Elissa J. Chesler - Publications

Oak Ridge National Laboratory, Oak Ridge, TN, United States 
neurogenetics, alcoholism, gene expression, statistical genetics, behavior genetics

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bubier JA, He H, Philip VM, Roy T, Hernandez CM, Bernat R, Donohue KD, O'Hara BF, Chesler EJ. Genetic variation regulates opioid-induced respiratory depression in mice. Scientific Reports. 10: 14970. PMID 32917924 DOI: 10.1038/s41598-020-71804-2  0.6
2020 Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, ... ... Chesler EJ, et al. Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia. Cell Reports. 32: 108091. PMID 32877673 DOI: 10.1016/j.celrep.2020.108091  0.6
2020 Reynolds T, Johnson E, Huggett S, Bubier JA, Palmer RHC, Agrawal A, Baker EJ, Chesler EJ. Interpretation of psychiatric genome-wide association studies with multispecies heterogeneous functional genomic data integration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32791514 DOI: 10.1038/s41386-020-00795-5  0.6
2020 Bubier JA, Philip VM, Dickson PE, Mittleman G, Chesler EJ. Discovery of a Role for in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis. Frontiers in Neuroscience. 14: 721. PMID 32742255 DOI: 10.3389/fnins.2020.00721  0.6
2020 Tuttle AH, Philip VM, Chesler EJ, Mogil JS. Author Correction: Comparing phenotypic variation between inbred and outbred mice. Nature Methods. PMID 32728193 DOI: 10.1038/s41592-020-0932-7  0.68
2020 Huggett SB, Bubier JA, Chesler EJ, Palmer RHC. Do gene expression findings from mouse models of cocaine use recapitulate human cocaine use disorder in reward circuitry? Genes, Brain, and Behavior. e12689. PMID 32720468 DOI: 10.1111/gbb.12689  0.6
2020 Yang JH, Presby RE, Cayer S, Rotolo RA, Perrino PA, Fitch RH, Correa M, Chesler EJ, Salamone JD. Effort-related decision making in humanized COMT mice: Effects of ValMet polymorphisms and possible implications for negative symptoms in humans. Pharmacology, Biochemistry, and Behavior. 196: 172975. PMID 32593787 DOI: 10.1016/j.pbb.2020.172975  1
2020 Datta U, Schoenrock SE, Bubier JA, Bogue MA, Jentsch JD, Logan RW, Tarantino LM, Chesler EJ. Prospects for finding the mechanisms of sex differences in addiction with human and model organism genetic analysis. Genes, Brain, and Behavior. PMID 32012419 DOI: 10.1111/gbb.12645  0.6
2020 Schoenrock SA, Kumar P, Gómez-A A, Dickson PE, Kim SM, Bailey L, Neira S, Riker KD, Farrington J, Gaines CH, Khan S, Wilcox TD, Roy TA, Leonardo MR, Olson AA, ... ... Chesler EJ, et al. Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine. Psychopharmacology. PMID 31897574 DOI: 10.1007/s00213-019-05429-3  0.52
2020 Bubier JA, Philip VM, Quince C, Campbell J, Zhou Y, Vishnivetskaya T, Duvvuru S, Hageman Blair R, Ndukum J, Donohue KD, Foster CM, Mellert DJ, Weinstock G, Culiat CT, O'Hara B, ... ... Chesler EJ, et al. A Microbe Associated with Sleep Revealed by a Novel Systems-Genetic Analysis of the Microbiome in Collaborative Cross Mice. Genetics. PMID 31896565 DOI: 10.1534/genetics.119.303013  0.6
2019 Bogue MA, Philip VM, Walton DO, Grubb SC, Dunn MH, Kolishovski G, Emerson J, Mukherjee G, Stearns T, He H, Sinha V, Kadakkuzha B, Kunde-Ramamoorthy G, Chesler EJ. Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data. Nucleic Acids Research. PMID 31696236 DOI: 10.1093/nar/gkz1032  0.52
2019 Phillips CA, Wang K, Baker EJ, Bubier JA, Chesler EJ, Langston MA. On Finding and Enumerating Maximal and Maximum -Partite Cliques in -Partite Graphs. Algorithms. 12. PMID 31448059 DOI: 10.3390/a12010023  0.6
2019 Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ. Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response. Pain. 160: 1740-1753. PMID 31335644 DOI: 10.1097/j.pain.0000000000001571  0.6
2019 Saul MC, Philip VM, Reinholdt LG, Chesler EJ. High-Diversity Mouse Populations for Complex Traits. Trends in Genetics : Tig. PMID 31133439 DOI: 10.1016/j.tig.2019.04.003  0.52
2019 Boehm FJ, Chesler EJ, Yandell BS, Broman KW. Testing Pleiotropy Separate QTL in Multiparental Populations. G3 (Bethesda, Md.). PMID 31092608 DOI: 10.1534/g3.119.400098  0.72
2019 Bubier JA, Sutphin GL, Reynolds TJ, Korstanje R, Fuksman-Kumpa A, Baker EJ, Langston MA, Chesler EJ. Integration of heterogeneous functional genomics data in gerontology research to find genes and pathway underlying aging across species. Plos One. 14: e0214523. PMID 30978202 DOI: 10.1371/journal.pone.0214523  0.6
