Year |
Citation |
Score |
2018 |
Indurthi DC, Qudah T, Liao VW, Ahring PK, Lewis TM, Balle T, Chebib M, Absalom NL. Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry. Pharmacological Research. PMID 30472464 DOI: 10.1016/J.Phrs.2018.11.031 |
0.374 |
|
2016 |
Indurthi DC, Lewis TM, Ahring PK, Balle T, Chebib M, Absalom NL. Ligand Binding at the 4-4 Agonist-Binding Site of the 42 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State. Plos One. 11: e0161154. PMID 27552221 DOI: 10.1371/Journal.Pone.0161154 |
0.34 |
|
2015 |
Carland JE, Yamamoto I, Hanrahan JR, Abdel-Halim H, Lewis TM, Absalom N, Chebib M. A hydrophobic area of the GABA ρ₁ receptor containing phenylalanine 124 influences both receptor activation and deactivation. Journal of Molecular Neuroscience : Mn. 55: 305-13. PMID 24816654 DOI: 10.1007/S12031-014-0322-7 |
0.386 |
|
2015 |
Moorhouse AJ, Lewis TM, Barry PH. Analyzing Ion Permeation in Channels and Pumps Using Patch-Clamp Recording Pumps, Channels and Transporters: Methods of Functional Analysis. 51-88. DOI: 10.1002/9781119085126.ch3 |
0.349 |
|
2013 |
Absalom NL, Quek G, Lewis TM, Qudah T, von Arenstorff I, Ambrus JI, Harpsøe K, Karim N, Balle T, McLeod MD, Chebib M. Covalent trapping of methyllycaconitine at the α4-α4 interface of the α4β2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed. The Journal of Biological Chemistry. 288: 26521-32. PMID 23893416 DOI: 10.1074/Jbc.M113.475053 |
0.426 |
|
2012 |
Huang SH, Lewis TM, Lummis SC, Thompson AJ, Chebib M, Johnston GA, Duke RK. Mixed antagonistic effects of the ginkgolides at recombinant human Ï1 GABAC receptors. Neuropharmacology. 63: 1127-39. PMID 22828636 DOI: 10.1016/J.Neuropharm.2012.06.067 |
0.389 |
|
2010 |
Cederholm JM, Absalom NL, Sugiharto S, Griffith R, Schofield PR, Lewis TM. Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor. Journal of Neurochemistry. 115: 1245-55. PMID 20874766 DOI: 10.1111/J.1471-4159.2010.07021.X |
0.605 |
|
2010 |
Sugiharto S, Carland JE, Lewis TM, Moorhouse AJ, Barry PH. External divalent cations increase anion-cation permeability ratio in glycine receptor channels. Pflã¼Gers Archiv : European Journal of Physiology. 460: 131-52. PMID 20198385 DOI: 10.1007/S00424-010-0792-6 |
0.441 |
|
2010 |
Barry PH, Sugiharto S, Lewis TM, Moorhouse AJ. Further analysis of counterion permeation through anion-selective glycine receptor channels. Channels (Austin, Tex.). 4: 142-9. PMID 20139710 DOI: 10.4161/Chan.4.3.11020 |
0.469 |
|
2009 |
Cederholm JM, Schofield PR, Lewis TM. Gating mechanisms in Cys-loop receptors. European Biophysics Journal : Ebj. 39: 37-49. PMID 19404635 DOI: 10.1007/S00249-009-0452-Y |
0.585 |
|
2009 |
Absalom NL, Schofield PR, Lewis TM. Pore structure of the Cys-loop ligand-gated ion channels. Neurochemical Research. 34: 1805-15. PMID 19381804 DOI: 10.1007/S11064-009-9971-2 |
0.614 |
|
2009 |
Carland JE, Cooper MA, Sugiharto S, Jeong HJ, Lewis TM, Barry PH, Peters JA, Lambert JJ, Moorhouse AJ. Characterization of the effects of charged residues in the intracellular loop on ion permeation in alpha1 glycine receptor channels. The Journal of Biological Chemistry. 284: 2023-30. PMID 19049967 DOI: 10.1074/Jbc.M806618200 |
0.551 |
|
2008 |
Sugiharto S, Lewis TM, Moorhouse AJ, Schofield PR, Barry PH. Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels. Biophysical Journal. 95: 4698-715. PMID 18708455 DOI: 10.1529/Biophysj.107.125690 |
0.585 |
|
2006 |
