Tong H. Joh - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Neuroscience Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Kim YS, Joh TH. Matrix metalloproteinases, new insights into the understanding of neurodegenerative disorders. Biomolecules & Therapeutics. 20: 133-43. PMID 24116286 DOI: 10.4062/biomolther.2012.20.2.133  0.92
2012 Choi DH, Cristóvão AC, Guhathakurta S, Lee J, Joh TH, Beal MF, Kim YS. NADPH oxidase 1-mediated oxidative stress leads to dopamine neuron death in Parkinson's disease. Antioxidants & Redox Signaling. 16: 1033-45. PMID 22098189 DOI: 10.1089/ars.2011.3960  0.48
2011 Choi DH, Kim YJ, Kim YG, Joh TH, Beal MF, Kim YS. Role of matrix metalloproteinase 3-mediated alpha-synuclein cleavage in dopaminergic cell death. The Journal of Biological Chemistry. 286: 14168-77. PMID 21330369 DOI: 10.1074/jbc.M111.222430  0.72
2010 Kim EM, Shin EJ, Choi JH, Son HJ, Park IS, Joh TH, Hwang O. Matrix metalloproteinase-3 is increased and participates in neuronal apoptotic signaling downstream of caspase-12 during endoplasmic reticulum stress. The Journal of Biological Chemistry. 285: 16444-52. PMID 20368330 DOI: 10.1074/jbc.M109.093799  0.44
2010 Joh TH, Park HJ, Kim SN, Lee H. Recent development of acupuncture on Parkinson's disease. Neurological Research. 32: 5-9. PMID 20034437 DOI: 10.1179/016164109X12537002793643  0.44
2010 Kim ST, Kim EM, Choi JH, Son HJ, Ji IJ, Joh TH, Chung SJ, Hwang O. Matrix metalloproteinase-3 contributes to vulnerability of the nigral dopaminergic neurons. Neurochemistry International. 56: 161-7. PMID 19815046 DOI: 10.1016/j.neuint.2009.09.014  0.44
2009 Sugama S, Takenouchi T, Cho BP, Joh TH, Hashimoto M, Kitani H. Possible roles of microglial cells for neurotoxicity in clinical neurodegenerative diseases and experimental animal models. Inflammation & Allergy Drug Targets. 8: 277-84. PMID 19754411 DOI: 10.2174/187152809789352249  0.36
2009 Cho Y, Son HJ, Kim EM, Choi JH, Kim ST, Ji IJ, Choi DH, Joh TH, Kim YS, Hwang O. Doxycycline is neuroprotective against nigral dopaminergic degeneration by a dual mechanism involving MMP-3. Neurotoxicity Research. 16: 361-71. PMID 19582534 DOI: 10.1007/s12640-009-9078-1  0.92
2008 Jeon S, Kim YJ, Kim ST, Moon W, Chae Y, Kang M, Chung MY, Lee H, Hong MS, Chung JH, Joh TH, Lee H, Park HJ. Proteomic analysis of the neuroprotective mechanisms of acupuncture treatment in a Parkinson's disease mouse model. Proteomics. 8: 4822-32. PMID 18942673 DOI: 10.1002/pmic.200700955  0.72
2008 Choi DH, Kim EM, Son HJ, Joh TH, Kim YS, Kim D, Flint Beal M, Hwang O. A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells. Journal of Neurochemistry. 106: 405-15. PMID 18397366 DOI: 10.1111/j.1471-4159.2008.05399.x  0.92
2008 Song DY, Yang YC, Shin DH, Sugama S, Kim YS, Lee BH, Joh TH, Cho BP. Axotomy-induced dopaminergic neurodegeneration is accompanied with c-Jun phosphorylation and activation transcription factor 3 expression. Experimental Neurology. 209: 268-78. PMID 18036593 DOI: 10.1016/j.expneurol.2007.09.033  0.92
2007 Park YK, Chung YS, Kim YS, Kwon OY, Joh TH. Inhibition of gene expression and production of iNOS and TNF-alpha in LPS-stimulated microglia by methanol extract of Phellodendri cortex. International Immunopharmacology. 7: 955-62. PMID 17499198 DOI: 10.1016/j.intimp.2006.03.018  0.92
2007 Kim YS, Choi DH, Block ML, Lorenzl S, Yang L, Kim YJ, Sugama S, Cho BP, Hwang O, Browne SE, Kim SY, Hong JS, Beal MF, Joh TH. A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 179-87. PMID 17116747 DOI: 10.1096/fj.06-5865com  0.72
2006 Kim YS, Joh TH. Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease. Experimental & Molecular Medicine. 38: 333-47. PMID 16953112 DOI: 10.1038/emm.2006.40  0.92
2006 Cho BP, Song DY, Sugama S, Shin DH, Shimizu Y, Kim SS, Kim YS, Joh TH. Pathological dynamics of activated microglia following medial forebrain bundle transection. Glia. 53: 92-102. PMID 16206155 DOI: 10.1002/glia.20265  0.92
2005 Kim YS, Kim SS, Cho JJ, Choi DH, Hwang O, Shin DH, Chun HS, Beal MF, Joh TH. Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3701-11. PMID 15814801 DOI: 10.1523/JNEUROSCI.4346-04.2005  0.72
