Zhengyuan Xia, Ph.D. - Publications

Affiliations: 
2004 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Pathology, Medicine and Surgery, Pharmacology

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jiang Y, Cai Y, Han R, Xu Y, Xia Z, Xia W. Salvianolic acids and its potential for cardio-protection against myocardial ischemic reperfusion injury in diabetes. Frontiers in Endocrinology. 14: 1322474. PMID 38283744 DOI: 10.3389/fendo.2023.1322474  0.326
2023 Wang R, Dong S, Xia R, Sun M, Sun Y, Ren H, Zhang Y, Xia Z, Yao S, Wang T. Kinsenoside mitigates myocardial ischemia/reperfusion-induced ferroptosis via activation of the Akt/Nrf2/HO-1 pathway. European Journal of Pharmacology. 956: 175985. PMID 37572943 DOI: 10.1016/j.ejphar.2023.175985  0.326
2023 Zhang X, Wang C, Xu H, Cai S, Liu K, Li S, Chen L, Shen S, Gu X, Tang J, Xia Z, Hu Z, Ma X, Zhang L. Propofol inhibits myocardial injury induced by microvesicles derived from hypoxia-reoxygenated endothelial cells via lncCCT4-2/CCT4 signaling. Biological Research. 56: 20. PMID 37143143 DOI: 10.1186/s40659-023-00428-3  0.31
2022 Sun M, Wang R, Xia R, Xia Z, Wu Z, Wang T. Amelioration of myocardial ischemia/reperfusion injury in diabetes: A narrative review of the mechanisms and clinical applications of dexmedetomidine. Frontiers in Pharmacology. 13: 949754. PMID 36120296 DOI: 10.3389/fphar.2022.949754  0.343
2021 Han RH, Huang HM, Han H, Chen H, Zeng F, Xie X, Liu DY, Cai Y, Zhang LQ, Liu X, Xia ZY, Tang J. Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia. Military Medical Research. 8: 58. PMID 34753510 DOI: 10.1186/s40779-021-00353-0  0.32
2021 Zeng F, Luo J, Han H, Xie W, Wang L, Han R, Chen H, Cai Y, Huang H, Xia Z. Allopurinol ameliorates liver injury in type 1 diabetic rats through activating Nrf2. International Journal of Immunopathology and Pharmacology. 35: 20587384211031417. PMID 34240649 DOI: 10.1177/20587384211031417  0.308
2020 Wang S, Ge L, Zhang D, Wang L, Liu H, Ye X, Liang W, Li J, Ma H, Cai Y, Xia Z. MiR-181c-5p Promotes Inflammatory Response during Hypoxia/Reoxygenation Injury by Downregulating Protein Tyrosine Phosphatase Nonreceptor Type 4 in H9C2 Cardiomyocytes. Oxidative Medicine and Cellular Longevity. 2020: 7913418. PMID 32774684 DOI: 10.1155/2020/7913418  0.348
2020 Peng K, Liu H, Yan B, Meng XW, Song SY, Ji FH, Xia Z. Inhibition of cathepsin S attenuates myocardial ischemia/reperfusion injury by suppressing inflammation and apoptosis. Journal of Cellular Physiology. PMID 32657442 DOI: 10.1002/jcp.29938  0.301
2020 Yan D, Cai Y, Luo J, Liu J, Li X, Ying F, Xie X, Xu A, Ma X, Xia Z. FOXO1 contributes to diabetic cardiomyopathy via inducing imbalanced oxidative metabolism in type 1 diabetes. Journal of Cellular and Molecular Medicine. PMID 32450616 DOI: 10.1111/Jcmm.15418  0.386
2020 Wang C, Yuan W, Hu A, Lin J, Xia Z, Yang CF, Li Y, Zhang Z. Dexmedetomidine alleviated sepsis‑induced myocardial ferroptosis and septic heart injury. Molecular Medicine Reports. PMID 32377745 DOI: 10.3892/Mmr.2020.11114  0.42
2020 Wang C, Zhu L, Yuan W, Sun L, Xia Z, Zhang Z, Yao W. Diabetes aggravates myocardial ischaemia reperfusion injury via activating Nox2-related programmed cell death in an AMPK-dependent manner. Journal of Cellular and Molecular Medicine. PMID 32351005 DOI: 10.1111/Jcmm.15318  0.436
2020 Wang Y, Zhou L, Su W, Huang F, Zhang Y, Xia ZY, Xia Z, Lei S. Selective Inhibition of PKC2 Restores Ischemic Postconditioning-Mediated Cardioprotection by Modulating Autophagy in Diabetic Rats. Journal of Diabetes Research. 2020: 2408240. PMID 32337288 DOI: 10.1155/2020/2408240  0.452
2020 Zhu Q, Li H, Xie X, Chen X, Kosuru R, Li S, Lian Q, Cheung CW, Irwin MG, Ge RS, Xia Z. Adiponectin Facilitates Postconditioning Cardioprotection through Both AMPK-Dependent Nuclear and AMPK-Independent Mitochondrial STAT3 Activation. Oxidative Medicine and Cellular Longevity. 2020: 4253457. PMID 32190173 DOI: 10.1155/2020/4253457  0.39
2020 Zhang D, He Y, Ye X, Cai Y, Xu J, Zhang L, Li M, Liu H, Wang S, Xia Z. Activation of autophagy inhibits NLRP3 inflammasome activation and attenuates myocardial ischemia-reperfusion injury in diabetic rats. Journal of Diabetes Investigation. PMID 32064785 DOI: 10.1111/Jdi.13235  0.446
2020 Cai Y, Ying F, Liu H, Ge L, Song E, Wang L, Zhang D, Hoi Ching Tang E, Xia Z, Irwin MG. Deletion of Rap1 protects against myocardial ischemia/reperfusion injury through suppressing cell apoptosis via activation of STAT3 signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32020680 DOI: 10.1096/Fj.201901592Rr  0.437
2020 Zhang D, Long R, Liu Y, He Y, Sun Y, Xia Z, Wang S. Effects of hypoxia/reoxygenation on apoptosis, autophagy and pyroptosis in H9C2 cardiomyocytes International Journal of Anesthesiology and Resuscitation. 41: 238-243. DOI: 10.3760/Cma.J.Issn.1673-4378.2020.03.003  0.327
2020 Wang L, Liu H, Cai Y, Zhang L, Irwin MG, Xia Z. Repressor Activator Protein 1 Worsens Cardiomyopathy in Diet-induced Type 2 Diabetic Mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09951  0.311
2020 Xiaodong Y, Cai Y, Wang T, Li X, Wang S, Wu Q, Liu D, Irwin MG, Xia Z. Repeated remote ischemic preconditioning enhances post‐ischemic myocardial STAT5A and STAT3 but not STAT5B to confer cardioprotection in diabetic rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09040  0.389
