Donald P. Knowles - Publications

Affiliations: 
Washington State University, Pullman, WA, United States 
Area:
Veterinary Science Biology, Microbiology Biology, Entomology Biology

190 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sears KP, Knowles DP, Fry LM. Clinical Progression of in Splenectomized Horses Reveals Decreased Virulence Compared to . Pathogens (Basel, Switzerland). 11. PMID 35215197 DOI: 10.3390/pathogens11020254  0.332
2021 Vimonish R, Dinkel KD, Fry LM, Johnson WC, Capelli-Peixoto J, Bastos RG, Scoles GA, Knowles DP, Madder M, Chaka G, Ueti MW. Isolation of infectious Theileria parva sporozoites secreted by infected Rhipicephalus appendiculatus ticks into an in vitro tick feeding system. Parasites & Vectors. 14: 616. PMID 34952641 DOI: 10.1186/s13071-021-05120-7  0.635
2021 Bastos RG, Sears KP, Dinkel KD, Kappmeyer L, Ueti MW, Knowles DP, Fry LM. Development of an Indirect ELISA to Detect Equine Antibodies to . Pathogens (Basel, Switzerland). 10. PMID 33673478 DOI: 10.3390/pathogens10030270  0.644
2020 Sears K, Knowles D, Dinkel K, Mshelia PW, Onzere C, Silva M, Fry L. Imidocarb Dipropionate Lacks Efficacy against and Fails to Consistently Clear in Horses Co-Infected with . Pathogens (Basel, Switzerland). 9. PMID 33321715 DOI: 10.3390/pathogens9121035  0.312
2020 Mahmoud MS, Kandil OM, Abu El-Ezz NT, Hendawy SHM, Elsawy BSM, Knowles DP, Bastos RG, Kappmeyer LS, Laughery JM, Alzan HF, Suarez CE. Identification and antigenicity of the Babesia caballi spherical body protein 4 (SBP4). Parasites & Vectors. 13: 369. PMID 32698835 DOI: 10.1186/S13071-020-04241-9  0.402
2020 Bishop RP, Kappmeyer LS, Onzere CK, Odongo DO, Githaka N, Sears KP, Knowles DP, Fry LM. Equid infective Theileria cluster in distinct 18S rRNA gene clades comprising multiple taxa with unusually broad mammalian host ranges. Parasites & Vectors. 13: 261. PMID 32430015 DOI: 10.1186/S13071-020-04131-0  0.41
2020 Bishop RP, Odongo D, Ahmed J, Mwamuye M, Fry LM, Knowles DP, Nanteza A, Lubega G, Gwakisa P, Clausen PH, Obara I. A review of recent research on Theileria parva: Implications for the infection and treatment vaccination method for control of East Coast fever. Transboundary and Emerging Diseases. 67: 56-67. PMID 32174044 DOI: 10.1111/Tbed.13325  0.403
2020 Tretina K, Haidar M, Madsen-Bouterse SA, Sakura T, Mfarrej S, Fry L, Chaussepied M, Pain A, Knowles DP, Nene VM, Ginsberg D, Daubenberger CA, Bishop RP, Langsley G, Silva JC. Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation. Scientific Reports. 10: 3982. PMID 32132598 DOI: 10.1038/S41598-020-60939-X  0.357
2019 Silva MG, Madsen-Bouterse SA, Dassanayake RP, Mousel M, Knowles DP. Tissue inhibitor of metalloproteinase-1 and interleukin-10 in serum from naïve and scrapie infected sheep. Veterinary and Animal Science. 7: 100056. PMID 32734077 DOI: 10.1016/J.Vas.2019.100056  0.365
2019 Bastos RG, Sears K, Dinkel KD, Knowles DP, Fry LM. Changes in the molecular and functional phenotype of bovine monocytes during infection. Infection and Immunity. PMID 31570561 DOI: 10.1128/Iai.00703-19  0.455
2019 Urie NJ, Highland MA, Knowles DP, Branan MA, Herndon DR, Marshall KL. Mycoplasma ovis infection in domestic sheep (Ovis aries) in the United States: Prevalence, distribution, associated risk factors, and associated outcomes. Preventive Veterinary Medicine. 171: 104750. PMID 31472359 DOI: 10.1016/J.Prevetmed.2019.104750  0.343
2019 Sears KP, Kappmeyer LS, Wise LN, Silva M, Ueti MW, White S, Reif KE, Knowles DP. Infection dynamics of Theileria equi and Theileria haneyi, a newly discovered apicomplexan of the horse. Veterinary Parasitology. 271: 68-75. PMID 31303207 DOI: 10.1016/J.Vetpar.2019.06.009  0.64
2019 Bastos RG, Franceschi V, Tebaldi G, Connelley T, Morrison WI, Knowles DP, Donofrio G, Fry LM. Molecular and Antigenic Properties of Mammalian Cell-Expressed Antigen Tp9. Frontiers in Immunology. 10: 897. PMID 31110506 DOI: 10.3389/Fimmu.2019.00897  0.351
2019 Williams LBA, Fry LM, Herndon DR, Franceschi V, Schneider DA, Donofrio G, Knowles DP. A recombinant bovine herpesvirus-4 vectored vaccine delivered via intranasal nebulization elicits viral neutralizing antibody titers in cattle. Plos One. 14: e0215605. PMID 31002724 DOI: 10.1371/Journal.Pone.0215605  0.385
2019 Fry LM, Bastos RG, Stone BC, Williams LB, Knowles DP, Murphy SC. Gene gun DNA immunization of cattle induces humoral and CD4 T-cell-mediated immune responses against the Theileria parva polymorphic immunodominant molecule. Vaccine. PMID 30782490 DOI: 10.1016/J.Vaccine.2019.02.009  0.33
2018 Wise LN, Kappmeyer LS, Knowles DP, White SN. Evolution and diversity of the EMA families of the divergent equid parasites, Theileria equi and T. haneyi. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 68: 153-160. PMID 30576837 DOI: 10.1016/J.Meegid.2018.12.020  0.392
2018 Alhajri SM, Cunha CW, Knowles DP, Li H, Taus NS. Evaluation of glycoprotein Ov8 as a potential antigen for an OvHV-2-specific diagnostic assay. Plos One. 13: e0200130. PMID 29966004 DOI: 10.1371/Journal.Pone.0200130  0.416
2018 Knowles DP, Kappmeyer LS, Haney D, Herndon DR, Fry LM, Munro JB, Sears K, Ueti MW, Wise LN, Silva M, Schneider DA, Grause J, White SN, Tretina K, Bishop RP, et al. Discovery of a novel species, Theileria haneyi n. sp., infective to equids, highlights exceptional genomic diversity within the genus Theileria: implications for apicomplexan parasite surveillance. International Journal For Parasitology. PMID 29885436 DOI: 10.1016/J.Ijpara.2018.03.010  0.66
2018 Silva MG, Villarino NF, Knowles DP, Suarez CE. Assessment of Draxxin (tulathromycin) as an inhibitor of in vitro growth of Babesia bovis, Babesia bigemina and Theileria equi. International Journal For Parasitology. Drugs and Drug Resistance. 8: 265-270. PMID 29689532 DOI: 10.1016/J.Ijpddr.2018.04.004  0.381
2018 Silva MG, Knowles DP, Mazuz ML, Cooke BM, Suarez CE. Stable transformation of Babesia bigemina and Babesia bovis using a single transfection plasmid. Scientific Reports. 8: 6096. PMID 29666434 DOI: 10.1038/S41598-018-23010-4  0.335
2017 Oliveira RD, Mousel MR, Pabilonia KL, Highland MA, Taylor JB, Knowles DP, White SN. Domestic sheep show average Coxiella burnetii seropositivity generations after a sheep-associated human Q fever outbreak and lack detectable shedding by placental, vaginal, and fecal routes. Plos One. 12: e0188054. PMID 29141023 DOI: 10.1371/Journal.Pone.0188054  0.333
2017 Wise LN, Kappmeyer LS, Silva MG, White SN, Grause JF, Knowles DP. Verification of post-chemotherapeutic clearance of Theileria equi through concordance of nested PCR and immunoblot. Ticks and Tick-Borne Diseases. PMID 28887100 DOI: 10.1016/J.Ttbdis.2017.08.007  0.442
2017 G Silva M, Knowles DP, Antunes S, Domingos A, Esteves MA, Suarez CE. Inhibition of the in vitro growth of Babesia bigemina, Babesia caballi and Theileria equi parasites by trifluralin analogues. Ticks and Tick-Borne Diseases. PMID 28416183 DOI: 10.1016/J.Ttbdis.2017.04.002  0.365
