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Peter R. Schofield, PhD, DSc - Publications

Affiliations: 
Neuroscience Research Australia 
Website:
http://www.neura.edu.au/about/governance/prof-peter-schofield
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Year Citation  Score
2024 Ou AH, Rosenthal SB, Adli M, Akiyama K, Akula N, Alda M, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Bauer M, Baune BT, Bellivier F, Benabarre A, ... ... Schofield PR, et al. Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study. Translational Psychiatry. 14: 109. PMID 38395906 DOI: 10.1038/s41398-024-02811-4  0.574
2023 Herrera-Rivero M, Adli M, Akiyama K, Akula N, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Bellivier F, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, ... ... Schofield PR, et al. Exploring the genetics of lithium response in bipolar disorders. Research Square. PMID 38077040 DOI: 10.21203/rs.3.rs-3677630/v1  0.581
2023 Kelsoe J, Ou A, Rosenthal S, Adli M, Akiyama K, Akula N, Alda M, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, Banzato C, Bauer M, Baune B, ... ... Schofield P, et al. Lithium Response in Bipolar Disorder is Associated with Focal Adhesion and PI3K-Akt Networks: A Multi-omics Replication Study. Research Square. PMID 37886563 DOI: 10.21203/rs.3.rs-3258813/v1  0.574
2023 Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, ... ... Schofield PR, et al. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. The American Journal of Psychiatry. 180: 723-738. PMID 37777856 DOI: 10.1176/appi.ajp.21121266  0.558
2023 Herrera-Rivero M, Gutiérrez-Fragoso K, Thalamuthu A, Amare AT, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Aubry JM, Backlund L, Bellivier F, Benabarre A, Bengesser S, Abesh B, ... ... Schofield P, et al. Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder. Research Square. PMID 37461719 DOI: 10.21203/rs.3.rs-3068352/v1  0.583
2023 Amare AT, Thalamuthu A, Schubert KO, Fullerton JM, Ahmed M, Hartmann S, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hou L, Hsu YH, Shekhtman T, Adli M, Akula N, ... ... Schofield PR, et al. Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder. Molecular Psychiatry. PMID 37433967 DOI: 10.1038/s41380-023-02149-1  0.586
2023 Zwicker A, Fullerton JM, Mullins N, Rice F, Hafeman DM, van Haren NEM, Setiaman N, Merranko JA, Goldstein BI, Ferrera AG, Stapp EK, de la Serna E, Moreno D, Sugranyes G, Herrero SM, ... ... Schofield PR, et al. Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents. The American Journal of Psychiatry. appiajp20220476. PMID 36856707 DOI: 10.1176/appi.ajp.20220476  0.579
2023 McWhinney SR, Abé C, Alda M, Benedetti F, Bøen E, Del Mar Bonnin C, Borgers T, Brosch K, Canales-Rodríguez EJ, Cannon DM, Dannlowski U, Diaz-Zuluaga AM, Dietze LMF, Elvsåshagen T, Eyler LT, ... ... Schofield PR, et al. Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants. Psychological Medicine. 1-11. PMID 36846964 DOI: 10.1017/S0033291723000223  0.537
2023 Amare A, Thalamuthu A, Schubert KO, Fullerton J, Ahmed M, Hartmann S, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hou L, Hsu YH, Shekhtman T, Adli M, Akula N, ... ... Schofield P, et al. Association of Polygenic Score and the involvement of Cholinergic and Glutamatergic Pathways with Lithium Treatment Response in Patients with Bipolar Disorder. Research Square. PMID 36824922 DOI: 10.21203/rs.3.rs-2580252/v1  0.589
2022 Hesam-Shariati S, Overs BJ, Roberts G, Toma C, Watkeys OJ, Green MJ, Pierce KD, Edenberg HJ, Wilcox HC, Stapp EK, McInnis MG, Hulvershorn LA, Nurnberger JI, Schofield PR, Mitchell PB, et al. Epigenetic signatures relating to disease-associated genotypic burden in familial risk of bipolar disorder. Translational Psychiatry. 12: 310. PMID 35922419 DOI: 10.1038/s41398-022-02079-6  0.603
2022 Schubert KO, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, ... ... Schofield PR, et al. Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry. 12: 278. PMID 35817769 DOI: 10.1038/s41398-022-02037-2  0.584
2022 Cearns M, Amare AT, Schubert KO, Thalamuthu A, Frank J, Streit F, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry J, Backlund L, Bhattacharjee AK, Bellivier F, ... ... Schofield PR, et al. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM. The British Journal of Psychiatry : the Journal of Mental Science. 1. PMID 35505515 DOI: 10.1192/bjp.2022.55  0.541
2022 Brouwer RM, Klein M, Grasby KL, Schnack HG, Jahanshad N, Teeuw J, Thomopoulos SI, Sprooten E, Franz CE, Gogtay N, Kremen WS, Panizzon MS, Olde Loohuis LM, Whelan CD, Aghajani M, ... ... Schofield PR, et al. Genetic variants associated with longitudinal changes in brain structure across the lifespan. Nature Neuroscience. PMID 35383335 DOI: 10.1038/s41593-022-01042-4  0.557
2022 Jamshidi J, Schofield PR, Gatt JM, Fullerton JM. Phenotypic and genetic analysis of a wellbeing factor score in the UK Biobank and the impact of childhood maltreatment and psychiatric illness. Translational Psychiatry. 12: 113. PMID 35304435 DOI: 10.1038/s41398-022-01874-5  0.584
2022 Cearns M, Amare AT, Schubert KO, Thalamuthu A, Frank J, Streit F, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, ... ... Schofield PR, et al. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach. The British Journal of Psychiatry : the Journal of Mental Science. 1-10. PMID 35225756 DOI: 10.1192/bjp.2022.28  0.565
2021 Coombes BJ, Millischer V, Batzler A, Larrabee B, Hou L, Papiol S, Heilbronner U, Adli M, Akiyama K, Akula N, Amare AT, Ardau R, Arias B, Aubry JM, Backlund L, ... ... Schofield PR, et al. Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study. Complex Psychiatry. 7: 80-89. PMID 36408127 DOI: 10.1159/000519707  0.586
2021 Kalman JL, Olde Loohuis LM, Vreeker A, McQuillin A, Stahl EA, Ruderfer D, Grigoroiu-Serbanescu M, Panagiotaropoulou G, Ripke S, Bigdeli TB, Stein F, Meller T, Meinert S, Pelin H, Streit F, ... ... Schofield PR, et al. Characterisation of age and polarity at onset in bipolar disorder. The British Journal of Psychiatry : the Journal of Mental Science. 219: 659-669. PMID 35048876 DOI: 10.1192/bjp.2021.102  0.575
2021 McWhinney SR, Abé C, Alda M, Benedetti F, Bøen E, Del Mar Bonnin C, Borgers T, Brosch K, Canales-Rodríguez EJ, Cannon DM, Dannlowski U, Diaz-Zuluaga AM, Dietze L, Elvsåshagen T, Eyler LT, ... ... Schofield PR, et al. Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness - ENIGMA study in 2 436 individuals. Bipolar Disorders. PMID 34894200 DOI: 10.1111/bdi.13172  0.546
2021 Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, ... ... Schofield PR, et al. Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biological Psychiatry. PMID 34861974 DOI: 10.1016/j.biopsych.2021.05.029  0.569
2021 Schubert KO, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, ... ... Schofield PR, et al. Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Translational Psychiatry. 11: 606. PMID 34845190 DOI: 10.1038/s41398-021-01702-2  0.608
2021 Overs BJ, Roberts G, Ridgway K, Toma C, Hadzi-Pavlovic D, Wilcox HC, Hulvershorn LA, Nurnberger JI, Schofield PR, Mitchell PB, Fullerton JM. Effects of polygenic risk for suicide attempt and risky behavior on brain structure in young people with familial risk of bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 34726322 DOI: 10.1002/ajmg.b.32879  0.578
2021 Le Clerc S, Lombardi L, Baune BT, Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, ... ... Schofield PR, et al. HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders. Scientific Reports. 11: 17823. PMID 34497278 DOI: 10.1038/s41598-021-97140-7  0.576
2021 Blokland GAM, Grove J, Chen CY, Cotsapas C, Tobet S, Handa R, St Clair D, Lencz T, Mowry BJ, Periyasamy S, Cairns MJ, Tooney PA, Wu JQ, Kelly B, ... ... Schofield PR, et al. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry. PMID 34099189 DOI: 10.1016/j.biopsych.2021.02.972  0.602
2021 Mullins N, Forstner AJ, O'Connell KS, Coombes B, Coleman JRI, Qiao Z, Als TD, Bigdeli TB, Børte S, Bryois J, Charney AW, Drange OK, Gandal MJ, Hagenaars SP, Ikeda M, ... ... Schofield PR, et al. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics. PMID 34002096 DOI: 10.1038/s41588-021-00857-4  0.611
2021 McWhinney SR, Abé C, Alda M, Benedetti F, Bøen E, Del Mar Bonnin C, Borgers T, Brosch K, Canales-Rodríguez EJ, Cannon DM, Dannlowski U, Díaz-Zuluaga AM, Elvsåshagen T, Eyler LT, Fullerton JM, ... ... Schofield PR, et al. Association between body mass index and subcortical brain volumes in bipolar disorders-ENIGMA study in 2735 individuals. Molecular Psychiatry. PMID 33863996 DOI: 10.1038/s41380-021-01098-x  0.544
2021 Toma C, Shaw AD, Heath A, Pierce KD, Mitchell PB, Schofield PR, Fullerton JM. A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21. Journal of Psychiatry & Neuroscience : Jpn. 46: E247-E257. PMID 33729739 DOI: 10.1503/jpn.200083  0.603
2021 Overs BJ, Lenroot RK, Roberts G, Green MJ, Toma C, Hadzi-Pavlovic D, Pierce KD, Schofield PR, Mitchell PB, Fullerton JM. Cortical mediation of relationships between dopamine receptor D2 and cognition is absent in youth at risk of bipolar disorder. Psychiatry Research. Neuroimaging. 309: 111258. PMID 33529975 DOI: 10.1016/j.pscychresns.2021.111258  0.586
2021 Stone W, Nunes A, Akiyama K, Akula N, Ardau R, Aubry JM, Backlund L, Bauer M, Bellivier F, Cervantes P, Chen HC, Chillotti C, Cruceanu C, Dayer A, Degenhardt F, ... ... Schofield PR, et al. Prediction of lithium response using genomic data. Scientific Reports. 11: 1155. PMID 33441847 DOI: 10.1038/s41598-020-80814-z  0.532
2020 de Zwarte SMC, Brouwer RM, Agartz I, Alda M, Alonso-Lana S, Bearden CE, Bertolino A, Bonvino A, Bramon E, Buimer EEL, Cahn W, Canales-Rodríguez EJ, Cannon DM, Cannon TD, Caseras X, ... ... Schofield PR, et al. Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder. Human Brain Mapping. PMID 33027543 DOI: 10.1002/hbm.25206  0.573
2020 Patel Y, Parker N, Shin J, Howard D, French L, Thomopoulos SI, Pozzi E, Abe Y, Abé C, ... ... Schofield PR, et al. Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders. Jama Psychiatry. PMID 32857118 DOI: 10.1001/Jamapsychiatry.2020.2694  0.563
2020 Jamshidi J, Williams LM, Schofield PR, Park HRP, Montalto A, Chilver MR, Bryant RA, Toma C, Fullerton JM, Gatt JM. Diverse phenotypic measurements of wellbeing: Heritability, temporal stability, and the variance explained by polygenic scores. Genes, Brain, and Behavior. e12694. PMID 32785990 DOI: 10.1111/Gbb.12694  0.582
2020 Armstrong NJ, Mather KA, Sargurupremraj M, Knol MJ, Malik R, Satizabal CL, Yanek LR, Wen W, Gudnason VG, Dueker ND, Elliott LT, Hofer E, Bis J, Jahanshad N, Li S, ... ... Schofield PR, et al. Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. Stroke. STROKEAHA119027544. PMID 32517579 DOI: 10.1161/Strokeaha.119.027544  0.312
2020 Chilver MR, Keller AS, Park HRP, Jamshidi J, Montalto A, Schofield PR, Clark CR, Harmon-Jones E, Williams LM, Gatt JM. Electroencephalography profiles as a biomarker of wellbeing: A twin study. Journal of Psychiatric Research. 126: 114-121. PMID 32450375 DOI: 10.1016/J.Jpsychires.2020.04.010  0.303
2020 Han LKM, Dinga R, Hahn T, Ching CRK, Eyler LT, Aftanas L, Aghajani M, Aleman A, Baune BT, Berger K, Brak I, Filho GB, Carballedo A, Connolly CG, Couvy-Duchesne B, ... ... Schofield PR, et al. Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group. Molecular Psychiatry. PMID 32424236 DOI: 10.1038/S41380-020-0754-0  0.59
2020 Toma C, Shaw AD, Overs BJ, Mitchell PB, Schofield PR, Cooper AA, Fullerton JM. De Novo Gene Variants and Familial Bipolar Disorder. Jama Network Open. 3: e203382. PMID 32383744 DOI: 10.1001/jamanetworkopen.2020.3382  0.585
2020 Meiser B, Guo XY, Putt S, Fullerton JM, Schofield PR, Mitchell PB, Yanes T. Psychosocial implications of living with familial risk of a psychiatric disorder and attitudes to psychiatric genetic testing: A systematic review of the literature. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32369270 DOI: 10.1002/Ajmg.B.32786  0.624
2020 Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Cearns M, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, ... ... Schofield PR, et al. Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry. PMID 32203155 DOI: 10.1038/S41380-020-0689-5  0.629
2020 Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, ... ... Schofield PR, et al. The genetic architecture of the human cerebral cortex. Science (New York, N.Y.). 367. PMID 32193296 DOI: 10.1126/Science.Aay6690  0.328
2020 Dobson-Stone C, Hallupp M, Shahheydari H, Ragagnin AMG, Chatterton Z, Carew-Jones F, Shepherd CE, Stefen H, Paric E, Fath T, Thompson EM, Blumbergs P, Short CL, Field CD, Panegyres PK, ... ... Schofield PR, et al. CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 32185393 DOI: 10.1093/Brain/Awaa039  0.62
2020 Putt S, Yanes T, Meiser B, Kaur R, Fullerton JM, Barlow-Stewart K, Schofield PR, Toma C, Peay H, Mitchell PB. Exploration of experiences with and understanding of polygenic risk scores for bipolar disorder. Journal of Affective Disorders. 265: 342-350. PMID 32090758 DOI: 10.1016/J.Jad.2020.01.037  0.629
2019 van der Meer D, Sønderby IE, Kaufmann T, Walters GB, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn NB, Blangero J, Boomsma DI, Brodaty H, ... ... Schofield PR, et al. Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition. Jama Psychiatry. 1-11. PMID 31665216 DOI: 10.1001/Jamapsychiatry.2019.3779  0.304
2019 Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, ... ... Schofield PR, et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. PMID 31636452 DOI: 10.1038/S41588-019-0511-Y  0.349
2019 de Zwarte SMC, Brouwer RM, Agartz I, Alda M, Aleman A, Alpert KI, Bearden CE, Bertolino A, Bois C, Bonvino A, Bramon E, Buimer EEL, Cahn W, Cannon DM, Cannon TD, ... ... Schofield PR, et al. The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder. Biological Psychiatry. PMID 31443932 DOI: 10.1016/J.Biopsych.2019.03.985  0.629
2019 Favre P, Pauling M, Stout J, Hozer F, Sarrazin S, Abé C, Alda M, Alloza C, Alonso-Lana S, Andreassen OA, Baune BT, Benedetti F, Busatto GF, Canales-Rodríguez EJ, Caseras X, ... ... Schofield PR, et al. Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31434102 DOI: 10.1038/S41386-019-0485-6  0.341
2019 Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, ... ... Schofield PR, et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics. PMID 31043756 DOI: 10.1038/S41588-019-0397-8  0.648
2019 Revelas M, Thalamuthu A, Oldmeadow C, Evans TJ, Armstrong NJ, Riveros C, Kwok JB, Schofield PR, Brodaty H, Scott RJ, Attia JR, Sachdev PS, Mather KA. Exceptional Longevity and Polygenic Risk for Cardiovascular Health. Genes. 10. PMID 30889929 DOI: 10.3390/Genes10030227  0.317
2019 Hesam-Shariati S, Overs B, Toma C, Watkeys O, Green M, Roberts G, Leung V, Stuart A, Schofield PR, Mitchell PB, Fullerton J. M49 EPIGENOME-WIDE ASSOCIATION STUDY (EWAS) OF YOUNG PEOPLE WITH FAMILIAL RISK OF BIPOLAR DISORDER European Neuropsychopharmacology. 29: S192. DOI: 10.1016/J.Euroneuro.2019.08.149  0.616
2019 Fullerton J, Roberts G, Overs B, Lenroot RK, Breakspear M, Frankland A, McInnis M, Glowinski A, Wilcox H, Stapp E, Hulvershorn L, Benke K, Schofield P, Nurnberger J, Mitchell PB. Su77Brain Cortical Trajectories, Polygenic Risk And Environmental Interactions In A Prospective Longitudinal Study Of Young People At-Risk Of Bipolar Disorder European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2018.08.441  0.602
2019 Overs BJ, Lenroot RK, Roberts G, Green MJ, Hadzi-Pavlovic D, Frankland A, Levy F, Toma C, Schofield PR, Mitchell PB, Fullerton J. The Relationship Between Functional Dopamine D2 Receptor Haplotypes And Cognitive Outcomes, As Mediated By Regional Brain Structure: A Comparison Of Control, At-Risk, And Bipolar Disorder Subjects European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.375  0.618
2019 Lenroot RK, Overs B, Roberts G, Frankland A, Levy F, Toma C, Wieckert CS, Schofield P, Mitchell P, Fullerton J. Interactive Effects Of Family History, Polygenic Risk And Age On Cortical Thickness In Young People At High Genetic Risk Of Bipolar Disorder European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.256  0.621
2019 Toma C, Shaw AD, Allcock RJ, Heath A, Pierce KD, Mitchell PB, Schofield PR, Fullerton JM. ADDRESSING THE IMPACT OF RARE GENETIC VARIANTS IN EXTENDED/MULTIPLEX BIPOLAR FAMILIES European Neuropsychopharmacology. 29: S837-S838. DOI: 10.1016/J.Euroneuro.2017.08.101  0.604
2019 Shaw A, Toma C, Allcock R, Heath A, Pierce K, Mitchell PB, Schofield P, Fullerton J. COMBINED WHOLE EXOME SEQUENCING AND LINKAGE ANALYSIS REVEALS LINKAGE TO 10Q11-10Q21 LOCUS WHICH IS NOT EXPLAINED BY GWAS-ASSOCIATED SNP OR RARE VARIANTS IN ANK3 European Neuropsychopharmacology. 29: S834-S835. DOI: 10.1016/J.Euroneuro.2017.08.096  0.646
2018 Toma C, Pierce KD, Shaw AD, Heath A, Mitchell PB, Schofield PR, Fullerton JM. Comprehensive cross-disorder analyses of CNTNAP2 suggest it is unlikely to be a primary risk gene for psychiatric disorders. Plos Genetics. 14: e1007535. PMID 30586385 DOI: 10.1371/Journal.Pgen.1007535  0.657
2018 Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, ... ... Schofield PR, et al. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nature Communications. 9: 3945. PMID 30258056 DOI: 10.1038/S41467-018-06234-W  0.337
2018 Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, Adli M, Adorjan K, Akula N, Alda M, Anderson-Schmidt H, Andlauer TF, Anghelescu IG, Ardau R, Arias B, ... ... Schofield PR, et al. Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study. Bipolar Disorders. PMID 29956436 DOI: 10.1111/Bdi.12659  0.643
