Maria F. Lopes-Virella - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Microbiology Biology, Cell Biology

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hammad SM, Lopes-Virella MF. Circulating Sphingolipids in Insulin Resistance, Diabetes and Associated Complications. International Journal of Molecular Sciences. 24. PMID 37762318 DOI: 10.3390/ijms241814015  0.328
2022 Hammad SM, Hunt KJ, Baker NL, Klein RL, Lopes-Virella MF. Diabetes and kidney dysfunction markedly alter the content of sphingolipids carried by circulating lipoproteins. Journal of Clinical Lipidology. PMID 35148982 DOI: 10.1016/j.jacl.2021.12.004  0.324
2021 Semler A, Hammad S, Lopes-Virella MF, Klein RL, Huang Y. Deoxysphingolipids Upregulate MMP-1, Downregulate TIMP-1, and Induce Cytotoxicity in Human Schwann Cells. Neuromolecular Medicine. PMID 34853975 DOI: 10.1007/s12017-021-08698-4  0.34
2020 Jaffa MA, Bebu I, Luttrell D, Braffett BH, Lachin JM, Hunt K, Lopes-Virella M, Luttrell L, Lyons TJ, Jaffa AA. Longitudinal Plasma Kallikrein Levels and Their Association with the Risk of Cardiovascular Disease Outcomes in Type 1 Diabetes in DCCT/EDIC. Diabetes. PMID 32826295 DOI: 10.2337/Db20-0427  0.332
2020 Braffett BH, Gubitosi-Klug RA, Albers JW, Feldman EL, Martin CL, White NH, Orchard TJ, Lopes-Virella M, Lachin JM, Pop-Busui R. Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Diabetes. PMID 32051148 DOI: 10.2337/Db19-1046  0.384
2020 Bebu I, Schade D, Braffett B, Kosiborod M, Lopes-Virella M, Soliman EZ, Herman WH, Bluemke DA, Wallia A, Orchard T, Lachin JM. Risk Factors for First and Subsequent CVD Events in Type 1 Diabetes: The DCCT/EDIC Study. Diabetes Care. PMID 32001614 DOI: 10.2337/Dc19-2292  0.413
2020 LU Z, LI Y, LOPES-VIRELLA MF, HUANG Y. 1840-P: GPR40 Deficiency Is Associated with Steatosis, Hepatic Inflammation, and CD36 Upregulation in C57BL/6 Mice Diabetes. 69: 1840-P. DOI: 10.2337/Db20-1840-P  0.308
2020 Campos E, Keenan HA, Lopes-Virella MF, Blot WJ, Conway B. 1628-P: Extreme Survival in a Low SES Population with Early-Onset Diabetes Diabetes. 69. DOI: 10.2337/Db20-1628-P  0.332
2019 Lu Z, Li Y, Syn WK, Wang Z, Lopes-Virella MF, Lyons TJ, Huang Y. Amitriptyline Inhibits Nonalcoholic Steatohepatitis and Atherosclerosis Induced by High-Fat Diet and LPS through Modulation of Sphingolipid Metabolism. American Journal of Physiology. Endocrinology and Metabolism. PMID 31821039 DOI: 10.1152/Ajpendo.00181.2019  0.351
2019 Hunt KJ, Jenkins AJ, Fu D, Stevens D, Ma JX, Klein RL, Azar M, Zhang SX, Lopes-Virella MF, Lyons TJ. Serum pigment epithelium-derived factor: Relationships with cardiovascular events, renal dysfunction, and mortality in the Veterans Affairs Diabetes Trial (VADT) cohort. Journal of Diabetes and Its Complications. 107410. PMID 31434620 DOI: 10.1016/J.Jdiacomp.2019.107410  0.371
2019 Lopes-Virella MF, Bebu I, Hunt KJ, Virella G, Baker NL, Braffett B, Gao X, Lachin JM. Immune Complexes and the Risk of CVD in Type 1 Diabetes. Diabetes. PMID 31217176 DOI: 10.2337/Db19-0358  0.453
2019 Basu A, Bebu I, Jenkins AJ, Stoner JA, Zhang Y, Klein RL, Lopes-Virella MF, Garvey WT, Budoff MJ, Alaupovic P, Lyons TJ. Serum apolipoproteins and apolipoprotein-defined lipoprotein subclasses: a hypothesis-generating prospective study of cardiovascular events in type 1 diabetes. Journal of Lipid Research. PMID 31203233 DOI: 10.1194/Jlr.P090647  0.404
2019 Lopes-Virella MF, Baker NL, Hunt KJ, Hammad SM, Arthur J, Virella G, Klein RL. Glycosylated sphingolipids and progression to kidney dysfunction in type 1 diabetes. Journal of Clinical Lipidology. PMID 31043336 DOI: 10.1016/J.Jacl.2019.03.005  0.375
2019 Kelly CB, Hammad SM, Klein RL, Lopes-Virella MF, Gosmanova A, Leyva MJ, Aston CE, Lyons T. 609-P: Effect of Rosuvastatin on Lipoprotein Sphingolipids in Patients with Type 2 Diabetes Diabetes. 68. DOI: 10.2337/Db19-609-P  0.408
2019 Lopes-Virella MF, Bebu I, Hunt KJ, Virella G, Baker NL, Braffett B, Lachin J, Dcct. 445-P: Modified LDL-Immune Complexes (IC) and the Risk of CVD in Type 1 Diabetes Diabetes. 68. DOI: 10.2337/Db19-445-P  0.431
2019 Braffett B, Gubitosi-Klug R, Albers JW, Feldman EL, Martin C, White NH, Orchard TJ, Lopes-Virella MF, Raskin P, Pop-Busui R. 322-OR: Risk Factors for Peripheral and Cardiovascular Autonomic Neuropathy in Type 1 Diabetes: Thirty Years of Follow-Up in DCCT/EDIC Diabetes. 68. DOI: 10.2337/Db19-322-Or  0.378
2019 Karanchi H, Kelly CB, Hammad SM, Klein RL, Lopes-Virella MF, Leyva MJ, Yu J, Jenkins AJ, Nankervis AJ, Hanssen KF, Aston CE, Howell S, Beisswenger PJ, Lyons T. 198-LB: Maternal Plasma AGEs and Preeclampsia in Women with Type 1 Diabetes Diabetes. 68. DOI: 10.2337/Db19-198-Lb  0.343
2019 LU Z, LI Y, LOPES-VIRELLA MF, HUANG Y. 1889-P: Inhibition of Acid Sphingomyelinase Attenuates Nonalcoholic Steatohepatitis and Atherosclerosis Induced by High-Fat Diet and LPS in LDL Receptor-Deficient Mice Diabetes. 68: 1889-P. DOI: 10.2337/Db19-1889-P  0.342
2019 Kelly CB, Hammad SM, Klein RL, Lopes-Virella MF, Leyva MJ, Yu J, Jenkins AJ, Nankervis AJ, Hanssen KF, Garg SK, Scardo JA, Aston CE, Lyons T. 1391-P: Longitudinal Changes of Plasma Sphingomyelins during Gestation in Women With and Without Type 1 Diabetes and Preeclampsia Diabetes. 68. DOI: 10.2337/Db19-1391-P  0.371
2019 Kelly CB, Hammad SM, Klein RL, Lopes-Virella MF, Leyva MJ, Yu J, Jenkins AJ, Nankervis AJ, Hanssen KF, Garg SK, Scardo JA, Aston CE, Lyons T. 1390-P: Maternal Plasma Ceramides Predict Preeclampsia in Women with Type 1 Diabetes Diabetes. 68. DOI: 10.2337/Db19-1390-P  0.335
2018 Lu Z, Li Y, Ru JH, Lopes-Virella MF, Lyons TJ, Huang Y. Interaction of palmitate and LPS regulates cytokine expression and apoptosis through sphingolipids in human retinal microvascular endothelial cells. Experimental Eye Research. PMID 30273577 DOI: 10.1016/J.Exer.2018.09.016  0.342
2018 Li Y, Lu Z, Ru JH, Lopes-Virella MF, Lyons TJ, Huang Y. Saturated Fatty Acid Combined with Lipopolysaccharide Stimulates a Strong Inflammatory Response in Hepatocytes in vivo and in vitro. American Journal of Physiology. Endocrinology and Metabolism. PMID 29989851 DOI: 10.1152/Ajpendo.00015.2018  0.319
