Yasser Heakal, Ph.D. - Related publications

Affiliations: 
2009 Pennsylvania State University, State College, PA, United States 
Area:
Pharmacology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Liu J, Miao X, Xiao B, Huang J, Tao X, Zhang J, Zhao H, Pan Y, Wang H, Gao G, Xiao GG. Obg-Like ATPase 1 Enhances Chemoresistance of Breast Cancer Activation of TGF-β/Smad Axis Cascades. Frontiers in Pharmacology. 11: 666. PMID 32528278 DOI: 10.3389/fphar.2020.00666   
2020 Ryu YS, Shin S, An HG, Kwon TU, Baek HS, Kwon YJ, Chun YJ. Synergistic Induction of Apoptosis by the Combination of an Axl Inhibitor and Auranofin in Human Breast Cancer Cells. Biomolecules & Therapeutics. PMID 32536618 DOI: 10.4062/biomolther.2020.051   
2020 Gu H, Peng Y, Chen Y. An Emerging Therapeutic Approach by Targeting Myoferlin (MYOF) for Malignant Tumors. Current Topics in Medicinal Chemistry. PMID 32552653 DOI: 10.2174/1568026620666200618123436   
2020 Liu Y, Ma L, Shangguan F, Zhao X, Wang W, Gao Z, Zhou H, Qu G, Huang Y, An J, Xue J, Yang S, Cao Q. LAIR-1 suppresses cell growth of ovarian cancer cell via the PI3K-AKT-mTOR pathway. Aging. 12. PMID 32628130 DOI: 10.18632/aging.103589   
2020 Zhang L, Zhang J, Ni C. Silencing of lncRNA PART1 inhibits proliferation, invasion and migration of breast cancer cells and promotes the efficacy of cisplatin in breast cancer cells. General Physiology and Biophysics. PMID 32700682 DOI: 10.4149/gpb_2020008   
2020 Nozaki Y, Motomura H, Tamori S, Kimura Y, Onaga C, Kanai S, Ishihara Y, Ozaki A, Hara Y, Harada Y, Mano Y, Sato T, Sato K, Sasaki K, Ishiguro H, et al. High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients. Plos One. 15: e0235747. PMID 32658903 DOI: 10.1371/journal.pone.0235747   
2020 Sai Mani G, Anchi P, Sunkari S, Donthiboina K, Godugu C, Shankaraiah N, Kamal A. Synthesis of (Z)-3-(arylamino)-1-(3-phenylimidazo[1,5-a]pyridin-1-yl)prop-2-en-1-ones as potential cytotoxic agents. Bioorganic & Medicinal Chemistry Letters. 127432. PMID 32717368 DOI: 10.1016/j.bmcl.2020.127432   
2020 Louca M, Stylianopoulos T, Gkretsi V. Ras Suppressor-1 (RSU1) in Cancer Cell Metastasis: A Tale of a Tumor Suppressor. International Journal of Molecular Sciences. 21. PMID 32517326 DOI: 10.3390/ijms21114076   
2020 Li K, Liu T, Chen J, Ni H, Li W. Survivin in breast cancer-derived exosomes activates fibroblasts by upregulating SOD1, whose feedback promotes cancer proliferation and metastasis. The Journal of Biological Chemistry. PMID 32709750 DOI: 10.1074/jbc.RA120.013805   
2020 Zheng YW, Gao PF, Ma MZ, Chen Y, Li CY. Role of ubiquitin-conjugating enzyme E2T in the carcinogenesis and progression of pancreatic cancer. Oncology Letters. 20: 1462-1468. PMID 32724389 DOI: 10.3892/ol.2020.11644   
2020 Zhang H, Zhu T, Fu R, Peng Y, Jing P, Xu W, Wang H, Li S, Shu Z, Yin Y, Zhang X. Combination of Detoxified Pneumolysin Derivative ΔA146Ply and Berbamine as a Treatment Approach for Breast Cancer. Molecular Therapy Oncolytics. 18: 247-261. PMID 32728613 DOI: 10.1016/j.omto.2020.06.015   
2020 Javed S, Bhattacharyya S, Bagga R, Srinivasan R. Insulin growth factor-1 pathway in cervical carcinoma cancer stem cells. Molecular and Cellular Biochemistry. PMID 32602015 DOI: 10.1007/s11010-020-03807-6   
