darnell RB. PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage. Cell Reports. PMID 27050522 DOI: 10.1016/J.Celrep.2016.03.023 |
0.33 |
|
| 2016 |
Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB. Erratum: Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis. Nature Protocols. 11: 616. PMID 26914319 DOI: 10.1038/nprot0316-616c |
0.596 |
|
| 2016 |
Scheckel C, Drapeau E, Frias MA, Park CY, Fak J, Zucker-Scharff I, Kou Y, Haroutunian V, Ma'ayan A, Buxbaum JD, Darnell RB. Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain. Elife. 5. PMID 26894958 DOI: 10.7554/Elife.10421 |
0.818 |
|
| 2016 |
Chen BR, Robine N, Wrzeszczynski K, Vacic V, Emde AK, Arora K, Shah M, Grabowska EA, Felice V, Dikoglu E, Reeves C, Frank M, Jobanputra V, Zody MC, Bloom T, ... Darnell R, et al. Abstract 4498: RNA-Seq in the NYGC GBM Clinical Outcomes Pilot Study Cancer Research. 76: 4498-4498. DOI: 10.1158/1538-7445.Am2016-4498 |
0.439 |
|
| 2015 |
Ke S, Alemu EA, Mertens C, Gantman EC, Fak JJ, Mele A, Haripal B, Zucker-Scharff I, Moore MJ, Park CY, Vågbø CB, Kuśnierczyk A, Klungland A, Darnell JE, Darnell RB. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes & Development. PMID 26404942 DOI: 10.1101/Gad.269415.115 |
0.759 |
|
| 2015 |
Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A. Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP. Proceedings of the National Academy of Sciences of the United States of America. 112: E5391-400. PMID 26374839 DOI: 10.1073/Pnas.1515737112 |
0.372 |
|
| 2015 |
Korb E, Herre M, Zucker-Scharff I, Darnell RB, Allis CD. BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice. Nature Neuroscience. 18: 1464-73. PMID 26301327 DOI: 10.1038/Nn.4095 |
0.788 |
|
| 2014 |
Weyn-Vanhentenryck SM, Mele A, Yan Q, Sun S, Farny N, Zhang Z, Xue C, Herre M, Silver PA, Zhang MQ, Krainer AR, Darnell RB, Zhang C. HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism. Cell Reports. 6: 1139-52. PMID 24613350 DOI: 10.1016/J.Celrep.2014.02.005 |
0.757 |
|
| 2014 |
Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB. Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis. Nature Protocols. 9: 263-93. PMID 24407355 DOI: 10.1038/Nprot.2014.012 |
0.62 |
|
| 2013 |
Darnell RB. RNA protein interaction in neurons. Annual Review of Neuroscience. 36: 243-70. PMID 23701460 DOI: 10.1146/annurev-neuro-062912-114322 |
0.432 |
|
| 2013 |
Zhang C, Lee KY, Swanson MS, Darnell RB. Prediction of clustered RNA-binding protein motif sites in the mammalian genome. Nucleic Acids Research. 41: 6793-807. PMID 23685613 DOI: 10.1093/Nar/Gkt421 |
0.582 |
|
| 2013 |
Poulos MG, Batra R, Li M, Yuan Y, Zhang C, Darnell RB, Swanson MS. Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice. Human Molecular Genetics. 22: 3547-58. PMID 23660517 DOI: 10.1093/Hmg/Ddt209 |
0.559 |
|
| 2013 |
Eom T, Zhang C, Wang H, Lay K, Fak J, Noebels JL, Darnell RB. NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Elife. 2: e00178. PMID 23359859 DOI: 10.7554/Elife.00178 |
0.658 |
|
| 2012 |
Darnell R. CLIP (cross-linking and immunoprecipitation) identification of RNAs bound by a specific protein. Cold Spring Harbor Protocols. 2012: 1146-60. PMID 23118367 DOI: 10.1101/Pdb.Prot072132 |
0.508 |
|
| 2012 |
Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, Yoo J, Herre M, Okano H, Noebels JL, Darnell RB. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 75: 1067-80. PMID 22998874 DOI: 10.1016/J.Neuron.2012.07.009 |
0.747 |
|
| 2012 |
Charizanis K, Lee KY, Batra R, Goodwin M, Zhang C, Yuan Y, Shiue L, Cline M, Scotti MM, Xia G, Kumar A, Ashizawa T, Clark HB, Kimura T, Takahashi MP, ... ... Darnell RB, et al. Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy. Neuron. 75: 437-50. PMID 22884328 DOI: 10.1016/J.Neuron.2012.05.029 |
0.596 |
|
| 2012 |
Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB. Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Genes & Development. 26: 1626-42. PMID 22802532 DOI: 10.1101/Gad.191338.112 |
0.648 |
|
| 2011 |
Darnell JC, Van Driesche SJ, Zhang C, Hung KY, Mele A, Fraser CE, Stone EF, Chen C, Fak JJ, Chi SW, Licatalosi DD, Richter JD, Darnell RB. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell. 146: 247-61. PMID 21784246 DOI: 10.1016/J.Cell.2011.06.013 |
0.66 |
|
| 2011 |
Teplova M, Malinina L, Darnell JC, Song J, Lu M, Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB, Patel DJ. Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. Structure (London, England : 1993). 19: 930-44. PMID 21742260 DOI: 10.1016/J.Str.2011.05.002 |
0.449 |
|
| 2011 |
Zhang C, Darnell RB. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data. Nature Biotechnology. 29: 607-14. PMID 21633356 DOI: 10.1038/Nbt.1873 |
0.624 |
|
| 2011 |
Kakumoto K, Miyazaki T, Watanabe M, Darnell R, Okano H, Okano H. The maintenance of Purkinje axons by an RNA-binding protein HuC in adult cerebellum Neuroscience Research. 71: e95-e96. DOI: 10.1016/J.Neures.2011.07.410 |
0.43 |
|
| 2010 |
Darnell RB. HITS-CLIP: panoramic views of protein-RNA regulation in living cells. Wiley Interdisciplinary Reviews. Rna. 1: 266-86. PMID 21935890 DOI: 10.1002/wrna.31 |
0.401 |
|
| 2010 |
Allen SE, Darnell RB, Lipscombe D. The neuronal splicing factor Nova controls alternative splicing in N-type and P-type CaV2 calcium channels. Channels (Austin, Tex.). 4: 483-9. PMID 21150296 DOI: 10.4161/chan.4.6.12868 |
0.401 |
|
| 2010 |
Darnell RB. RNA regulation in neurologic disease and cancer. Cancer Research and Treatment : Official Journal of Korean Cancer Association. 42: 125-9. PMID 20948916 DOI: 10.4143/crt.2010.42.3.125 |
0.301 |
|
| 2010 |
Yano M, Hayakawa-Yano Y, Mele A, Darnell RB. Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron. 66: 848-58. PMID 20620871 DOI: 10.1016/j.neuron.2010.05.007 |
0.394 |
|
| 2010 |
Zhang C, Frias MA, Mele A, Ruggiu M, Eom T, Marney CB, Wang H, Licatalosi DD, Fak JJ, Darnell RB. Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls. Science (New York, N.Y.). 329: 439-43. PMID 20558669 DOI: 10.1126/Science.1191150 |
0.627 |
|
| 2010 |
Racca C, Gardiol A, Eom T, Ule J, Triller A, Darnell RB. The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite. Frontiers in Neural Circuits. 4: 5. PMID 20407637 DOI: 10.3389/Neuro.04.005.2010 |
0.696 |
|
| 2010 |
O'Donovan KJ, Diedler J, Couture GC, Fak JJ, Darnell RB. The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells. Plos One. 5: e10045. PMID 20383333 DOI: 10.1371/Journal.Pone.0010045 |
0.682 |
|
| 2010 |
