Andrea J. Tenner - Related publications

University of California, Irvine, Irvine, CA 
Neuroscience Biology, Immunology
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Webers A, Heneka MT, Gleeson PA. The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease. Immunology and Cell Biology. PMID 31654430 DOI: 10.1111/imcb.12301   
2019 Sho M, Ichiyanagi N, Imaizumi K, Ishikawa M, Morimoto S, Watanabe H, Okano H. A combinational treatment of carotenoids decreases Aβ secretion in human neurons via β-secretase inhibition. Neuroscience Research. PMID 31606373 DOI: 10.1016/j.neures.2019.10.006   
2019 Zhang Z, Shen Q, Wu X, Zhang D, Xing D. Activation of PKA/SIRT1 signaling pathway by photobiomodulation therapy reduces Aβ levels in Alzheimer's disease models. Aging Cell. e13054. PMID 31663252 DOI: 10.1111/acel.13054   
2019 Guzman-Martinez L, Maccioni RB, Andrade V, Navarrete LP, Pastor MG, Ramos-Escobar N. Neuroinflammation as a Common Feature of Neurodegenerative Disorders. Frontiers in Pharmacology. 10: 1008. PMID 31572186 DOI: 10.3389/fphar.2019.01008   
2019 Wu H, Wu ZG, Shi WJ, Gao H, Wu HH, Bian F, Jia PP, Hou YN. Effects of progesterone on glucose uptake in neurons of Alzheimer's disease animals and cell models. Life Sciences. 116979. PMID 31647947 DOI: 10.1016/j.lfs.2019.116979   
2019 Park J, Baik SH, Mook-Jung I, Irimia D, Cho H. Mimicry of Central-Peripheral Immunity in Alzheimer's Disease and Discovery of Neurodegenerative Roles in Neutrophil. Frontiers in Immunology. 10: 2231. PMID 31611872 DOI: 10.3389/fimmu.2019.02231   
2019 Pradeepkiran JA, Reddy AP, Yin X, Manczak M, Reddy PH. Protective Effects of BACE1 Inhibitory Ligand Molecules Against Amyloid Beta-Induced Synaptic and Mitochondrial Toxicities in Alzheimer's Disease. Human Molecular Genetics. PMID 31595293 DOI: 10.1093/hmg/ddz227   
2019 Faridi A, Yang W, Kelly HG, Wang C, Faridi P, Purcell AW, Davis TP, Chen P, Kent SJ, Ke PC. Differential roles of plasma protein corona on immune cell association and cytokine secretion of oligomeric and fibrillar beta-amyloid. Biomacromolecules. PMID 31600059 DOI: 10.1021/acs.biomac.9b01116   
2019 Grimaldi A, Pediconi N, Oieni F, Pizzarelli R, Rosito M, Giubettini M, Santini T, Limatola C, Ruocco G, Ragozzino D, Di Angelantonio S. Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer's Disease Patients, Possible Biomarkers for Early Diagnosis. Frontiers in Neuroscience. 13: 925. PMID 31551688 DOI: 10.3389/fnins.2019.00925   
2019 García-González L, Pilat D, Baranger K, Rivera S. Emerging Alternative Proteinases in APP Metabolism and Alzheimer's Disease Pathogenesis: A Focus on MT1-MMP and MT5-MMP. Frontiers in Aging Neuroscience. 11: 244. PMID 31607898 DOI: 10.3389/fnagi.2019.00244   
2019 Mputhia Z, Hone E, Tripathi T, Sargeant T, Martins R, Bharadwaj P. Autophagy Modulation as a Treatment of Amyloid Diseases. Molecules (Basel, Switzerland). 24. PMID 31527516 DOI: 10.3390/molecules24183372   
2019 Naushad M, Durairajan SSK, Bera AK, Senapati S, Li M. Natural Compounds with Anti-BACE1 Activity as Promising Therapeutic Drugs for Treating Alzheimer's Disease. Planta Medica. PMID 31618777 DOI: 10.1055/a-1019-9819   
