Jianxiong Jiang, Ph.D. - Publications

Affiliations: 
2004-2008 Biological Sciences Auburn University, Auburn, AL, United States 
 2008-2014 Pharmacology Emory University School of Medicine, Atlanta, GA, United States 
 2015-2018 College of Pharmacy University of Cincinnati, Cincinnati, OH 
 2018- College of Pharmacy University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Neuropharmacology, Epilepsy, Glioma
Website:
https://jiang.lab.uthsc.edu

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Xu X, Du L, Jiang J, Yang M, Wang Z, Wang Y, Tang T, Fu X, Hao J. Microglial TREM2 Mitigates Inflammatory Responses and Neuronal Apoptosis in Angiotensin II-Induced Hypertension in Middle-Aged Mice. Frontiers in Aging Neuroscience. 13: 716917. PMID 34489683 DOI: 10.3389/fnagi.2021.716917  1
2021 Sluter MN, Hou R, Li L, Yasmen N, Yu Y, Liu J, Jiang J. EP2 Antagonists (2011-2021): A Decade's Journey from Discovery to Therapeutics. Journal of Medicinal Chemistry. PMID 34352171 DOI: 10.1021/acs.jmedchem.1c00816  1
2020 Hou R, Yu Y, Jiang J. PGE2 receptors in detrusor muscle: Drugging the undruggable for urgency. Biochemical Pharmacology. 114363. PMID 33309520 DOI: 10.1016/j.bcp.2020.114363  1
2020 Jiang J, Yu Y. Small molecules targeting cyclooxygenase/prostanoid cascade in experimental brain ischemia: Do they translate? Medicinal Research Reviews. PMID 33094540 DOI: 10.1002/med.21744  1
2020 Li L, Sluter MN, Yu Y, Jiang J. Prostaglandin E receptors as targets for ischemic stroke: Novel evidence and molecular mechanisms of efficacy. Pharmacological Research. 105238. PMID 33053444 DOI: 10.1016/j.phrs.2020.105238  1
2020 Yu Y, Jiang J. COX-2/PGE axis regulates hippocampal BDNF/TrkB signaling via EP2 receptor after prolonged seizures. Epilepsia Open. 5: 418-431. PMID 32913950 DOI: 10.1002/epi4.12409  1
2020 Li L, Yu Y, Hou R, Hao J, Jiang J. Inhibiting the PGE Receptor EP2 Mitigates Excitotoxicity and Ischemic Injury. Acs Pharmacology & Translational Science. 3: 635-643. PMID 32832866 DOI: 10.1021/acsptsci.0c00040  1
2020 Yu Y, Li L, Nguyen DT, Mustafa SM, Moore BM, Jiang J. Inverse Agonism of Cannabinoid Receptor Type 2 Confers Anti-inflammatory and Neuroprotective Effects Following Status Epileptics. Molecular Neurobiology. PMID 32378121 DOI: 10.1007/S12035-020-01923-4  1
2020 Nagib MM, Yu Y, Jiang J. Targeting prostaglandin receptor EP2 for adjunctive treatment of status epilepticus. Pharmacology & Therapeutics. 107504. PMID 32088247 DOI: 10.1016/J.Pharmthera.2020.107504  1
2020 Hou R, Yu Y, Nguyen DT, Sluter MN, Li L, Yang J, Jiang J. Prostaglandin receptor EP2 is a novel molecular target for high-risk neuroblastoma Biorxiv. DOI: https://doi.org/10.1101/2020.02.24.963108  1
2019 Yu Y, Nguyen DT, Jiang J. G protein-coupled receptors in acquired epilepsy: Druggability and translatability. Progress in Neurobiology. 101682. PMID 31454545 DOI: 10.1016/J.Pneurobio.2019.101682  1
2019 Dawn A, Yao X, Yu Y, Jiang J, Kumari H. Assessment of the toxicity of calixarenes and a metal-seamed calixarene: a chemical pathway for clinical application. Supramolecular Chemistry. 31: 425-431. PMID 31371909 DOI: 10.1080/10610278.2019.1616732  1
2019 Jiang J, Yu Y, Kinjo E, Du Y, Nguyen H, Dingledine R. Suppressing pro-inflammatory prostaglandin signaling attenuates excitotoxicity-associated neuronal inflammation and injury. Neuropharmacology. PMID 30763657 DOI: 10.1016/J.Neuropharm.2019.02.011  1