2016 Oldiges DP, Laughery JM, Tagliari NJ, Leite Filho RV, Davis WC, da Silva Vaz I, Termignoni C, Knowles DP, Suarez CE. Transfected Babesia bovis Expressing a Tick GST as a Live Vector Vaccine. Plos Neglected Tropical Diseases. 10: e0005152. PMID 27911903 DOI: 10.1371/Journal.Pntd.0005152  0.4
2016 Alzan HF, Knowles DP, Suarez CE. Comparative Bioinformatics Analysis of Transcription Factor Genes Indicates Conservation of Key Regulatory Domains among Babesia bovis, Babesia microti, and Theileria equi. Plos Neglected Tropical Diseases. 10: e0004983. PMID 27832060 DOI: 10.1371/Journal.Pntd.0004983  0.358
2016 Alzan HF, Lau AO, Knowles DP, Herndon DR, Ueti MW, Scoles GA, Kappmeyer LS, Suarez CE. Expression of 6-Cys Gene Superfamily Defines Babesia bovis Sexual Stage Development within Rhipicephalus microplus. Plos One. 11: e0163791. PMID 27668751 DOI: 10.1371/Journal.Pone.0163791  0.64
2016 Highland MA, Schneider DA, White SN, Madsen-Bouterse SA, Knowles DP, Davis WC. Differences in leukocyte differentiation molecule abundances on domestic sheep (Ovis aries) and bighorn sheep (Ovis canadensis) neutrophils identified by flow cytometry. Comparative Immunology, Microbiology and Infectious Diseases. 46: 40-6. PMID 27260809 DOI: 10.1016/J.Cimid.2016.04.006  0.311
2016 Fry LM, Schneider DA, Frevert CW, Nelson DD, Morrison WI, Knowles DP. East Coast Fever Caused by Theileria parva Is Characterized by Macrophage Activation Associated with Vasculitis and Respiratory Failure. Plos One. 11: e0156004. PMID 27195791 DOI: 10.1371/Journal.Pone.0156004  0.354
2016 Gotia HT, Munro JB, Knowles DP, Daubenberger CA, Bishop RP, Silva JC. Absolute Quantification of the Host-To-Parasite DNA Ratio in Theileria parva-Infected Lymphocyte Cell Lines. Plos One. 11: e0150401. PMID 26930209 DOI: 10.1371/Journal.Pone.0150401  0.439
2015 Mousel MR, White SN, Herndon DR, Reynolds JO, Gonzalez MV, Johnson WC, Ueti MW, Taylor JB, Knowles DP. Ovine leukocyte profiles do not associate with variation in the prion gene, but are breed dependent. Animal Genetics. PMID 26685793 DOI: 10.1111/Age.12381  0.584
2015 Dassanayake RP, Orru CD, Hughson AG, Caughey B, Graça T, Zhuang D, Madsen-Bouterse SA, Knowles DP, Schneider DA. Sensitive and Specific Detection of Classical Scrapie Prions in the Brains of Goats by Real-Time Quaking-Induced Conversion. The Journal of General Virology. PMID 26653410 DOI: 10.1099/Jgv.0.000367  0.305
2015 Hines SA, Ramsay JD, Kappmeyer LS, Lau AO, Ojo KK, Van Voorhis WC, Knowles DP, Mealey RH. Theileria equi isolates vary in susceptibility to imidocarb dipropionate but demonstrate uniform in vitro susceptibility to a bumped kinase inhibitor. Parasites & Vectors. 8: 33. PMID 25600252 DOI: 10.1186/S13071-014-0611-6  0.387
2015 Ramsay JD, Evanoff R, Wilkinson TE, Divers TJ, Knowles DP, Mealey RH. Experimental transmission of equine hepacivirus in horses as a model for hepatitis C virus. Hepatology (Baltimore, Md.). 61: 1533-46. PMID 25580897 DOI: 10.1002/Hep.27689  0.332
2015 Cunha CW, Knowles DP, Taus NS, O'Toole D, Nicola AV, Aguilar HC, Li H. Antibodies to ovine herpesvirus 2 glycoproteins decrease virus infectivity and prevent malignant catarrhal fever in rabbits. Veterinary Microbiology. 175: 349-55. PMID 25542288 DOI: 10.1016/J.Vetmic.2014.11.026  0.422
2014 Li H, Cunha CW, Taus NS, Knowles DP. Malignant catarrhal fever: inching toward understanding. Annual Review of Animal Biosciences. 2: 209-33. PMID 25384141 DOI: 10.1146/Annurev-Animal-022513-114156  0.355
2014 Laughery JM, Knowles DP, Schneider DA, Bastos RG, McElwain TF, Suarez CE. Targeted surface expression of an exogenous antigen in stably transfected Babesia bovis. Plos One. 9: e97890. PMID 24840336 DOI: 10.1371/Journal.Pone.0097890  0.348
2014 White SN, Mousel MR, Gonzalez MV, Highland MA, Herrmann-Hoesing LM, Taylor JB, Knowles DP. Association analysis of variant near ZNF389 with ewe cumulative production in three sheep breeds. Animal Genetics. 45: 613-4. PMID 24720487 DOI: 10.1111/Age.12161  0.316
2014 Chung C, Wilson C, Bandaranayaka-Mudiyanselage CB, Kang E, Adams DS, Kappmeyer LS, Knowles DP, McElwain TF, Evermann JF, Ueti MW, Scoles GA, Lee SS, McGuire TC. Improved diagnostic performance of a commercial Anaplasma antibody competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5-glutathione S-transferase fusion protein as antigen. Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 26: 61-71. PMID 24318928 DOI: 10.1177/1040638713511813  0.595
2014 White SN, Mousel MR, Reynolds JO, Herrmann-Hoesing LM, Knowles DP. Deletion variant near ZNF389 is associated with control of ovine lentivirus in multiple sheep flocks. Animal Genetics. 45: 297-300. PMID 24303974 DOI: 10.1111/Age.12107  0.416
2013 Ramsay JD, Ueti MW, Johnson WC, Scoles GA, Knowles DP, Mealey RH. Lymphocytes and macrophages are infected by Theileria equi, but T cells and B cells are not required to establish infection in vivo. Plos One. 8: e76996. PMID 24116194 DOI: 10.1371/Journal.Pone.0076996  0.701
2013 Awinda PO, Mealey RH, Williams LB, Conrad PA, Packham AE, Reif KE, Grause JF, Pelzel-McCluskey AM, Chung C, Bastos RG, Kappmeyer LS, Howe DK, Ness SL, Knowles DP, Ueti MW. Serum antibodies from a subset of horses positive for Babesia caballi by competitive enzyme-linked immunosorbent assay demonstrate a protein recognition pattern that is not consistent with infection. Clinical and Vaccine Immunology : Cvi. 20: 1752-7. PMID 24049108 DOI: 10.1128/Cvi.00479-13  0.678
2013 Wise LN, Kappmeyer LS, Mealey RH, Knowles DP. Review of equine piroplasmosis. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 27: 1334-46. PMID 24033559 DOI: 10.1111/Jvim.12168  0.46
2013 Bastos RG, Suarez CE, Laughery JM, Johnson WC, Ueti MW, Knowles DP. Differential expression of three members of the multidomain adhesion CCp family in Babesia bigemina, Babesia bovis and Theileria equi. Plos One. 8: e67765. PMID 23844089 DOI: 10.1371/Journal.Pone.0067765  0.644
2013 White SN, Knowles DP. Expanding possibilities for intervention against small ruminant lentiviruses through genetic marker-assisted selective breeding. Viruses. 5: 1466-99. PMID 23771240 DOI: 10.3390/V5061466  0.338
2013 Silva MG, Graça T, Suarez CE, Knowles DP. Repertoire of Theileria equi immunodominant antigens bound by equine antibody. Molecular and Biochemical Parasitology. 188: 109-15. PMID 23541863 DOI: 10.1016/J.Molbiopara.2013.03.002  0.46
2013 Cunha CW, O'Toole D, Taus NS, Knowles DP, Li H. Are rabbits a suitable model to study sheep-associated malignant catarrhal fever in susceptible hosts? Veterinary Microbiology. 163: 358-63. PMID 23394795 DOI: 10.1016/J.Vetmic.2013.01.002  0.434
2013 Li H, Cunha CW, O'Toole D, Nicola AV, Knowles DP, Taus NS. Development of an in vivo system to measure antibody-blocking of ovine herpesvirus 2 entry. Journal of Virological Methods. 188: 104-7. PMID 23274755 DOI: 10.1016/J.Jviromet.2012.12.008  0.393
2013 Grause JF, Ueti MW, Nelson JT, Knowles DP, Kappmeyer LS, Bunn TO. Efficacy of imidocarb dipropionate in eliminating Theileria equi from experimentally infected horses. Veterinary Journal (London, England : 1997). 196: 541-6. PMID 23199699 DOI: 10.1016/J.Tvjl.2012.10.025  0.691