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Schofield PR, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.644
2018 Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Benabarre A, ... ... Schofield PR, et al. Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder. Frontiers in Psychiatry. 9: 207. PMID 29904359 DOI: 10.3389/Fpsyt.2018.00207  0.584
2018 Revelas M, Thalamuthu A, Oldmeadow C, Evans TJ, Armstrong NJ, Kwok JB, Brodaty H, Schofield PR, Scott RJ, Sachdev PS, Attia JR, Mather KA. Review and meta-analysis of genetic polymorphisms associated with exceptional human longevity. Mechanisms of Ageing and Development. PMID 29890178 DOI: 10.1016/J.Mad.2018.06.002  0.311
2018 Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, ... ... Schofield PW, ... ... Schofield PR, et al. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. 9: 2098. PMID 29844566 DOI: 10.1038/S41467-018-04362-X  0.316
2018 Toma C, Shaw AD, Allcock RJN, Heath A, Pierce KD, Mitchell PB, Schofield PR, Fullerton JM. An examination of multiple classes of rare variants in extended families with bipolar disorder. Translational Psychiatry. 8: 65. PMID 29531218 DOI: 10.1038/S41398-018-0113-Y  0.644
2018 Fullerton JM, Klauser P, Lenroot RK, Shaw AD, Overs B, Heath A, Cairns MJ, Atkins J, Scott R, Schofield PR, Weickert CS, Pantelis C, Fornito A, Whitford TJ, et al. Differential effect of disease-associated ST8SIA2 haplotype on cerebral white matter diffusion properties in schizophrenia and healthy controls. Translational Psychiatry. 8: 21. PMID 29353880 DOI: 10.1038/S41398-017-0052-Z  0.603
2017 Xiao X, Wang L, Wang C, Yuan TF, Zhou D, Zheng F, Li L, Grigoroiu-Serbanescu M, Ikeda M, Iwata N, Takahashi A, Kamatani Y, Kubo M, Preisig M, Kutalik Z, ... ... Schofield PR, et al. Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders. Translational Psychiatry. 7: 1273. PMID 29225345 DOI: 10.1038/S41398-017-0019-0  0.37
2017 Mühleisen TW, Reinbold CS, Forstner AJ, Abramova LI, Alda M, Babadjanova G, Bauer M, Brennan P, Chuchalin A, Cruceanu C, Czerski PM, Degenhardt F, Fischer SB, Fullerton JM, Gordon SD, ... ... Schofield PR, et al. Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder. Journal of Affective Disorders. 228: 20-25. PMID 29197740 DOI: 10.1016/J.Jad.2017.11.068  0.631
2017 Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, ... ... Schofield PR, et al. Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study. Jama Psychiatry. PMID 29121268 DOI: 10.1001/Jamapsychiatry.2017.3433  0.637
2017 Corry J, Green M, Roberts G, Fullerton JM, Schofield PR, Mitchell PB. Does perfectionism in bipolar disorder pedigrees mediate associations between anxiety/stress and mood symptoms? International Journal of Bipolar Disorders. 5: 34. PMID 28983840 DOI: 10.1186/S40345-017-0102-8  0.593
2017 Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, ... ... Schofield PR, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Translational Psychiatry. 7: e1155. PMID 28632202 DOI: 10.1038/Tp.2017.115  0.651
2017 Hibar DP, Westlye LT, Doan NT, Jahanshad N, Cheung JW, Ching CRK, Versace A, Bilderbeck AC, Uhlmann A, Mwangi B, Krämer B, Overs B, Hartberg CB, Abé C, Dima D, ... ... Schofield PR, et al. Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry. PMID 28461699 DOI: 10.1038/Mp.2017.73  0.331
2017 Salminen LE, Schofield PR, Pierce KD, Bruce SE, Griffin MG, Tate DF, Cabeen RP, Laidlaw DH, Conturo TE, Bolzenius JD, Paul RH. Vulnerability of white matter tracts and cognition to the SOD2 polymorphism: A preliminary study of antioxidant defense genes in brain aging. Behavioural Brain Research. PMID 28457881 DOI: 10.1016/J.Bbr.2017.04.041  0.31
2017 Forstner AJ, Hecker J, Hofmann A, Maaser A, Reinbold CS, Mühleisen TW, Leber M, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Schumacher J, Streit F, Meier S, Herms S, ... ... Schofield PR, et al. Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. Plos One. 12: e0171595. PMID 28166306 DOI: 10.1371/Journal.Pone.0171595  0.646
2017 Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, ... ... Schofield PR, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/Ncomms13624  0.364
2017 Chang H, Hoshina N, Zhang C, Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Landén M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, ... ... Schofield PR, et al. The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Molecular Psychiatry. PMID 28070120 DOI: 10.1038/Mp.2016.231  0.398
2017 Green M, Girshkin L, O’Reilly N, Quidé Y, Rowland J, Schofield P. 118.4 Diurnal Cortisol Variation and Cortisol Response to an MRI Stressor in Schizophrenia and Bipolar Disorder Schizophrenia Bulletin. 43. DOI: 10.1093/Schbul/Sbx021.176  0.316
2017 Mitchell P, Frankland A, Roberts G, Holmes-Preston E, Perich T, Levy F, Lenroot R, Hadzi-Pavlovic D, Breakspear M, Fullerton J, Schofield P. Predicting Conversion To Bipolar Disorder In A Prospective Longitudinal Genetically High-Risk Sample European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.631  0.378
2017 McInnis M, Kelsoe J, Schofield P. THE DEVELOPING BRAIN DEVELOPING PSYCHOPATHOLOGY European Neuropsychopharmacology. 27: S514-S515. DOI: 10.1016/J.Euroneuro.2016.09.628  0.377
2016 Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, ... ... Schofield PR, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. PMID 27694991 DOI: 10.1038/Nn.4398  0.339
2016 Meiser B, Peate M, Levitan C, Mitchell PB, Trevena L, Barlow-Stewart K, Dobbins T, Christensen H, Sherman KA, Dunlop K, Schofield PR. A Psycho-Educational Intervention for People with a Family History of Depression: Pilot Results. Journal of Genetic Counseling. PMID 27688164 DOI: 10.1007/S10897-016-0011-5  0.314
2016 Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landén M, Adli M, Alda M, Ardau R, Arias B, Aubry JM, Backlund L, Badner JA, Barrett TB, Bauer M, ... ... Schofield PR, et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Human Molecular Genetics. PMID 27329760 DOI: 10.1093/Hmg/Ddw181  0.644
2016 Mather KA, Thalamuthu A, Oldmeadow C, Song F, Armstrong NJ, Poljak A, Holliday EG, McEvoy M, Kwok JB, Assareh AA, Reppermund S, Kochan NA, Lee T, Ames D, Wright MJ, ... ... Schofield PW, ... ... Schofield PR, et al. Genome-wide significant results identified for plasma apolipoprotein H levels in middle-aged and older adults. Scientific Reports. 6: 23675. PMID 27030319 DOI: 10.1038/Srep23675  0.311
2016 Girshkin L, O'Reilly N, Quidé Y, Teroganova N, Rowland JE, Schofield PR, Green MJ. Diurnal cortisol variation and cortisol response to an MRI stressor in schizophrenia and bipolar disorder. Psychoneuroendocrinology. 67: 61-69. PMID 26874562 DOI: 10.1016/J.Psyneuen.2016.01.021  0.318
2016 Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CE, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Birner A, ... ... Schofield PR, et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet (London, England). PMID 26806518 DOI: 10.1016/S0140-6736(16)00143-4  0.625
2015 Forstner AJ, Hofmann A, Maaser A, Sumer S, Khudayberdiev S, Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Schumacher J, Breuer R, Meier S, ... ... Schofield PR, et al. Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. Translational Psychiatry. 5: e678. PMID 26556287 DOI: 10.1038/Tp.2015.159  0.597
2015 Li M, Luo XJ, Landén M, Bergen SE, Hultman CM, Li X, Zhang W, Yao YG, Zhang C, Liu J, Mattheisen M, Cichon S, Mühleisen TW, Degenhardt FA, Nöthen MM, ... ... Schofield PR, et al. Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. The British Journal of Psychiatry : the Journal of Mental Science. PMID 26338991 DOI: 10.1192/Bjp.Bp.114.156976  0.652
2015 Fullerton JM, Koller DL, Edenberg HJ, Foroud T, Liu H, Glowinski AL, McInnis MG, Wilcox HC, Frankland A, Roberts G, Schofield PR, Mitchell PB, Nurnberger JI. Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 617-29. PMID 26178159 DOI: 10.1002/Ajmg.B.32344  0.634
2015 Ringman JM, Liang LJ, Zhou Y, Vangala S, Teng E, Kremen S, Wharton D, Goate A, Marcus DS, Farlow M, Ghetti B, McDade E, Masters CL, Mayeux RP, Rossor M, ... ... Schofield PR, et al. Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network. Brain : a Journal of Neurology. 138: 1036-45. PMID 25688083 DOI: 10.1093/Brain/Awv004  0.304
2015 Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, ... ... Schofield PW, ... ... Schofield PR, et al. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). Molecular Psychiatry. 20: 183-92. PMID 25644384 DOI: 10.1038/Mp.2014.188  0.337
2015 Chan JP, Thalamuthu A, Oldmeadow C, Armstrong NJ, Holliday EG, McEvoy M, Kwok JB, Assareh AA, Peel R, Hancock SJ, Reppermund S, Menant J, Trollor JN, Brodaty H, Schofield PR, et al. Genetics of hand grip strength in mid to late life. Age (Dordrecht, Netherlands). 37: 9745. PMID 25637336 DOI: 10.1007/S11357-015-9745-5  0.324
2015 Mather KA, Armstrong NJ, Wen W, Kwok JB, Assareh AA, Thalamuthu A, Reppermund S, Duesing K, Wright MJ, Ames D, Trollor JN, Brodaty H, Schofield PR, Sachdev PS. Investigating the genetics of hippocampal volume in older adults without dementia. Plos One. 10: e0116920. PMID 25625606 DOI: 10.1371/Journal.Pone.0116920  0.306
2015 Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, ... ... Schofield PR, et al. Common genetic variants influence human subcortical brain structures. Nature. 520: 224-9. PMID 25607358 DOI: 10.1038/Nature14101  0.33
2015 Gatt JM, Burton KL, Williams LM, Schofield PR. Specific and common genes implicated across major mental disorders: a review of meta-analysis studies. Journal of Psychiatric Research. 60: 1-13. PMID 25287955 DOI: 10.1016/J.Jpsychires.2014.09.014  0.402
2015 Fullerton JM, Koller DL, Edenberg HJ, Foroud T, Liu H, Glowinski AL, Mcinnis MG, Wilcox HC, Frankland A, Roberts G, Schofield PR, Mitchell PB, Nurnberger JI. Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young at-risk individuals American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. DOI: 10.1002/ajmg.b.32344  0.58
2014 Kanchibhotla SC, Mather KA, Thalamuthu A, Zhuang L, Schofield PR, Kwok JB, Ames D, Wright MJ, Trollor JN, Wen W, Sachdev PS. Genetics of microstructure of the corpus callosum in older adults. Plos One. 9: e113181. PMID 25514436 DOI: 10.1371/Journal.Pone.0113181  0.3
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, ... ... Schofield PR, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/Jamaneurol.2014.1654  0.309
2014 Salminen LE, Schofield PR, Pierce KD, Conturo TE, Tate DF, Lane EM, Heaps JM, Bolzenius JD, Baker LM, Akbudak E, Paul RH. Impact of the AGTR1 A1166C polymorphism on subcortical hyperintensities and cognition in healthy older adults. Age (Dordrecht, Netherlands). 36: 9664. PMID 24981111 DOI: 10.1007/S11357-014-9664-X  0.307
2014 Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, et al. Frontotemporal dementia and its subtypes: a genome-wide association study. The Lancet. Neurology. 13: 686-99. PMID 24943344 DOI: 10.1016/S1474-4422(14)70065-1  0.393
2014 Assareh AA, Piguet O, Lye TC, Mather KA, Broe GA, Schofield PR, Sachdev PS, Kwok JB. Association of SORL1 gene variants with hippocampal and cerebral atrophy and Alzheimer's disease. Current Alzheimer Research. 11: 558-63. PMID 24938503 DOI: 10.2174/1567205011666140618101408  0.302
2014 Zhou YZ, Wilde A, Meiser B, Mitchell PB, Barlow-Stewart K, Schofield PR. Attitudes of medical genetics practitioners and psychiatrists toward communicating with patients about genetic risk for psychiatric disorders. Psychiatric Genetics. 24: 94-101. PMID 24710128 DOI: 10.1097/Ypg.0000000000000030  0.37
2014 Wilde A, Chan HN, Rahman B, Meiser B, Mitchell PB, Schofield PR, Green MJ. A meta-analysis of the risk of major affective disorder in relatives of individuals affected by major depressive disorder or bipolar disorder. Journal of Affective Disorders. 158: 37-47. PMID 24655763 DOI: 10.1016/J.Jad.2014.01.014  0.354
2014 Shaw AD, Tiwari Y, Kaplan W, Heath A, Mitchell PB, Schofield PR, Fullerton JM. Characterisation of genetic variation in ST8SIA2 and its interaction region in NCAM1 in patients with bipolar disorder. Plos One. 9: e92556. PMID 24651862 DOI: 10.1371/Journal.Pone.0092556  0.646
2014 Assareh AA, Mather KA, Crawford JD, Wen W, Anstey KJ, Easteal S, Tan X, Mack HA, Kwok JB, Schofield PR, Sachdev PS. Renin-angiotensin system genetic polymorphisms and brain white matter lesions in older Australians. American Journal of Hypertension. 27: 1191-8. PMID 24622918 DOI: 10.1093/Ajh/Hpu035  0.3
2014 Mühleisen TW, Leber M, Schulze TG, Strohmaier J, Degenhardt F, Treutlein J, Mattheisen M, Forstner AJ, Schumacher J, Breuer R, Meier S, Herms S, Hoffmann P, Lacour A, Witt SH, ... ... Schofield PR, et al. Genome-wide association study reveals two new risk loci for bipolar disorder. Nature Communications. 5: 3339. PMID 24618891 DOI: 10.1038/Ncomms4339  0.636
2014 Vercammen A, Weickert CS, Skilleter AJ, Lenroot R, Schofield PR, Weickert TW. Common polymorphisms in dopamine-related genes combine to produce a 'schizophrenia-like' prefrontal hypoactivity. Translational Psychiatry. 4: e356. PMID 24495967 DOI: 10.1038/Tp.2013.125  0.302
2014 Quinn V, Meiser B, Wilde A, Cousins Z, Barlow-Stewart K, Mitchell PB, Schofield PR. Preferences regarding targeted education and risk assessment in people with a family history of major depressive disorder. Journal of Genetic Counseling. 23: 785-95. PMID 24407933 DOI: 10.1007/S10897-013-9685-0  0.325
2014 Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, ... ... Schofield PR, et al. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. 8: 153-82. PMID 24399358 DOI: 10.1007/S11682-013-9269-5  0.356
2014 Loy CT, Schofield PR, Turner AM, Kwok JB. Genetics of dementia. Lancet. 383: 828-40. PMID 23927914 DOI: 10.1016/S0140-6736(13)60630-3  0.318
2014 Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, ... ... Schofield PR, et al. Common variant at 16p11.2 conferring risk of psychosis. Molecular Psychiatry. 19: 108-14. PMID 23164818 DOI: 10.1038/Mp.2012.157  0.637
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, ... Schofield PR, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/Wnl.0B013E3182A841C6  0.307
2013 Dobson-Stone C, Polly P, Korgaonkar MS, Williams LM, Gordon E, Schofield PR, Mather K, Armstrong NJ, Wen W, Sachdev PS, Kwok JB. GSK3B and MAPT polymorphisms are associated with grey matter and intracranial volume in healthy individuals. Plos One. 8: e71750. PMID 23951236 DOI: 10.1371/Journal.Pone.0071750  0.331
2013 Manchia M, Adli M, Akula N, Ardau R, Aubry JM, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng AT, ... ... Schofield PR, et al. Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report. Plos One. 8: e65636. PMID 23840348 DOI: 10.1371/Journal.Pone.0065636  0.6
2013 Dang TN, Dobson-Stone C, Glaros EN, Kim WS, Hallupp M, Bartley L, Piguet O, Hodges JR, Halliday GM, Double KL, Schofield PR, Crouch PJ, Kwok JB. Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model. Disease Models & Mechanisms. 6: 1198-204. PMID 23798570 DOI: 10.1242/Dmm.011460  0.3
2013 Xu M, Zou L, Wilde A, Meiser B, Barlow-Stewart K, Chan B, Mitchell PB, Sousa MS, Schofield PR. Exploring culture-specific differences in beliefs about causes, kinship and the heritability of major depressive disorder: the views of Anglo-Celtic and Chinese-Australians. Journal of Genetic Counseling. 22: 613-24. PMID 23681279 DOI: 10.1007/S10897-013-9593-3  0.329
2013 Dobson-Stone C, Luty AA, Thompson EM, Blumbergs P, Brooks WS, Short CL, Field CD, Panegyres PK, Hecker J, Solski JA, Blair IP, Fullerton JM, Halliday GM, Schofield PR, Kwok JB. Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: genetic, clinical and neuropathological analysis. Acta Neuropathologica. 125: 523-33. PMID 23338750 DOI: 10.1007/S00401-013-1078-9  0.595
2013 Hsu SC, Sears RL, Lemos RR, Quintáns B, Huang A, Spiteri E, Nevarez L, Mamah C, Zatz M, Pierce KD, Fullerton JM, Adair JC, Berner JE, Bower M, Brodaty H, ... ... Schofield PR, et al. Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification. Neurogenetics. 14: 11-22. PMID 23334463 DOI: 10.1007/S10048-012-0349-2  0.607
2013 Kanchibhotla SC, Mather KA, Wen W, Schofield PR, Kwok JB, Sachdev PS. Genetics of ageing-related changes in brain white matter integrity - a review. Ageing Research Reviews. 12: 391-401. PMID 23128052 DOI: 10.1016/J.Arr.2012.10.003  0.324
2013 Wilde A, Mitchell PB, Meiser B, Schofield PR. Implications of the use of genetic tests in psychiatry, with a focus on major depressive disorder: a review. Depression and Anxiety. 30: 267-75. PMID 22987566 DOI: 10.1002/Da.22000  0.369
2013 Mitchell P, Roberts G, Fullerton JM, Green M, Breakspear M, Frankland A, Levy F, Lenroot R, Wen W, Lau P, Joslyn C, Schofield P. Imaging and genetic studies in youth at high risk for bipolar disorder Bipolar Disorders. 15: 41-41. DOI: 10.1111/Bdi.12080  0.618
2012 Porter MA, Dobson-Stone C, Kwok JB, Schofield PR, Beckett W, Tassabehji M. A role for transcription factor GTF2IRD2 in executive function in Williams-Beuren syndrome. Plos One. 7: e47457. PMID 23118870 DOI: 10.1371/Journal.Pone.0047457  0.32
2012 Li M, Wang Y, Zheng XB, Ikeda M, Iwata N, Luo XJ, Chong SA, Lee J, Rietschel M, Zhang F, Müller-Myhsok B, Cichon S, Weinberger DR, Mattheisen M, Schulze TG, ... ... Schofield PR, et al. Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility. Schizophrenia Research. 142: 200-5. PMID 23102693 DOI: 10.1016/J.Schres.2012.10.008  0.321
