| Year |
Citation |
Score |
| 2020 |
Greenwood TA, Swerdlow NR, Sprock J, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Lazzeroni LC, Light GA, Nuechterlein KH, Radant AD, Silverman JM, Stone WS, Sugar CA, et al. Heritability of acoustic startle magnitude and latency from the consortium on the genetics of schizophrenia. Schizophrenia Research. PMID 33189519 DOI: 10.1016/j.schres.2020.11.003 |
0.309 |
|
| 2020 |
Freedman R, Olsen-Dufour AM, Olincy A. P50 inhibitory sensory gating in schizophrenia: analysis of recent studies. Schizophrenia Research. PMID 32061454 DOI: 10.1016/J.Schres.2020.02.003 |
0.431 |
|
| 2020 |
Kantrowitz JT, Javitt DC, Freedman R, Sehatpour P, Kegeles LS, Carlson M, Sobeih T, Wall MM, Choo TH, Vail B, Grinband J, Lieberman JA. Double blind, two dose, randomized, placebo-controlled, cross-over clinical trial of the positive allosteric modulator at the alpha7 nicotinic cholinergic receptor AVL-3288 in schizophrenia patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32015461 DOI: 10.1038/S41386-020-0628-9 |
0.425 |
|
| 2019 |
Greenwood TA, Lazzeroni LC, Maihofer AX, Swerdlow NR, Calkins ME, Freedman R, Green MF, Light GA, Nievergelt CM, Nuechterlein KH, Radant AD, Siever LJ, Silverman JM, Stone WS, Sugar CA, et al. Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Jama Psychiatry. PMID 31596458 DOI: 10.1001/Jamapsychiatry.2019.2850 |
0.427 |
|
| 2019 |
Leonard S, Mexal S, Freedman R. Smoking, Genetics and Schizophrenia: Evidence for Self Medication. Journal of Dual Diagnosis. 3: 43-59. PMID 19122786 DOI: 10.1300/J374V03N03_05 |
0.442 |
|
| 2019 |
Freedman R. 33.4 ETHICAL CONSIDERATIONS IN PRENATAL NUTRITIONAL INTERVENTIONS FOR SCHIZOPHRENIA Schizophrenia Bulletin. 45: S144-S144. DOI: 10.1093/Schbul/Sbz022.140 |
0.366 |
|
| 2019 |
Tregellas J, Harris J, Freedman R. 235. Hippocampal Hyperactivity in Schizophrenia, Relationship to Cognitive Deficits, and Potential as a Target for Therapeutic Development Biological Psychiatry. 85: S97-S98. DOI: 10.1016/J.Biopsych.2019.03.249 |
0.637 |
|
| 2018 |
Freedman R, Hunter SK, Hoffman MC. Prenatal Primary Prevention of Mental Illness by Micronutrient Supplements in Pregnancy. The American Journal of Psychiatry. appiajp201817070836. PMID 29558816 DOI: 10.1176/Appi.Ajp.2018.17070836 |
0.335 |
|
| 2018 |
Wong DF, Kuwabara H, Horti AG, Roberts JM, Nandi A, Casella N, Brasic J, Weerts EM, Kitzmiller K, Phan JA, Gapasin L, Sawa A, Valentine H, Wand G, George N, ... ... Freedman R, et al. PET Brain imaging of α7-nAChR with [18F]ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia. The International Journal of Neuropsychopharmacology. PMID 29522184 DOI: 10.1093/Ijnp/Pyy021 |
0.35 |
|
| 2018 |
Rahman A, Freedman R, Hollander E. S59. Alpha-7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator Galantamine in Autism Spectrum Disorder Biological Psychiatry. 83: S369-S370. DOI: 10.1016/J.Biopsych.2018.02.950 |
0.308 |
|
| 2018 |
Greenwood T, Lazzeroni L, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Light G, Nuechterlein K, Olincy A, Radant A, Seidman L, Siever L, Silverman J, Stone W, et al. S209. Genome-Wide Association of Endophenotypes for Schizophrenia From the Consortium On the Genetics of Schizophrenia (COGS) Study Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.1101 |
0.407 |
|
| 2017 |
Lewis AS, Olincy A, Buchanan RW, Kem WR, Picciotto MR, Freedman R. Effects of a nicotinic agonist on the Brief Psychiatric Rating Scale five-factor subscale model in schizophrenia. Schizophrenia Research. PMID 29050790 DOI: 10.1016/J.Schres.2017.10.016 |
0.409 |
|
| 2017 |
Kem WR, Olincy A, Johnson L, Harris J, Wagner BD, Buchanan RW, Christians U, Freedman R. Pharmacokinetic Limitations on Effects of an Alpha7 Nicotinic Receptor Agonist in Schizophrenia: Randomized Trial with an Extended Release Formulation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28825423 DOI: 10.1038/Npp.2017.182 |
0.383 |
|
| 2017 |
Gee KW, Olincy A, Kanner R, Johnson L, Hogenkamp D, Harris J, Tran M, Edmonds SA, Sauer W, Yoshimura R, Johnstone T, Freedman R. First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. Journal of Psychopharmacology (Oxford, England). 269881117691590. PMID 28196430 DOI: 10.1177/0269881117691590 |
0.361 |
|
| 2017 |
Freedman R. Endophenotypes in schizophrenia European Neuropsychopharmacology. 27. DOI: 10.1016/S0924-977X(17)30986-0 |
0.422 |
|
| 2016 |
Olincy A, Blakeley-Smith A, Johnson L, Kem WR, Freedman R. Brief Report: Initial Trial of Alpha7-Nicotinic Receptor Stimulation in Two Adult Patients with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. PMID 27565651 DOI: 10.1007/S10803-016-2890-6 |
0.388 |
|
| 2016 |
Millard SP, Shofer J, Braff D, Calkins M, Cadenhead K, Freedman R, Green MF, Greenwood TA, Gur R, Gur R, Lazzeroni LC, Light GA, Olincy A, Nuechterlein K, Seidman L, et al. Prioritizing schizophrenia endophenotypes for future genetic studies: An example using data from the COGS-1 family study. Schizophrenia Research. PMID 27132484 DOI: 10.1016/J.Schres.2016.04.011 |
0.393 |
|
| 2015 |
Greenwood TA, Lazzeroni LC, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, et al. Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study. Schizophrenia Research. PMID 26597662 DOI: 10.1016/J.Schres.2015.11.008 |
0.393 |
|
| 2015 |
Freedman R. Molecules and psychiatry. The American Journal of Psychiatry. 172: 1051. PMID 26575442 DOI: 10.1176/Appi.Ajp.2015.15091219 |
0.307 |
|
| 2015 |
Greenwood TA, Light GA, Swerdlow NR, Calkins ME, Green MF, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, ... ... Freedman R, et al. Gating Deficit Heritability and Correlation With Increased Clinical Severity in Schizophrenia Patients With Positive Family History. The American Journal of Psychiatry. appiajp201515050605. PMID 26441157 DOI: 10.1176/Appi.Ajp.2015.15050605 |
0.36 |
|
| 2015 |
Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, ... ... Freedman R, et al. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology. PMID 26286434 DOI: 10.1093/Ije/Dyv136 |
0.355 |
|
| 2015 |
Freedman R, Ross RG. Prenatal choline and the development of schizophrenia. Shanghai Archives of Psychiatry. 27: 90-102. PMID 26120259 DOI: 10.11919/J.Issn.1002-0829.215006 |
0.432 |
|
| 2015 |
Ross RG, Freedman R. Endophenotypes in Schizophrenia for the Perinatal Period: Criteria for Validation. Schizophrenia Bulletin. 41: 824-34. PMID 25943124 DOI: 10.1093/Schbul/Sbv054 |
0.41 |
|
| 2015 |
Sinkus ML, Graw S, Freedman R, Ross RG, Lester HA, Leonard S. The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function. Neuropharmacology. 96: 274-88. PMID 25701707 DOI: 10.1016/J.Neuropharm.2015.02.006 |
0.335 |
|
| 2015 |
Wu WL, Adams CE, Stevens KE, Chow KH, Freedman R, Patterson PH. The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring. Brain, Behavior, and Immunity. 46: 192-202. PMID 25683697 DOI: 10.1016/J.Bbi.2015.02.005 |
0.359 |
|
| 2015 |
Seidman LJ, Hellemann G, Nuechterlein KH, Greenwood TA, Braff DL, Cadenhead KS, Calkins ME, Freedman R, Gur RE, Gur RC, Lazzeroni LC, Light GA, Olincy A, Radant AD, Siever LJ, et al. Factor structure and heritability of endophenotypes in schizophrenia: findings from the Consortium on the Genetics of Schizophrenia (COGS-1). Schizophrenia Research. 163: 73-9. PMID 25682549 DOI: 10.1016/J.Schres.2015.01.027 |
0.408 |
|
| 2015 |
Radant AD, Millard SP, Braff DL, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Meichle SP, Nuechterlein KH, Olincy A, et al. Robust differences in antisaccade performance exist between COGS schizophrenia cases and controls regardless of recruitment strategies. Schizophrenia Research. 163: 47-52. PMID 25553977 DOI: 10.1016/J.Schres.2014.12.016 |