2018 Lopes-Virella MF, Virella G. Modified LDL immune complexes and cardiovascular disease. Current Medicinal Chemistry. PMID 29792135 DOI: 10.2174/0929867325666180524114429  0.42
2018 Basu A, Jenkins AJ, Stoner JA, Zhang Y, Klein RL, Lopes-Virella MF, Garvey WT, Schade DS, Wood J, Alaupovic P, Lyons TJ. Apolipoprotein-defined Lipoprotein Subclasses, Serum Apolipoproteins and Carotid Intima-Media Thickness in Type 1 Diabetes. Journal of Lipid Research. PMID 29576550 DOI: 10.1194/Jlr.P080143  0.419
2018 Hunt KJ, Jaffa MA, Garrett SM, Luttrell DK, Lipson KE, Lopes-Virella MF, Luttrell LM, Jaffa AA. Plasma Connective Tissue Growth Factor (CTGF/CCN2) Levels Predict Myocardial Infarction in the Veterans Affairs Diabetes Trial (VADT) Cohort. Diabetes Care. PMID 29382658 DOI: 10.2337/Dc17-2083  0.399
2018 Basu A, Braffett B, Jenkins A, Bebu I, Klein RL, Lopes-Virella MF, Dagogo-Jack S, Orchard TJ, Wallia A, Lachin J, Garvey WT, Lyons T, Dcct. Uric Acid and Cardiovascular Disease in Type 1 Diabetes Diabetes. 67. DOI: 10.2337/Db18-189-Lb  0.354
2018 Basu A, Bebu I, Jenkins A, Stoner J, Zhang Y, Klein RL, Lopes-Virella MF, Garvey WT, Budoff M, Lyons T, Dcct. Serum Apolipoprotein C-III and Cardiovascular Events in Type 1 Diabetes Diabetes. 67. DOI: 10.2337/Db18-188-Lb  0.405
2017 Baker NL, Hunt KJ, Stevens DR, Jarai G, Rosen GD, Klein RL, Virella G, Lopes-Virella MF. Association Between Inflammatory Markers and Progression to Kidney Dysfunction: Examining Different Assessment Windows in Patients With Type 1 Diabetes. Diabetes Care. PMID 29118060 DOI: 10.2337/Dc17-0867  0.377
2017 Lu Z, Li Y, Brinson CW, Lopes-Virella MF, Huang Y. Cooperative stimulation of atherogenesis by lipopolysaccharide and palmitic acid-rich high fat diet in low-density lipoprotein receptor-deficient mice. Atherosclerosis. 265: 231-241. PMID 28934649 DOI: 10.1016/J.Atherosclerosis.2017.09.008  0.328
2017 Virella G, Wilson K, Elkes J, Hammad SM, Rajab HA, Li Y, Chassereau C, Huang Y, Lopes-Virella M. Immune complexes containing malondialdehyde (MDA) LDL induce apoptosis in human macrophages. Clinical Immunology (Orlando, Fla.). PMID 28689783 DOI: 10.1016/J.Clim.2017.06.010  0.392
2016 Lee MH, Appleton KM, El-Shewy HM, Sorci-Thomas MG, Thomas MJ, Lopes-Virella MF, Luttrell LM, Hammad SM, Klein RL. S1P in HDL Promotes Interaction Between SR-BI and S1PR1 and Activates S1PR1-Mediated Biological Functions: Calcium Flux and S1PR1 Internalization. Journal of Lipid Research. PMID 27881715 DOI: 10.1194/Jlr.M070706  0.317
2016 Orchard TJ, Backlund JC, Costacou T, Cleary P, Lopes-Virella M, Levy AP, Lachin JM. Haptoglobin 2-2 genotype and the risk of coronary artery disease in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC). Journal of Diabetes and Its Complications. PMID 27539884 DOI: 10.1016/J.Jdiacomp.2016.07.014  0.408
2016 Li Y, Lu Z, Huang Y, Lopes-Virella MF, Virella G. F(ab')2 fragments of anti-oxidized LDL IgG attenuate vascular inflammation and atherogenesis in diabetic LDL receptor-deficient mice. Clinical Immunology (Orlando, Fla.). PMID 27455858 DOI: 10.1016/J.Clim.2016.07.020  0.432
2016 Hammad SM, Baker NL, El Abiad JM, Spassieva SD, Pierce JS, Rembiesa B, Bielawski J, Lopes-Virella MF, Klein RL. Increased Plasma Levels of Select Deoxy-ceramide and Ceramide Species are Associated with Increased Odds of Diabetic Neuropathy in Type 1 Diabetes: A Pilot Study. Neuromolecular Medicine. PMID 27388466 DOI: 10.1007/S12017-016-8423-9  0.408
2016 Lopes-Virella MF, Hunt KJ, Baker NL, Virella G. High levels of AGE-LDL, and of IgG antibodies reacting with MDA-lysine epitopes expressed by oxLDL and MDA-LDL in circulating immune complexes predict macroalbuminuria in patients with type 2 diabetes. Journal of Diabetes and Its Complications. 30: 693-9. PMID 26861948 DOI: 10.1016/J.Jdiacomp.2016.01.012  0.484
2016 Basu A, Jenkins AJ, Zhang Y, Stoner JA, Klein RL, Lopes-Virella MF, Timothy Garvey W, Lyons TJ. Data on carotid intima-media thickness and lipoprotein subclasses in type 1 diabetes from the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC). Data in Brief. 6: 33-8. PMID 26759826 DOI: 10.1016/J.Dib.2015.11.036  0.462
2016 Basu A, Jenkins AJ, Zhang Y, Stoner JA, Klein RL, Lopes-Virella MF, Timothy Garvey W, Lyons TJ, The DCCT/EDIC Research Group. Data on carotid intima-media thickness and lipoprotein subclasses in type 1 diabetes from the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Data in Brief. 6: 33-38. DOI: 10.1016/j.dib.2015.11.036  0.307
2015 Zhang Y, Jenkins AJ, Basu A, Stoner JA, Lopes-Virella MF, Klein RL, Cleary PA, Lyons TJ. Associations between intensive diabetes therapy and NMR-determined lipoprotein subclass profiles in Type 1 diabetes. Journal of Lipid Research. PMID 26658239 DOI: 10.1194/Jlr.P060657  0.439
2015 Jaffa MA, Luttrell D, Schmaier AH, Klein RL, Lopes-Virella M, Luttrell LM, Jaffa AA. Plasma Prekallikrein is Associated with Carotid Intima-Media Thickness in Type 1 Diabetes. Diabetes. PMID 26603531 DOI: 10.2337/Db15-0930  0.429
2015 Basu A, Jenkins AJ, Zhang Y, Stoner JA, Klein RL, Lopes-Virella MF, Garvey WT, Lyons TJ. Nuclear magnetic resonance-determined lipoprotein subclasses and carotid intima-media thickness in type 1 diabetes. Atherosclerosis. 244: 93-100. PMID 26600440 DOI: 10.1016/J.Atherosclerosis.2015.10.106  0.395
2015 Lu Z, Zhang X, Li Y, Lopes-Virella MF, Huang Y. TLR4 antagonist attenuates atherogenesis in LDL receptor-deficient mice with diet-induced type 2 diabetes. Immunobiology. PMID 26162692 DOI: 10.1016/J.Imbio.2015.06.016  0.422
2015 Hunt KJ, Baker NL, Cleary PA, Klein R, Virella G, Lopes-Virella MF. Longitudinal Association Between Endothelial Dysfunction, Inflammation, and Clotting Biomarkers With Subclinical Atherosclerosis in Type 1 Diabetes: An Evaluation of the DCCT/EDIC Cohort. Diabetes Care. 38: 1281-9. PMID 25852210 DOI: 10.2337/Dc14-2877  0.387
2015 Li Y, Lu Z, Zhang X, Yu H, Kirkwood KL, Lopes-Virella MF, Huang Y. Metabolic syndrome exacerbates inflammation and bone loss in periodontitis. Journal of Dental Research. 94: 362-70. PMID 25503900 DOI: 10.1177/0022034514561658  0.309
