Gareth B. Miles, Ph.D.. - Publications

Affiliations: 
University of St Andrews, Saint Andrews, Scotland, United Kingdom 
Area:
Spinal cord, electrophysiology, motoneuron, locomotion, ALS

50/63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sharples SA, Broadhead MJ, Gray JA, Miles GB. M-type potassium currents differentially affect activation of motoneuron subtypes and tune recruitment gain. The Journal of Physiology. PMID 37988235 DOI: 10.1113/JP285348  0.807
2023 Eleftheriadis PE, Pothakos K, Sharples SA, Apostolou PE, Mina M, Tetringa E, Tsape E, Miles GB, Zagoraiou L. Peptidergic modulation of motor neuron output via CART signaling at C bouton synapses. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300348120. PMID 37733738 DOI: 10.1073/pnas.2300348120  0.822
2023 Broadhead MJ, Ayvazian-Hancock A, Doucet K, Kantelberg O, Motherwell L, Zhu F, Grant SGN, Horrocks MH, Miles GB. Synaptic expression of TAR-DNA-binding protein 43 in the mouse spinal cord determined using super-resolution microscopy. Frontiers in Molecular Neuroscience. 16: 1027898. PMID 37671010 DOI: 10.3389/fnmol.2023.1027898  0.83
2022 Broadhead MJ, Bonthron C, Waddington J, Smith WV, Lopez MF, Burley S, Valli J, Zhu F, Komiyama NH, Smith C, Grant SGN, Miles GB. Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 35305541 DOI: 10.1007/s00401-022-02412-9  0.798
2021 Broadhead MJ, Bonthron C, Arcinas L, Bez S, Zhu F, Goff F, Nylk J, Dholakia K, Gunn-Moore F, Grant SGN, Miles GB. Author Correction: Nanostructural Diversity of Synapses in the Mammalian Spinal Cord. Scientific Reports. 11: 23160. PMID 34819586 DOI: 10.1038/s41598-021-02575-7  0.812
2021 Sharples SA, Miles GB. Maturation of persistent and hyperpolarization-activated inward currents shapes the differential activation of motoneuron subtypes during postnatal development. Elife. 10. PMID 34783651 DOI: 10.7554/eLife.71385  0.811
2021 Broadhead MJ, Miles GB. A Common Role for Astrocytes in Rhythmic Behaviours? Progress in Neurobiology. 102052. PMID 33894330 DOI: 10.1016/j.pneurobio.2021.102052  0.776
2020 Broadhead MJ, Bonthron C, Arcinas L, Bez S, Zhu F, Goff F, Nylk J, Dholakia K, Gunn-Moore F, Grant SGN, Miles GB. Nanostructural Diversity of Synapses in the Mammalian Spinal Cord. Scientific Reports. 10: 8189. PMID 32424125 DOI: 10.1038/S41598-020-64874-9  0.815
2020 Broadhead MJ, Miles GB. Bi-Directional Communication Between Neurons and Astrocytes Modulates Spinal Motor Circuits. Frontiers in Cellular Neuroscience. 14: 30. PMID 32180706 DOI: 10.3389/Fncel.2020.00030  0.843
2020 Nascimento F, Broadhead MJ, Tetringa E, Tsape E, Zagoraiou L, Miles G. Synaptic mechanisms underlying modulation of locomotor-related motoneuron output by premotor cholinergic interneurons. Elife. 9. PMID 32081133 DOI: 10.7554/Elife.54170  0.825
2019 Zhao C, Devlin AC, Chouhan AK, Selvaraj BT, Stavrou M, Burr K, Brivio V, He X, Mehta AR, Story D, Shaw CE, Dando O, Hardingham GE, Miles GB, Chandran S. Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology. Glia. PMID 31841614 DOI: 10.1002/Glia.23761  0.811
2019 Nascimento F, Spindler LRB, Miles GB. Balanced cholinergic modulation of spinal locomotor circuits via M2 and M3 muscarinic receptors. Scientific Reports. 9: 14051. PMID 31575899 DOI: 10.1038/S41598-019-50452-1  0.82
2019 Rozani I, Tsapara G, Witts EC, Deaville SJ, Miles GB, Zagoraiou L. Pitx2 cholinergic interneurons are the source of C bouton synapses on brainstem motor neurons. Scientific Reports. 9: 4936. PMID 30894556 DOI: 10.1038/S41598-019-39996-4  0.836
2019 Miles GB, Wyart C. Editorial overview: Motor control systems of the spinal cord and hindbrain Current Opinion in Physiology. 8: iii-v. DOI: 10.1016/J.Cophys.2019.04.003  0.477
2018 Acton D, Broadhead MJ, Miles GB. Modulation of spinal motor networks by astrocyte-derived adenosine is dependent on D1-like dopamine receptor signalling. Journal of Neurophysiology. PMID 29790837 DOI: 10.1152/Jn.00783.2017  0.839