2020 He Y, Cai Y, Irwin MG, Xia Z. Interplay of microRNA‐503 and N‐acetylcysteine in regulating hypoxia‐reoxygenation injury in cardiomyocyte H9C2 cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07604  0.339
2020 Ye X, Cai Y, Zhang D, Wang S, Liu D, Irwin MG, Xia Z. Role of Thioredoxin‐interacting Protein in Diabetic Myocardial Ischemia‐Reperfusion Injury The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03943  0.404
2020 Cai Y, Xie X, Pan Q, Zhi Q, Woolford MG, Xia Z. Rap1 exacerbates myocardial ischemia/reperfusion injury through activation of NFκB signaling pathway and NLRP3 inflammasome The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03220  0.385
2019 Luo J, Yan D, Li S, Liu S, Zeng F, Cheung CW, Liu H, Irwin MG, Huang H, Xia Z. Allopurinol reduces oxidative stress and activates Nrf2/p62 to attenuate diabetic cardiomyopathy in rats. Journal of Cellular and Molecular Medicine. PMID 31856386 DOI: 10.1111/Jcmm.14870  0.434
2019 Lei S, Su W, Xia ZY, Wang Y, Zhou L, Qiao S, Zhao B, Xia Z, Irwin MG. Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling. Oxidative Medicine and Cellular Longevity. 2019: 9836302. PMID 31583053 DOI: 10.1155/2019/9836302  0.449
2019 Sun L, Ma W, Gao W, Xing Y, Chen L, Xia Z, Zhang Z, Dai Z. Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome. Cell Death & Disease. 10: 542. PMID 31316052 DOI: 10.1038/S41419-019-1761-4  0.302
2019 Ge L, Cai Y, Ying F, Liu H, Zhang D, He Y, Pang L, Yan D, Xu A, Ma H, Xia Z. miR-181c-5p Exacerbates Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Targeting PTPN4. Oxidative Medicine and Cellular Longevity. 2019: 1957920. PMID 31178952 DOI: 10.1155/2019/1957920  0.331
2019 Zhu D, Fan T, Huo X, Cui J, Cheung CW, Xia Z. Progressive Increase of Inflammatory CXCR4 and TNF-Alpha in the Dorsal Root Ganglia and Spinal Cord Maintains Peripheral and Central Sensitization to Diabetic Neuropathic Pain in Rats. Mediators of Inflammation. 2019: 4856156. PMID 31001066 DOI: 10.1155/2019/4856156  0.331
2019 Ge ZD, Lian Q, Mao X, Xia Z. Current Status and Challenges of NRF2 as a Potential Therapeutic Target for Diabetic Cardiomyopathy. International Heart Journal. PMID 30971629 DOI: 10.1536/Ihj.18-476  0.382
2019 Wang TT, Shi MM, Liao XL, Li YQ, Yuan HX, Li Y, Liu X, Ning DS, Peng YM, Yang F, Mo ZW, Jiang YM, Xu YQ, Li H, Wang M, ... ... Xia Z, et al. Overexpression of inducible nitric oxide synthase in the diabetic heart compromises ischemic postconditioning. Journal of Molecular and Cellular Cardiology. PMID 30797815 DOI: 10.1016/J.Yjmcc.2019.02.011  0.402
2019 Zhang D, Wang S, Ye X, Cai Y, He Y, Xia Z. Repeated non-invasive limb ischemic preconditioning attenuates myocardial ischemia-reperfusion injury in diabetic rats by up-regulating hexokinase II The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.514.1  0.417
2018 Xie X, Yan D, Li H, Zhu Q, Li J, Fang YP, Cheung CW, Irwin MG, Xia Z, Lian Q. Enhancement of Adiponectin Ameliorates Nonalcoholic Fatty Liver Disease via Inhibition of FoxO1 in Type I Diabetic Rats. Journal of Diabetes Research. 2018: 6254340. PMID 30186875 DOI: 10.1155/2018/6254340  0.345
2018 Li H, Xia Z, Chen Y, Qi D, Zheng H. Mechanism and Therapies of Oxidative Stress-Mediated Cell Death in Ischemia Reperfusion Injury. Oxidative Medicine and Cellular Longevity. 2018: 2910643. PMID 30034574 DOI: 10.1155/2018/2910643  0.369
2018 Liu Y, Paterson M, Baumgardt SL, Irwin MG, Xia Z, Bosnjak ZJ, Ge ZD. VEGF Regulation of eNOS Phosphorylation Is Involved in Isoflurane Cardiac Preconditioning. Cardiovascular Research. PMID 29931049 DOI: 10.1093/Cvr/Cvy157  0.31
2018 Ye XD, He Y, Wang S, Wong GT, Irwin MG, Xia Z. Heart-type fatty acid binding protein (H-FABP) as a biomarker for acute myocardial injury and long-term post-ischemic prognosis. Acta Pharmacologica Sinica. PMID 29770799 DOI: 10.1038/Aps.2018.37  0.37
2018 Kosuru R, Cai Y, Kandula V, Yan D, Wang C, Zheng H, Li Y, Irwin MG, Singh S, Xia Z. AMPK Contributes to Cardioprotective Effects of Pterostilbene Against Myocardial Ischemia- Reperfusion Injury in Diabetic Rats by Suppressing Cardiac Oxidative Stress and Apoptosis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 46: 1381-1397. PMID 29689567 DOI: 10.1159/000489154  0.454
2018 Wang C, Li H, Wang S, Mao X, Yan D, Wong SS, Xia Z, Irwin MG. Repeated Non-Invasive Limb Ischemic Preconditioning Confers Cardioprotection Through PKC-Ԑ/STAT3 Signaling in Diabetic Rats. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 45: 2107-2121. PMID 29533954 DOI: 10.1159/000488047  0.423
2017 Deng F, Wang S, Zhang L, Xie X, Cai S, Li H, Xie GL, Miao HL, Yang C, Liu X, Xia Z. Propofol Through Upregulating Caveolin-3 Attenuates Post-Hypoxic Mitochondrial Damage and Cell Death in H9C2 Cardiomyocytes During Hyperglycemia. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 44: 279-292. PMID 29130958 DOI: 10.1159/000484680  0.312
2017 Gao S, Zhan L, Yang Z, Shi R, Li H, Xia Z, Yuan S, Wu QP, Wang T, Yao S. Remote Limb Ischaemic Postconditioning Protects Against Myocardial Ischaemia/Reperfusion Injury in Mice: Activation of JAK/STAT3-Mediated Nrf2-Antioxidant Signalling. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 43: 1140-1151. PMID 28977786 DOI: 10.1159/000481755  0.406
