Patrick W. Mantyh - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Neuroscience Biology, Pathology, Oncology

192 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Guedon JM, Longo G, Majuta LA, Thomspon ML, Fealk MN, Mantyh PW. Dissociation between the relief of skeletal pain behaviors and skin hypersensitivity in a model of bone cancer pain. Pain. 157: 1239-47. PMID 27186713 DOI: 10.1097/j.pain.0000000000000514  1
2015 Thompson ML, Jimenez-Andrade JM, Mantyh PW. Sclerostin Immunoreactivity Increases in Cortical Bone Osteocytes and Decreases in Articular Cartilage Chondrocytes in Aging Mice. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. PMID 26701970 DOI: 10.1369/0022155415626499  1
2015 Kim JY, Tillu DV, Quinn TL, Mejia GL, Shy A, Asiedu MN, Murad E, Schumann AP, Totsch SK, Sorge RE, Mantyh PW, Dussor G, Price TJ. Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6307-17. PMID 25904784 DOI: 10.1523/JNEUROSCI.3481-14.2015  1
2015 Majuta LA, Longo G, Fealk MN, McCaffrey G, Mantyh PW. Orthopedic surgery and bone fracture pain are both significantly attenuated by sustained blockade of nerve growth factor. Pain. 156: 157-65. PMID 25599311 DOI: 10.1016/j.pain.0000000000000017  1
2015 Mantyh PW. Bone-related nociception Musculoskeletal Pain: Basic Mechanisms and Implications 1
2015 Jimenez-Andrade JM, Mantyh PW. Bone cancer pain: Translation of preclinical studies to human clinical trials Pain Models: Translational Relevance and Applications 1
2014 McCaffrey G, Thompson ML, Majuta L, Fealk MN, Chartier S, Longo G, Mantyh PW. NGF blockade at early times during bone cancer development attenuates bone destruction and increases limb use. Cancer Research. 74: 7014-23. PMID 25287160 DOI: 10.1158/0008-5472.CAN-14-1220  1
2014 Chartier SR, Thompson ML, Longo G, Fealk MN, Majuta LA, Mantyh PW. Exuberant sprouting of sensory and sympathetic nerve fibers in nonhealed bone fractures and the generation and maintenance of chronic skeletal pain. Pain. 155: 2323-36. PMID 25196264 DOI: 10.1016/j.pain.2014.08.026  1
2014 Mantyh PW. Bone cancer pain: from mechanism to therapy. Current Opinion in Supportive and Palliative Care. 8: 83-90. PMID 24792411 DOI: 10.1097/SPC.0000000000000048  1
2014 Mantyh PW. The neurobiology of skeletal pain. The European Journal of Neuroscience. 39: 508-19. PMID 24494689 DOI: 10.1111/ejn.12462  1
2014 Mantyh PW, Thompson ML, Chartier S, Fealk M. Bone cancer: Current opinion in palliative care Bone Cancer: Primary Bone Cancers and Bone Metastases: Second Edition. 579-589. DOI: 10.1016/B978-0-12-416721-6.00048-0  1
2013 Lozano-Ondoua AN, Hanlon KE, Symons-Liguori AM, Largent-Milnes TM, Havelin JJ, Ferland HL, Chandramouli A, Owusu-Ankomah M, Nikolich-Zugich T, Bloom AP, Jimenez-Andrade JM, King T, Porreca F, Nelson MA, Mantyh PW, et al. Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 92-107. PMID 22903605 DOI: 10.1002/jbmr.1732  1
2012 Reilly RM, McDonald HA, Puttfarcken PS, Joshi SK, Lewis L, Pai M, Franklin PH, Segreti JA, Neelands TR, Han P, Chen J, Mantyh PW, Ghilardi JR, Turner TM, Voight EA, et al. Pharmacology of modality-specific transient receptor potential vanilloid-1 antagonists that do not alter body temperature. The Journal of Pharmacology and Experimental Therapeutics. 342: 416-28. PMID 22570364 DOI: 10.1124/jpet.111.190314  1
2012 Jimenez-Andrade JM, Mantyh PW. Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice. Arthritis Research & Therapy. 14: R101. PMID 22548760 DOI: 10.1186/ar3826  1
2012 Ghilardi JR, Freeman KT, Jimenez-Andrade JM, Coughlin KA, Kaczmarska MJ, Castaneda-Corral G, Bloom AP, Kuskowski MA, Mantyh PW. Neuroplasticity of sensory and sympathetic nerve fibers in a mouse model of a painful arthritic joint. Arthritis and Rheumatism. 64: 2223-32. PMID 22246649 DOI: 10.1002/art.34385  1
2012 Jimenez-Andrade JM, Mantyh WG, Bloom AP, Freeman KT, Ghilardi JR, Kuskowski MA, Mantyh PW. The effect of aging on the density of the sensory nerve fiber innervation of bone and acute skeletal pain. Neurobiology of Aging. 33: 921-32. PMID 20947214 DOI: 10.1016/j.neurobiolaging.2010.08.008  1
2012 Mantyh PW. Reply Arthritis and Rheumatism. 64: 3825-3826. DOI: 10.1002/art.34621  1
2011 Jimenez-Andrade JM, Ghilardi JR, Castañeda-Corral G, Kuskowski MA, Mantyh PW. Preventive or late administration of anti-NGF therapy attenuates tumor-induced nerve sprouting, neuroma formation, and cancer pain. Pain. 152: 2564-74. PMID 21907491 DOI: 10.1016/j.pain.2011.07.020  1
2011 Mantyh PW, Koltzenburg M, Mendell LM, Tive L, Shelton DL. Antagonism of nerve growth factor-TrkA signaling and the relief of pain. Anesthesiology. 115: 189-204. PMID 21602663 DOI: 10.1097/ALN.0b013e31821b1ac5  1
2011 Bloom AP, Jimenez-Andrade JM, Taylor RN, Castañeda-Corral G, Kaczmarska MJ, Freeman KT, Coughlin KA, Ghilardi JR, Kuskowski MA, Mantyh PW. Breast cancer-induced bone remodeling, skeletal pain, and sprouting of sensory nerve fibers. The Journal of Pain : Official Journal of the American Pain Society. 12: 698-711. PMID 21497141 DOI: 10.1016/j.jpain.2010.12.016  1
2011 Castañeda-Corral G, Jimenez-Andrade JM, Bloom AP, Taylor RN, Mantyh WG, Kaczmarska MJ, Ghilardi JR, Mantyh PW. The majority of myelinated and unmyelinated sensory nerve fibers that innervate bone express the tropomyosin receptor kinase A. Neuroscience. 178: 196-207. PMID 21277945 DOI: 10.1016/j.neuroscience.2011.01.039  1
2011 Ghilardi JR, Freeman KT, Jimenez-Andrade JM, Mantyh WG, Bloom AP, Bouhana KS, Trollinger D, Winkler J, Lee P, Andrews SW, Kuskowski MA, Mantyh PW. Sustained blockade of neurotrophin receptors TrkA, TrkB and TrkC reduces non-malignant skeletal pain but not the maintenance of sensory and sympathetic nerve fibers. Bone. 48: 389-98. PMID 20854944 DOI: 10.1016/j.bone.2010.09.019  1