2018 Selvaraj BT, Livesey MR, Zhao C, Gregory JM, James OT, Cleary EM, Chouhan AK, Gane AB, Perkins EM, Dando O, Lillico SG, Lee YB, Nishimura AL, Poreci U, Thankamony S, ... ... Miles GB, et al. C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity. Nature Communications. 9: 347. PMID 29367641 DOI: 10.1038/S41467-017-02729-0  0.809
2017 Acton D, Miles GB. Gliotransmission and adenosinergic modulation: insights from mammalian spinal motor networks. Journal of Neurophysiology. jn.00230.2017. PMID 28954893 DOI: 10.1152/Jn.00230.2017  0.75
2017 Acton D, Miles GB. Differential regulation of NMDA receptors by D-serine and glycine in mammalian spinal locomotor networks. Journal of Neurophysiology. jn.00810.2016. PMID 28202572 DOI: 10.1152/Jn.00810.2016  0.691
2017 Picton LD, Nascimento F, Broadhead MJ, Sillar KT, Miles GB. Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 906-921. PMID 28123025 DOI: 10.1523/Jneurosci.2005-16.2016  0.795
2017 Chouhan AK, Selvaraj BT, Gane A, Mehta AR, Burr K, Shaw CE, Chandran S, Miles GB. Functional maturity of motor neurons derived from control and ALS patient iPSCs is affected by human iPSC-derived astrocytes F1000research. 6. DOI: 10.7490/F1000Research.1115168.1  0.807
2016 Picton LD, Nascimento F, Broadhead MJ, Sillar KT, Miles GB. Sodium pumps mediate activity-dependent changes in mammalian motor networks. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27980114 DOI: 10.1523/JNEUROSCI.2005-16.2016  0.796
2016 Steude A, Witts EC, Miles GB, Gather MC. Arrays of microscopic organic LEDs for high-resolution optogenetics. Science Advances. 2: e1600061. PMID 27386540 DOI: 10.1126/Sciadv.1600061  0.765
2015 Witts EC, Nascimento F, Miles GB. Adenosine-mediated modulation of ventral horn interneurons and spinal motoneurons in neonatal mice. Journal of Neurophysiology. jn.00574.2014. PMID 26311185 DOI: 10.1152/Jn.00574.2014  0.823
2015 Acton D, Miles GB. Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine. Plos One. 10: e0134488. PMID 26252389 DOI: 10.1371/Journal.Pone.0134488  0.743
2015 Devlin AC, Burr K, Borooah S, Foster JD, Cleary EM, Geti I, Vallier L, Shaw CE, Chandran S, Miles GB. Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability. Nature Communications. 6: 5999. PMID 25580746 DOI: 10.1038/Ncomms6999  0.683
2014 Foster JD, Dunford C, Sillar KT, Miles GB. Nitric oxide-mediated modulation of the murine locomotor network. Journal of Neurophysiology. 111: 659-74. PMID 24259545 DOI: 10.1152/Jn.00378.2013  0.809
2014 Witts EC, Zagoraiou L, Miles GB. Anatomy and function of cholinergic C bouton inputs to motor neurons. Journal of Anatomy. 224: 52-60. PMID 23701140 DOI: 10.1111/Joa.12063  0.842
2014 Witts EC, Zagoraiou L, Miles GB. Corrigendum: Anatomy and function of cholinergic C bouton inputs to motor neurons. [J Anat (2013) 224, 52-60] DOI: 10.1111/joa.12063 Journal of Anatomy. 224: 528-528. DOI: 10.1111/joa.12158  0.813
2013 Antkowiak M, Torres-Mapa ML, Witts EC, Miles GB, Dholakia K, Gunn-Moore FJ. Fast targeted gene transfection and optogenetic modification of single neurons using femtosecond laser irradiation. Scientific Reports. 3: 3281. PMID 24257461 DOI: 10.1038/Srep03281  0.775
2012 Herron LR, Miles GB. Gender-specific perturbations in modulatory inputs to motoneurons in a mouse model of amyotrophic lateral sclerosis. Neuroscience. 226: 313-23. PMID 23000617 DOI: 10.1016/J.Neuroscience.2012.09.031  0.448
2012 Witts EC, Panetta KM, Miles GB. Glial-derived adenosine modulates spinal motor networks in mice. Journal of Neurophysiology. 107: 1925-34. PMID 22205649 DOI: 10.1152/Jn.00513.2011  0.83
2011 Miles GB, Sillar KT. Neuromodulation of vertebrate locomotor control networks. Physiology (Bethesda, Md.). 26: 393-411. PMID 22170958 DOI: 10.1152/Physiol.00013.2011  0.784