2017 Cheng Y, Feng Y, Xia Z, Li X, Rong J. ω-Alkynyl arachidonic acid promotes anti-inflammatory macrophage M2 polarization against acute myocardial infarction via regulating the cross-talk between PKM2, HIF-1α and iNOS. Biochimica Et Biophysica Acta. PMID 28964797 DOI: 10.1016/J.Bbalip.2017.09.009  0.316
2017 Gan X, Xing D, Su G, Li S, Luo C, Irwin MG, Xia Z, Li H, Hei Z. Corrigendum to "Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation". Oxidative Medicine and Cellular Longevity. 2017: 8932871. PMID 28883906 DOI: 10.1155/2017/8932871  0.376
2017 Cai Y, Kandula V, Kosuru R, Ye X, Irwin MG, Xia Z. Decoding telomere protein Rap1: Its telomeric and nontelomeric functions and potential implications in diabetic cardiomyopathy. Cell Cycle (Georgetown, Tex.). 0. PMID 28853973 DOI: 10.1080/15384101.2017.1371886  0.319
2017 Liu Y, Baumgardt SL, Fang J, Shi Y, Qiao S, Bosnjak ZJ, Vásquez-Vivar J, Xia Z, Warltier DC, Kersten JR, Ge ZD. Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling. Scientific Reports. 7: 3093. PMID 28596578 DOI: 10.1038/S41598-017-03234-6  0.352
2017 Ge M, Yao W, Yuan D, Zhou S, Chen X, Zhang Y, Li H, Xia Z, Hei Z. Brg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia-reperfusion injury. Cell Death & Disease. 8: e2841. PMID 28569786 DOI: 10.1038/Cddis.2017.236  0.377
2017 Yao W, Li H, Luo G, Li X, Chen C, Yuan D, Chi X, Xia Z, Hei Z. SERPINB1 Ameliorates Acute Lung Injury in Liver Transplantation Through ERK1/2-mediated STAT3-dependent HO-1 Induction. Free Radical Biology & Medicine. PMID 28427999 DOI: 10.1016/J.Freeradbiomed.2017.04.011  0.317
2017 Zhou B, Lei S, Xue R, Leng Y, Xia Z, Xia ZY. DJ-1 overexpression restores ischaemic post-conditioning-mediated cardioprotection in diabetic rats :role of autophagy. Clinical Science (London, England : 1979). PMID 28404768 DOI: 10.1042/Cs20170052  0.467
2017 Yao W, Li H, Han X, Chen C, Zhang Y, Tai WL, Xia Z, Hei Z. MG53 anchored by dysferlin to cell membrane reduces hepatocyte apoptosis which induced by ischaemia/reperfusion injury in vivo and in vitro. Journal of Cellular and Molecular Medicine. PMID 28401647 DOI: 10.1111/Jcmm.13171  0.386
2017 Wu Q, Wang T, Chen S, Zhou Q, Li H, Hu N, Feng Y, Dong N, Yao S, Xia Z. Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial. European Heart Journal. PMID 28329231 DOI: 10.1093/Eurheartj/Ehx030  0.321
2017 Wang S, Wang C, Yan F, Wang T, He Y, Li H, Xia Z, Zhang Z. N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy. Mediators of Inflammation. 2017: 9257291. PMID 28265179 DOI: 10.1155/2017/9257291  0.466
2017 Qi D, Xia Z, Zhuang Z. Metabolic Mechanisms and Potential Therapies of Diabetic Cardiac Complications. Journal of Diabetes Research. 2017: 5130496. PMID 28180129 DOI: 10.1155/2017/5130496  0.325
2016 Pang L, Cai Y, Tang EH, Yan D, Kosuru R, Li H, Irwin MG, Ma H, Xia Z. Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS Expression. Oxidative Medicine and Cellular Longevity. 2016: 3453059. PMID 27795807 DOI: 10.1155/2016/3453059  0.374
2016 Su W, Zhang Y, Zhang Q, Xu J, Zhan L, Zhu Q, Lian Q, Liu H, Xia ZY, Xia Z, Lei S. N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats. Cardiovascular Diabetology. 15: 146. PMID 27733157 DOI: 10.1186/S12933-016-0460-Z  0.452
2016 Cheng YY, Luo D, Xia Z, Tse HF, Li X, Rong J. In Vivo Cardioprotective Effects and Pharmacokinetic Profile of N-Propyl Caffeamide Against Ischemia Reperfusion Injury. Archivum Immunologiae Et Therapiae Experimentalis. PMID 27480649 DOI: 10.1007/S00005-016-0413-Y  0.404
2016 Han X, Yao W, Liu Z, Li H, Zhang ZJ, Hei Z, Xia Z. Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner. Oxidative Medicine and Cellular Longevity. 2016: 9303606. PMID 27375835 DOI: 10.1155/2016/9303606  0.417
2016 Gao S, Zhu Y, Li H, Xia Z, Wu Q, Yao S, Wang T, Yuan S. Remote ischemic postconditioning protects against renal ischemia/reperfusion injury by activation of T-LAK-cell-originated protein kinase (TOPK)/PTEN/Akt signaling pathway mediated anti-oxidation and anti-inflammation. International Immunopharmacology. 38: 395-401. PMID 27355132 DOI: 10.1016/J.Intimp.2016.06.020  0.372
2016 Wang L, Wang T, Li H, Liu Q, Zhang Z, Xie W, Feng Y, Socorburam T, Wu G, Xia Z, Wu Q. Receptor Interacting Protein 3-Mediated Necroptosis Promotes Lipopolysaccharide-Induced Inflammation and Acute Respiratory Distress Syndrome in Mice. Plos One. 11: e0155723. PMID 27195494 DOI: 10.1371/Journal.Pone.0155723  0.326
2016 Pang L, Cai Y, Tang EH, Irwin MG, Ma H, Xia Z. Prostaglandin E Receptor Subtype 4 Signaling in the Heart: Role in Ischemia/Reperfusion Injury and Cardiac Hypertrophy. Journal of Diabetes Research. 2016: 1324347. PMID 27190998 DOI: 10.1155/2016/1324347  0.36
2016 Zhuang H, Tian W, Li W, Zhang X, Wang J, Yang Y, Liu X, Xia Z, Feng D, Zhang L. Autophagic Cell Death and Apoptosis Jointly Mediate Cisatracurium Besylate-Induced Cell Injury. International Journal of Molecular Sciences. 17. PMID 27058536 DOI: 10.3390/Ijms17040515  0.325