0.432 |
|
| 2015 |
Javitt DC, Freedman R. Sensory processing dysfunction in the personal experience and neuronal machinery of schizophrenia. The American Journal of Psychiatry. 172: 17-31. PMID 25553496 DOI: 10.1176/Appi.Ajp.2014.13121691 |
0.439 |
|
| 2015 |
Stone WS, Mesholam-Gately RI, Braff DL, Calkins ME, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Siever LJ, et al. California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: comparing the first and second phases of the Consortium on the Genetics of Schizophrenia (COGS). Schizophrenia Research. 163: 32-7. PMID 25497440 DOI: 10.1016/J.Schres.2014.10.029 |
0.342 |
|
| 2015 |
Gur RC, Braff DL, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Lazzeroni LC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, et al. Neurocognitive performance in family-based and case-control studies of schizophrenia. Schizophrenia Research. 163: 17-23. PMID 25432636 DOI: 10.1016/J.Schres.2014.10.049 |
0.377 |
|
| 2014 |
Wang Y, Xiao C, Indersmitten T, Freedman R, Leonard S, Lester HA. The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7. The Journal of Biological Chemistry. 289: 26451-63. PMID 25056953 DOI: 10.1074/Jbc.M114.582858 |
0.333 |
|
| 2014 |
Marder SR, Freedman R. Learning from people with schizophrenia Schizophrenia Bulletin. 40: 1185-1186. PMID 24973131 DOI: 10.1093/Schbul/Sbu096 |
0.385 |
|
| 2014 |
Schmeidler J, Lazzeroni LC, Swerdlow NR, Ferreira RP, Braff DL, Calkins ME, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Olincy A, Nuechterlein KH, et al. Paternal age of schizophrenia probands and endophenotypic differences from unaffected siblings. Psychiatry Research. 219: 67-71. PMID 24913833 DOI: 10.1016/J.Psychres.2014.05.035 |
0.38 |
|
| 2014 |
Light G, Greenwood TA, Swerdlow NR, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, et al. Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study. Schizophrenia Bulletin. 40: 1404-11. PMID 24903414 DOI: 10.1093/Schbul/Sbu064 |
0.383 |
|
| 2014 |
Tsuang D, Esterberg M, Braff D, Calkins M, Cadenhead K, Dobie D, Freedman R, Green MF, Greenwood T, Gur R, Gur R, Horan W, Lazzeroni LC, Light GA, Millard SP, et al. Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia? Plos One. 9: e88379. PMID 24523888 DOI: 10.1371/Journal.Pone.0088379 |
0.407 |
|
| 2014 |
Tregellas JR, Smucny J, Harris JG, Olincy A, Maharajh K, Kronberg E, Eichman LC, Lyons E, Freedman R. Intrinsic hippocampal activity as a biomarker for cognition and symptoms in schizophrenia. The American Journal of Psychiatry. 171: 549-56. PMID 24435071 DOI: 10.1176/Appi.Ajp.2013.13070981 |
0.649 |
|
| 2014 |
Freedman R. α7-nicotinic acetylcholine receptor agonists for cognitive enhancement in schizophrenia. Annual Review of Medicine. 65: 245-61. PMID 24111888 DOI: 10.1146/Annurev-Med-092112-142937 |
0.44 |
|
| 2013 |
Sinkus ML, Adams CE, Logel J, Freedman R, Leonard S. Expression of immune genes on chromosome 6p21.3-22.1 in schizophrenia. Brain, Behavior, and Immunity. 32: 51-62. PMID 23395714 DOI: 10.1016/J.Bbi.2013.01.087 |
0.409 |
|
| 2013 |
Calkins ME, Ray A, Gur RC, Freedman R, Green MF, Greenwood TA, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar C, et al. Sex differences in familiality effects on neurocognitive performance in schizophrenia. Biological Psychiatry. 73: 976-84. PMID 23395246 DOI: 10.1016/J.Biopsych.2012.12.021 |
0.389 |
|
| 2013 |
Ross RG, Hunter SK, McCarthy L, Beuler J, Hutchison AK, Wagner BD, Leonard S, Stevens KE, Freedman R. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. The American Journal of Psychiatry. 170: 290-8. PMID 23318559 DOI: 10.1176/Appi.Ajp.2012.12070940 |
0.39 |
|
| 2012 |
Fanous AH, Zhou B, Aggen SH, Bergen SE, Amdur RL, Duan J, Sanders AR, Shi J, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, ... ... Freedman R, et al. Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms. The American Journal of Psychiatry. 169: 1309-17. PMID 23212062 DOI: 10.1176/Appi.Ajp.2012.12020218 |
0.38 |
|
| 2012 |
Freedman R. Brain development and schizophrenia. The American Journal of Psychiatry. 169: 1019-21. PMID 23032379 DOI: 10.1176/Appi.Ajp.2012.12081017 |
0.397 |
|
| 2012 |
Olincy A, Freedman R. Nicotinic mechanisms in the treatment of psychotic disorders: a focus on the α7 nicotinic receptor. Handbook of Experimental Pharmacology. 211-32. PMID 23027417 DOI: 10.1007/978-3-642-25758-2_8 |
0.446 |
|
| 2012 |
Stephens SH, Franks A, Berger R, Palionyte M, Fingerlin TE, Wagner B, Logel J, Olincy A, Ross RG, Freedman R, Leonard S. Multiple genes in the 15q13-q14 chromosomal region are associated with schizophrenia. Psychiatric Genetics. 22: 1-14. PMID 21970977 DOI: 10.1097/Ypg.0B013E32834C0C33 |
0.319 |
|
| 2011 |
Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St. Clair D, Corvin A, Gurling H, ... ... Freedman R, et al. Genome-wide association study identifies five new schizophrenia loci Nature Genetics. 43: 969-978. PMID 21926974 DOI: 10.1038/Ng.940 |
0.349 |
|
| 2011 |
Greenwood TA, Lazzeroni LC, Murray SS, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Gur RE, Gur RC, Hardiman G, Kelsoe JR, Leonard S, Light GA, Nuechterlein KH, Olincy A, ... ... Freedman R, et al. Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. The American Journal of Psychiatry. 168: 930-46. PMID 21498463 DOI: 10.1176/Appi.Ajp.2011.10050723 |
0.398 |
|
| 2011 |
Miwa JM, Freedman R, Lester HA. Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses. Neuron. 70: 20-33. PMID 21482353 DOI: 10.1016/J.Neuron.2011.03.014 |
0.362 |
|
| 2011 |
Stone WS, Giuliano AJ, Tsuang MT, Braff DL, Cadenhead KS, Calkins ME, Dobie DJ, Faraone SV, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, et al. Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS). Schizophrenia Research. 128: 102-10. PMID 21288694 DOI: 10.1016/J.Schres.2011.01.005 |
0.415 |
|
| 2011 |
Levinson DF, Duan J, Oh S, Wang K, Sanders AR, Shi J, Zhang N, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, ... ... Freedman R, et al. Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. The American Journal of Psychiatry. 168: 302-16. PMID 21285140 DOI: 10.1176/Appi.Ajp.2010.10060876 |
0.405 |
|
| 2011 |
Tregellas JR, Tanabe J, Rojas DC, Shatti S, Olincy A, Johnson L, Martin LF, Soti F, Kem WR, Leonard S, Freedman R. Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia. Biological Psychiatry. 69: 7-11. PMID 20728875 DOI: 10.1016/J.Biopsych.2010.07.004 |
0.668 |
|
| 2011 |
Hunter SK, Kisley MA, McCarthy L, Freedman R, Ross RG. Diminished cerebral inhibition in neonates associated with risk factors for schizophrenia: parental psychosis, maternal depression, and nicotine use. Schizophrenia Bulletin. 37: 1200-8. PMID 20403924 DOI: 10.1093/Schbul/Sbq036 |
0.32 |
|
| 2010 |
Olincy A, Braff DL, Adler LE, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, ... ... Freedman R, et al. Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophrenia Research. 119: 175-82. PMID 20382002 DOI: 10.1016/J.Schres.2010.03.004 |
0.45 |
|
| 2010 |
Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Meichle SP, Millard SP, Mintz J, et al. Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study. Psychophysiology. 47: 846-56. PMID 20374545 DOI: 10.1111/J.1469-8986.2010.01004.X |
0.421 |
|
| 2010 |
Freedman R. Psychiatrists' role in the health of the pregnant mother and the risk for schizophrenia in her offspring. The American Journal of Psychiatry. 167: 239-40. PMID 20194483 DOI: 10.1176/Appi.Ajp.2009.09121755 |
0.359 |
|
| 2010 |
Tregellas JR, Olincy A, Johnson L, Tanabe J, Shatti S, Martin LF, Singel D, Du YP, Soti F, Kem WR, Freedman R. Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 938-42. PMID 19956085 DOI: 10.1038/Npp.2009.196 |