2019 Qiu J, Li Q, Bell KA, Yao X, Du Y, Zhang E, Yu JJ, Yu Y, Shi Z, Jiang J. Small-molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase-associated malignant glioma growth. British Journal of Pharmacology. PMID 30761522 DOI: 10.1111/Bph.14622  1
2018 Jiang J, Van TM, Ganesh T, Dingledine R. Discovery of 2-Piperidinyl Phenyl Benzamides and Trisubstituted Pyrimidines as Positive Allosteric Modulators of the Prostaglandin Receptor EP2. Acs Chemical Neuroscience. PMID 29292987 DOI: 10.1021/Acschemneuro.7B00486  1
2017 Wang H, Yang C, Liu R, Gong K, Hao Q, Wang X, Wu J, Zhang G, Hu Y, Jiang J. Build a Rigid-Flexible Graphene/Silicone Interface by Embedding SiO for Adhesive Application. Acs Omega. 2: 1063-1073. PMID 31457489 DOI: 10.1021/acsomega.7b00017  0.04
2017 Chen M, Zhu G, Wang S, Jiang K, Xu J, Liu J, Jiang J. Simultaneous determination of isomeric substituted anilines by imidization with benzaldehyde and GC-MS. Journal of Separation Science. PMID 29083534 DOI: 10.1002/jssc.201700786  1
2017 Hartings JA, York J, Carroll CP, Hinzman JM, Mahoney E, Krueger B, Winkler MKL, Major S, Horst V, Jahnke P, Woitzik J, Kola V, Du Y, Hagen M, Jiang J, et al. Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction. Brain : a Journal of Neurology. 140: 2673-2690. PMID 28969382 DOI: 10.1093/Brain/Awx214  1
2017 Kang X, Qiu J, Li Q, Bell KA, Du Y, Jung DW, Lee JY, Hao J, Jiang J. Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype. Scientific Reports. 7: 9459. PMID 28842681 DOI: 10.1038/S41598-017-09528-Z  1
2017 Jiang J, Qiu J, Li Q, Shi Z. Prostaglandin E2 Signaling: Alternative Target for Glioblastoma? Trends in Cancer. 3: 75-78. PMID 28718447 DOI: 10.1016/J.Trecan.2016.12.002  1
2017 Qiu J, Du Y, Li Q, Shi Z, Jiang J. Abstract 3114: The role of prostaglandin signaling in human glioblastoma cell activities and growth in vitro and in vivo Cancer Research. 77: 3114-3114. DOI: 10.1158/1538-7445.Am2017-3114  1
2016 Qiu J, Shi Z, Jiang J. Cyclooxygenase-2 in glioblastoma multiforme. Drug Discovery Today. PMID 27693715 DOI: 10.1016/J.Drudis.2016.09.017  1
2016 Li X, Geng X, Xie R, Fu L, Jiang J, Gao L, Sun J. The endophytic bacteria isolated from elephant grass (Pennisetum purpureum Schumach) promote plant growth and enhance salt tolerance of Hybrid Pennisetum. Biotechnology For Biofuels. 9: 190. PMID 27594917 DOI: 10.1186/s13068-016-0592-0  1
2016 Dey A, Kang X, Qiu J, Du Y, Jiang J. Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside. Trends in Pharmacological Sciences. PMID 27062228 DOI: 10.1016/J.Tips.2016.03.001  1
2015 Du Y, Kemper T, Qiu J, Jiang J. Defining the therapeutic time window for suppressing the inflammatory prostaglandin E2 signaling after status epilepticus. Expert Review of Neurotherapeutics. PMID 26689339 DOI: 10.1586/14737175.2016.1134322  1
2015 Wang S, Liu H, Mack J, Tian J, Zou B, Lu H, Li Z, Jiang J, Shen Z. A BODIPY-based 'turn-on' fluorescent probe for hypoxic cell imaging. Chemical Communications (Cambridge, England). PMID 26207944 DOI: 10.1039/c5cc05139h  1
2015 Du Y, Seibenhener ML, Yan J, Jiang J, Wooten MC. aPKC phosphorylation of HDAC6 results in increased deacetylation activity. Plos One. 10: e0123191. PMID 25860570 DOI: 10.1371/Journal.Pone.0123191  1