2016 Cheng Y, Xia Z, Han Y, Rong J. Plant Natural Product Formononetin Protects Rat Cardiomyocyte H9c2 Cells against Oxygen Glucose Deprivation and Reoxygenation via Inhibiting ROS Formation and Promoting GSK-3β Phosphorylation. Oxidative Medicine and Cellular Longevity. 2016: 2060874. PMID 27034732 DOI: 10.1155/2016/2060874  0.315
2016 Gao S, Yang Z, Shi R, Xu D, Li H, Xia Z, Wu QP, Yao S, Wang T, Yuan S. Diabetes blocks the cardioprotective effects of sevoflurane postconditioning by impairing Nrf2/Brg1/HO-1 signaling. European Journal of Pharmacology. PMID 26973173 DOI: 10.1016/J.Ejphar.2016.03.018  0.461
2016 Kandula V, Kosuru R, Li H, Yan D, Zhu Q, Lian Q, Ge RS, Xia Z, Irwin MG. Forkhead box transcription factor 1: role in the pathogenesis of diabetic cardiomyopathy. Cardiovascular Diabetology. 15: 44. PMID 26956801 DOI: 10.1186/S12933-016-0361-1  0.368
2016 Wang Y, Li H, Huang H, Liu S, Mao X, Wang S, Wong SS, Xia Z, Irwin MG. Emulsified Isoflurane Postconditioning Cardioprotection is Lost in Rats with Streptozotocin-induced Diabetes Due to The Impairment of Brg1/Nrf2/STAT3 Signaling. Clinical Science (London, England : 1979). PMID 26846682 DOI: 10.1042/Cs20150617  0.465
2016 Lin J, Wang T, Li Y, Wang M, Li H, Irwin MG, Xia Z. N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats. Journal of Diabetes Research. 2016: 9213034. PMID 26783539 DOI: 10.1155/2016/9213034  0.423
2016 Yu X, Chi X, Wu S, Jin Y, Yao H, Wang Y, Xia Z, Cai J. Dexmedetomidine Pretreatment Attenuates Kidney Injury and Oxidative Stress during Orthotopic Autologous Liver Transplantation in Rats. Oxidative Medicine and Cellular Longevity. 2016: 4675817. PMID 26682005 DOI: 10.1155/2016/4675817  0.317
2015 Li H, Yao W, Liu Z, Xu A, Huang Y, Ma XL, Irwin MG, Xia Z. Hyperglycemia Abrogates Ischemic Postconditioning Cardioprotection by Impairing AdipoR1/Caveolin-3/STAT3 Signaling in Diabetic Rats. Diabetes. PMID 26718505 DOI: 10.2337/Db15-0782  0.443
2015 Xue R, Lei S, Xia ZY, Wu Y, Meng Q, Zhan L, Su W, Liu H, Xu J, Liu Z, Zhou B, Xia Z. Selective Inhibition of PTEN Preserves Ischemic Postconditioning Cardioprotection in STZ-induced Type1 Diabetic Rats: Role of the PI3K/ Akt and JAK2/ STAT3 Pathways. Clinical Science (London, England : 1979). PMID 26666444 DOI: 10.1042/Cs20150496  0.434
2015 Yao H, Chi X, Jin Y, Wang Y, Huang P, Wu S, Xia Z, Cai J. Dexmedetomidine Inhibits TLR4/NF-κB Activation and Reduces Acute Kidney Injury after Orthotopic Autologous Liver Transplantation in Rats. Scientific Reports. 5: 16849. PMID 26585410 DOI: 10.1038/Srep16849  0.364
2015 Yao X, Li Y, Tao M, Wang S, Zhang L, Lin J, Xia Z, Liu HM. Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts. Journal of Diabetes Research. 2015: 592028. PMID 26491698 DOI: 10.1155/2015/592028  0.4
2015 Chi X, Yao W, Zhang A, Ge M, Cai J, Zhou S, Xia Z, Luo G, Hei Z. Downregulation of Lung Toll-Like Receptor 4 Could Effectively Attenuate Liver Transplantation-Induced Pulmonary Damage at the Early Stage of Reperfusion. Mediators of Inflammation. 2015: 383907. PMID 26491225 DOI: 10.1155/2015/383907  0.314
2015 Qiao S, Mao X, Wang Y, Lei S, Liu Y, Wang T, Wong GT, Cheung CW, Xia Z, Irwin MG. Remifentanil Preconditioning Reduces Postischemic Myocardial Infarction and Improves Left Ventricular Performance via Activation of the Janus Activated Kinase-2/Signal Transducers and Activators of Transcription-3 Signal Pathway and Subsequent Inhibition of Glycogen Synthase Kinase-3β in Rats. Critical Care Medicine. PMID 26468894 DOI: 10.1097/Ccm.0000000000001350  0.328
2015 Yu HP, Chaudry IH, Choudhry MA, Hsing CH, Liu FC, Xia Z. Inflammatory Response to Traumatic Injury: Clinical and Animal Researches in Inflammation. Mediators of Inflammation. 2015: 729637. PMID 26290624 DOI: 10.1155/2015/729637  0.37
2015 Tian Y, Li H, Liu P, Xu JM, Irwin MG, Xia Z, Tian G. Captopril Pretreatment Produces an Additive Cardioprotection to Isoflurane Preconditioning in Attenuating Myocardial Ischemia Reperfusion Injury in Rabbits and in Humans. Mediators of Inflammation. 2015: 819232. PMID 26273143 DOI: 10.1155/2015/819232  0.4
2015 Xia Z, Chen Y, Fan Q, Xue M, Liu KX. Oxidative Stress-Mediated Reperfusion Injury 2014. Oxidative Medicine and Cellular Longevity. 2015: 689416. PMID 26265984 DOI: 10.1155/2015/689416  0.409
2015 Gan X, Xing D, Su G, Li S, Luo C, Irwin MG, Xia Z, Li H, Hei Z. Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation. Oxidative Medicine and Cellular Longevity. 2015: 167014. PMID 26246867 DOI: 10.1155/2015/167014  0.413
2015 Zhou M, Bao Y, Li H, Pan Y, Shu L, Xia Z, Wu D, Lam KS, Vanhoutte PM, Xu A, Jia W, Hoo RL. Deficiency of adipocyte fatty-acid-binding protein alleviates myocardial ischaemia/reperfusion injury and diabetes-induced cardiac dysfunction. Clinical Science (London, England : 1979). 129: 547-59. PMID 26186740 DOI: 10.1042/Cs20150073  0.428
2015 Jiang Y, Zhou Z, Meng QT, Sun Q, Su W, Lei S, Xia Z, Xia ZY. Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice. Oxidative Medicine and Cellular Longevity. 2015: 843721. PMID 26161243 DOI: 10.1155/2015/843721  0.376
2015 Liu B, Huang W, Xiao X, Xu Y, Ma S, Xia Z. Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits. Oxidative Medicine and Cellular Longevity. 2015: 624819. PMID 26161241 DOI: 10.1155/2015/624819  0.328
