Philip J. Scarpace - Publications

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Pharmacology, Genetics, Neuroscience Biology, Public Health

140/211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Golden MP, Côté I, Green SM, Toklu HZ, Tüme N, Scarpace PJ, Yarrow JF. The Effects of Leptin and Estradiol Administration on Cancellous Bone Microarchitecture in Male Rats Medicine & Science in Sports & Exercise. 51: 755. DOI: 10.1249/01.Mss.0000562750.58750.53  0.364
2018 Côté I, Green SM, Yarrow JF, Conover CF, Toklu HZ, Morgan D, Carter CS, Tümer N, Scarpace PJ. Estradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in rats. Journal of Neuroendocrinology. e12646. PMID 30246441 DOI: 10.1111/Jne.12646  0.502
2018 Cote I, Toklu HZ, Green SM, Morgan D, Carter CS, Tumer N, Scarpace PJ. Limiting feeding to the active phase reduces blood pressure without the necessity of caloric reduction or fat mass loss. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 30024775 DOI: 10.1152/Ajpregu.00076.2018  0.452
2018 Bruce EB, Sakarya Y, Kirichenko N, Toklu HZ, Sumners C, Morgan D, Tümer N, Scarpace PJ, Carter CS. ACE2 activator diminazene aceturate reduces adiposity but preserves lean mass in young and old rats. Experimental Gerontology. PMID 30006298 DOI: 10.1016/J.Exger.2018.07.008  0.553
2018 Scarpace P, Côté I, Green S, Morgan D, Carter C, Tümer N. ESTRADIOL AND LEPTIN OVEREXPRESSION HAVE INDEPENDENT MODES OF ACTION ON DECREASED FOOD INTAKE AND BODY WEIGHT IN MALES RATS Journal of Hypertension. 36: e84. DOI: 10.1097/01.Hjh.0000539206.85977.8D  0.457
2017 Côté I, Green SM, Morgan D, Carter C, Tümer N, Scarpace PJ. Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reduction. Canadian Journal of Physiology and Pharmacology. PMID 29131966 DOI: 10.1139/Cjpp-2017-0440  0.415
2017 Cote I, Sakarya Y, Green SM, Morgan D, Carter CS, Tumer N, Scarpace PJ. iBAT sympathetic innervation is not required for body weight loss induced by central leptin delivery. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00219.2017. PMID 29089334 DOI: 10.1152/Ajpendo.00219.2017  0.486
2017 Côté I, Green SM, Toklu HZ, Morgan D, Carter CS, Tümer N, Scarpace PJ. Differential physiological responses to central leptin overexpression in male and female rats. Journal of Neuroendocrinology. PMID 29044801 DOI: 10.1111/Jne.12552  0.404
2017 Basgut B, Whidden MA, Kirichenko N, Woods M, Erdos B, Scarpace PJ, Tümer N. Effect of High-Salt Diet on Age-Related High Blood Pressure and Hypothalamic Redox Signaling. Pharmacology. 100: 105-114. PMID 28521325 DOI: 10.1159/000472259  0.351
2017 Scarpace P, Cote I, Toklu H, Tumer N. [Lb.02.29] Feeding Schedule Reduces Blood Pressure But Does Not Protect Against Diet-Induced Obesity In Rats Journal of Hypertension. 35. DOI: 10.1097/01.Hjh.0000523754.95393.4A  0.47
2016 Côté I, Sakarya Y, Kirichenko N, Morgan D, Carter CS, Tümer N, Scarpace PJ. Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction. Canadian Journal of Physiology and Pharmacology. 1-9. PMID 28051332 DOI: 10.1139/Cjpp-2016-0290  0.408
2016 Toklu HZ, Scarpace PJ, Sakarya Y, Kirichenko N, Matheny M, Bruce EB, Carter CS, Morgan D, Tümer N. Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change STAT3 signalling or SIRT1/AMPK pathway. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. 1-9. PMID 28006433 DOI: 10.1139/Apnm-2016-0067  0.467
2016 Gocmez SS, Scarpace PJ, Whidden MA, Erdos B, Kirichenko N, Sakarya Y, Utkan T, Tumer N. Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries. Journal of Exercise Nutrition & Biochemistry. 20: 41-8. PMID 27298812 DOI: 10.20463/Jenb.2016.03.20.1.2  0.343
2016 Toklu HZ, Bruce EB, Sakarya Y, Carter CS, Morgan D, Matheny MK, Kirichenko N, Scarpace PJ, Tümer N. Anorexic response to rapamycin does not appear to involve a central mechanism. Clinical and Experimental Pharmacology & Physiology. PMID 27232670 DOI: 10.1111/1440-1681.12601  0.503
2016 Toklu HZ, Muller-Delp J, Sakaraya Y, Oktay S, Kirichenko N, Matheny M, Carter CS, Morgan D, Strehler KY, Tumer N, Scarpace PJ. High dietary fructose does not exacerbate the detrimental consequences of high fat diet on basilar artery function. Journal of Physiology and Pharmacology : An Official Journal of the Polish Physiological Society. 67: 205-16. PMID 27226180  0.343
2016 Gocmez SS, Gacar N, Utkan T, Gacar G, Scarpace PJ, Tumer N. Protective effects of resveratrol on aging-induced cognitive impairment in rats. Neurobiology of Learning and Memory. 131: 131-6. PMID 27040098 DOI: 10.1016/J.Nlm.2016.03.022  0.377
2016 Strehler KY, Matheny M, Kirichenko N, Sakarya Y, Bruce E, Toklu HZ, Carter CS, Morgan D, Tümer N, Scarpace PJ. Onset of leptin resistance shows temporal differences related to dose or pulsed treatment. European Journal of Pharmacology. PMID 27012992 DOI: 10.1016/J.Ejphar.2016.03.026  0.415
2016 Yarrow JF, Toklu HZ, Balaez A, Phillips EG, Otzel DM, Chen C, Wronski TJ, Aguirre JI, Sakarya Y, Tümer N, Scarpace PJ. Fructose consumption does not worsen bone deficits resulting from high-fat feeding in young male rats. Bone. PMID 26855373 DOI: 10.1016/J.Bone.2016.02.004  0.374
2015 Carter CS, Khamiss D, Matheny M, Toklu HZ, Kirichenko N, Strehler KY, Tümer N, Scarpace PJ, Morgan D. Rapamycin Versus Intermittent Feeding: Dissociable Effects on Physiological and Behavioral Outcomes When Initiated Early and Late in Life. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25617380 DOI: 10.1093/Gerona/Glu238  0.439
2015 Scarpace PJ, Matheny M, Strehler KY, Toklu HZ, Kirichenko N, Carter CS, Morgan D, Tümer N. Rapamycin Normalizes Serum Leptin by Alleviating Obesity and Reducing Leptin Synthesis in Aged Rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25617379 DOI: 10.1093/Gerona/Glu230  0.56
2015 Tumer N, Toklu HZ, Muller-Delp J, Sakarya Y, Oktay S, Matheny M, Kirichenko N, Carter C, Morgan D, Scarpace PJ. Pp.19.20: High Fat Plus Dietary Fructose Is Not More Deleterious Than A High Fat Diet On Cardiovascular Health Journal of Hypertension. 33. DOI: 10.1097/01.Hjh.0000468299.75276.Bb  0.38
2014 Matheny M, Strehler KYE, King M, Tümer N, Scarpace PJ. Targeted leptin receptor blockade: Role of ventral tegmental area and nucleus of the solitary tract leptin receptors in body weight homeostasis Journal of Endocrinology. 222: 27-41. PMID 24920667 DOI: 10.1530/Joe-13-0455  0.485