2004 Yang L, Sugama S, Mischak RP, Kiaei M, Bizat N, Brouillet E, Joh TH, Beal MF. A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo. Neurobiology of Disease. 17: 250-9. PMID 15474362 DOI: 10.1016/j.nbd.2004.07.021  0.72
2004 Lee J, Kim YS, Choi DH, Bang MS, Han TR, Joh TH, Kim SY. Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microglia. The Journal of Biological Chemistry. 279: 53725-35. PMID 15471861 DOI: 10.1074/jbc.M407627200  0.92
2004 Park KC, Chung KC, Kim YS, Lee J, Joh TH, Kim SY. Transglutaminase 2 induces nitric oxide synthesis in BV-2 microglia. Biochemical and Biophysical Research Communications. 323: 1055-62. PMID 15381106 DOI: 10.1016/j.bbrc.2004.08.204  0.92
2004 Kim WK, Jang PG, Woo MS, Han IO, Piao HZ, Lee K, Lee H, Joh TH, Kim HS. A new anti-inflammatory agent KL-1037 represses proinflammatory cytokine and inducible nitric oxide synthase (iNOS) gene expression in activated microglia. Neuropharmacology. 47: 243-52. PMID 15223303 DOI: 10.1016/j.neuropharm.2004.03.019  0.72
2003 Yang L, Sugama S, Chirichigno JW, Gregorio J, Lorenzl S, Shin DH, Browne SE, Shimizu Y, Joh TH, Beal MF, Albers DS. Minocycline enhances MPTP toxicity to dopaminergic neurons. Journal of Neuroscience Research. 74: 278-85. PMID 14515357 DOI: 10.1002/jnr.10709  0.72
2003 Cho BP, Sugama S, Shin DH, DeGiorgio LA, Kim SS, Kim YS, Lim SY, Park KC, Volpe BT, Cho S, Joh TH. Microglial phagocytosis of dopamine neurons at early phases of apoptosis. Cellular and Molecular Neurobiology. 23: 551-60. PMID 14514015 DOI: 10.1023/A:1025024129946  0.92
2003 Woo MS, Jang PG, Park JS, Kim WK, Joh TH, Kim HS. Selective modulation of lipopolysaccharide-stimulated cytokine expression and mitogen-activated protein kinase pathways by dibutyryl-cAMP in BV2 microglial cells. Brain Research. Molecular Brain Research. 113: 86-96. PMID 12750010 DOI: 10.1016/S0169-328X(03)00095-0  0.64
2003 Sugama S, Cho BP, Degiorgio LA, Shimizu Y, Kim SS, Kim YS, Shin DH, Volpe BT, Reis DJ, Cho S, Joh TH. Temporal and sequential analysis of microglia in the substantia nigra following medial forebrain bundle axotomy in rat. Neuroscience. 116: 925-33. PMID 12617934 DOI: 10.1016/S0306-4522(02)00572-9  0.72
2003 Sugama S, Yang L, Cho BP, DeGiorgio LA, Lorenzl S, Albers DS, Beal MF, Volpe BT, Joh TH. Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice. Brain Research. 964: 288-94. PMID 12576189 DOI: 10.1016/S0006-8993(02)04085-4  0.72
2002 Sugama S, Cho BP, Baker H, Joh TH, Lucero J, Conti B. Neurons of the superior nucleus of the medial habenula and ependymal cells express IL-18 in rat CNS. Brain Research. 958: 1-9. PMID 12468024 DOI: 10.1016/S0006-8993(02)03363-2  0.36
2002 DeGiorgio LA, Shimizu Y, Chun HS, Kim YS, Sugama S, Son JH, Joh TH, Volpe BT. Amyloid precursor protein gene disruption attenuates degeneration of substantia nigra compacta neurons following axotomy. Brain Research. 938: 38-44. PMID 12031533 DOI: 10.1016/S0006-8993(02)02483-6  0.92
2002 DeGiorgio LA, Shimizu Y, Chun HS, Cho BP, Sugama S, Joh TH, Volpe BT. APP knockout attenuates microglial activation and enhances neuron survival in substantia nigra compacta after axotomy. Glia. 38: 174-8. PMID 11948811 DOI: 10.1002/glia.10052  0.36
2001 Cho S, Kim Y, Cruz MO, Park EM, Chu CK, Song GY, Joh TH. Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: Protein kinase A - Dependent mechanism Glia. 33: 324-333. PMID 11246231 DOI: 10.1002/1098-1136(20010315)33:4<324::AID-GLIA1031>3.0.CO;2-M  0.36
2000 Sugama S, Kim Y, Baker H, Tinti C, Kim H, Joh TH, Conti B. Tissue-specific expression of rat IL-18 gene and response to adrenocorticotropic hormone treatment Journal of Immunology. 165: 6287-6292. PMID 11086064  0.44
1999 Son JH, Chun HS, Joh TH, Cho S, Conti B, Lee JW. Neuroprotection and neuronal differentiation studies using substantia nigra dopaminergic cells derived from transgenic mouse embryos Journal of Neuroscience. 19: 10-20. PMID 9870933  0.4