Qu W, Moorhouse AJ, Chandra M, Pierce KD, Lewis TM, Barry PH. A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel. The Journal of General Physiology. 127: 375-89. PMID 16533895 DOI: 10.1085/Jgp.200509378 |
0.505 |
|
2005 |
Qu W, Moorhouse AJ, Lewis TM, Pierce KD, Barry PH. Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel. European Biophysics Journal : Ebj. 34: 442-53. PMID 15928936 DOI: 10.1007/S00249-005-0479-7 |
0.496 |
|
2004 |
Morris R, Morgan BS, Lewis TM, Pierce KD, Pisano A, Schofield PR. In vivo somatic delivery of plasmid DNA and retrograde transport to obtain cell-specific gene expression in the central nervous system. Journal of Neurochemistry. 90: 1445-52. PMID 15341528 DOI: 10.1111/J.1471-4159.2004.02612.X |
0.45 |
|
2004 |
Absalom NL, Lewis TM, Schofield PR. Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure. Experimental Physiology. 89: 145-53. PMID 15123543 DOI: 10.1113/Expphysiol.2003.026815 |
0.621 |
|
2003 |
Absalom NL, Lewis TM, Kaplan W, Pierce KD, Schofield PR. Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor. The Journal of Biological Chemistry. 278: 50151-7. PMID 14525990 DOI: 10.1074/Jbc.M305357200 |
0.628 |
|
2003 |
Lewis TM, Schofield PR, McClellan AM. Kinetic determinants of agonist action at the recombinant human glycine receptor. The Journal of Physiology. 549: 361-74. PMID 12679369 DOI: 10.1113/Jphysiol.2002.037796 |
0.532 |
|
2002 |
Rees MI, Lewis TM, Kwok JB, Mortier GR, Govaert P, Snell RG, Schofield PR, Owen MJ. Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB). Human Molecular Genetics. 11: 853-60. PMID 11929858 DOI: 10.1093/Hmg/11.7.853 |
0.544 |
|
2001 |
Rees MI, Lewis TM, Vafa B, Ferrie C, Corry P, Muntoni F, Jungbluth H, Stephenson JB, Kerr M, Snell RG, Schofield PR, Owen MJ. Compound heterozygosity and nonsense mutations in the alpha(1)-subunit of the inhibitory glycine receptor in hyperekplexia. Human Genetics. 109: 267-70. PMID 11702206 DOI: 10.1007/S004390100569 |
0.546 |
|
1999 |
Vafa B, Lewis TM, Cunningham AM, Jacques P, Lynch JW, Schofield PR. Identification of a new ligand binding domain in the alpha1 subunit of the inhibitory glycine receptor. Journal of Neurochemistry. 73: 2158-66. PMID 10537076 |
0.523 |
|
1999 |
Lewis TM, Schofield PR. Structure-function relationships of the human glycine receptor: insights from hyperekplexia mutations. Annals of the New York Academy of Sciences. 868: 681-4. PMID 10414353 DOI: 10.1111/J.1749-6632.1999.Tb11345.X |
0.501 |
|
1998 |
Lewis TM, Sivilotti LG, Colquhoun D, Gardiner RM, Schoepfer R, Rees M. Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes. The Journal of Physiology. 507: 25-40. PMID 9490812 DOI: 10.1111/J.1469-7793.1998.025Bu.X |
0.721 |
|
1997 |
Lewis TM, Harkness PC, Sivilotti LG, Colquhoun D, Millar NS. The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. The Journal of Physiology. 505: 299-306. PMID 9423173 DOI: 10.1111/J.1469-7793.1997.299Bb.X |
0.697 |
|
1997 |
Sivilotti LG, McNeil DK, Lewis TM, Nassar MA, Schoepfer R, Colquhoun D. Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour. The Journal of Physiology. 500: 123-38. PMID 9097938 DOI: 10.1113/Jphysiol.1997.Sp022004 |
0.707 |
|
1994 |
Lewis TM, Roberts ML, Bretag AH. Immunolabelling for VDAC, the mitochondrial voltage-dependent anion channel, on sarcoplasmic reticulum from amphibian skeletal muscle. Neuroscience Letters. 181: 83-6. PMID 7898777 DOI: 10.1016/0304-3940(94)90565-7 |
0.386 |
|
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