2015 Rajab HA, Baker NL, Hunt KJ, Klein R, Cleary PA, Lachin J, Virella G, Lopes-Virella MF. The predictive role of markers of Inflammation and endothelial dysfunction on the course of diabetic retinopathy in type 1 diabetes. Journal of Diabetes and Its Complications. 29: 108-14. PMID 25441222 DOI: 10.1016/J.Jdiacomp.2014.08.004  0.425
2014 Virella G, Lopes-Virella MF. The role of the immune system in the pathogenesis of diabetic complications. Frontiers in Endocrinology. 5: 126. PMID 25126086 DOI: 10.3389/Fendo.2014.00126  0.44
2014 Klein RL, Hammad SM, Baker NL, Hunt KJ, Al Gadban MM, Cleary PA, Virella G, Lopes-Virella MF. Decreased plasma levels of select very long chain ceramide species are associated with the development of nephropathy in type 1 diabetes. Metabolism: Clinical and Experimental. 63: 1287-95. PMID 25088746 DOI: 10.1016/J.Metabol.2014.07.001  0.414
2014 Basu A, Jenkins AJ, Stoner JA, Thorpe SR, Klein RL, Lopes-Virella MF, Garvey WT, Lyons TJ. Plasma total homocysteine and carotid intima-media thickness in type 1 diabetes: a prospective study. Atherosclerosis. 236: 188-95. PMID 25063949 DOI: 10.1016/J.Atherosclerosis.2014.07.001  0.41
2014 Fu D, Yu JY, Wu M, Du M, Chen Y, Abdelsamie SA, Li Y, Chen J, Boulton ME, Ma JX, Lopes-Virella MF, Virella G, Lyons TJ. Immune complex formation in human diabetic retina enhances toxicity of oxidized LDL towards retinal capillary pericytes. Journal of Lipid Research. 55: 860-9. PMID 24616481 DOI: 10.1194/Jlr.M045401  0.468
2014 Jenkins AJ, Fu D, Azar M, Stoner JA, Kaufman DG, Zhang S, Klein RL, Lopes-Virella MF, Ma JX, Lyons TJ. Clinical correlates of serum pigment epithelium-derived factor in type 2 diabetes patients. Journal of Diabetes and Its Complications. 28: 353-9. PMID 24560422 DOI: 10.1016/J.Jdiacomp.2014.01.008  0.399
2014 Lopes-Virella MF, Baker NL, Hunt KJ, Cleary PA, Klein R, Virella G. Response to comment on Lopes-Virella et al. Baseline markers of inflammation are associated with progression to macroalbuminuria in type 1 diabetic subjects. Diabetes care 2013;36:2317-2323. Diabetes Care. 37: e108-9. PMID 24496801 DOI: 10.2337/Dc13-2976  0.44
2014 Jin J, Zhang X, Lu Z, Li Y, Lopes-Virella MF, Yu H, Haycraft CJ, Li Q, Kirkwood KL, Huang Y. Simvastatin inhibits lipopolysaccharide-induced osteoclastogenesis and reduces alveolar bone loss in experimental periodontal disease Journal of Periodontal Research. 49: 518-526. PMID 24117880 DOI: 10.1111/Jre.12132  0.306
2013 Hunt KJ, Baker N, Cleary P, Backlund JY, Lyons T, Jenkins A, Virella G, Lopes-Virella MF. Oxidized LDL and AGE-LDL in circulating immune complexes strongly predict progression of carotid artery IMT in type 1 diabetes. Atherosclerosis. 231: 315-22. PMID 24267245 DOI: 10.1016/J.Atherosclerosis.2013.09.027  0.439
2013 Lopes-Virella MF, Virella G. Pathogenic role of modified LDL antibodies and immune complexes in atherosclerosis. Journal of Atherosclerosis and Thrombosis. 20: 743-54. PMID 23965492 DOI: 10.5551/Jat.19281  0.429
2013 Azar M, Lyons TJ, Alaupovic P, Stoner JA, Quiroga C, Kaufman DG, Lopes-Virella M, Klein RL, Jenkins AJ. Apolipoprotein-defined and NMR lipoprotein subclasses in the veterans affairs diabetes trial. Journal of Diabetes and Its Complications. 27: 627-32. PMID 23911536 DOI: 10.1016/J.Jdiacomp.2013.05.005  0.384
2013 Jenkins AJ, Yu J, Alaupovic P, Basu A, Klein RL, Lopes-Virella M, Baker NL, Hunt KJ, Lackland DT, Garvey WT, Lyons TJ. Apolipoprotein-defined lipoproteins and apolipoproteins: associations with abnormal albuminuria in type 1 diabetes in the diabetes control and complications trial/epidemiology of diabetes interventions and complications cohort. Journal of Diabetes and Its Complications. 27: 447-53. PMID 23850262 DOI: 10.1016/J.Jdiacomp.2013.06.002  0.436
2013 Lu Z, Li Y, Samuvel DJ, Jin J, Zhang X, Lopes-Virella MF, Huang Y. MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-γ and high glucose in mononuclear cells - a potential role of MD-2 in Toll-like receptor 4-independent signalling. Immunology. 140: 301-13. PMID 23800176 DOI: 10.1111/Imm.12138  0.332
2013 Bhensdadia NM, Hunt KJ, Lopes-Virella MF, Michael Tucker J, Mataria MR, Alge JL, Neely BA, Janech MG, Arthur JM. Urine haptoglobin levels predict early renal functional decline in patients with type 2 diabetes. Kidney International. 83: 1136-43. PMID 23536133 DOI: 10.1038/Ki.2013.57  0.376
2013 Lopes-Virella MF, Baker NL, Hunt KJ, Cleary PA, Klein R, Virella G. Baseline markers of inflammation are associated with progression to macroalbuminuria in type 1 diabetic subjects. Diabetes Care. 36: 2317-23. PMID 23514730 DOI: 10.2337/Dc12-2521  0.443
2013 Virella G, Colglazier J, Chassereau C, Hunt KJ, Baker NL, Lopes-Virella MF. Immunoassay of modified forms of human low density lipoprotein in isolated circulating immune complexes. Journal of Immunoassay & Immunochemistry. 34: 61-74. PMID 23323982 DOI: 10.1080/15321819.2012.683500  0.464
2013 Lopes-Virella MF, Virella G. The role of immunity and inflammation in the development of diabetic complications Diabetology International. 4: 1-8. DOI: 10.1007/S13340-013-0105-3  0.484
2012 Lopes-Virella MF, Hunt KJ, Baker NL, Virella G, Moritz T. The levels of MDA-LDL in circulating immune complexes predict myocardial infarction in the VADT study. Atherosclerosis. 224: 526-31. PMID 22963984 DOI: 10.1016/J.Atherosclerosis.2012.08.006  0.492
2012 Virella G, Lopes-Virella MF. The Pathogenic Role of the Adaptive Immune Response to Modified LDL in Diabetes. Frontiers in Endocrinology. 3: 76. PMID 22715334 DOI: 10.3389/Fendo.2012.00076  0.504
2012 Lu Z, Li Y, Jin J, Zhang X, Lopes-Virella MF, Huang Y. Toll-like receptor 4 activation in microvascular endothelial cells triggers a robust inflammatory response and cross talk with mononuclear cells via interleukin-6. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1696-706. PMID 22596222 DOI: 10.1161/Atvbaha.112.251181  0.34
2012 Lopes-Virella MF, Baker NL, Hunt KJ, Lyons TJ, Jenkins AJ, Virella G. High concentrations of AGE-LDL and oxidized LDL in circulating immune complexes are associated with progression of retinopathy in type 1 diabetes. Diabetes Care. 35: 1333-40. PMID 22511260 DOI: 10.2337/Dc11-2040  0.464