2010 Ghilardi JR, Freeman KT, Jimenez-Andrade JM, Mantyh WG, Bloom AP, Kuskowski MA, Mantyh PW. Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer pain. Molecular Pain. 6: 87. PMID 21138586 DOI: 10.1186/1744-8069-6-87  1
2010 Jimenez-Andrade JM, Bloom AP, Stake JI, Mantyh WG, Taylor RN, Freeman KT, Ghilardi JR, Kuskowski MA, Mantyh PW. Pathological sprouting of adult nociceptors in chronic prostate cancer-induced bone pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14649-56. PMID 21048122 DOI: 10.1523/JNEUROSCI.3300-10.2010  1
2010 Mantyh WG, Jimenez-Andrade JM, Stake JI, Bloom AP, Kaczmarska MJ, Taylor RN, Freeman KT, Ghilardi JR, Kuskowski MA, Mantyh PW. Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain. Neuroscience. 171: 588-98. PMID 20851743 DOI: 10.1016/j.neuroscience.2010.08.056  1
2010 Jimenez-Andrade JM, Mantyh WG, Bloom AP, Ferng AS, Geffre CP, Mantyh PW. Bone cancer pain. Annals of the New York Academy of Sciences. 1198: 173-81. PMID 20536932 DOI: 10.1111/j.1749-6632.2009.05429.x  1
2010 Lozano-Ondoua AN, Wright C, Vardanyan A, King T, Largent-Milnes TM, Nelson M, Jimenez-Andrade JM, Mantyh PW, Vanderah TW. A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. Life Sciences. 86: 646-53. PMID 20176037 DOI: 10.1016/j.lfs.2010.02.014  1
2010 Jimenez-Andrade JM, Mantyh WG, Bloom AP, Xu H, Ferng AS, Dussor G, Vanderah TW, Mantyh PW. A phenotypically restricted set of primary afferent nerve fibers innervate the bone versus skin: therapeutic opportunity for treating skeletal pain. Bone. 46: 306-13. PMID 19766746 DOI: 10.1016/j.bone.2009.09.013  1
2010 Mantyh PW, Yaksh TL. An integrative approach to the control of cancer pain The Neurobiology of Pain: (Molecular and Cellular Neurobiology). DOI: 10.1093/acprof:oso/9780198515616.003.0015  1
2010 Yaksh TL, Mantyh PW. Spinal delivery of drugs in pain control The Neurobiology of Pain: (Molecular and Cellular Neurobiology). DOI: 10.1093/acprof:oso/9780198515616.003.0008  1
2010 Jimenez-Andrade JM, Mantyh PW. Neuropeptides Internalization Encyclopedia of Neuroscience. 867-871. DOI: 10.1016/B978-008045046-9.01460-1  1
2010 Herrera M, Jimenez-Andrade JM, Vardanyan M, Mantyh PW. Malignant skeletal pain: Mechanisms and potential therapeutic opportunities Bone Cancer. 321-332. DOI: 10.1016/B978-0-12-374895-9.00027-X  1
2009 Jimenez-Andrade JM, Bloom AP, Mantyh WG, Koewler NJ, Freeman KT, Delong D, Ghilardi JR, Kuskowski MA, Mantyh PW. Capsaicin-sensitive sensory nerve fibers contribute to the generation and maintenance of skeletal fracture pain. Neuroscience. 162: 1244-54. PMID 19486928 DOI: 10.1016/j.neuroscience.2009.05.065  1
2009 Bove SE, Flatters SJ, Inglis JJ, Mantyh PW. New advances in musculoskeletal pain. Brain Research Reviews. 60: 187-201. PMID 19166876 DOI: 10.1016/j.brainresrev.2008.12.012  1
2009 Honore P, Chandran P, Hernandez G, Gauvin DM, Mikusa JP, Zhong C, Joshi SK, Ghilardi JR, Sevcik MA, Fryer RM, Segreti JA, Banfor PN, Marsh K, Neelands T, Bayburt E, ... ... Mantyh PW, et al. Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia. Pain. 142: 27-35. PMID 19135797 DOI: 10.1016/j.pain.2008.11.004  1
2008 Halvorson KG, Sevcik MA, Ghilardi JR, Sullivan LJ, Koewler NJ, Bauss F, Mantyh PW. Intravenous ibandronate rapidly reduces pain, neurochemical indices of central sensitization, tumor burden, and skeletal destruction in a mouse model of bone cancer. Journal of Pain and Symptom Management. 36: 289-303. PMID 18411018 DOI: 10.1016/j.jpainsymman.2007.10.005  1
2008 Jimenez-Andrade JM, Herrera MB, Ghilardi JR, Vardanyan M, Melemedjian OK, Mantyh PW. Vascularization of the dorsal root ganglia and peripheral nerve of the mouse: implications for chemical-induced peripheral sensory neuropathies. Molecular Pain. 4: 10. PMID 18353190 DOI: 10.1186/1744-8069-4-10  1
2008 Freeman KT, Koewler NJ, Jimenez-Andrade JM, Buus RJ, Herrera MB, Martin CD, Ghilardi JR, Kuskowski MA, Mantyh PW. A fracture pain model in the rat: adaptation of a closed femur fracture model to study skeletal pain. Anesthesiology. 108: 473-83. PMID 18292685 DOI: 10.1097/ALN.0b013e3181649351  1
2007 Martin CD, Jimenez-Andrade JM, Ghilardi JR, Mantyh PW. Organization of a unique net-like meshwork of CGRP+ sensory fibers in the mouse periosteum: implications for the generation and maintenance of bone fracture pain. Neuroscience Letters. 427: 148-52. PMID 17950532 DOI: 10.1016/j.neulet.2007.08.055  1
2007 Peters CM, Jimenez-Andrade JM, Kuskowski MA, Ghilardi JR, Mantyh PW. An evolving cellular pathology occurs in dorsal root ganglia, peripheral nerve and spinal cord following intravenous administration of paclitaxel in the rat. Brain Research. 1168: 46-59. PMID 17698044 DOI: 10.1016/j.brainres.2007.06.066  1
2007 Jimenez-Andrade JM, Martin CD, Koewler NJ, Freeman KT, Sullivan LJ, Halvorson KG, Barthold CM, Peters CM, Buus RJ, Ghilardi JR, Lewis JL, Kuskowski MA, Mantyh PW. Nerve growth factor sequestering therapy attenuates non-malignant skeletal pain following fracture. Pain. 133: 183-96. PMID 17693023 DOI: 10.1016/j.pain.2007.06.016  1
2007 Tracey I, Mantyh PW. The cerebral signature for pain perception and its modulation. Neuron. 55: 377-91. PMID 17678852 DOI: 10.1016/j.neuron.2007.07.012  1
2007 Koewler NJ, Freeman KT, Buus RJ, Herrera MB, Jimenez-Andrade JM, Ghilardi JR, Peters CM, Sullivan LJ, Kuskowski MA, Lewis JL, Mantyh PW. Effects of a monoclonal antibody raised against nerve growth factor on skeletal pain and bone healing after fracture of the C57BL/6J mouse femur. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1732-42. PMID 17638576 DOI: 10.1359/jbmr.070711  1
2007 Budai D, Khasabov SG, Mantyh PW, Simone DA. NK-1 receptors modulate the excitability of ON cells in the rostral ventromedial medulla. Journal of Neurophysiology. 97: 1388-95. PMID 17182914 DOI: 10.1152/jn.00450.2006  1