2015 Liu Y, Jin J, Qiao S, Lei S, Liao S, Ge ZD, Li H, Wong GT, Irwin MG, Xia Z. Inhibition of PKCβ2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling. Clinical Science (London, England : 1979). 129: 331-44. PMID 25849791 DOI: 10.1042/Cs20140789  0.47
2015 Li S, Xu J, Yao W, Li H, Liu Q, Xiao F, Irwin MG, Xia Z, Ruan W. Sevoflurane pretreatment attenuates TNF-α-induced human endothelial cell dysfunction through activating eNOS/NO pathway. Biochemical and Biophysical Research Communications. 460: 879-86. PMID 25838201 DOI: 10.1016/J.Bbrc.2015.03.126  0.342
2015 Li H, Yao W, Irwin MG, Wang T, Wang S, Zhang L, Xia Z. Adiponectin ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction by concomitantly activating Nrf2 and Brg1. Free Radical Biology & Medicine. 84: 311-21. PMID 25795513 DOI: 10.1016/J.Freeradbiomed.2015.03.007  0.444
2015 Luo C, Yuan D, Li X, Yao W, Luo G, Chi X, Li H, Irwin MG, Xia Z, Hei Z. Propofol attenuated acute kidney injury after orthotopic liver transplantation via inhibiting gap junction composed of connexin 32. Anesthesiology. 122: 72-86. PMID 25254904 DOI: 10.1097/Aln.0000000000000448  0.326
2015 Lei S, Su W, Xue R, Liu H, Zhang L, Miao H, Liu Y, Li H, Irwin MG, Xia Z. Opioid-Induced Cardioprotection against Ischemia-Reperfusion Injury: The Challenge in Diabetes Journal of Diabetes & Metabolism. 6: 1-4. DOI: 10.4172/2155-6156.1000616  0.404
2014 Sun W, Wang ZP, Gui P, Xia W, Xia Z, Zhang XC, Deng QZ, Xuan W, Marie C, Wang LL, Wu QP, Wang T, Lin Y. Endogenous expression pattern of resolvin D1 in a rat model of self-resolution of lipopolysaccharide-induced acute respiratory distress syndrome and inflammation. International Immunopharmacology. 23: 247-53. PMID 25218162 DOI: 10.1016/J.Intimp.2014.09.001  0.34
2014 Xing D, Zhang R, Li S, Huang P, Luo C, Hei Z, Xia Z, Gan X. Pivotal role of mast cell carboxypeptidase A in mediating protection against small intestinal ischemia-reperfusion injury in rats after ischemic preconditioning. The Journal of Surgical Research. 192: 177-86. PMID 24953986 DOI: 10.1016/J.Jss.2014.05.050  0.388
2014 Wen SH, Ling YH, Liu WF, Qiu YX, Li YS, Wu Y, Shen JT, Xia ZY, Liu KX. Role of 15-F2t-isoprostane in intestinal injury induced by intestinal ischemia/reperfusion in rats. Free Radical Research. 48: 907-18. PMID 24848748 DOI: 10.3109/10715762.2014.926010  0.366
2014 Xu J, Li H, Irwin MG, Xia ZY, Mao X, Lei S, Wong GT, Hung V, Cheung CW, Fang X, Clanachan AS, Xia Z. Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats. Critical Care Medicine. 42: e583-94. PMID 24810525 DOI: 10.1097/Ccm.0000000000000415  0.414
2014 Xia Z, Chen Y, Fan Q, Xue M. Oxidative stress-mediated reperfusion injury: mechanism and therapies. Oxidative Medicine and Cellular Longevity. 2014: 373081. PMID 24803980 DOI: 10.1155/2014/373081  0.383
2014 Yao W, Luo G, Zhu G, Chi X, Zhang A, Xia Z, Hei Z. Propofol activation of the Nrf2 pathway is associated with amelioration of acute lung injury in a rat liver transplantation model. Oxidative Medicine and Cellular Longevity. 2014: 258567. PMID 24669282 DOI: 10.1155/2014/258567  0.346
2013 Lei S, Su W, Liu H, Xu J, Xia ZY, Yang QJ, Qiao X, Du Y, Zhang L, Xia Z. Nitroglycerine-induced nitrate tolerance compromises propofol protection of the endothelial cells against TNF-α: the role of PKC-β2 and NADPH oxidase. Oxidative Medicine and Cellular Longevity. 2013: 678484. PMID 24396568 DOI: 10.1155/2013/678484  0.33
2013 Sun Q, Meng QT, Jiang Y, Liu HM, Lei SQ, Su WT, Duan WN, Wu Y, Xia ZY, Xia ZY. Protective effect of ginsenoside Rb1 against intestinal ischemia-reperfusion induced acute renal injury in mice. Plos One. 8: e80859. PMID 24324637 DOI: 10.1371/Journal.Pone.0080859  0.381
2013 Liu M, Zhou B, Xia ZY, Zhao B, Lei SQ, Yang QJ, Xue R, Leng Y, Xu JJ, Xia Z. Hyperglycemia-induced inhibition of DJ-1 expression compromised the effectiveness of ischemic postconditioning cardioprotection in rats. Oxidative Medicine and Cellular Longevity. 2013: 564902. PMID 24303086 DOI: 10.1155/2013/564902  0.465
2013 Zhang A, Chi X, Luo G, Hei Z, Xia H, Luo C, Wang Y, Mao X, Xia Z. Mast cell stabilization alleviates acute lung injury after orthotopic autologous liver transplantation in rats by downregulating inflammation. Plos One. 8: e75262. PMID 24116032 DOI: 10.1371/Journal.Pone.0075262  0.345
2013 Li H, Liu Z, Wang J, Wong GT, Cheung CW, Zhang L, Chen C, Xia Z, Irwin MG. Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats. Cardiovascular Diabetology. 12: 133. PMID 24041262 DOI: 10.1186/1475-2840-12-133  0.409
2013 Mei B, Wang T, Wang Y, Xia Z, Irwin MG, Wong GT. High dose remifentanil increases myocardial oxidative stress and compromises remifentanil infarct-sparing effects in rats. European Journal of Pharmacology. 718: 484-92. PMID 23954793 DOI: 10.1016/J.Ejphar.2013.07.030  0.31
2013 Wang T, Yao S, Xia Z, Irwin MG. Adiponectin: mechanisms and new therapeutic approaches for restoring diabetic heart sensitivity to ischemic post-conditioning. Frontiers of Medicine. 7: 301-5. PMID 23904036 DOI: 10.1007/S11684-013-0283-1  0.418
2013 Mao X, Wang T, Liu Y, Irwin MG, Ou JS, Liao XL, Gao X, Xu Y, Ng KF, Vanhoutte PM, Xia Z. N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats. Plos One. 8: e68949. PMID 23874823 DOI: 10.1371/Journal.Pone.0068949  0.44