2019 Recla JM, Bubier JA, Gatti DM, Ryan JL, Long KH, Robledo RF, Glidden NC, Hou G, Churchill GA, Maser RS, Zhang ZW, Young EE, Chesler EJ, Bult CJ. Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response. Pain. PMID 30925521 DOI: 10.1097/j.pain.0000000000001571  0.6
2019 Goodwin LO, Splinter E, Davis TL, Urban R, He H, Braun RE, Chesler EJ, Kumar V, van Min M, Ndukum J, Philip VM, Reinholdt LG, Svenson K, White JK, Sasner M, et al. Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis. Genome Research. PMID 30659012 DOI: 10.1101/gr.233866.117  0.52
2018 Tuttle AH, Philip VM, Chesler EJ, Mogil JS. Author Correction: Comparing phenotypic variation between inbred and outbred mice. Nature Methods. PMID 30584248 DOI: 10.1038/s41592-018-0298-2  0.68
2018 Tuttle AH, Philip VM, Chesler EJ, Mogil JS. Comparing phenotypic variation between inbred and outbred mice. Nature Methods. 15: 994-996. PMID 30504873 DOI: 10.1038/s41592-018-0224-7  0.68
2018 Yuan JT, Gatti DM, Philip VM, Kasparek S, Kreuzman AM, Mansky B, Sharif K, Taterra D, Taylor WM, Thomas M, Ward JO, Holmes A, Chesler EJ, Parker CC. Genome-wide association for testis weight in the diversity outbred mouse population. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 29691636 DOI: 10.1007/s00335-018-9745-8  0.52
2018 Kafkafi N, Agassi J, Chesler EJ, Crabbe JC, Crusio WE, Eilam D, Gerlai R, Golani I, Gomez-Marin A, Heller R, Iraqi F, Jaljuli I, Karp NA, Morgan H, Nicholson G, et al. Reproducibility and replicability of rodent phenotyping in preclinical studies. Neuroscience and Biobehavioral Reviews. PMID 29357292 DOI: 10.1016/j.neubiorev.2018.01.003  0.96
2017 Bogue MA, Grubb SC, Walton DO, Philip VM, Kolishovski G, Stearns T, Dunn MH, Skelly DA, Kadakkuzha B, TeHennepe G, Kunde-Ramamoorthy G, Chesler EJ. Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice. Nucleic Acids Research. PMID 29136208 DOI: 10.1093/nar/gkx1082  0.52
2017 Delprato A, Algéo MP, Bonheur B, Bubier JA, Lu L, Williams RW, Chesler EJ, Crusio WE. QTL and Systems Genetics Analysis of Mouse Grooming and Behavioral Responses to Novelty in an Open Field. Genes, Brain, and Behavior. PMID 28544613 DOI: 10.1111/gbb.12392  0.96
2017 Parker CC, Dickson PE, Philip VM, Thomas M, Chesler EJ. Systems Genetic Analysis in GeneNetwork.org. Current Protocols in Neuroscience. 79: 8.39.1-8.39.20. PMID 28398643 DOI: 10.1002/cpns.23  0.52
2017 Bubier JA, Langston MA, Baker EJ, Chesler EJ. Integrative Functional Genomics for Systems Genetics in GeneWeaver.org. Methods in Molecular Biology (Clifton, N.J.). 1488: 131-152. PMID 27933523 DOI: 10.1007/978-1-4939-6427-7_6  0.6
2016 Crusio WE, Dhawan E, Chesler EJ, Delprato A. Analysis of morphine responses in mice reveals a QTL on Chromosome 7. F1000research. 5: 2156. PMID 27746909 DOI: 10.12688/f1000research.9484.1  0.6
2016 Young EE, Bryant CD, Lee SE, Peng X, Cook B, Nair HK, Dreher KJ, Zhang X, Palmer AA, Chung JM, Mogil JS, Chesler EJ, Lariviere WR. Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test. Genes, Brain, and Behavior. PMID 27231153 DOI: 10.1111/gbb.12302  1
2016 Putman AH, Wolen AR, Harenza J, Yordanova RK, Webb BT, Chesler EJ, Miles MF. Identification of Quantitative Trait Loci and Candidate Genes for an Anxiolytic-like Response to Ethanol in BXD Recombinant Inbred Strains. Genes, Brain, and Behavior. PMID 26948279 DOI: 10.1111/gbb.12289  1
2016 Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, et al. R2d2 drives selfish sweeps in the house mouse. Molecular Biology and Evolution. PMID 26882987 DOI: 10.1093/molbev/msw036  1
2016 Bubier JA, Wilcox TD, Jay JJ, Langston MA, Baker EJ, Chesler EJ. Cross-Species Integrative Functional Genomics in GeneWeaver Reveals a Role for Pafah1b1 in Altered Response to Alcohol. Frontiers in Behavioral Neuroscience. 10: 1. PMID 26834590 DOI: 10.3389/fnbeh.2016.00001  1
2015 Baker E, Bubier JA, Reynolds T, Langston MA, Chesler EJ. GeneWeaver: data driven alignment of cross-species genomics in biology and disease. Nucleic Acids Research. PMID 26656951 DOI: 10.1093/nar/gkv1329  0.6
2015 Dickson PE, Miller MM, Calton MA, Bubier JA, Cook MN, Goldowitz D, Chesler EJ, Mittleman G. Systems genetics of intravenous cocaine self-administration in the BXD recombinant inbred mouse panel. Psychopharmacology. PMID 26581503 DOI: 10.1007/s00213-015-4147-z  1