2014 Tümer N, Toklu HZ, Muller-Delp JM, Oktay S, Ghosh P, Strang K, Delp MD, Scarpace PJ. The effects of aging on the functional and structural properties of the rat basilar artery. Physiological Reports. 2. PMID 24907295 DOI: 10.14814/Phy2.12031  0.347
2014 Toklu HZ, Kwon OS, Sakarya Y, Powers SK, Llinas K, Kirichenko N, Sollanek KJ, Wiggs MP, Smuder AJ, Talbert EE, Scarpace PJ, Tümer N. The effects of enalapril and losartan on mechanical ventilation-induced sympathoadrenal activation and oxidative stress in rats. The Journal of Surgical Research. 188: 510-6. PMID 24630519 DOI: 10.1016/J.Jss.2014.01.054  0.313
2013 Tümer N, Svetlov S, Whidden M, Kirichenko N, Prima V, Erdos B, Sherman A, Kobeissy F, Yezierski R, Scarpace PJ, Vierck C, Wang KK. Overpressure blast-wave induced brain injury elevates oxidative stress in the hypothalamus and catecholamine biosynthesis in the rat adrenal medulla. Neuroscience Letters. 544: 62-7. PMID 23570732 DOI: 10.1016/J.Neulet.2013.03.042  0.365
2013 Vasselli JR, Scarpace PJ, Harris RB, Banks WA. Dietary components in the development of leptin resistance. Advances in Nutrition (Bethesda, Md.). 4: 164-75. PMID 23493533 DOI: 10.3945/An.112.003152  0.507
2013 Scarpace PJ, Matheny M, Kirichenko N, Gao YX, Tümer N, Zhang Y. Leptin overexpression in VTA trans-activates the hypothalamus whereas prolonged leptin action in either region cross-desensitizes Neuropharmacology. 65: 90-100. PMID 22982569 DOI: 10.1016/J.Neuropharm.2012.09.005  0.47
2012 Scarpace ET, Matheny M, Strehler KY, Shapiro A, Cheng KY, Tümer N, Scarpace PJ. Simultaneous introduction of a novel high fat diet and wheel running induces anorexia. Physiology & Behavior. 105: 909-14. PMID 22115947 DOI: 10.1016/J.Physbeh.2011.11.011  0.469
2011 Andino LM, Ryder DJ, Shapiro A, Matheny MK, Zhang Y, Judge MK, Cheng KY, Tümer N, Scarpace PJ. POMC overexpression in the ventral tegmental area ameliorates dietary obesity. The Journal of Endocrinology. 210: 199-207. PMID 21565854 DOI: 10.1530/Joe-10-0418  0.807
2011 Erdos B, Kirichenko N, Whidden M, Basgut B, Woods M, Cudykier I, Tawil R, Scarpace PJ, Tumer N. Effect of age on high-fat diet-induced hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 301: H164-72. PMID 21551274 DOI: 10.1152/Ajpheart.01289.2010  0.542
2011 Shapiro A, Tümer N, Gao Y, Cheng KY, Scarpace PJ. Prevention and reversal of diet-induced leptin resistance with a sugar-free diet despite high fat content. The British Journal of Nutrition. 106: 390-7. PMID 21418711 DOI: 10.1017/S000711451100033X  0.464
2011 Zhang Y, Rodrigues E, Li G, Gao Y, King M, Carter CS, Tumer N, Cheng KY, Scarpace PJ. Simultaneous POMC gene transfer to hypothalamus and brainstem increases physical activity, lipolysis and reduces adult-onset obesity. The European Journal of Neuroscience. 33: 1541-50. PMID 21366729 DOI: 10.1111/J.1460-9568.2011.07633.X  0.549
2011 Matheny M, Shapiro A, Tümer N, Scarpace PJ. Region-specific diet-induced and leptin-induced cellular leptin resistance includes the ventral tegmental area in rats. Neuropharmacology. 60: 480-7. PMID 21059361 DOI: 10.1016/J.Neuropharm.2010.11.002  0.479
2011 Shapiro A, Cheng KY, Gao Y, Seo DO, Anton S, Carter CS, Zhang Y, Tumer N, Scarpace PJ. The act of voluntary wheel running reverses dietary hyperphagia and increases leptin signaling in ventral tegmental area of aged obese rats. Gerontology. 57: 335-42. PMID 20881371 DOI: 10.1159/000321343  0.569
2010 Zhang Y, Rodrigues E, Gao YX, King M, Cheng KY, Erdös B, Tümer N, Carter C, Scarpace PJ. Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity Neuroscience. 169: 1662-1671. PMID 20538045 DOI: 10.1016/J.Neuroscience.2010.06.001  0.561
2010 Scarpace PJ, Matheny M, Zhang Y. Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area Physiology and Behavior. 100: 173-179. PMID 20193697 DOI: 10.1016/J.Physbeh.2010.02.017  0.496
2010 Zhang Y, Collazo R, Gao Y, Li G, Scarpace PJ. Intermittent MTII application evokes repeated anorexia and robust fat and weight loss. Peptides. 31: 639-43. PMID 20034526 DOI: 10.1016/J.Peptides.2009.12.019  0.506
2009 Matheny M, Zhang Y, Shapiro A, Tümer N, Scarpace PJ. Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1254-61. PMID 19726711 DOI: 10.1152/Ajpregu.90449.2008  0.558
2009 Erdos B, Broxson CS, Cudykier I, Basgut B, Whidden M, Landa T, Scarpace PJ, Tümer N. Effect of high-fat diet feeding on hypothalamic redox signaling and central blood pressure regulation. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 32: 983-8. PMID 19713964 DOI: 10.1038/Hr.2009.129  0.504
2009 Judge MK, Zhang Y, Scarpace PJ. Responses to the cannabinoid receptor-1 antagonist, AM251, are more robust with age and with high-fat feeding. The Journal of Endocrinology. 203: 281-90. PMID 19679649 DOI: 10.1677/Joe-09-0210  0.827
2009 Zhang J, Scarpace PJ. The soluble leptin receptor neutralizes leptin-mediated STAT3 signalling and anorexic responses in vivo. British Journal of Pharmacology. 158: 475-82. PMID 19422379 DOI: 10.1111/J.1476-5381.2009.00246.X  0.765
2009 Manfredsson FP, Tumer N, Erdos B, Landa T, Broxson CS, Sullivan LF, Rising AC, Foust KD, Zhang Y, Muzyczka N, Gorbatyuk OS, Scarpace PJ, Mandel RJ. Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 980-91. PMID 19277011 DOI: 10.1038/Mt.2009.45  0.496
2009 Scarpace PJ, Zhang Y. Leptin resistance: a prediposing factor for diet-induced obesity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R493-500. PMID 19091915 DOI: 10.1152/Ajpregu.90669.2008  0.484
2008 Shapiro A, Mu W, Roncal C, Cheng KY, Johnson RJ, Scarpace PJ. Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1370-5. PMID 18703413 DOI: 10.1152/Ajpregu.00195.2008  0.576
2008 Judge MK, Zhang J, Tümer N, Carter C, Daniels MJ, Scarpace PJ. Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 295: R773-R780. PMID 18596107 DOI: 10.1152/Ajpregu.00727.2007  0.785
2008 Shapiro A, Matheny M, Zhang Y, Tümer N, Cheng KY, Rogrigues E, Zolotukhin S, Scarpace PJ. Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats. Diabetes. 57: 614-22. PMID 18086903 DOI: 10.2337/Db07-0863  0.562