Licatalosi DD, Darnell RB. RNA processing and its regulation: global insights into biological networks. Nature Reviews. Genetics. 11: 75-87. PMID 20019688 DOI: 10.1038/nrg2673 |
0.39 |
|
| 2009 |
Zang JB, Nosyreva ED, Spencer CM, Volk LJ, Musunuru K, Zhong R, Stone EF, Yuva-Paylor LA, Huber KM, Paylor R, Darnell JC, Darnell RB. A mouse model of the human Fragile X syndrome I304N mutation. Plos Genetics. 5: e1000758. PMID 20011099 DOI: 10.1371/journal.pgen.1000758 |
0.346 |
|
| 2009 |
Darnell JC, Fraser CE, Mostovetsky O, Darnell RB. Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Human Molecular Genetics. 18: 3164-77. PMID 19487368 DOI: 10.1093/hmg/ddp255 |
0.361 |
|
| 2008 |
Jensen KB, Darnell RB. CLIP: crosslinking and immunoprecipitation of in vivo RNA targets of RNA-binding proteins. Methods in Molecular Biology (Clifton, N.J.). 488: 85-98. PMID 18982285 DOI: 10.1007/978-1-60327-475-3_6 |
0.401 |
|
| 2008 |
Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, Darnell JC, Darnell RB. HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature. 456: 464-9. PMID 18978773 DOI: 10.1038/nature07488 |
0.676 |
|
| 2007 |
Ule J, Darnell RB. Functional and mechanistic insights from genome-wide studies of splicing regulation in the brain. Advances in Experimental Medicine and Biology. 623: 148-60. PMID 18380345 |
0.697 |
|
| 2007 |
Jelen N, Ule J, Zivin M, Darnell RB. Evolution of Nova-dependent splicing regulation in the brain. Plos Genetics. 3: 1838-47. PMID 17937501 DOI: 10.1371/journal.pgen.0030173 |
0.617 |
|
| 2006 |
Darnell RB. Developing global insight into RNA regulation. Cold Spring Harbor Symposia On Quantitative Biology. 71: 321-7. PMID 17381312 DOI: 10.1101/sqb.2006.71.002 |
0.444 |
|
| 2006 |
Ule J, Stefani G, Mele A, Ruggiu M, Wang X, Taneri B, Gaasterland T, Blencowe BJ, Darnell RB. An RNA map predicting Nova-dependent splicing regulation. Nature. 444: 580-6. PMID 17065982 DOI: 10.1038/Nature05304 |
0.744 |
|
| 2006 |
Ule J, Darnell RB. RNA binding proteins and the regulation of neuronal synaptic plasticity. Current Opinion in Neurobiology. 16: 102-10. PMID 16418001 DOI: 10.1016/j.conb.2006.01.003 |
0.668 |
|
| 2006 |
Ule J, Darnell R. [S18]: RNA regulation and modular control of the neuronal synapse International Journal of Developmental Neuroscience. 24: 479-479. DOI: 10.1016/j.ijdevneu.2006.09.023 |
0.366 |
|
| 2005 |
Ule J, Jensen K, Mele A, Darnell RB. CLIP: a method for identifying protein-RNA interaction sites in living cells. Methods (San Diego, Calif.). 37: 376-86. PMID 16314267 DOI: 10.1016/j.ymeth.2005.07.018 |
0.649 |
|
| 2005 |
Huang CS, Shi SH, Ule J, Ruggiu M, Barker LA, Darnell RB, Jan YN, Jan LY. Common molecular pathways mediate long-term potentiation of synaptic excitation and slow synaptic inhibition. Cell. 123: 105-18. PMID 16213216 DOI: 10.1016/J.Cell.2005.07.033 |
0.552 |
|
| 2005 |
Darnell JC, Mostovetsky O, Darnell RB. FMRP RNA targets: identification and validation. Genes, Brain, and Behavior. 4: 341-9. PMID 16098133 DOI: 10.1111/j.1601-183X.2005.00144.x |
0.4 |
|
| 2005 |
Ule J, Ule A, Spencer J, Williams A, Hu JS, Cline M, Wang H, Clark T, Fraser C, Ruggiu M, Zeeberg BR, Kane D, Weinstein JN, Blume J, Darnell RB. Nova regulates brain-specific splicing to shape the synapse. Nature Genetics. 37: 844-52. PMID 16041372 DOI: 10.1038/Ng1610 |
0.681 |
|
| 2005 |