2015 Rutledge H, Baran-Gale J, de Villena FP, Chesler EJ, Churchill GA, Sethupathy P, Kelada SN. Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population. Bmc Genomics. 16: 633. PMID 26303911 DOI: 10.1186/s12864-015-1732-9  1
2015 Dickson PE, McNaughton KA, Hou L, Anderson LC, Long KH, Chesler EJ. Sex and strain influence attribution of incentive salience to reward cues in mice. Behavioural Brain Research. PMID 26102561 DOI: 10.1016/j.bbr.2015.05.039  1
2015 Bubier JA, Phillips CA, Langston MA, Baker EJ, Chesler EJ. GeneWeaver: finding consilience in heterogeneous cross-species functional genomics data. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 26092690 DOI: 10.1007/s00335-015-9575-x  1
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/journal.pgen.1004850  1
2015 Padula AE, Griffin WC, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ. KCNN Genes that Encode Small-Conductance Ca(2+)-Activated K(+) Channels Influence Alcohol and Drug Addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1928-39. PMID 25662840 DOI: 10.1038/npp.2015.42  0.96
2015 Ha T, Swanson D, Larouche M, Glenn R, Weeden D, Zhang P, Hamre K, Langston M, Phillips C, Song M, Ouyang Z, Chesler E, Duvvurru S, Yordanova R, Cui Y, et al. CbGRiTS: cerebellar gene regulation in time and space. Developmental Biology. 397: 18-30. PMID 25446528 DOI: 10.1016/j.ydbio.2014.09.032  1
2015 Dickson PE, Ndukum J, Wilcox T, Clark J, Roy B, Zhang L, Li Y, Lin DT, Chesler EJ. Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice. Psychopharmacology. 232: 1011-24. PMID 25238945 DOI: 10.1007/s00213-014-3737-5  1
2015 Bogue MA, Churchill GA, Chesler EJ. Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database Mammalian Genome. DOI: 10.1007/s00335-015-9595-6  1
2014 Bogue MA, Peters LL, Paigen B, Korstanje R, Yuan R, Ackert-Bicknell C, Grubb SC, Churchill GA, Chesler EJ. Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25533306 DOI: 10.1093/gerona/glu223  1
2014 Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA. Quantitative trait locus mapping methods for diversity outbred mice. G3 (Bethesda, Md.). 4: 1623-33. PMID 25237114 DOI: 10.1534/g3.114.013748  1
2014 Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP, Kelada SN. Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in murine lung. Genetics. 198: 735-45. PMID 25114278 DOI: 10.1534/genetics.114.168138  1
2014 Bubier JA, Jay JJ, Baker CL, Bergeson SE, Ohno H, Metten P, Crabbe JC, Chesler EJ. Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics. Genetics. 197: 1377-93. PMID 24923803 DOI: 10.1534/genetics.114.166165  1
2014 Zhang Y, Phillips CA, Rogers GL, Baker EJ, Chesler EJ, Langston MA. On finding bicliques in bipartite graphs: a novel algorithm and its application to the integration of diverse biological data types. Bmc Bioinformatics. 15: 110. PMID 24731198 DOI: 10.1186/1471-2105-15-110  1
2014 Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ. Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 211-22. PMID 24700285 DOI: 10.1007/s00335-014-9508-0  1
2014 Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS. Integrative genetic analysis of allergic inflammation in the murine lung. American Journal of Respiratory Cell and Molecular Biology. 51: 436-45. PMID 24693920 DOI: 10.1165/rcmb.2013-0501OC  1
2014 Liu EY, Morgan AP, Chesler EJ, Wang W, Churchill GA, Pardo-Manuel de Villena F. High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline. Genetics. 197: 91-106. PMID 24578350 DOI: 10.1534/genetics.114.161653  1
2014 Chesler EJ. Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 25: 3-11. PMID 24272351 DOI: 10.1007/s00335-013-9492-9  1
2014 Jay JJ, Chesler EJ. Performing integrative functional genomics analysis in GeneWeaver.org. Methods in Molecular Biology (Clifton, N.J.). 1101: 13-29. PMID 24233775 DOI: 10.1007/978-1-62703-721-1_2  1
2014 Chesler EJ, Baker EJ. Contributions of Genomic and Informatic Approaches to Understanding Alcohol Dependence: From Genes to Networks Neurobiology of Alcohol Dependence. 523-537. DOI: 10.1016/B978-0-12-405941-2.00025-0  1
2013 Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, Churchill GA, Chesler EJ. High-precision genetic mapping of behavioral traits in the diversity outbred mouse population. Genes, Brain, and Behavior. 12: 424-37. PMID 23433259 DOI: 10.1111/gbb.12029  1