2013 Xu J, Lei S, Liu Y, Gao X, Irwin MG, Xia ZY, Hei Z, Gan X, Wang T, Xia Z. Antioxidant N-acetylcysteine attenuates the reduction of Brg1 protein expression in the myocardium of type 1 diabetic rats. Journal of Diabetes Research. 2013: 716219. PMID 23853776 DOI: 10.1155/2013/716219  0.403
2013 Wang T, Mao X, Li H, Qiao S, Xu A, Wang J, Lei S, Liu Z, Ng KF, Wong GT, Vanhoutte PM, Irwin MG, Xia Z. N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes. Free Radical Biology & Medicine. 63: 291-303. PMID 23747931 DOI: 10.1016/J.Freeradbiomed.2013.05.043  0.45
2013 Lei S, Li H, Xu J, Liu Y, Gao X, Wang J, Ng KF, Lau WB, Ma XL, Rodrigues B, Irwin MG, Xia Z. Hyperglycemia-induced protein kinase C β2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling. Diabetes. 62: 2318-28. PMID 23474486 DOI: 10.2337/Db12-1391  0.413
2013 Liu J, Hou J, Xia ZY, Zeng W, Wang X, Li R, Ke C, Xu J, Lei S, Xia Z. Recombinant PTD-Cu/Zn SOD attenuates hypoxia-reoxygenation injury in cardiomyocytes. Free Radical Research. 47: 386-393. PMID 23445361 DOI: 10.3109/10715762.2013.780286  0.304
2013 Liao XL, Hu XX, Chang FJ, Yuan HY, Ci HB, Wu JY, Xu Z, Wang ZP, Zhang X, Xia Z, Ou JS. A simple modification results in greater success in the model of coronary artery ligation and myocardial ischemia in mice. Journal of Cardiovascular Pharmacology. 61: 430-6. PMID 23429589 DOI: 10.1097/Fjc.0B013E318288A68D  0.307
2013 Chi X, Zhang A, Luo G, Xia H, Zhu G, Hei Z, Liu X, Wei J, Xia Z. Knockdown of myeloid differentiation protein-2 reduces acute lung injury following orthotopic autologous liver transplantation in a rat model. Pulmonary Pharmacology & Therapeutics. 26: 380-7. PMID 23428646 DOI: 10.1016/J.Pupt.2013.02.001  0.34
2013 Wu H, Lei S, Yuan J, Liu X, Zhang D, Gu X, Zhang L, Xia Z. Ischemic postconditioning downregulates Egr-1 expression and attenuates postischemic pulmonary inflammatory cytokine release and tissue injury in rats. The Journal of Surgical Research. 181: 204-12. PMID 22878149 DOI: 10.1016/J.Jss.2012.07.031  0.371
2013 Li H, Irwin MG, Tao M, Li Y, Zhang L, Xia Z. Role of Forkhead Transcription Factors in Myocardial Ischemic Reperfusion Injury in Diabetes Journal of Diabetes & Metabolism. 4: 1-6. DOI: 10.4172/2155-6156.1000247  0.436
2012 Zhang YM, Wang CY, Zheng FC, Gao FF, Chen YC, Huang ZQ, Xia ZY, Irwin MG, Li WQ, Liu XP, Zheng YS, Xu H, Shi GG. Effects of N-n-butyl haloperidol iodide on the rat myocardial sarcoplasmic reticulum Ca(2+)-ATPase during ischemia/reperfusion. Biochemical and Biophysical Research Communications. 425: 426-30. PMID 22846577 DOI: 10.1016/J.Bbrc.2012.07.117  0.338
2012 Wong GT, Yao L, Xia Z, Irwin MG. Intrathecal morphine remotely preconditions the heart via a neural pathway. Journal of Cardiovascular Pharmacology. 60: 172-8. PMID 22635074 DOI: 10.1097/Fjc.0B013E31825E2195  0.333
2012 Gao X, Xu Y, Xu B, Liu Y, Cai J, Liu HM, Lei S, Zhong YQ, Irwin MG, Xia Z. Allopurinol attenuates left ventricular dysfunction in rats with early stages of streptozotocin-induced diabetes. Diabetes/Metabolism Research and Reviews. 28: 409-17. PMID 22389139 DOI: 10.1002/Dmrr.2295  0.406
2012 Lei S, Liu Y, Liu H, Yu H, Wang H, Xia Z. Effects of N-acetylcysteine on nicotinamide dinucleotide phosphate oxidase activation and antioxidant status in heart, lung, liver and kidney in streptozotocin-induced diabetic rats. Yonsei Medical Journal. 53: 294-303. PMID 22318816 DOI: 10.3349/Ymj.2012.53.2.294  0.381
2012 Huang P, Liu D, Gan X, Zhang R, Gao W, Xia Z, Hei Z. Mast cells activation contribute to small intestinal ischemia reperfusion induced acute lung injury in rats. Injury. 43: 1250-6. PMID 22277108 DOI: 10.1016/J.Injury.2011.12.027  0.37
2012 Liu KX, Xia Z. Potential synergy of antioxidant N-acetylcysteine and insulin in restoring sevoflurane postconditioning cardioprotection in diabetes. Anesthesiology. 116: 488-9; author reply . PMID 22273863 DOI: 10.1097/Aln.0B013E31823Fd063  0.304
2012 Deng B, Xie S, Wang J, Xia Z, Nie R. Inhibition of protein kinase C β(2) prevents tumor necrosis factor-α-induced apoptosis and oxidative stress in endothelial cells: the role of NADPH oxidase subunits. Journal of Vascular Research. 49: 144-59. PMID 22261918 DOI: 10.1159/000332337  0.325
2012 Li T, Wu W, You Z, Zhou R, Li Q, Zhu D, Li H, Xiang X, Irwin MG, Xia Z, Liu J. Alternative use of isoflurane and propofol confers superior cardioprotection than using one of them alone in a dog model of cardiopulmonary bypass. European Journal of Pharmacology. 677: 138-46. PMID 22222823 DOI: 10.1016/J.Ejphar.2011.12.030  0.401
2012 Liu Y, Lei S, Gao X, Mao X, Wang T, Wong GT, Vanhoutte PM, Irwin MG, Xia Z. PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes. Clinical Science (London, England : 1979). 122: 161-73. PMID 21892921 DOI: 10.1042/Cs20110176  0.424
2012 Wang M, Ji P, Wang R, Zhao L, Xia Z. TRPV1 agonist capsaicin attenuates lung ischemia-reperfusion injury in rabbits. The Journal of Surgical Research. 173: 153-60. PMID 20950828 DOI: 10.1016/J.Jss.2010.08.053  0.364
2011 Wang T, Qiao S, Lei S, Liu Y, Ng KF, Xu A, Lam KS, Irwin MG, Xia Z. N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats. Plos One. 6: e23967. PMID 21912612 DOI: 10.1371/Journal.Pone.0023967  0.465