2012 Dobson-Stone C, Hallupp M, Bartley L, Shepherd CE, Halliday GM, Schofield PR, Hodges JR, Kwok JB. C9ORF72 repeat expansion in clinical and neuropathologic frontotemporal dementia cohorts. Neurology. 79: 995-1001. PMID 22875086 DOI: 10.1212/Wnl.0B013E3182684634  0.316
2012 Weickert CS, Tiwari Y, Schofield PR, Mowry BJ, Fullerton JM. Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity. Translational Psychiatry. 2: e104. PMID 22832904 DOI: 10.1038/Tp.2012.25  0.619
2012 Rahman B, Meiser B, Sachdev P, Barlow-Stewart K, Otlowski M, Zilliacus E, Schofield P. To know or not to know: An update of the literature on the psychological and behavioral impact of genetic testing for Alzheimer disease risk Genetic Testing and Molecular Biomarkers. 16: 935-942. PMID 22731638 DOI: 10.1089/Gtmb.2011.0300  0.328
2012 McAuley EZ, Scimone A, Tiwari Y, Agahi G, Mowry BJ, Holliday EG, Donald JA, Weickert CS, Mitchell PB, Schofield PR, Fullerton JM. Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26. Plos One. 7: e38172. PMID 22693595 DOI: 10.1371/Journal.Pone.0038172  0.653
2011 Wilde A, Bonfiglioli C, Meiser B, Mitchell PB, Schofield PR. Portrayal of psychiatric genetics in Australian print news media, 1996-2009. The Medical Journal of Australia. 195: 401-4. PMID 21978348 DOI: 10.5694/Mja10.10167  0.345
2011 Assareh A, Mather KA, Schofield PR, Kwok JB, Sachdev PS. The genetics of white matter lesions. Cns Neuroscience & Therapeutics. 17: 525-40. PMID 21951372 DOI: 10.1111/J.1755-5949.2010.00181.X  0.397
2011 Wilde A, Meiser B, Mitchell PB, Schofield PR. Community attitudes to genetic susceptibility-based mental health interventions for healthy people in a large national sample. Journal of Affective Disorders. 134: 280-7. PMID 21763000 DOI: 10.1016/J.Jad.2011.06.023  0.355
2011 Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, ... ... Schofield PR, et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. American Journal of Human Genetics. 88: 372-81. PMID 21353194 DOI: 10.1016/J.Ajhg.2011.01.017  0.375
2011 Wilde A, Meiser B, Mitchell PB, Hadzi-Pavlovic D, Schofield PR. Community interest in predictive genetic testing for susceptibility to major depressive disorder in a large national sample. Psychological Medicine. 41: 1605-13. PMID 21159212 DOI: 10.1017/S0033291710002394  0.314
2011 Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, ... ... Schofield PR, et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder (The American Journal of Human Genetics (2011) 88, (372-381)) American Journal of Human Genetics. 88: 396. DOI: 10.1016/J.Ajhg.2011.03.001  0.36
2010 Luty AA, Kwok JB, Dobson-Stone C, Loy CT, Coupland KG, Karlström H, Sobow T, Tchorzewska J, Maruszak A, Barcikowska M, Panegyres PK, Zekanowski C, Brooks WS, Williams KL, Blair IP, ... ... Schofield PR, et al. Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease. Annals of Neurology. 68: 639-49. PMID 21031579 DOI: 10.1002/Ana.22274  0.307
2010 Cederholm JM, Absalom NL, Sugiharto S, Griffith R, Schofield PR, Lewis TM. Conformational changes in extracellular loop 2 associated with signal transduction in the glycine receptor. Journal of Neurochemistry. 115: 1245-55. PMID 20874766 DOI: 10.1111/J.1471-4159.2010.07021.X  0.559
2010 Mitchell PB, Meiser B, Wilde A, Fullerton J, Donald J, Wilhelm K, Schofield PR. Predictive and diagnostic genetic testing in psychiatry. Clinics in Laboratory Medicine. 30: 829-46. PMID 20832655 DOI: 10.1016/J.Cll.2010.07.001  0.614
2010 Gatt JM, Nemeroff CB, Schofield PR, Paul RH, Clark CR, Gordon E, Williams LM. Early life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression. Biological Psychiatry. 68: 818-24. PMID 20728877 DOI: 10.1016/J.Biopsych.2010.06.025  0.302
2010 Fullerton JM, Tiwari Y, Agahi G, Heath A, Berk M, Mitchell PB, Schofield PR. Assessing oxidative pathway genes as risk factors for bipolar disorder. Bipolar Disorders. 12: 550-6. PMID 20712757 DOI: 10.1111/J.1399-5618.2010.00834.X  0.633
2010 Gatt JM, Williams LM, Schofield PR, Dobson-Stone C, Paul RH, Grieve SM, Clark CR, Gordon E, Nemeroff CB. Impact of the HTR3A gene with early life trauma on emotional brain networks and depressed mood. Depression and Anxiety. 27: 752-9. PMID 20694966 DOI: 10.1002/Da.20726  0.322
2010 Mitchell PB, Meiser B, Wilde A, Fullerton J, Donald J, Wilhelm K, Schofield PR. Predictive and diagnostic genetic testing in psychiatry. The Psychiatric Clinics of North America. 33: 225-43. PMID 20159347 DOI: 10.1016/J.Psc.2009.10.001  0.615
2010 Fullerton JM, Donald JA, Mitchell PB, Schofield PR. Two-dimensional genome scan identifies multiple genetic interactions in bipolar affective disorder. Biological Psychiatry. 67: 478-86. PMID 20022591 DOI: 10.1016/J.Biopsych.2009.10.022  0.618
2010 Wilde A, Meiser B, Mitchell PB, Schofield PR. Public interest in predictive genetic testing, including direct-to-consumer testing, for susceptibility to major depression: preliminary findings. European Journal of Human Genetics : Ejhg. 18: 47-51. PMID 19690586 DOI: 10.1038/Ejhg.2009.138  0.335
2010 Fullerton JM, Tiwari Y, Schofield PR, Weickert CS. INCREASED FREQUENCY OF NOVEL NRG1 GENE VARIANTS IN SCHIZOPHRENIA AND THE EFFECT OF NUCLEOTIDE VARIATION ON MRNA ISOFORM TRANSCRIPTIONAL REGULATION Schizophrenia Research. 117: 334-335. DOI: 10.1016/J.Schres.2010.02.576  0.574
2009 Wilde A, Meiser B, Mitchell PB, Schofield PR. Community attitudes towards mental health interventions for healthy people on the basis of genetic susceptibility. The Australian and New Zealand Journal of Psychiatry. 43: 1070-6. PMID 20001402 DOI: 10.3109/00048670903179152  0.331
2009 Sachdev PS, Lammel A, Trollor JN, Lee T, Wright MJ, Ames D, Wen W, Martin NG, Brodaty H, Schofield PR. A comprehensive neuropsychiatric study of elderly twins: the Older Australian Twins Study. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 12: 573-82. PMID 19943720 DOI: 10.1375/Twin.12.6.573  0.308
2009 McAuley EZ, Fullerton JM, Blair IP, Donald JA, Mitchell PB, Schofield PR. Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort. Psychiatric Genetics. 19: 244-52. PMID 19584773 DOI: 10.1097/Ypg.0B013E32832Ceea9  0.63
2009 Wilhelm K, Meiser B, Mitchell PB, Finch AW, Siegel JE, Parker G, Schofield PR. Issues concerning feedback about genetic testing and risk of depression. The British Journal of Psychiatry : the Journal of Mental Science. 194: 404-10. PMID 19407269 DOI: 10.1192/Bjp.Bp.107.047514  0.305
2009 Cederholm JM, Schofield PR, Lewis TM. Gating mechanisms in Cys-loop receptors. European Biophysics Journal : Ebj. 39: 37-49. PMID 19404635 DOI: 10.1007/S00249-009-0452-Y  0.548
2009 Absalom NL, Schofield PR, Lewis TM. Pore structure of the Cys-loop ligand-gated ion channels. Neurochemical Research. 34: 1805-15. PMID 19381804 DOI: 10.1007/S11064-009-9971-2  0.549
2009 Gatt JM, Nemeroff CB, Dobson-Stone C, Paul RH, Bryant RA, Schofield PR, Gordon E, Kemp AH, Williams LM. Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety. Molecular Psychiatry. 14: 681-95. PMID 19153574 DOI: 10.1038/Mp.2008.143  0.304
2009 McAuley EZ, Blair IP, Liu Z, Fullerton JM, Scimone A, Van Herten M, Evans MR, Kirkby KC, Donald JA, Mitchell PB, Schofield PR. A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26. Molecular Psychiatry. 14: 492-500. PMID 18227837 DOI: 10.1038/Sj.Mp.4002146  0.34
2008 Luty AA, Kwok JB, Thompson EM, Blumbergs P, Brooks WS, Loy CT, Dobson-Stone C, Panegyres PK, Hecker J, Nicholson GA, Halliday GM, Schofield PR. Pedigree with frontotemporal lobar degeneration--motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9. Bmc Neurology. 8: 32. PMID 18755042 DOI: 10.1186/1471-2377-8-32  0.364
2008 Sugiharto S, Lewis TM, Moorhouse AJ, Schofield PR, Barry PH. Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels. Biophysical Journal. 95: 4698-715. PMID 18708455 DOI: 10.1529/Biophysj.107.125690  0.539
2008 Fullerton JM, Liu Z, Badenhop RF, Scimone A, Blair IP, Van Herten M, Donald JA, Mitchell PB, Schofield PR. Genome screen of 15 Australian bipolar affective disorder pedigrees supports previously identified loci for bipolar susceptibility genes. Psychiatric Genetics. 18: 156-61. PMID 18628676 DOI: 10.1097/Ypg.0B013E3282Fa1861  0.631
2008 Meiser B, Kasparian NA, Mitchell PB, Strong K, Simpson JM, Tabassum L, Mireskandari S, Schofield PR. Attitudes to genetic testing in families with multiple cases of bipolar disorder. Genetic Testing. 12: 233-43. PMID 18554164 DOI: 10.1089/Gte.2007.0100  0.379
2008 Chetcuti A, Adams LJ, Mitchell PB, Schofield PR. Microarray gene expression profiling of mouse brain mRNA in a model of lithium treatment. Psychiatric Genetics. 18: 64-72. PMID 18349697 DOI: 10.1097/Ypg.0B013E3282Fb0051  0.311
2008 Chan DK, Mok V, Ng PW, Yeung J, Kwok JB, Fang ZM, Clarke R, Wong L, Schofield PR, Hattori N. PARK2 mutations and clinical features in a Chinese population with early-onset Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 115: 715-9. PMID 18188499 DOI: 10.1007/S00702-007-0011-6  0.303
2007 Karlstrom H, Kwok JB, Gregory GC, Hallupp M, Brooks WS, Schofield PR. No association of spastic paraparesis genes in PSEN1 Alzheimer's disease with spastic paraparesis. Neuroreport. 18: 1267-9. PMID 17632280 DOI: 10.1097/Wnr.0B013E3282405209  0.31
2007 Dobson-Stone C, Gatt JM, Kuan SA, Grieve SM, Gordon E, Williams LM, Schofield PR. Investigation of MCPH1 G37995C and ASPM A44871G polymorphisms and brain size in a healthy cohort. Neuroimage. 37: 394-400. PMID 17566767 DOI: 10.1016/J.Neuroimage.2007.05.011  0.311
2007 Meiser B, Mitchell PB, Kasparian NA, Strong K, Simpson JM, Mireskandari S, Tabassum L, Schofield PR. Attitudes towards childbearing, causal attributions for bipolar disorder and psychological distress: a study of families with multiple cases of bipolar disorder. Psychological Medicine. 37: 1601-11. PMID 17537283 DOI: 10.1017/S0033291707000852  0.372
2007 Gordon E, Liddell BJ, Brown KJ, Bryant R, Clark CR, DAS P, Dobson-Stone C, Falconer E, Felmingham K, Flynn G, Gatt JM, Harris A, Hermens DF, Hopkinson PJ, Kemp AH, ... ... Schofield P, et al. Integrating objective gene-brain-behavior markers of psychiatric disorders. Journal of Integrative Neuroscience. 6: 1-34. PMID 17472223 DOI: 10.1142/S0219635207001465  0.369
2006 Schofield PR, Blair IP, Chetcuti A, McAuley EZ, Fullerton JM, Donald JA, Mitchell PB. 03-04 Genetic and genomic approaches to better understanding bipolar disorder. Acta Neuropsychiatrica. 18: 321. PMID 27397362 DOI: 10.1017/S0924270800032038  0.347
2006 McAuley E, Blair I, Fullerton J, Donald J, Mitchell P, Schofield P. Identification of a bipolar disorder susceptibility locus on chromosome 15Q. Acta Neuropsychiatrica. 18: 261. PMID 27397211 DOI: 10.1017/S0924270800030544  0.303
2006 Fullerton J, Heath A, Mitchell P, Schofield P. Investigation of circadian disruption in bipolar disorder. Acta Neuropsychiatrica. 18: 251. PMID 27397185 DOI: 10.1017/S0924270800030283  0.322
2006 Hoth KF, Paul RH, Williams LM, Dobson-Stone C, Todd E, Schofield PR, Gunstad J, Cohen RA, Gordon E. Associations between the COMT Val/Met polymorphism, early life stress, and personality among healthy adults. Neuropsychiatric Disease and Treatment. 2: 219-25. PMID 19412467 DOI: 10.2147/Nedt.2006.2.2.219  0.317
2006 Gunstad J, Schofield P, Paul RH, Spitznagel MB, Cohen RA, Williams LM, Kohn M, Gordon E. BDNF Val66Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology. 53: 153-6. PMID 16707914 DOI: 10.1159/000093341  0.302
2006 Blair IP, Chetcuti AF, Badenhop RF, Scimone A, Moses MJ, Adams LJ, Craddock N, Green E, Kirov G, Owen MJ, Kwok JB, Donald JA, Mitchell PB, Schofield PR. Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele. Molecular Psychiatry. 11: 372-83. PMID 16402135 DOI: 10.1002/Ajmg.B.30233  0.374
2006 Chetcuti A, Adams LJ, Mitchell PB, Schofield PR. Altered gene expression in mice treated with the mood stabilizer sodium valproate. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 9: 267-76. PMID 15982445 DOI: 10.1017/S1461145705005717  0.329
2006 Gregory GC, Macdonald V, Schofield PR, Kril JJ, Halliday GM. Differences in regional brain atrophy in genetic forms of Alzheimer's disease. Neurobiology of Aging. 27: 387-93. PMID 15894410 DOI: 10.1016/J.Neurobiolaging.2005.03.011  0.31
2005 Blair IP, Badenhop RF, Scimone A, Moses MJ, Donald JA, Mitchell PB, Schofield PR. Identification, characterization, and association analysis of novel genes from the bipolar disorder susceptibility locus on chromosome 4q35. Psychiatric Genetics. 15: 199-204. PMID 16094255 DOI: 10.1097/00041444-200509000-00011  0.382
2005 Blair IP, Mitchell PB, Schofield PR. Techniques for the identification of genes involved in psychiatric disorders. The Australian and New Zealand Journal of Psychiatry. 39: 542-9. PMID 15996134 DOI: 10.1080/J.1440-1614.2005.01625.X  0.372
2005 Blair IP, Badenhop RF, Scimone A, Moses MJ, Kerr NP, Donald JA, Mitchell PB, Schofield PR. Association analysis of transcripts from the bipolar susceptibility locus on chromosome 4q35, exclusion of a pathogenic role for eight positional candidate genes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 134: 56-9. PMID 15717290 DOI: 10.1002/Ajmg.B.30131  0.373
2005 Meiser B, Mitchell PB, McGirr H, Van Herten M, Schofield PR. Implications of genetic risk information in families with a high density of bipolar disorder: an exploratory study. Social Science & Medicine (1982). 60: 109-18. PMID 15482871 DOI: 10.1016/J.Socscimed.2004.04.016  0.395
2004 Stanford PM, Brooks WS, Teber ET, Hallupp M, McLean C, Halliday GM, Martins RN, Kwok JB, Schofield PR. Frequency of tau mutations in familial and sporadic frontotemporal dementia and other tauopathies. Journal of Neurology. 251: 1098-104. PMID 15372253 DOI: 10.1007/S00415-004-0489-X  0.3
2004 Morris R, Morgan BS, Lewis TM, Pierce KD, Pisano A, Schofield PR. In vivo somatic delivery of plasmid DNA and retrograde transport to obtain cell-specific gene expression in the central nervous system. Journal of Neurochemistry. 90: 1445-52. PMID 15341528 DOI: 10.1111/J.1471-4159.2004.02612.X  0.55
2004 Absalom NL, Lewis TM, Schofield PR. Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure. Experimental Physiology. 89: 145-53. PMID 15123543 DOI: 10.1113/Expphysiol.2003.026815  0.549
2003 Mitchell PB, Schofield PR, Donald JA. Major leads in the search for susceptibility genes for depression. The Pharmacogenomics Journal. 3: 305-7. PMID 14610522 DOI: 10.1038/Sj.Tpj.6500212  0.312
2003 Absalom NL, Lewis TM, Kaplan W, Pierce KD, Schofield PR. Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor. The Journal of Biological Chemistry. 278: 50151-7. PMID 14525990 DOI: 10.1074/Jbc.M305357200  0.558
2003 Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI, Craddock N, DePaulo JR, Baron M, Gershon ES, Ekholm J, Cichon S, Turecki G, Claes S, Kelsoe JR, ... Schofield PR, et al. Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. American Journal of Human Genetics. 73: 49-62. PMID 12802785 DOI: 10.1086/376547  0.349
2003 Lewis TM, Schofield PR, McClellan AM. Kinetic determinants of agonist action at the recombinant human glycine receptor. The Journal of Physiology. 549: 361-74. PMID 12679369 DOI: 10.1113/Jphysiol.2002.037796  0.543
2003 Brooks WS, Kwok JB, Kril JJ, Broe GA, Blumbergs PC, Tannenberg AE, Lamont PJ, Hedges P, Schofield PR. Alzheimer's disease with spastic paraparesis and 'cotton wool' plaques: two pedigrees with PS-1 exon 9 deletions. Brain : a Journal of Neurology. 126: 783-91. PMID 12615638 DOI: 10.1093/Brain/Awg084  0.335
2003 Badenhop RF, Moses MJ, Scimone A, Adams LJ, Kwok JB, Jones AM, Davison G, Evans MR, Kirkby KC, Hewitt JE, Donald JA, Mitchell PB, Schofield PR. Genetic refinement and physical mapping of a 2.3 Mb probable disease region associated with a bipolar affective disorder susceptibility locus on chromosome 4q35. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 117: 23-32. PMID 12555231 DOI: 10.1002/Ajmg.B.10023  0.329
2002 Blair IP, Adams LJ, Badenhop RF, Moses MJ, Scimone A, Morris JA, Ma L, Austin CP, Donald JA, Mitchell PB, Schofield PR. A transcript map encompassing a susceptibility locus for bipolar affective disorder on chromosome 4q35. Molecular Psychiatry. 7: 867-73. PMID 12232780 DOI: 10.1038/Sj.Mp.4001113  0.373
2002 Badenhop RF, Moses MJ, Scimone A, Mitchell PB, Ewen-White KR, Rosso A, Donald JA, Adams LJ, Schofield PR. A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19. Molecular Psychiatry. 7: 594-603. PMID 12140782 DOI: 10.1038/Sj.Mp.4001025  0.319
2002 Rees MI, Lewis TM, Kwok JB, Mortier GR, Govaert P, Snell RG, Schofield PR, Owen MJ. Hyperekplexia associated with compound heterozygote mutations in the beta-subunit of the human inhibitory glycine receptor (GLRB). Human Molecular Genetics. 11: 853-60. PMID 11929858 DOI: 10.1093/Hmg/11.7.853  0.573
2002 Brodaty H, Mitchell P, Luscombe G, Kwok JJ, Badenhop RF, McKenzie R, Schofield PR. Familial idiopathic basal ganglia calcification (Fahr's disease) without neurological, cognitive and psychiatric symptoms is not linked to the IBGC1 locus on chromosome 14q. Human Genetics. 110: 8-14. PMID 11810290 DOI: 10.1007/S00439-001-0650-X  0.362
2001 Rees MI, Lewis TM, Vafa B, Ferrie C, Corry P, Muntoni F, Jungbluth H, Stephenson JB, Kerr M, Snell RG, Schofield PR, Owen MJ. Compound heterozygosity and nonsense mutations in the alpha(1)-subunit of the inhibitory glycine receptor in hyperekplexia. Human Genetics. 109: 267-70. PMID 11702206 DOI: 10.1007/S004390100569  0.572
2001 Badenhop RF, Moses MJ, Scimone A, Mitchell PB, Ewen KR, Rosso A, Donald JA, Adams LJ, Schofield PR. A genome screen of a large bipolar affective disorder pedigree supports evidence for a susceptibility locus on chromosome 13q. Molecular Psychiatry. 6: 396-403. PMID 11443523 DOI: 10.1038/Sj.Mp.4000887  0.358