0.673 |
|
| 2010 |
Ross RG, Stevens KE, Proctor WR, Leonard S, Kisley MA, Hunter SK, Freedman R, Adams CE. Research review: Cholinergic mechanisms, early brain development, and risk for schizophrenia. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 51: 535-49. PMID 19925602 DOI: 10.1111/J.1469-7610.2009.02187.X |
0.43 |
|
| 2010 |
Freedman R, Goldowitz D. Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia. Progress in Neurobiology. 90: 263-75. PMID 19853005 DOI: 10.1016/J.Pneurobio.2009.10.008 |
0.444 |
|
| 2010 |
Mexal S, Berger R, Logel J, Ross RG, Freedman R, Leonard S. Differential regulation of alpha7 nicotinic receptor gene (CHRNA7) expression in schizophrenic smokers. Journal of Molecular Neuroscience : Mn. 40: 185-95. PMID 19680823 DOI: 10.1007/S12031-009-9233-4 |
0.344 |
|
| 2009 |
Sinkus ML, Lee MJ, Gault J, Logel J, Short M, Freedman R, Christian SL, Lyon J, Leonard S. A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia. Brain Research. 1291: 1-11. PMID 19631623 DOI: 10.1016/J.Brainres.2009.07.041 |
0.383 |
|
| 2009 |
Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I, Dudbridge F, Holmans PA, Whittemore AS, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, ... ... Freedman R, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature. 460: 753-7. PMID 19571809 DOI: 10.1038/Nature08192 |
0.401 |
|
| 2009 |
Hodge SE, Freedman R. Zeroing in on a schizophrenia gene: a new tool to assess the probability. The American Journal of Psychiatry. 166: 392-4. PMID 19339362 DOI: 10.1176/Appi.Ajp.2009.09010006 |
0.373 |
|
| 2009 |
Stephens SH, Logel J, Barton A, Franks A, Schultz J, Short M, Dickenson J, James B, Fingerlin TE, Wagner B, Hodgkinson C, Graw S, Ross RG, Freedman R, Leonard S. Association of the 5'-upstream regulatory region of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) with schizophrenia. Schizophrenia Research. 109: 102-12. PMID 19181484 DOI: 10.1016/J.Schres.2008.12.017 |
0.45 |
|
| 2008 |
Turetsky BI, Greenwood TA, Olincy A, Radant AD, Braff DL, Cadenhead KS, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Schork NJ, et al. Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands. Biological Psychiatry. 64: 1051-9. PMID 18701089 DOI: 10.1016/J.Biopsych.2008.06.018 |
0.437 |
|
| 2008 |
Simosky JK, Freedman R, Stevens KE. Olanzapine improves deficient sensory inhibition in DBA/2 mice. Brain Research. 1233: 129-36. PMID 18687314 DOI: 10.1016/J.Brainres.2008.07.057 |
0.798 |
|
| 2008 |
O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, ... ... Freedman R, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nature Genetics. 40: 1053-5. PMID 18677311 DOI: 10.1038/Ng.201 |
0.332 |
|
| 2008 |
Horan WP, Braff DL, Nuechterlein KH, Sugar CA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Olincy A, Radant AD, et al. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophrenia Research. 103: 218-28. PMID 18406578 DOI: 10.1016/J.Schres.2008.02.014 |
0.415 |
|
| 2008 |
Freedman R. Cannabis, inhibitory neurons, and the progressive course of schizophrenia. The American Journal of Psychiatry. 165: 416-9. PMID 18381910 DOI: 10.1176/Appi.Ajp.2008.08010147 |
0.409 |
|
| 2008 |
Freedman R, Olincy A, Buchanan RW, Harris JG, Gold JM, Johnson L, Allensworth D, Guzman-Bonilla A, Clement B, Ball MP, Kutnick J, Pender V, Martin LF, Stevens KE, Wagner BD, et al. Initial phase 2 trial of a nicotinic agonist in schizophrenia. The American Journal of Psychiatry. 165: 1040-7. PMID 18381905 DOI: 10.1176/Appi.Ajp.2008.07071135 |
0.425 |
|
| 2008 |
Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, Burrell GJ, Rice JP, Nertney DA, Olincy A, Rozic P, Vinogradov S, Buccola NG, Mowry BJ, Freedman R, et al. No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. The American Journal of Psychiatry. 165: 497-506. PMID 18198266 DOI: 10.1176/Appi.Ajp.2007.07101573 |
0.324 |
|
| 2008 |
Mexal S, Berger R, Pearce L, Barton A, Logel J, Adams CE, Ross RG, Freedman R, Leonard S. Regulation of a novel alphaN-catenin splice variant in schizophrenic smokers. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 759-68. PMID 18163523 DOI: 10.1002/Ajmg.B.30679 |
0.311 |
|
| 2008 |
Tanabe J, Crowley T, Hutchison K, Miller D, Johnson G, Du YP, Zerbe G, Freedman R. Ventral striatal blood flow is altered by acute nicotine but not withdrawal from nicotine Neuropsychopharmacology. 33: 627-633. PMID 17460613 DOI: 10.1038/Sj.Npp.1301428 |
0.318 |
|
| 2008 |
Tregellas JR, Freedman R. Nicotinic cholinergic cortical dysfunction in schizophrenia Cortical Deficits in Schizophrenia: From Genes to Function. 97-111. DOI: 10.1007/978-0-387-74351-6_5 |
0.636 |
|
| 2007 |
Martin LF, Hall MH, Ross RG, Zerbe G, Freedman R, Olincy A. Physiology of schizophrenia, bipolar disorder, and schizoaffective disorder American Journal of Psychiatry. 164: 1900-1906. PMID 18056246 DOI: 10.1176/Appi.Ajp.2007.06010017 |
0.398 |
|
| 2007 |
Greenwood TA, Braff DL, Light GA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, et al. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Archives of General Psychiatry. 64: 1242-50. PMID 17984393 DOI: 10.1001/Archpsyc.64.11.1242 |
0.414 |
|
| 2007 |
Freedman R. Exacerbation of schizophrenia by varenicline. The American Journal of Psychiatry. 164: 1269. PMID 17671295 DOI: 10.1176/Appi.Ajp.2007.07020326 |
0.325 |
|
| 2007 |
Buchanan RW, Freedman R, Javitt DC, Abi-Dargham A, Lieberman JA. Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia. Schizophrenia Bulletin. 33: 1120-30. PMID 17641146 DOI: 10.1093/Schbul/Sbm083 |
0.365 |
|
| 2007 |
Martin LF, Freedman R. Schizophrenia and the α7 Nicotinic Acetylcholine Receptor International Review of Neurobiology. 78: 225-246. PMID 17349863 DOI: 10.1016/S0074-7742(06)78008-4 |
0.456 |
|
| 2007 |
Swerdlow NR, Sprock J, Light GA, Cadenhead K, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Mintz J, Olincy A, Nuechterlein KH, Radant AD, Schork NJ, et al. Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophrenia Research. 92: 237-51. PMID 17346930 DOI: 10.1016/J.Schres.2007.01.012 |
0.339 |
|
| 2007 |
Tregellas JR, Davalos DB, Rojas DC, Waldo MC, Gibson L, Wylie K, Du YP, Freedman R. Increased hemodynamic response in the hippocampus, thalamus and prefrontal cortex during abnormal sensory gating in schizophrenia. Schizophrenia Research. 92: 262-72. PMID 17336502 DOI: 10.1016/J.Schres.2006.12.033 |
0.678 |
|
| 2007 |
Freedman R. Neuronal dysfunction and schizophrenia symptoms. The American Journal of Psychiatry. 164: 385-90. PMID 17329460 DOI: 10.1176/Ajp.2007.164.3.385 |
0.392 |
|
| 2007 |
Martin LF, Leonard S, Hall MH, Tregellas JR, Freedman R, Olincy A. Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 611-4. PMID 17192894 DOI: 10.1002/Ajmg.B.30470 |
0.645 |
|
| 2007 |
Freedman R, Carpenter WT, Davis JM, Goldman HH, Tamminga CA, Thomas M. The costs of drugs for schizophrenia. The American Journal of Psychiatry. 163: 2029-31. PMID 17151146 DOI: 10.1176/ajp.2006.163.12.2029 |
0.365 |
|
| 2007 |
Braff DL, Freedman R, Schork NJ, Gottesman II. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophrenia Bulletin. 33: 21-32. PMID 17088422 DOI: 10.1093/Schbul/Sbl049 |
0.427 |
|
| 2007 |
Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, et al. The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophrenia Bulletin. 33: 33-48. PMID 17035358 DOI: 10.1093/Schbul/Sbl044 |
0.376 |
|
| 2007 |
Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Light GA, Meichle SP, Mintz J, Nuechterlein KH, Schork NJ, et al. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophrenia Research. 89: 320-9. PMID 17023145 DOI: 10.1016/J.Schres.2006.08.010 |