2019 Xie Y, Niu M, Ji C, Huang TY, Zhang C, Tian Y, Shi Z, Wang C, Zhao Y, Luo H, Can D, Xu H, Zhang YW, Zhang X. SNX8 Enhances Non-amyloidogenic APP Trafficking and Attenuates Aβ Accumulation and Memory Deficits in an AD Mouse. Frontiers in Cellular Neuroscience. 13: 410. PMID 31551717 DOI: 10.3389/fncel.2019.00410   
2019 Velazquez R, Ferreira E, Knowles S, Fux C, Rodin A, Winslow W, Oddo S. Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation. Aging Cell. e13037. PMID 31560162 DOI: 10.1111/acel.13037   
2019 Caleb AA, Akiyama T, Kimura A, Kimura Y, Takahashi-Jitsuki A, Nakamura H, Makihara H, Masukawa D, Nakabayashi J, Hirano H, Nakamura F, Saito T, Saido T, Goshima Y. Network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with Aβ in a mice model of early-stage Alzheimer's disease. Neurobiology of Disease. 104603. PMID 31494281 DOI: 10.1016/j.nbd.2019.104603   
2019 Folch J, Olloquequi J, Ettcheto M, Busquets O, Sánchez-López E, Cano A, Espinosa-Jiménez T, García ML, Beas-Zarate C, Casadesús G, Bulló M, Auladell C, Camins A. The Involvement of Peripheral and Brain Insulin Resistance in Late Onset Alzheimer's Dementia. Frontiers in Aging Neuroscience. 11: 236. PMID 31551756 DOI: 10.3389/fnagi.2019.00236   
2019 Zheng Y, Deng Y, Gao JM, Lv C, Lang LH, Shi JS, Yu CY, Gong QH. Icariside II inhibits lipopolysaccharide-induced inflammation and amyloid production in rat astrocytes by regulating IKK/IκB/NF-κB/BACE1 signaling pathway. Acta Pharmacologica Sinica. PMID 31554962 DOI: 10.1038/s41401-019-0300-2   
2019 Aikawa T, Ren Y, Yamazaki Y, Tachibana M, Johnson MR, Anderson CT, Martens YA, Holm ML, Asmann YW, Saito T, Saido TC, Fitzgerald ML, Bu G, Kanekiyo T. ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31690660 DOI: 10.1073/pnas.1908529116   
2019 Mancuso R, Van Den Daele J, Fattorelli N, Wolfs L, Balusu S, Burton O, Liston A, Sierksma A, Fourne Y, Poovathingal S, Arranz-Mendiguren A, Sala Frigerio C, Claes C, Serneels L, Theys T, et al. Stem-cell-derived human microglia transplanted in mouse brain to study human disease. Nature Neuroscience. PMID 31659342 DOI: 10.1038/s41593-019-0525-x   
2019 Shi Y, Manis M, Long J, Wang K, Sullivan PM, Remolina Serrano J, Hoyle R, Holtzman DM. Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model. The Journal of Experimental Medicine. PMID 31601677 DOI: 10.1084/jem.20190980   
2019 Guo E, Hu Y, Du T, Zhu H, Chen L, Qu W, Zhang J, Xie N, Liu W, Feng F, Xu J. Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo. Bioorganic Chemistry. 92: 103258. PMID 31520892 DOI: 10.1016/j.bioorg.2019.103258   
2019 Cai T, Morishima K, Takagi-Niidome S, Tominaga A, Tomita T. Conformational dynamics of transmembrane domain 3 of presenilin 1 is associated with the trimming activity of γ-secretase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31527118 DOI: 10.1523/JNEUROSCI.0838-19.2019   
2019 Yamazaki Y, Shinohara M, Yamazaki A, Ren Y, Asmann YW, Kanekiyo T, Bu G. ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313169. PMID 31665905 DOI: 10.1161/ATVBAHA.119.313169   
2019 Wang H, Shen Y, Chuang H, Chiu C, Ye Y, Zhao L. Neuroinflammation in Alzheimer's Disease: Microglia, Molecular Participants and Therapeutic Choices. Current Alzheimer Research. 16: 659-674. PMID 31580243 DOI: 10.2174/1567205016666190503151648   