2012 Kappmeyer LS, Thiagarajan M, Herndon DR, Ramsay JD, Caler E, Djikeng A, Gillespie JJ, Lau AO, Roalson EH, Silva JC, Silva MG, Suarez CE, Ueti MW, Nene VM, Mealey RH, ... Knowles DP, et al. Comparative genomic analysis and phylogenetic position of Theileria equi. Bmc Genomics. 13: 603. PMID 23137308 DOI: 10.1186/1471-2164-13-603  0.677
2012 White SN, Mousel MR, Herrmann-Hoesing LM, Reynolds JO, Leymaster KA, Neibergs HL, Lewis GS, Knowles DP. Genome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus. Plos One. 7: e47829. PMID 23082221 DOI: 10.1371/Journal.Pone.0047829  0.426
2012 Ueti MW, Mealey RH, Kappmeyer LS, White SN, Kumpula-McWhirter N, Pelzel AM, Grause JF, Bunn TO, Schwartz A, Traub-Dargatz JL, Hendrickson A, Espy B, Guthrie AJ, Fowler WK, Knowles DP. Re-emergence of the apicomplexan Theileria equi in the United States: elimination of persistent infection and transmission risk. Plos One. 7: e44713. PMID 22970295 DOI: 10.1371/Journal.Pone.0044713  0.702
2012 Cunha CW, Gailbreath KL, O'Toole D, Knowles DP, Schneider DA, White SN, Taus NS, Davies CJ, Davis WC, Li H. Ovine herpesvirus 2 infection in American bison: virus and host dynamics in the development of sheep-associated malignant catarrhal fever. Veterinary Microbiology. 159: 307-19. PMID 22592216 DOI: 10.1016/J.Vetmic.2012.04.021  0.398
2012 Li H, Brooking A, Cunha CW, Highland MA, O'Toole D, Knowles DP, Taus NS. Experimental induction of malignant catarrhal fever in pigs with ovine herpesvirus 2 by intranasal nebulization. Veterinary Microbiology. 159: 485-9. PMID 22560763 DOI: 10.1016/J.Vetmic.2012.04.016  0.412
2012 Short MA, Clark CK, Harvey JW, Wenzlow N, Hawkins IK, Allred DR, Knowles DP, Corn JL, Grause JF, Hennager SG, Kitchen DL, Traub-Dargatz JL. Outbreak of equine piroplasmosis in Florida. Journal of the American Veterinary Medical Association. 240: 588-95. PMID 22332629 DOI: 10.2460/Javma.240.5.588  0.398
2012 Wise LN, Ueti MW, Kappmeyer LS, Hines MT, White SN, Davis W, Knowles DP. In vitro activity of ponazuril against Theileria equi. Veterinary Parasitology. 185: 282-5. PMID 22130334 DOI: 10.1016/J.Vetpar.2011.10.036  0.666
2012 Mealey RH, Kappmeyer LS, Ueti MW, Wagner B, Knowles DP. Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency. Clinical and Vaccine Immunology : Cvi. 19: 100-4. PMID 22038847 DOI: 10.1128/Cvi.05301-11  0.644
2012 Hines S, Kappmeyer L, Mealey K, Leib S, Johnson W, Ueti M, Knowles D, Mealey R. Variation in Theileria equi drug susceptibility in vitro and the potential role of ABC transporters as mediators of parasitic drug resistance Journal of Equine Veterinary Science. 32: S83. DOI: 10.1016/J.Jevs.2012.08.176  0.569
2012 Ramsay J, Ueti M, Johnson W, Scoles G, Knowles D, Mealey R. Macrophages and lymphocytes support the development of Theileria equi pre-erythrocytic stages, but neither B nor T lymphocytes are required to establish infection In vivo Journal of Equine Veterinary Science. 32: S80. DOI: 10.1016/J.Jevs.2012.08.170  0.697
2011 Scoles GA, Hutcheson HJ, Schlater JL, Hennager SG, Pelzel AM, Knowles DP. Equine piroplasmosis associated with Amblyomma cajennense Ticks, Texas, USA. Emerging Infectious Diseases. 17: 1903-5. PMID 22000367 DOI: 10.3201/Eid1710.101182  0.442
2011 Subramaniam R, Shanthalingam S, Bavananthasivam J, Kugadas A, Potter KA, Foreyt WJ, Hodgins DC, Shewen PE, Barrington GM, Knowles DP, Srikumaran S. A multivalent Mannheimia-Bibersteinia vaccine protects bighorn sheep against Mannheimia haemolytica challenge. Clinical and Vaccine Immunology : Cvi. 18: 1689-94. PMID 21832104 DOI: 10.1128/Cvi.05276-11  0.325
2011 Herndon CN, Shanthalingam S, Knowles DP, Call DR, Srikumaran S. Comparison of passively transferred antibodies in bighorn and domestic lambs reveals one factor in differential susceptibility of these species to Mannheimia haemolytica-induced pneumonia. Clinical and Vaccine Immunology : Cvi. 18: 1133-8. PMID 21613459 DOI: 10.1128/Cvi.00044-11  0.355
2011 Li H, Cunha CW, Gailbreath KL, O'Toole D, White SN, Vanderplasschen A, Dewals B, Knowles DP, Taus NS. Characterization of ovine herpesvirus 2-induced malignant catarrhal fever in rabbits. Veterinary Microbiology. 150: 270-7. PMID 21419581 DOI: 10.1016/J.Vetmic.2011.02.016  0.382
2011 Schneider DA, Yan H, Bastos RG, Johnson WC, Gavin PR, Allen AJ, Barrington GM, Herrmann-Hoesing LM, Knowles DP, Goff WL. Dynamics of bovine spleen cell populations during the acute response to Babesia bovis infection: an immunohistological study. Parasite Immunology. 33: 34-44. PMID 21155841 DOI: 10.1111/J.1365-3024.2010.01249.X  0.391
2010 Bastos RG, Ueti MW, Knowles DP, Scoles GA. The Rhipicephalus (Boophilus) microplus Bm86 gene plays a critical role in the fitness of ticks fed on cattle during acute Babesia bovis infection. Parasites & Vectors. 3: 111. PMID 21092112 DOI: 10.1186/1756-3305-3-111  0.652
2010 Lawrence PK, Shanthalingam S, Dassanayake RP, Subramaniam R, Herndon CN, Knowles DP, Rurangirwa FR, Foreyt WJ, Wayman G, Marciel AM, Highlander SK, Srikumaran S. Transmission of Mannheimia haemolytica from domestic sheep (Ovis aries) to bighorn sheep (Ovis canadensis): unequivocal demonstration with green fluorescent protein-tagged organisms. Journal of Wildlife Diseases. 46: 706-17. PMID 20688676 DOI: 10.7589/0090-3558-46.3.706  0.322
2010 Freeman JM, Kappmeyer LS, Ueti MW, McElwain TF, Baszler TV, Echaide I, Nene VM, Knowles DP. A Babesia bovis gene syntenic to Theileria parva p67 is expressed in blood and tick stage parasites. Veterinary Parasitology. 173: 211-8. PMID 20638797 DOI: 10.1016/J.Vetpar.2010.06.024  0.641
2010 Broughton-Neiswanger LE, White SN, Knowles DP, Mousel MR, Lewis GS, Herndon DR, Herrmann-Hoesing LM. Non-maternal transmission is the major mode of ovine lentivirus transmission in a ewe flock: a molecular epidemiology study. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 10: 998-1007. PMID 20601169 DOI: 10.1016/J.Meegid.2010.06.007  0.364
2010 Subramaniam R, Dassanayake RP, Norimine J, Brown WC, Knowles DP, Srikumaran S. Molecular cloning, characterization and in vitro expression of SERPIN B1 of bighorn sheep (Ovis canadensis) and domestic sheep (Ovis aries), and comparison with that of other species. Veterinary Immunology and Immunopathology. 137: 327-31. PMID 20591503 DOI: 10.1016/J.Vetimm.2010.05.017  0.334
2010 Herrmann-Hoesing LM, Noh SM, Snekvik KR, White SN, Schneider DA, Truscott T, Knowles DP. Ovine progressive pneumonia virus capsid antigen as found in CD163- and CD172a-positive alveolar macrophages of persistently infected sheep. Veterinary Pathology. 47: 518-28. PMID 20382821 DOI: 10.1177/0300985809359605  0.339
2010 Taus NS, Schneider DA, Oaks JL, Yan H, Gailbreath KL, Knowles DP, Li H. Sheep (Ovis aries) airway epithelial cells support ovine herpesvirus 2 lytic replication in vivo. Veterinary Microbiology. 145: 47-53. PMID 20381274 DOI: 10.1016/J.Vetmic.2010.03.013  0.424
2010 Gailbreath KL, O'Toole D, Taus NS, Knowles DP, Oaks JL, Li H. Experimental nebulization of American bison (Bison bison) with low doses of ovine herpesvirus 2 from sheep nasal secretions. Veterinary Microbiology. 143: 389-93. PMID 20018461 DOI: 10.1016/J.Vetmic.2009.11.026  0.356
