Year |
Citation |
Score |
2020 |
Karpus WJ. Cytokines and Chemokines in the Pathogenesis of Experimental Autoimmune Encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 204: 316-326. PMID 31907274 DOI: 10.4049/jimmunol.1900914 |
0.548 |
|
2019 |
Hsu M, Rayasam A, Kijak JA, Choi YH, Harding JS, Marcus SA, Karpus WJ, Sandor M, Fabry Z. Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells. Nature Communications. 10: 229. PMID 30651548 DOI: 10.1038/S41467-018-08163-0 |
0.363 |
|
2013 |
Karpus WJ. Inflammatory macrophage migration in experimental autoimmune encephalomyelitis. Methods in Molecular Biology (Clifton, N.J.). 1013: 161-9. PMID 23625498 DOI: 10.1007/978-1-62703-426-5_10 |
0.603 |
|
2013 |
Sugiura Y, Kamdar K, Khakpour S, Young G, Karpus WJ, DePaolo RW. TLR1-induced chemokine production is critical for mucosal immunity against Yersinia enterocolitica. Mucosal Immunology. 6: 1101-9. PMID 23443468 DOI: 10.1038/Mi.2013.5 |
0.781 |
|
2012 |
Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK. Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mechanisms of Development. 129: 193-207. PMID 22982455 DOI: 10.1016/J.Mod.2012.08.002 |
0.344 |
|
2011 |
Reynolds ND, Lukacs NW, Long N, Karpus WJ. Delta-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 187: 2803-13. PMID 21788444 DOI: 10.4049/Jimmunol.1100160 |
0.842 |
|
2011 |
Forde EA, Dogan RN, Karpus WJ. CCR4 contributes to the pathogenesis of experimental autoimmune encephalomyelitis by regulating inflammatory macrophage function. Journal of Neuroimmunology. 236: 17-26. PMID 21575994 DOI: 10.1016/J.Jneuroim.2011.04.008 |
0.791 |
|
2011 |
Dogan RN, Long N, Forde E, Dennis K, Kohm AP, Miller SD, Karpus WJ. CCL22 regulates experimental autoimmune encephalomyelitis by controlling inflammatory macrophage accumulation and effector function. Journal of Leukocyte Biology. 89: 93-104. PMID 20940325 DOI: 10.1189/Jlb.0810442 |
0.786 |
|
2010 |
Shahrara S, Pickens SR, Mandelin AM, Karpus WJ, Huang Q, Kolls JK, Pope RM. IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2/monocyte chemoattractant protein-1 induction. Journal of Immunology (Baltimore, Md. : 1950). 184: 4479-87. PMID 20228199 DOI: 10.4049/Jimmunol.0901942 |
0.388 |
|
2010 |
Miller SD, Karpus WJ, Davidson TS. Experimental autoimmune encephalomyelitis in the mouse. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 15.1. PMID 20143314 DOI: 10.1002/0471142735.im1501s88 |
0.397 |
|
2009 |
Blasko E, Haskell CA, Leung S, Gualtieri G, Halks-Miller M, Mahmoudi M, Dennis MK, Prossnitz ER, Karpus WJ, Horuk R. Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis. Journal of Neuroimmunology. 214: 67-77. PMID 19664827 DOI: 10.1016/J.Jneuroim.2009.06.023 |
0.509 |
|
2009 |
Malkani RG, Tallman M, Gottardi-Littell N, Karpus W, Marszalek L, Variakojis D, Kaden B, Walker M, Levy RM, Raizer JJ. Bing-Neel syndrome: an illustrative case and a comprehensive review of the published literature. Journal of Neuro-Oncology. 96: 301-12. PMID 19618118 DOI: 10.1007/S11060-009-9968-3 |
0.313 |
|
2009 |
Elhofy A, Depaolo RW, Lira SA, Lukacs NW, Karpus WJ. Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 213: 91-9. PMID 19535153 DOI: 10.1016/J.Jneuroim.2009.05.011 |
0.822 |
|
2008 |
Thompson WL, Karpus WJ, Van Eldik LJ. MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult. Journal of Neuroinflammation. 5: 35. PMID 18706086 DOI: 10.1186/1742-2094-5-35 |
0.456 |
|
2008 |
Karpus WJ, Reynolds N, Behanna HA, Van Eldik LJ, Watterson DM. Inhibition of experimental autoimmune encephalomyelitis by a novel small molecular weight proinflammatory cytokine suppressing drug. Journal of Neuroimmunology. 203: 73-8. PMID 18678415 DOI: 10.1016/J.Jneuroim.2008.06.039 |