2020 Zhang M, He S, Ma X, Ye Y, Wang G, Zhuang J, Song Y, Xia W. GINS2 affects cell viability, cell apoptosis, and cell cycle progression of pancreatic cancer cells via MAPK/ERK pathway. Journal of Cancer. 11: 4662-4670. PMID 32626512 DOI: 10.7150/jca.38386   
2020 Chen X, Yin T, Zhang B, Sun B, Chen J, Xiao T, Wang B, Li M, Yang J, Fan X. Inhibitory effects of brusatol delivered using glycosaminoglycan‑placental chondroitin sulfate A‑modified nanoparticles on the proliferation, migration and invasion of cancer cells. International Journal of Molecular Medicine. 46: 817-827. PMID 32626948 DOI: 10.3892/ijmm.2020.4627   
2020 Kumar RS, Almansour AI, Arumugam N, Mohammad F, Kumar RR. Mechanistic Exploration of Novel Spiropyrrolidine Heterocyclic Hybrids as Anticancer Agents. Frontiers in Chemistry. 8: 465. PMID 32582638 DOI: 10.3389/fchem.2020.00465   
2020 An G, Park S, Lee M, Lim W, Song G. Antiproliferative Effect of 4-Methylumbelliferone in Epithelial Ovarian Cancer Cells Is Mediated by Disruption of Intracellular Homeostasis and Regulation of PI3K/AKT and MAPK Signaling. Pharmaceutics. 12. PMID 32645961 DOI: 10.3390/pharmaceutics12070640   
2020 Zhang P, Yan Y, Wang J, Dong X, Zhang G, Zeng Y, Liu Z. An Anti-Cancer Peptide LVTX-8 Inhibits the Proliferation and Migration of Lung Tumor Cells by Regulating Causal Genes' Expression in p53-Related Pathways. Toxins. 12. PMID 32498425 DOI: 10.3390/toxins12060367   
2020 Jeong M, Jung E, Lee YH, Seo JK, Ahn S, Koh D, Lim Y, Shin SY. A Novel Synthetic Compound (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile Inhibits TNFα-Induced Expression via EGR-1 Downregulation in MDA-MB-231 Human Breast Cancer Cells. International Journal of Molecular Sciences. 21. PMID 32708426 DOI: 10.3390/ijms21145080   
2020 Wang B, Sun L, Yuan Z, Tao Z. Wee1 kinase inhibitor AZD1775 potentiates CD8+ T cell-dependent antitumour activity via dendritic cell activation following a single high dose of irradiation. Medical Oncology (Northwood, London, England). 37: 66. PMID 32696094 DOI: 10.1007/s12032-020-01390-w   
2020 Liu Y, Qin P, Wu R, Du L, Li F. ERas regulates cell proliferation and epithelial-mesenchymal transition by affecting Erk/Akt signaling pathway in pancreatic cancer. Human Cell. PMID 32700262 DOI: 10.1007/s13577-020-00401-2   
2020 Geng Q, Chen X, Chen N. Transmembrane protein 88 exerts a tumor-inhibitory role in thyroid cancer through restriction of Wnt/β-catenin signaling. Experimental Cell Research. 112193. PMID 32710906 DOI: 10.1016/j.yexcr.2020.112193   
2020 Kim DC, Jin H, Lee JS, Son E, Lee GW, Kim HJ. P2YR has a significant correlation with Notch-4 in patients with breast cancer. Oncology Letters. 20: 647-654. PMID 32565989 DOI: 10.3892/ol.2020.11630   
2020 Tao H, Chen X, Du Z, Ding K. Corn silk crude polysaccharide exerts anti-pancreatic cancer activity by blocking the EGFR/PI3K/AKT/CREB signaling pathway. Food & Function. PMID 32696775 DOI: 10.1039/d0fo00403k   
2020 Gao Y, Liu P, Shi R. Anlotinib as a molecular targeted therapy for tumors. Oncology Letters. 20: 1001-1014. PMID 32724339 DOI: 10.3892/ol.2020.11685   
2020 Shurbaji S, G Anlar G, A Hussein E, Elzatahry A, C Yalcin H. Effect of Flow-Induced Shear Stress in Nanomaterial Uptake by Cells: Focus on Targeted Anti-Cancer Therapy. Cancers. 12. PMID 32708521 DOI: 10.3390/cancers12071916   