2012 Truman JP, Al Gadban MM, Smith KJ, Jenkins RW, Mayroo N, Virella G, Lopes-Virella MF, Bielawska A, Hannun YA, Hammad SM. Differential regulation of acid sphingomyelinase in macrophages stimulated with oxidized low-density lipoprotein (LDL) and oxidized LDL immune complexes: role in phagocytosis and cytokine release. Immunology. 136: 30-45. PMID 22236141 DOI: 10.1111/J.1365-2567.2012.03552.X  0.387
2012 Lopes-Virella MF, Carter RE, Baker NL, Lachin J, Virella G. High levels of oxidized LDL in circulating immune complexes are associated with increased odds of developing abnormal albuminuria in Type 1 diabetes. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 27: 1416-23. PMID 21856760 DOI: 10.1093/Ndt/Gfr454  0.455
2012 Lopes-Virella MF, Virella G, Hunt KJ, Baker NL, Moritz T. Levels of MDA-LDL in Circulating Immune Complexes Predict Myocardial Infarction in the Veterans Affairs Diabetes Trial (VADT) Cohort Journal of Clinical Lipidology. 6: 256. DOI: 10.1016/J.Jacl.2012.04.014  0.414
2011 Jin J, Samuvel DJ, Zhang X, Li Y, Lu Z, Lopes-Virella MF, Huang Y. Coactivation of TLR4 and TLR2/6 coordinates an additive augmentation on IL-6 gene transcription via p38MAPK pathway in U937 mononuclear cells. Molecular Immunology. 49: 423-32. PMID 22030478 DOI: 10.1016/J.Molimm.2011.08.026  0.319
2011 Samuvel DJ, Jin J, Sundararaj KP, Li Y, Zhang X, Lopes-Virella MF, Huang Y. TLR4 activation and IL-6-mediated cross talk between adipocytes and mononuclear cells synergistically stimulate MMP-1 expression. Endocrinology. 152: 4662-71. PMID 21952248 DOI: 10.1210/En.2011-1026  0.306
2011 Ta NN, Schuyler CA, Li Y, Lopes-Virella MF, Huang Y. DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice. Journal of Cardiovascular Pharmacology. 58: 157-66. PMID 21558879 DOI: 10.1097/Fjc.0B013E31821E5626  0.375
2011 Schuyler CA, Ta NN, Li Y, Lopes-Virella MF, Huang Y. Insulin treatment attenuates diabetes-increased atherosclerotic intimal lesions and matrix metalloproteinase 9 expression in apolipoprotein E-deficient mice. The Journal of Endocrinology. 210: 37-46. PMID 21478228 DOI: 10.1530/Joe-10-0420  0.415
2011 Abdelsamie SA, Li Y, Huang Y, Lee MH, Klein RL, Virella G, Lopes-Virella MF. Oxidized LDL immune complexes stimulate collagen IV production in mesangial cells via Fc gamma receptors I and III. Clinical Immunology (Orlando, Fla.). 139: 258-66. PMID 21439910 DOI: 10.1016/J.Clim.2011.01.016  0.378
2011 Brown WV, Goldberg RB, Lopes-Virella M, Reaven P. Reducing vascular disease risk in the type 2 diabetic patient. Journal of Clinical Lipidology. 5: 3-11. PMID 21262501 DOI: 10.1016/J.Jacl.2010.11.005  0.325
2011 Lopes-Virella MF, Baker NL, Hunt KJ, Lachin J, Nathan D, Virella G. Oxidized LDL immune complexes and coronary artery calcification in type 1 diabetes. Atherosclerosis. 214: 462-7. PMID 21156319 DOI: 10.1016/J.Atherosclerosis.2010.11.012  0.423
2011 Lopes-Virella MF, Hunt KJ, Baker NL, Lachin J, Nathan DM, Virella G. Levels of oxidized LDL and advanced glycation end products-modified LDL in circulating immune complexes are strongly associated with increased levels of carotid intima-media thickness and its progression in type 1 diabetes. Diabetes. 60: 582-9. PMID 20980456 DOI: 10.2337/Db10-0915  0.483
2011 Klein RL, Carter RE, Jenkins AJ, Lyons TJ, Baker NL, Gilbert GE, Virella G, Lopes-Virella MF. LDL-containing immune complexes in the DCCT/EDIC cohort: associations with lipoprotein subclasses. Journal of Diabetes and Its Complications. 25: 73-82. PMID 20605479 DOI: 10.1016/J.Jdiacomp.2010.03.001  0.387
2010 Ta NN, Li Y, Schuyler CA, Lopes-Virella MF, Huang Y. DPP-4 (CD26) inhibitor alogliptin inhibits TLR4-mediated ERK activation and ERK-dependent MMP-1 expression by U937 histiocytes. Atherosclerosis. 213: 429-35. PMID 20843518 DOI: 10.1016/J.Atherosclerosis.2010.08.064  0.301
2010 Al Gadban MM, Smith KJ, Soodavar F, Piansay C, Chassereau C, Twal WO, Klein RL, Virella G, Lopes-Virella MF, Hammad SM. Differential trafficking of oxidized LDL and oxidized LDL immune complexes in macrophages: impact on oxidative stress. Plos One. 5. PMID 20824093 DOI: 10.1371/Journal.Pone.0012534  0.375
2010 Lee MH, Hammad SM, Semler AJ, Luttrell LM, Lopes-Virella MF, Klein RL. HDL3, but not HDL2, stimulates plasminogen activator inhibitor-1 release from adipocytes: the role of sphingosine-1-phosphate. Journal of Lipid Research. 51: 2619-28. PMID 20522601 DOI: 10.1194/Jlr.M003988  0.313
2010 Wang B, Carter RE, Jaffa MA, Nakerakanti S, Lackland D, Lopes-Virella M, Trojanowska M, Luttrell LM, Jaffa AA. Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes. Journal of Medical Genetics. 47: 391-7. PMID 20522428 DOI: 10.1136/Jmg.2009.073098  0.372
2010 Smith KJ, Twal WO, Soodavar F, Virella G, Lopes-Virella MF, Hammad SM. Heat shock protein 70B' (HSP70B') expression and release in response to human oxidized low density lipoprotein immune complexes in macrophages. The Journal of Biological Chemistry. 285: 15985-93. PMID 20348092 DOI: 10.1074/Jbc.M110.113605  0.382
2010 Samuvel DJ, Sundararaj KP, Li Y, Lopes-Virella MF, Huang Y. Adipocyte-mononuclear cell interaction, Toll-like receptor 4 activation, and high glucose synergistically up-regulate osteopontin expression via an interleukin 6-mediated mechanism. The Journal of Biological Chemistry. 285: 3916-27. PMID 20007708 DOI: 10.1074/Jbc.M109.033951  0.314
2010 Lopes-Virella MF, Virella G. Clinical significance of the humoral immune response to modified LDL. Clinical Immunology (Orlando, Fla.). 134: 55-65. PMID 19427818 DOI: 10.1016/J.Clim.2009.04.001  0.452
2010 Wang B, Carter RE, Jaffa MA, Nakerakanti S, Lackland D, Lopes-Virella M, Trojanowska M, Luttrell LM, Jaffa AA. Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes (Journal of Medical Genetics (2010) 47, (391e7) DOI:10.1136/jmg.2009.073098) Journal of Medical Genetics. 47: 768. DOI: 10.1136/Jmg.2009.073098Corr1  0.304
2009 Fernandes JK, Wiegand RE, Salinas CF, Grossi SG, Sanders JJ, Lopes-Virella MF, Slate EH. Periodontal disease status in gullah african americans with type 2 diabetes living in South Carolina. Journal of Periodontology. 80: 1062-8. PMID 19563285 DOI: 10.1902/Jop.2009.080486  0.374