2007 Peters CM, Jimenez-Andrade JM, Jonas BM, Sevcik MA, Koewler NJ, Ghilardi JR, Wong GY, Mantyh PW. Intravenous paclitaxel administration in the rat induces a peripheral sensory neuropathy characterized by macrophage infiltration and injury to sensory neurons and their supporting cells. Experimental Neurology. 203: 42-54. PMID 17005179 DOI: 10.1016/j.expneurol.2006.07.022  1
2006 Mantyh PW. Cancer pain and its impact on diagnosis, survival and quality of life. Nature Reviews. Neuroscience. 7: 797-809. PMID 16988655 DOI: 10.1038/nrn1914  1
2006 Sevcik MA, Jonas BM, Lindsay TH, Halvorson KG, Ghilardi JR, Kuskowski MA, Mukherjee P, Maggio JE, Mantyh PW. Endogenous opioids inhibit early-stage pancreatic pain in a mouse model of pancreatic cancer. Gastroenterology. 131: 900-10. PMID 16952558 DOI: 10.1053/j.gastro.2006.06.021  1
2006 Halvorson KG, Sevcik MA, Ghilardi JR, Rosol TJ, Mantyh PW. Similarities and differences in tumor growth, skeletal remodeling and pain in an osteolytic and osteoblastic model of bone cancer. The Clinical Journal of Pain. 22: 587-600. PMID 16926574 DOI: 10.1097/01.ajp.0000210902.67849.e6  1
2006 Jimenez-Andrade JM, Peters CM, Mejia NA, Ghilardi JR, Kuskowski MA, Mantyh PW. Sensory neurons and their supporting cells located in the trigeminal, thoracic and lumbar ganglia differentially express markers of injury following intravenous administration of paclitaxel in the rat. Neuroscience Letters. 405: 62-7. PMID 16854522 DOI: 10.1016/j.neulet.2006.06.043  1
2006 Allen JW, Mantyh PW, Horais K, Tozier N, Rogers SD, Ghilardi JR, Cizkova D, Grafe MR, Richter P, Lappi DA, Yaksh TL. Safety evaluation of intrathecal substance P-saporin, a targeted neurotoxin, in dogs. Toxicological Sciences : An Official Journal of the Society of Toxicology. 91: 286-98. PMID 16500924 DOI: 10.1093/toxsci/kfj143  1
2006 Lindsay TH, Halvorson KG, Peters CM, Ghilardi JR, Kuskowski MA, Wong GY, Mantyh PW. A quantitative analysis of the sensory and sympathetic innervation of the mouse pancreas. Neuroscience. 137: 1417-26. PMID 16388907 DOI: 10.1016/j.neuroscience.2005.10.055  1
2006 Mantyh PW. Pain Due to Bone Metastases: New Research Issues and Their Clinical Implications Cancer Pain. 75-84. DOI: 10.1016/B978-0-7216-0261-5.50012-0  1
2005 Lindsay TH, Jonas BM, Sevcik MA, Kubota K, Halvorson KG, Ghilardi JR, Kuskowski MA, Stelow EB, Mukherjee P, Gendler SJ, Wong GY, Mantyh PW. Pancreatic cancer pain and its correlation with changes in tumor vasculature, macrophage infiltration, neuronal innervation, body weight and disease progression. Pain. 119: 233-46. PMID 16298491 DOI: 10.1016/j.pain.2005.10.019  1
2005 Sevcik MA, Ghilardi JR, Halvorson KG, Lindsay TH, Kubota K, Mantyh PW. Analgesic efficacy of bradykinin B1 antagonists in a murine bone cancer pain model. The Journal of Pain : Official Journal of the American Pain Society. 6: 771-5. PMID 16275602 DOI: 10.1016/j.jpain.2005.06.010  1
2005 Halvorson KG, Kubota K, Sevcik MA, Lindsay TH, Sotillo JE, Ghilardi JR, Rosol TJ, Boustany L, Shelton DL, Mantyh PW. A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in bone. Cancer Research. 65: 9426-35. PMID 16230406 DOI: 10.1158/0008-5472.CAN-05-0826  1
2005 Goblirsch M, Lynch C, Mathews W, Manivel JC, Mantyh PW, Clohisy DR. Radiation treatment decreases bone cancer pain through direct effect on tumor cells. Radiation Research. 164: 400-8. PMID 16187742 DOI: 10.1667/RR3439.1  1
2005 Luger NM, Mach DB, Sevcik MA, Mantyh PW. Bone cancer pain: from model to mechanism to therapy. Journal of Pain and Symptom Management. 29: S32-46. PMID 15907645 DOI: 10.1016/j.jpainsymman.2005.01.008  1
2005 Sevcik MA, Ghilardi JR, Peters CM, Lindsay TH, Halvorson KG, Jonas BM, Kubota K, Kuskowski MA, Boustany L, Shelton DL, Mantyh PW. Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitization. Pain. 115: 128-41. PMID 15836976 DOI: 10.1016/j.pain.2005.02.022  1
2005 Peters CM, Ghilardi JR, Keyser CP, Kubota K, Lindsay TH, Luger NM, Mach DB, Schwei MJ, Sevcik MA, Mantyh PW. Tumor-induced injury of primary afferent sensory nerve fibers in bone cancer pain. Experimental Neurology. 193: 85-100. PMID 15817267 DOI: 10.1016/j.expneurol.2004.11.028  1
2005 Ghilardi JR, Röhrich H, Lindsay TH, Sevcik MA, Schwei MJ, Kubota K, Halvorson KG, Poblete J, Chaplan SR, Dubin AE, Carruthers NI, Swanson D, Kuskowski M, Flores CM, Julius D, ... Mantyh PW, et al. Selective blockade of the capsaicin receptor TRPV1 attenuates bone cancer pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3126-31. PMID 15788769 DOI: 10.1523/JNEUROSCI.3815-04.2005  1
2005 Sabino MA, Mantyh PW. Pathophysiology of bone cancer pain. The Journal of Supportive Oncology. 3: 15-24. PMID 15724942  1
2005 Khasabov SG, Ghilardi JR, Mantyh PW, Simone DA. Spinal neurons that express NK-1 receptors modulate descending controls that project through the dorsolateral funiculus. Journal of Neurophysiology. 93: 998-1006. PMID 15456795 DOI: 10.1152/jn.01160.2003  1
2004 Clohisy DR, Mantyh PW. Bone cancer pain and the role of RANKL/OPG Journal of Musculoskeletal Neuronal Interactions. 4: 293-300. PMID 15615497  1
2004 Mantyh PW. A mechanism-based understanding of bone cancer pain. Novartis Foundation Symposium. 261: 194-214; discussion . PMID 15469052  1
2004 Mantyh PW, Hunt SP. Setting the tone: superficial dorsal horn projection neurons regulate pain sensitivity. Trends in Neurosciences. 27: 582-4. PMID 15374667 DOI: 10.1016/j.tins.2004.07.007  1
2004 Sevcik MA, Luger NM, Mach DB, Sabino MA, Peters CM, Ghilardi JR, Schwei MJ, Röhrich H, De Felipe C, Kuskowski MA, Mantyh PW. Bone cancer pain: the effects of the bisphosphonate alendronate on pain, skeletal remodeling, tumor growth and tumor necrosis. Pain. 111: 169-80. PMID 15327821 DOI: 10.1016/j.pain.2004.06.015  1