2013 DuBose CS, Chesler EJ, Goldowitz D, Hamre KM. Use of the expanded panel of BXD mice narrow QTL regions in ethanol-induced locomotor activation and motor incoordination. Alcoholism, Clinical and Experimental Research. 37: 170-83. PMID 23289978 DOI: 10.1111/j.1530-0277.2012.01865.x  1
2013 Jay JJ, Baker EJ, Chesler EJ. A context-driven gene prioritization method for web-based functional genomics Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7875: 161-172. DOI: 10.1007/978-3-642-38036-5_18  1
2012 Chesler EJ, Logan RW. Opportunities for bioinformatics in the classification of behavior and psychiatric disorders. International Review of Neurobiology. 104: 183-211. PMID 23195316 DOI: 10.1016/B978-0-12-398323-7.00008-2  1
2012 Chesler EJ, Haendel MA. The field of bioinformatics. Preface. International Review of Neurobiology. 103: xi-xii. PMID 23195125 DOI: 10.1016/B978-0-12-388408-4.09986-X  1
2012 Haendel MA, Chesler EJ. Lost and found in behavioral informatics. International Review of Neurobiology. 103: 1-18. PMID 23195118 DOI: 10.1016/B978-0-12-388408-4.00001-0  1
2012 Parsons MJ, Grimm C, Paya-Cano JL, Fernandes C, Liu L, Philip VM, Chesler EJ, Nietfeld W, Lehrach H, Schalkwyk LC. Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains. Bmc Genomics. 13: 476. PMID 22974136 DOI: 10.1186/1471-2164-13-476  1
2012 Thaisz J, Tsaih SW, Feng M, Philip VM, Zhang Y, Yanas L, Sheehan S, Xu L, Miller DR, Paigen B, Chesler EJ, Churchill GA, Dipetrillo K. Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populations. American Journal of Physiology. Renal Physiology. 303: F972-81. PMID 22859403 DOI: 10.1152/ajprenal.00690.2011  1
2012 Ha TJ, Swanson DJ, Kirova R, Yeung J, Choi K, Tong Y, Chesler EJ, Goldowitz D. Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum. The European Journal of Neuroscience. 36: 2888-98. PMID 22817342 DOI: 10.1111/j.1460-9568.2012.08221.x  1
2012 Jay JJ, Eblen JD, Zhang Y, Benson M, Perkins AD, Saxton AM, Voy BH, Chesler EJ, Langston MA. A systematic comparison of genome-scale clustering algorithms. Bmc Bioinformatics. 13: S7. PMID 22759431 DOI: 10.1186/1471-2105-13-S10-S7  1
2012 Campbell JH, Foster CM, Vishnivetskaya T, Campbell AG, Yang ZK, Wymore A, Palumbo AV, Chesler EJ, Podar M. Host genetic and environmental effects on mouse intestinal microbiota. The Isme Journal. 6: 2033-44. PMID 22695862 DOI: 10.1038/ismej.2012.54  1
2012 Bubier JA, Chesler EJ. Accelerating discovery for complex neurological and behavioral disorders through systems genetics and integrative genomics in the laboratory mouse. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 9: 338-48. PMID 22422471 DOI: 10.1007/s13311-012-0111-3  1
2012 Chesler EJ, Plitt A, Fisher D, Hurd B, Lederle L, Bubier JA, Kiselycznyk C, Holmes A. Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J×129S1/SvImJ inbred mouse cross. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 305-21. PMID 22371272 DOI: 10.1007/s00335-012-9394-2  1
2012 Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA. High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics. 190: 437-47. PMID 22345611 DOI: 10.1534/genetics.111.132597  1
2012 Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, ... ... Chesler EJ, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/genetics.111.132639  1
2012 Baker EJ, Jay JJ, Bubier JA, Langston MA, Chesler EJ. GeneWeaver: a web-based system for integrative functional genomics. Nucleic Acids Research. 40: D1067-76. PMID 22080549 DOI: 10.1093/nar/gkr968  1
2011 Gelinas R, Chesler EJ, Vasconcelos D, Miller DR, Yuan Y, Wang K, Galas D. A genetic approach to the prediction of drug side effects: bleomycin induces concordant phenotypes in mice of the collaborative cross. Pharmacogenomics and Personalized Medicine. 4: 35-45. PMID 23226052 DOI: 10.2147/PGPM.S22475  1
2011 Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Shaw GS, Shinpock S, ... ... Chesler EJ, et al. Genetic analysis in the Collaborative Cross breeding population. Genome Research. 21: 1223-38. PMID 21734011 DOI: 10.1101/gr.113886.110  1
2011 Mathes WF, Aylor DL, Miller DR, Churchill GA, Chesler EJ, de Villena FP, Threadgill DW, Pomp D. Architecture of energy balance traits in emerging lines of the Collaborative Cross. American Journal of Physiology. Endocrinology and Metabolism. 300: E1124-34. PMID 21427413 DOI: 10.1152/ajpendo.00707.2010  1