2020 Ma W, Zhang Q, Li X, Ma Y, Liu Y, Hu S, Zhou Z, Zhang R, Du K, Syed A, Yao X, Chen P. IPM712, a vanillin derivative as potential antitumor agents, displays better antitumor activity in colorectal cancers cell lines. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105464. PMID 32668313 DOI: 10.1016/j.ejps.2020.105464   
2020 Xie H, Liang JJ, Wang YL, Hu TX, Wang JY, Yang RH, Yan JK, Zhang QR, Xu X, Liu HM, Ke Y. The design, synthesis and anti-tumor mechanism study of new androgen receptor degrader. European Journal of Medicinal Chemistry. 204: 112512. PMID 32736229 DOI: 10.1016/j.ejmech.2020.112512   
2020 Wei JR, Dong J, Li L. Cancer-associated fibroblasts-derived gamma-glutamyltransferase 5 promotes tumor growth and drug resistance in lung adenocarcinoma. Aging. 12. PMID 32640421 DOI: 10.18632/aging.103429   
2020 Agarwal S, Maekawa T. Nano delivery of natural substances as prospective autophagy modulators in glioblastoma. Nanomedicine : Nanotechnology, Biology, and Medicine. 102270. PMID 32702467 DOI: 10.1016/j.nano.2020.102270   
2020 Liu Q, Hodge J, Wang J, Wang Y, Wang L, Singh U, Li Y, Yao Y, Wang D, Ai W, Nagarkatti P, Chen H, Xu P, Murphy EA, Fan D. Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation. Theranostics. 10: 8365-8381. PMID 32724475 DOI: 10.7150/thno.45395   
2020 Shafei MA, Forshaw T, Davis J, Flemban A, Qualtrough D, Dean S, Perks C, Dong M, Newman R, Conway ME. BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer. Oncotarget. 11: 1971-1987. PMID 32523652 DOI: 10.18632/oncotarget.27607   
2020 Das B, Kundu CN. Anti-Cancer Stem Cells Potentiality of an Anti-Malarial Agent Quinacrine: An Old Wine in a New Bottle. Anti-Cancer Agents in Medicinal Chemistry. PMID 32698746 DOI: 10.2174/1871520620666200721123046   
2020 Czarnomysy R, Radomska D, Muszyńska A, Hermanowicz JM, Prokop I, Bielawska A, Bielawski K. Evaluation of the Anticancer Activities of Novel Transition Metal Complexes with Berenil and Nitroimidazole. Molecules (Basel, Switzerland). 25. PMID 32575817 DOI: 10.3390/molecules25122860   
2020 Zhang W, Liao K, Liu D. MiRNA-12129 Suppresses Cell Proliferation and Block Cell Cycle Progression by Targeting SIRT1 in GASTRIC Cancer. Technology in Cancer Research & Treatment. 19: 1533033820928144. PMID 32508267 DOI: 10.1177/1533033820928144   
2020 Xu H, Zhou Z, Li B. Natural compound Alternol as a novel therapeutic for prostate cancer treatment. American Journal of Clinical and Experimental Urology. 8: 76-80. PMID 32699806   
2020 Cadena M, DeLuna F, Baryeh K, Sun LZ, Ye JY. Prostate Cancer Epithelial Mesenchymal Transition by TGF-β1 exposure monitored with a Photonic Crystal Biosensor. Proceedings of Spie--the International Society For Optical Engineering. 11251. PMID 32632340 DOI: 10.1117/12.2544113   
2020 Ma J, Li L, Du J, Pan C, Zhang C, Chen Y. Placenta-specific protein 1 enhances liver metastatic potential and is associated with the PI3K/AKT/NF-κB signaling pathway in colorectal cancer. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (Ecp). PMID 32701605 DOI: 10.1097/CEJ.0000000000000611   
2020 Zhao Y, He J, Li Y, Xu M, Peng X, Mao J, Xu B, Cui H. PHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells. Biomed Research International. 2020: 6507510. PMID 32596345 DOI: 10.1155/2020/6507510   