2015 Shang X, Chai Q, Zhang Q, Jiang J, Zhang T, Guo W, Ruan YL. Down-regulation of the cotton endo-1,4-β-glucanase gene KOR1 disrupts endosperm cellularization, delays embryo development, and reduces early seedling vigour. Journal of Experimental Botany. 66: 3071-83. PMID 25805716 DOI: 10.1093/jxb/erv111  0.04
2015 Fu Y, Yang MS, Jiang J, Ganesh T, Joe E, Dingledine R. EP2 Receptor Signaling Regulates Microglia Death. Molecular Pharmacology. 88: 161-70. PMID 25715797 DOI: 10.1124/Mol.115.098202  1
2015 Jiang J, Yang MS, Quan Y, Gueorguieva P, Ganesh T, Dingledine R. Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus. Neurobiology of Disease. 76: 126-36. PMID 25600211 DOI: 10.1016/J.Nbd.2014.12.032  1
2015 Shi Y, Li W, Li A, Ge R, Zhang B, Li J, Liu G, Li J, Liu A, Shang H, Gong J, Gong W, Yang Z, Tang F, Liu Z, ... ... Jiang J, et al. Constructing a high-density linkage map for Gossypium hirsutum × Gossypium barbadense and identifying QTLs for lint percentage. Journal of Integrative Plant Biology. 57: 450-67. PMID 25263268 DOI: 10.1111/jipb.12288  1
2015 Varvel NH, Jiang J, Dingledine R. Candidate drug targets for prevention or modification of epilepsy. Annual Review of Pharmacology and Toxicology. 55: 229-47. PMID 25196047 DOI: 10.1146/Annurev-Pharmtox-010814-124607  1
2014 Ji L, Hu R, Jiang J, Qi G, Yang X, Zhu M, Fu C, Zhou G, Yi Z. Molecular cloning and expression analysis of 13 NAC transcription factors in Miscanthus lutarioriparius. Plant Cell Reports. 33: 2077-92. PMID 25224554 DOI: 10.1007/s00299-014-1682-8  0.01
2014 Zhang H, Xiong C, Liu F, Zheng X, Jiang J, Zheng Q, Yao C. Optimization of conditions for Cu(II) adsorption on D151 resin from aqueous solutions using response surface methodology and its mechanism study. Water Science and Technology : a Journal of the International Association On Water Pollution Research. 69: 2446-51. PMID 24960006 DOI: 10.2166/wst.2014.163  1
2014 Ganesh T, Jiang J, Dingledine R. Development of second generation EP2 antagonists with high selectivity. European Journal of Medicinal Chemistry. 82: 521-35. PMID 24937185 DOI: 10.1016/J.Ejmech.2014.05.076  1
2014 Ganesh T, Jiang J, Yang MS, Dingledine R. Lead optimization studies of cinnamic amide EP2 antagonists. Journal of Medicinal Chemistry. 57: 4173-84. PMID 24773616 DOI: 10.1021/Jm5000672  1
2014 Zheng Y, Xiong C, Yao C, Ye F, Jiang J, Zheng X, Zheng Q. Adsorption performance and mechanism for removal of Cd(II) from aqueous solutions by D001 cation-exchange resin. Water Science and Technology : a Journal of the International Association On Water Pollution Research. 69: 833-9. PMID 24569284 DOI: 10.2166/wst.2013.756  1
2014 Rojas A, Jiang J, Ganesh T, Yang MS, Lelutiu N, Gueorguieva P, Dingledine R. Cyclooxygenase-2 in epilepsy. Epilepsia. 55: 17-25. PMID 24446952 DOI: 10.1111/Epi.12461  1
2013 Yan J, Seibenhener ML, Calderilla-Barbosa L, Diaz-Meco MT, Moscat J, Jiang J, Wooten MW, Wooten MC. SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity. Plos One. 8: e76016. PMID 24086678 DOI: 10.1371/Journal.Pone.0076016  1
2013 Ganesh T, Jiang J, Shashidharamurthy R, Dingledine R. Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists. Acs Medicinal Chemistry Letters. 4: 616-621. PMID 23914286 DOI: 10.1021/Ml400112H  1