2011 Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, ... ... Chesler EJ, et al. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Research. 21: 1213-22. PMID 21406540 DOI: 10.1101/gr.111310.110  1
2011 Meehan TF, Carr CJ, Jay JJ, Bult CJ, Chesler EJ, Blake JA. Autism candidate genes via mouse phenomics. Journal of Biomedical Informatics. 44: S5-11. PMID 21397722 DOI: 10.1016/j.jbi.2011.03.003  1
2011 Dickson PE, Rogers TD, Lester DB, Miller MM, Matta SG, Chesler EJ, Goldowitz D, Blaha CD, Mittleman G. Genotype-dependent effects of adolescent nicotine exposure on dopamine functional dynamics in the nucleus accumbens shell in male and female mice: a potential mechanism underlying the gateway effect of nicotine. Psychopharmacology. 215: 631-42. PMID 21212937 DOI: 10.1007/s00213-010-2159-2  1
2011 Nair HK, Hain H, Quock RM, Philip VM, Chesler EJ, Belknap JK, Lariviere WR. Genomic loci and candidate genes underlying inflammatory nociception. Pain. 152: 599-606. PMID 21195549 DOI: 10.1016/j.pain.2010.11.029  1
2011 Jay JJ, Eblen JD, Zhang Y, Benson M, Perkins AD, Saxton AM, Voy BH, Chesler EJ, Langston MA. A systematic comparison of genome scale clustering algorithms (extended abstract) Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6674: 416-427. DOI: 10.1007/978-3-642-21260-4_39  1
2010 Gatti DM, Zhao N, Chesler EJ, Bradford BU, Shabalin AA, Yordanova R, Lu L, Rusyn I. Sex-specific gene expression in the BXD mouse liver. Physiological Genomics. 42: 456-68. PMID 20551147 DOI: 10.1152/physiolgenomics.00110.2009  1
2010 Chesler EJ, Baker EJ. The importance of open-source integrative genomics to drug discovery. Current Opinion in Drug Discovery & Development. 13: 310-6. PMID 20443164  1
2010 Lynch RM, Naswa S, Rogers GL, Kania SA, Das S, Chesler EJ, Saxton AM, Langston MA, Voy BH. Identifying genetic loci and spleen gene coexpression networks underlying immunophenotypes in BXD recombinant inbred mice. Physiological Genomics. 41: 244-53. PMID 20179155 DOI: 10.1152/physiolgenomics.00020.2010  1
2010 Spindler KR, Welton AR, Lim ES, Duvvuru S, Althaus IW, Imperiale JE, Daoud AI, Chesler EJ. The major locus for mouse adenovirus susceptibility maps to genes of the hematopoietic cell surface-expressed LY6 family. Journal of Immunology (Baltimore, Md. : 1950). 184: 3055-62. PMID 20164425 DOI: 10.4049/jimmunol.0903363  1
2010 Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ. High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes, Brain, and Behavior. 9: 129-59. PMID 19958391 DOI: 10.1111/j.1601-183X.2009.00540.x  1
2009 Borate BR, Chesler EJ, Langston MA, Saxton AM, Voy BH. Comparison of threshold selection methods for microarray gene co-expression matrices. Bmc Research Notes. 2: 240. PMID 19954523 DOI: 10.1186/1756-0500-2-240  1
2009 Baker EJ, Jay JJ, Philip VM, Zhang Y, Li Z, Kirova R, Langston MA, Chesler EJ. Ontological Discovery Environment: a system for integrating gene-phenotype associations. Genomics. 94: 377-87. PMID 19733230 DOI: 10.1016/j.ygeno.2009.08.016  1
2009 Saccone SF, Bierut LJ, Chesler EJ, Kalivas PW, Lerman C, Saccone NL, Uhl GR, Li CY, Philip VM, Edenberg HJ, Sherry ST, Feolo M, Moyzis RK, Rutter JL. Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm. Plos One. 4: e5225. PMID 19381300 DOI: 10.1371/journal.pone.0005225  1
2009 Song MJ, Lewis CK, Lance ER, Chesler EJ, Yordanova RK, Langston MA, Lodowski KH, Bergeson SE. Reconstructing generalized logical networks of transcriptional regulation in mouse brain from temporal gene expression data. Eurasip Journal On Bioinformatics & Systems Biology. 545176. PMID 19300527 DOI: 10.1155/2009/545176  1
2009 Carneiro AM, Airey DC, Thompson B, Zhu CB, Lu L, Chesler EJ, Erikson KM, Blakely RD. Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 106: 2047-52. PMID 19179283 DOI: 10.1073/pnas.0809449106  1
2008 Chesler EJ, Miller DR, Branstetter LR, Galloway LD, Jackson BL, Philip VM, Voy BH, Culiat CT, Threadgill DW, Williams RW, Churchill GA, Johnson DK, Manly KF. The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 19: 382-9. PMID 18716833 DOI: 10.1007/s00335-008-9135-8  1
2008 New J, Kendall W, Huang J, Chesler E. Dynamic visualization of coexpression in systems genetics data Ieee Transactions On Visualization and Computer Graphics. 14: 1081-1094. PMID 18599919 DOI: 10.1109/TVCG.2008.61  1