0.626 |
|
2008 |
Dogan RN, Elhofy A, Karpus WJ. Production of CCL2 by central nervous system cells regulates development of murine experimental autoimmune encephalomyelitis through the recruitment of TNF- and iNOS-expressing macrophages and myeloid dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 7376-84. PMID 18490737 DOI: 10.4049/Jimmunol.180.11.7376 |
0.651 |
|
2007 |
Miller SD, Karpus WJ. Experimental autoimmune encephalomyelitis in the mouse. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 15.1. PMID 18432984 DOI: 10.1002/0471142735.Im1501S77 |
0.345 |
|
2007 |
Karpus WJ. T cell receptor and CD3 antibody crossreactivity opens new research and veterinary medicine opportunities. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 71: 976-7. PMID 18023064 DOI: 10.1002/Cyto.A.20500 |
0.378 |
|
2007 |
Matsumoto K, Yu S, Jia Y, Ahmed MR, Viswakarma N, Sarkar J, Kashireddy PV, Rao MS, Karpus W, Gonzalez FJ, Reddy JK. Critical role for transcription coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein/TRAP220 in liver regeneration and PPARalpha ligand-induced liver tumor development. The Journal of Biological Chemistry. 282: 17053-60. PMID 17438330 DOI: 10.1074/Jbc.M701956200 |
0.388 |
|
2007 |
Bennett JL, Elhofy A, Charo I, Miller SD, Dal Canto MC, Karpus WJ. CCR2 regulates development of Theiler's murine encephalomyelitis virus-induced demyelinating disease. Viral Immunology. 20: 19-33. PMID 17425418 DOI: 10.1089/Vim.2006.0068 |
0.848 |
|
2006 |
Karpus WJ, Kennedy KJ, Fife BT, Bennett JL, Dal Canto MC, Kunkel SL, Lukacs NW. Anti-CCL2 treatment inhibits Theiler's murine encephalomyelitis virus-induced demyelinating disease. Journal of Neurovirology. 12: 251-61. PMID 16966216 DOI: 10.1080/13550280600873819 |
0.836 |
|
2005 |
Depaolo RW, Lathan R, Rollins BJ, Karpus WJ. The chemokine CCL2 is required for control of murine gastric Salmonella enterica infection. Infection and Immunity. 73: 6514-22. PMID 16177325 DOI: 10.1128/Iai.73.10.6514-6522.2005 |
0.773 |
|
2005 |
Elhofy A, Wang J, Tani M, Fife BT, Kennedy KJ, Bennett J, Huang D, Ransohoff RM, Karpus WJ. Transgenic expression of CCL2 in the central nervous system prevents experimental autoimmune encephalomyelitis. Journal of Leukocyte Biology. 77: 229-37. PMID 15539456 DOI: 10.1189/Jlb.0804465 |
0.842 |
|
2005 |
Carpentier PA, Begolka WS, Olson JK, Elhofy A, Karpus WJ, Miller SD. Differential activation of astrocytes by innate and adaptive immune stimuli. Glia. 49: 360-74. PMID 15538753 DOI: 10.1002/Glia.20117 |
0.487 |
|
2004 |
DePaolo RW, Lathan R, Karpus WJ. CCR5 regulates high dose oral tolerance by modulating CC chemokine ligand 2 levels in the GALT. Journal of Immunology (Baltimore, Md. : 1950). 173: 314-20. PMID 15210789 DOI: 10.4049/Jimmunol.173.1.314 |
0.773 |
|
2004 |
Dogan RN, Karpus WJ. Chemokines and chemokine receptors in autoimmune encephalomyelitis as a model for central nervous system inflammatory disease regulation. Frontiers in Bioscience : a Journal and Virtual Library. 9: 1500-5. PMID 14977561 DOI: 10.2741/1284 |
0.58 |
|
2003 |
Bennett JL, Elhofy A, Canto MC, Tani M, Ransohoff RM, Karpus WJ. CCL2 transgene expression in the central nervous system directs diffuse infiltration of CD45(high)CD11b(+) monocytes and enhanced Theiler's murine encephalomyelitis virus-induced demyelinating disease. Journal of Neurovirology. 9: 623-36. PMID 14602575 DOI: 10.1080/13550280390247551 |
0.848 |
|
2003 |
Monaghan SA, Peterson LC, James C, Marszalek L, Khoong A, Bachta DJ, Karpus WJ, Goolsby CL. Pan B-cell markers are not redundant in analysis of chronic lymphocytic leukemia (CLL). Cytometry. Part B, Clinical Cytometry. 56: 30-42. PMID 14582135 DOI: 10.1002/Cyto.B.10049 |