2007 Tümer N, Erdös B, Matheny M, Cudykier I, Scarpace PJ. Leptin antagonist reverses hypertension caused by leptin overexpression, but fails to normalize obesity-related hypertension. Journal of Hypertension. 25: 2471-8. PMID 17984669 DOI: 10.1097/Hjh.0B013E3282E9A9Fd  0.446
2007 Erdös B, Broxson CS, Landa T, Scarpace PJ, Leeuwenburgh C, Zhang Y, Tümer N. Effects of life-long caloric restriction and voluntary exercise on age-related changes in levels of catecholamine biosynthetic enzymes and angiotensin II receptors in the rat adrenal medulla and hypothalamus. Experimental Gerontology. 42: 745-52. PMID 17540525 DOI: 10.1016/J.Exger.2007.04.007  0.406
2007 Li G, Zhang Y, Cheng KY, Scarpace PJ. Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central melanocortin responsiveness Diabetologia. 50: 1490-1499. PMID 17505816 DOI: 10.1007/S00125-007-0685-1  0.623
2007 Scarpace PJ, Zhang Y. Elevated leptin: consequence or cause of obesity? Frontiers in Bioscience : a Journal and Virtual Library. 12: 3531-44. PMID 17485319 DOI: 10.2741/2332  0.49
2007 Li G, Zhang Y, Rodrigues E, Zheng D, Matheny M, Cheng KY, Scarpace PJ. Melanocortin activation of nucleus of the solitary tract avoids anorectic tachyphylaxis and induces prolonged weight loss. American Journal of Physiology. Endocrinology and Metabolism. 293: E252-8. PMID 17389713 DOI: 10.1152/Ajpendo.00451.2006  0.541
2007 Scarpace PJ, Matheny M, Zhang Y, Cheng KY, Tümer N. Leptin antagonist reveals an uncoupling between leptin receptor signal transducer and activator of transcription 3 signaling and metabolic responses with central leptin resistance. The Journal of Pharmacology and Experimental Therapeutics. 320: 706-12. PMID 17082312 DOI: 10.1124/Jpet.106.112813  0.534
2007 Zhang J, Matheny MK, Tümer N, Mitchell MK, Scarpace PJ. Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R868-74. PMID 17023670 DOI: 10.1152/Ajpregu.00213.2006  0.816
2006 Zhang Y, Scarpace PJ. The role of leptin in leptin resistance and obesity. Physiology & Behavior. 88: 249-56. PMID 16782141 DOI: 10.1016/J.Physbeh.2006.05.038  0.441
2006 Zhang Y, Scarpace PJ. Circumventing central leptin resistance: lessons from central leptin and POMC gene delivery. Peptides. 27: 350-64. PMID 16274846 DOI: 10.1016/J.Peptides.2005.01.024  0.503
2006 Wilsey J, Matheny MK, Scarpace PJ. Oral vanadium enhances the catabolic effects of central leptin in young adult rats. Endocrinology. 147: 493-501. PMID 16195403 DOI: 10.1210/En.2004-1358  0.764
2006 Tümer N, Scarpace PJ, Dogan MD, Broxson CS, Matheny M, Yurek DM, Peden CS, Burger C, Muzyczka N, Mandel RJ. Hypothalamic rAAV-mediated GDNF gene delivery ameliorates age-related obesity. Neurobiology of Aging. 27: 459-70. PMID 15964099 DOI: 10.1016/J.Neurobiolaging.2005.03.018  0.557
2006 Aslanidi G, Philipsberg G, Kroutov V, Lamb K, Kohlbrenner E, Campbell-Thompson M, Walter G, Scarpace PJ, Zolotukhin S. 406. rAAV-Mediated Expression of Wnt10b cDNA Prevents the Development of Obesity in DIO Rats Molecular Therapy. 13: S156. DOI: 10.1016/J.Ymthe.2006.08.469  0.381
2005 Li G, Zhang Y, Wilsey JT, Scarpace PJ. Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats. Diabetologia. 48: 2376-85. PMID 16205885 DOI: 10.1007/S00125-005-1943-8  0.782
2005 Scarpace PJ, Matheny M, Tümer N, Cheng KY, Zhang Y. Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats Diabetologia. 48: 1075-1083. PMID 15864530 DOI: 10.1007/S00125-005-1763-X  0.571
2004 Zhang Y, Matheny M, Tümer N, Scarpace PJ. Aged-obese rats exhibit robust responses to a melanocortin agonist and antagonist despite leptin resistance. Neurobiology of Aging. 25: 1349-60. PMID 15465633 DOI: 10.1016/J.Neurobiolaging.2004.02.012  0.543
2004 Li G, Zhang Y, Wilsey JT, Scarpace PJ. Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression. The Journal of Endocrinology. 182: 123-32. PMID 15225137 DOI: 10.1677/Joe.0.1820123  0.8
2004 Wilsey J, Scarpace PJ. Caloric restriction reverses the deficits in leptin receptor protein and leptin signaling capacity associated with diet-induced obesity: Role of leptin in the regulation of hypothalamic long-form leptin receptor expression Journal of Endocrinology. 181: 297-306. PMID 15128278 DOI: 10.1677/Joe.0.1810297  0.537
2004 Prima V, Tennant M, Gorbatyuk OS, Muzyczka N, Scarpace PJ, Zolotukhin S. Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: microarray deoxyribonucleic acid-chip analysis of gene expression. Endocrinology. 145: 2035-45. PMID 14715713 DOI: 10.1210/En.2003-1376  0.5
2003 Shklyaev S, Aslanidi G, Tennant M, Prima V, Kohlbrenner E, Kroutov V, Campbell-Thompson M, Crawford J, Shek EW, Scarpace PJ, Zolotukhin S. Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats. Proceedings of the National Academy of Sciences of the United States of America. 100: 14217-22. PMID 14617771 DOI: 10.1073/Pnas.2333912100  0.487
2003 Wilsey J, Zolotukhin S, Prima V, Scarpace PJ. Central leptin gene therapy fails to overcome leptin resistance associated with diet-induced obesity. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R1011-20. PMID 14557234 DOI: 10.1152/Ajpregu.00193.2003  0.812
2003 Li G, Mobbs CV, Scarpace PJ. Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats. Diabetes. 52: 1951-7. PMID 12882910 DOI: 10.2337/Diabetes.52.8.1951  0.567
2003 Scarpace PJ, Matheny M, Zolotukhin S, Tümer N, Zhang Y. Leptin-induced leptin resistant rats exhibit enhanced responses to the melanocortin agonist MT II. Neuropharmacology. 45: 211-9. PMID 12842127 DOI: 10.1016/S0028-3908(03)00158-8  0.537
2003 Kim YW, Scarpace PJ. Repeated fasting/refeeding elevates plasma leptin without increasing fat mass in rats. Physiology & Behavior. 78: 459-64. PMID 12676282 DOI: 10.1016/S0031-9384(03)00016-7  0.56
2002 Li G, Klein RL, Matheny M, King MA, Meyer EM, Scarpace PJ. Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in rats. Neuroscience. 115: 879-89. PMID 12435426 DOI: 10.1016/S0306-4522(02)00447-5  0.409
2002 Wilsey J, Zolotukhin S, Prima V, Shek EW, Matheny MK, Scarpace PJ. Hypothalmic delivery of doxycycline-inducible leptin gene allows for reversible transgene expression and physiological responses Gene Therapy. 9: 1492-1499. PMID 12407421 DOI: 10.1038/Sj.Gt.3301835  0.792