2010 Bastos RG, Ueti MW, Knowles DP, Scoles GA. The Rhipicephalus (Boophilus) microplus Bm86 gene plays a critical role in the fitness of ticks fed on cattle during acute Babesia bovis infection Parasites and Vectors. 3. DOI: 10.1186/1756-3305-3-111  0.618
2010 Howell JM, Ueti MW, Palmer GH, Scoles GA, Knowles DP. Persistently infected calves as reservoirs for acquisition and transovarial transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus (Journal of Clinical Microbiology (2007) 45, 10 (3155-3159)) Journal of Clinical Microbiology. 48: 345. DOI: 10.1128/JCM.02168-09  0.715
2009 Kerber CE, Labruna MB, Ferreira F, De Waal DT, Knowles DP, Gennari SM. Prevalence of equine Piroplasmosis and its association with tick infestation in the State of São Paulo, Brazil. Revista Brasileira De Parasitologia VeterináRia = Brazilian Journal of Veterinary Parasitology : óRgãO Oficial Do ColéGio Brasileiro De Parasitologia VeterináRia. 18: 1-8. PMID 20040201 DOI: 10.4322/Rbpv.01804001  0.337
2009 Bastos RG, Ueti MW, Guerrero FD, Knowles DP, Scoles GA. Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny. Parasites & Vectors. 2: 57. PMID 19930572 DOI: 10.1186/1756-3305-2-57  0.671
2009 Lau AO, McElwain TF, Brayton KA, Knowles DP, Roalson EH. Babesia bovis: a comprehensive phylogenetic analysis of plastid-encoded genes supports green algal origin of apicoplasts. Experimental Parasitology. 123: 236-43. PMID 19646439 DOI: 10.1016/J.Exppara.2009.07.007  0.316
2009 Odongo DO, Ueti MW, Mwaura SN, Knowles DP, Bishop RP, Scoles GA. Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) confirms differences in infection between selected tick strains Journal of Medical Entomology. 46: 888-894. PMID 19645294 DOI: 10.1603/033.046.0422  0.693
2009 Schwint ON, Ueti MW, Palmer GH, Kappmeyer LS, Hines MT, Cordes RT, Knowles DP, Scoles GA. Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential. Antimicrobial Agents and Chemotherapy. 53: 4327-32. PMID 19620328 DOI: 10.1128/Aac.00404-09  0.692
2009 Harrington RD, Herrmann-Hoesing LM, White SN, O'Rourke KI, Knowles DP. Ovine progressive pneumonia provirus levels are unaffected by the prion 171R allele in an Idaho sheep flock. Genetics, Selection, Evolution : Gse. 41: 17. PMID 19284685 DOI: 10.1186/1297-9686-41-17  0.332
2009 Herrmann-Hoesing LM, Noh SM, White SN, Snekvik KR, Truscott T, Knowles DP. Peripheral ovine progressive pneumonia provirus levels correlate with and predict histological tissue lesion severity in naturally infected sheep. Clinical and Vaccine Immunology : Cvi. 16: 551-7. PMID 19261772 DOI: 10.1128/Cvi.00459-08  0.327
2009 Galletti MF, Ueti MW, Knowles DP, Brayton KA, Palmer GH. Independence of Anaplasma marginale strains with high and low transmission efficiencies in the tick vector following simultaneous acquisition by feeding on a superinfected mammalian reservoir host. Infection and Immunity. 77: 1459-64. PMID 19188360 DOI: 10.1128/Iai.01518-08  0.617
2009 Ueti MW, Knowles DP, Davitt CM, Scoles GA, Baszler TV, Palmer GH. Quantitative differences in salivary pathogen load during tick transmission underlie strain-specific variation in transmission efficiency of Anaplasma marginale Infection and Immunity. 77: 70-75. PMID 18955472 DOI: 10.1128/Iai.01164-08  0.641
2009 Bastos RG, Ueti MW, Guerrero FD, Knowles DP, Scoles GA. Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny Parasites and Vectors. 2. DOI: 10.1186/1756-3305-2-57  0.633
2008 Schwint ON, Knowles DP, Ueti MW, Kappmeyer LS, Scoles GA. Transmission of babesia caballi by Dermacentor nitens (Acari: Ixodidae) is restricted to one generation in the absence of alimentary reinfection on a susceptible equine host Journal of Medical Entomology. 45: 1152-1155. PMID 19058641 DOI: 10.1603/0022-2585(2008)45[1152:Tobcbd]2.0.Co;2  0.676
2008 Herrmann-Hoesing LM, White SN, Mousel MR, Lewis GS, Knowles DP. Ovine progressive pneumonia provirus levels associate with breed and Ovar-DRB1. Immunogenetics. 60: 749-58. PMID 18797863 DOI: 10.1007/S00251-008-0328-9  0.315
2008 Stanton JB, Knowles DP, O'Rourke KI, Herrmann-Hoesing LM, Mathison BA, Baszler TV. Small-ruminant lentivirus enhances PrPSc accumulation in cultured sheep microglial cells. Journal of Virology. 82: 9839-47. PMID 18684809 DOI: 10.1128/Jvi.01137-08  0.336
2008 Goff WL, Johnson WC, Molloy JB, Jorgensen WK, Waldron SJ, Figueroa JV, Matthee O, Adams DS, McGuire TC, Pino I, Mosqueda J, Palmer GH, Suarez CE, Knowles DP, McElwain TF. Validation of a competitive enzyme-linked immunosorbent assay for detection of Babesia bigemina antibodies in cattle. Clinical and Vaccine Immunology : Cvi. 15: 1316-21. PMID 18632921 DOI: 10.1128/Cvi.00150-08  0.32
2008 Manning L, O'Rourke KI, Knowles DP, Marsh SA, Spencer YI, Moffat E, Wells GA, Czub S. A collaborative Canadian-United Kingdom evaluation of an immunohistochemistry protocol to diagnose bovine spongiform encephalopathy. Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 20: 504-8. PMID 18599859 DOI: 10.1177/104063870802000416  0.303
2008 Leverich CK, Palmer GH, Knowles DP, Brayton KA. Tick-borne transmission of two genetically distinct Anaplasma marginale strains following superinfection of the mammalian reservoir host. Infection and Immunity. 76: 4066-70. PMID 18573892 DOI: 10.1128/Iai.00594-08  0.323
2008 Li H, Cunha CW, Davies CJ, Gailbreath KL, Knowles DP, Oaks JL, Taus NS. Ovine herpesvirus 2 replicates initially in the lung of experimentally infected sheep. The Journal of General Virology. 89: 1699-708. PMID 18559941 DOI: 10.1099/Vir.0.2008/000554-0  0.396
2008 Gailbreath KL, Taus NS, Cunha CW, Knowles DP, Li H. Experimental infection of rabbits with ovine herpesvirus 2 from sheep nasal secretions. Veterinary Microbiology. 132: 65-73. PMID 18539411 DOI: 10.1016/J.Vetmic.2008.04.035  0.429
2008 Ueti MW, Palmer GH, Scoles GA, Kappmeyer LS, Knowles DP. Persistently infected horses are reservoirs for intrastadial tick-borne transmission of the apicomplexan parasite Babesia equi Infection and Immunity. 76: 3525-3529. PMID 18490466 DOI: 10.1128/Iai.00251-08  0.691
2008 Scoles GA, Goff WL, Lysyk TJ, Lewis GS, Knowles DP. Validation of an Anaplasma marginale cELISA for use in the diagnosis of A. ovis infections in domestic sheep and Anaplasma spp. in wild ungulates Veterinary Microbiology. 130: 184-190. PMID 18272296 DOI: 10.1016/J.Vetmic.2007.12.020  0.432
2008 Futse JE, Brayton KA, Dark MJ, Knowles DP, Palmer GH. Superinfection as a driver of genomic diversification in antigenically variant pathogens. Proceedings of the National Academy of Sciences of the United States of America. 105: 2123-7. PMID 18252822 DOI: 10.1073/Pnas.0710333105  0.365
2008 Besser TE, Cassirer EF, Potter KA, VanderSchalie J, Fischer A, Knowles DP, Herndon DR, Rurangirwa FR, Weiser GC, Srikumaran S. Association of Mycoplasma ovipneumoniae infection with population-limiting respiratory disease in free-ranging Rocky Mountain bighorn sheep (Ovis canadensis canadensis). Journal of Clinical Microbiology. 46: 423-30. PMID 18057131 DOI: 10.1128/Jcm.01931-07  0.32