0.408 |
|
| 2006 |
Mexal S, Berger R, Adams CE, Ross RG, Freedman R, Leonard S. Brain pH has a significant impact on human postmortem hippocampal gene expression profiles Brain Research. 1106: 1-11. PMID 16843448 DOI: 10.1016/J.Brainres.2006.05.043 |
0.323 |
|
| 2006 |
Leonard S, Freedman R. Genetics of chromosome 15q13-q14 in schizophrenia. Biological Psychiatry. 60: 115-22. PMID 16843094 DOI: 10.1016/J.Biopsych.2006.03.054 |
0.392 |
|
| 2006 |
Olincy A, Harris JG, Johnson LL, Pender V, Kongs S, Allensworth D, Ellis J, Zerbe GO, Leonard S, Stevens KE, Stevens JO, Martin L, Adler LE, Soti F, Kem WR, ... Freedman R, et al. Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Archives of General Psychiatry. 63: 630-8. PMID 16754836 DOI: 10.1001/Archpsyc.63.6.630 |
0.463 |
|
| 2006 |
Freedman R, Leonard S, Waldo M, Gault J, Olincy A, Adler LE. Characterization of allelic variants at chromosome 15q14 in schizophrenia Genes, Brain and Behavior. 5: 14-22. PMID 16417613 DOI: 10.1111/J.1601-183X.2006.00190.X |
0.376 |
|
| 2006 |
Tanabe J, Tregellas JR, Martin LF, Freedman R. Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia. Biological Psychiatry. 59: 754-61. PMID 16259965 DOI: 10.1016/J.Biopsych.2005.09.004 |
0.638 |
|
| 2005 |
Davalos DB, Kisley MA, Freedman R. Behavioral and electrophysiological indices of temporal processing dysfunction in schizophrenia. The Journal of Neuropsychiatry and Clinical Neurosciences. 17: 517-25. PMID 16387992 DOI: 10.1176/Jnp.17.4.517 |
0.355 |
|
| 2005 |
Freedman R. The choice of antipsychotic drugs for schizophrenia. The New England Journal of Medicine. 353: 1286-8. PMID 16172204 DOI: 10.1056/Nejme058200 |
0.364 |
|
| 2005 |
Hashimoto K, Iyo M, Freedman R, Stevens KE. Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of alpha 7 nicotinic acetylcholine receptors. Psychopharmacology. 183: 13-9. PMID 16136299 DOI: 10.1007/S00213-005-0142-0 |
0.398 |
|
| 2005 |
Mexal S, Frank M, Berger R, Adams CE, Ross RG, Freedman R, Leonard S. Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers. Molecular Brain Research. 139: 317-332. PMID 16122832 DOI: 10.1016/J.Molbrainres.2005.06.006 |
0.319 |
|
| 2005 |
Freedman R, Ross R, Leonard S, Myles-Worsley M, Adams CE, Waldo M, Tregellas J, Martin L, Olincy A, Tanabe J, Kisley MA, Hunter S, Stevens KE. Early biomarkers of psychosis. Dialogues in Clinical Neuroscience. 7: 17-29. PMID 16060593 |
0.629 |
|
| 2005 |
Koike K, Hashimoto K, Takai N, Shimizu E, Komatsu N, Watanabe H, Nakazato M, Okamura N, Stevens KE, Freedman R, Iyo M. Tropisetron improves deficits in auditory P50 suppression in schizophrenia. Schizophrenia Research. 76: 67-72. PMID 15927799 DOI: 10.1016/J.Schres.2004.12.016 |
0.471 |
|
| 2005 |
Tregellas JR, Tanabe JL, Martin LF, Freedman R. FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia. The American Journal of Psychiatry. 162: 391-3. PMID 15677609 DOI: 10.1176/Appi.Ajp.162.2.391 |
0.656 |
|
| 2004 |
Adler LE, Olincy A, Cawthra EM, McRae KA, Harris JG, Nagamoto HT, Waldo MC, Hall MH, Bowles A, Woodward L, Ross RG, Freedman R. Varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients. The American Journal of Psychiatry. 161: 1822-8. PMID 15465979 DOI: 10.1176/Ajp.161.10.1822 |
0.438 |
|
| 2004 |
Martin LF, Kem WR, Freedman R. Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia Psychopharmacology. 174: 54-64. PMID 15205879 DOI: 10.1007/S00213-003-1750-1 |
0.458 |
|
| 2004 |
Harris JG, Kongs S, Allensworth D, Martin L, Tregellas J, Sullivan B, Zerbe G, Freedman R. Effects of nicotine on cognitive deficits in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1378-85. PMID 15138435 DOI: 10.1038/Sj.Npp.1300450 |
0.654 |
|
| 2004 |
Myles-Worsley M, Ord L, Blailes F, Ngiralmau H, Freedman R. P50 sensory gating in adolescents from a pacific island isolate with elevated risk for schizophrenia. Biological Psychiatry. 55: 663-7. PMID 15038993 DOI: 10.1016/J.Biopsych.2003.12.006 |
0.397 |
|
| 2004 |
Tregellas JR, Tanabe JL, Miller DE, Ross RG, Olincy A, Freedman R. Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study. The American Journal of Psychiatry. 161: 315-21. PMID 14754781 DOI: 10.1176/Appi.Ajp.161.2.315 |
0.645 |
|
| 2003 |
Freedman R. Schizophrenia. The New England Journal of Medicine. 349: 1738-49. PMID 14585943 DOI: 10.1056/NEJMra035458 |
0.308 |
|
| 2003 |
Gault J, Hopkins J, Berger R, Drebing C, Logel J, Walton C, Short M, Vianzon R, Olincy A, Ross RG, Adler LE, Freedman R, Leonard S. Comparison of polymorphisms in the alpha7 nicotinic receptor gene and its partial duplication in schizophrenic and control subjects. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 123: 39-49. PMID 14582144 DOI: 10.1002/Ajmg.B.20061 |
0.404 |
|
| 2003 |
Kisley MA, Olincy A, Robbins E, Polk SD, Adler LE, Waldo MC, Freedman R. Sensory gating impairment associated with schizophrenia persists into REM sleep. Psychophysiology. 40: 29-38. PMID 12751801 DOI: 10.1111/1469-8986.00004 |
0.346 |
|
| 2003 |
Kisley MA, Polk SD, Ross RG, Levisohn PM, Freedman R. Early postnatal development of sensory gating. Neuroreport. 14: 693-7. PMID 12692465 DOI: 10.1097/00001756-200304150-00007 |
0.342 |
|
| 2003 |
Freedman R, Olincy A, Ross RG, Waldo MC, Stevens KE, Adler LE, Leonard S. The genetics of sensory gating deficits in schizophrenia. Current Psychiatry Reports. 5: 155-61. PMID 12685995 DOI: 10.1007/S11920-003-0032-2 |
0.498 |
|
| 2003 |
Simosky JK, Stevens KE, Adler LE, Freedman R. Clozapine improves deficient inhibitory auditory processing in DBA/2 mice, via a nicotinic cholinergic mechanism. Psychopharmacology. 165: 386-96. PMID 12459928 DOI: 10.1007/S00213-002-1285-X |
0.812 |
|
| 2003 |
Davalos D, Kisley M, Ross R, Ellis J, Freedman R. Mismatch negativity and behavioral indices of auditory temporal processing in schizophrenia Schizophrenia Research. 60: 249-250. DOI: 10.1016/S0920-9964(03)81270-7 |
0.394 |
|
| 2003 |
Tregellas J, Tanabe J, Miller D, Ross R, Freedman R. FMRI of smooth pursuit eye movement abnormalities in schizophrenia Schizophrenia Research. 60: 235. DOI: 10.1016/S0920-9964(03)81231-8 |
0.639 |
|
| 2002 |
Simosky JK, Stevens KE, Freedman R. Nicotinic agonists and psychosis. Current Drug Targets. Cns and Neurological Disorders. 1: 149-62. PMID 12769624 DOI: 10.2174/1568007024606168 |
0.811 |
|
| 2002 |
Leonard S, Gault J, Hopkins J, Logel J, Vianzon R, Short M, Drebing C, Berger R, Venn D, Sirota P, Zerbe G, Olincy A, Ross RG, Adler LE, Freedman R. Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Archives of General Psychiatry. 59: 1085-96. PMID 12470124 DOI: 10.1001/Archpsyc.59.12.1085 |
0.441 |
|
| 2002 |
Ross RG, Olincy A, Mikulich SK, Radant AD, Harris JG, Waldo M, Compagnon N, Heinlein S, Leonard S, Zerbe GO, Adler L, Freedman R. Admixture analysis of smooth pursuit eye movements in probands with schizophrenia and their relatives suggests gain and leading saccades are potential endophenotypes. Psychophysiology. 39: 809-19. PMID 12462508 DOI: 10.1017/S0048577202011691 |
0.383 |
|
| 2002 |
Tanabe J, Tregellas J, Miller D, Ross RG, Freedman R. Brain activation during smooth-pursuit eye movements. Neuroimage. 17: 1315-24. PMID 12414271 DOI: 10.1006/Nimg.2002.1263 |
0.57 |
|
| 2002 |
Tregellas JR, Tanabe JL, Miller DE, Freedman R. Monitoring eye movements during fMRI tasks with echo planar images. Human Brain Mapping. 17: 237-43. PMID 12395391 DOI: 10.1002/Hbm.10070 |
0.556 |
|
| 2002 |
Harris JG, Young DA, Rojas DC, Cajade-Law A, Scherzinger A, Nawroz S, Adler LE, Cullum CM, Simon J, Freedman R. Increased hippocampal volume in schizophrenics' parents with ancestral history of schizophrenia. Schizophrenia Research. 55: 11-7. PMID 11955959 DOI: 10.1016/S0920-9964(01)00272-9 |