2002 Zhang Y, Matheny M, Zolotukhin S, Tumer N, Scarpace PJ. Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting. Biochimica Et Biophysica Acta. 1584: 115-22. PMID 12385894 DOI: 10.1016/S1388-1981(02)00298-6  0.439
2002 Zhang Y, Wilsey JT, Frase CD, Matheny MM, Bender BS, Zolotukhin S, Scarpace PJ. Peripheral but not central leptin prevents the immunosuppression associated with hypoleptinemia in rats. The Journal of Endocrinology. 174: 455-61. PMID 12208666 DOI: 10.1677/Joe.0.1740455  0.797
2002 Scarpace PJ, Matheny M, Zhang Y, Shek EW, Prima V, Zolotukhin S, Tümer N. Leptin-induced leptin resistance reveals separate roles for the anorexic and thermogenic responses in weight maintenance. Endocrinology. 143: 3026-35. PMID 12130569 DOI: 10.1210/Endo.143.8.8966  0.514
2002 Scarpace PJ, Matheny M, Zhang Y, Tümer N, Frase CD, Shek EW, Hong B, Prima V, Zolotukhin S. Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats Neuropharmacology. 42: 548-561. PMID 11955525 DOI: 10.1016/S0028-3908(02)00003-5  0.606
2002 Borst SE, Snellen HG, Ross H, Scarpace PJ, Kim YW. Metformin restores responses to insulin but not to growth hormone in Sprague-Dawley rats. Biochemical and Biophysical Research Communications. 291: 722-6. PMID 11855850 DOI: 10.1006/Bbrc.2002.6498  0.438
2001 Scarpace PJ, Tümer N. Peripheral and hypothalamic leptin resistance with age-related obesity Physiology and Behavior. 74: 721-727. PMID 11790435 DOI: 10.1016/S0031-9384(01)00616-3  0.569
2001 Scarpace PJ, Matheny M, Tümer N. Hypothalamic leptin resistance is associated with impaired leptin signal transduction in aged obese rats Neuroscience. 104: 1111-1117. PMID 11457594 DOI: 10.1016/S0306-4522(01)00142-7  0.573
2001 Dhillon H, Kalra SP, Prima V, Zolotukhin S, Scarpace PJ, Moldawer LL, Muzyczka N, Kalra PS. Central leptin gene therapy suppresses body weight gain, adiposity and serum insulin without affecting food consumption in normal rats: a long-term study. Regulatory Peptides. 99: 69-77. PMID 11384767 DOI: 10.1016/S0167-0115(01)00237-3  0.521
2001 Koller MM, Cowman RA, Humphreys-Beher MG, Scarpace PJ. An analysis of parotid salivary gland function with desipramine and age in female NIA Fischer 344 rats Experimental Gerontology. 36: 141-157. PMID 11162918 DOI: 10.1016/S0531-5565(00)00188-1  0.394
2000 Koller MM, Purushotham KR, Maeda N, Scarpace PJ, Humphreys-Beher MG. Desipramine induced changes in salivary proteins, cultivable oral microbiota and gingival health in aging female NIA Fischer 344 rats Life Sciences. 68: 445-455. PMID 11205893 DOI: 10.1016/S0024-3205(00)00951-6  0.388
2000 Scarpace PJ, Kumar MV, Li H, Tümer N. Uncoupling proteins 2 and 3 with age: Regulation by fasting and β3-adrenergic agonist treatment Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 55. PMID 11129388 DOI: 10.1093/Gerona/55.12.B588  0.444
2000 Koller MM, Cowman RA, Humphreys-Beher MG, Scarpace PJ. An analysis of submandibular salivary gland function with desipramine and age in female NIA Fischer 344 rats Mechanisms of Ageing and Development. 119: 131-147. PMID 11080533 DOI: 10.1016/S0047-6374(00)00176-7  0.408
2000 Koller MM, Maeda N, Scarpace PJ, Humphreys-Beher MG. Desipramine changes salivary gland function, oral microbiota, and oral health in rats European Journal of Pharmacology. 408: 91-98. PMID 11070187 DOI: 10.1016/S0014-2999(00)00770-6  0.311
2000 Shek EW, Scarpace PJ. Resistance to the anorexic and thermogenic effects of centrally administrated leptin in obese aged rats Regulatory Peptides. 92: 65-71. PMID 11024567 DOI: 10.1016/S0167-0115(00)00151-8  0.467
2000 Scarpace PJ, Matheny M, Shek EW. Impaired leptin signal transduction with age-related obesity Neuropharmacology. 39: 1872-1879. PMID 10884568 DOI: 10.1016/S0028-3908(00)00014-9  0.524
2000 Scarpace PJ, Matheny M, Moore RL, Tümer N. Impaired leptin responsiveness in aged rats. Diabetes. 49: 431-5. PMID 10868965 DOI: 10.2337/Diabetes.49.3.431  0.562
2000 Scarpace PJ, Matheny M, Moore RL, Kumar MV. Modulation of uncoupling protein 2 and uncoupling protein 3: regulation by denervation, leptin and retinoic acid treatment. The Journal of Endocrinology. 164: 331-7. PMID 10694373 DOI: 10.1677/Joe.0.1640331  0.314
2000 Scarpace PJ, Tümer N. Leptin resistance with age-related obesity Rejuvenation Research. 3: 183-189. DOI: 10.1089/Rej.1.2000.3.183  0.59
1999 Tümer N, Broxson CS, LaRochelle JS, Scarpace PJ. Induction of tyrosine hydroxylase and neuropeptide Y by carbachol: Modulation with age Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 54. PMID 10568524 DOI: 10.1093/Gerona/54.10.B418  0.4
1999 Kumar MV, Moore RL, Scarpace PJ. Beta3-adrenergic regulation of leptin, food intake, and adiposity is impaired with age. PflüGers Archiv : European Journal of Physiology. 438: 681-8. PMID 10555566 DOI: 10.1007/s004240051093  0.498
1999 Kumar MV, Sunvold GD, Scarpace PJ. Dietary vitamin A supplementation in rats: Suppression of leptin and induction of UCP1 mRNA Journal of Lipid Research. 40: 824-829. PMID 10224151  0.334
1999 Scarpace PJ, Matheny M, Tümer N. Differential down-regulation of β3-adrenergic receptor mRNA and signal transduction by cold exposure in brown adipose tissue of young and senescent rats Pflugers Archiv European Journal of Physiology. 437: 479-483. PMID 9914406 DOI: 10.1007/S004240050804  0.426
1998 Li H, Matheny M, Tümer N, Scarpace PJ. Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression. American Journal of Physiology. Endocrinology and Metabolism. 275: E405-E411. PMID 29585554 DOI: 10.1152/ajpendo.1998.275.3.E405  0.382
1998 Scarpace PJ, Matheny M. Leptin induction of UCP1 gene expression is dependent on sympathetic innervation. American Journal of Physiology. Endocrinology and Metabolism. 275: E259-E264. PMID 29585186 DOI: 10.1152/ajpendo.1998.275.2.E259  0.364
1998 Scarpace PJ, Nicolson M, Matheny M. UCP2, UCP3 and leptin gene expression: Modulation by food restriction and leptin Journal of Endocrinology. 159: 349-357. PMID 9795377 DOI: 10.1677/Joe.0.1590349  0.434
1998 Li H, Matheny M, Tümer N, Scarpace PJ. Aging and fasting regulation of leptin and hypothalamic neuropeptide Y gene expression American Journal of Physiology - Endocrinology and Metabolism. 275. PMID 9725806 DOI: 10.1152/Ajpendo.1998.275.3.E405  0.482