Dredge BK, Stefani G, Engelhard CC, Darnell RB. Nova autoregulation reveals dual functions in neuronal splicing. The Embo Journal. 24: 1608-20. PMID 15933722 DOI: 10.1038/Sj.Emboj.7600630 |
0.64 |
|
| 2005 |
Darnell JC, Fraser CE, Mostovetsky O, Stefani G, Jones TA, Eddy SR, Darnell RB. Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes. Genes & Development. 19: 903-18. PMID 15805463 DOI: 10.1101/Gad.1276805 |
0.639 |
|
| 2005 |
Relógio A, Ben-Dov C, Baum M, Ruggiu M, Gemund C, Benes V, Darnell RB, Valcárcel J. Alternative splicing microarrays reveal functional expression of neuron-specific regulators in Hodgkin lymphoma cells. The Journal of Biological Chemistry. 280: 4779-84. PMID 15546866 DOI: 10.1074/jbc.M411976200 |
0.34 |
|
| 2004 |
Stefani G, Fraser CE, Darnell JC, Darnell RB. Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells Journal of Neuroscience. 24: 7272-7276. PMID 15317853 DOI: 10.1523/Jneurosci.2306-04.2004 |
0.626 |
|
| 2004 |
Darnell JC, Warren ST, Darnell RB. The Fragile X Mental Retardation Protein, FMRP, Recognizes G-Quartets Mental Retardation and Developmental Disabilities Research Reviews. 10: 49-52. PMID 14994288 DOI: 10.1002/Mrdd.20008 |
0.405 |
|
| 2003 |
Ule J, Jensen KB, Ruggiu M, Mele A, Ule A, Darnell RB. CLIP identifies Nova-regulated RNA networks in the brain. Science (New York, N.Y.). 302: 1212-5. PMID 14615540 DOI: 10.1126/science.1090095 |
0.709 |
|
| 2003 |
Dredge BK, Darnell RB. Nova regulates GABA(A) receptor gamma2 alternative splicing via a distal downstream UCAU-rich intronic splicing enhancer. Molecular and Cellular Biology. 23: 4687-700. PMID 12808107 DOI: 10.1128/MCB.23.13.4687-4700.2003 |
0.336 |
|
| 2003 |
Farina KL, Huttelmaier S, Musunuru K, Darnell R, Singer RH. Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. The Journal of Cell Biology. 160: 77-87. PMID 12507992 DOI: 10.1083/Jcb.200206003 |
0.346 |
|
| 2002 |
Ito M, Okano HJ, Darnell RB, Roeder RG. The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development Embo Journal. 21: 3464-3475. PMID 12093747 DOI: 10.1093/emboj/cdf348 |
0.493 |
|
| 2001 |
O'Donovan KJ, Darnell RB. Neuronal signaling through alternative splicing: some exons CaRRE. Science's Stke : Signal Transduction Knowledge Environment. 2001: pe2. PMID 11752670 DOI: 10.1126/Stke.2001.94.Pe2 |
0.697 |
|
| 2001 |
Darnell JC, Jensen KB, Jin P, Brown V, Warren ST, Darnell RB. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function Cell. 107: 489-499. PMID 11719189 DOI: 10.1016/S0092-8674(01)00566-9 |
0.378 |
|
| 2001 |
Musunuru K, Darnell RB. Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration. Annual Review of Neuroscience. 24: 239-62. PMID 11283311 DOI: 10.1146/ANNUREV.NEURO.24.1.239 |
0.337 |
|
| 2001 |
Dredge BK, Polydorides AD, Darnell RB. The splice of life: alternative splicing and neurological disease. Nature Reviews. Neuroscience. 2: 43-50. PMID 11253358 DOI: 10.1038/35049061 |
0.413 |
|
| 2000 |
Ito M, Yuan CX, Okano HJ, Darnell RB, Roeder RG. Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. Molecular Cell. 5: 683-93. PMID 10882104 DOI: 10.1016/S1097-2765(00)80247-6 |
0.424 |
|
| 2000 |
Polydorides AD, Okano HJ, Yang YY, Stefani G, Darnell RB. A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. Proceedings of the National Academy of Sciences of the United States of America. 97: 6350-5. PMID 10829067 DOI: 10.1073/Pnas.110128397 |