0.376 |
|
| 2002 |
Tanabe J, Miller D, Tregellas J, Freedman R, Meyer FG. Comparison of detrending methods for optimal fMRI preprocessing. Neuroimage. 15: 902-7. PMID 11906230 DOI: 10.1006/Nimg.2002.1053 |
0.541 |
|
| 2002 |
Freedman R, Adler LE, Olincy A, Waldo MC, Ross RG, Stevens KE, Leonard S. Input dysfunction, schizotypy, and genetic models of schizophrenia. Schizophrenia Research. 54: 25-32. PMID 11853975 DOI: 10.1016/S0920-9964(01)00348-6 |
0.45 |
|
| 2002 |
Freedman R, Leonard S. Genetic linkage to schizophrenia at chromosome 15q14. American Journal of Medical Genetics. 105: 655-7. PMID 11803510 DOI: 10.1002/Ajmg.1548 |
0.355 |
|
| 2001 |
Freedman R, Leonard S, Olincy A, Kaufmann CA, Malaspina D, Cloninger CR, Svrakic D, Faraone SV, Tsuang MT. Evidence for the multigenic inheritance of schizophrenia. American Journal of Medical Genetics. 105: 794-800. PMID 11803533 DOI: 10.1002/Ajmg.10100 |
0.405 |
|
| 2001 |
Leonard S, Adler LE, Benhammou K, Berger R, Breese CR, Drebing C, Gault J, Lee MJ, Logel J, Olincy A, Ross RG, Stevens K, Sullivan B, Vianzon R, Virnich DE, ... ... Freedman R, et al. Smoking and mental illness. Pharmacology, Biochemistry, and Behavior. 70: 561-70. PMID 11796154 DOI: 10.1016/S0091-3057(01)00677-3 |
0.425 |
|
| 2001 |
Adams CE, Stitzel JA, Collins AC, Freedman R. Alpha7-nicotinic receptor expression and the anatomical organization of hippocampal interneurons. Brain Research. 922: 180-90. PMID 11743948 DOI: 10.1016/S0006-8993(01)03115-8 |
0.304 |
|
| 2001 |
Simosky JK, Stevens KE, Kem WR, Freedman R. Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice. Biological Psychiatry. 50: 493-500. PMID 11600102 DOI: 10.1016/S0006-3223(01)01093-9 |
0.794 |
|
| 2001 |
Kisley MA, Olincy A, Freedman R. The effect of state on sensory gating: comparison of waking, REM and non-REM sleep. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 112: 1154-65. PMID 11516727 DOI: 10.1016/S1388-2457(01)00578-8 |
0.334 |
|
| 2001 |
Freedman R, Leonard S, Gault JM, Hopkins J, Cloninger CR, Kaufmann CA, Tsuang MT, Farone SV, Malaspina D, Svrakic DM, Sanders A, Gejman P. Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7). American Journal of Medical Genetics. 105: 20-2. PMID 11424985 DOI: 10.1002/1096-8628(20010108)105:1<20::Aid-Ajmg1047>3.0.Co;2-C |
0.43 |
|
| 2001 |
Adler LE, Olincy A, Cawthra E, Hoffer M, Nagamoto HT, Amass L, Freedman R. Reversal of diminished inhibitory sensory gating in cocaine addicts by a nicotinic cholinergic mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 671-9. PMID 11331147 DOI: 10.1016/S0893-133X(00)00242-6 |
0.334 |
|
| 2001 |
Freedman R, Adams CE, Leonard S. The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. Journal of Chemical Neuroanatomy. 20: 299-306. PMID 11207427 DOI: 10.1016/S0891-0618(00)00109-5 |
0.423 |
|
| 2001 |
Tregellas JR, Tanabe JL, Miller D, Freedman R. Activation and habituation during smooth pursuit eye movements as revealed by fMRI Neuroimage. 13: 1271. DOI: 10.1016/S1053-8119(01)92585-6 |
0.553 |
|
| 2000 |
Buervenich S, Carmine A, Arvidsson M, Xiang F, Zhang Z, Sydow O, Jönsson EG, Sedvall GC, Leonard S, Ross RG, Freedman R, Chowdari KV, Nimgaonkar VL, Perlmann T, Anvret M, et al. NURR1 mutations in cases of schizophrenia and manic-depressive disorder. American Journal of Medical Genetics. 96: 808-13. PMID 11121187 DOI: 10.1002/1096-8628(20001204)96:6<808::Aid-Ajmg23>3.0.Co;2-E |
0.323 |
|
| 2000 |
Adams CE, Stevens KE, Kem WR, Freedman R. Inhibition of nitric oxide synthase prevents alpha 7 nicotinic receptor-mediated restoration of inhibitory auditory gating in rat hippocampus. Brain Research. 877: 235-44. PMID 10986337 DOI: 10.1016/S0006-8993(00)02677-9 |
0.327 |
|
| 2000 |
Olincy A, Ross RG, Harris JG, Young DA, McAndrews MA, Cawthra E, McRae KA, Sullivan B, Adler LE, Freedman R. The P50 auditory event-evoked potential in adult attention-deficit disorder: comparison with schizophrenia. Biological Psychiatry. 47: 969-77. PMID 10838065 DOI: 10.1016/S0006-3223(00)00239-0 |
0.39 |
|
| 2000 |
Freedman R, Adams CE, Adler LE, Bickford PC, Gault J, Harris JG, Nagamoto HT, Olincy A, Ross RG, Stevens KE, Waldo M, Leonard S. Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia. American Journal of Medical Genetics. 97: 58-64. PMID 10813805 DOI: 10.1002/(Sici)1096-8628(200021)97:1<58::Aid-Ajmg8>3.0.Co;2-Y |
0.471 |
|
| 2000 |
Leonard S, Breese C, Adams C, Benhammou K, Gault J, Stevens K, Lee M, Adler L, Olincy A, Ross R, Freedman R. Smoking and schizophrenia : abnormal nicotinic receptor expression European Journal of Pharmacology. 393: 237-242. PMID 10771019 DOI: 10.1016/S0014-2999(00)00035-2 |
0.429 |
|
| 2000 |
Waldo MC, Adler LE, Leonard S, Olincy A, Ross RG, Harris JG, Freedman R. Familial transmission of risk factors in the first-degree relatives of schizophrenic people. Biological Psychiatry. 47: 231-9. PMID 10682220 DOI: 10.1016/S0006-3223(99)00272-3 |
0.435 |
|
| 2000 |
Olincy A, Ross RG, Freedman R. 116. The effects of aging in schizophrenia on an antisaccade eye movement task Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00378-4 |
0.359 |
|
| 1999 |
Waldo MC, Freedman R. Neurobiological abnormalities in the relatives of schizophrenics Journal of Psychiatric Research. 33: 491-495. PMID 10628524 DOI: 10.1016/S0022-3956(99)00025-4 |
0.403 |
|
| 1999 |
Freedman R. Schizophrenia as a neuronal illness. Biological Psychiatry. 46: 587-588. PMID 10472412 DOI: 10.1016/S0006-3223(99)00154-7 |
0.398 |
|
| 1999 |
Ross RG, Olincy A, Harris JG, Radant A, Adler LE, Compagnon N, Freedman R. The effects of age on a smooth pursuit tracking task in adults with schizophrenia and normal subjects. Biological Psychiatry. 46: 383-91. PMID 10435204 DOI: 10.1016/S0006-3223(98)00369-2 |
0.334 |
|
| 1999 |
Adler LE, Freedman R, Ross RG, Olincy A, Waldo MC. Elementary phenotypes in the neurobiological and genetic study of schizophrenia Biological Psychiatry. 46: 8-18. PMID 10394470 DOI: 10.1016/S0006-3223(99)00085-2 |
0.464 |
|
| 1999 |
Ross RG, Olincy A, Harris JG, Radant A, Hawkins M, Adler LE, Freedman R. Evidence for bilineal inheritance of physiological indicators of risk in childhood-onset schizophrenia. American Journal of Medical Genetics. 88: 188-99. PMID 10206241 DOI: 10.1002/(Sici)1096-8628(19990416)88:2<188::Aid-Ajmg17>3.0.Co;2-E |
0.412 |
|
| 1999 |
Freedman R, Adler LE, Leonard S. Alternative phenotypes for the complex genetics of schizophrenia. Biological Psychiatry. 45: 551-8. PMID 10088045 DOI: 10.1016/S0006-3223(98)00321-7 |
0.452 |
|
| 1999 |
Jensen J, Coon H, Hoff M, Rosenthal J, Reimherr F, Wender P, Myles-Worsley M, Freedman R, Byerley W. Search for a schizophrenia susceptibility gene on chromosome 13. Psychiatric Genetics. 8: 239-43. PMID 9861643 DOI: 10.1097/00041444-199808040-00007 |
0.372 |
|
| 1999 |
Leonard S, Stevens K, Bickford P, Adler L, Freedman R. Modeling sensory processing deficits of schizophrenia in laboratory animals European Neuropsychopharmacology. 9: 154. DOI: 10.1016/S0924-977X(99)80033-9 |
0.413 |
|
| 1998 |
Freedman R. Biological Phenotypes In The Genetics Of Schizophrenia Biological Psychiatry. 44: 939-940. PMID 9821557 DOI: 10.1016/S0006-3223(98)00271-6 |
0.4 |
|
| 1998 |
Ross RG, Olincy A, Harris JG, Radant A, Adler LE, Freedman R. Anticipatory saccades during smooth pursuit eye movements and familial transmission of schizophrenia. Biological Psychiatry. 44: 690-7. PMID 9798072 DOI: 10.1016/S0006-3223(98)00052-3 |
0.36 |
|
| 1998 |
Vallada H, Curtis D, Sham P, Kunugi H, Zhao J, Murray R, McGuffin P, Nanko S, Owen M, Gill M, Collier D, Antonarakis S, Housman D, Kazazian H, Nestadt G, ... ... Freedman R, et al. A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12 Schizophrenia Research. 32: 115-121. PMID 9713907 DOI: 10.1016/S0920-9964(98)00048-6 |