2008 Matthews DB, Chesler EJ, Cook MN, Cockroft J, Philip VM, Goldowitz D. Genetic mapping of vocalization to a series of increasing acute footshocks using B6.A consomic and B6.D2 congenic mouse strains. Behavior Genetics. 38: 417-23. PMID 18535899 DOI: 10.1007/s10519-008-9210-7  1
2008 Peirce JL, Broman KW, Lu L, Chesler EJ, Zhou G, Airey DC, Birmingham AE, Williams RW. Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis. Plos One. 3: e1977. PMID 18431467 DOI: 10.1371/journal.pone.0001977  1
2008 Hancock JM, Adams NC, Aidinis V, Blake A, Blake JA, Bogue M, Brown SDM, Chesler EJ, Davidson D, Duran C, Eppig JT, Gailus-Durner V, Gates H, Gkoutos GV, Greenaway S, et al. Integration of mouse phenome data resources (Mammalian Genome (2007) 18, 3, (157-163) DOI: 10.1007/s00335-007-9004-x) Mammalian Genome. 1-2. DOI: 10.1007/s00335-008-9099-8  1
2007 Rosen GD, Chesler EJ, Manly KF, Williams RW. An informatics approach to systems neurogenetics. Methods in Molecular Biology (Clifton, N.J.). 401: 287-303. PMID 18368372 DOI: 10.1007/978-1-59745-520-6_16  1
2007 Cook MN, Dunning JP, Wiley RG, Chesler EJ, Johnson DK, Miller DR, Goldowitz D. Neurobehavioral mutants identified in an ENU-mutagenesis project. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 559-72. PMID 17629744 DOI: 10.1007/s00335-007-9035-3  1
2007 Gatti D, Maki A, Chesler EJ, Kirova R, Kosyk O, Lu L, Manly KF, Williams RW, Perkins A, Langston MA, Threadgill DW, Rusyn I. Genome-level analysis of genetic regulation of liver gene expression networks. Hepatology (Baltimore, Md.). 46: 548-57. PMID 17542012 DOI: 10.1002/hep.21682  1
2007 Hancock JM, Adams NC, Aidinis V, Blake A, Bogue M, Brown SD, Chesler EJ, Davidson D, Duran C, Eppig JT, Gailus-Durner V, Gates H, Gkoutos GV, Greenaway S, et al. Mouse Phenotype Database Integration Consortium: integration [corrected] of mouse phenome data resources. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 157-63. PMID 17436037 DOI: 10.1007/s00335-007-9004-x  1
2007 Chesler EJ. Combining Quantitative Trait and Gene-Expression Data Bioinformatics For Geneticists: a Bioinformatics Primer For the Analysis of Genetic Data: Second Edition. 389-411. DOI: 10.1002/9780470059180.ch16  1
2007 Chesler EJ, Langston MA. Combinatorial genetic regulatory network analysis tools for high throughput transcriptomic data Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4023: 150-165.  1
2006 Voy BH, Scharff JA, Perkins AD, Saxton AM, Borate B, Chesler EJ, Branstetter LK, Langston MA. Extracting gene networks for low-dose radiation using graph theoretical algorithms. Plos Computational Biology. 2: e89. PMID 16854212 DOI: 10.1371/journal.pcbi.0020089  1
2006 Goldowitz D, Matthews DB, Hamre KM, Mittleman G, Chesler EJ, Becker HC, Lopez MF, Jones SR, Mathews TA, Miles MF, Kerns R, Grant KA. Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes. Alcoholism, Clinical and Experimental Research. 30: 1066-78. PMID 16737467 DOI: 10.1111/j.1530-0277.2006.00125.x  1
2006 Kempermann G, Chesler EJ, Lu L, Williams RW, Gage FH. Natural variation and genetic covariance in adult hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 780-5. PMID 16407118 DOI: 10.1073/pnas.0510291103  1
2006 Li H, Chen H, Bao L, Manly KF, Chesler EJ, Lu L, Wang J, Zhou M, Williams RW, Cui Y. Integrative genetic analysis of transcription modules: towards filling the gap between genetic loci and inherited traits. Human Molecular Genetics. 15: 481-92. PMID 16371421 DOI: 10.1093/hmg/ddi462  1
2006 Chesler EJ, Bystrykh L, De Haan G, Cooke MP, Su A, Manly KF, Williams RW. Reply: Normalization procedures and detection of linkage signal in genetical-genomics experiments [5] Nature Genetics. 38: 856-858. DOI: 10.1038/ng0806-856  1
2005 Johnson DK, Rinchik EM, Moustaid-Moussa N, Miller DR, Williams RW, Michaud EJ, Jablonski MM, Elberger A, Hamre K, Smeyne R, Chesler E, Goldowitz D. Phenotype screening for genetically determined age-onset disorders and increased longevity in ENU-mutagenized mice. Age (Dordrecht, Netherlands). 27: 75-90. PMID 23598606 DOI: 10.1007/s11357-005-4131-3  1
2005 Vazquez-Chona FR, Khan AN, Chan CK, Moore AN, Dash PK, Hernandez MR, Lu L, Chesler EJ, Manly KF, Williams RW, Geisert EE. Genetic networks controlling retinal injury. Molecular Vision. 11: 958-70. PMID 16288200  1