2007 Brayton KA, Lau AO, Herndon DR, Hannick L, Kappmeyer LS, Berens SJ, Bidwell SL, Brown WC, Crabtree J, Fadrosh D, Feldblum T, Forberger HA, Haas BJ, Howell JM, Khouri H, ... ... Knowles DP, et al. Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa. Plos Pathogens. 3: 1401-13. PMID 17953480 DOI: 10.1371/Journal.Ppat.0030148  0.577
2007 Herrmann-Hoesing LM, White SN, Lewis GS, Mousel MR, Knowles DP. Development and validation of an ovine progressive pneumonia virus quantitative PCR. Clinical and Vaccine Immunology : Cvi. 14: 1274-8. PMID 17699832 DOI: 10.1128/Cvi.00095-07  0.434
2007 Howell JM, Ueti MW, Palmer GH, Scoles GA, Knowles DP. Persistently infected calves as reservoirs for acquisition and transovarial transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus. Journal of Clinical Microbiology. 45: 3155-9. PMID 17687016 DOI: 10.1128/Jcm.00766-07  0.755
2007 Scoles GA, Ueti MW, Noh SM, Knowles DP, Palmer GH. Conservation of transmission phenotype of Anaplasma marginale (Rickettsiales: Anaplasmataceae) strains among Dermacentor and Rhipicephalus ticks (Acari: Ixodidae). Journal of Medical Entomology. 44: 484-91. PMID 17547235 DOI: 10.1093/Jmedent/44.3.484  0.631
2007 Ueti MW, Reagan JO, Knowles DP, Scoles GA, Shkap V, Palmer GH. Identification of midgut and salivary glands as specific and distinct barriers to efficient tick-borne transmission of Anaplasma marginale. Infection and Immunity. 75: 2959-64. PMID 17420231 DOI: 10.1128/Iai.00284-07  0.667
2007 Herrmann-Hoesing LM, Palmer GH, Knowles DP. Evidence of proviral clearance following postpartum transmission of an ovine lentivirus. Virology. 362: 226-34. PMID 17267002 DOI: 10.1016/J.Virol.2006.12.021  0.397
2007 Strik NI, Alleman AR, Barbet AF, Sorenson HL, Wamsley HL, Gaschen FP, Luckschander N, Wong S, Chu F, Foley JE, Bjoersdorff A, Stuen S, Knowles DP. Characterization of Anaplasma phagocytophilum major surface protein 5 and the extent of its cross-reactivity with A. marginale. Clinical and Vaccine Immunology : Cvi. 14: 262-8. PMID 17215333 DOI: 10.1128/Cvi.00320-06  0.422
2007 Palmer GH, Futse JE, Leverich CK, Knowles DP, Rurangirwa FR, Brayton KA. Selection for simple major surface protein 2 variants during Anaplasma marginale transmission to immunologically naïve animals. Infection and Immunity. 75: 1502-6. PMID 17178787 DOI: 10.1128/Iai.01801-06  0.337
2007 Howell JM, Ueti MW, Palmer GH, Scoles GA, Knowles DP. Transovarial transmission efficiency of Babesia bovis tick stages acquired by Rhipicephalus (Boophilus) microplus during acute infection. Journal of Clinical Microbiology. 45: 426-31. PMID 17166964 DOI: 10.1128/Jcm.01757-06  0.753
2006 Palmer GH, Futse JE, Knowles DP, Brayton KA. Insights into mechanisms of bacterial antigenic variation derived from the complete genome sequence of Anaplasma marginale. Annals of the New York Academy of Sciences. 1078: 15-25. PMID 17114676 DOI: 10.1196/Annals.1374.002  0.457
2006 Scoles GA, McElwain TF, Rurangirwa FR, Knowles DP, Lysyk TJ. A Canadian bison isolate of Anaplasma marginale (Rickettsiales: Anaplasmataceae) is not transmissible by Dermacentor andersoni (Acari: Ixodidae), whereas ticks from two Canadian D. andersoni populations are competent vectors of a U.S. strain. Journal of Medical Entomology. 43: 971-5. PMID 17017236 DOI: 10.1603/0022-2585(2006)43[971:Acbioa]2.0.Co;2  0.345
2006 Goff WL, Molloy JB, Johnson WC, Suarez CE, Pino I, Rhalem A, Sahibi H, Ceci L, Carelli G, Adams DS, McGuire TC, Knowles DP, McElwain TF. Validation of a competitive enzyme-linked immunosorbent assay for detection of antibodies against Babesia bovis. Clinical and Vaccine Immunology : Cvi. 13: 1212-6. PMID 16957062 DOI: 10.1128/Cvi.00196-06  0.324
2006 Noh SM, Brayton KA, Knowles DP, Agnes JT, Dark MJ, Brown WC, Baszler TV, Palmer GH. Differential expression and sequence conservation of the Anaplasma marginale msp2 gene superfamily outer membrane proteins. Infection and Immunity. 74: 3471-9. PMID 16714578 DOI: 10.1128/Iai.01843-05  0.433
2006 Brown WC, Norimine J, Knowles DP, Goff WL. Immune control of Babesia bovis infection. Veterinary Parasitology. 138: 75-87. PMID 16510249 DOI: 10.1016/J.Vetpar.2006.01.041  0.444
2006 Norimine J, Ruef BJ, Palmer GH, Knowles DP, Herndon DR, Rice-Ficht AC, Brown WC. A novel 78-kDa fatty acyl-CoA synthetase (ACS1) of Babesia bovis stimulates memory CD4+ T lymphocyte responses in B. bovis-immune cattle. Molecular and Biochemical Parasitology. 147: 20-9. PMID 16469396 DOI: 10.1016/J.Molbiopara.2006.01.004  0.366
2006 Cunha CW, McGuire TC, Kappmeyer LS, Hines SA, Lopez AM, Dellagostin OA, Knowles DP. Development of specific immunoglobulin Ga (IgGa) and IgGb antibodies correlates with control of parasitemia in Babesia equi Infection. Clinical and Vaccine Immunology : Cvi. 13: 297-300. PMID 16467341 DOI: 10.1128/Cvi.13.2.297-300.2006  0.453
2005 Holman PJ, Spencer AM, Telford SR, Goethert HK, Allen AJ, Knowles DP, Goff WL. Comparative infectivity of Babesia divergens and a zoonotic Babesia divergens-like parasite in cattle. The American Journal of Tropical Medicine and Hygiene. 73: 865-70. PMID 16282295 DOI: 10.4269/Ajtmh.2005.73.865  0.442
2005 Li H, Gailbreath K, Flach EJ, Taus NS, Cooley J, Keller J, Russell GC, Knowles DP, Haig DM, Oaks JL, Traul DL, Crawford TB. A novel subgroup of rhadinoviruses in ruminants. The Journal of General Virology. 86: 3021-6. PMID 16227223 DOI: 10.1099/Vir.0.81238-0  0.328
2005 Borucki MK, Gay CC, Reynolds J, McElwain KL, Kim SH, Call DR, Knowles DP. Genetic diversity of Listeria monocytogenes strains from a high-prevalence dairy farm. Applied and Environmental Microbiology. 71: 5893-9. PMID 16204502 DOI: 10.1128/Aem.71.10.5893-5899.2005  0.312
2005 Rodríguez JL, Palmer GH, Knowles DP, Brayton KA. Distinctly different msp2 pseudogene repertoires in Anaplasma marginale strains that are capable of superinfection. Gene. 361: 127-32. PMID 16202540 DOI: 10.1016/J.Gene.2005.06.038  0.357
2005 Ueti MW, Palmer GH, Kappmeyer LS, Statdfield M, Scoles GA, Knowles DP. Ability of the vector tick Boophilus microplus to acquire and transmit Babesia equi following feeding on chronically infected horses with low-level parasitemia. Journal of Clinical Microbiology. 43: 3755-9. PMID 16081906 DOI: 10.1128/Jcm.43.8.3755-3759.2005  0.679
2005 Futse JE, Brayton KA, Knowles DP, Palmer GH. Structural basis for segmental gene conversion in generation of Anaplasma marginale outer membrane protein variants. Molecular Microbiology. 57: 212-21. PMID 15948961 DOI: 10.1111/J.1365-2958.2005.04670.X  0.3
2005 Herrmann LM, McGuire TC, Hötzel I, Lewis GS, Knowles DP. Surface envelope glycoprotein is B-lymphocyte immunodominant in sheep naturally infected with ovine progressive pneumonia virus. Clinical and Diagnostic Laboratory Immunology. 12: 797-800. PMID 15939757 DOI: 10.1128/Cdli.12.6.797-800.2005  0.432
2005 Li H, Keller J, Knowles DP, Taus NS, Oaks JL, Crawford TB. Transmission of caprine herpesvirus 2 in domestic goats. Veterinary Microbiology. 107: 23-9. PMID 15795075 DOI: 10.1016/J.Vetmic.2005.01.014  0.339
2005 Brayton KA, Kappmeyer LS, Herndon DR, Dark MJ, Tibbals DL, Palmer GH, McGuire TC, Knowles DP. Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 102: 844-9. PMID 15618402 DOI: 10.1073/Pnas.0406656102  0.339