0.303 |
|
2003 |
DePaolo RW, Rollins BJ, Kuziel W, Karpus WJ. CC chemokine ligand 2 and its receptor regulate mucosal production of IL-12 and TGF-beta in high dose oral tolerance. Journal of Immunology (Baltimore, Md. : 1950). 171: 3560-7. PMID 14500652 DOI: 10.4049/Jimmunol.171.7.3560 |
0.788 |
|
2003 |
Karpus WJ, Fife BT, Kennedy KJ. Immunoneutralization of chemokines for the prevention and treatment of central nervous system autoimmune disease. Methods (San Diego, Calif.). 29: 362-8. PMID 12725803 DOI: 10.1016/S1046-2023(02)00360-2 |
0.776 |
|
2002 |
Elhofy A, Kennedy KJ, Fife BT, Karpus WJ. Regulation of experimental autoimmune encephalomyelitis by chemokines and chemokine receptors. Immunologic Research. 25: 167-75. PMID 11999170 DOI: 10.1385/Ir:25:2:167 |
0.755 |
|
2001 |
Fife BT, Paniagua MC, Lukacs NW, Kunkel SL, Karpus WJ. Selective CC chemokine receptor expression by central nervous system-infiltrating encephalitogenic T cells during experimental autoimmune encephalomyelitis Journal of Neuroscience Research. 66: 705-714. PMID 11746391 DOI: 10.1002/Jnr.10037 |
0.772 |
|
2001 |
Karpus WJ, Fife BT. Keystone Symposia: chemokines and chemokine receptors. 16-21st February 2001, Taos, NM, USA Expert Opinion On Biological Therapy. 1: 549-553. PMID 11727525 DOI: 10.1517/14712598.1.3.549 |
0.703 |
|
2001 |
Karpus WJ. Chemokines and central nervous system disorders Journal of Neurovirology. 7: 493-500. PMID 11704881 DOI: 10.1080/135502801753248079 |
0.55 |
|
2001 |
Fife BT, Kennedy KJ, Paniagua MC, Lukacs NW, Kunkel SL, Luster AD, Karpus WJ. CXL10 (IFN-γ-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis Journal of Immunology. 166: 7617-7624. PMID 11390519 DOI: 10.4049/Jimmunol.166.12.7617 |
0.789 |
|
2000 |
Fife BT, Huffnagle GB, Kuziel WA, Karpus WJ. CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis Journal of Experimental Medicine. 192: 899-905. PMID 10993920 DOI: 10.1084/Jem.192.6.899 |
0.823 |
|
1999 |
Karpus WJ, Kennedy KJ, Fife BT, Hoffman LM. Chemokine Regulation of Immune-mediated Demyelinating Disease. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 40: 183-189. PMID 11406697 DOI: 10.1093/Ilar.40.4.183 |
0.785 |
|
1999 |
Huffman LM, Fife BT, Begolka WS, Miller SD, Karpus WJ. Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease Journal of Neurovirology. 5: 635-642. PMID 10602404 DOI: 10.3109/13550289909021292 |
0.731 |
|
1999 |
Kennedy KJ, Karpus WJ. Role of chemokines in the regulation of Th1/Th2 and autoimmune encephalomyelitis Journal of Clinical Immunology. 19: 273-279. PMID 10535603 DOI: 10.1023/A:1020535423465 |
0.62 |
|
1999 |
Karpus WJ. Chemokine regulation of inflammatory-mediated nervous system diseases Journal of Neurovirology. 5: 1-2. PMID 10190684 DOI: 10.3109/13550289909029739 |
0.526 |
|
1998 |
Hoffman LM, Karpus WJ. Chemokine regulation of CNS T-cell infiltration in experimental autoimmune encephalomyelitis Research in Immunology. 149: 790-794. PMID 9923634 DOI: 10.1016/S0923-2494(99)80006-6 |
0.464 |
|
1998 |
Kennedy KJ, Strieter RM, Kunkel SL, Lukacs NW, Karpus WJ. Acute and relapsing experimental autoimmune encephalomyelitis are regulated by differential expression of the CC chemokines macrophage inflammatory protein-1α and monocyte chemotactic protein-1 Journal of Neuroimmunology. 92: 98-108. PMID 9916884 DOI: 10.1016/S0165-5728(98)00187-8 |
0.579 |
|
1998 |
Karpus WJ, Ransohoff RM. Cutting edge commentary: Chemokine regulation of experimental autoimmune encephalomyelitis: Temporal and spatial expression patterns govern disease pathogenesis Journal of Immunology. 161: 2667-2671. PMID 9743321 |