2011 Iwagaki N, Miles GB. Activation of group I metabotropic glutamate receptors modulates locomotor-related motoneuron output in mice. Journal of Neurophysiology. 105: 2108-20. PMID 21346211 DOI: 10.1152/Jn.01037.2010  0.584
2009 Zagoraiou L, Akay T, Martin JF, Brownstone RM, Jessell TM, Miles GB. A cluster of cholinergic premotor interneurons modulates mouse locomotor activity. Neuron. 64: 645-62. PMID 20005822 DOI: 10.1016/J.Neuron.2009.10.017  0.848
2008 Yohn DC, Miles GB, Rafuse VF, Brownstone RM. Transplanted mouse embryonic stem-cell-derived motoneurons form functional motor units and reduce muscle atrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12409-18. PMID 19020033 DOI: 10.1523/Jneurosci.1761-08.2008  0.764
2008 Mukhida K, Hong M, Miles GB, Phillips T, Baghbaderani BA, McLeod M, Kobayashi N, Sen A, Behie LA, Brownstone RM, Mendez I. A multitarget basal ganglia dopaminergic and GABAergic transplantation strategy enhances behavioural recovery in parkinsonian rats. Brain : a Journal of Neurology. 131: 2106-26. PMID 18669492 DOI: 10.1093/Brain/Awn149  0.754
2007 Miles GB, Hartley R, Todd AJ, Brownstone RM. Spinal cholinergic interneurons regulate the excitability of motoneurons during locomotion. Proceedings of the National Academy of Sciences of the United States of America. 104: 2448-53. PMID 17287343 DOI: 10.1073/Pnas.0611134104  0.837
2006 Ma L, Ostrovsky H, Miles G, Lipski J, Funk GD, Nicholson LF. Differential expression of group I metabotropic glutamate receptors in human motoneurons at low and high risk of degeneration in amyotrophic lateral sclerosis. Neuroscience. 143: 95-104. PMID 16979830 DOI: 10.1016/J.Neuroscience.2006.07.058  0.766
2006 Soundararajan P, Miles GB, Rubin LL, Brownstone RM, Rafuse VF. Motoneurons derived from embryonic stem cells express transcription factors and develop phenotypes characteristic of medial motor column neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3256-68. PMID 16554476 DOI: 10.1523/Jneurosci.5537-05.2006  0.782
2005 Miles GB, Dai Y, Brownstone RM. Mechanisms underlying the early phase of spike frequency adaptation in mouse spinal motoneurones. The Journal of Physiology. 566: 519-32. PMID 15878947 DOI: 10.1113/Jphysiol.2005.086033  0.796
2005 Adachi T, Robinson DM, Miles GB, Funk GD. Noradrenergic modulation of XII motoneuron inspiratory activity does not involve alpha2-receptor inhibition of the Ih current or presynaptic glutamate release. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 1297-308. PMID 15579572 DOI: 10.1152/Japplphysiol.00977.2004  0.661
2004 Miles GB, Yohn DC, Wichterle H, Jessell TM, Rafuse VF, Brownstone RM. Functional properties of motoneurons derived from mouse embryonic stem cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7848-58. PMID 15356197 DOI: 10.1523/Jneurosci.1972-04.2004  0.801
2004 Miles GB, Lipski J, Lorier AR, Laslo P, Funk GD. Differential expression of voltage-activated calcium channels in III and XII motoneurones during development in the rat. The European Journal of Neuroscience. 20: 903-13. PMID 15305859 DOI: 10.1111/J.1460-9568.2004.03550.X  0.693
2002 Miles GB, Parkis MA, Lipski J, Funk GD. Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 1899-910. PMID 11960940 DOI: 10.1152/Japplphysiol.00475.2001  0.764
2001 Laslo P, Lipski J, Nicholson LF, Miles GB, Funk GD. GluR2 AMPA receptor subunit expression in motoneurons at low and high risk for degeneration in amyotrophic lateral sclerosis. Experimental Neurology. 169: 461-71. PMID 11358459 DOI: 10.1006/Exnr.2001.7653  0.73
2001 Lorier A, Robinson D, Miles G, Parkis M, Funk G. Differential modulation of inspiratory motoneurons and respiratory rhythm generating circuits by ATP Respiratory Research. 2: 6. DOI: 10.1186/Rr154  0.394
2001 Miles G, Lorier A, Lipski J, Funk G. Differential expression of voltage-activated calcium channels in functionally distinct brainstem motoneurons controlling airway and extraocular muscles Respiratory Research. 2: 32. DOI: 10.1186/Rr150  0.555