2005 Bennett B, Carosone-Link PJ, Lu L, Chesler EJ, Johnson TE. Genetics of body weight in the LXS recombinant inbred mouse strains. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 16: 764-74. PMID 16261418 DOI: 10.1007/s00335-005-0002-6  1
2005 Matthews DB, Bhave SV, Belknap JK, Brittingham C, Chesler EJ, Hitzemann RJ, Hoffmann PL, Lu L, McWeeney S, Miles MF, Tabakoff B, Williams RW. Complex genetics of interactions of alcohol and CNS function and behavior. Alcoholism, Clinical and Experimental Research. 29: 1706-19. PMID 16205371 DOI: 10.1097/01.alc.0000179209.44407.df  1
2005 Mogil JS, Miermeister F, Seifert F, Strasburg K, Zimmermann K, Reinold H, Austin JS, Bernardini N, Chesler EJ, Hofmann HA, Hordo C, Messlinger K, Nemmani KV, Rankin AL, Ritchie J, et al. Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene. Proceedings of the National Academy of Sciences of the United States of America. 102: 12938-43. PMID 16118273 DOI: 10.1073/pnas.0503264102  1
2005 Welton AR, Chesler EJ, Sturkie C, Jackson AU, Hirsch GN, Spindler KR. Identification of quantitative trait loci for susceptibility to mouse adenovirus type 1. Journal of Virology. 79: 11517-22. PMID 16103204 DOI: 10.1128/JVI.79.17.11517-11522.2005  1
2005 Baldwin NE, Chesler EJ, Kirov S, Langston MA, Snoddy JR, Williams RW, Zhang B. Computational, integrative, and comparative methods for the elucidation of genetic coexpression networks. Journal of Biomedicine & Biotechnology. 2005: 172-80. PMID 16046823 DOI: 10.1155/JBB.2005.172  1
2005 Lariviere WR, Chesler EJ, Li Z, Shang GW, Chen YN, Yu YQ, Lu ZM, Chang Y, Luo C, Li KC, Chen J. Correlations between edema and the immediate and prolonged painful consequences of inflammation: therapeutic implications? Sheng Li Xue Bao : [Acta Physiologica Sinica]. 57: 278-88. PMID 15968421  1
2005 Mhyre TR, Chesler EJ, Thiruchelvam M, Lungu C, Cory-Slechta DA, Fry JD, Richfield EK. Heritability, correlations and in silico mapping of locomotor behavior and neurochemistry in inbred strains of mice. Genes, Brain, and Behavior. 4: 209-28. PMID 15924554 DOI: 10.1111/j.1601-183X.2004.00102.x  1
2005 Li H, Lu L, Manly KF, Chesler EJ, Bao L, Wang J, Zhou M, Williams RW, Cui Y. Inferring gene transcriptional modulatory relations: a genetical genomics approach. Human Molecular Genetics. 14: 1119-25. PMID 15772094 DOI: 10.1093/hmg/ddi124  1
2005 Bystrykh L, Weersing E, Dontje B, Sutton S, Pletcher MT, Wiltshire T, Su AI, Vellenga E, Wang J, Manly KF, Lu L, Chesler EJ, Alberts R, Jansen RC, Williams RW, et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nature Genetics. 37: 225-32. PMID 15711547 DOI: 10.1038/ng1497  0.96
2005 Chesler EJ, Lu L, Shou S, Qu Y, Gu J, Wang J, Hsu HC, Mountz JD, Baldwin NE, Langston MA, Threadgill DW, Manly KF, Williams RW. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nature Genetics. 37: 233-42. PMID 15711545 DOI: 10.1038/ng1518  1
2005 Scott RE, White-Grindley E, Ruley HE, Chesler EJ, Williams RW. P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA. Journal of Cellular Physiology. 204: 99-105. PMID 15617101 DOI: 10.1002/jcp.20263  1
2005 Carlborg O, De Koning DJ, Manly KF, Chesler E, Williams RW, Haley CS. Methodological aspects of the genetic dissection of gene expression. Bioinformatics (Oxford, England). 21: 2383-93. PMID 15613385 DOI: 10.1093/bioinformatics/bti243  1
2005 Zhang Y, Abu-Khzam FN, Baldwin NE, Chesler EJ, Langston MA, Samatova NF. Genome-scale computational approaches to memory-intensive applications in systems biology Proceedings of the Acm/Ieee 2005 Supercomputing Conference, Sc'05. 2005. DOI: 10.1109/SC.2005.29  1
2004 Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, ... ... Chesler EJ, et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics. 36: 1133-7. PMID 15514660 DOI: 10.1038/ng1104-1133  0.96
2004 Chesler EJ, Williams RW. Brain gene expression: genomics and genetics. International Review of Neurobiology. 60: 59-95. PMID 15474587 DOI: 10.1016/S0074-7742(04)60003-1  1
2004 Sternberg WF, Chesler EJ, Wilson SG, Mogil JS. Acute progesterone can recruit sex-specific neurochemical mechanisms mediating swim stress-induced and kappa-opioid analgesia in mice. Hormones and Behavior. 46: 467-73. PMID 15465533 DOI: 10.1016/j.yhbeh.2004.05.007  1
2004 Kest B, Palmese CA, Juni A, Chesler EJ, Mogil JS. Mapping of a quantitative trait locus for morphine withdrawal severity. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 610-7. PMID 15457340 DOI: 10.1007/s00335-004-2367-3  1