0.674 |
|
| 2000 |
Jensen KB, Musunuru K, Lewis HA, Burley SK, Darnell RB. The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain. Proceedings of the National Academy of Sciences of the United States of America. 97: 5740-5. PMID 10811881 DOI: 10.1073/Pnas.090553997 |
0.359 |
|
| 2000 |
Jensen KB, Dredge BK, Stefani G, Zhong R, Buckanovich RJ, Okano HJ, Yang YY, Darnell RB. Nova-1 regulates neuron-specific alternative splicing and is essential for neuronal viability. Neuron. 25: 359-71. PMID 10719891 DOI: 10.1016/S0896-6273(00)80900-9 |
0.657 |
|
| 2000 |
Lewis HA, Musunuru K, Jensen KB, Edo C, Chen H, Darnell RB, Burley SK. Sequence-specific RNA binding by a Nova KH domain: implications for paraneoplastic disease and the fragile X syndrome. Cell. 100: 323-32. PMID 10676814 DOI: 10.1016/S0092-8674(00)80668-6 |
0.365 |
|
| 1999 |
Akamatsu W, Okano HJ, Osumi N, Inoue T, Nakamura S, Sakakibara S, Miura M, Matsuo N, Darnell RB, Okano H. Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems. Proceedings of the National Academy of Sciences of the United States of America. 96: 9885-90. PMID 10449789 DOI: 10.1073/Pnas.96.17.9885 |
0.408 |
|
| 1999 |
Lewis HA, Chen H, Edo C, Buckanovich RJ, Yang YY, Musunuru K, Zhong R, Darnell RB, Burley SK. Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. Structure (London, England : 1993). 7: 191-203. PMID 10368286 DOI: 10.1016/S0969-2126(99)80025-2 |
0.333 |
|
| 1998 |
Yang YY, Yin GL, Darnell RB. The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 13254-9. PMID 9789075 DOI: 10.1073/pnas.95.22.13254 |
0.415 |
|
| 1997 |
Fei H, Okano HJ, Li C, Lee GH, Zhao C, Darnell R, Friedman JM. Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues. Proceedings of the National Academy of Sciences of the United States of America. 94: 7001-5. PMID 9192681 DOI: 10.1073/Pnas.94.13.7001 |
0.327 |
|
| 1997 |
Buckanovich RJ, Darnell RB. The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo. Molecular and Cellular Biology. 17: 3194-201. PMID 9154818 DOI: 10.1128/MCB.17.6.3194 |
0.436 |
|
| 1997 |
Okano HJ, Darnell RB. A Hierarchy of Hu RNA Binding Proteins in Developing and Adult Neurons The Journal of Neuroscience. 17: 3024-3037. DOI: 10.1523/JNEUROSCI.17-09-03024.1997 |
0.388 |
|
| 1996 |
Darnell RB. Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity, and the brain. Proceedings of the National Academy of Sciences of the United States of America. 93: 4529-36. PMID 8643438 DOI: 10.1073/pnas.93.10.4529 |
0.314 |
|
| 1996 |
Buckanovich R, Yang Y, Darnell R. The onconeural antigen Nova-1 is a neuron-specific RNA-binding protein, the activity of which is inhibited by paraneoplastic antibodies The Journal of Neuroscience. 16: 1114-1122. DOI: 10.1523/JNEUROSCI.16-03-01114.1996 |
0.364 |
|
| 1993 |
Buckanovich RJ, Posner JB, Darnell RB. Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system. Neuron. 11: 657-72. PMID 8398153 DOI: 10.1016/0896-6273(93)90077-5 |
0.382 |
|
| 1991 |
Darnell RB, Furneaux HM, Posner JB. Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 1224-30. PMID 1851215 DOI: 10.1523/Jneurosci.11-05-01224.1991 |
0.319 |
|
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