2004 Sellon DC, Knowles DP, Greiner EC, Long MT, Hines MT, Hochstatter T, Tibary A, Dame JB. Infection of immunodeficient horses with Sarcocystis neurona does not result in neurologic disease. Clinical and Diagnostic Laboratory Immunology. 11: 1134-9. PMID 15539518 DOI: 10.1128/Cdli.11.6.1134-1139.2004  0.401
2004 Palmer GH, Knowles DP, Rodriguez JL, Gnad DP, Hollis LC, Marston T, Brayton KA. Stochastic transmission of multiple genotypically distinct Anaplasma marginale strains in a herd with high prevalence of Anaplasma infection. Journal of Clinical Microbiology. 42: 5381-4. PMID 15528749 DOI: 10.1128/Jcm.43.7.3587.2005  0.374
2004 Sellon DC, Knowles DP, Greiner EC, Long MT, Hines MT, Hochstatter T, Hasel KM, Ueti M, Gillis K, Dame JB. Depletion of natural killer cells does not result in neurologic disease due to Sarcocystis neurona in mice with severe combined immunodeficiency. The Journal of Parasitology. 90: 782-8. PMID 15357069 DOI: 10.1645/Ge-205R  0.609
2004 O'Rourke KI, Spraker TR, Hamburg LK, Besser TE, Brayton KA, Knowles DP. Polymorphisms in the prion precursor functional gene but not the pseudogene are associated with susceptibility to chronic wasting disease in white-tailed deer. The Journal of General Virology. 85: 1339-46. PMID 15105552 DOI: 10.1099/Vir.0.79785-0  0.301
2004 Brayton KA, O'Rourke KI, Lyda AK, Miller MW, Knowles DP. A processed pseudogene contributes to apparent mule deer prion gene heterogeneity. Gene. 326: 167-73. PMID 14729275 DOI: 10.1016/J.Gene.2003.10.022  0.307
2003 Ueti MW, Palmer GH, Kappmeyer LS, Scoles GA, Knowles DP. Expression of Equi Merozoite Antigen 2 during Development of Babesia equi in the Midgut and Salivary Gland of the Vector Tick Boophilus microplus Journal of Clinical Microbiology. 41: 5803-5809. PMID 14662988 DOI: 10.1128/Jcm.41.12.5803-5809.2003  0.657
2003 Herrmann LM, Cheevers WP, Marshall KL, McGuire TC, Hutton MM, Lewis GS, Knowles DP. Detection of serum antibodies to ovine progressive pneumonia virus in sheep by using a caprine arthritis-encephalitis virus competitive-inhibition enzyme-linked immunosorbent assay. Clinical and Diagnostic Laboratory Immunology. 10: 862-5. PMID 12965917 DOI: 10.1128/Cdli.10.5.862-865.2003  0.333
2003 Goff WL, Johnson WC, Horn RH, Barrington GM, Knowles DP. The innate immune response in calves to Boophilus microplus tick transmitted Babesia bovis involves type-1 cytokine induction and NK-like cells in the spleen. Parasite Immunology. 25: 185-8. PMID 12940961 DOI: 10.1046/J.1365-3024.2003.00625.X  0.318
2003 Futse JE, Ueti MW, Knowles DP, Palmer GH. Transmission of Anaplasma marginale by Boophilus microplus: retention of vector competence in the absence of vector-pathogen interaction. Journal of Clinical Microbiology. 41: 3829-34. PMID 12904396 DOI: 10.1128/Jcm.41.8.3829-3834.2003  0.652
2003 Herrmann LM, Cheevers WP, McGuire TC, Adams DS, Hutton MM, Gavin WG, Knowles DP. Competitive-inhibition enzyme-linked immunosorbent assay for detection of serum antibodies to caprine arthritis-encephalitis virus: diagnostic tool for successful eradication. Clinical and Diagnostic Laboratory Immunology. 10: 267-71. PMID 12626453 DOI: 10.1128/Cdli.10.2.267-271.2003  0.322
2003 Hines SA, Stone DM, Hines MT, Alperin DC, Knowles DP, Norton LK, Hamilton MJ, Davis WC, McGuire TC. Clearance of virulent but not avirulent Rhodococcus equi from the lungs of adult horses is associated with intracytoplasmic gamma interferon production by CD4+ and CD8+ T lymphocytes. Clinical and Diagnostic Laboratory Immunology. 10: 208-15. PMID 12626444 DOI: 10.1128/Cdli.10.2.208-215.2003  0.339
2003 Cheevers WP, Snekvik KR, Trujillo JD, Kumpula-McWhirter NM, Pretty On Top KJ, Knowles DP. Prime-boost vaccination with plasmid DNA encoding caprine-arthritis encephalitis lentivirus env and viral SU suppresses challenge virus and development of arthritis. Virology. 306: 116-25. PMID 12620804 DOI: 10.1016/S0042-6822(02)00044-2  0.304
2003 Goff WL, McElwain TF, Suarez CE, Johnson WC, Brown WC, Norimine J, Knowles DP. Competitive enzyme-linked immunosorbent assay based on a rhoptry-associated protein 1 epitope specifically identifies Babesia bovis-infected cattle. Clinical and Diagnostic Laboratory Immunology. 10: 38-43. PMID 12522037 DOI: 10.1128/Cdli.10.1.38-43.2003  0.447
2002 Cunha CW, Kappmeyer LS, McGuire TC, Dellagostin OA, Knowles DP. Conformational dependence and conservation of an immunodominant epitope within the babesia equi erythrocyte-stage surface protein equi merozoite antigen 1. Clinical and Diagnostic Laboratory Immunology. 9: 1301-6. PMID 12414764 DOI: 10.1128/Cdli.9.6.1301-1306.2002  0.351
2002 Long MT, Mines MT, Knowles DP, Tanhauser SM, Dame JB, Cutler TJ, MacKay RJ, Sellon DC. Sarcocystis neurona: parasitemia in a severe combined immunodeficient (SCID) horse fed sporocysts. Experimental Parasitology. 100: 150-4. PMID 12173399 DOI: 10.1016/S0014-4894(02)00012-7  0.428
2002 Stiller D, Goff WL, Johnson LW, Knowles DP. Dermacentor variabilis and boophilus microplus (Acari: Ixodidae): experimental vectors of Babesia equi to equids. Journal of Medical Entomology. 39: 667-70. PMID 12144301 DOI: 10.1603/0022-2585-39.4.667  0.34
2002 Tuo W, O'Rourke KI, Zhuang D, Cheevers WP, Spraker TR, Knowles DP. Pregnancy status and fetal prion genetics determine PrPSc accumulation in placentomes of scrapie-infected sheep. Proceedings of the National Academy of Sciences of the United States of America. 99: 6310-5. PMID 11959902 DOI: 10.1073/Pnas.072071199  0.396
2002 Herrmann LM, Baszler TV, Knowles DP, Cheevers WP. PrP(Sc) is not detected in peripheral blood leukocytes of scrapie-infected sheep: determining the limit of sensitivity by immunohistochemistry. Clinical and Diagnostic Laboratory Immunology. 9: 499-502. PMID 11874903 DOI: 10.1128/Cdli.9.2.499-502.2002  0.351
2002 Valdez RA, McGuire TC, Brown WC, Davis WC, Jordan JM, Knowles DP. Selective in vivo depletion of CD4(+) T lymphocytes with anti-CD4 monoclonal antibody during acute infection of calves with Anaplasma marginale. Clinical and Diagnostic Laboratory Immunology. 9: 417-24. PMID 11874888 DOI: 10.1128/Cdli.9.2.417-424.2002  0.624
2001 Rhalem A, Sahibi H, Lasri S, Johnson WC, Kappmeyer LS, Hamidouch A, Knowles DP, Goff WL. Validation of a competitive enzyme-linked immunosorbent assay for diagnosing Babesia equi infections of Moroccan origin and its use in determining the seroprevalence of B. equi in Morocco. Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 13: 249-51. PMID 11482604 DOI: 10.1177/104063870101300311  0.424
2001 Valdez RA, McGuire TC, Brown WC, Davis WC, Knowles DP. Long-term in vivo depletion of functional CD4+ T lymphocytes from calves requires both thymectomy and anti-CD4 monoclonal antibody treatment. Immunology. 102: 426-33. PMID 11328376 DOI: 10.1046/J.1365-2567.2001.01211.X  0.599
2001 Brayton KA, Knowles DP, McGuire TC, Palmer GH. Efficient use of a small genome to generate antigenic diversity in tick-borne ehrlichial pathogens Proceedings of the National Academy of Sciences of the United States of America. 98: 4130-4135. PMID 11274438 DOI: 10.1073/Pnas.071056298  0.421