1998 Scarpace PJ, Matheny M. Leptin induction of UCP1 gene expression is dependent on sympathetic innervation American Journal of Physiology - Endocrinology and Metabolism. 275. PMID 9688627 DOI: 10.1152/Ajpendo.1998.275.2.E259  0.466
1997 Li H, Matheny M, Nicolson M, Tümer N, Scarpace PJ. Leptin gene expression increases with age independent of increasing adiposity in rats Diabetes. 46: 2035-2039. PMID 9392492  0.37
1997 Tümer N, Scarpace PJ, Baker HV, Larochelle JS. AP-1 transcription factor binding activity in rat adrenal medulla and hypothalamus with age and cold exposure Neuropharmacology. 36: 1065-1069. PMID 9294971 DOI: 10.1016/S0028-3908(97)00093-2  0.394
1997 Scarpace PJ, Matheny M, Pollock BH, Tümer N. Leptin increases uncoupling protein expression and energy expenditure American Journal of Physiology - Endocrinology and Metabolism. 273. PMID 9252501 DOI: 10.1152/Ajpendo.1997.273.1.E226  0.495
1997 Li H, Matheny M, Scarpace PJ. β3-Adrenergic-mediated suppression of leptin gene expression in rats American Journal of Physiology - Endocrinology and Metabolism. 272. PMID 9227448 DOI: 10.1152/Ajpendo.1997.272.6.E1031  0.441
1997 Tümer N, Bowman CJ, LaRochelle JS, Kelley A, Scarpace PJ. Induction of tyrosine hydroxylase by forskolin: Modulation with age European Journal of Pharmacology. 324: 57-62. PMID 9137913 DOI: 10.1016/S0014-2999(97)00055-1  0.421
1997 Scarpace PJ. Thermoregulation with age: Role of beta-adrenergic signal transduction Annals of the New York Academy of Sciences. 813: 111-116. PMID 9100870 DOI: 10.1111/J.1749-6632.1997.Tb51680.X  0.417
1997 Scarpace PJ, Matheny M. Leptin increases uncoupling protein expression in brown adiplse tissue along with energy expenditure Faseb Journal. 11.  0.347
1996 Tümer N, Sego RL, Scarpace PJ. Atypical pattern of adenylyl cyclase activity in the adrenal medulla with age Experimental Gerontology. 31: 571-576. PMID 9415112 DOI: 10.1016/0531-5565(96)00053-8  0.399
1996 Scarpace PJ, Dove J, Matheny M. Effects of age on β adrenergic subtype activation of adenylyl cyclase in brown adipose tissue Proceedings of the Society For Experimental Biology and Medicine. 213: 262-267. PMID 8985310 DOI: 10.3181/00379727-213-44058  0.328
1996 Scarpace PJ, Matheny M, Tümer N. Myocardial adenylyl cyclase type V and VI mRNA: Differential regulation with age Journal of Cardiovascular Pharmacology. 27: 86-90. PMID 8656664 DOI: 10.1097/00005344-199601000-00014  0.337
1996 Scarpace PJ, Tse C, Matheny M. Thermoregulation with age: Restoration of β3-adrenergic responsiveness in brown adipose tissue by cold exposure Proceedings of the Society For Experimental Biology and Medicine. 211: 374-380. PMID 8618944 DOI: 10.3181/00379727-211-43983  0.425
1996 Scarpace PJ, Matheny M. Thermogenesis in brown adipose tissue with age: Post-receptor activation by forskolin PflüGers Archiv European Journal of Physiology. 431: 388-394. PMID 8584432 DOI: 10.1007/Bf02207276  0.477
1994 Borst SE, Oliver RJ, Scarpace PJ. Alpha1-adrenergic and arginine vasopressin stimulation of inositide hydrolysis in rat hepatocytes is unaltered in senescence Journals of Gerontology. 49. PMID 8282972 DOI: 10.1093/Geronj/49.1.B18  0.343
1994 Scarpace PJ, Matheny M, Borst S, Tümer N. Thermoregulation with Age: Role of Thermogenesis and Uncoupling Protein Expression in Brown Adipose Tissue Proceedings of the Society For Experimental Biology and Medicine. 205: 154-161. PMID 8108465 DOI: 10.3181/00379727-205-43691  0.44
1994 Rajakumar G, Scarpace PJ. Relationship between cAMP production and protein secretion in rat submandibular acini: Evidence for loss of reserve capacity with age Life Sciences. 55: 761-766. PMID 8072373 DOI: 10.1016/0024-3205(94)00559-1  0.385
1994 Sanghani MP, Scarpace PJ. Atypical β-adrenergic receptors in rat liver: Evidence for transient expression during aging Journals of Gerontology. 49. PMID 7907351 DOI: 10.1093/Geronj/49.2.B60  0.336
1994 Scarpace PJ, Yenice S, Tümer N. Influence of exercise training and age on uncoupling protein mRNA expression in brown adipose tissue Pharmacology, Biochemistry and Behavior. 49: 1057-1059. PMID 7886075 DOI: 10.1016/0091-3057(94)90264-X  0.354
1994 Borst SE, Oliver RJ, Sego RL, Scarpace PJ. α-Adrenergic receptor-mediated thermogenesis in brown adipose tissue of rat General Pharmacology. 25: 1703-1710. PMID 7721049 DOI: 10.1016/0306-3623(94)90375-1  0.333
1994 Shu Y, Scarpace PJ. Forskolin binding sites and G-protein immunoreactivity in rat hearts during aging Journal of Cardiovascular Pharmacology. 2: 188-193. PMID 7511746 DOI: 10.1097/00005344-199402000-00003  0.403
1993 Crass MF, Scarpace PJ. Vasoactive properties of a parathyroid hormone-related protein in the rat aorta Peptides. 14: 179-183. PMID 8387185 DOI: 10.1016/0196-9781(93)90027-E  0.352
1993 Scarpace PJ, Koller MM, Rajakumar G. Desipramine desensitizes β-adrenergic signal transduction in salivary glands: differential regulation with age European Journal of Pharmacology: Molecular Pharmacology. 247: 65-72. PMID 8258362 DOI: 10.1016/0922-4106(93)90138-Y  0.433
1993 Mooradian AD, Scarpace PJ. 3,5,3′-l-Triiodothyronine regulation of β-adrenergic receptor density and adenylyl cyclase activity in synaptosomal membranes of aged rats Neuroscience Letters. 161: 101-104. PMID 8255534 DOI: 10.1016/0304-3940(93)90150-J  0.435
1992 Scarpace PJ, Borst SE, Bender BS. The association of E. coli peritonitis with an impaired and delayed fever response in senescent rats Journals of Gerontology. 47. PMID 1624691 DOI: 10.1093/Geronj/47.4.B142  0.408
1992 Scarpace PJ, Matheny M, Bender BS, Borst SE. Impaired Febrile Response with Age: Role of Thermogenesis in Brown Adipose Tissue (43442) Proceedings of the Society For Experimental Biology and Medicine. 200: 353-358. PMID 1615011 DOI: 10.3181/00379727-200-43442  0.42
1992 Scarpace PJ, Matheny M, Borst SE. Thermogenesis and mitochondrial GDP binding with age in response to the novel agonist CGP-12177A American Journal of Physiology - Endocrinology and Metabolism. 262. PMID 1539643 DOI: 10.1152/Ajpendo.1992.262.2.E185  0.395