2011 Xia Z, Vanhoutte PM. Nitric oxide and protection against cardiac ischemia. Current Pharmaceutical Design. 17: 1774-82. PMID 21631419 DOI: 10.2174/138161211796391047  0.361
2011 Huang Z, Zhong X, Irwin MG, Ji S, Wong GT, Liu Y, Xia ZY, Finegan BA, Xia Z. Synergy of isoflurane preconditioning and propofol postconditioning reduces myocardial reperfusion injury in patients. Clinical Science (London, England : 1979). 121: 57-69. PMID 21291422 DOI: 10.1042/Cs20100435  0.372
2011 Xu B, Gao X, Xu J, Lei S, Xia ZY, Xu Y, Xia Z. Ischemic postconditioning attenuates lung reperfusion injury and reduces systemic proinflammatory cytokine release via heme oxygenase 1. The Journal of Surgical Research. 166: e157-64. PMID 21227458 DOI: 10.1016/J.Jss.2010.11.902  0.359
2011 Zhu XH, Yuan HJ, Wu YN, Kang Y, Jiao JJ, Gao WZ, Liu YX, Lou JS, Xia Z. Non-invasive limb ischemic pre-conditioning reduces oxidative stress and attenuates myocardium ischemia-reperfusion injury in diabetic rats. Free Radical Research. 45: 201-10. PMID 20942563 DOI: 10.3109/10715762.2010.522576  0.433
2011 Fan Q, Yang XC, Liu Y, Wang LF, Liu SH, Ge YG, Chen ML, Wang W, Zhang LK, Irwin MG, Xia Z. Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans. Clinical Science (London, England : 1979). 120: 251-61. PMID 20919993 DOI: 10.1042/Cs20100369  0.427
2011 Liu HM, Liu KX, Cheng MH, Liu Y, Lei S, Irwin MG, Xia Z. Bosentan affects 15-F2t-isoprostane adverse effects on postischemic rat hearts. The Journal of Surgical Research. 168: 18-26. PMID 20006348 DOI: 10.1016/J.Jss.2009.07.029  0.401
2010 Liu KX, Li C, Li YS, Yuan BL, Xu M, Xia Z, Huang WQ. Proteomic analysis of intestinal ischemia/reperfusion injury and ischemic preconditioning in rats reveals the protective role of aldose reductase. Proteomics. 10: 4463-75. PMID 21136599 DOI: 10.1002/Pmic.201000078  0.375
2010 Li YS, Wang ZX, Li C, Xu M, Li Y, Huang WQ, Xia Z, Liu KX. Proteomics of ischemia/reperfusion injury in rat intestine with and without ischemic postconditioning. The Journal of Surgical Research. 164: e173-80. PMID 20189595 DOI: 10.1016/J.Jss.2009.10.003  0.359
2010 Xia Z, Luo T, Liu HM, Wang F, Xia ZY, Irwin MG, Vanhoutte PM. L-arginine enhances nitrative stress and exacerbates tumor necrosis factor-alpha toxicity to human endothelial cells in culture: prevention by propofol. Journal of Cardiovascular Pharmacology. 55: 358-67. PMID 20125033 DOI: 10.1097/Fjc.0B013E3181D265A3  0.358
2010 Xia ZY, Gao J, Ancharaz AK, Liu KX, Xia Z, Luo T. Ischaemic post-conditioning protects lung from ischaemia-reperfusion injury by up-regulation of haeme oxygenase-1. Injury. 41: 510-6. PMID 19524915 DOI: 10.1016/J.Injury.2009.03.002  0.356
2009 Tsai GY, Cui JZ, Syed H, Xia Z, Ozerdem U, McNeill JH, Matsubara JA. Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats. Clinical & Experimental Ophthalmology. 37: 223-31. PMID 19723131 DOI: 10.1111/J.1442-9071.2009.02000.X  0.336
2009 Liu KX, Li YS, Huang WQ, Chen SQ, Wang ZX, Liu JX, Xia Z. Immediate postconditioning during reperfusion attenuates intestinal injury. Intensive Care Medicine. 35: 933-42. PMID 19190893 DOI: 10.1007/S00134-009-1428-1  0.401
2008 Liu KX, Chen SQ, Huang WQ, Li YS, Irwin MG, Xia Z. Propofol pretreatment reduces ceramide production and attenuates intestinal mucosal apoptosis induced by intestinal ischemia/reperfusion in rats. Anesthesia and Analgesia. 107: 1884-91. PMID 19020134 DOI: 10.1213/Ane.0B013E3181884Bbf  0.394
2007 Guo Z, Xia Z, Yuen VG, McNeill JH. Cardiac expression of adiponectin and its receptors in streptozotocin-induced diabetic rats. Metabolism: Clinical and Experimental. 56: 1363-71. PMID 17884446 DOI: 10.1016/J.Metabol.2007.05.005  0.385
2007 Liu KX, Rinne T, He W, Wang F, Xia Z. Propofol attenuates intestinal mucosa injury induced by intestinal ischemia-reperfusion in the rat. Canadian Journal of Anaesthesia = Journal Canadien D'Anesthã©Sie. 54: 366-74. PMID 17470888 DOI: 10.1007/Bf03022659  0.389
2007 Cai J, Yi FF, Yang XC, Lin GS, Jiang H, Wang T, Xia Z. Transplantation of embryonic stem cell-derived cardiomyocytes improves cardiac function in infarcted rat hearts. Cytotherapy. 9: 283-91. PMID 17464760 DOI: 10.1080/14653240701247838  0.336
2007 Xia Z, Kuo KH, Nagareddy PR, Wang F, Guo Z, Guo T, Jiang J, McNeill JH. N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats. Cardiovascular Research. 73: 770-82. PMID 17250813 DOI: 10.1016/J.Cardiores.2006.11.033  0.405
2007 Xia ZY, Wang XY, Chen X, Xia Z. Effect of NO donor sodium nitroprusside on lipopolysaccharide induced acute lung injury in rats. Injury. 38: 53-9. PMID 17141778 DOI: 10.1016/J.Injury.2006.09.021  0.332
2007 Guo Z, Xia Z, Jiang J, McNeill JH. Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine. American Journal of Physiology. Heart and Circulatory Physiology. 292: H1728-36. PMID 17122189 DOI: 10.1152/Ajpheart.01328.2005  0.41
2007 Xia Z, Liu M, McNeill JH. Increased PTEN mRNA Expression And Phosphorylation In The Myocardium Of Streptozotocin-Induced Diabetic Rats: Effects of N-Acetylcysteine The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A435-C  0.349