0.428 |
|
1998 |
Karpus WJ, Kennedy KJ, Kunkel SL, Lukacs NW. Monocyte chemotactic protein 1 regulates oral tolerance induction inhibition of T helper cell 1-related cytokines Journal of Experimental Medicine. 187: 733-741. PMID 9480983 DOI: 10.1084/Jem.187.5.733 |
0.562 |
|
1998 |
Fife B, Karpus W. Encephalitogenic T cell CC chemokine receptor expression during the pathogenesis of autoimmune encephalomyelitis Journal of Neuroimmunology. 90: 21. DOI: 10.1016/S0165-5728(98)91304-2 |
0.718 |
|
1997 |
Karpus WJ, Kennedy KJ. MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphoctye differentiation Journal of Leukocyte Biology. 62: 681-687. PMID 9365124 |
0.49 |
|
1997 |
Kennedy KJ, Smith WS, Miller SD, Karpus WJ. Induction of Antigen-Specific Tolerance for the Treatment of Ongoing, Relapsing Autoimmune Encephalomyelitis: A Comparison between Oral and Peripheral Tolerance Journal of Immunology. 159: 1036-1044. PMID 9218627 |
0.344 |
|
1997 |
Lukacs NW, Chensue SW, Karpus WJ, Lincoln P, Keefer C, Strieter RM, Kunkel SL. C-C chemokines differentially alter interleukin-4 production from lymphocytes American Journal of Pathology. 150: 1861-1868. PMID 9137108 |
0.359 |
|
1997 |
Karpus WJ, Lukacs NW, Kennedy KJ, Smith WS, Hurst SD, Barrett TA. Differential CC chemokine-induced enhancement of T helper cell cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 158: 4129-36. PMID 9126972 |
0.425 |
|
1997 |
Karpus WJ, Kennedy KJ. MIP-1alpha and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation. Journal of Leukocyte Biology. 62: 681-687. DOI: 10.1002/Jlb.62.5.681 |
0.556 |
|
1996 |
Karpus WJ, Kennedy KJ, Smith WS, Miller SD. Inhibition of relapsing experimental autoimmune encephalomyelitis in SJL mice by feeding the immunodominant PLP139-151 peptide Journal of Neuroscience Research. 45: 410-423. PMID 8872901 DOI: 10.1002/(Sici)1097-4547(19960815)45:4<410::Aid-Jnr10>3.0.Co;2-4 |
0.424 |
|
1996 |
Pope JG, Karpus WJ, Vanderlugt C, Miller SD. Flow cytometric and functional analyses of central nervous system-infiltrating cells in SJL/J mice with Theiler's virus-induced demyelinating disease: Evidence for a CD4+ T cell-mediated pathology Journal of Immunology. 156: 4050-4058. PMID 8621948 |
0.45 |
|
1996 |
Karpus WJ, Lukacs NW. The role of chemokines in oral tolerance: Abrogation of nonresponsiveness by treatment with antimonocyte chemotactic protein-1 Annals of the New York Academy of Sciences. 778: 133-144. PMID 8610967 DOI: 10.1111/J.1749-6632.1996.Tb21122.X |
0.509 |
|
1996 |
Karpus WJ, Kennedy KJ, Smith WS. Comparison of oral and peripheral tolerance for the prevention and treatment of chronic-relapsing EAE Faseb Journal. 10. |
0.452 |
|
1996 |
Smith WS, Hurst SD, Barrett TA, Karpus WJ. Chemokine regulation of T cell cytokine production Faseb Journal. 10: A1485. |
0.368 |
|
1995 |
Karpus WJ, Pope JG, Peterson JD, Dal Canto MC, Miller SD. Inhibition of Theiler's virus-mediated demyelination by peripheral immune tolerance induction. Journal of Immunology (Baltimore, Md. : 1950). 155: 947-57. PMID 7608570 |
0.57 |
|
1995 |
Karpus WJ, Lukacs NW, McRae BL, Strieter RM, Kunkel SL, Miller SD. An important role for the chemokine macrophage inflammatory protein-1α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis Journal of Immunology. 155: 5003-5010. PMID 7594507 |
0.53 |
|
1995 |
Miller SD, McRae BL, Vanderlugt CL, Nikcevich KM, Pope JG, Pope L, Karpus WJ. Evolution of the T-cell repertoire during the course of experimental immunemediated demyelinating diseases Immunological Reviews. 224-244. PMID 7590815 DOI: 10.1111/J.1600-065X.1995.Tb00071.X |