0.409 |
|
| 1998 |
Leonard S, Gault J, Moore T, Hopkins J, Robinson M, Olincy A, Adler LE, Cloninger CR, Kaufmann CA, Tsuang MT, Faraone SV, Malaspina D, Svrakic DM, Freedman R. Further investigation of a chromosome 15 locus in schizophrenia: analysis of affected sibpairs from the NIMH Genetics Initiative. American Journal of Medical Genetics. 81: 308-12. PMID 9674976 DOI: 10.1002/(Sici)1096-8628(19980710)81:4<308::Aid-Ajmg6>3.0.Co;2-P |
0.426 |
|
| 1998 |
Griffith JM, O'Neill JE, Petty F, Garver D, Young D, Freedman R. Nicotinic receptor desensitization and sensory gating deficits in schizophrenia. Biological Psychiatry. 44: 98-106. PMID 9646891 DOI: 10.1016/S0006-3223(97)00362-4 |
0.445 |
|
| 1998 |
Adler LE, Olincy A, Waldo M, Harris JG, Griffith J, Stevens K, Flach K, Nagamoto H, Bickford P, Leonard S, Freedman R. Schizophrenia, sensory gating, and nicotinic receptors. Schizophrenia Bulletin. 24: 189-202. PMID 9613620 DOI: 10.1093/Oxfordjournals.Schbul.A033320 |
0.485 |
|
| 1998 |
Stevens KE, Kem WR, Mahnir VM, Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology. 136: 320-7. PMID 9600576 DOI: 10.1007/S002130050573 |
0.389 |
|
| 1998 |
Ross RG, Harris JG, Olincy A, Radant A, Adler LE, Freedman R. Familial transmission of two independent saccadic abnormalities in schizophrenia. Schizophrenia Research. 30: 59-70. PMID 9542789 DOI: 10.1016/S0920-9964(97)00133-3 |
0.39 |
|
| 1998 |
Olincy A, Ross RG, Young DA, Roath M, Freedman R. Improvement in smooth pursuit eye movements after cigarette smoking in schizophrenic patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 18: 175-85. PMID 9471115 DOI: 10.1016/S0893-133X(97)00095-X |
0.308 |
|
| 1998 |
Leonard S, Breese CR, Gault J, Adler L, Olincy A, Lee M, Freedman R. Schizophrenia and nicotinic receptors: Gene expression and genetic linkage studies European Neuropsychopharmacology. 8. DOI: 10.1016/S0924-977X(98)80119-3 |
0.42 |
|
| 1998 |
Olincy A, Leonard S, Young DA, Sullivan B, Freedman R. 360. Elevation of bombesin by smoking is decreased in schizophrenia Biological Psychiatry. 43. DOI: 10.1016/S0006-3223(98)90808-3 |
0.381 |
|
| 1997 |
Olincy A, Young DA, Freedman R. Increased levels of the nicotine metabolite cotinine in schizophrenic smokers compared to other smokers. Biological Psychiatry. 42: 1-5. PMID 9193735 DOI: 10.1016/S0006-3223(96)00302-2 |
0.363 |
|
| 1997 |
Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, et al. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proceedings of the National Academy of Sciences of the United States of America. 94: 587-92. PMID 9012828 DOI: 10.1073/Pnas.94.2.587 |
0.468 |
|
| 1997 |
Adams CE, DeMasters BK, Freedman R. Regional zinc staining in postmortem hippocampus from schizophrenic patients. Schizophrenia Research. 18: 71-7. PMID 8929763 DOI: 10.1016/0920-9964(95)00041-0 |
0.369 |
|
| 1997 |
Nagamoto HT, Adler LE, Huettl P, Gerhardt G, Hea R, Cawthra E, Griffith J, Freedman R. Improved P50 auditory gating in schizophrenia with clozapine Schizophrenia Research. 24: 235. DOI: 10.1016/S0920-9964(97)82678-3 |
0.423 |
|
| 1997 |
Adler LE, McRae KA, Cawthra E, Ascarrunz F, Gerhardt G, Huettl P, Levin D, Abrams R, Freedman R. P50 Auditory gating, FFTs, and plasma metabolites in schizophrenia Schizophrenia Research. 24: 231. DOI: 10.1016/S0920-9964(97)82664-3 |
0.387 |
|
| 1997 |
Stevens KE, Collins AC, Marks MJ, Stitzel JA, Freedman R. Inheritance of a schizophrenia-like deficit in auditory gating fits a one gene model in inbred mouse strains Schizophrenia Research. 24: 60. DOI: 10.1016/S0920-9964(97)82167-6 |
0.387 |
|
| 1997 |
Leonard S, Byerley W, Myles-Worsley M, Olincy A, Waldo M, Adler L, Coon H, Freedman R. Linkage of a chromosome 15 locus to a neurophysiological deficit in schizophrenia Schizophrenia Research. 24: 52. DOI: 10.1016/S0920-9964(97)82148-2 |
0.4 |
|
| 1996 |
Freedman R, Adler LE, Myles-Worsley M, Nagamoto HT, Miller C, Kisley M, McRae K, Cawthra E, Waldo M. Inhibitory gating of an evoked response to repeated auditory stimuli in schizophrenic and normal subjects. Human recordings, computer simulation, and an animal model. Archives of General Psychiatry. 53: 1114-21. PMID 8956677 DOI: 10.1001/Archpsyc.1996.01830120052009 |
0.356 |
|
| 1996 |
McCarley RW, Hsiao JK, Freedman R, Pfefferbaum A, Donchin E. Neuroimaging and the cognitive neuroscience of schizophrenia. Schizophrenia Bulletin. 22: 703-25. PMID 8938923 DOI: 10.1093/Schbul/22.4.703 |
0.412 |
|
| 1996 |
Yaw J, Myles-Worsley M, Hoff M, Holik J, Freedman R, Byerley W, Coon H. Anticipation in multiplex schizophrenia pedigrees. Psychiatric Genetics. 6: 7-11. PMID 8925257 DOI: 10.1097/00041444-199621000-00002 |
0.401 |
|
| 1996 |
Leonard S, Adams C, Breese CR, Adler LE, Bickford P, Byerley W, Coon H, Griffith JM, Miller C, Myles-Worsley M, Nagamoto HT, Rollins Y, Stevens KE, Waldo M, Freedman R. Nicotinic receptor function in schizophrenia. Schizophrenia Bulletin. 22: 431-45. PMID 8873294 DOI: 10.1093/Schbul/22.3.431 |
0.481 |
|
| 1996 |
Stevens KE, Freedman R, Collins AC, Hall M, Leonard S, Marks MJ, Rose GM. Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 152-62. PMID 8840351 DOI: 10.1016/0893-133X(95)00178-G |
0.34 |
|
| 1996 |
Nagamoto HT, Adler LE, Hea RA, Griffith JM, McRae KA, Freedman R. Gating of auditory P50 in schizophrenics: unique effects of clozapine. Biological Psychiatry. 40: 181-8. PMID 8830951 DOI: 10.1016/0006-3223(95)00371-1 |
0.381 |
|
| 1996 |
Harris JG, Adler LE, Young DA, Cullum CM, Rilling LM, Cicerello A, Intemann PM, Freedman R. Neuropsychological dysfunction in parents of schizophrenics. Schizophrenia Research. 20: 253-60. PMID 8827851 DOI: 10.1016/0920-9964(96)00009-6 |
0.343 |
|
| 1996 |
Young DA, Waldo M, Rutledge JH, Freedman R. Heritability of inhibitory gating of the p50 auditory-evoked potential in monozygotic and dizygotic twins Neuropsychobiology. 33: 113-117. PMID 8776738 DOI: 10.1159/000119260 |
0.367 |
|
| 1996 |
Ross RG, Hommer D, Radant A, Roath M, Freedman R. Early expression of smooth-pursuit eye movement abnormalities in children of schizophrenic parents. Journal of the American Academy of Child and Adolescent Psychiatry. 35: 941-9. PMID 8768356 DOI: 10.1097/00004583-199607000-00022 |
0.308 |
|
| 1996 |
Freedman R, Adler L, Cawthra E, Harris J, McRae K, Olincy A, Ross R, Sullivan B, Waldo M, Young D. Attention and sensory gating deficits in relatives of schizophrenic patients Biological Psychiatry. 39: 501. DOI: 10.1016/0006-3223(96)83956-4 |
0.327 |
|
| 1995 |
Waldo M, Myles-Worsley M, Madison A, Byerley W, Freedman R. Sensory gating deficits in parents of schizophrenics American Journal of Medical Genetics - Neuropsychiatric Genetics. 60: 506-511. PMID 8825886 DOI: 10.1002/Ajmg.1320600605 |
0.44 |
|
| 1995 |
Breese CR, Freedman R, Leonard SS. Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers Brain Research. 674: 82-90. PMID 7773698 DOI: 10.1016/0006-8993(94)01384-T |
0.308 |
|
| 1995 |
Hershman KM, Freedman R, Bickford PC. GABAB antagonists diminish the inhibitory gating of auditory response in the rat hippocampus. Neuroscience Letters. 190: 133-6. PMID 7644122 DOI: 10.1016/0304-3940(95)11523-Y |
0.307 |
|
| 1995 |
Fang N, Coon H, Hoff M, Holik J, Hadley D, Reimherr F, Wender P, Myles-Worsley M, Waldo M, Freedman R, Byerley W. Search for a schizophrenia susceptibility gene on chromosome 18 Psychiatric Genetics. 5: 31-35. PMID 7582878 DOI: 10.1097/00041444-199521000-00005 |
0.362 |
|
| 1995 |