2001 Badenhop RF, Cherian S, Lord RS, Baysal BE, Taschner PE, Schofield PR. Novel mutations in the SDHD gene in pedigrees with familial carotid body paraganglioma and sensorineural hearing loss. Genes, Chromosomes & Cancer. 31: 255-63. PMID 11391796 DOI: 10.1002/Gcc.1142  0.32
2001 Kwok JB, Raskin S, Morgan G, Antoniuk SA, Bruk I, Schofield PR. Mutations in the glycine receptor alpha1 subunit (GLRA1) gene in hereditary hyperekplexia pedigrees: evidence for non-penetrance of mutation Y279C. Journal of Medical Genetics. 38: E17. PMID 11389164 DOI: 10.1136/Jmg.38.6.E17  0.316
2001 Schofield PR. Genetics, an alternative way to discover, characterize and understand ion channels. Clinical and Experimental Pharmacology & Physiology. 28: 84-8. PMID 11153544 DOI: 10.1046/J.1440-1681.2001.03409.X  0.302
1999 Vafa B, Lewis TM, Cunningham AM, Jacques P, Lynch JW, Schofield PR. Identification of a new ligand binding domain in the alpha1 subunit of the inhibitory glycine receptor. Journal of Neurochemistry. 73: 2158-66. PMID 10537076  0.502
1999 Lewis TM, Schofield PR. Structure-function relationships of the human glycine receptor: insights from hyperekplexia mutations. Annals of the New York Academy of Sciences. 868: 681-4. PMID 10414353 DOI: 10.1111/J.1749-6632.1999.Tb11345.X  0.553
1999 Kennedy JL, Basile VS, Macciardi FM, Detera-Wadleigh S, Evans KL, Holmans PA, Hovatta I, Jackson AD, Liu J, McInnis MG, Murphy I, Schofield PR, Vorsanova SG, Wildenauer DB, Williams N. Chromosome 4 workshop summary: Sixth World Congress on Psychiatric Genetics, Bonn, Germany, October 6–10, 1998 American Journal of Medical Genetics. 88: 224-228. PMID 10374735 DOI: 10.1002/(Sici)1096-8628(19990618)88:3<224::Aid-Ajmg3>3.0.Co;2-J  0.342
1999 Kwok JB, Adams LJ, Salmon JA, Donald JA, Mitchell PB, Schofield PR. Nonparametric simulation-based statistical analyses for bipolar affective disorder locus on chromosome 21q22.3. American Journal of Medical Genetics. 88: 99-102. PMID 10050976 DOI: 10.1002/(Sici)1096-8628(19990205)88:1<99::Aid-Ajmg18>3.0.Co;2-9  0.321
1998 Adams LJ, Mitchell PB, Fielder SL, Rosso A, Donald JA, Schofield PR. A susceptibility locus for bipolar affective disorder on chromosome 4q35. American Journal of Human Genetics. 62: 1084-91. PMID 9545396 DOI: 10.1086/301826  0.328
1997 Donald JA, Salmon JA, Adams LJ, Littlejohn T, Maher A, Mitchell PB, Schofield PR. Parental sex effects in bipolar affective disorder pedigrees. Genetic Epidemiology. 14: 611-6. PMID 9433551 DOI: 10.1002/(Sici)1098-2272(1997)14:6<611::Aid-Gepi10>3.0.Co;2-T  0.329
1997 Baker M, Kwok JB, Kucera S, Crook R, Farrer M, Houlden H, Isaacs A, Lincoln S, Onstead L, Hardy J, Wittenberg L, Dodd P, Webb S, Hayward N, Tannenberg T, ... ... Schofield P, et al. Localization of frontotemporal dementia with parkinsonism in an Australian kindred to chromosome 17q21-22. Annals of Neurology. 42: 794-8. PMID 9392579 DOI: 10.1002/Ana.410420516  0.305
1997 Adams LJ, Salmon JA, Kwok JB, Vivero C, Donald JA, Mitchell PB, Schofield PR. Exclusion of linkage between bipolar affective disorder and chromosome 16 in 12 Australian pedigrees. American Journal of Medical Genetics. 74: 304-10. PMID 9184315 DOI: 10.1002/(Sici)1096-8628(19970531)74:3<304::Aid-Ajmg12>3.0.Co;2-S  0.332
1997 Kwok JB, Taddei K, Hallupp M, Fisher C, Brooks WS, Broe GA, Hardy J, Fulham MJ, Nicholson GA, Stell R, St George Hyslop PH, Fraser PE, Kakulas B, Clarnette R, Relkin N, ... ... Schofield PR, et al. Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype. Neuroreport. 8: 1537-42. PMID 9172170 DOI: 10.1097/00001756-199704140-00043  0.309
1996 Deckert J, Nöthen MM, Rietschel M, Wildenauer D, Bondy B, Ertl MA, Knapp M, Schofield PR, Albus M, Maier W, Propping P. Human adenosine A2a receptor (A2aAR) gene: systematic mutation screening in patients with schizophrenia. Journal of Neural Transmission (Vienna, Austria : 1996). 103: 1447-55. PMID 9029412 DOI: 10.1007/Bf01271259  0.344
1996 Adams LJ, Salmon J, Donald JA, Mitchell PB, Schofield PR. Nonlinkage of D6S260, a putative schizophrenia locus, to bipolar affective disorder. American Journal of Medical Genetics. 67: 485-7. PMID 8886167 DOI: 10.1002/(Sici)1096-8628(19960920)67:5<485::Aid-Ajmg9>3.0.Co;2-J  0.358
1996 Mitchell P, Adams L, Kwok J, Salmon J, Donald J, Rosso A, Schofield P. Linkage analyses of chromosomes 6 (pter-p22), 16, 18 (pericentromeric) and 21 (q22.3) in bipolar disorder pedigrees European Neuropsychopharmacology. 6: 184. DOI: 10.1016/0924-977X(96)88163-6  0.302
1995 Brooks WS, Martins RN, De Voecht J, Nicholson GA, Schofield PR, Kwok JB, Fisher C, Yeung LU, Van Broeckhoven C. A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. Neuroscience Letters. 199: 183-6. PMID 8577393 DOI: 10.1016/0304-3940(95)12046-7  0.306
1995 Rajendra S, Schofield PR. Molecular mechanisms of inherited startle syndromes. Trends in Neurosciences. 18: 80-2. PMID 7537418 DOI: 10.1016/0166-2236(95)80028-Z  0.315
1994 Ryan SG, Buckwalter MS, Lynch JW, Handford CA, Segura L, Shiang R, Wasmuth JJ, Camper SA, Schofield P, O'Connell P. A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouse. Nature Genetics. 7: 131-5. PMID 7920629 DOI: 10.1038/Ng0694-131  0.303
1994 Le F, Mitchell P, Vivero C, Waters B, Donald J, Selbie LA, Shine J, Schofield P. Exclusion of close linkage of bipolar disorder to the Gs-alpha subunit gene in nine Australian pedigrees. Journal of Affective Disorders. 32: 187-95. PMID 7531727 DOI: 10.1016/0165-0327(94)90017-5  0.314
Low-probability matches (unlikely to be authored by this person)
2002 Blair IP, Adam LJ, Badenhop RF, Moses MJ, Scimone A, Morris JA, Ma L, Austin CP, Donald JA, Mitchell PB, Schofield PR. Stylized transcript map of chromosome 4q35 encompassing the locus for a bipolar disorder susceptibility gene. Molecular Psychiatry. 7: 669. PMID 12192607 DOI: 10.1038/Sj.Mp.4001154  0.3
2001 Pierce KD, Handford CA, Morris R, Vafa B, Dennis JA, Healy PJ, Schofield PR. A nonsense mutation in the alpha1 subunit of the inhibitory glycine receptor associated with bovine myoclonus. Molecular and Cellular Neurosciences. 17: 354-63. PMID 11178872 DOI: 10.1006/Mcne.2000.0934  0.3
2009 Joffe RT, Gatt JM, Kemp AH, Grieve S, Dobson-Stone C, Kuan SA, Schofield PR, Gordon E, Williams LM. Brain derived neurotrophic factor Val66Met polymorphism, the five factor model of personality and hippocampal volume: Implications for depressive illness. Human Brain Mapping. 30: 1246-56. PMID 18548532 DOI: 10.1002/Hbm.20592  0.299
2009 Schofield PR, Kwok JB, Brooks WS, Loy CT. The genetics of familial dementias Pathology. 41: 30. DOI: 10.1097/01268031-200941001-00064  0.299
2008 Kwok JB, Loy CT, Hamilton G, Lau E, Hallupp M, Williams J, Owen MJ, Broe GA, Tang N, Lam L, Powell JF, Lovestone S, Schofield PR. Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Annals of Neurology. 64: 446-54. PMID 18991351 DOI: 10.1002/Ana.21476  0.299
2016 Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, ... ... Schofield PR, et al. Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). The Lancet. Neurology. PMID 27777020 DOI: 10.1016/S1474-4422(16)30229-0  0.298
2004 Badenhop RF, Jansen JC, Fagan PA, Lord RS, Wang ZG, Foster WJ, Schofield PR. The prevalence of SDHB, SDHC, and SDHD mutations in patients with head and neck paraganglioma and association of mutations with clinical features. Journal of Medical Genetics. 41: e99. PMID 15235042 DOI: 10.1136/Jmg.2003.011551  0.297
1997 Deckert J, Nöthen MM, Bryant SP, Schuffenhauer S, Schofield PR, Spurr NK, Propping P. Mapping of the human adenosine A2a receptor gene: relationship to potential schizophrenia loci on chromosome 22q and exclusion from the CATCH 22 region. Human Genetics. 99: 326-8. PMID 9050917 DOI: 10.1007/S004390050366  0.297
2007 Karl T, Duffy L, Scimone A, Harvey RP, Schofield PR. Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia. Genes, Brain, and Behavior. 6: 677-87. PMID 17309661 DOI: 10.1111/J.1601-183X.2006.00298.X  0.296
2015 Salminen LE, Schofield PR, Pierce KD, Zhao Y, Luo X, Wang Y, Laidlaw DH, Cabeen RP, Conturo TE, Tate DF, Akbudak E, Lane EM, Heaps JM, Bolzenius JD, Baker LM, et al. Neuromarkers of the common angiotensinogen polymorphism in healthy older adults: A comprehensive assessment of white matter integrity and cognition. Behavioural Brain Research. PMID 26318936 DOI: 10.1016/J.Bbr.2015.08.028  0.296
2013 Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, et al. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 81: 736-44. PMID 23884042 DOI: 10.1212/Wnl.0B013E3182A1Aafe  0.296
2000 Stanford PM, Halliday GM, Brooks WS, Kwok JB, Storey CE, Creasey H, Morris JG, Fulham MJ, Schofield PR. Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: expansion of the disease phenotype caused by tau gene mutations. Brain : a Journal of Neurology. 123: 880-93. PMID 10775534 DOI: 10.1093/Brain/123.5.880  0.296
2004 Brooks WS, Kwok JB, Halliday GM, Godbolt AK, Rossor MN, Creasey H, Jones AO, Schofield PR. Hemorrhage is uncommon in new Alzheimer family with Flemish amyloid precursor protein mutation. Neurology. 63: 1613-7. PMID 15534244 DOI: 10.1212/01.Wnl.0000142965.10778.C7  0.296
2007 Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, ... ... Schofield PR, et al. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. The Lancet. Neurology. 6: 857-68. PMID 17826340 DOI: 10.1016/S1474-4422(07)70221-1  0.295
2010 Bryant RA, Felmingham KL, Falconer EM, Pe Benito L, Dobson-Stone C, Pierce KD, Schofield PR. Preliminary evidence of the short allele of the serotonin transporter gene predicting poor response to cognitive behavior therapy in posttraumatic stress disorder. Biological Psychiatry. 67: 1217-9. PMID 20434135 DOI: 10.1016/J.Biopsych.2010.03.016  0.295
2020 Aschenbrenner AJ, James BD, McDade E, Wang G, Lim YY, Benzinger TLS, Cruchaga C, Goate A, Xiong C, Perrin R, Buckles V, Allegri R, Berman SB, Chhatwal JP, Fagan A, ... ... Schofield P, et al. Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 219-228. PMID 31914221 DOI: 10.1002/Alz.12010  0.294
2015 Salminen LE, Schofield PR, Pierce KD, Luo X, Zhao Y, Laidlaw DH, Cabeen RP, Conturo TE, Lane EM, Heaps JM, Bolzenius JD, Baker LM, Cooley SA, Scott S, Cagle LM, et al. Genetic markers of cholesterol transport and gray matter diffusion: a preliminary study of the CETP I405V polymorphism. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 26253899 DOI: 10.1007/S00702-015-1434-0  0.294
1998 Taddei K, Kwok JB, Kril JJ, Halliday GM, Creasey H, Hallupp M, Fisher C, Brooks WS, Chung C, Andrews C, Masters CL, Schofield PR, Martins RN. Two novel presenilin-1 mutations (Ser169Leu and Pro436Gln) associated with very early onset Alzheimer's disease. Neuroreport. 9: 3335-9. PMID 9831473 DOI: 10.1097/00001756-199810050-00034  0.294
2013 Bryant RA, Hung L, Dobson-Stone C, Schofield PR. The association between the oxytocin receptor gene (OXTR) and hypnotizability. Psychoneuroendocrinology. 38: 1979-84. PMID 23562248 DOI: 10.1016/J.Psyneuen.2013.03.002  0.293
2003 Kwok JB, Halliday GM, Brooks WS, Dolios G, Laudon H, Murayama O, Hallupp M, Badenhop RF, Vickers J, Wang R, Naslund J, Takashima A, Gandy SE, Schofield PR. Presenilin-1 mutation L271V results in altered exon 8 splicing and Alzheimer's disease with non-cored plaques and no neuritic dystrophy. The Journal of Biological Chemistry. 278: 6748-54. PMID 12493737 DOI: 10.1074/Jbc.M211827200  0.293
2004 Piguet O, Brooks WS, Halliday GM, Schofield PR, Stanford PM, Kwok JB, Spillantini MG, Yancopoulou D, Nestor PJ, Broe GA, Hodges JR. Similar early clinical presentations in familial and non-familial frontotemporal dementia. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1743-5. PMID 15548495 DOI: 10.1136/Jnnp.2003.031948  0.293
2012 Cash D, Ridgway G, Ryan N, Kinnunen K, Yeatman T, Malone I, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, Thompson P, Saykin A, Salloway S, ... ... Schofield P, et al. A voxel-based morphometry study of volumetric MRI in familial Alzheimer’s disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.052  0.293
1996 Tang MX, Maestre G, Tsai WY, Liu XH, Feng L, Chung WY, Chun M, Schofield P, Stern Y, Tycko B, Mayeux R. Effect of age, ethnicity, and head injury on the association between APOE genotypes and Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 6-15. PMID 8993479 DOI: 10.1111/J.1749-6632.1996.Tb32593.X  0.292
2013 Weickert CS, Fung SJ, Catts VS, Schofield PR, Allen KM, Moore LT, Newell KA, Pellen D, Huang XF, Catts SV, Weickert TW. Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia. Molecular Psychiatry. 18: 1185-92. PMID 23070074 DOI: 10.1038/Mp.2012.137  0.292
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/Scitranslmed.3007901  0.291
1997 Rajendra S, Lynch JW, Schofield PR. The glycine receptor. Pharmacology & Therapeutics. 73: 121-46. PMID 9131721 DOI: 10.1016/S0163-7258(96)00163-5  0.291
2000 Kwok JB, Smith MJ, Brooks WS, Kril J, Mclean C, Hallupp M, Schofield PR. Variable presentation of Alzheimer's disease and/or spastic paraparesis phenotypes in pedigrees with a novel PS-1 exon 9 gene deletion or exon 9 splice acceptor mutations Neurobiology of Aging. 21: 25. DOI: 10.1016/S0197-4580(00)82789-X  0.291
2014 Myers AJ, Williams L, Gatt JM, McAuley-Clark EZ, Dobson-Stone C, Schofield PR, Nemeroff CB. Variation in the oxytocin receptor gene is associated with increased risk for anxiety, stress and depression in individuals with a history of exposure to early life stress. Journal of Psychiatric Research. 59: 93-100. PMID 25262417 DOI: 10.1016/J.Jpsychires.2014.08.021  0.29
2013 Dobson-Stone C, Hallupp M, Loy CT, Thompson EM, Haan E, Sue CM, Panegyres PK, Razquin C, Seijo-Martínez M, Rene R, Gascon J, Campdelacreu J, Schmoll B, Volk AE, Brooks WS, ... Schofield PR, et al. C9ORF72 repeat expansion in Australian and Spanish frontotemporal dementia patients. Plos One. 8: e56899. PMID 23437264 DOI: 10.1371/Journal.Pone.0056899  0.289
2012 Kinnunen K, Cash D, Liang Y, Leung K, Cardoso M, Modat M, Malone I, Yeatman T, Nicholas J, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, ... ... Schofield P, et al. Cross-sectional cerebral volumetric differences and associations with estimated time to age-at-onset in familial Alzheimer's disease: Findings from the DIAN study Alzheimers & Dementia. 8: 23. DOI: 10.1016/J.Jalz.2012.05.064  0.289
2016 Kindler J, Weickert CS, Schofield PR, Lenroot R, Weickert TW. Raloxifene increases prefrontal activity during emotional inhibition in schizophrenia based on estrogen receptor genotype. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 27842943 DOI: 10.1016/J.Euroneuro.2016.10.009  0.288
2019 Mills L, Meiser B, Ahmad R, Schofield PR, Peate M, Levitan C, Trevena L, Barlow-Stewart K, Dobbins T, Christensen H, Sherman KA, Dunlop K, Mitchell PB. A cluster randomized controlled trial of an online psychoeducational intervention for people with a family history of depression. Bmc Psychiatry. 19: 29. PMID 30654777 DOI: 10.1186/S12888-018-1994-2  0.288
2006 Dobson-Stone C, Gatt JM, Kuan S, Paul RH, Gordon E, Williams LM, Schofield PR. 10-01 Understanding genotype-phenotype relationships using the Brain Resource International Database: Implications for psychiatric conditions. Acta Neuropsychiatrica. 18: 335-6. PMID 27397399 DOI: 10.1017/S0924270800032403  0.288
2012 Gatt JM, Korgaonkar MS, Schofield PR, Harris A, Clark CR, Oakley KL, Ram K, Michaelson H, Yap S, Stanners M, Wise V, Williams LM. The TWIN-E project in emotional wellbeing: study protocol and preliminary heritability results across four MRI and DTI measures. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 15: 419-41. PMID 22856376 DOI: 10.1017/Thg.2012.12  0.288
2016 Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Schofield PR, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1002/ana.24647  0.288
2008 Karlstrom H, Brooks WS, Kwok JB, Broe GA, Kril JJ, McCann H, Halliday GM, Schofield PR. Variable phenotype of Alzheimer's disease with spastic paraparesis. Journal of Neurochemistry. 104: 573-83. PMID 17995932 DOI: 10.1111/J.1471-4159.2007.05038.X  0.287
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Schofield PR, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/Journal.Pone.0152082  0.287
2012 Kinnunen K, Cash D, Leung K, Liang Y, Cardoso M, Modat M, Malone I, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, Thompson P, Saykin A, ... ... Schofield P, et al. Brain and hippocampal rates of atrophy in familial Alzheimer's disease mutation carriers: Preliminary findings from the DIAN study Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.172  0.287
1998 Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, Hackett J, Adamson J, Lincoln S, Dickson D, Davies P, ... ... Schofield PR, et al. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393: 702-5. PMID 9641683 DOI: 10.1038/31508  0.286
2001 Smith MJ, Kwok JB, McLean CA, Kril JJ, Broe GA, Nicholson GA, Cappai R, Hallupp M, Cotton RG, Masters CL, Schofield PR, Brooks WS. Variable phenotype of Alzheimer's disease with spastic paraparesis. Annals of Neurology. 49: 125-9. PMID 11198283 DOI: 10.1002/1531-8249(200101)49:1<125::Aid-Ana21>3.0.Co;2-1  0.286
2018 Lim YY, Hassenstab J, Goate A, Fagan AM, Benzinger TLS, Cruchaga C, McDade E, Chhatwal J, Levin J, Farlow MR, Graff-Radford NR, Laske C, Masters CL, Salloway S, Schofield P, et al. Effect of BDNFVal66Met on disease markers in dominantly inherited AD. Annals of Neurology. PMID 30014553 DOI: 10.1002/Ana.25299  0.286