2004 Mantyh PW, Hunt SP. Mechanisms that generate and maintain bone cancer pain. Novartis Foundation Symposium. 260: 221-38; discussion 2. PMID 15283453  1
2004 Peters CM, Lindsay TH, Pomonis JD, Luger NM, Ghilardi JR, Sevcik MA, Mantyh PW. Endothelin and the tumorigenic component of bone cancer pain. Neuroscience. 126: 1043-52. PMID 15207337 DOI: 10.1016/j.neuroscience.2004.04.027  1
2004 Yezierski RP, Yu CG, Mantyh PW, Vierck CJ, Lappi DA. Spinal neurons involved in the generation of at-level pain following spinal injury in the rat. Neuroscience Letters. 361: 232-6. PMID 15135936 DOI: 10.1016/j.neulet.2003.12.035  1
2004 Ghilardi JR, Svensson CI, Rogers SD, Yaksh TL, Mantyh PW. Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2727-32. PMID 15028765 DOI: 10.1523/JNEUROSCI.5054-03.2004  1
2004 Goblirsch M, Mathews W, Lynch C, Alaei P, Gerbi BJ, Mantyh PW, Clohisy DR. Radiation Treatment Decreases Bone Cancer Pain, Osteolysis and Tumor Size Radiation Research. 161: 228-234. PMID 14731066 DOI: 10.1667/RR3108  1
2004 Sabino MAC, Mantyh PW. Clinically related behavioral models: Bone cancer pain Drug Discovery Today: Disease Models. 1: 127-134. DOI: 10.1016/j.ddmod.2004.09.007  1
2003 Morcuende S, Gadd CA, Peters M, Moss A, Harris EA, Sheasby A, Fisher AS, De Felipe C, Mantyh PW, Rupniak NM, Giese KP, Hunt SP. Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice. The European Journal of Neuroscience. 18: 1828-36. PMID 14622216 DOI: 10.1046/j.1460-9568.2003.02911.x  1
2003 Clohisy DR, Mantyh PW. Bone cancer pain. Clinical Orthopaedics and Related Research. S279-88. PMID 14600620 DOI: 10.1097/01.blo.0000093059.96273.56  1
2003 Egnaczyk GF, Pomonis JD, Schmidt JA, Rogers SD, Peters C, Ghilardi JR, Mantyh PW, Maggio JE. Proteomic analysis of the reactive phenotype of astrocytes following endothelin-1 exposure. Proteomics. 3: 689-98. PMID 12748948 DOI: 10.1002/pmic.200300407  1
2003 Peters CM, Rogers SD, Pomonis JD, Egnaczyk GF, Keyser CP, Schmidt JA, Ghilardi JR, Maggio JE, Mantyh PW, Egnazyck GF. Endothelin receptor expression in the normal and injured spinal cord: potential involvement in injury-induced ischemia and gliosis. Experimental Neurology. 180: 1-13. PMID 12668144 DOI: 10.1016/S0014-4886(02)00023-7  1
2003 Sabino MA, Luger NM, Mach DB, Rogers SD, Schwei MJ, Mantyh PW. Different tumors in bone each give rise to a distinct pattern of skeletal destruction, bone cancer-related pain behaviors and neurochemical changes in the central nervous system. International Journal of Cancer. Journal International Du Cancer. 104: 550-8. PMID 12594809 DOI: 10.1002/ijc.10999  1
2003 Clohisy DR, Mantyh PW. Bone cancer pain. Cancer. 97: 866-73. PMID 12548588 DOI: 10.1002/cncr.11144  1
2003 Rogers SD, Peters CM, Pomonis JD, Hagiwara H, Ghilardi JR, Mantyh PW. Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS. Glia. 41: 180-90. PMID 12509808 DOI: 10.1002/glia.10173  1
2002 Sabino MC, Ghilardi JR, Feia KJ, Jongen JL, Keyser CP, Luger NM, Mach DB, Peters CM, Rogers SD, Schwei MJ, De Filipe C, Mantyh PW. The involvement of prostaglandins in tumorigenesis, tumor-induced osteolysis and bone cancer pain. Journal of Musculoskeletal & Neuronal Interactions. 2: 561-2. PMID 15758394  1
2002 Honoré P, Kamp EH, Rogers SD, Gebhart GF, Mantyh PW. Activation of lamina I spinal cord neurons that express the substance P receptor in visceral nociception and hyperalgesia. The Journal of Pain : Official Journal of the American Pain Society. 3: 3-11. PMID 14622848 DOI: 10.1054/jpai.2002.27001  1
2002 Mantyh PW. Neurobiology of substance P and the NK1 receptor. The Journal of Clinical Psychiatry. 63: 6-10. PMID 12562137  1
2002 Sabino MA, Ghilardi JR, Jongen JL, Keyser CP, Luger NM, Mach DB, Peters CM, Rogers SD, Schwei MJ, de Felipe C, Mantyh PW. Simultaneous reduction in cancer pain, bone destruction, and tumor growth by selective inhibition of cyclooxygenase-2. Cancer Research. 62: 7343-9. PMID 12499278  1
2002 Luger NM, Sabino MA, Schwei MJ, Mach DB, Pomonis JD, Keyser CP, Rathbun M, Clohisy DR, Honore P, Yaksh TL, Mantyh PW. Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs inflammatory pain. Pain. 99: 397-406. PMID 12406514 DOI: 10.1016/S0304-3959(02)00102-1  1
2002 Khasabov SG, Rogers SD, Ghilardi JR, Peters CM, Mantyh PW, Simone DA. Spinal neurons that possess the substance P receptor are required for the development of central sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9086-98. PMID 12388616  1
2002 Mach DB, Rogers SD, Sabino MC, Luger NM, Schwei MJ, Pomonis JD, Keyser CP, Clohisy DR, Adams DJ, O'Leary P, Mantyh PW. Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience. 113: 155-66. PMID 12123694 DOI: 10.1016/S0306-4522(02)00165-3  1
2002 Esler WP, Marshall JR, Stimson ER, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE. Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: mechanistic implications for apoE4 enhanced amyloid burden and risk for Alzheimer's disease. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 9: 1-12. PMID 12000192  1
2002 Mantyh PW, Clohisy DR, Koltzenburg M, Hunt SP. Molecular mechanisms of cancer pain. Nature Reviews. Cancer. 2: 201-9. PMID 11990856 DOI: 10.1038/nrc747  1
2002 Mantyh PW. A mechanism based understanding of cancer pain. Pain. 96: 1-2. PMID 11932054 DOI: 10.1016/S0304-3959(01)00482-1  1
2002 Marshall JR, Stimson ER, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE. Noninvasive imaging of peripherally injected Alzheimer's disease type synthetic A beta amyloid in vivo. Bioconjugate Chemistry. 13: 276-84. PMID 11906265 DOI: 10.1021/bc010066z  1