2013 Jiang J, Dingledine R. Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection. Trends in Pharmacological Sciences. 34: 413-23. PMID 23796953 DOI: 10.1016/J.Tips.2013.05.003  1
2013 Seibenhener ML, Zhao T, Du Y, Calderilla-Barbosa L, Yan J, Jiang J, Wooten MW, Wooten MC. Behavioral effects of SQSTM1/p62 overexpression in mice: support for a mitochondrial role in depression and anxiety. Behavioural Brain Research. 248: 94-103. PMID 23591541 DOI: 10.1016/J.Bbr.2013.04.006  1
2013 Quan Y, Jiang J, Dingledine R. EP2 receptor signaling pathways regulate classical activation of microglia. The Journal of Biological Chemistry. 288: 9293-302. PMID 23404506 DOI: 10.1074/Jbc.M113.455816  1
2013 Jiang J, Quan Y, Ganesh T, Pouliot WA, Dudek FE, Dingledine R. Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation. Proceedings of the National Academy of Sciences of the United States of America. 110: 3591-6. PMID 23401547 DOI: 10.1073/Pnas.1218498110  1
2013 Jiang J, Dingledine R. Role of prostaglandin receptor EP2 in the regulations of cancer cell proliferation, invasion, and inflammation. The Journal of Pharmacology and Experimental Therapeutics. 344: 360-7. PMID 23192657 DOI: 10.1124/Jpet.112.200444  1
2012 Jiang J, Ganesh T, Du Y, Quan Y, Serrano G, Qui M, Speigel I, Rojas A, Lelutiu N, Dingledine R. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2. Proceedings of the National Academy of Sciences of the United States of America. 109: 3149-54. PMID 22323596 DOI: 10.1073/Pnas.1120195109  1
2011 Lu H, Wang Q, Li Z, Lai G, Jiang J, Shen Z. A specific chemodosimeter for fluoride ion based on a pyrene derivative with trimethylsilylethynyl groups. Organic & Biomolecular Chemistry. 9: 4558-62. PMID 21526250 DOI: 10.1039/c1ob05164d  1
2010 Jiang J, Ganesh T, Du Y, Thepchatri P, Rojas A, Lewis I, Kurtkaya S, Li L, Qui M, Serrano G, Shaw R, Sun A, Dingledine R. Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor. Proceedings of the National Academy of Sciences of the United States of America. 107: 2307-12. PMID 20080612 DOI: 10.1073/Pnas.0909310107  1
2009 Xu Z, Jin J, Li Z, Qiu H, Jiang J, Lai G, Kira M. Remarkable substituent effects on the activation energy of silylene insertion into silicon-chlorine bonds. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 8605-12. PMID 19658138 DOI: 10.1002/Chem.200901285  1
2009 Jiang J, Parameshwaran K, Seibenhener ML, Kang MG, Suppiramaniam V, Huganir RL, Diaz-Meco MT, Wooten MW. AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62. Hippocampus. 19: 392-406. PMID 19004011 DOI: 10.1002/Hipo.20528  1
2008 Jadhav T, Geetha T, Jiang J, Wooten MW. Identification of a consensus site for TRAF6/p62 polyubiquitination. Biochemical and Biophysical Research Communications. 371: 521-4. PMID 18457658 DOI: 10.1016/J.Bbrc.2008.04.138  1
2006 Jiang J, Suppiramaniam V, Wooten MW. Posttranslational modifications and receptor-associated proteins in AMPA receptor trafficking and synaptic plasticity. Neuro-Signals. 15: 266-82. PMID 17622793 DOI: 10.1159/000105517  1
2005 Geetha T, Jiang J, Wooten MW. Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling. Molecular Cell. 20: 301-12. PMID 16246731 DOI: 10.1016/J.Molcel.2005.09.014  1
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