2004 Jablonski MM, Lu L, Wang X, Chesler EJ, Carps E, Qi S, Gu J, Williams RW. The ldis1 lens mutation in RIIIS/J mice maps to chromosome 8 near cadherin 1. Molecular Vision. 10: 577-87. PMID 15343150  1
2004 Chesler EJ, Lu L, Wang J, Williams RW, Manly KF. WebQTL: rapid exploratory analysis of gene expression and genetic networks for brain and behavior. Nature Neuroscience. 7: 485-6. PMID 15114364 DOI: 10.1038/nn0504-485  1
2003 Chesler EJ, Wang J, Lu L, Qu Y, Manly KF, Williams RW. Genetic correlates of gene expression in recombinant inbred strains: a relational model system to explore neurobehavioral phenotypes. Neuroinformatics. 1: 343-57. PMID 15043220 DOI: 10.1385/NI:1:4:343  1
2003 Chesler EJ, Ritchie J, Kokayeff A, Lariviere WR, Wilson SG, Mogil JS. Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited. Pain. 106: 325-35. PMID 14659515 DOI: 10.1016/S0304-3959(03)00330-0  1
2003 Abiola O, Angel JM, Avner P, Bachmanov AA, Belknap JK, Bennett B, Blankenhorn EP, Blizard DA, Bolivar V, Brockmann GA, Buck KJ, Bureau JF, Casley WL, Chesler EJ, Cheverud JM, et al. The nature and identification of quantitative trait loci: a community's view. Nature Reviews. Genetics. 4: 911-6. PMID 14634638 DOI: 10.1038/nrg1206  1
2003 Peirce JL, Chesler EJ, Williams RW, Lu L. Genetic architecture of the mouse hippocampus: identification of gene loci with selective regional effects. Genes, Brain, and Behavior. 2: 238-52. PMID 12953790 DOI: 10.1034/j.1601-183X.2003.00030.x  1
2003 Mogil JS, Wilson SG, Chesler EJ, Rankin AL, Nemmani KV, Lariviere WR, Groce MK, Wallace MR, Kaplan L, Staud R, Ness TJ, Glover TL, Stankova M, Mayorov A, Hruby VJ, et al. The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proceedings of the National Academy of Sciences of the United States of America. 100: 4867-72. PMID 12663858 DOI: 10.1073/pnas.0730053100  1
2003 Wilson SG, Bryant CD, Lariviere WR, Olsen MS, Giles BE, Chesler EJ, Mogil JS. The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice. The Journal of Pharmacology and Experimental Therapeutics. 305: 755-64. PMID 12606637 DOI: 10.1124/jpet.102.047902  1
2003 Wilson SG, Smith SB, Chesler EJ, Melton KA, Haas JJ, Mitton B, Strasburg K, Hubert L, Rodriguez-Zas SL, Mogil JS. The heritability of antinociception: common pharmacogenetic mediation of five neurochemically distinct analgesics. The Journal of Pharmacology and Experimental Therapeutics. 304: 547-59. PMID 12538806 DOI: 10.1124/jpet.102.041889  1
2002 Chesler EJ, Wilson SG, Lariviere WR, Rodriguez-Zas SL, Mogil JS. Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive. Neuroscience and Biobehavioral Reviews. 26: 907-23. PMID 12667496 DOI: 10.1016/S0149-7634(02)00103-3  1
2002 Chesler EJ, Wilson SG, Lariviere WR, Rodriguez-Zas SL, Mogil JS. Influences of laboratory environment on behavior. Nature Neuroscience. 5: 1101-2. PMID 12403996 DOI: 10.1038/nn1102-1101  1
2002 Wilson SG, Chesler EJ, Hain H, Rankin AJ, Schwarz JZ, Call SB, Murray MR, West EE, Teuscher C, Rodriguez-Zas S, Belknap JK, Mogil JS. Identification of quantitative trait loci for chemical/inflammatory nociception in mice. Pain. 96: 385-91. PMID 11973013 DOI: 10.1016/S0304-3959(01)00489-4  1
2001 Chesler EJ, Rodriguez-Zas SL, Mogil JS. In silico mapping of mouse quantitative trait loci. Science (New York, N.Y.). 294: 2423. PMID 11752534 DOI: 10.1126/science.294.5551.2423a  1
2001 Lariviere WR, Chesler EJ, Mogil JS. Transgenic studies of pain and analgesia: mutation or background genotype? The Journal of Pharmacology and Experimental Therapeutics. 297: 467-73. PMID 11303031  1
2000 Chesler EJ, Juraska JM. Acute administration of estrogen and progesterone impairs the acquisition of the spatial morris water maze in ovariectomized rats. Hormones and Behavior. 38: 234-42. PMID 11104641 DOI: 10.1006/hbeh.2000.1626  1
2000 Mogil JS, Chesler EJ, Wilson SG, Juraska JM, Sternberg WF. Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype. Neuroscience and Biobehavioral Reviews. 24: 375-89. PMID 10781697 DOI: 10.1016/S0149-7634(00)00015-4  1
1996 Chesler EJ, Salamone JD. Effects of acute and repeated clozapine injections on cholinomimetic-induced vacuous jaw movements. Pharmacology, Biochemistry, and Behavior. 54: 619-24. PMID 8743638 DOI: 10.1016/0091-3057(95)02280-5  1
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