2001 Bellingham M, Funk G, Ireland M, Miles G, Robinson D, Selvaratnam S. Contribution of cholinergic systems to state-dependent modulation of respiratory networks Respiratory Research. 2: 1-2. DOI: 10.1186/Rr112  0.775
2000 Laslo P, Lipski J, Nicholson LF, Miles GB, Funk GD. Calcium binding proteins in motoneurons at low and high risk for degeneration in ALS. Neuroreport. 11: 3305-8. PMID 11059892 DOI: 10.1097/00001756-200010200-00009  0.744
2000 Funk GD, Parkis MA, Selvaratnam SR, Robinson DM, Miles GB, Peebles KC. Synaptic control of motoneuron excitability in rodents: from months to milliseconds. Clinical and Experimental Pharmacology & Physiology. 27: 120-5. PMID 10696540 DOI: 10.1046/J.1440-1681.2000.03202.X  0.698
Low-probability matches (unlikely to be authored by this person)
2017 Schubert M, Volckaert K, Karl M, Morton A, Liehm P, Miles GB, Powis SJ, Gather MC. Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators. Scientific Reports. 7: 40877. PMID 28102341 DOI: 10.1038/Srep40877  0.29
2020 Schubert M, Woolfson L, Barnard IRM, Dorward AM, Casement B, Morton A, Robertson GB, Appleton PL, Miles GB, Tucker CS, Pitt SJ, Gather MC. Monitoring contractility in cardiac tissue with cellular resolution using biointegrated microlasers Nature Photonics. 14: 452-458. DOI: 10.1038/S41566-020-0631-Z  0.233
2023 McIntosh J, Mekrouda I, Dashti M, Giuraniuc CV, Banks RW, Miles GB, Bewick GS. Development of abnormalities at the neuromuscular junction in the SOD1-G93A mouse model of ALS: dysfunction then disruption of postsynaptic structure precede overt motor symptoms. Frontiers in Molecular Neuroscience. 16: 1169075. PMID 37273905 DOI: 10.3389/fnmol.2023.1169075  0.222
2019 Morton A, Murawski C, Deng Y, Keum C, Miles GB, Tello JA, Gather MC. Photostimulation for In Vitro Optogenetics with High-Power Blue Organic Light-Emitting Diodes. Advanced Biosystems. 3: e1800290. PMID 32627397 DOI: 10.1002/adbi.201800290  0.194
2021 Strother L, Miles GB, Holiday AR, Cheng Y, Doherty GH. Long-term culture of SH-SY5Y neuroblastoma cells in the absence of neurotrophins: a novel model of neuronal ageing. Journal of Neuroscience Methods. 109301. PMID 34343572 DOI: 10.1016/j.jneumeth.2021.109301  0.099
2014 Miles G, Langlais C, MacFarlane M, Cain K. ‘Aerobically poised’ leukaemia cells are resistant to the mitochondrial toxin and BCL-2/BCL-XL inhibitor, ABT-737 Toxicology Letters. 229: S74. DOI: 10.1016/j.toxlet.2014.06.287  0.051
2020 Powley IR, Patel M, Miles G, Pringle H, Howells L, Thomas A, Kettleborough C, Bryans J, Hammonds T, MacFarlane M, Pritchard C. Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery. British Journal of Cancer. PMID 31894140 DOI: 10.1038/s41416-019-0672-6  0.047
2021 Viticchié G, Powley I, Demetriou C, Cooper J, Butterworth M, Patel M, Abid N, Miles G, Howells L, Pringle H, MacFarlane M, Pritchard C. Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients. Journal of Visualized Experiments : Jove. PMID 33616105 DOI: 10.3791/62130  0.047
1960 Eastham JF, Miles GB. The reaction of certain acid-sensitive steroid ketones with ethanedithiol-borontrifluoride Journal of Organic Chemistry. 25: 826-827.  0.022
1988 Miles GB. One Approach for Teaching Software Engineering Across the Undergraduate Computer Science Curriculum Computer Science Education. 1: 53-62. DOI: 10.1080/0899340880010105  0.01
1986 Miles GB. World congress of faiths: The language of dialogue in world religions Journal of Beliefs & Values. 7: 22-23. DOI: 10.1080/1361767860070205  0.01
1984 Miles GB. Learning about transcendental experience in the sixth form Journal of Beliefs & Values. 5: 1-6. DOI: 10.1080/1361767840050201  0.01
1959 Eastham JF, Miles GB, Krauth CA. Characterization of the products from oxidation of cholestenone with osmium tetroxide Journal of the American Chemical Society. 81: 3114-3120.  0.01
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