2009 Sundararaj KP, Samuvel DJ, Li Y, Sanders JJ, Lopes-Virella MF, Huang Y. Interleukin-6 released from fibroblasts is essential for up-regulation of matrix metalloproteinase-1 expression by U937 macrophages in coculture: cross-talking between fibroblasts and U937 macrophages exposed to high glucose. The Journal of Biological Chemistry. 284: 13714-24. PMID 19307187 DOI: 10.1074/Jbc.M806573200  0.33
2009 Samuvel DJ, Sundararaj KP, Nareika A, Lopes-Virella MF, Huang Y. Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation. Journal of Immunology (Baltimore, Md. : 1950). 182: 2476-84. PMID 19201903 DOI: 10.4049/Jimmunol.0802059  0.302
2009 Hammad SM, Twal WO, Barth JL, Smith KJ, Saad AF, Virella G, Argraves WS, Lopes-Virella MF. Oxidized LDL immune complexes and oxidized LDL differentially affect the expression of genes involved with inflammation and survival in human U937 monocytic cells. Atherosclerosis. 202: 394-404. PMID 18597759 DOI: 10.1016/J.Atherosclerosis.2008.05.032  0.351
2009 Nareika A, Sundararaj KP, Im YB, Game BA, Lopes-Virella MF, Huang Y. High glucose and interferon gamma synergistically stimulate MMP-1 expression in U937 macrophages by increasing transcription factor STAT1 activity. Atherosclerosis. 202: 363-71. PMID 18586252 DOI: 10.1016/J.Atherosclerosis.2008.05.043  0.39
2009 Wu M, Chen Y, Abdel-samie SA, Wilson K, Boulton ME, Ma JX, Virella G, Lopes-Virella MF, Lyons TJ. Role of ox-LDL immunocomplexes in diabetic retinopathy Canadian Journal of Diabetes. 33: 222-223. DOI: 10.1016/S1499-2671(09)33102-0  0.446
2008 Brown WV, Clark L, Falko JM, Guyton JR, Rees TJ, Schonfeld G, Lopes-Virella MF. Optimal management of lipids in diabetes and metabolic syndrome. Journal of Clinical Lipidology. 2: 335-42. PMID 21291758 DOI: 10.1016/J.Jacl.2008.08.444  0.436
2008 White NH, Sun W, Cleary PA, Danis RP, Davis MD, Hainsworth DP, Hubbard LD, Lachin JM, Nathan DM, Crofford O, Crandall J, Phillips M, Reid M, Brown-Friday J, Engel S, ... ... Lopes-Virella M, et al. Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the diabetes control and complications trial Archives of Ophthalmology. 126: 1707-1715. PMID 19064853 DOI: 10.1001/Archopht.126.12.1707  0.401
2008 Lopes-Virella MF, Carter RE, Gilbert GE, Klein RL, Jaffa M, Jenkins AJ, Lyons TJ, Garvey WT, Virella G. Risk factors related to inflammation and endothelial dysfunction in the DCCT/EDIC cohort and their relationship with nephropathy and macrovascular complications. Diabetes Care. 31: 2006-12. PMID 18628568 DOI: 10.2337/Dc08-0659  0.411
2008 Cole CM, Sundararaj KP, Leite RS, Nareika A, Slate EH, Sanders JJ, Lopes-Virella MF, Huang Y. A trend of increase in periodontal interleukin-6 expression across patients with neither diabetes nor periodontal disease, patients with periodontal disease alone, and patients with both diseases Journal of Periodontal Research. 43: 717-722. PMID 18627438 DOI: 10.1111/J.1600-0765.2008.01082.X  0.36
2008 Sundararaj KP, Samuvel DJ, Li Y, Nareika A, Slate EH, Sanders JJ, Lopes-Virella MF, Huang Y. Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation. Journal of Leukocyte Biology. 84: 1120-9. PMID 18625914 DOI: 10.1189/Jlb.0108064  0.303
2008 Virella G, Carter RE, Saad A, Crosswell EG, Game BA, Lopes-Virella MF. Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy. Clinical Immunology (Orlando, Fla.). 127: 394-400. PMID 18533284 DOI: 10.1016/J.Clim.2008.02.005  0.385
2008 Virella G, Lopes-Virella MF. Atherogenesis and the humoral immune response to modified lipoproteins. Atherosclerosis. 200: 239-46. PMID 18513726 DOI: 10.1016/J.Atherosclerosis.2008.03.025  0.383
2008 Jaffa AA, Usinger WR, McHenry MB, Jaffa MA, Lipstiz SR, Lackland D, Lopes-Virella M, Luttrell LM, Wilson PW. Connective tissue growth factor and susceptibility to renal and vascular disease risk in type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism. 93: 1893-900. PMID 18319310 DOI: 10.1210/Jc.2007-2544  0.358
2008 Brock JW, Jenkins AJ, Lyons TJ, Klein RL, Yim E, Lopes-Virella M, Carter RE, Thorpe SR, Baynes JW. Increased methionine sulfoxide content of apoA-I in type 1 diabetes. Journal of Lipid Research. 49: 847-55. PMID 18202432 DOI: 10.1194/Jlr.M800015-Jlr200  0.443
2008 Colwell JA, Lyons TJ, Klein RL, Lopes-Virella MF, Jokl RJ. Atherosclerosis and Thrombosis in Diabetes Mellitus: New Aspects of Pathogenesis Levin and O'Neal's: the Diabetic Foot. 89-113. DOI: 10.1016/B978-0-323-04145-4.50012-0  0.309
2007 Carter RE, Lackland DT, Cleary PA, Yim E, Lopes-Virella MF, Gilbert GE, Orchard TJ. Intensive treatment of diabetes is associated with a reduced rate of peripheral arterial calcification in the diabetes control and complications trial. Diabetes Care. 30: 2646-8. PMID 17623823 DOI: 10.2337/Dc07-0517  0.423
2007 Nareika A, Maldonado A, He L, Game BA, Slate EH, Sanders JJ, London SD, Lopes-Virella MF, Huang Y. High glucose-boosted inflammatory responses to lipopolysaccharide are suppressed by statin. Journal of Periodontal Research. 42: 31-8. PMID 17214637 DOI: 10.1111/J.1600-0765.2006.00911.X  0.428
2007 Game BA, He L, Jarido V, Nareika A, Jaffa AA, Lopes-Virella MF, Huang Y. Pioglitazone inhibits connective tissue growth factor expression in advanced atherosclerotic plaques in low-density lipoprotein receptor-deficient mice. Atherosclerosis. 192: 85-91. PMID 16901490 DOI: 10.1016/J.Atherosclerosis.2006.06.025  0.349
2007 Lopes-Virella MF, McHenry MB, Lipsitz S, Yim E, Wilson PF, Lackland DT, Lyons T, Jenkins AJ, Virella G. Immune complexes containing modified lipoproteins are related to the progression of internal carotid intima-media thickness in patients with type 1 diabetes. Atherosclerosis. 190: 359-69. PMID 16530770 DOI: 10.1016/J.Atherosclerosis.2006.02.007  0.502
2006 Lyons TJ, Jenkins AJ, Zheng D, Klein RL, Otvos JD, Yu Y, Lackland DT, McGee D, McHenry MB, Lopes-Virella M, Garvey WT. Nuclear magnetic resonance-determined lipoprotein subclass profile in the DCCT/EDIC cohort: associations with carotid intima-media thickness. Diabetic Medicine : a Journal of the British Diabetic Association. 23: 955-66. PMID 16922701 DOI: 10.1111/J.1464-5491.2006.01905.X  0.335
2006 Saad AF, Virella G, Chassereau C, Boackle RJ, Lopes-Virella MF. OxLDL immune complexes activate complement and induce cytokine production by MonoMac 6 cells and human macrophages. Journal of Lipid Research. 47: 1975-83. PMID 16804192 DOI: 10.1194/Jlr.M600064-Jlr200  0.376