2002 Sabino MA, Honore P, Rogers SD, Mach DB, Luger NM, Mantyh PW. Tooth extraction-induced internalization of the substance P receptor in trigeminal nucleus and spinal cord neurons: imaging the neurochemistry of dental pain. Pain. 95: 175-86. PMID 11790480 DOI: 10.1016/S0304-3959(01)00397-9  1
2001 Khasabov SG, Cain DM, Thong D, Mantyh PW, Simone DA. Enhanced responses of spinal dorsal horn neurons to heat and cold stimuli following mild freeze injury to the skin Journal of Neurophysiology. 86: 986-996. PMID 11495966  1
2001 Mantyh PW, Yaksh TL. Sensory neurons are PARtial to pain. Nature Medicine. 7: 772-3. PMID 11433334 DOI: 10.1038/89880  1
2001 Luger NM, Honore P, Sabino MA, Schwei MJ, Rogers SD, Mach DB, Clohisy DR, Mantyh PW. Osteoprotegerin diminishes advanced bone cancer pain. Cancer Research. 61: 4038-47. PMID 11358823  1
2001 Hunt SP, Mantyh PW. The molecular dynamics of pain control. Nature Reviews. Neuroscience. 2: 83-91. PMID 11252998 DOI: 10.1038/35053509  1
2001 Pomonis JD, Rogers SD, Peters CM, Ghilardi JR, Mantyh PW. Expression and localization of endothelin receptors: implications for the involvement of peripheral glia in nociception. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 999-1006. PMID 11157085  1
2000 Honoré P, Schwei J, Rogers SD, Salak-Johnson JL, Finke MP, Ramnaraine ML, Clohisy DR, Mantyh PW. Cellular and neurochemical remodeling of the spinal cord in bone cancer pain. Progress in Brain Research. 129: 389-97. PMID 11098706 DOI: 10.1016/S0079-6123(00)29030-4  1
2000 Honoré P, Menning PM, Rogers SD, Nichols ML, Mantyh PW. Neurochemical plasticity in persistent inflammatory pain. Progress in Brain Research. 129: 357-63. PMID 11098703 DOI: 10.1016/S0079-6123(00)29027-4  1
2000 Esler WP, Felix AM, Stimson ER, Lachenmann MJ, Ghilardi JR, Lu YA, Vinters HV, Mantyh PW, Lee JP, Maggio JE. Activation barriers to structural transition determine deposition rates of Alzheimer's disease a beta amyloid. Journal of Structural Biology. 130: 174-83. PMID 10940224 DOI: 10.1006/jsbi.2000.4276  1
2000 Honore P, Rogers SD, Schwei MJ, Salak-Johnson JL, Luger NM, Sabino MC, Clohisy DR, Mantyh PW. Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience. 98: 585-98. PMID 10869852 DOI: 10.1016/S0306-4522(00)00110-X  1
2000 Esler WP, Stimson ER, Jennings JM, Vinters HV, Ghilardi JR, Lee JP, Mantyh PW, Maggio JE. Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism. Biochemistry. 39: 6288-95. PMID 10828941 DOI: 10.1021/bi992933h  1
2000 Honore P, Luger NM, Sabino MA, Schwei MJ, Rogers SD, Mach DB, O'keefe PF, Ramnaraine ML, Clohisy DR, Mantyh PW. Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord. Nature Medicine. 6: 521-8. PMID 10802707 DOI: 10.1038/74999  1
2000 Honore P, Mantyh PW. Bone Cancer Pain: From Mechanism to Model to Therapy Pain Medicine. 1: 303-309.  1
1999 Schwei MJ, Honore P, Rogers SD, Salak-Johnson JL, Finke MP, Ramnaraine ML, Clohisy DR, Mantyh PW. Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10886-97. PMID 10594070  1
1999 Nichols ML, Allen BJ, Rogers SD, Ghilardi JR, Honore P, Luger NM, Finke MP, Li J, Lappi DA, Simone DA, Mantyh PW. Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science (New York, N.Y.). 286: 1558-61. PMID 10567262 DOI: 10.1126/science.286.5444.1558  1
1999 Oyamada H, Takatsuji K, Senba E, Mantyh PW, Tohyama M. Postnatal development of NK1, NK2, and NK3 neurokinin receptors expression in the rat retina. Brain Research. Developmental Brain Research. 117: 59-70. PMID 10536233 DOI: 10.1016/S0165-3806(99)00099-1  1
1999 Trafton JA, Abbadie C, Marchand S, Mantyh PW, Basbaum AI. Spinal opioid analgesia: how critical is the regulation of substance P signaling? The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9642-53. PMID 10531466  1
1999 Esler WP, Stimson ER, Mantyh PW, Maggio JE. Deposition of soluble amyloid-β onto amyloid templates: With application for the identification of amyloid fibril extension inhibitors Methods in Enzymology. 309: 350-374. PMID 10507035 DOI: 10.1016/S0076-6879(99)09025-4  1
1999 Honor P, Menning PM, Rogers SD, Nichols ML, Basbaum AI, Besson JM, Mantyh PW. Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7670-8. PMID 10460273  1
1999 Tseng BP, Esler WP, Clish CB, Stimson ER, Ghilardi JR, Vinters HV, Mantyh PW, Lee JP, Maggio JE. Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations. Biochemistry. 38: 10424-31. PMID 10441137 DOI: 10.1021/bi990718v  1
1999 Esler WP, Stimson ER, Fishman JB, Ghilardi JR, Vinters HV, Mantyh PW, Maggio JE. Stereochemical specificity of Alzheimer's disease beta-peptide assembly. Biopolymers. 49: 505-14. PMID 10193196 DOI: 10.1002/(SICI)1097-0282(199905)49:6<505::AID-BIP8>3.0.CO;2-I  1
1999 Allen BJ, Li J, Menning PM, Rogers SD, Ghilardi J, Mantyh PW, Simone DA. Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury. Journal of Neurophysiology. 81: 1379-90. PMID 10085363  1
1999 O'Hare E, Weldon DT, Mantyh PW, Ghilardi JR, Finke MP, Kuskowski MA, Maggio JE, Shephard RA, Cleary J. Delayed behavioral effects following intrahippocampal injection of aggregated A beta (1-42). Brain Research. 815: 1-10. PMID 9974116 DOI: 10.1016/S0006-8993(98)01002-6  1
1998 Mantyh PW, Hunt SP. Hot peppers and pain. Neuron. 21: 644-5. PMID 9808445  1
1998 Cao YQ, Mantyh PW, Carlson EJ, Gillespie AM, Epstein CJ, Basbaum AI. Primary afferent tachykinins are required to experience moderate to intense pain. Nature. 392: 390-4. PMID 9537322 DOI: 10.1038/32897  1
1998 Weldon DT, Rogers SD, Ghilardi JR, Finke MP, Cleary JP, O'Hare E, Esler WP, Maggio JE, Mantyh PW. Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2161-73. PMID 9482801  1
1998 O'Hare E, Weldon DT, Ghilardi JR, Estler WP, Maggio JE, Mantyh PW, Cleary J. Bilateral intrahippocampal aggregated beta-amyloid injection alters alternating lever cyclic-ratio schedule behavior in the rat Faseb Journal. 12.  1