2019 Pendin D, Fasolato C, Basso E, Filadi R, Greotti E, Galla L, Gomiero C, Leparulo A, Redolfi N, Scremin E, Vajente N, Pozzan T, Pizzo P. Familial Alzheimer's disease presenilin-2 mutants affect Ca homeostasis and brain network excitability. Aging Clinical and Experimental Research. PMID 31606858 DOI: 10.1007/s40520-019-01341-0   
2019 Sushma, Mondal AC. Role of GPCR signaling and calcium dysregulation in Alzheimer's disease. Molecular and Cellular Neurosciences. 103414. PMID 31655116 DOI: 10.1016/j.mcn.2019.103414   
2019 Ahmad SS, Khan S, Kamal MA, Wasi U. The structure and function of α, β and γ-Secretase as therapeutic target enzymes into the development of Alzheimer's disease: A review. Cns & Neurological Disorders Drug Targets. PMID 31608840 DOI: 10.2174/1871527318666191011145941   
2019 Vander Zanden CM, Chi EY. Passive immunotherapies targeting amyloid beta and tau oligomers in Alzheimer's disease. Journal of Pharmaceutical Sciences. PMID 31647950 DOI: 10.1016/j.xphs.2019.10.024   
2019 Doens D, Valdés-Tresanco ME, Vasquez V, Carreira MB, De La Guardia Y, Stephens DE, Nguyen VD, Nguyen VT, Gu J, Hegde M, Larionov OV, Valiente PA, Lleonart R, L Fernandez P. Hexahydropyrrolo[2,3-b]indole compounds as potential therapeutics for Alzheimer Disease. Acs Chemical Neuroscience. PMID 31545596 DOI: 10.1021/acschemneuro.9b00297   
2019 Park MH, Lee M, Nam G, Kim M, Kang J, Choi BJ, Jeong MS, Park KH, Han WH, Tak E, Kim MS, Lee J, Lin Y, Lee YH, Song IS, et al. ,'-Diacetyl--phenylenediamine restores microglial phagocytosis and improves cognitive defects in Alzheimer's disease transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 31685616 DOI: 10.1073/pnas.1916318116   
2019 Liang ZM, Peng YH, Chen Y, Long LL, Luo HJ, Chen YJ, Liang YL, Tian YH, Li SJ, Shi YS, Zhang XM. The BACE1-Specific DNA Aptamer A1 Rescues Amyloid-β Pathology and Behavioral Deficits in a Mouse Model of Alzheimer's Disease. Nucleic Acid Therapeutics. PMID 31513457 DOI: 10.1089/nat.2019.0812   
2019 Han J, Ji Y, Youn K, Lim G, Lee J, Kim DH, Jun M. Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches. Nutrients. 11. PMID 31703329 DOI: 10.3390/nu11112694   
2019 Huynh TV, Wang C, Tran AC, Tabor GT, Mahan TE, Francis CM, Finn MB, Spellman R, Manis M, Tanzi RE, Ulrich JD, Holtzman DM. Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model. Molecular Neurodegeneration. 14: 37. PMID 31623648 DOI: 10.1186/s13024-019-0337-1   
2019 Li TR, Wang XN, Sheng C, Li YX, Li FZ, Sun Y, Han Y. Extracellular vesicles as an emerging tool for the early detection of Alzheimer's disease. Mechanisms of Ageing and Development. 111175. PMID 31678325 DOI: 10.1016/j.mad.2019.111175   
2019 Hemonnot AL, Hua J, Ulmann L, Hirbec H. Microglia in Alzheimer Disease: Well-Known Targets and New Opportunities. Frontiers in Aging Neuroscience. 11: 233. PMID 31543810 DOI: 10.3389/fnagi.2019.00233   
2019 Hemonnot AL, Hua J, Ulmann L, Hirbec H. Microglia in Alzheimer Disease: Well-Known Targets and New Opportunities. Frontiers in Aging Neuroscience. 11: 233. PMID 31543810 DOI: 10.3389/fnagi.2019.00233   
2019 Verkhratsky A, Parpura V, Rodriguez-Arellano JJ, Zorec R. Astroglia in Alzheimer's Disease. Advances in Experimental Medicine and Biology. 1175: 273-324. PMID 31583592 DOI: 10.1007/978-981-13-9913-8_11   