2007 Hickie IB, Naismith SL, Ward PB, Scott EM, Mitchell PB, Schofield PR, Scimone A, Wilhelm K, Parker G. Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression. Journal of Affective Disorders. 98: 137-42. PMID 16930719 DOI: 10.1016/J.Jad.2006.07.010  0.285
2014 Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, ... ... Schofield PR, et al. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 83: 253-60. PMID 24928124 DOI: 10.1212/Wnl.0000000000000596  0.285
2020 Wong MW, Thalamuthu A, Braidy N, Mather KA, Liu Y, Ciobanu L, Baune BT, Armstrong NJ, Kwok J, Schofield P, Wright MJ, Ames D, Pickford R, Lee T, Poljak A, et al. Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins. Elife. 9. PMID 32697195 DOI: 10.7554/Elife.58954  0.285
2016 Lim YY, Hassenstab J, Cruchaga C, Goate A, Fagan AM, Benzinger TL, Maruff P, Snyder PJ, Masters CL, Allegri R, Chhatwal J, Farlow MR, Graff-Radford NR, Laske C, Levin J, ... ... Schofield PR, et al. BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 27521573 DOI: 10.1093/Brain/Aww200  0.285
2005 Kwok JB, Hallupp M, Loy CT, Chan DK, Woo J, Mellick GD, Buchanan DD, Silburn PA, Halliday GM, Schofield PR. GSK3B polymorphisms alter transcription and splicing in Parkinson's disease. Annals of Neurology. 58: 829-39. PMID 16315267 DOI: 10.1002/Ana.20691  0.285
2020 Castillo-Barnes D, Su L, Ramírez J, Salas-Gonzalez D, Martinez-Murcia FJ, Illan IA, Segovia F, Ortiz A, Cruchaga C, Farlow MR, Xiong C, Graff-Radford NR, Schofield PR, Masters CL, Salloway S, et al. Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning. An International Journal On Information Fusion. 58: 153-167. PMID 32284705 DOI: 10.1016/J.Inffus.2020.01.001  0.285
2019 Jia T, Chu C, Liu Y, van Dongen J, Papastergios E, Armstrong NJ, Bastin ME, Carrillo-Roa T, den Braber A, Harris M, Jansen R, Liu J, Luciano M, Ori APS, Roiz Santiañez R, ... ... Schofield PR, et al. Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group. Molecular Psychiatry. PMID 31811260 DOI: 10.1038/S41380-019-0605-Z  0.285
2019 Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, ... ... Schofield PR, et al. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30897203 DOI: 10.1093/Brain/Awz050  0.284
2018 Araque Caballero MÁ, Suárez-Calvet M, Duering M, Franzmeier N, Benzinger T, Fagan AM, Bateman RJ, Jack CR, Levin J, Dichgans M, Jucker M, Karch C, Masters CL, Morris JC, Weiner M, ... ... Schofield PR, et al. White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30239611 DOI: 10.1093/Brain/Awy229  0.283
2005 Panegyres PK, Kwok JB, Schofield PR, Blumbergs PC. A Western Australian kindred with Dutch cerebral amyloid angiopathy. Journal of the Neurological Sciences. 239: 75-80. PMID 16213528 DOI: 10.1016/J.Jns.2005.08.002  0.283
2010 Assareh A, Kwok JBJ, Mather KA, Piguet O, Broe GA, Schofield PR, Sachdev PS. SORL1 gene variants are associated with brain white matter hyperintensities and dementia Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.630  0.283
1983 Schofield PR, Djordjevic MA, Rolfe BG, Shine J, Watson JM. A molecular linkage map of nitrogenase and nodulation genes in Rhizobium trifolii Molecular Genetics and Genomics. 192: 459-465. DOI: 10.1007/Bf00392191  0.283
2016 Shiner CT, Pierce KD, Thompson-Butel AG, Trinh T, Schofield PR, McNulty PA. BDNF Genotype Interacts with Motor Function to Influence Rehabilitation Responsiveness Poststroke. Frontiers in Neurology. 7: 69. PMID 27242654 DOI: 10.3389/Fneur.2016.00069  0.282
2007 Wilhelm K, Siegel JE, Finch AW, Hadzi-Pavlovic D, Mitchell PB, Parker G, Schofield PR. The long and the short of it: associations between 5-HTT genotypes and coping with stress. Psychosomatic Medicine. 69: 614-20. PMID 17766691 DOI: 10.1097/Psy.0B013E31814Cec64  0.282
2010 Williams LM, Gatt JM, Grieve SM, Dobson-Stone C, Paul RH, Gordon E, Schofield PR. COMT Val(108/158)Met polymorphism effects on emotional brain function and negativity bias. Neuroimage. 53: 918-25. PMID 20139013 DOI: 10.1016/J.Neuroimage.2010.01.084  0.282
2013 Meiser B, Schofield PR, Trevena L, Wilde A, Barlow-Stewart K, Proudfoot J, Peate M, Dobbins T, Christensen H, Sherman KA, Karatas J, Mitchell PB. Cluster randomized controlled trial of a psycho-educational intervention for people with a family history of depression for use in general practice. Bmc Psychiatry. 13: 325. PMID 24289740 DOI: 10.1016/J.Euroneuro.2017.08.111  0.281
2013 Spronk DB, Veth CP, Arns M, Schofield PR, Dobson-Stone C, Ramaekers JG, Franke B, de Bruijn ER, Verkes RJ. DBH -1021C>T and COMT Val108/158Met genotype are not associated with the P300 ERP in an auditory oddball task. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 124: 909-15. PMID 23261162 DOI: 10.1016/J.Clinph.2012.11.008  0.281
2000 Schofield PR. Comment: the epidemiology of the genetic liability for schizophrenia Australian and New Zealand Journal of Psychiatry. 34. DOI: 10.1046/J.1440-1614.2000.00776.X  0.281
2008 Duncan CE, Chetcuti AF, Schofield PR. Coregulation of genes in the mouse brain following treatment with clozapine, haloperidol, or olanzapine implicates altered potassium channel subunit expression in the mechanism of antipsychotic drug action. Psychiatric Genetics. 18: 226-39. PMID 18797397 DOI: 10.1097/Ypg.0B013E3283053019  0.28
2008 Gatt JM, Kuan SA, Dobson-Stone C, Paul RH, Joffe RT, Kemp AH, Gordon E, Schofield PR, Williams LM. Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity. Biological Psychology. 79: 275-84. PMID 18721847 DOI: 10.1016/J.Biopsycho.2008.07.004  0.28
2017 Cairns M, Zhao X, Schofield P. Functional Characterisation of Mirna Implicated in Psychiatric Syndromes European Neuropsychopharmacology. 27: 496-497. DOI: 10.1016/J.Euroneuro.2016.09.593  0.279
2009 Schofield PR, Williams LM, Paul RH, Gatt JM, Brown K, Luty A, Cooper N, Grieve S, Dobson-Stone C, Morris C, Kuan SA, Gordon E. Disturbances in selective information processing associated with the BDNF Val66Met polymorphism: evidence from cognition, the P300 and fronto-hippocampal systems. Biological Psychology. 80: 176-88. PMID 18838100 DOI: 10.1016/J.Biopsycho.2008.09.001  0.279
1996 Tang M, Maestre G, Tsai W, Liu X, Feng L, Chung W, Chun M, Schofield PR, Stern Y, Tycko B, Mayeux RP. Relative Risk of Alzheimer Disease and Age-at-Onset Distributions, Based on APOE Genotypes among Elderly African Americans, Caucasians, and Hispanics in New York City American Journal of Human Genetics. 58: 574-584. DOI: 10.7916/D80V9R96  0.279
2006 Wilhelm K, Mitchell PB, Niven H, Finch A, Wedgwood L, Scimone A, Blair IP, Parker G, Schofield PR. Life events, first depression onset and the serotonin transporter gene. The British Journal of Psychiatry : the Journal of Mental Science. 188: 210-5. PMID 16507960 DOI: 10.1192/Bjp.Bp.105.009522  0.279
2014 Salminen LE, Schofield PR, Pierce KD, Lane EM, Heaps JM, Bolzenius JD, Baker LM, Luo X, Paul RH. Triallelic relationships between the serotonin transporter polymorphism and cognition among healthy older adults. The International Journal of Neuroscience. 124: 331-8. PMID 24044728 DOI: 10.3109/00207454.2013.845822  0.279
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, ... ... Schofield PR, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/Nejmoa1202753  0.279
1995 Rajendra S, Lynch JW, Pierce KD, French CR, Barry PH, Schofield PR. Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists. Neuron. 14: 169-75. PMID 7826634 DOI: 10.1016/0896-6273(95)90251-1  0.279
2006 Luty AA, Kwok JB, Thompson E, Blumbergs PC, Brooks W, Schofield PR. P1-318: A novel Alzheimer's disease locus associated with atypical ‘plaque-predominant’ neuropathology Alzheimer's & Dementia. 2: S190-S190. DOI: 10.1016/J.Jalz.2006.05.696  0.278
2017 Zwarte Sd, Brouwer R, Hillegers M, Cahn W, Pol HH, Kahn R, Alpert K, Wang L, Bramon E, Kane F, Murray R, Hajek T, Alda M, Roberts G, Mitchell P, ... Schofield P, et al. 278. ENIGMA-Relatives – Brain Volumes in First-Degree Relatives of Schizophrenia and Bipolar Patients Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.292  0.278
2019 Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, ... ... Schofield PR, et al. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. PMID 30651383 DOI: 10.1212/Wnl.0000000000006851  0.278
2019 Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Schofield PR, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/S41380-019-0404-6  0.278
2006 Pickering-Brown SM, Baker M, Gass J, Boeve BF, Loy CT, Brooks WS, Mackenzie IR, Martins RN, Kwok JB, Halliday GM, Kril J, Schofield PR, Mann DM, Hutton M. Mutations in progranulin explain atypical phenotypes with variants in MAPT. Brain : a Journal of Neurology. 129: 3124-6. PMID 17071927 DOI: 10.1093/Brain/Awl289  0.278
2013 Kinnunen K, Ryan N, Cash D, Leite AB, Finnegan S, Cardoso M, Leung K, Modat M, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Ringman J, Ghetti B, ... ... Schofield P, et al. Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene-dependent? Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.017  0.277
2008 Duffy L, Cappas E, Scimone A, Schofield PR, Karl T. Behavioral profile of a heterozygous mutant mouse model for EGF-like domain neuregulin 1. Behavioral Neuroscience. 122: 748-59. PMID 18729627 DOI: 10.1037/0735-7044.122.4.748  0.277
2019 Singh M, Jackson K, Wang JJ, Schofield P, Field M, Peters T, Luciani F, Gordon T, Goodnow C, Reed JH. 241 Single cell genomics of self-reactive B cells reveals the evolution from benign to pathogenic autoantibody and strategies for early diagnosis and personalised treatment Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.241  0.277
2011 Kwok J, Luty A, Dobson-Stone C, Loy C, Brooks W, Karlström H, Halliday G, Schofield P. P1-287: Positional cloning identifies SIGMAR1 gene as a causative locus for FTLD-MND in a large Australian pedigree Alzheimer's & Dementia. 7: S202-S202. DOI: 10.1016/J.Jalz.2011.05.568  0.277
2019 Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, et al. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease. Nature Medicine. PMID 30664784 DOI: 10.1038/S41591-018-0304-3  0.276
2020 Aschenbrenner AJ, Petros J, McDade E, Wang G, Balota DA, Benzinger TL, Cruchaga C, Goate A, Xiong C, Perrin R, Fagan AM, Graff-Radford N, Ghetti B, Levin J, Weidinger E, ... Schofield P, et al. Relationships between big-five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12038. PMID 32587883 DOI: 10.1002/Dad2.12038  0.276
2004 Kwok JB, Teber ET, Loy C, Hallupp M, Nicholson G, Mellick GD, Buchanan DD, Silburn PA, Schofield PR. Tau haplotypes regulate transcription and are associated with Parkinson's disease. Annals of Neurology. 55: 329-34. PMID 14991810 DOI: 10.1002/Ana.10826  0.276
2006 Gatt JM, Kuan S, Dobson-Stone C, Paul RH, Schofield PR, Gordon E, Williams LM. 10-05 Genotypes and neural binding in negative affect: the contribution of genetic polymorphisms to 40 Hz gamma phase synchrony. Acta Neuropsychiatrica. 18: 337-8. PMID 27397403 DOI: 10.1017/S0924270800032440  0.276
2018 Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Schofield PR, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/Brain/Awy008  0.276
2009 Williams LM, Gatt JM, Kuan SA, Dobson-Stone C, Palmer DM, Paul RH, Song L, Costa PT, Schofield PR, Gordon E. A polymorphism of the MAOA gene is associated with emotional brain markers and personality traits on an antisocial index. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1797-809. PMID 19194374 DOI: 10.1038/Npp.2009.1  0.276
2013 Salminen LE, Schofield PR, Lane EM, Heaps JM, Pierce KD, Cabeen R, Laidlaw DH, Akbudak E, Conturo TE, Correia S, Paul RH. Neuronal fiber bundle lengths in healthy adult carriers of the ApoE4 allele: a quantitative tractography DTI study. Brain Imaging and Behavior. 7: 274-81. PMID 23475756 DOI: 10.1007/S11682-013-9225-4  0.276
2009 Williams LM, Gatt JM, Schofield PR, Olivieri G, Peduto A, Gordon E. 'Negativity bias' in risk for depression and anxiety: brain-body fear circuitry correlates, 5-HTT-LPR and early life stress. Neuroimage. 47: 804-14. PMID 19446647 DOI: 10.1016/J.Neuroimage.2009.05.009  0.275
2002 Münch G, Shepherd CE, McCann H, Brooks WS, Kwok JB, Arendt T, Hallupp M, Schofield PR, Martins RN, Halliday GM. Intraneuronal advanced glycation endproducts in presenilin-1 Alzheimer's disease. Neuroreport. 13: 601-4. PMID 11973454 DOI: 10.1097/00001756-200204160-00013  0.275
1996 Le F, Townsend-Nicholson A, Baker E, Sutherland GR, Schofield PR. Characterization and chromosomal localization of the human A2a adenosine receptor gene: ADORA2A. Biochemical and Biophysical Research Communications. 223: 461-7. PMID 8670304 DOI: 10.1006/Bbrc.1996.0916  0.274
2007 Boucher AA, Arnold JC, Duffy L, Schofield PR, Micheau J, Karl T. Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol. Psychopharmacology. 192: 325-36. PMID 17333138 DOI: 10.1007/S00213-007-0721-3  0.274
2008 Williams LM, Gatt JM, Hatch A, Palmer DM, Nagy M, Rennie C, Cooper NJ, Morris C, Grieve S, Dobson-Stone C, Schofield P, Clark CR, Gordon E, Arns M, Paul RH. The integrate model of emotion, thinking and self regulation: an application to the "paradox of aging". Journal of Integrative Neuroscience. 7: 367-404. PMID 18988298 DOI: 10.1142/S0219635208001939  0.274
2018 Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Schofield PR, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/Journal.Pone.0195838  0.274
2017 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Dietzsch J, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Graff-Radford NR, Levin J, Galasko D, et al. Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease. Scientific Reports. 7: 1225. PMID 28450713 DOI: 10.1038/S41598-017-01327-W  0.273
2012 Wilhelm K, Gillis I, Reddy J, Mitchell PB, Campbell L, Dobson-Stone C, Pierce KD, Schofield PR. Association between serotonin transporter promoter polymorphisms and psychological distress in a diabetic population. Psychiatry Research. 200: 343-8. PMID 22921508 DOI: 10.1016/J.Psychres.2012.07.008  0.273
2007 Alexander DM, Williams LM, Gatt JM, Dobson-Stone C, Kuan SA, Todd EG, Schofield PR, Cooper NJ, Gordon E. The contribution of apolipoprotein E alleles on cognitive performance and dynamic neural activity over six decades. Biological Psychology. 75: 229-38. PMID 17433528 DOI: 10.1016/J.Biopsycho.2007.03.001  0.272
2012 Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, ... ... Schofield PR, et al. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation. 2: 975-984. PMID 23139856 DOI: 10.4155/Cli.12.93  0.272
2018 Gordon BA, Blazey TM, Su Y, Hari-Raj A, Dincer A, Flores S, Christensen J, McDade E, Wang G, Xiong C, Cairns NJ, Hassenstab J, Marcus DS, Fagan AM, Jack CR, ... ... Schofield PR, et al. Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study. The Lancet. Neurology. PMID 29397305 DOI: 10.1016/S1474-4422(18)30028-0  0.271
2017 Ashworth M, Schofield P, Das-Munshi J. Physical health in severe mental illness British Journal of General Practice. 67: 436-437. PMID 28963399 DOI: 10.3399/Bjgp17X692621  0.271
2016 Schofield P, Das-Munshi J, Bécares L, Morgan C, Bhavsar V, Hotopf M, Hatch SL. Minority status and mental distress: a comparison of group density effects. Psychological Medicine. 1-9. PMID 27523979 DOI: 10.1017/S0033291716001835  0.271
1998 Vafa B, Schofield PR. Heritable mutations in the glycine, GABAA, and nicotinic acetylcholine receptors provide new insights into the ligand-gated ion channel receptor superfamily. International Review of Neurobiology. 42: 285-332. PMID 9476176 DOI: 10.1016/S0074-7742(08)60613-3  0.27
2004 Brooks WS, Kwok JB, Halliday GM, Godbolt AK, Rossor MN, Creasey HM, Jones AO, Schofield PR. P4-087 Familial Alzheimer's disease and cerebral haemorrhage: a second family with the flemish APP ALA692GLY mutation Neurobiology of Aging. 25: S499. DOI: 10.1016/S0197-4580(04)81645-2  0.27
2016 Routledge KM, Burton KL, Williams LM, Harris A, Schofield PR, Clark CR, Gatt JM. Shared versus distinct genetic contributions of mental wellbeing with depression and anxiety symptoms in healthy twins. Psychiatry Research. 244: 65-70. PMID 27472172 DOI: 10.1016/J.Psychres.2016.07.016  0.27
2015 Brautigam H, Moreno CL, Steele JW, Bogush A, Dickstein DL, Kwok JB, Schofield PR, Thinakaran G, Mathews PM, Hof PR, Gandy S, Ehrlich ME. Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1-/- phenotype and forms complexes with wildtype PS1 and nicastrin. Scientific Reports. 5: 17042. PMID 26608390 DOI: 10.1038/Srep17042  0.27
2016 Routledge KM, Burton KL, Williams LM, Harris A, Schofield PR, Clark CR, Gatt JM. The shared and unique genetic relationship between mental well-being, depression and anxiety symptoms and cognitive function in healthy twins. Cognition & Emotion. 1-15. PMID 27690266 DOI: 10.1080/02699931.2016.1232242  0.269
2013 Felmingham KL, Dobson-Stone C, Schofield PR, Quirk GJ, Bryant RA. The brain-derived neurotrophic factor Val66Met polymorphism predicts response to exposure therapy in posttraumatic stress disorder. Biological Psychiatry. 73: 1059-63. PMID 23312562 DOI: 10.1016/J.Biopsych.2012.10.033  0.269
2020 Shin J, Ma S, Hofer E, Patel Y, Vosberg DE, Tilley S, Roshchupkin GV, Sousa AMM, Jian X, Gottesman R, Mosley TH, Fornage M, Saba Y, Pirpamer L, Schmidt R, ... ... Schofield PR, et al. Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cerebral Cortex (New York, N.Y. : 1991). PMID 32198502 DOI: 10.1093/Cercor/Bhaa035  0.269
2018 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Fox NN, Graff-Radford NR, Levin J, Danek A, et al. Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30266303 DOI: 10.1016/J.Jalz.2018.06.3059  0.268