0.578 |
|
1995 |
McRae BL, Nikcevich KM, Karpus WJ, Hurst SD, Miller SD. Differential recognition of peptide analogs by naive verses activated PLP 139-151-specific CD4+ T cells. Journal of Neuroimmunology. 60: 17-28. PMID 7543908 DOI: 10.1016/0165-5728(95)00048-7 |
0.494 |
|
1994 |
Karpus WJ, Peterson JD, Miller SD. Anergy in vivo: down-regulation of antigen-specific CD4+ Th1 but not Th2 cytokine responses. International Immunology. 6: 721-30. PMID 8080842 DOI: 10.1093/Intimm/6.5.721 |
0.483 |
|
1994 |
Gerety SJ, Karpus WJ, Cubbon AR, Goswami RG, Rundell MK, Peterson JD, Miller SD. Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. V. Mapping of a dominant immunopathologic VP2 T cell epitope in susceptible SJL/J mice. Journal of Immunology (Baltimore, Md. : 1950). 152: 908-18. PMID 7904291 |
0.54 |
|
1994 |
Miller SD, Karpus WJ. The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases Trends in Immunology. 15: 356-361. DOI: 10.1016/0167-5699(94)90173-2 |
0.576 |
|
1994 |
Karpus WJ, Peterson JD, Pope JG, Miller SD. Prevention of TMEV-induced demyelinating disease by in vivo tolerance induction Journal of Neuroimmunology. 54: 171. DOI: 10.1016/0165-5728(94)90378-6 |
0.444 |
|
1993 |
Peterson JD, Karpus WJ, Clatch RJ, Miller SD. Split tolerance of Th1 and Th2 cells in tolerance to Theiler's murine encephalomyelitis virus. European Journal of Immunology. 23: 46-55. PMID 8419186 DOI: 10.1002/Eji.1830230109 |
0.469 |
|
1993 |
Dal Canto MC, Karpus WJ, Peterson JD, Miller SD. TREATMENT OF THEILERʼS MURINE ENCEPHALOMYELITIS VIRUS-INDUCED DEMYELINATING DISEASE BY IN VIVO TOLERANCE INDUCTION Journal of Neuropathology and Experimental Neurology. 52: 312. DOI: 10.1097/00005072-199305000-00207 |
0.421 |
|
1992 |
Karpus WJ, Gould KE, Swanborg RH. CD4+ suppressor cells of autoimmune encephalomyelitis respond to T cell receptor‐associated determinants on effector cells by interleukin‐4 secretion European Journal of Immunology. 22: 1757-1763. PMID 1378016 DOI: 10.1002/Eji.1830220714 |
0.33 |
|
1992 |
Stevens DB, Karpus WJ, Gould KE, Swanborg RH. Studies of Vβ8 T cell receptor peptide treatment in experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 37: 123-129. PMID 1372325 DOI: 10.1016/0165-5728(92)90163-F |
0.312 |
|
1992 |
Miller SD, Tan LJ, Pope L, Mcrae BL, Karpus WJ. Antigen-specific tolerance as a therapy for experimental autoimmune encephalomyelitis International Reviews of Immunology. 9: 203-222. PMID 1285061 DOI: 10.3109/08830189209061791 |
0.473 |
|
1991 |
Karpus WJ, Swanborg RH. Protection against experimental autoimmune encephalomyelitis requires both CD4+ T suppressor cells and myelin basic protein-primed B cells Journal of Neuroimmunology. 33: 173-177. PMID 1712365 DOI: 10.1016/0165-5728(91)90061-B |
0.401 |
|
1989 |
Hayosh NS, Karpus WJ, Swanborg RH. Effector cells of autoimmune encephalomyelitis in the rat belong to the CD4-positive, OX22-adherent T cell subset Journal of Neuroimmunology. 25: 57-61. PMID 2584391 DOI: 10.1016/0165-5728(89)90086-6 |
0.388 |
|
1989 |
Karpus WJ, Swanborg RH. CD4+ suppressor cells differentially affect the production of IFN-γ by effector cells of experimental autoimmune encephalomyelitis Journal of Immunology. 143: 3492-3497. PMID 2573635 |
0.36 |
|
1988 |
Karpus WJ, Konkol RJ, Killen JA. Central catecholamine neurotoxin administration. 1. Immunological changes associated with the suppression of experimental autoimmune encephalomyelitis Journal of Neuroimmunology. 18: 61-73. PMID 3126218 DOI: 10.1016/0165-5728(88)90135-X |
0.378 |
|
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