Griffith J, Hoffer LD, Adler LE, Zerbe GO, Freedman R. Effects of sound intensity on a midlatency evoked response to repeated auditory stimuli in schizophrenic and normal subjects. Psychophysiology. 32: 460-6. PMID 7568640 DOI: 10.1111/J.1469-8986.1995.Tb02097.X |
0.311 |
|
| 1995 |
Freedman R, Hall M, Adler LE, Leonard S. Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biological Psychiatry. 38: 22-33. PMID 7548469 DOI: 10.1016/0006-3223(94)00252-X |
0.41 |
|
| 1995 |
Myles-Worsley M, Yaw J, Coon H, Byerley W, Freedman R. P50 sensory gating in children of multiplex schizophrenia families Schizophrenia Research. 15: 44. DOI: 10.1016/0920-9964(95)95141-U |
0.374 |
|
| 1994 |
Freedman R, Adler LE, Bickford P, Byerley W, Coon H, Cullum CM, Griffith JM, Harris JG, Leonard S, Miller C. Schizophrenia and nicotinic receptors. Harvard Review of Psychiatry. 2: 179-92. PMID 9384901 DOI: 10.3109/10673229409017136 |
0.477 |
|
| 1994 |
Griffith JM, Adler LE, Freedman R. Fine motor performance in schizophrenia. Neuropsychobiology. 29: 179-84. PMID 8047244 DOI: 10.1159/000119084 |
0.312 |
|
| 1994 |
Waldo MC, Cawthra E, Adler LE, Dubester S, Staunton M, Nagamoto H, Baker N, Madison A, Simon J, Scherzinger A, Drebing C, Gerhardt G, Freedman R. Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings Schizophrenia Research. 12: 93-106. PMID 8043530 DOI: 10.1016/0920-9964(94)90067-1 |
0.408 |
|
| 1994 |
Issa F, Kirch DG, Gerhardt GA, Bartko JJ, Suddath RL, Freedman R, Wyatt RJ. A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: II. Correlations with psychopathology. Psychiatry Research. 52: 251-8. PMID 7991719 DOI: 10.1016/0165-1781(94)90070-1 |
0.373 |
|
| 1994 |
Issa F, Gerhardt GA, Bartko JJ, Suddath RL, Lynch M, Gamache PH, Freedman R, Wyatt RJ, Kirch DG. A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: I. Comparisons with healthy control subjects and neuroleptic-treated/unmedicated pairs analyses. Psychiatry Research. 52: 237-49. PMID 7991718 DOI: 10.1016/0165-1781(94)90069-8 |
0.408 |
|
| 1994 |
Coon H, Jensen S, Holik J, Hoff M, Myles-Worsley M, Reimherr F, Wender P, Waldo M, Freedman R, Leppert M, Byerley W. Genomic scan for genes predisposing to schizophrenia American Journal of Medical Genetics. 54: 59-71. PMID 7909992 DOI: 10.1002/Ajmg.1320540111 |
0.311 |
|
| 1994 |
Freedman R, Strömberg I, Nordström AL, Seiger A, Olson L, Bygdeman M, Wiesel FA, Granholm AC, Hoffer BJ. Neuronal development in embryonic brain tissue derived from schizophrenic women and grafted to animal hosts. Schizophrenia Research. 13: 259-70. PMID 7841140 DOI: 10.1016/0920-9964(94)90051-5 |
0.343 |
|
| 1994 |
Hall M, Freedman R, Adler LE, Leonard S. Decreased numbers of hipocampal nicotinic receptors in schizophrenia Biological Psychiatry. 35: 700. DOI: 10.1016/0006-3223(94)90965-2 |
0.438 |
|
| 1994 |
Griffith J, Hoffer LJ, Adler LE, Freedman R. Effects of sound intensity on auditory P50 gating in schizophrenics and normals Biological Psychiatry. 35: 630. DOI: 10.1016/0006-3223(94)90712-9 |
0.313 |
|
| 1993 |
Coon H, Plaetke R, Holik J, Hoff M, Myles-Worsley M, Waldo M, Freedman R, Byerley W. Use of a neurophysiological trait in linkage analysis of schizophrenia Biological Psychiatry. 34: 277-289. PMID 8399828 DOI: 10.1016/0006-3223(93)90085-R |
0.416 |
|
| 1993 |
Cullum CM, Harris JG, Waldo MC, Smernoff E, Madison A, Nagamoto HT, Griffith J, Adler LE, Freedman R. Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia. Schizophrenia Research. 10: 131-41. PMID 8398945 DOI: 10.1016/0920-9964(93)90048-N |
0.39 |
|
| 1993 |
Browning MD, Dudek EM, Rapier JL, Leonard S, Freedman R. Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biological Psychiatry. 34: 529-35. PMID 8274580 DOI: 10.1016/0006-3223(93)90195-J |
0.36 |
|
| 1993 |
Adler LE, Hoffer LD, Wiser A, Freedman R. Normalization of auditory physiology by cigarette smoking in schizophrenic patients. The American Journal of Psychiatry. 150: 1856-61. PMID 8238642 DOI: 10.1176/Ajp.150.12.1856 |
0.368 |
|
| 1993 |
Griffith JM, Waldo M, Adler LE, Freedman R. Normalization of auditory sensory gating in schizophrenic patients after a brief period for sleep Psychiatry Research. 49: 29-39. PMID 8140180 DOI: 10.1016/0165-1781(93)90028-F |
0.326 |
|
| 1993 |
Leonard S, Rollins Y, Logel J, Drebing C, Dill D, Hall M, Freedman R. Neurochemistry/molecular biologyExpression of the α7 nicotinic acetylcholine receptor subunit in normal and schizophrenic postmortem brain Schizophrenia Research. 9: 223. DOI: 10.1016/0920-9964(93)90485-2 |
0.315 |
|
| 1993 |
Issa F, Gerhardt G, Bartko J, Suddath R, Lynch M, Gamache P, Freedman R, Wyatt R, Kirch D. Cerebrospinal fluid biogenic amines in schizophrenia: Multi-dimensional neurochemical and multivariate statistical approaches Schizophrenia Research. 9: 221. DOI: 10.1016/0920-9964(93)90480-7 |
0.369 |
|
| 1993 |
Cullum C, Harris J, Werner J, Waldo M, Smernoff E, Madison A, Nagamoto H, Adler L, Freedman R. Verbal learning dysfunction in schizophrenia Schizophrenia Research. 9: 173. DOI: 10.1016/0920-9964(93)90332-D |
0.375 |
|
| 1993 |
Freedman R, Adler LE, Griffith J, Waldo M, Olson L, Miller C, Bickford P, Stevens K, Hall M, Leonard S. Desensitization of nicotinic receptors on inhibitory interneurons as a possible pathophysiological mechanism in schizophrenia Schizophrenia Research. 9: 156. DOI: 10.1016/0920-9964(93)90283-O |
0.449 |
|
| 1993 |
Adler LE, Hoffer LJ, Griffith J, Waldo M, Wieser A, Freedman R. Normalization of deficient P50 auditory sensory gating in schizophrenic patients and their first degree relatives by nicotine Schizophrenia Research. 9: 153. DOI: 10.1016/0920-9964(93)90272-K |
0.352 |
|
| 1992 |
Luntz-Leybman V, Bickford PC, Freedman R. Cholinergic gating of response to auditory stimuli in rat hippocampus. Brain Research. 587: 130-6. PMID 1525643 DOI: 10.1016/0006-8993(92)91437-J |
0.331 |
|
| 1992 |
Waldo M, Gerhardt G, Baker N, Drebing C, Adler L, Freedman R. Auditory sensory gating and catecholamine metabolism in schizophrenic and normal subjects. Psychiatry Research. 44: 21-32. PMID 1461944 DOI: 10.1016/0165-1781(92)90066-C |
0.358 |
|
| 1992 |
Adler LE, Hoffer LJ, Griffith J, Waldo MC, Freedman R. Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics. Biological Psychiatry. 32: 607-16. PMID 1450287 DOI: 10.1016/0006-3223(92)90073-9 |
0.443 |
|
| 1992 |
Miller CL, Bickford PC, Luntz-Leybman V, Adler LE, Gerhardt GA, Freedman R. Phencyclidine and auditory sensory gating in the hippocampus of the rat. Neuropharmacology. 31: 1041-8. PMID 1436386 DOI: 10.1016/0028-3908(92)90106-Y |
0.303 |
|
| 1992 |
Freedman R, Strömberg I, Seiger A, Olson L, Nordström AL, Wiesel FA, Bygdeman M, Wetmore C, Palmer MR, Hoffer BJ. Initial studies of embryonic transplants of human hippocampus and cerebral cortex derived from schizophrenic women. Biological Psychiatry. 32: 1148-63. PMID 1362085 DOI: 10.1016/0006-3223(92)90194-5 |
0.309 |
|
| 1992 |
Myles-Worsley M, Dale P, Polloi A, Levy D, Freedman R, Byerley W. Eye Tracking Abnormalities in Two Micronesian Families with Schizophrenia Psychiatric Genetics. 2: 209-212. DOI: 10.1097/00041444-199203000-00005 |
0.379 |
|
| 1991 |
Nagamoto HT, Adler LE, Waldo MC, Griffith J, Freedman R. Gating of auditory response in schizophrenics and normal controls. Effects of recording site and stimulation interval on the P50 wave Schizophrenia Research. 4: 31-40. PMID 1848997 DOI: 10.1016/0920-9964(91)90007-E |
0.313 |
|
| 1991 |
Waldo MC, Carey G, Myles-Worsley M, Cawthra E, Adler LE, Nagamoto HT, Wender P, Byerley W, Plaetke R, Freedman R. Codistribution of a sensory gating deficit and schizophrenia in multi-affected families Psychiatry Research. 39: 257-268. PMID 1798824 DOI: 10.1016/0165-1781(91)90092-4 |
0.446 |
|
| 1991 |