2006 Teber ET, Crawford E, Bolton KB, Van Dyk D, Schofield PR, Kapoor V, Church WB. Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration. Bmc Bioinformatics. 7: 33. PMID 16426464 DOI: 10.1186/1471-2105-7-33  0.268
2003 Stanford PM, Shepherd CE, Halliday GM, Brooks WS, Schofield PW, Brodaty H, Martins RN, Kwok JB, Schofield PR. Mutations in the tau gene that cause an increase in three repeat tau and frontotemporal dementia. Brain : a Journal of Neurology. 126: 814-26. PMID 12615641 DOI: 10.1093/Brain/Awg090  0.268
2007 Gatt JM, Clark CR, Kemp AH, Liddell BJ, Dobson-Stone C, Kuan SA, Schofield PR, Williams LM. A genotype-endophenotype-phenotype path model of depressed mood: integrating cognitive and emotional markers. Journal of Integrative Neuroscience. 6: 75-104. PMID 17472225 DOI: 10.1142/S0219635207001398  0.268
2015 Weickert TW, Weinberg D, Lenroot R, Catts SV, Wells R, Vercammen A, O'Donnell M, Galletly C, Liu D, Balzan R, Short B, Pellen D, Curtis J, Carr VJ, Kulkarni J, ... Schofield PR, et al. Adjunctive raloxifene treatment improves attention and memory in men and women with schizophrenia. Molecular Psychiatry. 20: 685-94. PMID 25980345 DOI: 10.1038/Mp.2015.11  0.267
1997 Atkinson MR, Townsend-Nicholson A, Nicholl JK, Sutherland GR, Schofield PR. Cloning, characterisation and chromosomal assignment of the human adenosine A3 receptor (ADORA3) gene. Neuroscience Research. 29: 73-9. PMID 9293494 DOI: 10.1016/S0168-0102(97)00073-4  0.267
2018 Bakre AT, Chen R, Khutan R, Wei L, Smith T, Qin G, Danat IM, Zhou W, Schofield P, Clifford A, Wang J, Verma A, Zhang C, Ni J. Association between fish consumption and risk of dementia: a new study from China and a systematic literature review and meta-analysis. Public Health Nutrition. 1-12. PMID 29551101 DOI: 10.1017/S136898001800037X  0.267
2019 Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, ... ... Schofield PW, ... ... Schofield PR, et al. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. 10: 2068. PMID 31043617 DOI: 10.1038/S41467-019-10160-W  0.267
2009 Dobson-Stone C, Hallupp M, Schofield PR, Kwok JB. P4-304: SIGMAR1 Association Analysis With Dementia And Parkinsonism Phenotypes Alzheimer's & Dementia. 5: e19-e19. DOI: 10.1016/J.Jalz.2009.07.083  0.267
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, ... ... Schofield PR, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/Pnas.1317918110  0.266
2014 Woodhead C, Ashworth M, Schofield P, Henderson M. Patterns of physical co-/multi-morbidity among patients with serious mental illness: a London borough-based cross-sectional study Bmc Family Practice. 15: 117-117. PMID 24919453 DOI: 10.1186/1471-2296-15-117  0.266
1990 Schofield PR, Shivers BD, Seeburg PH. The role of receptor subtype diversity in the CNS. Trends in Neurosciences. 13: 8-11. PMID 1688675 DOI: 10.1016/0166-2236(90)90052-C  0.265
1995 Lynch JW, Rajendra S, Barry PH, Schofield PR. Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator. The Journal of Biological Chemistry. 270: 13799-806. PMID 7775436 DOI: 10.1074/Jbc.270.23.13799  0.265
2011 Schofield P, Ashworth M, Jones R. Ethnic isolation and psychosis: re-examining the ethnic density effect Psychological Medicine. 41: 1263-1269. PMID 20860862 DOI: 10.1017/S0033291710001649  0.265
1987 Braun T, Schofield PR, Shivers BD, Pritchett DB, Seeburg PH. A novel subtype of muscarinic receptor identified by homology screening. Biochemical and Biophysical Research Communications. 149: 125-32. PMID 3120722 DOI: 10.1016/0006-291X(87)91613-5  0.263
2005 Jansen J, Taschner P, Schofield P, Fagan P, van der Mey A. Clinical Importance of Paraganglioma Genetics Skull Base. 15. DOI: 10.1055/S-2005-916588  0.262
2005 Halliday GM, Song YJ, Lepar G, Brooks WS, Kwok JB, Kersaitis C, Gregory G, Shepherd CE, Rahimi F, Schofield PR, Kril JJ. Pick bodies in a family with presenilin-1 Alzheimer's disease. Annals of Neurology. 57: 139-43. PMID 15622541 DOI: 10.1002/Ana.20366  0.262
2015 Ringman JM, Liang LJ, Zhou Y, Vangala S, Teng E, Kremen S, Wharton D, Goate A, Marcus DS, Farlow M, Ghetti B, McDade E, Masters CL, Mayeux RP, Rossor M, ... ... Schofield PR, et al. Erratum: Early behavioural changes in familial Alzheimers disease in the Dominantly Inherited Alzheimer Network (Brain (2015) 138 (103645) (10.1093/brain/awv004)) Brain. 138. PMID 26598496 DOI: 10.1093/Brain/Awv210  0.262
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, ... ... Schofield PR, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/Brain/Awy053  0.261
1989 Buckle VJ, Fujita N, Ryder-Cook AS, Derry JM, Barnard PJ, Lebo RV, Schofield PR, Seeburg PH, Bateson AN, Darlison MG. Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease. Neuron. 3: 647-54. PMID 2561974 DOI: 10.1016/0896-6273(89)90275-4  0.261
2006 Graham BA, Schofield PR, Sah P, Margrie TW, Callister RJ. Distinct physiological mechanisms underlie altered glycinergic synaptic transmission in the murine mutants spastic, spasmodic, and oscillator. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4880-90. PMID 16672662 DOI: 10.1523/Jneurosci.3991-05.2006  0.261
1994 Bishop LA, Robertson DM, Cahir N, Schofield PR. Specific roles for the asparagine-linked carbohydrate residues of recombinant human follicle stimulating hormone in receptor binding and signal transduction. Molecular Endocrinology (Baltimore, Md.). 8: 722-31. PMID 7935488 DOI: 10.1210/Mend.8.6.7935488  0.26
1999 Moorhouse AJ, Jacques P, Barry PH, Schofield PR. The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating. Molecular Pharmacology. 55: 386-95. PMID 9927632 DOI: 10.1124/Mol.55.2.386  0.26
2018 Zeraati M, Langley DB, Schofield P, Moye AL, Rouet R, Hughes WE, Bryan TM, Dinger ME, Christ D. I-motif DNA structures are formed in the nuclei of human cells. Nature Chemistry. PMID 29686376 DOI: 10.1038/S41557-018-0046-3  0.26
2013 Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Ances B, Sullivan C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, et al. IC-P-082: Disrupted functional connectivity in autosomal dominant Alzheimer's disease demonstrates network specificity and precedes brain volume loss: Findings from DIAN Alzheimer's & Dementia. 9: P49-P50. DOI: 10.1016/J.Jalz.2013.05.079  0.259
2000 Kwok JB, Li QX, Hallupp M, Whyte S, Ames D, Beyreuther K, Masters CL, Schofield PR. Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis. Annals of Neurology. 47: 249-53. PMID 10665499 DOI: 10.1002/1531-8249(200002)47:2<249::Aid-Ana18>3.0.Co;2-8  0.259
2015 Boraxbekk CJ, Ames D, Kochan NA, Lee T, Thalamuthu A, Wen W, Armstrong NJ, Kwok JB, Schofield PR, Reppermund S, Wright MJ, Trollor JN, Brodaty H, Sachdev P, Mather KA. Investigating the influence of KIBRA and CLSTN2 genetic polymorphisms on cross-sectional and longitudinal measures of memory performance and hippocampal volume in older individuals. Neuropsychologia. 78: 10-17. PMID 26415670 DOI: 10.1016/J.Neuropsychologia.2015.09.031  0.259
2014 Gatt JM, Burton KL, Schofield PR, Bryant RA, Williams LM. The heritability of mental health and wellbeing defined using COMPAS-W, a new composite measure of wellbeing. Psychiatry Research. 219: 204-13. PMID 24863866 DOI: 10.1016/J.Psychres.2014.04.033  0.258
2018 Routledge KM, Williams LM, Harris AWF, Schofield PR, Clark CR, Gatt JM. Genetic correlations between wellbeing, depression and anxiety symptoms and behavioral responses to the emotional faces task in healthy twins. Psychiatry Research. 264: 385-393. PMID 29677622 DOI: 10.1016/J.Psychres.2018.03.042  0.258
2018 McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, ... ... Schofield PR, et al. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. PMID 30217935 DOI: 10.1212/Wnl.0000000000006277  0.258
1992 Vandenberg RJ, French CR, Barry PH, Shine J, Schofield PR. Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site. Proceedings of the National Academy of Sciences of the United States of America. 89: 1765-9. PMID 1311851 DOI: 10.1073/Pnas.89.5.1765  0.258
2009 Duncan CE, Schofield PR, Weickert CS. K(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. Brain Research. 1304: 1-13. PMID 19781530 DOI: 10.1016/J.Brainres.2009.09.045  0.257
1996 Schofield PR, Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH. Molecular and genetic insights into ligand binding and signal transduction at the inhibitory glycine receptor. Cold Spring Harbor Symposia On Quantitative Biology. 61: 333-42. PMID 9246463 DOI: 10.1101/Sqb.1996.061.01.037  0.257
1988 Levitan ES, Schofield PR, Burt DR, Rhee LM, Wisden W, Köhler M, Fujita N, Rodriguez HF, Stephenson A, Darlison MG. Structural and functional basis for GABAA receptor heterogeneity. Nature. 335: 76-9. PMID 2842688 DOI: 10.1038/335076A0  0.256
2013 Cash D, Ridgway G, Modat M, Ryan N, Kinnunen K, Cardoso J, Benzinger T, Jack CR, Raichle M, Marcus D, Ringman J, Thompson P, Ghetti B, Salloway S, Sperling R, ... Schofield P, et al. Dissociating volume and intensity differences in familial Alzheimer's disease Alzheimers & Dementia. 9: 603. DOI: 10.1016/J.Jalz.2013.05.075  0.256
2004 Shepherd CE, Gregory GC, Vickers JC, Brooks WS, Kwok JB, Schofield PR, Kril JJ, Halliday GM. Positional effects of presenilin-1 mutations on tau phosphorylation in cortical plaques. Neurobiology of Disease. 15: 115-9. PMID 14751776 DOI: 10.1016/J.Nbd.2003.10.008  0.256
2000 Keramidas A, Moorhouse AJ, French CR, Schofield PR, Barry PH. M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective. Biophysical Journal. 79: 247-59. PMID 10866951 DOI: 10.1016/S0006-3495(00)76287-4  0.256
2006 Gatt JM, Kuan S, Dobson-Stone C, Paul RH, Schofield PR, Gordon E, Williams LM. 10-03 Identifying pathways to depressed mood and cognitive dysfunction: the BDNF Val66Met polymorphism and early life stress. Acta Neuropsychiatrica. 18: 336-7. PMID 27397401 DOI: 10.1017/S0924270800032427  0.255
2015 Burton KL, Williams LM, Richard Clark C, Harris A, Schofield PR, Gatt JM. Sex differences in the shared genetics of dimensions of self-reported depression and anxiety. Journal of Affective Disorders. 188: 35-42. PMID 26342886 DOI: 10.1016/J.Jad.2015.08.053  0.255
1986 Schofield PR, Watson JM. DNA sequence of Rhizobium trifolii nodulation genes reveals a reiterated and potentially regulatory sequence preceding nodABC and nodFE. Nucleic Acids Research. 14: 2891-903. PMID 3008100 DOI: 10.1093/Nar/14.7.2891  0.255
2012 Gatt J, Williams L, Schofield P, Clark R, Harris A. The TWIN-E project: identifying risk and resilience gene-brain markers of emotional well-being F1000research. 3. DOI: 10.7490/F1000Research.1090239.1  0.255
2017 Schofield PR, Thygesen M, Das-Munshi J, Becares L, Cantor-Graae E, Pedersen CB, Agerbo E. Ethnic density, urbanicity and psychosis risk for migrant groups - A population cohort study. Schizophrenia Research. 190: 82-87. PMID 28318842 DOI: 10.1016/J.Schres.2017.03.032  0.254
1990 Grenningloh G, Schmieden V, Schofield PR, Seeburg PH, Siddique T, Mohandas TK, Becker CM, Betz H. Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes. The Embo Journal. 9: 771-6. PMID 2155780 DOI: 10.1002/J.1460-2075.1990.Tb08172.X  0.254
1987 Schofield PR, Gibson AH, Dudman WF, Watson JM. Evidence for genetic exchange and recombination of Rhizobium symbiotic plasmids in a soil population. Applied and Environmental Microbiology. 53: 2942-7. PMID 16347509 DOI: 10.1128/Aem.53.12.2942-2947.1987  0.254
2018 Vöglein J, Noachtar S, McDade E, Quaid KA, Salloway S, Ghetti B, Noble J, Berman S, Chhatwal J, Mori H, Fox N, Allegri R, Masters CL, Buckles V, Ringman JM, ... ... Schofield PR, et al. Seizures as an early symptom of autosomal dominant Alzheimer's disease. Neurobiology of Aging. 76: 18-23. PMID 30616208 DOI: 10.1016/J.Neurobiolaging.2018.11.022  0.254
1997 Gready JE, Ranganathan S, Schofield PR, Matsuo Y, Nishikawa K. Predicted structure of the extracellular region of ligand-gated ion-channel receptors shows SH2-like and SH3-like domains forming the ligand-binding site. Protein Science : a Publication of the Protein Society. 6: 983-98. PMID 9144769 DOI: 10.1002/Pro.5560060504  0.253
2010 Pinto R, Ashworth M, Seed P, Rowlands G, Schofield P, Jones R. Differences in the primary care management of patients with psychosis from two ethnic groups: a population-based cross-sectional study Family Practice. 27: 439-446. PMID 20308245 DOI: 10.1093/Fampra/Cmq014  0.253
2013 Santarelli DM, Liu B, Duncan CE, Beveridge NJ, Tooney PA, Schofield PR, Cairns MJ. Gene-microRNA interactions associated with antipsychotic mechanisms and the metabolic side effects of olanzapine. Psychopharmacology. 227: 67-78. PMID 23318695 DOI: 10.1007/S00213-012-2939-Y  0.253
2020 Wong MW, Thalamuthu A, Braidy N, Mather KA, Liu Y, Ciobanu L, Baune BT, Armstrong NJ, Kwok J, Schofield P, Wright MJ, Ames D, Pickford R, Lee T, Poljak A, et al. Author response: Genetic and environmental determinants of variation in the plasma lipidome of older Australian twins Elife. DOI: 10.7554/Elife.58954.Sa2  0.253
2016 Woodhead C, Ashworth M, Broadbent M, Callard F, Hotopf M, Schofield P, Soncul M, Stewart RJ, Henderson MJ. Cardiovascular disease treatment among patients with severe mental illness: a data linkage study between primary and secondary care. The British Journal of General Practice : the Journal of the Royal College of General Practitioners. PMID 27114210 DOI: 10.3399/Bjgp16X685189  0.252
1987 Schofield PR, Darlison MG, Fujita N, Burt DR, Stephenson FA, Rodriguez H, Rhee LM, Ramachandran J, Reale V, Glencorse TA. Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family. Nature. 328: 221-7. PMID 3037384 DOI: 10.1038/328221A0  0.252
1995 Townsend-Nicholson A, Baker E, Schofield PR, Sutherland GR. Localization of the adenosine A1 receptor subtype gene (ADORA1) to chromosome 1q32.1. Genomics. 26: 423-5. PMID 7601478 DOI: 10.1016/0888-7543(95)80236-F  0.251
1995 Townsend-Nicholson A, Baker E, Sutherland GR, Schofield PR. Localization of the adenosine A2b receptor subtype gene (ADORA2B) to chromosome 17p11.2-p12 by FISH and PCR screening of somatic cell hybrids. Genomics. 25: 605-7. PMID 7790006 DOI: 10.1016/0888-7543(95)80074-V  0.251
2002 Kwok JB, Kapoor R, Gotoda T, Iwamoto Y, Iizuka Y, Yamada N, Isaacs KE, Kushwaha VV, Church WB, Schofield PR, Kapoor V. A missense mutation in kynurenine aminotransferase-1 in spontaneously hypertensive rats. The Journal of Biological Chemistry. 277: 35779-82. PMID 12145272 DOI: 10.1074/Jbc.C200303200  0.251
2014 Lawton R, Seed PT, Kordowicz M, Schofield P, Tylee A, Ashworth M. Using a patient-generated mental-health measure 'PSYCHLOPS' to explore problems in patients with coronary heart disease British Journal of General Practice. 64. PMID 24868073 DOI: 10.3399/Bjgp14X680137  0.25
2018 Kim WS, Fu Y, Dobson-Stone C, Hsiao JT, Shang K, Hallupp M, Schofield PR, Garner B, Karl T, Kwok JBJ. Effect of Fluvoxamine on Amyloid-β Peptide Generation and Memory. Journal of Alzheimer's Disease : Jad. 62: 1777-1787. PMID 29614681 DOI: 10.3233/Jad-171001  0.25
1988 Barnard EA, Darlison MG, Fujita N, Glencorse TA, Levitan ES, Reale V, Schofield PR, Seeburg PH, Squire MD, Stephenson FA. Molecular biology of the GABAA receptor. Advances in Experimental Medicine and Biology. 236: 31-45. PMID 2853566 DOI: 10.1007/978-1-4757-5971-6_3  0.25
2016 Schofield P, Das-Munshi J, Mathur R, Congdon P, Hull S. Does depression diagnosis and antidepressant prescribing vary by location? Analysis of ethnic density associations using a large primary-care dataset. Psychological Medicine. 46: 1321-9. PMID 26879871 DOI: 10.1017/S0033291715002913  0.25
2013 Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Ances B, Sullivan C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, et al. O4-03-03: Disrupted functional connectivity in autosomal dominant Alzheimer's disease demonstrates network specificity and precedes brain volume loss: Findings from the Dominantly Inherited Alzheimer Network Alzheimer's & Dementia. 9: P684-P685. DOI: 10.1016/J.Jalz.2013.04.348  0.249
2011 Assareh A, Mather K, Armstrong N, Kwok J, Wen W, Brodaty H, Schofield P, Sachdev P. Genome-wide association study of white matter lesions in older individuals Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.080  0.249
2020 Barthélemy NR, Li Y, Joseph-Mathurin N, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Perrin RJ, Goate AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC, ... ... Schofield PR, et al. A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease. Nature Medicine. 26: 398-407. PMID 32161412 DOI: 10.1038/S41591-020-0781-Z  0.249
2012 Wu MJ, Giersch T, McKay S, Schofield P, Skylas DJ, Cornish G, Hegedus E, Chin J. A novel hardness-related and starch granule-associated protein marker in wheat: LMW-GS-‘S’ Journal of Cereal Science. 55: 153-159. DOI: 10.1016/J.Jcs.2011.10.012  0.249
2006 Kwok JB, Hallupp M, Loy CT, Harold DH, Williams J, Owen MJ, Lovestone S, Powell J, Broe GA, Schofield PR. P1-332: Glycogen synthase kinase -3 beta polymorphisms interact with Tau haplotypes in Alzheimer's disease Alzheimer's & Dementia. 2: S194-S195. DOI: 10.1016/J.Jalz.2006.05.710  0.249
2011 Assareh A, Mather K, Wen W, Anstey K, Easteal SE, Tan X, Mack H, Kwok J, Schofield P, Sachdev P. P1-208: Association of PON2 Ser311Cys Polymorphism with Brain White Matter Lesions Alzheimer's & Dementia. 7: S177-S178. DOI: 10.1016/J.Jalz.2011.05.487  0.249
2017 McDade E, Wang G, Benzinger TL, Buckles VD, Fagan AM, Gordon BA, Hassenstab J, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier KL, Xiong C, Ricardo A, ... ... Schofield PR, et al. LONGITUDINAL BIOMARKER CHANGES IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE FROM THE DIAN STUDY Alzheimer's & Dementia. 13: P879-P880. DOI: 10.1016/J.Jalz.2017.07.265  0.249