2020 Murali P, Johnson BP, Lu Z, Climer L, Scott DA, Foulquier F, Oprea-Ilies G, Lupashin V, Drake RR, Abbott KL. Novel role for the Golgi membrane protein TMEM165 in control of migration and invasion for breast carcinoma. Oncotarget. 11: 2747-2762. PMID 32733646 DOI: 10.18632/oncotarget.27668   
2020 Ren G, Hao X, Yang S, Chen J, Qiu G, Ang KP, Mohd Tamrin MI. 10H-3,6-Diazaphenothiazines triggered the mitochondrial-dependent and cell death receptor-dependent apoptosis pathways and further increased the chemosensitivity of MCF-7 breast cancer cells via inhibition of AKT1 pathways. Journal of Biochemical and Molecular Toxicology. e22544. PMID 32619082 DOI: 10.1002/jbt.22544   
2020 Cha YJ, Koo JS. Role of Tumor-Associated Myeloid Cells in Breast Cancer. Cells. 9. PMID 32726950 DOI: 10.3390/cells9081785   
2020 Ma Z, Cai Y, Zhang L, Tian C, Lyu L. LINC00319 Promotes Cervical Cancer Progression Via Targeting miR-147a/IGF1R Pathway. Cancer Biotherapy & Radiopharmaceuticals. PMID 32644822 DOI: 10.1089/cbr.2020.3722   
2020 Gürpınar T, Kosova F, Kurt FO, Cambaz SU, Yücel AT, Umur N, Tuğlu MI. Effect of geldanamycin on the expression of the matrix molecules and angiogenetic factors in a gastric cancer cell line. Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission. 1-6. PMID 32573272 DOI: 10.1080/10520295.2020.1772507   
2020 Mahmood N, Arakelian A, Muller WJ, Szyf M, Rabbani SA. An enhanced chemopreventive effect of methyl donor S-adenosylmethionine in combination with 25-hydroxyvitamin D in blocking mammary tumor growth and metastasis. Bone Research. 8: 28. PMID 32714613 DOI: 10.1038/s41413-020-0103-6   
2020 Zhang P, Liu L, Zhang L, He X, Xu X, Lu Y, Li F. Runx2 is required for activity of CD44/CD24 breast cancer stem cell in breast cancer development. American Journal of Translational Research. 12: 2305-2318. PMID 32509221   
2020 Zhen X, Choi HS, Kim JH, Kim SL, Liu R, Ko YC, Yun BS, Lee DS. Caudatin Isolated from Inhibits Breast Cancer Stem Cell Formation via a GR/YAP Signaling. Biomolecules. 10. PMID 32570844 DOI: 10.3390/biom10060925   
2020 Garvey CM, Lau R, Sanchez A, Sun RX, Fong EJ, Doche ME, Chen O, Jusuf A, Lenz HJ, Larson B, Mumenthaler SM. Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance. Cancers. 12. PMID 32481658 DOI: 10.3390/cancers12061393   
2020 Chen AC, Xu R, Wang T, Wei J, Yang XY, Liu CX, Lei G, Lyerly HK, Heiland T, Hartman ZC. HER2-LAMP vaccines effectively traffic to endolysosomal compartments and generate enhanced polyfunctional T cell responses that induce complete tumor regression. Journal For Immunotherapy of Cancer. 8. PMID 32532838 DOI: 10.1136/jitc-2019-000258   
2020 Masilamani AP, Dettmer-Monaco V, Monaco G, Cathomen T, Kuckuck I, Schultze-Seemann S, Huber N, Wolf P. An Anti-PSMA Immunotoxin Reduces Mcl-1 and Bcl2A1 and Specifically Induces in Combination with the BAD-Like BH3 Mimetic ABT-737 Apoptosis in Prostate Cancer Cells. Cancers. 12. PMID 32580291 DOI: 10.3390/cancers12061648   
2020 Ren N, Chen L, Li B, Rankin GO, Chen YC, Tu Y. Purified Tea ( (L.) ) Flower Saponins Induce the p53-Dependent Intrinsic Apoptosis of Cisplatin-Resistant Ovarian Cancer Cells. International Journal of Molecular Sciences. 21. PMID 32560563 DOI: 10.3390/ijms21124324