1992 Koller MM, Maeda N, Purushotham KR, Scarpace PJ, Humphreys-Beher MG. A biochemical analysis of parotid and submandibular salivary gland function with age after simultaneous stimulation with pilocarpine and isoproterenol in female NIA Fischer 344 rats Archives of Oral Biology. 37: 219-230. PMID 1375022 DOI: 10.1016/0003-9969(92)90092-M  0.303
1992 Scarpace PJ, Koller MM, Rajakumar G. Desipramine desensitizes β-adrenergic signal transduction in rat salivary glands Neuropharmacology. 31: 1305-1309. PMID 1335132 DOI: 10.1016/0028-3908(92)90060-3  0.389
1992 Scarpace PJ, Lowenthal DT, Tümer N. Influence of exercise and age on myocardial β-adrenergic receptor properties Experimental Gerontology. 27: 169-177. PMID 1325922 DOI: 10.1016/0531-5565(92)90041-W  0.348
1992 Mooradian AD, Scarpace PJ. β-Adrenergic receptor activity of cerebral microvessels in experimental diabetes mellitus Brain Research. 583: 155-160. PMID 1324092 DOI: 10.1016/S0006-8993(10)80019-8  0.343
1992 Crass MF, Borst SE, Scarpace PJ. β-adrenergic responsiveness in cultured aorta smooth muscle cells Effects of subculture and aging Biochemical Pharmacology. 43: 1811-1815. PMID 1315546 DOI: 10.1016/0006-2952(92)90714-T  0.368
1991 Mooradian AD, Scarpace PJ. β-Adrenergic receptor activity of cerebral microvessels is reduced in aged rats Neurochemical Research. 16: 447-451. PMID 1681437 DOI: 10.1007/Bf00965565  0.395
1991 Scarpace PJ, Turner N, Mader SL. β-Adrenergic Function in Aging: Basic Mechanisms and Clinical Implications Drugs &Amp; Aging. 1: 116-129. PMID 1665371 DOI: 10.2165/00002512-199101020-00004  0.396
1991 Rajakumar G, Scarpace PJ. β-Adrenergic signal transduction in aging parotid and submandibular salivary glands Journals of Gerontology. 46. PMID 1658113 DOI: 10.1093/Geronj/46.6.B249  0.356
1991 Scarpace PJ, Bender BS, Borst SE. Escherichia coli peritonitis activates thermogenesis in brown adipose tissue: Relationship to fever Canadian Journal of Physiology and Pharmacology. 69: 761-766. PMID 1655179 DOI: 10.1139/Y91-113  0.349
1990 Borst SE, Scarpace PJ. Alpha1-adrenergic stimulation of inositide hydrolysis in liver of senescent rats Mechanisms of Ageing and Development. 56: 275-280. PMID 1965214 DOI: 10.1016/0047-6374(90)90088-W  0.381
1990 Borst SE, Scarpace PJ. Reduced high-affinity α1-adrenoceptors in liver of senescent rats: Implications of assessment at various temperatures British Journal of Pharmacology. 101: 650-654. PMID 1963803 DOI: 10.1111/J.1476-5381.1990.Tb14135.X  0.347
1990 Borst SE, Narang N, Crews FT, Scarpace PJ. Reduced alpha 1-adrenergic receptor-mediated inositide hydrolysis in cardiac atria of senescent rats. Journal of Cardiovascular Pharmacology. 16: 444-8. PMID 1700216 DOI: 10.1097/00005344-199009000-00014  0.4
1988 Mooradian AD, Morley JE, Scarpace PJ. The role of zinc status in altered cardiac adenylate cyclase activity in diabetic rats Acta Endocrinologica. 119: 174-180. PMID 2845690 DOI: 10.1530/Acta.0.1190174  0.373
1988 Scarpace PJ, Mooradian AD, Morley JE. Age-associated decrease in beta-adrenergic receptors and adenylate cyclase activity in rat brown adipose tissue Journals of Gerontology. 43. PMID 2834431  0.341
1981 Scarpace PJ, Abrass IB. Thyroid hormone regulation of β-adrenergic receptor number in aging rats Endocrinology. 108: 1276-1278. PMID 6258903 DOI: 10.1210/Endo-108-4-1276  0.43
1981 Abrass IB, Scarpace PJ. Glucocorticoid regulation of myocardial β-adrenergic receptors Endocrinology. 108: 977-980. PMID 6257502 DOI: 10.1210/Endo-108-3-977  0.336
1981 Scarpace PJ, Abrass IB. Thyroid hormone regulation of rat heart, lymphocyte, and lung β-adrenergic receptors Endocrinology. 108: 1007-1011. PMID 6257494 DOI: 10.1210/Endo-108-3-1007  0.337
Low-probability matches (unlikely to be authored by this person)
1983 Scarpace PJ, Abrass IB. Decreased beta-adrenergic agonist affinity and adenylate cyclase activity in senescent rat lung Journals of Gerontology. 38: 143-147. PMID 6298302 DOI: 10.1093/Geronj/38.2.143  0.3
2017 Bruce E, Carter C, Sakarya Y, Toklu H, Morgan D, Scarpace P, Tumer N. EXACERBATED AGE-RELATED OBESITY IS TEMPERED BY RENIN ANGIOTENSIN SYSTEM Innovation in Aging. 1: 580-580. DOI: 10.1093/Geroni/Igx004.2038  0.298
1986 Scarpace PJ, Abrass IB. Beta-adrenergic agonist-mediated desensitization in senescent rats Mechanisms of Ageing and Development. 35: 255-264. PMID 2877123 DOI: 10.1016/0047-6374(86)90128-4  0.295
1990 Scarpace PJ. Forskolin activation of adenylate cyclase in rat myocardium with age: Effects of guanine nucleotide analogs Mechanisms of Ageing and Development. 52: 169-178. PMID 2325432 DOI: 10.1016/0047-6374(90)90122-V  0.294
1989 Mooradian AD, Scarpace PJ. The response to isoproterenol-stimulated adenylate cyclase activity after administration of L-triiodothyronine is reduced in aged rats Hormone and Metabolic Research. 21: 638-639. PMID 2591880  0.294
1992 Tumer N, Scarpace PJ, Lowenthal DT. Geriatric pharmacology: Basic and clinical considerations Annual Review of Pharmacology and Toxicology. 32: 271-302. PMID 1605569 DOI: 10.1146/Annurev.Pa.32.040192.001415  0.288
1981 O'Connor SW, Scarpace PJ, Abrass IB. Age-associated decrease of adenylate cyclase activity in rat myocardium Mechanisms of Ageing and Development. 16: 91-95. PMID 6265716 DOI: 10.1016/0047-6374(81)90036-1  0.287
2015 Toklu HZ, Muller-Delp J, Yang Z, Oktay ?, Sakarya Y, Strang K, Ghosh P, Delp MD, Scarpace PJ, Wang KK, Tümer N. The functional and structural changes in the basilar artery due to overpressure blast injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26104291 DOI: 10.1038/Jcbfm.2015.151  0.285
2015 Anton SD, Woods AJ, Ashizawa T, Barb D, Buford TW, Carter CS, Clark DJ, Cohen RA, Corbett DB, Cruz-Almeida Y, Dotson V, Ebner N, Efron PA, Fillingim RB, Foster TC, ... ... Scarpace PJ, et al. Successful aging: Advancing the science of physical independence in older adults. Ageing Research Reviews. PMID 26462882 DOI: 10.1016/J.Arr.2015.09.005  0.282
1983 O'Connor SW, Scarpace PJ, Abrass IB. Age-associated decrease in the catalytic unit activitiy of rat myocardial adenylate cyclase Mechanisms of Ageing and Development. 21: 357-363. PMID 6310279 DOI: 10.1016/0047-6374(83)90052-0  0.281