2006 Xia Z, Liu M, Wu Y, Sharma V, Luo T, Ouyang J, McNeill JH. N-acetylcysteine attenuates TNF-α-induced human vascular endothelial cell apoptosis and restores eNOS expression European Journal of Pharmacology. 550: 134-142. PMID 17026986 DOI: 10.1016/J.Ejphar.2006.08.044  0.316
2006 Xia Z, Guo Z, Nagareddy PR, Yuen V, Yeung E, McNeill JH. Antioxidant N-acetylcysteine restores myocardial Mn-SOD activity and attenuates myocardial dysfunction in diabetic rats. European Journal of Pharmacology. 544: 118-125. PMID 16859669 DOI: 10.1016/J.Ejphar.2006.06.033  0.421
2006 Luo T, Xia Z. A small dose of hydrogen peroxide enhances tumor necrosis factor-alpha toxicity in inducing human vascular endothelial cell apoptosis: Reversal with propofol Anesthesia and Analgesia. 103: 110-116. PMID 16790636 DOI: 10.1213/01.Ane.0000221183.02244.80  0.311
2006 Nagareddy PR, Xia Z, MacLeod KM, McNeill JH. N-acetylcysteine prevents nitrosative stress-associated depression of blood pressure and heart rate in streptozotocin diabetic rats. Journal of Cardiovascular Pharmacology. 47: 513-20. PMID 16680064 DOI: 10.1097/01.Fjc.0000211744.93701.25  0.381
2006 Xia Z, Wang F, Luo T. Effectiveness of isoflurane in inducing delayed preconditioning against myocardial infarction in vivo. Anesthesiology. 104: 383-384. PMID 16436872 DOI: 10.1097/00000542-200602000-00039  0.345
2006 Xia Z, Nagareddy PR, Guo Z, Zhang W, McNeill JH. Antioxidant N-acetylcysteine restores systemic nitric oxide availability and corrects depressions in arterial blood pressure and heart rate in diabetic rats. Free Radical Research. 40: 175-84. PMID 16390827 DOI: 10.1080/10715760500484336  0.393
2005 Cheng X, Xia Z, Leo JM, Pang CC. The effect of N-acetylcysteine on cardiac contractility to dobutamine in rats with streptozotocin-induced diabetes. European Journal of Pharmacology. 519: 118-26. PMID 16111676 DOI: 10.1016/J.Ejphar.2005.06.037  0.416
2005 Xia Z, Liu X, Zhan L, He Y, Luo T, Xia Z. Ginsenosides compound (shen-fu) attenuates gastrointestinal injury and inhibits inflammatory response after cardiopulmonary bypass in patients with congenital heart disease. The Journal of Thoracic and Cardiovascular Surgery. 130: 258-264. PMID 16077384 DOI: 10.1016/J.Jtcvs.2005.02.046  0.363
2005 Nagareddy PR, Xia Z, McNeill JH, MacLeod KM. Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes. American Journal of Physiology. Heart and Circulatory Physiology. 289: H2144-52. PMID 16006542 DOI: 10.1152/Ajpheart.00591.2005  0.36
2005 Luo T, Xia Z, Ansley DM, Ouyang J, Granville DJ, Li Y, Xia ZY, Zhou QS, Liu XY. Propofol dose-dependently reduces tumor necrosis factor-alpha-Induced human umbilical vein endothelial cell apoptosis: effects on Bcl-2 and Bax expression and nitric oxide generation. Anesthesia and Analgesia. 100: 1653-9. PMID 15920191 DOI: 10.1213/01.Ane.0000150945.95254.D8  0.31
2005 Xia Z, Kuo KH, McNeill JH, Ansley DM. Endothelin A and B receptor antagonist bosentan reduces postischemic myocardial injury in the rat: critical timing of administration. Canadian Journal of Physiology and Pharmacology. 83: 259-66. PMID 15870840 DOI: 10.1139/Y05-014  0.416
2005 Xia Z, Luo T, Wang F, Liu M, Xia Z, Ansley DM. Propofol and nitric oxide in TNF-alpha induced human ECV304 apoptosis Canadian Journal of Anaesthesia-Journal Canadien D Anesthesie. 52. DOI: 10.1007/Bf03023249  0.362
2004 Xia Z, Xia R, Lan HT, Luo T, Tang QZ, Xia ZY, Liu XY. Systemic ischemic preconditioning plus hemodilution enhanced early functional recovery of reperfused heart in the rabbits. Interactive Cardiovascular and Thoracic Surgery. 3: 528-32. PMID 17670302 DOI: 10.1016/J.Icvts.2004.05.007  0.341
2004 Xia Z, Godin DV, Ansley DM. Application of high-dose propofol during ischemia improves postischemic function of rat hearts: effects on tissue antioxidant capacity Canadian Journal of Physiology and Pharmacology. 82: 919-926. PMID 15573153 DOI: 10.1139/Y04-097  0.391
2004 Ansley DM, Xia Z. Anesthetic Preconditioning Versus Anesthetic Treatment: Effects on Ischemic Injury in Isolated Hearts Anesthesiology. 100: 1327-1328. PMID 15114246 DOI: 10.1097/00000542-200405000-00052  0.347
2003 Xia Z, Gu J, Ansley DM, Xia F, Yu J. Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. The Journal of Thoracic and Cardiovascular Surgery. 126: 1404-10. PMID 14666012 DOI: 10.1016/S0022-5223(03)00970-X  0.3
2003 Ansley DM, Xia Z, Dhaliwal BS. The relationship between plasma free 15-F2t-isoprostane concentration and early postoperative cardiac depression following warm heart surgery The Journal of Thoracic and Cardiovascular Surgery. 126: 1222-1223. PMID 14566285 DOI: 10.1016/S0022-5223(03)00794-3  0.323
2003 Xia Z, Godin DV, Ansley DM. Propofol enhances ischemic tolerance of middle-aged rat hearts: effects on 15-F2t-isoprostane formation and tissue antioxidant capacity Cardiovascular Research. 59: 113-121. PMID 12829182 DOI: 10.1016/S0008-6363(03)00351-1  0.314
2003 Xia Z, Godin DV, Chang TKH, Ansley DM. Dose-dependent protection of cardiac function by propofol during ischemia and early reperfusion in rats: effects on 15-F2t-isoprostane formation Canadian Journal of Physiology and Pharmacology. 81: 14-21. PMID 12665253 DOI: 10.1139/Y02-170  0.353
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