1997 Mantyh PW, Rogers SD, Honore P, Allen BJ, Ghilardi JR, Li J, Daughters RS, Lappi DA, Wiley RG, Simone DA. Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor. Science (New York, N.Y.). 278: 275-9. PMID 9323204 DOI: 10.1126/science.278.5336.275  1
1997 Abbadie C, Trafton J, Liu H, Mantyh PW, Basbaum AI. Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8049-60. PMID 9315923  1
1997 Weldon DT, Maggio JE, Mantyh PW. New insights into the neuropathology and cell biology of Alzheimer's disease Geriatrics. 52. PMID 9307579  1
1997 Allen BJ, Rogers SD, Ghilardi JR, Menning PM, Kuskowski MA, Basbaum AI, Simone DA, Mantyh PW. Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5921-7. PMID 9221788  1
1997 Rogers SD, Demaster E, Catton M, Ghilardi JR, Levin LA, Maggio JE, Mantyh PW. Expression of endothelin-B receptors by glia in vivo is increased after CNS injury in rats, rabbits, and humans. Experimental Neurology. 145: 180-95. PMID 9184120 DOI: 10.1006/exnr.1997.6468  1
1997 Liu H, Mantyh PW, Basbaum AI. NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature. 386: 721-4. PMID 9109489 DOI: 10.1038/386721a0  1
1997 Esler WP, Stimson ER, Ghilardi JR, Felix AM, Lu YA, Vinters HV, Mantyh PW, Maggio JE. A beta deposition inhibitor screen using synthetic amyloid. Nature Biotechnology. 15: 258-63. PMID 9062926 DOI: 10.1038/nbt0397-258  1
1996 Ghilardi JR, Catton M, Stimson ER, Rogers S, Walker LC, Maggio JE, Mantyh PW. Intra-arterial infusion of [125I]A beta 1-40 labels amyloid deposits in the aged primate brain in vivo. Neuroreport. 7: 2607-11. PMID 8981432  1
1996 Esler WP, Stimson ER, Ghilardi JR, Lu YA, Felix AM, Vinters HV, Mantyh PW, Lee JP, Maggio JE. Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence. Biochemistry. 35: 13914-21. PMID 8909288 DOI: 10.1021/bi961302+  1
1996 Mantyh CR, Pappas TN, Lapp JA, Washington MK, Neville LM, Ghilardi JR, Rogers SD, Mantyh PW, Vigna SR. Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum. Gastroenterology. 111: 1272-80. PMID 8898641 DOI: 10.1053/gast.1996.v111.pm8898641  1
1996 Abbadie C, Brown JL, Mantyh PW, Basbaum AI. Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience. 70: 201-9. PMID 8848125  1
1996 Mantyh PW, Rogers SD, Ghilardi JR, Maggio JE, Mantyh CR, Vigna SR. Differential expression of two isoforms of the neurokinin-1 (substance P) receptor in vivo. Brain Research. 719: 8-13. PMID 8782857 DOI: 10.1016/0006-8993(96)00050-9  1
1996 Maggio JE, Mantyh PW. Brain amyloid - A physicochemical perspective Brain Pathology. 6: 147-162. PMID 8737930  1
1996 Hodges-Savola C, Rogers SD, Ghilardi JR, Timm DR, Mantyh PW. Beta-adrenergic receptors regulate astrogliosis and cell proliferation in the central nervous system in vivo. Glia. 17: 52-62. PMID 8723842 DOI: 10.1002/(SICI)1098-1136(199605)17:1<52::AID-GLIA5>3.0.CO;2-9  1
1996 Mantyh CR, Maggio JE, Mantyh PW, Vigna SR, Pappas TN. Increased substance P receptor expression by blood vessels and lymphoid aggregates in Clostridium difficile-induced pseudomembranous colitis Digestive Diseases and Sciences. 41: 614-620. PMID 8617145 DOI: 10.1007/BF02282350  1
1996 Esler WP, Stimson ER, Jennings JM, Ghilardi JR, Mantyh PW, Maggio JE. Zinc-induced aggregation of human and rat β-amyloid peptides in vitro Journal of Neurochemistry. 66: 723-732. PMID 8592145  1
1996 Esler WP, Stimson ER, Ghilardi JR, Vinters HV, Lee JP, Mantyh PW, Maggio JE. In vitro growth of Alzheimer's disease β-amyloid plaques displays first-order kinetics Biochemistry. 35: 749-757. PMID 8547255  1
1995 Takatsuji K, Senba E, Mantyh PW, Tohyama M. A relationship between substance P receptor and retinal fibers in the rat suprachiasmatic nucleus Brain Research. 698: 53-61. PMID 8581503 DOI: 10.1016/0006-8993(95)00802-W  1
1995 Mantyh PW, Rogers SD, Allen CJ, Catton MD, Ghilardi JR, Levin LA, Maggio JE, Vigna SR. Beta 2-adrenergic receptors are expressed by glia in vivo in the normal and injured central nervous system in the rat, rabbit, and human. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 152-64. PMID 7823126  1
1995 Mantyh CR, Vigna SR, Bollinger RR, Mantyh PW, Maggio JE, Pappas TN. Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis Gastroenterology. 109: 850-860. PMID 7657114 DOI: 10.1016/0016-5085(95)90394-1  1
1995 Brown JL, Liu H, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI. Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. The Journal of Comparative Neurology. 356: 327-44. PMID 7642798 DOI: 10.1002/cne.903560302  1
1995 Fitzgerald DJ, Maggio JE, Esler WP, Stimson ER, Jennings JM, Ghilardi JR, Mantyh PW. Zinc and Alzheimer's disease Science. 268: 1920-1921. PMID 7604268  1
1995 Mantyh PW, DeMaster E, Malhotra A, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, Maggio JE. Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation. Science (New York, N.Y.). 268: 1629-32. PMID 7539937  1
1995 Mantyh PW, Allen CJ, Ghilardi JR, Rogers SD, Mantyh CR, Liu H, Basbaum AI, Vigna SR, Maggio JE. Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo. Proceedings of the National Academy of Sciences of the United States of America. 92: 2622-6. PMID 7535928 DOI: 10.1073/pnas.92.7.2622  1
1994 Mantyh PW, Allen CJ, Rogers S, DeMaster E, Ghilardi JR, Mosconi T, Kruger L, Mannon PJ, Taylor IL, Vigna SR. Some sensory neurons express neuropeptide Y receptors: potential paracrine inhibition of primary afferent nociceptors following peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 3958-68. PMID 8207499  1
1994 Ghilardi JR, Allen CJ, Vigna SR, McVey DC, Mantyh PW. Cholecystokinin and neuropeptide Y receptors on single rabbit vagal afferent ganglion neurons: site of prejunctional modulation of visceral sensory neurons. Brain Research. 633: 33-40. PMID 8137166 DOI: 10.1016/0006-8993(94)91519-9  1