2014 Cuenca AG, Cuenca AL, Winfield RD, Joiner DN, Gentile L, Delano MJ, Kelly-Scumpia KM, Scumpia PO, Matheny MK, Scarpace PJ, Vila L, Efron PA, LaFace DM, Moldawer LL. Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia. Journal of Immunology (Baltimore, Md. : 1950). 192: 6111-9. PMID 24829407 DOI: 10.4049/Jimmunol.1302895  0.28
1982 Scarpace PJ, Abrass IB. Age dependent decrease in agonist affinity and adenylate cyclase activity in rat lung Age. 5: 135.  0.279
1988 Scarpace PJ. Decreased receptor activation with age. Can it be explained by desensitization? Journal of the American Geriatrics Society. 36: 1067-1071. PMID 2844878  0.278
1994 Cowman RA, Frisch M, Lasseter CJ, Scarpace PJ. Effects of beta-adrenergic antagonists on salivary secretory function in individuals of different ages. Journal of Gerontology. 49: B208-14. PMID 7914526 DOI: 10.1093/Geronj/49.5.B208  0.276
2002 Scarpace PJ, Matheny M, Zhang Y, Shek EW, Prima V, Zolotukhin S, Tu Mer N. Leptin-Induced Leptin Resistance Reveals Separate Roles for the Anorexic and Thermogenic Responses in Weight Maintenance. Endocrinology. 143: 3026-3035. PMID 28201689 DOI: 10.1210/endo.143.8.8966  0.272
2012 Carter CS, Marzetti E, Leeuwenburgh C, Manini T, Foster TC, Groban L, Scarpace PJ, Morgan D. Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 67: 17-27. PMID 21636833 DOI: 10.1093/Gerona/Glr042  0.27
1982 Abrass IB, Davis JL, Scarpace PJ. Isoproterenol responsiveness and myocardial β-adrenergic receptors in young and old rats Journals of Gerontology. 37: 156-160. PMID 6276461  0.269
1982 Tashkin DP, Conolly ME, Deutsch RI, Hui KK, Littner M, Scarpace P, Abrass I. Subsensitization of beta-adrenoceptors in airways and lymphocytes of healthy and asthmatic subjects. The American Review of Respiratory Disease. 125: 185-93. PMID 6278998 DOI: 10.1164/Arrd.1982.125.2.185  0.264
1979 Scarpace PJ, Abrass IB. Beta-adrenergic receptors in aged rats Federation Proceedings. 38.  0.259
2001 Vincent HK, Powers SK, Dirks AJ, Scarpace PJ. Mechanism for obesity-induced increase in myocardial lipid peroxidation International Journal of Obesity. 25: 378-388. PMID 11319636 DOI: 10.1038/sj.ijo.0801536  0.258
1986 Scarpace PJ. Decreased β-adrenergic responsiveness during senescence Federation Proceedings. 45: 51-54. PMID 3000835  0.257
2017 Toklu HZ, Yang Z, Oktay S, Sakarya Y, Kirichenko N, Matheny MK, Muller-Delp J, Strang K, Scarpace PJ, Wang KKW, Tümer N. Overpressure blast injury-induced oxidative stress and neuroinflammation response in rat frontal cortex and cerebellum. Behavioural Brain Research. PMID 28419850 DOI: 10.1016/J.Bbr.2017.04.025  0.255
1987 Scarpace PJ, Baresi LA, Morley JE. Modulation of receptors and adenylate cyclase activity during sucrose feeding, food deprivation, and cold exposure American Journal of Physiology - Endocrinology and Metabolism. 253. PMID 2827501  0.254
1998 Scarpace PJ, Matheny M, Tümer N. Cold preferentially down regulates β3-adrenergic receptor mRNA and signal transduction in brown adipose tissue of young compared with senescent rats Faseb Journal. 12.  0.252
1988 Scarpace PJ, Baresi LA, Morley JE. Glucocorticoids modulate β-adrenoceptor subtypes and adenylate cyclase in brown fat American Journal of Physiology - Endocrinology and Metabolism. 255. PMID 2841864  0.25
1992 Rajakumar G, Koller MM, Scarpace PJ. β-adrenergic receptors and salivary gland secretion during aging Growth, Development and Aging. 56: 215-223. PMID 1336769  0.25
1987 Scarpace PJ. Characterization of beta‐adrenergic receptors throughout the replicative life span of IMR‐90 cells Journal of Cellular Physiology. 130: 163-167. PMID 3027107 DOI: 10.1002/jcp.1041300123  0.249
2006 Erdös B, Broxson CS, King MA, Scarpace PJ, Tümer N. Acute pressor effect of central angiotensin II is mediated by NAD(P)H-oxidase-dependent production of superoxide in the hypothalamic cardiovascular regulatory nuclei. Journal of Hypertension. 24: 109-16. PMID 16331108 DOI: 10.1097/01.Hjh.0000198026.99600.59  0.248
2008 Zhang J, Scarpace PJ. Soluble leptin receptor neutralizes leptin signaling and anorexic responses The Faseb Journal. 22: 658-658. DOI: 10.1096/fasebj.22.2_supplement.658  0.243
1994 Scarpace PJ, Shu Y, Tumer N. Influence of exercise training on myocardial β-adrenergic signal transduction: Differential regulation with age Journal of Applied Physiology. 77: 737-741. PMID 8002522  0.24
1977 Scarpace PJ, Neuman WF, Raisz LG. Metabolism of radioiodinated salmon calcitonin in rats Endocrinology. 100: 1260-1267. PMID 849723 DOI: 10.1210/Endo-100-5-1260  0.228
1984 O'Connor SW, Scarpace PJ, Abrass IB. The effect of age and cholesterol on the rat lung beta-adrenergic system Bba - Biomembranes. 778: 497-502. PMID 6095909 DOI: 10.1016/0005-2736(84)90399-7  0.226
1982 Scarpace PJ, Abrass IB. Desensitization of adenylate cyclase and down regulation of beta adrenergic receptors after in vivo administration of beta agonist Journal of Pharmacology and Experimental Therapeutics. 223: 327-331. PMID 6127402  0.221
1985 Abrass CK, O'Connor SW, Scarpace PJ, Abrass IB. Characterization of the β-adrenergic receptor of the rat peritoneal macrophage Journal of Immunology. 135: 1338-1341. PMID 2409147  0.219
1975 Scarpace PJ, Neuman WF. Distribution and metabolism of 125I salmon calcitonin in young and old rats Physiologist. 18: 380.  0.216
1996 Scarpace PJ, Dove J, Mathenv M. Effect of age on beta-adreneroic subtype activation of adenylyl cyclase in brown adipose tissue Faseb Journal. 10.  0.215
1982 Scarpace PJ, Abrass IB. Glucocorticoid regulation of lung beta‐adrenergic receptors Drug Development Research. 2: 91-94. DOI: 10.1002/ddr.430020113  0.212
1987 Scarpace PJ, Byung Pal Yu. Diet restriction retards the age-related loss of beta-adrenergic receptors and adenylate cyclase activity in rat lung Journals of Gerontology. 42: 442-446. PMID 3036931  0.204
1993 Bender BS, Bell WE, Taylor S, Scarpace PJ. Decreased sensitivity to cAMP in the in vitro generation of memory splenic cytotoxic T-lymphocytes from aged mice: Role of phosphodiesterase Journal of Pharmacology and Experimental Therapeutics. 264: 1381-1386. PMID 8383747  0.2
1985 Scarpace PJ, O'Connor SW, Abrass IB. Cholesterol modulation of β-adrenergic receptor characteristics Bba - Molecular Cell Research. 845: 520-525. PMID 2988644 DOI: 10.1016/0167-4889(85)90220-4  0.197