2012 Benzinger T, Blazey T, Ances B, Raichle M, Ances B, Snyder A, Su Y, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... ... Schofield P, et al. IC-P-128: Progressive white matter abnormalities in autosomal dominant Alzheimer's disease: Results of the DIAN study Alzheimer's & Dementia. 8: P68-P69. DOI: 10.1016/j.jalz.2012.05.1858  0.249
2004 Verdile G, Groth D, Mathews PM, St George-Hyslop P, Fraser PE, Ramabhadran TV, Kwok JB, Schofield PR, Carter T, Gandy S, Martins RN. Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells. Molecular Psychiatry. 9: 594-602. PMID 14993906 DOI: 10.1038/Sj.Mp.4001458  0.249
1990 Ymer S, Draguhn A, Wisden W, Werner P, Keinänen K, Schofield PR, Sprengel R, Pritchett DB, Seeburg PH. Structural and functional characterization of the gamma 1 subunit of GABAA/benzodiazepine receptors. The Embo Journal. 9: 3261-7. PMID 2170110 DOI: 10.1002/J.1460-2075.1990.Tb07525.X  0.249
2017 Rouet R, Langley DB, Schofield P, Christie M, Roome B, Porebski BT, Buckle AM, Clifton BE, Jackson CJ, Stock D, Christ D. Structural reconstruction of protein ancestry. Proceedings of the National Academy of Sciences of the United States of America. PMID 28356519 DOI: 10.1073/Pnas.1613477114  0.249
2017 Brown BM, Sohrabi HR, Taddei K, Gardener SL, Rainey-Smith SR, Peiffer JJ, Xiong C, Fagan AM, Benzinger T, Buckles V, Erickson KI, Clarnette R, Shah T, Masters CL, Weiner M, ... ... Schofield PR, et al. Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28501451 DOI: 10.1016/J.Jalz.2017.03.008  0.248
2019 Das-Munshi J, Schofield P, Bhavsar V, Chang CK, Dewey ME, Morgan C, Stewart R, Thornicroft G, Prince MJ. Ethnic density and other neighbourhood associations for mortality in severe mental illness: a retrospective cohort study with multi-level analysis from an urbanised and ethnically diverse location in the UK. The Lancet. Psychiatry. PMID 31097399 DOI: 10.1016/S2215-0366(19)30126-9  0.248
2002 Moorhouse AJ, Keramidas A, Zaykin A, Schofield PR, Barry PH. Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels. The Journal of General Physiology. 119: 411-25. PMID 11981021 DOI: 10.1085/Jgp.20028553  0.248
2015 Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, ... ... Schofield PR, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/Wnl.0000000000001903  0.248
1999 Callister RJ, Schofield PR, Sah P. Use of murine mutants to study glycine receptor function. Clinical and Experimental Pharmacology & Physiology. 26: 929-31. PMID 10561817 DOI: 10.1046/J.1440-1681.1999.03148.X  0.248
2012 Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, et al. O2-06-01: Disrupted functional connectivity in autosomal dominant Alzheimer's disease: Preliminary findings from the DIAN study Alzheimer's & Dementia. 8: P244-P245. DOI: 10.1016/J.Jalz.2012.05.654  0.248
2020 Franzmeier N, Koutsouleris N, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Duering M, Dichgans M, Levin J, Gordon BA, Lim YY, Masters CL, Rossor M, Fox NC, ... ... Schofield PR, et al. Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32043733 DOI: 10.1002/Alz.12032  0.248
2005 Bateman GA, Levi CR, Schofield P, Wang Y, Lovett EC. The pathophysiology of the aqueduct stroke volume in normal pressure hydrocephalus: can co-morbidity with other forms of dementia be excluded? Neuroradiology. 47: 741-748. PMID 16021440 DOI: 10.1007/S00234-005-1418-0  0.247
1989 Pritchett DB, Sontheimer H, Shivers BD, Ymer S, Kettenmann H, Schofield PR, Seeburg PH. Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature. 338: 582-5. PMID 2538761 DOI: 10.1038/338582A0  0.247
2020 Singh M, Jackson KJL, Wang JJ, Schofield P, Field MA, Koppstein D, Peters TJ, Burnett DL, Rizzetto S, Nevoltris D, Masle-Farquhar E, Faulks ML, Russell A, Gokal D, Hanioka A, et al. Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody. Cell. PMID 32059783 DOI: 10.1016/J.Cell.2020.01.029  0.247
2013 Mathur R, Pollara E, Hull S, Schofield P, Ashworth M, Robson J. Ethnicity and stroke risk in patients with atrial fibrillation Heart. 99: 1087-1092. PMID 23720487 DOI: 10.1136/Heartjnl-2013-303767  0.247
2012 Schofield P, Chen R, Crichton N. Methods for assessing cardiovascular disease risk in a UK black population Heart. 98: 1373-1377. PMID 22842990 DOI: 10.1136/Heartjnl-2012-302168  0.246
1995 Rajendra S, Vandenberg RJ, Pierce KD, Cunningham AM, French PW, Barry PH, Schofield PR. The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element. The Embo Journal. 14: 2987-98. PMID 7621814 DOI: 10.1002/J.1460-2075.1995.Tb07301.X  0.246
2011 Graham BA, Tadros MA, Schofield PR, Callister RJ. Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse. The Journal of Physiology. 589: 2459-74. PMID 21486794 DOI: 10.1113/Jphysiol.2011.206326  0.246
1993 Cerpa-Poljak A, Bishop LA, Hort YJ, Chin CK, DeKroon R, Mahler SM, Smith GM, Stuart MC, Schofield PR. Isoelectric charge of recombinant human follicle-stimulating hormone isoforms determines receptor affinity and in vitro bioactivity. Endocrinology. 132: 351-6. PMID 8419133 DOI: 10.1210/Endo.132.1.8419133  0.246
1984 Scott DB, Court CB, Ronson CW, Scott KF, Watson JM, Schofield PR, Shine J. Organisation of nodulation and nitrogen fixation genes on a Rhizobium trifolii symbiotic plasmid Archives of Microbiology. 139: 151-157. DOI: 10.1007/Bf00401991  0.246
2017 Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway S, ... ... Schofield PR, et al. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28738187 DOI: 10.1016/J.Jalz.2017.06.2268  0.246
2012 Benzinger T, Blazey T, Koeppe R, Jack C, Raichle M, Su Y, Snyder A, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... ... Schofield P, et al. Elevated PiB precedes dementia in autosomal dominant Alzheimer's disease: PiB, FDG and atrophy in the DIAN cohort Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.132  0.245
1997 Lynch JW, Rajendra S, Pierce KD, Handford CA, Barry PH, Schofield PR. Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel. The Embo Journal. 16: 110-20. PMID 9009272 DOI: 10.1093/Emboj/16.1.110  0.245
2016 Gilkes A, Ashworth M, Schofield P, Harries TH, Durbaba S, Weston C, White P. Does COPD risk vary by ethnicity? A retrospective cross-sectional study. International Journal of Chronic Obstructive Pulmonary Disease. 11: 739-46. PMID 27103797 DOI: 10.2147/Copd.S96391  0.245
2015 Gilkes A, Schofield P, Ashworth M, Hull S, Durbaba S, White P. Cigarettes per day and ethnicity in London European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa1213  0.244
2006 Loy CT, Kwok JB, Blair IP, Hallupp M, Todd E, Schofield PR. P3-312: Functional consequences of tau haplotype and subhaplotypes in human brains Alzheimer's & Dementia. 2: S467-S467. DOI: 10.1016/J.Jalz.2006.05.1582  0.244
1989 Shivers BD, Killisch I, Sprengel R, Sontheimer H, Köhler M, Schofield PR, Seeburg PH. Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. Neuron. 3: 327-37. PMID 2561970 DOI: 10.1016/0896-6273(89)90257-2  0.244
2019 Tsai VW, Zhang HP, Manandhar R, Schofield P, Christ D, Lee-Ng KKM, Lebhar H, Marquis CP, Husaini Y, Brown DA, Breit SN. GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS. International Journal of Obesity (2005). PMID 31152154 DOI: 10.1038/S41366-019-0365-5  0.244
1998 Lynch JW, Jacques P, Pierce KD, Schofield PR. Zinc potentiation of the glycine receptor chloride channel is mediated by allosteric pathways. Journal of Neurochemistry. 71: 2159-68. PMID 9798943 DOI: 10.1046/J.1471-4159.1998.71052159.X  0.243
2020 Luo J, Agboola F, Grant E, Masters CL, Albert MS, Johnson SC, McDade EM, Vöglein J, Fagan AM, Benzinger T, Massoumzadeh P, Hassenstab J, Bateman RJ, Morris JC, Perrin RJ, ... ... Schofield PR, et al. Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study. Neurology. PMID 32873693 DOI: 10.1212/Wnl.0000000000010747  0.243
1996 Handford CA, Lynch JW, Baker E, Webb GC, Ford JH, Sutherland GR, Schofield PR. The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes. Brain Research. Molecular Brain Research. 35: 211-9. PMID 8717357 DOI: 10.1016/0169-328X(95)00218-H  0.243
2006 Duncan C, Chetcuti A, Schofield P. Coregulation of genes in the mouse brain following antipsychotic drug treatment. Acta Neuropsychiatrica. 18: 284-5. PMID 27397270 DOI: 10.1017/S0924270800031124  0.243
2015 Butt D, Chan TD, Bourne K, Hermes JR, Nguyen A, Statham A, O'Reilly LA, Strasser A, Price S, Schofield P, Christ D, Basten A, Ma CS, Tangye SG, Phan TG, et al. FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production. Immunity. 42: 890-902. PMID 25979420 DOI: 10.1016/J.Immuni.2015.04.010  0.243
2017 Schofield P, Das-Munshi J, Becares L, Agerbo E. Neighbourhood ethnic density and incidence of psychosis – First and second generation migrants compared European Psychiatry. 41. DOI: 10.1016/J.Eurpsy.2017.02.034  0.243
2004 Verdile G, Groth D, Mathews P, George-Hyslop PS, Fraser P, Ramabhadran T, Kwok J, Schofield P, Carter T, Gandy S, Martins R. P4-265 Baculoviral expressionof the presenilin mutation lacking exon 9 increase levels of an amyloid beta — like protein in SF9insect cells Neurobiology of Aging. 25: S550-S551. DOI: 10.1016/S0197-4580(04)81823-2  0.242
2018 Jiang J, Thalamuthu A, Ho JE, Mahajan A, Ek WE, Brown DA, Breit SN, Wang TJ, Gyllensten U, Chen MH, Enroth S, Januzzi JL, Lind L, Armstrong NJ, Kwok JB, ... Schofield PR, et al. A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood. Frontiers in Genetics. 9: 97. PMID 29628937 DOI: 10.3389/Fgene.2018.00097  0.242
2006 Alexander DM, Gatt JM, Kuan S, Dobson-Stone C, Todd EG, Schofield PR, Gordon E, Williams LM. 10-02 The neurodevelopmental effects of apolipoprotein E alleles on brain function. Acta Neuropsychiatrica. 18: 336. PMID 27397400 DOI: 10.1017/S0924270800032415  0.242
1998 STERN Y, TANG M, JACOBS DM, SANO M, MARDER K, BELL K, DOONEIEF G, SCHOFIELD P, CÔTÉ L. Prospective comparative study of the evolution of probable Alzheimer's disease and Parkinson's disease dementia Journal of the International Neuropsychological Society. 4: 279-284. DOI: 10.1017/S1355617798002793  0.242
2017 Hanseeuw BJ, McDade E, Schultz AP, Martins RN, Schofield PR, Masters CL, Graff-Radford NR, Salloway S, Danek A, Levin J, Buckles V, Goate AM, Benzinger TL, Morris JC, Bateman RJ, et al. GENOTYPIC VARIANCE MAY EXPLAIN THE BALANCE OF EARLY CORTICAL VERSUS STRIATAL AMYLOID DEPOSITION IN AUTOSOMAL DOMINANT AD Alzheimer's & Dementia. 13: P187-P188. DOI: 10.1016/J.Jalz.2017.07.043  0.241
2003 Lee DJ, Keramidas A, Moorhouse AJ, Schofield PR, Barry PH. The contribution of proline 250 (P-2') to pore diameter and ion selectivity in the human glycine receptor channel. Neuroscience Letters. 351: 196-200. PMID 14623139 DOI: 10.1016/J.Neulet.2003.08.005  0.241
1989 Sontheimer H, Becker CM, Pritchett DB, Schofield PR, Grenningloh G, Kettenmann H, Betz H, Seeburg PH. Functional chloride channels by mammalian cell expression of rat glycine receptor subunit. Neuron. 2: 1491-7. PMID 2483325 DOI: 10.1016/0896-6273(89)90195-5  0.241
2014 Fleetcroft R, Schofield P, Ashworth M. Variations in statin prescribing for primary cardiovascular disease prevention: cross-sectional analysis. Bmc Health Services Research. 14: 414-414. PMID 25240604 DOI: 10.1186/1472-6963-14-414  0.24
2006 Bateman GA, Levi CR, Schofield P, Wang Y, Lovett EC. Quantitative measurement of cerebral haemodynamics in early vascular dementia and Alzheimer's disease. Journal of Clinical Neuroscience. 13: 563-568. PMID 16540327 DOI: 10.1016/J.Jocn.2005.04.017  0.24
1988 Pritchett DB, Sontheimer H, Gorman CM, Kettenmann H, Seeburg PH, Schofield PR. Transient expression shows ligand gating and allosteric potentiation of GABAA receptor subunits. Science (New York, N.Y.). 242: 1306-8. PMID 2848320 DOI: 10.1126/Science.2848320  0.24
2016 McDade E, Weng H, Wang G, Xiong C, Fagan AM, Hassenstab J, Marcus DS, Morris JC, Benzinger TL, Cairns NJ, Goate AM, Buckles V, Holtzman DM, Berman S, Ghetti B, ... ... Schofield PR, et al. O5-02-01: Longitudinal Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease: The Dominantly Inherited Alzheimer Network Alzheimer's & Dementia. 12: P378-P379. DOI: 10.1016/J.Jalz.2016.06.710  0.24
2012 Mather K, Armstrong N, Assareh A, Kwok J, Crawford J, Reppermund S, Trollor J, Kochan N, Kang K, Slavin M, Draper B, Brodaty H, Schofield P, Sachdev P. Olfaction identification in older adults: A genome-wide association study Alzheimers & Dementia. 8: 671. DOI: 10.1016/J.Jalz.2012.05.1814  0.24
2013 Thomas J, Brier M, Bateman R, Snyder A, Benzinger T, Xiong C, Raichle M, Sperling R, Mayeux R, Ghetti B, Ringman J, Salloway S, McDade E, Rossor M, Schofield P, et al. IC-P-184: Resting state functional connectivity in autosomal dominant and sporadic Alzheimer's disease Alzheimer's & Dementia. 9: P105-P105. DOI: 10.1016/J.Jalz.2013.05.181  0.24
2016 Das-Munshi J, Ashworth M, Gaughran F, Hull S, Morgan C, Nazroo J, Roberts A, Rose D, Schofield P, Stewart R, Thornicroft G, Prince MJ. Ethnicity and cardiovascular health inequalities in people with severe mental illnesses: protocol for the E-CHASM study. Social Psychiatry and Psychiatric Epidemiology. PMID 26846127 DOI: 10.1007/S00127-016-1185-8  0.239
2002 Keramidas A, Moorhouse AJ, Pierce KD, Schofield PR, Barry PH. Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity. The Journal of General Physiology. 119: 393-410. PMID 11981020 DOI: 10.1085/Jgp.20028552  0.239
2017 Schofield PR, Thygesen M, Das-Munshi J, Becares L, Cantor-Graae E, Agerbo E, Pedersen CB. Neighbourhood ethnic density and psychosis — Is there a difference according to generation? Schizophrenia Research. 195: 501-505. PMID 28969931 DOI: 10.1016/J.Schres.2017.09.029  0.239
2015 Sarkar C, Dodhia H, Crompton J, Schofield P, White P, Millett C, Ashworth M. Hypertension: a cross-sectional study of the role of multimorbidity in blood pressure control. Bmc Family Practice. 16: 98. PMID 26248616 DOI: 10.1186/S12875-015-0313-Y  0.239
2003 Graham BA, Schofield PR, Sah P, Callister RJ. Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice. The Journal of Physiology. 551: 905-16. PMID 12837931 DOI: 10.1113/Jphysiol.2003.049064  0.239
2011 Dobson-Stone C, Luty A, Hallupp M, Coupland K, Brooks W, Panegyres P, Piguet O, Broe GA, Sobow T, Zekanowski C, Halliday G, Schofield P, Kwok J. Sigma non-opioid intracellular receptor 1 and neurodegeneration: prevalence of mutations and therapeutic implications Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.566  0.239
2011 Schofield P, Crosland A, Waheed W, Aseem S, Gask L, Wallace A, Dickens A, Tylee A. Patients' views of antidepressants: from first experiences to becoming expert. British Journal of General Practice. 61: 142-148. PMID 21439171 DOI: 10.3399/Bjgp11X567045  0.239
1999 Barry PH, Schofield PR, Moorhouse AJ. Glycine receptors: what gets in and why? Clinical and Experimental Pharmacology & Physiology. 26: 935-6. PMID 10561819 DOI: 10.1046/J.1440-1681.1999.03149.X  0.239
1987 Schofield PR, Rhee LM, Peralta EG. Primary structure of the human beta-adrenergic receptor gene. Nucleic Acids Research. 15: 3636. PMID 3033609 DOI: 10.1093/Nar/15.8.3636  0.238
2013 Blazey T, Jack C, Kantarci K, Preboske G, Ringman J, Brickman A, Raichle M, Hornbeck R, Saykin A, Salloway S, McDade E, Rossor M, Fox N, Thompson P, Correia S, ... ... Schofield P, et al. Prevalence and growth of cerebral microhemorrhages in autosomal dominant Alzheimer's disease Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.100  0.238
2006 Finch A, Baikie K, Mitchell P, Parker G, Reddy J, Schofield PR, Showyin T, Siegel J, Wedgwood L, Wilhelm K. Phenotypic correlates of the serotonin transporter gene. Acta Neuropsychiatrica. 18: 249. PMID 27397180 DOI: 10.1017/S0924270800030234  0.237
2005 Attia J, Schofield P. What now for Alzheimer's disease? An epidemiological evaluation of the AD2000 trial Australian Prescriber. 28: 134-135. DOI: 10.18773/Austprescr.2005.100  0.237
2001 Collie A, Maruff P, Shafiq-Antonacci R, Smith M, Hallup M, Schofield PR, Masters CL, Currie J. Memory decline in healthy older people: implications for identifying mild cognitive impairment. Neurology. 56: 1533-8. PMID 11402111 DOI: 10.1212/Wnl.56.11.1533  0.236
1995 Grossmann M, Szkudlinski MW, Tropea JE, Bishop LA, Thotakura NR, Schofield PR, Weintraub BD. Expression of human thyrotropin in cell lines with different glycosylation patterns combined with mutagenesis of specific glycosylation sites. Characterization of a novel role for the oligosaccharides in the in vitro and in vivo bioactivity. The Journal of Biological Chemistry. 270: 29378-85. PMID 7493973 DOI: 10.1074/Jbc.270.49.29378  0.236
2019 Ingram E, Jones R, Schofield P, Henderson C. Small area deprivation and stigmatising attitudes towards mental illness: a multilevel analysis of Health Survey for England (2014) data. Social Psychiatry and Psychiatric Epidemiology. PMID 31055630 DOI: 10.1007/S00127-019-01722-W  0.235
2012 Schofield P, Crichton N, Chen R. Correction: Methods for assessing cardiovascular disease risk in a UK black population Heart. 98: 1469-1469. DOI: 10.1136/Heartjnl-2012-302168Corr1  0.235
1989 Schofield PR, McFarland KC, Hayflick JS, Wilcox JN, Cho TM, Roy S, Lee NM, Loh HH, Seeburg PH. Molecular characterization of a new immunoglobulin superfamily protein with potential roles in opioid binding and cell contact. The Embo Journal. 8: 489-95. PMID 2721489 DOI: 10.1002/J.1460-2075.1989.Tb03402.X  0.235