2001 Bradway DS, De Echaide ST, Knowles DP, Hennager SG, McElwain TF. Sensitivity and specificity of the complement fixation test for detection of cattle persistently infected with Anaplasma marginale Journal of Veterinary Diagnostic Investigation. 13: 79-81. PMID 11243370 DOI: 10.1177/104063870101300117  0.377
2001 Ozyörük F, Cheevers WP, Hullinger GA, McGuire TC, Hutton M, Knowles DP. Monoclonal antibodies to conformational epitopes of the surface glycoprotein of caprine arthritis-encephalitis virus: potential application to competitive-inhibition enzyme-linked immunosorbent assay for detecting antibodies in goat sera. Clinical and Diagnostic Laboratory Immunology. 8: 44-51. PMID 11139194 DOI: 10.1128/Cdli.8.1.44-51.2001  0.332
2001 Li H, Keller J, Knowles DP, Crawford TB. Recognition of another member of the malignant catarrhal fever virus group: An endemic gammaherpesvirus in domestic goats Journal of General Virology. 82: 227-232. PMID 11125175 DOI: 10.1099/0022-1317-82-1-227  0.309
2000 Valdez RA, McGuire TC, Brown WC, Davis WC, Knowles DP. An in vivo model to investigate lymphocyte-mediated immunity during acute hemoparasitic infections. Use of a monoclonal antibody to selectively deplete CD4+ T lymphocytes from thymectomized calves. Annals of the New York Academy of Sciences. 916: 233-6. PMID 11193625 DOI: 10.1111/J.1749-6632.2000.Tb05294.X  0.616
2000 Evermann JF, Howard TH, Dubovi EJ, Knowles DP, Miller LD, Pearson JE, Snider TG, Suarez DL. Controversies and clarifications regarding bovine lentivirus infections Journal of the American Veterinary Medical Association. 217: 1318-1324. PMID 11061383 DOI: 10.2460/Javma.2000.217.1318  0.43
2000 Herrmann LM, Baszler TV, Knowles DP. PrP(c) mRNA, but not PrP(Sc) is found in the salivary glands of scrapie-infected sheep Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1479: 147-154. PMID 11004536 DOI: 10.1016/S0167-4838(00)00056-X  0.37
2000 O'Rourke KI, Baszler TV, Besser TE, Miller JM, Cutlip RC, Wells GAH, Ryder SJ, Parish SM, Hamir AN, Cockett NE, Jenny A, Knowles DP. Preclinical diagnosis of scrapie by immunohistochemistry of third eyelid lymphoid tissue Journal of Clinical Microbiology. 38: 3254-3259. PMID 10970367 DOI: 10.1128/Jcm.38.9.3254-3259.2000  0.326
2000 Kemp RK, Knowles DP, Perry LL, McGuire TC, Besser TE, Cheevers WP. Crossreactive neutralizing antibodies induced by immunization with caprine arthritis-encephalitis virus surface glycoprotein Vaccine. 18: 1282-1287. PMID 10649630 DOI: 10.1016/S0264-410X(99)00181-4  0.316
1999 Arulkanthan A, Brown WC, McGuire TC, Knowles DP. Biased immunoglobulin G1 isotype responses induced in cattle with DNA expressing msp1a of Anaplasma marginale Infection and Immunity. 67: 3481-3487. PMID 10377129 DOI: 10.1128/Iai.67.7.3481-3487.1999  0.33
1999 Kappmeyer LS, Perryman LE, Hines SA, Baszler TV, Katz JB, Hennager SG, Knowles DP. Detection of equine antibodies to Babesia caballi by recombinant B. caballi rhoptry-associated protein 1 in a competitive-inhibition enzyme- linked immunosorbent assay Journal of Clinical Microbiology. 37: 2285-2290. PMID 10364599 DOI: 10.1128/Jcm.37.7.2285-2290.1999  0.368
1999 Molloy JB, Bowles PM, Knowles DP, McElwain TF, Bock RE, Kingston TG, Blight GW, Dalgliesh RJ. Comparison of a competitive inhibition ELISA and the card agglutination test for detection of antibodies to Anaplasma marginale and Anaplasma centrale in cattle. Australian Veterinary Journal. 77: 245-9. PMID 10330556 DOI: 10.1111/J.1751-0813.1999.Tb11712.X  0.304
1998 Herrero MV, Perez E, Goff WL, Torioni De Echaide S, Knowles DP, McElwain TF, Alvarez V, Alvarez A, Buening GM. Prospective study for the detection of Anaplasma marginale Theiler, 1911 (Rickettsiales: Anaplasmataceae) in Costa Rica Annals of the New York Academy of Sciences. 849: 226-233. PMID 9668469 DOI: 10.1111/J.1749-6632.1998.Tb11053.X  0.417
1998 Shkap V, Cohen I, Leibovitz B, Savitsky, Pipano E, Avni G, Shofer S, Giger U, Kappmeyer L, Knowles D. Seroprevalence of Babesia equi among horses in Israel using competitive inhibition ELISA and IFA assays. Veterinary Parasitology. 76: 251-259. PMID 9650862 DOI: 10.1016/S0304-4017(97)00228-8  0.316
1998 O'Rourke KI, Baszler TV, Miller JM, Spraker TR, Sadler-Riggleman I, Knowles DP. Monoclonal antibody F89/160.1.5 Defines a conserved epitope on the ruminant prion protein Journal of Clinical Microbiology. 36: 1750-1755. PMID 9620413 DOI: 10.1128/Jcm.36.6.1750-1755.1998  0.371
1998 Munodzana D, McElwain TF, Knowles DP, Palmer GH. Conformational dependence of Anaplasma marginale major surface protein 5 surface-exposed B-cell epitopes Infection and Immunity. 66: 2619-2624. PMID 9596725 DOI: 10.1128/Iai.66.6.2619-2624.1998  0.332
1998 Torioni De Echaide S, Knowles DP, McGuire TC, Palmer GH, Suarez CE, McElwain TF. Detection of cattle naturally infected with Anaplasma marginale in a region of endemicity by nested PCR and a competitive enzyme-linked immunosorbent assay using recombinant major surface protein 5 Journal of Clinical Microbiology. 36: 777-782. PMID 9508311 DOI: 10.1128/Jcm.36.3.777-782.1998  0.46
1997 Knowles DP, Kappmeyer LS, Perryman LE. Genetic and biochemical analysis of erythrocyte-stage surface antigens belonging to a family of highly conserved proteins of Babesia equi and Theileria species Molecular and Biochemical Parasitology. 90: 69-79. PMID 9497033 DOI: 10.1016/S0166-6851(97)00150-3  0.346
1997 Knowles DP. Laboratory diagnostic tests for retrovirus infections of small ruminants The Veterinary Clinics of North America. Food Animal Practice. 13: 1-11. PMID 9071743 DOI: 10.1016/S0749-0720(15)30361-3  0.446
1997 Knowles D, Torioni de Echaide S, Palmer G, McGuire T, Stiller D, McElwain T. Antibody against an Anaplasma marginale MSP5 epitope common to tick and erythrocyte stages identifies persistently infected cattle. Journal of Clinical Microbiology. 34: 2225-30. PMID 8862589 DOI: 10.1128/Jcm.34.9.2225-2230.1996  0.472
1996 Wyatt CR, Davis WC, Knowles DP, Goff WL, Palmer GH, McGuire TC. Effect on intraerythrocytic Anaplasma marginale of soluble factors from infected calf blood mononuclear cells Infection and Immunity. 64: 4846-4849. PMID 8890250 DOI: 10.1128/Iai.64.11.4846-4849.1996  0.382
1996 Li H, Shen DT, Jessup DA, Knowles DP, Gorham JR, Thorne T, O'Toole D, Crawford TB. Prevalence of antibody to malignant catarrhal fever virus in wild and domestic ruminants by competitive-inhibition ELISA Journal of Wildlife Diseases. 32: 437-443. PMID 8827669 DOI: 10.7589/0090-3558-32.3.437  0.377
1996 Li H, Shen DT, O'Toole D, Davis WC, Knowles DP, Gorham JR, Crawford TB. Malignant catarrhal fever virus. Characterization of a United States isolate and development of diagnostic assays Annals of the New York Academy of Sciences. 791: 198-210. PMID 8784501 DOI: 10.1111/J.1749-6632.1996.Tb53526.X  0.368
1996 Baszler TV, Knowles DP, Dubey JP, Gay JM, Mathison BA, McElwain TF. Serological diagnosis of bovine Neosporosis by Neospora caninum monoclonal antibody-based competitive inhibition enzyme-linked immunosorbent assay Journal of Clinical Microbiology. 34: 1423-1428. PMID 8735092 DOI: 10.1128/Jcm.34.6.1423-1428.1996  0.371