2006 Hammad SM, Taha TA, Nareika A, Johnson KR, Lopes-Virella MF, Obeid LM. Oxidized LDL immune complexes induce release of sphingosine kinase in human U937 monocytic cells. Prostaglandins & Other Lipid Mediators. 79: 126-40. PMID 16516816 DOI: 10.1016/J.Prostaglandins.2005.12.004  0.384
2006 Yishak AA, Costacou T, Virella G, Zgibor J, Fried L, Walsh M, Evans RW, Lopes-Virella M, Kagan VE, Otvos J, Orchard TJ. Novel predictors of overt nephropathy in subjects with type 1 diabetes. A nested case control study from the Pittsburgh Epidemiology of Diabetes Complications cohort. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 21: 93-100. PMID 16144851 DOI: 10.1093/Ndt/Gfi103  0.449
2005 Lopes-Virella MF, Thorpe SR, Derrick MB, Chassereau C, Virella G. The immunogenicity of modified lipoproteins. Annals of the New York Academy of Sciences. 1043: 367-78. PMID 16037258 DOI: 10.1196/Annals.1333.043  0.39
2005 Costacou T, Lopes-Virella MF, Zgibor JC, Virella G, Otvos J, Walsh M, Orchard TJ. Markers of endothelial dysfunction in the prediction of coronary artery disease in type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study. Journal of Diabetes and Its Complications. 19: 183-93. PMID 15993351 DOI: 10.1016/J.Jdiacomp.2005.01.003  0.432
2005 Nareika A, He L, Game BA, Slate EH, Sanders JJ, London SD, Lopes-Virella MF, Huang Y. Sodium lactate increases LPS-stimulated MMP and cytokine expression in U937 histiocytes by enhancing AP-1 and NF-kappaB transcriptional activities. American Journal of Physiology. Endocrinology and Metabolism. 289: E534-42. PMID 15941782 DOI: 10.1152/Ajpendo.00462.2004  0.388
2005 Kraml PJ, Klein RL, Huang Y, Nareika A, Lopes-Virella MF. Iron loading increases cholesterol accumulation and macrophage scavenger receptor I expression in THP-1 mononuclear phagocytes. Metabolism: Clinical and Experimental. 54: 453-9. PMID 15798950 DOI: 10.1016/J.Metabol.2004.10.012  0.313
2005 Virella G, Derrick MB, Pate V, Chassereau C, Thorpe SR, Lopes-Virella MF. Development of capture assays for different modifications of human low-density lipoprotein. Clinical and Diagnostic Laboratory Immunology. 12: 68-75. PMID 15642987 DOI: 10.1128/Cdli.12.1.68-75.2005  0.401
2005 Costacou T, Zgibor JC, Evans RW, Otvos J, Lopes-Virella MF, Tracy RP, Orchard TJ. The prospective association between adiponectin and coronary artery disease among individuals with type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study. Diabetologia. 48: 41-8. PMID 15616802 DOI: 10.1007/S00125-004-1597-Y  0.401
2004 Maldonado A, He L, Game BA, Nareika A, Sanders JJ, London SD, Lopes-Virella MF, Huang Y. Pre-exposure to high glucose augments lipopolysaccharide-stimulated matrix metalloproteinase-1 expression by human U937 histiocytes. Journal of Periodontal Research. 39: 415-23. PMID 15491346 DOI: 10.1111/J.1600-0765.2004.00756.X  0.326
2004 Virella G, Thorpe SR, Alderson NL, Derrick MB, Chassereau C, Rhett JM, Lopes-Virella MF. Definition of the immunogenic forms of modified human LDL recognized by human autoantibodies and by rabbit hyperimmune antibodies. Journal of Lipid Research. 45: 1859-67. PMID 15258197 DOI: 10.1194/Jlr.M400095-Jlr200  0.362
2004 Lopes-Virella MF, Mironova M, Stephan E, Durazo-Arvizu R, Virella G. Role of simvastatin as an immunomodulator in type 2 diabetes. Diabetes Care. 27: 908-13. PMID 15047647 DOI: 10.2337/Diacare.27.4.908  0.45
2003 Lopes-Virella MF, Virella G. The role of immune and inflammatory processes in the development of macrovascular disease in diabetes. Frontiers in Bioscience : a Journal and Virtual Library. 8: s750-68. PMID 12957881 DOI: 10.2741/1141  0.485
2003 Virella G, Lopes-Virella MF. Lipoprotein autoantibodies: measurement and significance. Clinical and Diagnostic Laboratory Immunology. 10: 499-505. PMID 12853376 DOI: 10.1128/Cdli.10.4.499-505.2003  0.31
2003 Fu Y, Huang Y, Bandyopadhyay S, Virella G, Lopes-Virella MF. LDL immune complexes stimulate LDL receptor expression in U937 histiocytes via extracellular signal-regulated kinase and AP-1. Journal of Lipid Research. 44: 1315-21. PMID 12730303 DOI: 10.1194/Jlr.M200415-Jlr200  0.362
2003 Virella G, Thorpe SR, Alderson NL, Stephan EM, Atchley D, Wagner F, Lopes-Virella MF. Autoimmune response to advanced glycosylation end-products of human LDL. Journal of Lipid Research. 44: 487-93. PMID 12562876 DOI: 10.1194/Jlr.M200370-Jlr200  0.376
2002 Virella G, Atchley D, Koskinen S, Zheng D, Lopes-Virella MF. Proatherogenic and proinflammatory properties of immune complexes prepared with purified human oxLDL antibodies and human oxLDL. Clinical Immunology (Orlando, Fla.). 105: 81-92. PMID 12483997 DOI: 10.1006/Clim.2002.5269  0.388
2002 Vielma S, Virella G, Gorod A, Lopes-Virella M. Chlamydophila pneumoniae infection of human aortic endothelial cells induces the expression of FC gamma receptor II (FcgammaRII). Clinical Immunology (Orlando, Fla.). 104: 265-73. PMID 12217337 DOI: 10.1006/Clim.2002.5237  0.314
2002 Eckel RH, Wassef M, Chait A, Sobel B, Barrett E, King G, Lopes-Virella M, Reusch J, Ruderman N, Steiner G, Vlassara H. Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group II: pathogenesis of atherosclerosis in diabetes Circulation. 105: e138-143. PMID 11994264 DOI: 10.1161/01.Cir.0000013954.65303.C5  0.346
2001 Klein RL, Scenção JL, Mironova M, Huang Y, Lopes-Virella MF. Effect of inflammatory cytokines on the metabolism of low-density lipoproteins by human vascular endothelial cells Metabolism: Clinical and Experimental. 50: 99-106. PMID 11172482 DOI: 10.1053/Meta.2001.19446  0.342
2000 Huang Y, Fleming AJ, Wu S, Virella G, Lopes-Virella MF. Fc-γ receptor cross-linking by immune complexes induces matrix metalloproteinase-1 in U937 cells via mitogen-activated protein kinase Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2533-2538. PMID 11116049 DOI: 10.1161/01.Atv.20.12.2533  0.37
2000 Lopes-Virella MF, Koskinen S, Mironova M, Horne D, Klein R, Chassereau C, Enockson C, Virella G. The preparation of copper-oxidized LDL for the measurement of oxidized LDL antibodies by EIA Atherosclerosis. 152: 107-115. PMID 10996345 DOI: 10.1016/S0021-9150(99)00456-6  0.302