1977 Scarpace PJ, Deftos LJ. The immunological characteristics and metabolic distribution in rats of biologically active and inactive human calcitonin Federation Proceedings. 36.  0.19
1982 Abrass IB, Scarpace PJ. Catalytic unit of adenylate cyclase: Reduced activity in aged-human lymphocytes Journal of Clinical Endocrinology and Metabolism. 55: 1026-1028. PMID 6889610  0.186
1988 Mader SL, Robbins AS, Rubenstein LZ, Tuck ML, Scarpace PJ. Effect of age and posture on human lymphocyte adenylate cyclase activity Clinical Science. 74: 331-334. PMID 3345640  0.185
1998 Kumar MV, Scarpace PJ. Differential effects of retinoic acid on uncoupling protein-1 and leptin gene expression Journal of Endocrinology. 157: 237-243. PMID 9659286 DOI: 10.1677/joe.0.1570237  0.182
2011 Shapiro A, Strehler K, Ryder D, Tumer N, Scarpace P. Fructose-induced leptin resistance involves impaired AMPK but intact STAT3 signaling Appetite. 57: S40. DOI: 10.1016/j.appet.2011.05.269  0.176
1988 Scarpace PJ, Baresi LA. Increased beta-adrenergic receptors in the light-density membrane fraction in lungs from senescent rats Journals of Gerontology. 43. PMID 2846681  0.175
1977 Scarpace PJ, Deftos LJ. Preparation and immunological characteristics of biologically active radioiodinated human calcitonin Endocrinology. 101: 1398-1405. PMID 199416  0.174
1997 Kumar MV, Scarpace PJ. Differential effects of retinoic acid on uncoupling protein and leptin gene expression Faseb Journal. 11.  0.169
1981 Abrass IB, Scarpace PJ. Human lymphocyte beta-adrenergic receptors are unaltered with age Journals of Gerontology. 36: 298-301. PMID 6262399  0.167
1978 Scarpace PJ, Abrass IB. Identification of β-adrenergic receptors in rat lung membranes: model system for testing the hypothesis of glucocorticoid reversal of β-blockade Federation Proceedings. 37.  0.166
1978 Abrass IB, Scarpace PJ. Lymphocyte β-adrenergic receptors in aging males Gerontologist. 18: 43.  0.164
1990 Scarpace PJ, Matheny M. The putative β-adrenergic antagonist CGP-12177 activates adenylate cyclase in brown adipose tissue but not in heart European Journal of Pharmacology. 183: 2164-2165. DOI: 10.1016/0014-2999(90)93690-R  0.161
1985 Scarpace PJ, Baresi LA, Sanford DA, Abrass IB. Desensitization and resensitization of β-adrenergic receptors in a smooth muscle cell line Molecular Pharmacology. 28: 495-501. PMID 2867463  0.161
1978 Scarpace PJ, Parthemore JG, Deftos LJ. The distribution of biologically active and inactive radioiodinated human calcitonin in the rat Endocrinology. 103: 128-132. PMID 744063  0.16
1986 Scarpace PJ, O'Connor SW, Abrass IB. Temperature and isoproterenol modulation of beta-adrenergic receptor characteristics Life Sciences. 38: 309-315. PMID 3003476 DOI: 10.1016/0024-3205(86)90077-9  0.157
1991 Scarpace PJ, Matheny M. Adenylate cyclase agonist properties of CGP-12177A in brown fat: Evidence for atypical β-adrenergic receptors American Journal of Physiology - Endocrinology and Metabolism. 260. PMID 1671733  0.139
1991 Borst SE, Scarpace PJ. Agonist-induced desensitization of liver (α1)-receptors; implications for assessment of PI hydrolysis Second Messengers and Phosphoproteins. 13: 131-139. PMID 1659634  0.138
2001 Hatakeyama Y, Scarpace PJ. Transcriptional regulation of uncoupling protein-2 gene expression in L6 myotubes International Journal of Obesity. 25: 1619-1624. PMID 11753581 DOI: 10.1038/sj.ijo.0801812  0.128
1987 Scarpace PJ, Armbrecht HJ. Adenylate cyclase in senescence: Catecholamine and parathyroid hormone pathways Journal of Basic and Clinical Physiology and Pharmacology. 6: 105-118. DOI: 10.1515/JBCPP.1987.6.2.105  0.126
1988 Rosenthal MJ, Morley JE, Flood JF, Scarpace PJ. Relationship between behavioral and motor responses of mature and old mice and cerebellar beta-adrenergic receptor density Mechanisms of Ageing and Development. 45: 231-237. PMID 2853259 DOI: 10.1016/0047-6374(88)90005-X  0.123
1989 Scarpace PJ, Bender BS. Viral pneumonia attenuates adenylate cyclase but not beta-adrenergic receptors in murine lung American Review of Respiratory Disease. 140: 1602-1606. PMID 2557784  0.121
1982 Scarpace PJ, Littner MR, Tashkin DP, Abrass IB. Lymphocyte beta-adrenergic refractoriness induced by theophylline or metaproterenol in healthy and asthmatic subjects Life Sciences. 31: 1567-1573. PMID 6292641 DOI: 10.1016/0024-3205(82)90048-0  0.104
1985 Scarpace PJ, Abrass IB. Recovery from persistent beta-adrenergic receptor down-regulation Federation Proceedings. 44.  0.095
2006 Tumer N, Matheny M, Scarpace P. Tu-P7:1 Chronic central overexpression of leptin elevates blood pressure despite extreme hypoleptinemia Atherosclerosis Supplements. 7: 185. DOI: 10.1016/S1567-5688(06)80710-5  0.084
1973 Scarpace PJ, Neuman WF. Quantitation of CaP2+ fluxes in chick calvaria Bba - Biomembranes. 323: 267-275. PMID 4796209 DOI: 10.1016/0005-2736(73)90150-8  0.067
1983 Scarpace PJ, O'Connor SW, Abrass IB. The thermal lability of adenylate cyclase: Mechanisms of stabilization Life Sciences. 32: 817-824. PMID 6681857 DOI: 10.1016/0024-3205(83)90217-5  0.065
1976 Scarpace PJ, Neuman WF. The blood: Bone disequilibrium - I. The active accumulation of K+ into the bone extracellular fluid Calcified Tissue Research. 20: 137-149. DOI: 10.1007/BF02546403  0.049
1976 Scarpace PJ, Neuman WF. The blood: bone disequilibrium. I. The active accumulation of K+ into the bone extracellular fluid Calcified Tissue Research. 137-149. PMID 1260484 DOI: 10.1007/Bf02546403  0.046
1976 Scarpace PJ, Neuman WF. The blood: Bone disequilibrium - II. Evidence against the active accumulation of calcium or phosphate into the bone extracellular fluid Calcified Tissue Research. 20: 151-158. DOI: 10.1007/Bf02546404  0.044
1976 Scarpace PJ, Neuman WF. The blood: bone disequilibrium. II. Evidence against the active accumulation of calcium or phosphate into the bone extracellular fluid Calcified Tissue Research. 151-158. PMID 1260485  0.043
1974 Scarpace PJ, Neuman WF. Evidence for a ouabain sensitive noncellular K pool in chick calvaria Federation Proceedings. 33.  0.039
Hide low-probability matches.