Baker NJ, Kirch DG, Waldo M, Bell J, Adler LE, Hattox S, Murphy R, Freedman R. Plasma homovanillic acid and prognosis in Schizophrenia Biological Psychiatry. 29: 192-196. PMID 1671646 DOI: 10.1016/0006-3223(91)90048-Q |
0.357 |
|
| 1991 |
Freedman R, Waldo M, Bickford-Wimer P, Nagamoto H. Elementary neuronal dysfunctions in schizophrenia Schizophrenia Research. 4: 233-243. PMID 1645590 DOI: 10.1016/0920-9964(91)90035-P |
0.456 |
|
| 1991 |
Freedman R. A VA national research symposium on schizophrenia Schizophrenia Research. 4: 67-69. DOI: 10.1016/0920-9964(91)90025-M |
0.391 |
|
| 1990 |
Adler LE, Gerhardt GA, Franks R, Baker N, Nagamoto H, Drebing C, Freedman R. Sensory physiology and catecholamines in schizophrenia and mania. Psychiatry Research. 31: 297-309. PMID 2333360 DOI: 10.1016/0165-1781(90)90099-Q |
0.42 |
|
| 1990 |
Baker NJ, Staunton M, Adler LE, Gerhardt GA, Drebing C, Waldo M, Nagamoto H, Freedman R. Sensory gating deficits in psychiatric inpatients: relation to catecholamine metabolites in different diagnostic groups. Biological Psychiatry. 27: 519-28. PMID 2310807 DOI: 10.1016/0006-3223(90)90443-6 |
0.373 |
|
| 1990 |
Bickford-Wimer PC, Nagamoto H, Johnson R, Adler LE, Egan M, Rose GM, Freedman R. Auditory sensory gating in hippocampal neurons: a model system in the rat. Biological Psychiatry. 27: 183-92. PMID 2294981 DOI: 10.1016/0006-3223(90)90648-L |
0.322 |
|
| 1990 |
Adler LE, Waldo MC, Tatcher A, Cawthra E, Baker N, Freedman R. Lack of relationship of auditory gating defects to negative symptoms in schizophrenia Schizophrenia Research. 3: 131-138. PMID 2278977 DOI: 10.1016/0920-9964(90)90046-A |
0.435 |
|
| 1989 |
Nagamoto HT, Adler LE, Waldo MC, Freedman R. Sensory gating in schizophrenics and normal controls: Effects of changing stimulation interval Biological Psychiatry. 25: 549-561. PMID 2920190 DOI: 10.1016/0006-3223(89)90215-1 |
0.364 |
|
| 1989 |
de la Garza R, Freedman R, Hoffer BJ. Kappa-bungarotoxin blockade of nicotine electrophysiological actions in cerebellar Purkinje neurons. Neuroscience Letters. 99: 95-100. PMID 2748023 DOI: 10.1016/0304-3940(89)90271-1 |
0.317 |
|
| 1989 |
de la Garza R, Freedman R, Hoffer J. Nicotine-induced inhibition of cerebellar Purkinje neurons: specific actions of nicotine and selective blockade by mecamylamine. Neuropharmacology. 28: 495-501. PMID 2725857 DOI: 10.1016/0028-3908(89)90085-3 |
0.32 |
|
| 1989 |
Nagamoto HT, Adler LE, Waldo MC, Freedman R. Sensory gating in schizophrenics and normal controls: Evidence for heterogeneity in schizophrenics Schizophrenia Research. 2: 86. DOI: 10.1016/0920-9964(89)90122-9 |
0.336 |
|
| 1989 |
Freedman R, Adler L, Bickford-Wimer P, Drebing C, Gerhardt G, Granholm A, Hoffer B, Nagamoto H, Olson L, Rose G, Waldo M. Candidate neuronal mechanisms for abnormal sensory gating in schizophrenia Schizophrenia Research. 2: 82. DOI: 10.1016/0920-9964(89)90118-7 |
0.415 |
|
| 1989 |
Staunton M, Waldo M, Cawthra E, Adler LE, Baker N, Nagomoto H, Freedman R. Auditory sensory gating in schizophrenics and their siblings Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91549-7 |
0.302 |
|
| 1989 |
Nagamoto HT, Adler LE, Waldo MC, Freedman R. Sensory gating in schizophrenics and normal controls: Evidence for heterogeneity in schizophrenics Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91534-5 |
0.336 |
|
| 1988 |
Waldo MC, Adler LE, Freedman R. Defects in auditory sensory gating and their apparent compensation in relatives of schizophrenics Schizophrenia Research. 1: 19-24. PMID 3154501 DOI: 10.1016/0920-9964(88)90035-7 |
0.303 |
|
| 1988 |
Parfitt KD, Freedman R, Bickford-Wimer PC. Electrophysiological effects of locally applied noradrenergic agents at cerebellar Purkinje neurons: receptor specificity. Brain Research. 462: 242-51. PMID 2847850 DOI: 10.1016/0006-8993(88)90552-5 |
0.3 |
|
| 1987 |
de la Garza R, McGuire TJ, Freedman R, Hoffer BJ. The electrophysiological effects of nicotine in the rat cerebellum: evidence for direct postsynaptic actions. Neuroscience Letters. 80: 303-8. PMID 3683986 DOI: 10.1016/0304-3940(87)90472-1 |
0.316 |
|
| 1987 |
Waldo MC, Graze K, Bender SdG, Adler LE, Freedman R. Premenstrual mood changes and gating of the auditory evoked potential Psychoneuroendocrinology. 12: 35-40. PMID 3588811 DOI: 10.1016/0306-4530(87)90020-5 |
0.304 |
|
| 1987 |
Baker N, Adler LE, Franks RD, Waldo M, Berry S, Nagamoto H, Muckle A, Freedman R. Neurophysiological assessment of sensory gating in psychiatric inpatients: Comparison between schizophrenia and other diagnoses Biological Psychiatry. 22: 603-617. PMID 3580435 DOI: 10.1016/0006-3223(87)90188-0 |
0.431 |
|
| 1987 |
Freedman R, Adler LE, Baker N, Waldo M, Mizner G. Candidate for inherited neurobiological dysfunction in schizophrenia Somatic Cell and Molecular Genetics. 13: 479-484. PMID 3455019 DOI: 10.1007/Bf01534952 |
0.427 |
|
| 1987 |
de la Garza R, McGuire TJ, Freedman R, Hoffer BJ. Selective antagonism of nicotine actions in the rat cerebellum with alpha-bungarotoxin. Neuroscience. 23: 887-91. PMID 3437995 DOI: 10.1016/0306-4522(87)90165-5 |
0.334 |
|
| 1987 |
Freedman R, Adler LE, Gerhardt GA, Waldo M, Baker N, Rose GM, Drebing C, Nagamoto H, Bickford-Wimer P, Franks R. Neurobiological studies of sensory gating in schizophrenia. Schizophrenia Bulletin. 13: 669-78. PMID 2894074 DOI: 10.1093/Schbul/13.4.669 |
0.457 |
|
| 1986 |
Waldo MC, Freedman R. Gating of auditory evoked responses in normal college students Psychiatry Research. 19: 233-239. PMID 3797550 DOI: 10.1016/0165-1781(86)90102-2 |
0.308 |
|
| 1986 |
Adler LE, Rose G, Freedman R. Neurophysiological studies of sensory gating in rats: effects of amphetamine, phencyclidine, and haloperidol. Biological Psychiatry. 21: 787-98. PMID 3730461 DOI: 10.1016/0006-3223(86)90244-1 |
0.32 |
|
| 1986 |
Waldo M, Adler L, Franks R, Baker N, Siegel C, Freedman R. Sensory gating and schizophrenia Biological Psychology. 23: 108. DOI: 10.1016/0301-0511(86)90143-2 |
0.429 |
|
| 1985 |
Adler LE, Waldo MC, Freedman R. Neurophysiologic studies of sensory gating in schizophrenia: Comparison of auditory and visual responses Biological Psychiatry. 20: 1284-1296. PMID 4063418 DOI: 10.1016/0006-3223(85)90113-1 |
0.34 |
|
| 1985 |
Kirch DG, Palmer MR, Egan M, Freedman R. Electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain Neuropharmacology. 24: 375-379. PMID 2862598 DOI: 10.1016/0028-3908(85)90021-8 |
0.302 |
|
| 1984 |
Siegel C, Waldo M, Mizner G, Adler LE, Freedman R. Deficits in Sensory Gating in Schizophrenic Patients and Their Relatives: Evidence Obtained With Auditory Evoked Responses Archives of General Psychiatry. 41: 607-612. PMID 6732421 DOI: 10.1001/Archpsyc.1984.01790170081009 |
0.4 |
|
| 1983 |
Freedman R, Kirch D, Bell J, Adler LE, Pecevich M, Pachtman E, Denver P. Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs. Acta Psychiatrica Scandinavica. 65: 35-45. PMID 6138923 DOI: 10.1111/J.1600-0447.1982.Tb00819.X |
0.392 |
|
| 1982 |
Palmer MR, Freedman R, Dunwiddie TV. Interactions of a neuroleptic drug (fluphenazine) with catecholamines in hippocampus. Psychopharmacology. 76: 122-9. PMID 6805021 DOI: 10.1007/Bf00435265 |
0.31 |
|
| 1981 |
Marwaha J, Hoffer BJ, Geller HM, Freedman R. Electrophysiologic interactions of antipsychotic drugs with central noradrenergic pathways. Psychopharmacology. 73: 126-33. PMID 6112771 DOI: 10.1007/Bf00429202 |
0.326 |
|
| 1979 |
Freedman R, Schwab PJ. Paranoid symptoms in patients on a general hospital psychiatric unit. Implications for diagnosis and treatment. Archives of General Psychiatry. 35: 387-90. PMID 727891 DOI: 10.1001/Archpsyc.1978.01770270137014 |
0.358 |
|
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