1998 Jahng JW, Houpt TA, Joh TH, Son JH. Differential expression of monoamine oxidase A, serotonin transporter, tyrosine hydroxylase and norepinephrine transporter mRNA by anorexia mutation and food deprivation. Brain Research. Developmental Brain Research. 107: 241-6. PMID 9593916 DOI: 10.1016/S0165-3806(98)00013-3  0.44
1997 Kirn JS, Chae HD, Joh TH, Kim KT. Stimulation of human DBH gene expression by prostaglandin E2 in human neuroblastoma SK-N-BE(2)C cells Journal of Molecular Neuroscience. 9: 143-150. PMID 9481616  0.4
1997 Kim SJ, Lee JW, Chun HS, Joh TH, Son JH. Monitoring Catecholamine Differentiation in the Embryonic Brain and Peripheral Neurons Using E. coli lacZ as a Reporter Gene Molecules and Cells. 7: 394-398. PMID 9264028  0.48
1997 Son JH, Joh TH. Genetically engineered neural transmission Molecular Psychiatry. 2: 26-31. PMID 9154215  0.96
1997 Suh BC, Son JH, Joh TH, Kim KT. Two distinct P2 purinergic receptors, P2Y and P2U, are coupled to phospholipase C in mouse pineal gland tumor cells. Journal of Neurochemistry. 68: 1622-32. PMID 9084434  0.68
1996 Son JH, Min N, Joh TH. Early ontogeny of catecholaminergic cell lineage in brain and peripheral neurons monitored by tyrosine hydroxylase-lacZ transgene Molecular Brain Research. 36: 300-308. PMID 8965651 DOI: 10.1016/0169-328X(95)00255-Q  0.6
1996 Chae HD, Suh BC, Joh TH, Kim KT. AP1-mediated transcriptional enhancement of the rat tyrosine hydroxylase gene by muscarinic stimulation. Journal of Neurochemistry. 66: 1264-72. PMID 8769893  0.6
1996 Son JH, Chung JH, Huh SO, Park DH, Peng C, Rosenblum MG, Chung YI, Joh TH. Immortalization of neuroendocrine pinealocytes from transgenic mice by targeted tumorigenesis using the tryptophan hydroxylase promoter Molecular Brain Research. 37: 32-40. PMID 8738133 DOI: 10.1016/0169-328X(95)00271-S  0.32
1995 Joh TH, Huh SO, Son JH. Gene expression of serotonergic neurons in the central nervous system: Molecular and developmental analysis Progress in Brain Research. 105: 43-52. PMID 7568896  0.68
1994 Park DH, Stone DM, Baker H, Kim KS, Joh TH. Early induction of rat brain tryptophan hydroxylase (TPH) mRNA following parachlorophenylalanine (PCPA) treatment Molecular Brain Research. 22: 20-28. PMID 8015380 DOI: 10.1016/0169-328X(94)90028-0  0.36
1994 Son JH, Baker H, Park DH, Joh TH. Drastic and selective hyperinnervation of central serotonergic neurons in a lethal neurodevelopmental mouse mutant, Anorexia (anx) Molecular Brain Research. 25: 129-134. PMID 7984037 DOI: 10.1016/0169-328X(94)90287-9  0.52
1994 Huh SO, Park DH, Cho JY, Joh TH, Son JH. A 6.1 kb 5′ upstream region of the mouse tryptophan hydroxylase gene directs expression of E. coli lacZ to major serotonergic brain regions and pineal gland in transgenic mice Molecular Brain Research. 24: 145-152. PMID 7968351 DOI: 10.1016/0169-328X(94)90126-0  0.56
1994 Min N, Joh TH, Kim KS, Peng C, Son JH. 5′ Upstream DNA sequence of the rat tyrosine hydroxylase gene directs high-level and tissue-specific expression to catecholaminergic neurons in the central nervous system of transgenic mice Molecular Brain Research. 27: 281-289. PMID 7898312 DOI: 10.1016/0169-328X(94)90011-6  0.4
1993 Kim KT, Park DH, Joh TH. Parallel up-regulation of catecholamine biosynthetic enzymes by dexamethasone in PC12 cells Journal of Neurochemistry. 60: 946-951. PMID 8436980  0.32
1986 Park JK, Joh TH, Ebner FF. Tyrosine hydroxylase is expressed by neocortical neurons after transplantation. Proceedings of the National Academy of Sciences of the United States of America. 83: 7495-8. PMID 2876427  0.52
1986 Baetge EE, Suh YH, Joh TH. Complete nucleotide and deduced amino acid sequence of bovine phenylethanolamine N-methyltransferase: partial amino acid homology with rat tyrosine hydroxylase. Proceedings of the National Academy of Sciences of the United States of America. 83: 5454-8. PMID 2874553  0.4
1985 Park DH, Joh TH. Species-specific charge forms of phenylethanolamine N-methyltransferase Brain Research. 344: 402-404. PMID 4041886 DOI: 10.1016/0006-8993(85)90824-8  0.32
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