2000 Mironova MA, Klein RL, Virella GT, Lopes-Virella MF. Anti-modified LDL antibodies, LDL-containing immune complexes, and susceptibility of LDL to in vitro oxidation in patients with type 2 diabetes Diabetes. 49: 1033-1041. PMID 10866057 DOI: 10.2337/Diabetes.49.6.1033  0.467
2000 Virella G, Koskinen S, Krings G, Onorato JM, Thorpe SR, Lopes-Virella M. Immunochemical characterization of purified human oxidized low-density lipoprotein antibodies. Clinical Immunology (Orlando, Fla.). 95: 135-44. PMID 10779407 DOI: 10.1006/Clim.2000.4857  0.313
1999 Huang Y, Mironova M, Lopes-Virella MF. Oxidized LDL stimulates matrix metalloproteinase-1 expression in human vascular endothelial cells Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2640-2647. PMID 10559006 DOI: 10.1161/01.Atv.19.11.2640  0.323
1999 Huang Y, Jaffa A, Koskinen S, Takei A, Lopes-Virella MF. Oxidized LDL-containing immune complexes induce Fc gamma receptor I- mediated mitogen-activated protein kinase activation in THP-1 macrophages Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 1600-1607. PMID 10397676 DOI: 10.1161/01.Atv.19.7.1600  0.346
1999 Orchard TJ, Virella G, Forrest KYZ, Evans RW, Becker DJ, Lopes-Virella MF. Antibodies to oxidized LDL predict coronary artery disease in type 1 diabetes: A nested case-control study from the Pittsburgh epidemiology of diabetes complications study Diabetes. 48: 1454-1458. PMID 10389853 DOI: 10.2337/Diabetes.48.7.1454  0.385
1999 Lopes-Virella MF, Virella G, Orchard TJ, Koskinen S, Evans RW, Becker DJ, Forrest KYZ. Antibodies to oxidized LDL and LDL-containing immune complexes as risk factors for coronary artery disease in diabetes mellitus Clinical Immunology. 90: 165-172. PMID 10080827 DOI: 10.1006/Clim.1998.4631  0.43
1997 Lopes-Virella MF, Binzafar N, Rackley S, Takei A, La Via M, Virella G. The uptake of LDL-IC by human macrophages: Predominant involvement of the FcγRI receptor Atherosclerosis. 135: 161-170. PMID 9430365 DOI: 10.1016/S0021-9150(97)00157-3  0.389
1997 Mironova M, Virella G, Virella-Lowell I, Lopes-Virella MF. Anti-modified LDL antibodies and LDL-containing immune complexes in IDDM patients and healthy controls Clinical Immunology and Immunopathology. 85: 73-82. PMID 9325072 DOI: 10.1006/Clin.1997.4404  0.462
1997 Lopes-Virella MF, Mironova M, Virella G. LDL-containing immune complexes and atherosclerosis in diabetes Diabetes Reviews. 5: 410-424.  0.406
1996 Lopes-Virella MF, Virella G. Modified lipoproteins, cytokines and macrovascular disease in non-insulin-dependent diabetes mellitus Annals of Medicine. 28: 347-354. PMID 8862690 DOI: 10.3109/07853899608999092  0.469
1996 Lopes-Virella MF, Klein RL, Virella G. Modification of lipoproteins in diabetes Diabetes/Metabolism Reviews. 12: 69-90. PMID 8861502 DOI: 10.1002/(SICI)1099-0895(199603)12:1<69::AID-DMR156>3.0.CO;2-B  0.336
1996 Lopes-Virella MF, Virella G. Cytokines, modified lipoproteins, and arteriosclerosis in diabetes Diabetes. 45. PMID 8674888 DOI: 10.2337/Diab.45.3.S40  0.484
1996 Jenkins AJ, Klein RL, Chassereau CN, Hermayer KL, Lopes-Virella MF. LDL from patients with well-controlled IDDM is not more susceptible to in vitro oxidation Diabetes. 45: 762-767. PMID 8635650 DOI: 10.2337/Diab.45.6.762  0.402
1996 Mironova M, Virella G, Lopes-Virella MF. Isolation and characterization of human antioxidized LDL autoantibodies Arteriosclerosis, Thrombosis, and Vascular Biology. 16: 222-229. PMID 8620336 DOI: 10.1161/01.Atv.16.2.222  0.339
1995 Virella G, Muñoz JF, Galbraith GM, Gissinger C, Chassereau C, Lopes-Virella MF. Activation of human monocyte-derived macrophages by immune complexes containing low-density lipoprotein. Clinical Immunology and Immunopathology. 75: 179-89. PMID 7704977 DOI: 10.1006/Clin.1995.1069  0.395
1995 Klein RL, Laimins M, Lopes-Virella MF. Isolation, characterization, and metabolism of the glycated and nonglycated subfractions of low-density lipoproteins isolated from type I diabetic patients and nondiabetic subjects Diabetes. 44: 1093-1098. PMID 7657034 DOI: 10.2337/Diab.44.9.1093  0.435
1995 Jokl R, Klein RL, Lopes-Virella MF, Colwell JA. Release of platelet plasminogen activator inhibitor 1 in whole blood is increased in patients with type II diabetes Diabetes Care. 18: 1150-1155. PMID 7587850 DOI: 10.2337/Diacare.18.8.1150  0.388
1994 Jokl R, Laimins M, Klein RL, Lyons TJ, Lopes-Virella MF, Colwell JA. Platelet plasminogen activator inhibitor 1 in patients with type II diabetes Diabetes Care. 17: 818-823. PMID 7956624 DOI: 10.2337/Diacare.17.8.818  0.385
1994 Lopes-Virella MF, Virella G. Atherosclerosis and autoimmunity Clinical Immunology and Immunopathology. 73: 155-167. PMID 7923923 DOI: 10.1006/Clin.1994.1184  0.432
1993 Virella G, Virella I, Leman RB, Pryor MB, Lopes-Virella MF. Anti-oxidized low-density lipoprotein antibodies in patients with coronary heart disease and normal healthy volunteers International Journal of Clinical &Amp; Laboratory Research. 23: 95-101. PMID 8518420 DOI: 10.1007/Bf02592290  0.343
1993 Klein RL, Lopes-Virella MF. Metabolism by human endothelial cells of very low density lipoprotein subfractions isolated from Type 1 (insulin-dependent) diabetic patients Diabetologia. 36: 258-264. PMID 8462776 DOI: 10.1007/Bf00399960  0.409
1992 Lopes-Virella MF, Virella G. Lipoproteins and immune responses in the vascular wall and their contribution to atherosclerosis in diabetes Metabolism. 41: 11-15. PMID 1574007 DOI: 10.1016/0026-0495(92)90087-Q  0.425
1992 Gisinger C, Lopes-Virella MF. Lipoprotein-immune complexes and diabetic vascular complications Diabetes. 41: 92-96. PMID 1526344 DOI: 10.2337/Diab.41.2.S92  0.437
1992 Lopes-Virella MF, Virella G. Immune mechanisms of atherosclerosis in diabetes mellitus Diabetes. 41: 86-91. PMID 1526343 DOI: 10.2337/Diab.41.2.S86  0.474
1992 Klein RL, Wohltmann HJ, Lopes-Virella MF. Influence of glycemic control on interaction of very-low- and low-density lipoproteins isolated from type I diabetic patients with human monocyte- derived macrophages Diabetes. 41: 1301-1307. PMID 1397704 DOI: 10.2337/Diab.41.10.1301  0.407
1991 Gisinger C, Virella GT, Lopes-Virella MF. Erythrocyte-bound low-density lipoprotein immune complexes lead to cholesteryl ester accumulation in human monocyte-derived macrophages Clinical Immunology and Immunopathology. 59: 37-52. PMID 2019010 DOI: 10.1016/0090-1229(91)90080-T  0.41