2019 Oksanen M, Hyötyläinen I, Trontti K, Rolova T, Wojciechowski S, Koskuvi M, Viitanen M, Levonen AL, Hovatta I, Roybon L, Lehtonen Š, Kanninen KM, Hämäläinen RH, Koistinaho J. NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes. Glia. PMID 31670864 DOI: 10.1002/glia.23741   
2019 Liu K, Ma C, Su J, Sun Y, Shen N, Li B, Feng Y, Yang X, Wu H, Zhang H, Herrmann A, Tanzi R, Zhang C. Significant upregulation of Alzheimer's β-amyloid levels in living system induced by extracellular elastin polypeptides. Angewandte Chemie (International Ed. in English). PMID 31609093 DOI: 10.1002/anie.201912399   
2019 Cheng CH, Lin KJ, Hong CT, Wu D, Chang HM, Liu CH, Hsiao IT, Yang CP, Liu YC, Hu CJ. Plasmon-Activated Water Reduces Amyloid Burden and Improves Memory in Animals with Alzheimer's Disease. Scientific Reports. 9: 13252. PMID 31520077 DOI: 10.1038/s41598-019-49731-8   
2019 Takayama KI, Fujiwara K, Inoue S. APP, an androgen-regulated gene, is targeted by RNA-binding protein PSF/SFPQ in neuronal cells. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 31541592 DOI: 10.1111/gtc.12721   
2019 Liu J, Li L. Targeting Autophagy for the Treatment of Alzheimer's Disease: Challenges and Opportunities. Frontiers in Molecular Neuroscience. 12: 203. PMID 31507373 DOI: 10.3389/fnmol.2019.00203   
2019 Wan Y, Liang Y, Liang F, Shen N, Shinozuka K, Yu JT, Ran C, Quan Q, Tanzi RE, Zhang C. A Curcumin Analog Reduces Levels of the Alzheimer's Disease-Associated Amyloid-β Protein by Modulating AβPP Processing and Autophagy. Journal of Alzheimer's Disease : Jad. PMID 31640096 DOI: 10.3233/JAD-190562   
2019 Zhang H, Zheng Y. [β Amyloid Hypothesis in Alzheimer's Disease:Pathogenesis,Prevention,and Management]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 41: 702-708. PMID 31699204 DOI: 10.3881/j.issn.1000-503X.10875   
2019 Liu T, Woo JA, Yan Y, LePochat P, Bukhari MZ, Kang DE. Dual role of cofilin in APP trafficking and amyloid-β clearance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201901268R. PMID 31646885 DOI: 10.1096/fj.201901268R   
2019 Rose KN, Barlock BJ, DaSilva NA, Johnson SL, Liu C, Ma H, Nelson R, Akhlaghi F, Seeram NP. Anti-neuroinflammatory effects of a food-grade phenolic-enriched maple syrup extract in a mouse model of Alzheimer's disease. Nutritional Neuroscience. 1-10. PMID 31583972 DOI: 10.1080/1028415X.2019.1672009   
2019 Huang P, Zheng N, Zhou HB, Huang J. Curcumin inhibits BACE1 expression through the interaction between ERβ and NFκB signaling pathway in SH-SY5Y cells. Molecular and Cellular Biochemistry. PMID 31595422 DOI: 10.1007/s11010-019-03638-0   
2019 Iqbal K, Liu F, Gong C, Dai C, Hu W. Why delay in effective treatment for Alzheimer's disease and related conditions. Progress in Molecular Biology and Translational Science. 168: 243-256. PMID 31699318 DOI: 10.1016/bs.pmbts.2019.08.002   
2019 Zhou R, Yang G, Shi Y. Macromolecular complex in recognition and proteolysis of amyloid precursor protein in Alzheimer's disease. Current Opinion in Structural Biology. 61: 1-8. PMID 31629221 DOI: 10.1016/   
2019 Wang Q, Jiang H, Wang L, Yi H, Li Z, Liu R. Vitegnoside Mitigates Neuronal Injury, Mitochondrial Apoptosis, and Inflammation in an Alzheimer's Disease Cell Model via the p38 MAPK/JNK Pathway. Journal of Alzheimer's Disease : Jad. PMID 31561371 DOI: 10.3233/JAD-190640