1994 Mantyh CR, Vigna SR, Maggio JE, Mantyh PW, Bollinger RR, Pappas TN. Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors Neuroscience Letters. 178: 255-259. PMID 7529913 DOI: 10.1016/0304-3940(94)90772-2  1
1994 Liu H, Brown JL, Jasmin L, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI. Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proceedings of the National Academy of Sciences of the United States of America. 91: 1009-13. PMID 7508118  1
1993 Kilgore WR, Mantyh PW, Mantyh CR, McVey DC, Vigna SR. Bombesin/GRP-preferring and neuromedin B-preferring receptors in the rat urogenital system Neuropeptides. 24: 43-52. PMID 8381528 DOI: 10.1016/0143-4179(93)90039-D  1
1993 Mantyh PW, Ghilardi JR, Rogers S, DeMaster E, Allen CJ, Stimson ER, Maggio JE. Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide. Journal of Neurochemistry. 61: 1171-4. PMID 8360682  1
1993 Allen CJ, Ghilardi JR, Vigna SR, Mannon PJ, Taylor IL, McVey DC, Maggio JE, Mantyh PW. Neuropeptide Y/peptide YY receptor binding sites in the heart: localization and pharmacological characterization. Neuroscience. 53: 889-98. PMID 7683778 DOI: 10.1016/0306-4522(93)90633-Q  1
1992 Maggio JE, Stimson ER, Ghilardi JR, Allen CJ, Dahl CE, Whitcomb DC, Vigna SR, Vinters HV, Labenski ME, Mantyh PW. Reversible in vitro growth of Alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide. Proceedings of the National Academy of Sciences of the United States of America. 89: 5462-6. PMID 1608956  1
1992 Ghilardi JR, Allen CJ, Vigna SR, McVey DC, Mantyh PW. Trigeminal and dorsal root ganglion neurons express CCK receptor binding sites in the rat, rabbit, and monkey: possible site of opiate-CCK analgesic interactions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 4854-66. PMID 1334505  1
1992 Mantyh PW, Catton MD, Allen CJ, Labenski ME, Maggio JE, Vigna SR. Receptor binding sites for cholecystokinin, galanin, somatostatin, substance P and vasoactive intestinal polypeptide in sympathetic ganglia. Neuroscience. 46: 739-54. PMID 1312231 DOI: 10.1016/0306-4522(92)90160-4  1
1991 MANTYH PW. Substance P and the Inflammatory and Immune Response Annals of the New York Academy of Sciences. 632: 263-271. PMID 1719871 DOI: 10.1111/j.1749-6632.1991.tb33114.x  1
1991 Mantyh PW, Catton M, Maggio JE, Vigna SR. Alterations in receptors for sensory neuropeptides in human inflammatory bowel disease Advances in Experimental Medicine and Biology. 298: 253-283. PMID 1659149  1
1990 Vigna SR, Giraud AS, Mantyh PW, Soll AH, Walsh JH. Characterization of bombesin receptors on canine antral gastrin cells Peptides. 11: 259-264. PMID 1972573 DOI: 10.1016/0196-9781(90)90079-K  1
1990 Helke CJ, Krause JE, Mantyh PW, Couture R, Bannon MJ. Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 1606-15. PMID 1969374  1
1989 Vigna SR, Giraud AS, Soll AH, Walsh JH, Mantyh PW. Bombesin receptors on gastrin cells Annals of the New York Academy of Sciences. 547: 131-137. PMID 2853590  1
1989 Kruger L, Silverman JD, Mantyh PW, Sternini C, Brecha NC. Peripheral patterns of calcitonin-gene-related peptide general somatic sensory innervation: cutaneous and deep terminations. The Journal of Comparative Neurology. 280: 291-302. PMID 2784448 DOI: 10.1002/cne.902800210  1
1989 Zimmerman RP, Gates TS, Mantyh CR, Vigna SR, Welton ML, Passaro EP, Mantyh PW. Vasoactive intestinal polypeptide receptor binding sites in the human gastrointestinal tract: localization by autoradiography. Neuroscience. 31: 771-83. PMID 2556662 DOI: 10.1016/0306-4522(89)90440-5  1
1989 Gates TS, Zimmerman RP, Mantyh CR, Vigna SR, Mantyh PW. Calcitonin gene-related peptide-alpha receptor binding sites in the gastrointestinal tract. Neuroscience. 31: 757-70. PMID 2556661 DOI: 10.1016/0306-4522(89)90439-9  1
1989 Bacay AC, Mantyh CR, Cohen AH, Mantyh PW, Fine LG. Glomerular atrial natriuretic factor receptors in primary glomerulopathies: studies on human renal biopsies. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 14: 386-95. PMID 2554728  1
1989 Mantyh PW, Catton MD, Boehmer CG, Welton ML, Passaro EP, Maggio JE, Vigna SR. Receptors for sensory neuropeptides in human inflammatory diseases: implications for the effector role of sensory neurons. Peptides. 10: 627-45. PMID 2550912 DOI: 10.1016/0196-9781(89)90154-X  1
1989 Mantyh PW, Gates T, Mantyh CR, Maggio JE. Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues Journal of Neuroscience. 9: 258-279. PMID 2536418  1
1989 Boehmer CG, Norman J, Catton M, Fine LG, Mantyh PW. High levels of mRNA coding for substance P, somatostatin and α-tubulin are expressed by rat and rabbit dorsal root ganglia neurons Peptides. 10: 1179-1194. PMID 2482965 DOI: 10.1016/0196-9781(89)90011-9  1
1989 Vigna SR, Mantyh CR, Soll AH, Maggio JE, Mantyh PW. Substance P receptors on canine chief cells: Localization, characterization, and function Journal of Neuroscience. 9: 2878-2886. PMID 2475593  1
1989 Mantyh PW, Johnson DJ, Boehmer CG, Catton MD, Vinters HV, Maggio JE, Too HP, Vigna SR. Substance P receptor binding sites are expressed by glia in vivo after neuronal injury Proceedings of the National Academy of Sciences of the United States of America. 86: 5193-5197. PMID 2472640  1
1989 Welton ML, Mantyh CR, Gates TS, Popper P, Vigna SR, Maggio JE, Passaro E, Mantyh PW. Localization of bombesin receptors in the human gastrointestinal tract using quantitative receptor autoradiography Annals of the New York Academy of Sciences. 547: 468-470.  1
1988 Zimmerman RP, Gates TS, Boehmer CG, Mantyh PW. Epidermal growth factor receptors in the human colon. European Journal of Pharmacology. 150: 201-2. PMID 3402539 DOI: 10.1016/0014-2999(88)90771-6  1