1991 Lopes-Virella MF, Griffith RL, Shunk KA, Virella GT. Enhanced uptake and impaired intracellular metabolism of low density lipoprotein complexed with anti-low density lipoprotein antibodies. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 11: 1356-67. PMID 1911721 DOI: 10.1161/01.Atv.11.5.1356  0.408
1990 Klein RL, Lyons TJ, Lopes-Virella MF. Metabolism of very low- and low-density lipoproteins isolated from normolipidaemic Type 2 (non-insulin-dependent) diabetic patients by human monocyte-derived macrophages Diabetologia. 33: 299-305. PMID 2376301 DOI: 10.1007/BF00403324  0.357
1989 Marken PA, Weart CW, Carson DS, Gums JG, Lopes-Virella MF. Effects of magnesium oxide on the lipid profile of healthy volunteers. Atherosclerosis. 77: 37-42. PMID 2719760 DOI: 10.1016/0021-9150(89)90007-5  0.353
1989 Klein RL, Lyons TJ, Lopes-Virella MF. Interaction of very-low-density lipoprotein isolated from type I (insulin-dependent) diabetic subjects with human monocyte-derived macrophages Metabolism. 38: 1108-1114. PMID 2554094 DOI: 10.1016/0026-0495(89)90048-6  0.338
1988 Watanabe J, Wohltmann HJ, Klein RL, Colwell JA, Lopes-Virella MF. Enhancement of platelet aggregation by low-density lipoproteins from IDDM patients Diabetes. 37: 1652-1657. PMID 3192039 DOI: 10.2337/Diab.37.12.1652  0.383
1988 Griffith RL, Virella GT, Stevenson HC, Lopes-Virella MF. Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes. A possible mechanism of foam cell formation. The Journal of Experimental Medicine. 168: 1041-59. PMID 3171477 DOI: 10.1084/Jem.168.3.1041  0.419
1988 Colwell JA, Lopes-Virella MF. A review of the development of large-vessel disease in diabetes mellitus The American Journal of Medicine. 85: 113-118. PMID 3057888 DOI: 10.1016/0002-9343(88)90403-2  0.434
1987 Lyons TJ, Klein RL, Baynes JW, Stevenson HC, Lopes-Virella MF. Stimulation of cholesteryl ester synthesis in human monocyte-derived macrophages by low-density lipoproteins from type 1 (insulin-dependent) diabetic patients: the influence of non-enzymatic glycosylation of low-density lipoproteins. Diabetologia. 30: 916-23. PMID 3436488 DOI: 10.1007/Bf00295874  0.474
1987 Lopes-Virella MF. Metabolism of lipoproteins in diabetes mellitus Journees Annuelles De Diabetologie De L"Hotel-Dieu. 55-66. PMID 3302494  0.303
1987 Lopes-Virella MF, Klein RL, Stevenson HC. Low density lipoprotein metabolism in human macrophages stimulated with microbial or microbial-related products. Arteriosclerosis (Dallas, Tex.). 7: 176-84. PMID 3107536 DOI: 10.1161/01.Atv.7.2.176  0.358
1986 Lyons TJ, Baynes JW, Patrick JS, Colwell JA, Lopes-Virella MF. Glycosylation of low density lipoprotein in patients with Type I (insulin-dependent) diabetes: Correlations with other parameters of glycaemic control Diabetologia. 29: 685-689. PMID 3803742 DOI: 10.1007/Bf00870276  0.314
1985 Mayfield RK, Halushka PV, Wohltmann HJ, Lopes-Virella M, Chambers JK, Loadholt CB, Colwell JA. Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients. Diabetes. 34: 1127-33. PMID 3930325 DOI: 10.2337/Diab.34.11.1127  0.314
1985 Lopes-Virella MF, Sherer G, Wohltmann H, Sens D, Colwell JA. Diabetic lipoprotein deficient serum: Its effect in low density lipoprotein (LDL) uptake and degradation by fibroblasts Metabolism. 34: 1079-1085. PMID 2999561 DOI: 10.1016/0026-0495(85)90150-7  0.474
1983 Colwell JA, Winocour PD, Lopes-Virella M, Halushka PV. New concepts about the pathogenesis of atherosclerosis in diabetes mellitus The American Journal of Medicine. 75: 67-80. PMID 6424441 DOI: 10.1016/0002-9343(83)90256-5  0.473
1983 Lopes-Virella MF, Wohltmann HJ, Mayfield RK, Loadholt CB, Colwell JA. Effect of metabolic control on lipid, lipoprotein, and apolipoprotein levels in 55 insulin-dependent diabetic patients. A longitudinal study Diabetes. 32: 20-25. PMID 6336700 DOI: 10.2337/Diab.32.1.20  0.399
1982 Lopes-Virella MF, Sherer GK, Lees AM, Wohltmann H, Mayfield R, Sagel J, LeRoy EC, Colwell JA. Surface binding, internalization and degradation by cultured human fibroblasts of low density lipoproteins isolated from Type 1 (insulin-dependent) diabetic patients: Changes with metabolic control Diabetologia. 22: 430-436. PMID 7049800 DOI: 10.1007/Bf00282585  0.424
1981 Lopes-Virella MF, Wohltmann HJ, Loadholt CB, Buse MG. Plasma lipids and lipoproteins in young insulin-dependent diabetic patients: Relationship with control Diabetologia. 21: 216-223. PMID 7297793 DOI: 10.1007/Bf00252657  0.394
1981 Colwell JA, Lopes-Virella M, Halushka PV. Pathogenesis of Atherosclerosis in Diabetes Mellitus Diabetes Care. 4: 121-133. PMID 7009108 DOI: 10.2337/Diacare.4.1.121  0.462
1979 Colwell JA, Halushka PV, Sarji KE, Lopes-Virella MF, Sagel J. Vascular disease in diabetes. Pathophysiological mechanisms and therapy Archives of Internal Medicine. 139: 225-230. PMID 434977 DOI: 10.1001/Archinte.1979.03630390077027  0.401
1979 Lopes-Virella MF, Virella G, Rosebrock G, Sagel J, Gonzalez J, Colwell J. Early diagnosis of renal malfunction in diabetics - Abnormal proteinuria revealed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis Diabetologia. 16: 165-171. PMID 428686 DOI: 10.1007/Bf01219793  0.408
1979 Sagel J, Lopes-Virella MF, Levine JH, Colwell JA. Decreased high density lipoprotein cholesterol in hypopituitarism. The Journal of Clinical Endocrinology and Metabolism. 49: 753-6. PMID 226560 DOI: 10.1210/Jcem-49-5-753  0.351
1979 Lopes-Virella M, Virella G, Debeukelaer M, Owens CJ, Colwell JA. Urinary high density lipoprotein in minimal change glomerular disease and chronic glomerulopathies Clinica Chimica Acta. 94: 73-81. PMID 222512 DOI: 10.1016/0009-8981(79)90187-6  0.347
1978 Virella G, Lopes-Virella MF, Levine J, Ogawa M, Gonzalez J. Idiopathic’ bence-jones proteinuria Acta Haematologica. 60: 269-279. PMID 101013 DOI: 10.1159/000207723  0.333
1976 Lopes-Virella MF, Sarji K, Virella G, Colwell JA. Platelet lipoproteins a comparative study with serum lipoproteins Bba - Protein Structure. 439: 339-348. PMID 182240 DOI: 10.1016/0005-2795(76)90069-6  0.309
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