2018 Das-Munshi J, Chang CK, Schofield P, Stewart R, Prince MJ. Depression and cause-specific mortality in an ethnically diverse cohort from the UK: 8-year prospective study. Psychological Medicine. 1-13. PMID 30180917 DOI: 10.1017/S0033291718002210  0.235
1995 Bishop LA, Nguyen TV, Schofield PR. Both of the beta-subunit carbohydrate residues of follicle-stimulating hormone determine the metabolic clearance rate and in vivo potency. Endocrinology. 136: 2635-40. PMID 7750487 DOI: 10.1210/Endo.136.6.7750487  0.235
2015 Ashworth M, White P, Jongsma H, Schofield P, Armstrong D. Antibiotic prescribing and patient satisfaction in primary care in England: cross-sectional analysis of national patient survey data and prescribing data. The British Journal of General Practice : the Journal of the Royal College of General Practitioners. PMID 26639947 DOI: 10.3399/Bjgp15X688105  0.234
2011 Walters P, Schofield P, Howard L, Ashworth M, Tylee A. The Relationship between Asthma and Depression in Primary Care Patients: A Historical Cohort and Nested Case Control Study Plos One. 6. PMID 21698276 DOI: 10.1371/Journal.Pone.0020750  0.234
1999 Lynch JW, Han NI, Schofield PR. Building new function into glycine receptors: a structural model for the activation of the glycine-gated chloride channel. Clinical and Experimental Pharmacology & Physiology. 26: 932-4. PMID 10561818 DOI: 10.1046/J.1440-1681.1999.03150.X  0.234
1989 Schofield PR, Pritchett DB, Sontheimer H, Kettenmann H, Seeburg PH. Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits. Febs Letters. 244: 361-4. PMID 2465923 DOI: 10.1016/0014-5793(89)80563-0  0.234
2013 Nasir L, Robert G, Fischer MD, Norman I, Murrells T, Schofield P. Facilitating knowledge exchange between health-care sectors, organisations and professions: A longitudinal mixed-methods study of boundary-spanning processes and their impact on health-care quality Health Services and Delivery Research. 1: 1-170. PMID 25642564 DOI: 10.3310/Hsdr01070  0.233
2007 Graham BA, Brichta AM, Schofield PR, Callister RJ. Altered potassium channel function in the superficial dorsal horn of the spastic mouse. The Journal of Physiology. 584: 121-36. PMID 17690143 DOI: 10.1113/Jphysiol.2007.138198  0.233
2013 Ashworth M, Schofield P, Doran T, Cookson R, Sutton M, Seed PT, Howe A, Fleetcroft R. The Public Health Impact score: a new measure of public health effectiveness for general practices in England. The British Journal of General Practice : the Journal of the Royal College of General Practitioners. 63: e291-9. PMID 23540486 DOI: 10.3399/Bjgp13X665260  0.233
1991 Braun T, Schofield PR, Sprengel R. Amino−terminal leucine−rich repeats in gonadotropin receptors determine hormone selectivity The Embo Journal. 10: 1885-1890. DOI: 10.1002/J.1460-2075.1991.Tb07714.X  0.233
2014 Swift J, Saing S, Rouet R, Dudgeon K, Schofield P, Sewell W, Christ D. Identification of aggregation inhibitors of the human antibody light chain repertoire by phage display. Protein Engineering, Design & Selection : Peds. 27: 405-9. PMID 25053818 DOI: 10.1093/Protein/Gzu026  0.233
1985 Watson JM, Schofield PR. Species-specific, symbiotic plasmid-located repeated DNA sequences in Rhizobium trifolii Molecular Genetics and Genomics. 199: 279-289. DOI: 10.1007/Bf00330270  0.233
2012 Dudgeon K, Rouet R, Kokmeijer I, Schofield P, Stolp J, Langley D, Stock D, Christ D. General strategy for the generation of human antibody variable domains with increased aggregation resistance Proceedings of the National Academy of Sciences of the United States of America. 109: 10879-10884. PMID 22745168 DOI: 10.1073/Pnas.1202866109  0.232
2016 Lee S, Zimmerman ME, Viqar F, Narkhede A, Tosto G, Lee Smith Benzinger T, Marcus DS, Goate AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, ... ... Schofield PR, et al. O2-03-02: are White Matter Hyperintensities a Core Feature of Alzheimer’s Disease or Just a Reflection of Amyloid Angiopathy? Evidence From the Dominantly Inherited Alzheimer Network (DIAN) Alzheimer's & Dementia. 12: P226-P226. DOI: 10.1016/J.Jalz.2016.06.406  0.232
2013 Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, ... ... Schofield PR, et al. Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial. Revue Neurologique. 169: 737-43. PMID 24016464 DOI: 10.1016/J.Neurol.2013.07.017  0.232
1985 Djordjevic MA, Schofield PR, Rolfe BG. Tn5 mutagenesis of Rhizobium trifolii host-specific nodulation genes result in mutants with altered host-range ability Molecular Genetics and Genomics. 200: 463-471. DOI: 10.1007/Bf00425732  0.231
2004 Gregory GC, Kwok JB, Xuereb J, Schofield PR, Halliday GM. P1-217 Beta amyloid toxicity in Alzheimer's disease Neurobiology of Aging. 25: S157-S158. DOI: 10.1016/S0197-4580(04)80530-X  0.231
2019 Kordowicz M, Czachowski S, Schofield P, Ashworth M. PSYCHLOPS in Polish primary care: how do clients conceptualise their problems on a patient-generated outcome measure? Heliyon. 5. PMID 31453395 DOI: 10.1016/J.Heliyon.2019.E02209  0.231
2009 Halliday GM, Warden L, Gregory G, Kwok J, Schofield P, Guillemin G, Shepherd C. Mass buildup of soluble oligomeric Aß40 occurs in sporadic Alzheimer's disease Alzheimers & Dementia. 5: 302. DOI: 10.1016/J.Jalz.2009.04.451  0.231
2012 Bateman R, Benzinger T, Cairns N, Fagan A, Goate A, Marcus D, Storandt M, Xiong C, Buckles V, Holtzman D, Moulder K, Oliver A, Santacruz A, Fox N, Ghetti B, ... ... Schofield P, et al. Presymptomatic Alzheimer's disease in the Dominantly Inherited Alzheimer's Network (DIAN) Alzheimers & Dementia. 8: 4. DOI: 10.1016/J.Jalz.2012.05.015  0.231
2012 Schofield P, Baawuah F, Seed PT, Ashworth M. Managing hypertension in general practice: a cross-sectional study of treatment and ethnicity. British Journal of General Practice. 62: 703-709. PMID 23265230 DOI: 10.3399/Bjgp12X656847  0.23
2020 Burnett DL, Schofield P, Langley DB, Jackson J, Bourne K, Wilson E, Porebski BT, Buckle AM, Brink R, Goodnow CC, Christ D. Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens. Proceedings of the National Academy of Sciences of the United States of America. PMID 32855302 DOI: 10.1073/Pnas.2005102117  0.23
1989 Ymer S, Schofield PR, Shivers BD, Pritchett DB, Lüddens H, Köhler M, Werner P, Sontheimer H, Kettenmann H, Seeburg PH. Molecular studies of the GABAA receptor. Journal of Protein Chemistry. 8: 352-5. PMID 2477011 DOI: 10.1007/Bf01674275  0.228
2012 Becker J, Koeppe R, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, Brickman A, Ghetti B, Masters C, et al. FDG metabolism in the DIAN study of autosomal dominant Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.655  0.228
2008 Loy CT, Brooks BS, Taddei K, Patton A, McLean C, Halliday GM, Martins R, Kwok JB, Schofield PR. 417: A consanguineous family with Frontotemporal Dementia/Motor Neuron Disease Journal of Clinical Neuroscience. 15: 347. DOI: 10.1016/J.Jocn.2007.07.030  0.228
1994 Baker E, Sutherland GR, Schofield PR. Localization of the glycine receptor alpha 1 subunit gene (GLRA1) to chromosome 5q32 by FISH. Genomics. 22: 491-3. PMID 7806244 DOI: 10.1006/Geno.1994.1419  0.228
2004 Wiggins RD, Schofield P, Sacker A, Head J, Bartley M. Social position and minor psychiatric morbidity over time in the British Household Panel Survey 1991–1998 Journal of Epidemiology and Community Health. 58: 779-787. PMID 15310805 DOI: 10.1136/Jech.2003.015958  0.228
2004 Keramidas A, Moorhouse AJ, Schofield PR, Barry PH. Ligand-gated ion channels: mechanisms underlying ion selectivity. Progress in Biophysics and Molecular Biology. 86: 161-204. PMID 15288758 DOI: 10.1016/J.Pbiomolbio.2003.09.002  0.228
2011 Schofield P, Saka O, Ashworth M. Ethnic differences in blood pressure monitoring and control in south east London British Journal of General Practice. 61: 190-196. PMID 21439177 DOI: 10.3399/Bjgp11X567126  0.227
1989 Ymer S, Draguhn A, Köhler M, Schofield PR, Seeburg PH. Sequence and expression of a novel GABAA receptor alpha subunit. Febs Letters. 258: 119-22. PMID 2556293 DOI: 10.1016/0014-5793(89)81630-8  0.227
1989 Ymer S, Schofield PR, Draguhn A, Werner P, Köhler M, Seeburg PH. GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs. The Embo Journal. 8: 1665-70. PMID 2548852 DOI: 10.1002/J.1460-2075.1989.Tb03557.X  0.227
1989 Schmieden V, Grenningloh G, Schofield PR, Betz H. Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor. The Embo Journal. 8: 695-700. DOI: 10.1002/J.1460-2075.1989.Tb03428.X  0.227
2014 Tadros MA, Farrell KE, Schofield PR, Brichta AM, Graham BA, Fuglevand AJ, Callister RJ. Intrinsic and synaptic homeostatic plasticity in motoneurons from mice with glycine receptor mutations. Journal of Neurophysiology. 111: 1487-98. PMID 24401707 DOI: 10.1152/Jn.00728.2013  0.227
2009 Wang KY, Seed P, Schofield P, Ibrahim S, Ashworth M. Which practices are high antibiotic prescribers? A cross-sectional analysis British Journal of General Practice. 59: 315-320. PMID 19843411 DOI: 10.3399/Bjgp09X472593  0.226
2019 Sønderby IE, Gústafsson Ó, Doan NT, Hibar DP, Martin-Brevet S, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn N, Blangero J, Boomsma DI, Bralten J, ... ... Schofield PR, et al. Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia. Molecular Psychiatry. PMID 30705424 DOI: 10.1038/S41380-019-0358-8  0.226
1998 Jacobs DM, Tang MX, Stern Y, Sano M, Marder K, Bell KL, Schofield P, Dooneief G, Gurland B, Mayeux R. Cognitive function in nondemented older women who took estrogen after menopause. Neurology. 50: 368-73. PMID 9484355 DOI: 10.1212/Wnl.50.2.368  0.226
1992 Vandenberg RJ, Handford CA, Schofield PR. Distinct agonist- and antagonist-binding sites on the glycine receptor. Neuron. 9: 491-6. PMID 1326295 DOI: 10.1016/0896-6273(92)90186-H  0.226
2015 Su Y, Blazey TM, Snyder AZ, Raichle ME, Marcus DS, Ances BM, Bateman RJ, Cairns NJ, Aldea P, Cash L, Christensen JJ, Friedrichsen K, Hornbeck RC, Farrar AM, Owen CJ, ... ... Schofield PR, et al. Partial volume correction in quantitative amyloid imaging. Neuroimage. 107: 55-64. PMID 25485714 DOI: 10.1016/J.Neuroimage.2014.11.058  0.226
2014 Sabouri Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters DK, Christ D, et al. Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity. Proceedings of the National Academy of Sciences of the United States of America. 111: E2567-75. PMID 24821781 DOI: 10.1073/Pnas.1406974111  0.226
2016 Das-Munshi J, Ashworth M, Dewey ME, Gaughran F, Hull S, Morgan C, Nazroo J, Petersen I, Schofield P, Stewart R, Thornicroft G, Prince MJ. Type 2 diabetes mellitus in people with severe mental illness: inequalities by ethnicity and age. Cross-sectional analysis of 588 408 records from the UK. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 27973692 DOI: 10.1111/Dme.13298  0.226
2019 Bhavsar V, Schofield P, Das-Munshi J, Henderson C. Regional differences in mental health stigma-Analysis of nationally representative data from the Health Survey for England, 2014. Plos One. 14: e0210834. PMID 30668597 DOI: 10.1371/Journal.Pone.0210834  0.226
1984 Schofield PR, Ridge RW, Rolfe BG, Shine J, Watson JM. Host-specific nodulation is encoded on a 14kb DNA fragment in Rhizobium trifolii. Plant Molecular Biology. 3: 3-11. PMID 24310254 DOI: 10.1007/Bf00023410  0.225
2017 Harries TH, Thornton H, Crichton S, Schofield P, Gilkes A, White PT. Hospital readmissions for COPD: a retrospective longitudinal study. Npj Primary Care Respiratory Medicine. 27: 31. PMID 28450741 DOI: 10.1038/S41533-017-0028-8  0.225
2014 Slasberg C, Watson N, Beresford P, Schofield P. Personalization of health care in England: have the wrong lessons been drawn from the personal health budget pilots? Journal of Health Services Research & Policy. 19: 183-188. PMID 24700211 DOI: 10.1177/1355819614527577  0.225
2009 Dennett AL, Schofield PR, Roake JE, Howes NK, Chin J. Starch swelling power and amylose content of triticale and Triticum timopheevii germplasm Journal of Cereal Science. 49: 393-397. DOI: 10.1016/J.Jcs.2009.01.005  0.225
2000 Oesterle SN, Sanborn TA, Ali N, Resar J, Ramee SR, Heuser R, Dean L, Knopf W, Schofield P, Schaer GL, Reeder G, Masden R, Yeung AC, Burkhoff D. Percutaneous transmyocardial laser revascularisation for severe angina: The PACIFIC randomised trial Lancet. 356: 1705-1710. PMID 11095257 DOI: 10.1016/S0140-6736(00)03203-7  0.224
2018 Burnett DL, Langley DB, Schofield P, Hermes JR, Chan TD, Jackson J, Bourne K, Reed JH, Patterson K, Porebski BT, Brink R, Christ D, Goodnow CC. Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination. Science (New York, N.Y.). 360: 223-226. PMID 29650674 DOI: 10.1126/Science.Aao3859  0.224
1985 Djordjevic MA, Schofield PR, Ridge RW, Morrison NA, Bassam BJ, Plazinski J, Watson JM, Rolfe BG. Rhizobium nodulation genes involved in root hair curling (Hac) are functionally conserved. Plant Molecular Biology. 4: 147-60. PMID 24310752 DOI: 10.1007/Bf02418762  0.224
1998 Dougherty C, Barucha J, Schofield PR, Jacobson KA, Liang BT. Cardiac myocytes rendered ischemia resistant by expressing the human adenosine A1 or A3 receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1785-92. PMID 9837869 DOI: 10.1096/Fasebj.12.15.1785  0.224
1985 Schofield PR, Watson JM. Conservation of nif- and species-specific domains within repeated promoter sequences from fast-growing Rhizobium species. Nucleic Acids Research. 13: 3407-18. PMID 3892479 DOI: 10.1093/Nar/13.10.3407  0.224
2001 Lynch JW, Han NL, Haddrill J, Pierce KD, Schofield PR. The surface accessibility of the glycine receptor M2-M3 loop is increased in the channel open state. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 2589-99. PMID 11306612 DOI: 10.1523/Jneurosci.21-08-02589.2001  0.224
2011 Czachowski S, Seed P, Schofield P, Ashworth M. Measuring psychological change during cognitive behaviour therapy in primary care: a Polish study using 'PSYCHLOPS' (Psychological Outcome Profiles). Plos One. 6. PMID 22194783 DOI: 10.1371/Journal.Pone.0027378  0.224
2018 Schofield P, Vazquez-Lombardi R, Abdelatti M, Nevoltris D, Goodnow CC, Christ D, Reed JH. Sequencing and Affinity Determination of Antigen-Specific B Lymphocytes from Peripheral Blood. Methods in Molecular Biology (Clifton, N.J.). 1827: 287-309. PMID 30196503 DOI: 10.1007/978-1-4939-8648-4_15  0.223
1989 Schofield PR. The GABAA receptor: molecular biology reveals a complex picture. Trends in Pharmacological Sciences. 10: 476-8. PMID 2559520 DOI: 10.1016/0165-6147(89)90041-2  0.223
2017 Vöglein J, Paumier KL, Jucker M, Preische O, Laske C, Xiong C, Schofield PR, Salloway S, Mori H, Cairns NJ, Morris JC, Bateman RJ, Danek A, Levin J. Motor Symptoms In Familial Alzheimer’S Disease: Frequency, Severity And Predictive Value Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1477  0.223
2017 Gilkes A, Hull S, Durbaba S, Schofield P, Ashworth M, Mathur R, White P. Ethnic differences in smoking intensity and COPD risk: an observational study in primary care. Npj Primary Care Respiratory Medicine. 27: 50. PMID 28871087 DOI: 10.1038/S41533-017-0052-8  0.223
2010 Mather KA, Assareh A, Kochan N, Crawford J, Kang K, Reppermund S, Trollor J, Kwok J, Draper B, Schofield P, Brodaty H, Sachdev P. APOE E4 carriers are associated with amnestic but not nonamnestic mild cognitive impairment in an elderly community sample Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1181  0.223
2019 Mazigi O, Schofield P, Langley DB, Christ D. Protein A superantigen: structure, engineering and molecular basis of antibody recognition. Protein Engineering Design & Selection. 32: 359-366. PMID 31641749 DOI: 10.1093/Protein/Gzz026  0.222
2011 O'Toole SA, Machalek DA, Shearer RF, Millar EK, Nair R, Schofield P, McLeod D, Cooper CL, McNeil CM, McFarland A, Nguyen A, Ormandy CJ, Qiu MR, Rabinovich B, Martelotto LG, et al. Hedgehog overexpression is associated with stromal interactions and predicts for poor outcome in breast cancer. Cancer Research. 71: 4002-14. PMID 21632555 DOI: 10.1158/0008-5472.Can-10-3738  0.222
2019 Schofield P, Kordowicz M, Pennycooke E, Armstrong D. Ethnic differences in psychosis-Lay epidemiology explanations. Health Expectations : An International Journal of Public Participation in Health Care and Health Policy. 22: 965-973. PMID 31037803 DOI: 10.1111/Hex.12901  0.222
2001 Herrera C, Casadó V, Ciruela F, Schofield P, Mallol J, Lluis C, Franco R. Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells. Molecular Pharmacology. 59: 127-134. DOI: 10.1124/Mol.59.1.127  0.222
2014 Harries TH, Seed PT, Jones S, Schofield P, White P. Chronic obstructive pulmonary disease hospital admissions and drugs--unexpected positive associations: a retrospective general practice cohort study. Npj Primary Care Respiratory Medicine. 24: 14006. PMID 24842126 DOI: 10.1038/Npjpcrm.2014.6  0.221
2018 Schofield P, Das-Munshi J. Big data: what it can and cannot achieve Bjpsych Advances. 24: 237-244. PMID 30079252 DOI: 10.1192/Bja.2018.15  0.221
2017 Schofield P. Big data in mental health research - do the ns justify the means? Using large data-sets of electronic health records for mental health research. Bjpsych Bulletin. 41: 129-132. PMID 28584647 DOI: 10.1192/Pb.Bp.116.055053  0.221
2012 Fleetcroft R, Schofield P, Duerden M, Ashworth M. Achievement of cholesterol targets and prescribing of higher-cost statins: a cross-sectional study in general practice British Journal of General Practice. 62: 815-820. PMID 23211261 DOI: 10.3399/Bjgp12X659286  0.22
1999 Akinci MK, Schofield PR. Widespread expression of GABA(A) receptor subunits in peripheral tissues. Neuroscience Research. 35: 145-53. PMID 10616918 DOI: 10.1016/S0168-0102(99)00078-4  0.22
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