1988 Zimmerman RP, Gates TS, Boehmer CG, Mantyh PW. Epidermal growth factor receptors in the canine antrum. Peptides. 9: 1411-4. PMID 3266792 DOI: 10.1016/0196-9781(88)90211-2  1
1988 Kruger L, Sternini C, Brecha NC, Mantyh PW. Distribution of calcitonin gene-related peptide immunoreactivity in relation to the rat central somatosensory projection. The Journal of Comparative Neurology. 273: 149-62. PMID 3047185 DOI: 10.1002/cne.902730203  1
1988 Zimmerman RP, Gates TS, Mantyh CR, Vigna SR, Boehmer CG, Mantyh PW. Vasoactive intestinal peptide (VIP) receptors in the canine gastrointestinal tract. Peptides. 9: 1241-53. PMID 2854625 DOI: 10.1016/0196-9781(88)90188-X  1
1988 Bacay AC, Mantyh CR, Vigna SR, Mantyh PW. Receptor binding sites for atrial natriuretic factor are expressed by brown adipose tissue Peptides. 9: 1021-1026. PMID 2854242 DOI: 10.1016/0196-9781(88)90083-6  1
1988 Kruger L, Mantyh PW, Sternini C, Brecha NC, Mantyh CR. Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites. Brain Research. 463: 223-44. PMID 2848610 DOI: 10.1016/0006-8993(88)90395-2  1
1988 Mantyh CR, Gates TS, Zimmerman RP, Welton ML, Passaro EP, Vigna SR, Maggio JE, Kruger L, Mantyh PW. Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease. Proceedings of the National Academy of Sciences of the United States of America. 85: 3235-9. PMID 2834738  1
1988 Gates TS, Zimmerman RP, Mantyh CR, Vigna SR, Maggio JE, Welton ML, Passaro EP, Mantyh PW. Substance P and substance K receptor binding sites in the human gastrointestinal tract: localization by autoradiography. Peptides. 9: 1207-19. PMID 2470062 DOI: 10.1016/0196-9781(88)90184-2  1
1988 Mantyh PW, Mantyh CR, Gates T, Vigna SR, Maggio JE. Receptor binding sites for substance P and substance K in the canine gastrointestinal tract and their possible role in inflammatory bowel disease Neuroscience. 25: 817-837. PMID 2457186 DOI: 10.1016/0306-4522(88)90038-3  1
1988 Popper P, Mantyh CR, Vigna SR, Maggio JE, Mantyh PW. The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes Peptides. 9: 257-267. PMID 2453853 DOI: 10.1016/0196-9781(88)90258-6  1
1987 Vigna SR, Mantyh CR, Giraud AS, Soll AH, Walsh JH, Mantyh PW. Localization of specific binding sites for bombesin in the canine gastrointestinal tract Gastroenterology. 93: 1287-1295. PMID 3678747  1
1987 Akesson TR, Mantyh PW, Mantyh CR, Matt DW, Micevych PE. Estrous cyclicity of 125I-cholecystokinin octapeptide binding in the ventromedial hypothalamic nucleus. Evidence for downmodulation by estrogen. Neuroendocrinology. 45: 257-62. PMID 3574604  1
1987 Mantyh CR, Kruger L, Brecha NC, Mantyh PW. Localization of specific binding sites for atrial natriuretic factor in the central nervous system of rat, guinea pig, cat and human. Brain Research. 412: 329-42. PMID 2955851 DOI: 10.1016/0006-8993(87)91140-1  1
1986 Mantyh CR, Kruger L, Brecha NC, Mantyh PW. Localization of specific binding sites for atrial natriuretic factor in peripheral tissues of the guinea pig, rat, and human. Hypertension. 8: 712-21. PMID 2942474  1
1986 Mantyh PW, Hunt SP. Changes in 3H-substance P receptor binding in the rat brain after kainic acid lesion of the corpus striatum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1537-44. PMID 2423660  1
1985 Mantyh CR, Brecha NC, Soon-Shiong P, Mantyh PW. Specific binding sites for atrial natriuretic factor in the human kidney. The New England Journal of Medicine. 312: 1710. PMID 3158816 DOI: 10.1056/NEJM198506273122617  1
1985 Goedert M, Lightman SL, Mantyh PW, Hunt SP, Emson PC. Neurotensin-like immunoreactivity and neurotensin receptors in the rat hypothalamus and in the neurointermediate lobe of the pituitary gland. Brain Research. 358: 59-69. PMID 3000519 DOI: 10.1016/0006-8993(85)90948-5  1
1985 Mantyh CR, Mantyh PW. Differential localization of cholecystokinin-8 binding sites in the rat vs. the guinea pig brain European Journal of Pharmacology. 113: 137-139. PMID 2995055 DOI: 10.1016/0014-2999(85)90356-5  1
1985 Goedert M, Hunt SP, Mantyh PW, Emson PC. The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum. Brain Research. 352: 127-31. PMID 2988709 DOI: 10.1016/0165-3806(85)90095-1  1
1985 Mantyh PW, Hunt SP. The autoradiographic localization of substance P receptors in the rat and bovine spinal cord and the rat and cat spinal trigeminal nucleus pars caudalis and the effects of neonatal capsaicin. Brain Research. 332: 315-24. PMID 2986763 DOI: 10.1016/0006-8993(85)90600-6  1
1985 Mantyh PW, Hunt SP. Thyrotropin-releasing hormone (TRH) receptors. Localization by light microscopic autoradiography in rat brain using [3H][3-Me-His2]TRH as the radioligand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 551-61. PMID 2983042  1
1985 Kalivas PW, Deutch AY, Maggio JE, Mantyh PW, Roth RH. Substance K and substance P in the ventral tegmental area. Neuroscience Letters. 57: 241-6. PMID 2412193 DOI: 10.1016/0304-3940(85)90498-7  1
1984 Goedert M, Mantyh PW, Emson PC, Hunt SP. Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum. Nature. 307: 543-6. PMID 6320012 DOI: 10.1038/307543a0  1
1984 Mantyh PW, Pinnock RD, Downes CP, Goedert M, Hunt SP. Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS. Nature. 309: 795-7. PMID 6204206 DOI: 10.1038/309795a0  1
1984 Goedert M, Pinnock RD, Downes CP, Mantyh PW, Emson PC. Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices. Brain Research. 323: 193-7. PMID 6098333 DOI: 10.1016/0006-8993(84)90288-9  1
1984 Mantyh PW, Hunt SP, Maggio JE. Substance P receptors: localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand. Brain Research. 307: 147-65. PMID 6087984 DOI: 10.1016/0006-8993(84)90470-0  1
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