1996 Knowles DP. Control of Babesia equi parasitemia Parasitology Today. 12: 195-198. DOI: 10.1016/0169-4758(96)10007-7  0.305
1995 Robinson MM, Hadlow WJ, Knowles DP, Huff TP, Lacy PA, Marsh RF, Gorham JR. Experimental infection of cattle with the agents of transmissible mink encephalopathy and scrapie Journal of Comparative Pathology. 113: 241-251. PMID 8592050 DOI: 10.1016/S0021-9975(05)80039-8  0.382
1995 Li D, Shen DT, Davis WC, Knowles DP, Gorham JR, Crawford TB. Identification and characterization of the major proteins of malignant catarrhal fever virus Journal of General Virology. 76: 123-129. PMID 7844521 DOI: 10.1099/0022-1317-76-1-123  0.307
1995 Knowles DP, Perryman LE, McElwain TF, Kappmeyer LS, Stiller D, Palmer GH, Visser ES, Hennager SG, Davis WC, McGuire TC. Conserved recombinant antigens of Anaplasma marginale and Babesia equi for serologic diagnosis Veterinary Parasitology. 57: 93-96. PMID 7597796 DOI: 10.1016/0304-4017(94)03113-B  0.35
1995 Li H, Shen DT, O'Toole D, Knowles DP, Gorham JR, Crawford TB. Investigation of sheep-associated malignant catarrhal fever virus infection in ruminants by PCR and competitive inhibition enzyme-linked immunosorbent assay Journal of Clinical Microbiology. 33: 2048-2053. PMID 7559946 DOI: 10.1128/Jcm.33.8.2048-2053.1995  0.394
1995 Ndung'u LW, Aguirre C, Rurangirwa FR, McElwain TF, McGuire TC, Knowles DP, Palmer GH. Detection of Anaplasma ovis infection in goats by major surface protein 5 competitive inhibition enzyme-linked immunosorbent assay. Journal of Clinical Microbiology. 33: 675-9. PMID 7538510 DOI: 10.1128/Jcm.33.3.675-679.1995  0.491
1994 Knowles DP, Kappmeyer LS, Perryman LE. Specific immune responses are required to control parasitemia in Babesia equi infection Infection and Immunity. 62: 1909-1913. PMID 8168957 DOI: 10.1128/Iai.62.5.1909-1913.1994  0.45
1994 Knowles DP, Evermann JF, Shropshire C, VanderSchalie J, Bradway D, Gezon HM, Cheevers WP. Evaluation of agar gel immunodiffusion serology using caprine and ovine lentiviral antigens for detection of antibody to caprine arthritis- encephalitis virus Journal of Clinical Microbiology. 32: 243-245. PMID 8126191 DOI: 10.1128/Jcm.32.1.243-245.1994  0.319
1994 Vidotto MC, McGuire TC, McElwain TF, Palmer GH, Knowles DP. Intermolecular relationships of major surface proteins of Anaplasma marginale Infection and Immunity. 62: 2940-2946. PMID 8005681 DOI: 10.1128/Iai.62.7.2940-2946.1994  0.326
1994 Cheevers WP, Knowles DP, McGuire TC, Baszler TV, Hullinger GA. Caprine arthritis-encephalitis lentivirus (CAEV) challenge of goats immunized with recombinant vaccinia virus expressing CAEV surface and transmembrane envelope glycoproteins Veterinary Immunology and Immunopathology. 42: 237-251. PMID 7810058 DOI: 10.1016/0165-2427(94)90070-1  0.381
1994 Li H, Shen DT, Knowles DP, Gorham JR, Crawford TB. Competitive inhibition enzyme-linked immunosorbent assay for antibody in sheep and other ruminants to a conserved epitope of malignant catarrhal fever virus Journal of Clinical Microbiology. 32: 1674-1679. PMID 7523438 DOI: 10.1128/Jcm.32.7.1674-1679.1994  0.382
1993 Cheevers WP, McGuire TC, Norton LK, Cordery-Cotter R, Knowles DP. Failure of Neutralizing Antibody to Regulate CAE Lentivirus Expression in Vivo Virology. 196: 835-839. PMID 8396810 DOI: 10.1006/Viro.1993.1542  0.352
1993 Hullinger GA, Knowles DP, McGuire TC, Cheevers WP. Caprine Arthritis-Encephalitis Lentivirus SU Is the Ligand for Infection of Caprine Synovial Membrane Cells Virology. 192: 328-331. PMID 8390759 DOI: 10.1006/Viro.1993.1037  0.379
1992 Mcguire TC, Knowles DP, Davis WC, Brassfield AL, Stem TA, Cheevers WP. Transmembrane protein oligomers of caprine arthritis-encephalitis lentivirus are immunodominant in goats with progressive arthritis Journal of Virology. 66: 3247-3250. PMID 1313930 DOI: 10.1128/Jvi.66.5.3247-3250.1992  0.342
1992 Knowles DP, Kappmeyer LS, Stiller D, Hennager SG, Perryman LE. Antibody to a recombinant merozoite protein epitope identifies horses infected with Babesia equi Journal of Clinical Microbiology. 30: 3122-3126. PMID 1280648 DOI: 10.1128/Jcm.30.12.3122-3126.1992  0.433
1992 Visser ES, McGuire TC, Palmer GH, Davis WC, Shkap V, Pipano E, Knowles DP. The Anaplasma marginale msp5 gene encodes a 19-kilodalton protein conserved in all recognized Anaplasma species Infection and Immunity. 60: 5139-5144. PMID 1280624 DOI: 10.1128/Iai.60.12.5139-5144.1992  0.379
1991 Jackson MK, Knowles DP, Stem TA, Harwood WG, Robinson MM, Cheevers WP. Genetic structure of the pol-env region of the caprine arthritis-encephalitis lentivirus genome Virology. 180: 389-394. PMID 1845832 DOI: 10.1016/0042-6822(91)90044-C  0.361
1991 Knowles DP, Perryman LE, Kappmeyer LS, Hennager SG. Detection of equine antibody to Babesia equi merozoite proteins by a monoclonal antibody-based competitive inhibition enzyme-linked immunosorbent assay Journal of Clinical Microbiology. 29: 2056-2058. PMID 1774334 DOI: 10.1128/Jcm.29.9.2056-2058.1991  0.304
1991 Lichtensteiger CA, Knowles DP, McGuire TC, Cheevers WP. Recombinant gp135 envelope glycoproteins of caprine arthritis-encephalitis lentivirus variants inhibit homologous and heterologous variant-specific neutralizing antibodies. Virology. 185: 2-9. PMID 1718084 DOI: 10.1016/0042-6822(91)90747-Y  0.344
1991 Knowles DP, Perryman LE, Goff WL, Miller CD, Harrington RD, Gorham JR. A monoclonal antibody defines a geographically conserved surface protein epitope of Babesia equi merozoites. Infection and Immunity. 59: 2412-7. PMID 1711016 DOI: 10.1128/Iai.59.7.2412-2417.1991  0.414
1991 Knowles DP, Cheevers WP, McGuire TC, Brassfield AL, Harwood WG, Stem TA. Structure and genetic variability of envelope glycoproteins of two antigenic variants of caprine arthritis-encephalitis lentivirus Journal of Virology. 65: 5744-5750. PMID 1656067 DOI: 10.1128/Jvi.65.11.5744-5750.1991  0.305
1991 Cheevers WP, Knowles DP, Norton LK. Neutralization-resistant antigenic variants of caprine arthritis-encephalitis lentivirus associated with progressive arthritis Journal of Infectious Diseases. 164: 679-685. PMID 1654355 DOI: 10.1093/Infdis/164.4.679  0.399
1990 Knowles D, Cheevers W, McGuire T, Stem T, Gorham J. Severity of arthritis is predicted by antibody response to gp135 in chronic infection with caprine arthritis-encephalitis virus. Journal of Virology. 64: 2396-8. PMID 2325206 DOI: 10.1128/Jvi.64.5.2396-2398.1990  0.377
1988 Goff W, Barbet A, Stiller D, Palmer G, Knowles D, Kocan K, Gorham J, McGuire T. Detection of Anaplasma-marginale-infected tick vectors by using a cloned DNA probe. Proceedings of the National Academy of Sciences of the United States of America. 85: 919-23. PMID 3422471 DOI: 10.1073/Pnas.85.3.919  0.443
1988 Cheevers WP, Stem TA, Knowles DP, McGuire TC. Precursor polypeptides of caprine arthritis-encephalitis lentivirus structural proteins. The Journal of General Virology. 675-81. PMID 3351481 DOI: 10.1099/0022-1317-69-3-675  0.334
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